AR124250A1 - Anticuerpos - Google Patents
AnticuerposInfo
- Publication number
- AR124250A1 AR124250A1 ARP210103379A ARP210103379A AR124250A1 AR 124250 A1 AR124250 A1 AR 124250A1 AR P210103379 A ARP210103379 A AR P210103379A AR P210103379 A ARP210103379 A AR P210103379A AR 124250 A1 AR124250 A1 AR 124250A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibodies
- il22r1
- attenuates
- interleukin
- inhibits
- Prior art date
Links
- 102100030703 Interleukin-22 Human genes 0.000 abstract 4
- 108010074109 interleukin-22 Proteins 0.000 abstract 4
- 230000003993 interaction Effects 0.000 abstract 1
- 108010027445 interleukin-22 receptor Proteins 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a anticuerpos que se unen a IL22 e inhiben su interacción con uno o más de sus ligandos naturales. Se proporcionan ejemplos específicos de tales anticuerpos. También se proporcionan los usos terapéuticos de los anticuerpos y los métodos para generarlos. Reivindicación 1: Un anticuerpo aislado caracterizado porque se une a la interleuquina 22 (IL22) e inhibe o atenúa la unión de IL22 al receptor 1 de IL22 unido a la membrana (IL22R1).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20212127 | 2020-12-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR124250A1 true AR124250A1 (es) | 2023-03-01 |
Family
ID=73740238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP210103379A AR124250A1 (es) | 2020-12-07 | 2021-12-06 | Anticuerpos |
Country Status (13)
Country | Link |
---|---|
US (1) | US20230416357A1 (es) |
EP (1) | EP4255925A1 (es) |
JP (1) | JP2023551983A (es) |
KR (1) | KR20230118128A (es) |
CN (1) | CN116802211A (es) |
AR (1) | AR124250A1 (es) |
AU (1) | AU2021398385A1 (es) |
BR (1) | BR112023008265A2 (es) |
CA (1) | CA3200836A1 (es) |
CO (1) | CO2023007280A2 (es) |
IL (1) | IL303294A (es) |
MX (1) | MX2023006649A (es) |
WO (1) | WO2022122652A1 (es) |
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-
2021
- 2021-12-06 EP EP21819151.8A patent/EP4255925A1/en active Pending
- 2021-12-06 KR KR1020237022428A patent/KR20230118128A/ko unknown
- 2021-12-06 AU AU2021398385A patent/AU2021398385A1/en active Pending
- 2021-12-06 CN CN202180092179.6A patent/CN116802211A/zh active Pending
- 2021-12-06 WO PCT/EP2021/084400 patent/WO2022122652A1/en active Application Filing
- 2021-12-06 MX MX2023006649A patent/MX2023006649A/es unknown
- 2021-12-06 CA CA3200836A patent/CA3200836A1/en active Pending
- 2021-12-06 AR ARP210103379A patent/AR124250A1/es unknown
- 2021-12-06 JP JP2023534303A patent/JP2023551983A/ja active Pending
- 2021-12-06 BR BR112023008265A patent/BR112023008265A2/pt unknown
- 2021-12-06 IL IL303294A patent/IL303294A/en unknown
- 2021-12-06 US US18/253,240 patent/US20230416357A1/en active Pending
-
2023
- 2023-06-01 CO CONC2023/0007280A patent/CO2023007280A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2023551983A (ja) | 2023-12-13 |
CO2023007280A2 (es) | 2023-06-09 |
KR20230118128A (ko) | 2023-08-10 |
US20230416357A1 (en) | 2023-12-28 |
CA3200836A1 (en) | 2022-06-16 |
WO2022122652A1 (en) | 2022-06-16 |
CN116802211A (zh) | 2023-09-22 |
BR112023008265A2 (pt) | 2024-02-06 |
EP4255925A1 (en) | 2023-10-11 |
MX2023006649A (es) | 2023-06-21 |
AU2021398385A1 (en) | 2023-07-13 |
IL303294A (en) | 2023-07-01 |
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