FI108147B - Menetelmä proteiinituotteiden tuottamiseksi Aspergillus oryzaella ja promoottori käytettävksi Aspergilluksessa - Google Patents

Menetelmä proteiinituotteiden tuottamiseksi Aspergillus oryzaella ja promoottori käytettävksi Aspergilluksessa Download PDF

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Publication number
FI108147B
FI108147B FI871144A FI871144A FI108147B FI 108147 B FI108147 B FI 108147B FI 871144 A FI871144 A FI 871144A FI 871144 A FI871144 A FI 871144A FI 108147 B FI108147 B FI 108147B
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Prior art keywords
gene
amylase
promoter
sequence
fragment
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FI871144A
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English (en)
Finnish (fi)
Swedish (sv)
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FI871144A (fi
FI871144A0 (fi
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Helle Fabricius Woeldike
Tove Christensen
Esper Boel
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Novozymes As
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI871144A 1986-03-17 1987-03-16 Menetelmä proteiinituotteiden tuottamiseksi Aspergillus oryzaella ja promoottori käytettävksi Aspergilluksessa FI108147B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK122686A DK122686D0 (da) 1986-03-17 1986-03-17 Fremstilling af proteiner
DK122686 1986-03-17

Publications (3)

Publication Number Publication Date
FI871144A0 FI871144A0 (fi) 1987-03-16
FI871144A FI871144A (fi) 1987-09-18
FI108147B true FI108147B (fi) 2001-11-30

Family

ID=8102403

Family Applications (2)

Application Number Title Priority Date Filing Date
FI871144A FI108147B (fi) 1986-03-17 1987-03-16 Menetelmä proteiinituotteiden tuottamiseksi Aspergillus oryzaella ja promoottori käytettävksi Aspergilluksessa
FI20011797A FI112376B (fi) 1986-03-17 2001-09-12 TAKA-amylaasipromoottori

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20011797A FI112376B (fi) 1986-03-17 2001-09-12 TAKA-amylaasipromoottori

Country Status (9)

Country Link
EP (3) EP1502952A3 (es)
JP (4) JPH0665316B2 (es)
AT (2) ATE98993T1 (es)
CA (1) CA1341593C (es)
DE (2) DE3788524T3 (es)
DK (1) DK122686D0 (es)
ES (1) ES2061446T5 (es)
FI (2) FI108147B (es)
IE (2) IE940343L (es)

Families Citing this family (993)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198345A (en) * 1985-04-15 1993-03-30 Gist-Brocades N.V. Vectors in use in filamentous fungi
AU607398B2 (en) * 1985-08-29 1991-03-07 Genencor Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
US6004785A (en) * 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
US5766912A (en) * 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
ATE125865T1 (de) * 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.
US5292448A (en) * 1988-05-10 1994-03-08 Lever Brothers Company, Division Of Conopco, Inc. Enzymatic detergent composition
CA1341226C (en) * 1988-08-16 2001-05-01 Wim Van Hartingsveldt Gene replacement as a tool for the construction of aspergillus strains
JP2757945B2 (ja) * 1989-09-08 1998-05-25 キッコーマン株式会社 アルカリプロテアーゼプロモーター、同ターミネーター及びこれらからなる遺伝子発現用ユニット、並びにアルカリプロテアーゼのゲノム遺伝子
WO1991013971A1 (en) * 1990-03-13 1991-09-19 Hawaii Biotechnology Group, Inc. Neurospora expression system
DE4009676A1 (de) * 1990-03-26 1991-10-02 Rhein Biotech Proz & Prod Gmbh Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen
JPH04121194A (ja) * 1990-09-11 1992-04-22 Tax Adm Agency アスペルギルスオリゼの新規プロモーター
ATE123524T1 (de) * 1991-03-22 1995-06-15 Novo Nordisk As Herstellungsverfahren für chymosin.
WO1992016634A1 (en) * 1991-03-22 1992-10-01 Novo Nordisk A/S A process for producing heme proteins
JPH06507071A (ja) 1991-05-01 1994-08-11 ノボザイムス アクティーゼルスカブ 安定化酵素
EP0599859A1 (en) * 1991-06-25 1994-06-08 Novo Nordisk A/S Mammalian pancreatic lipase and variant thereof
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
DK39693D0 (da) † 1993-04-02 1993-04-02 Novo Nordisk As Enzym
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost
BR9407767A (pt) 1993-10-08 1997-03-18 Novo Nordisk As Variante de enzima &-amilase uso da mesma construção de DNA vetor de express o recombinante célula processos para produzir uma &-amilase hibrida e para preparar uma variante de uma &-amilase aditivo detergente e composições detergentes
EP1707624A3 (en) 1993-10-08 2007-01-03 Novozymes A/S Amylase variants
BE1008737A3 (fr) * 1994-01-28 1996-07-02 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1009488A4 (fr) * 1994-06-17 1997-04-01 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
BE1008267A3 (fr) * 1994-01-28 1996-03-05 Solvay Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration.
DE69534513T2 (de) 1994-03-08 2006-07-27 Novozymes A/S Neuartige alkalische zellulasen
AU2067795A (en) 1994-03-29 1995-10-17 Novo Nordisk A/S Alkaline bacillus amylase
WO1995035385A1 (en) * 1994-06-17 1995-12-28 Novo Nordisk A/S A FUNGUS WHEREIN THE areA GENE HAS BEEN MODIFIED AND AN areA GENE FROM ASPERGILLUS ORYZAE
GB9413419D0 (en) * 1994-07-04 1994-08-24 Danisco Amylase enzyme
US6051431A (en) * 1994-07-22 2000-04-18 Dsm N.V. Selection marker gene free recombinant strains: a method for obtaining them and the use of these strains
US5935836A (en) * 1994-07-29 1999-08-10 Rohm Enzyme Finland Oy Actinomadura xylanase sequences and methods of use
US6300114B1 (en) 1994-07-29 2001-10-09 Rohm Enzyme Finland Oy Sequences of xylanase and xylanase expression vectors
US7816129B2 (en) 1994-07-29 2010-10-19 Ab Enzymes Gmbh Production and secretion of proteins of bacterial origin in filamentous fungi
WO1996013578A1 (en) * 1994-10-26 1996-05-09 Novo Nordisk A/S Enzymatic detergent composition
US6127142A (en) * 1994-12-21 2000-10-03 Chr. Hansen A/S Microbially derived enzymes having enhanced milk clotting activity and method of producing same
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
ATE315083T1 (de) 1995-03-17 2006-02-15 Novozymes As Neue endoglukanase
US5919746A (en) * 1995-03-30 1999-07-06 Novo Nordisk A/S Alkaline lipolytic enzyme
AU5002096A (en) * 1995-03-30 1996-10-16 Novo Nordisk A/S Alkaline lipolytic enzyme
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
DE69604491T3 (de) 1995-06-07 2008-09-25 Danisco A/S Methode zur verbesserung der eigenschaften von mehlteig, sowie zusammensetzung zur teigverbesserung und verbesserte nahrungsmittel
EP0850295B2 (en) 1995-09-08 2011-11-30 Novozymes A/S Prevention of back-staining in stone washing
EP0866872A1 (en) * 1995-12-15 1998-09-30 Novo Nordisk A/S A FUNGUNS WHEREIN THE areA, pepC AND/OR pepE GENES HAVE BEEN INACTIVATED
DK0877801T3 (da) 1996-01-19 2005-08-29 Novozymes Biotech Inc Morfologiske mutanter af trådsvampe
EP0904360B1 (en) 1996-04-30 2013-07-31 Novozymes A/S alpha-AMYLASE MUTANTS
JP2000501294A (ja) * 1996-06-10 2000-02-08 ノボ ノルディスク バイオテック，インコーポレイティド アスペルギラス・オリザイ（Ａｓｐｅｒｇｉｌｌｕｓ ｏｒｙｚａｅ）の５―アミノレブリン酸シンターゼおよびそれをコードする核酸
DE69738158T2 (de) 1996-07-05 2008-06-19 Novozymes A/S Alpha-Amylase Transkriptionsfaktor
EP0932667B1 (en) 1996-11-04 2008-10-01 Novozymes A/S Subtilase variants and compositions
EP2278001B1 (en) 1996-11-04 2013-10-23 Novozymes A/S Protease variants and compositions
DE69716711T3 (de) 1996-12-09 2010-06-10 Novozymes A/S Verringerung von phosphorhaltigen Substanzen in Speiseölen mit hohem Anteil an nicht-hydratisierbarem Phosphor unter Verwendung einer Phospholipase, eine Phospholipase aus fädenförmigen Pilz, welche eine Phospholipase A und/oder B-Aktivität aufweist
US5821102A (en) * 1997-01-21 1998-10-13 Novo Nordisk Biotech Inc. Nucleic acids encoding polyeptides having absidia lipase activity
US5891669A (en) 1997-03-17 1999-04-06 Novo Nordisk A/S, Novoalle, Methods for producing polypeptides in respiratory-deficient cells
ATE414775T1 (de) 1997-05-16 2008-12-15 Novozymes Inc Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
EP2386568B1 (en) 1997-10-30 2014-08-06 Novozymes A/S Alpha-amylase mutants
CN100494363C (zh) 1997-12-22 2009-06-03 诺维信公司 糖氧化酶及其在焙烤中的用途
DK1042461T3 (da) * 1997-12-22 2007-09-24 Dsm Ip Assets Bv Ekspressionskloning i filiforme svampe
CN103352033B (zh) 1998-02-27 2016-05-11 诺维信公司 麦芽α淀粉酶变体
CN101024826B (zh) 1998-06-10 2014-09-03 诺沃奇梅兹有限公司 新的甘露聚糖酶
ES2188190T5 (es) 1998-07-21 2007-11-16 Danisco A/S Producto alimentario.
AU6188599A (en) 1998-10-26 2000-05-15 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
EP2298873A1 (en) 1998-11-27 2011-03-23 Novozymes A/S Lipolytic enzyme variants
US7220542B2 (en) 2000-07-17 2007-05-22 Van Den Brink Johannes Maarten Expression cloning in filamentous fungi
EP2278016B1 (en) 1999-03-22 2012-09-26 Novozymes Inc. Promoter sequences derived from Fusarium Venenatum and uses thereof
EP1818396B1 (en) 1999-03-30 2014-06-18 Novozymes A/S Alpha-amylase variants
EP1169434B1 (en) 1999-03-31 2009-02-11 Novozymes A/S Polypeptides having alkaline alpha-amylase activity and nucleic acids encoding same
CN1234854C (zh) 1999-03-31 2006-01-04 诺维信公司 具有碱性α－淀粉酶活性的多肽以及编码该多肽的核酸
JP4526638B2 (ja) 1999-06-01 2010-08-18 月桂冠株式会社 タンパク質の高発現システム
WO2001004273A2 (en) 1999-07-09 2001-01-18 Novozymes A/S Glucoamylase variant
NZ531394A (en) 1999-08-31 2005-10-28 Novozymes As Residual protease II (RPII) and variants thereof useful in detergent compositions
EP1230351A1 (en) 1999-11-10 2002-08-14 Novozymes A/S Fungamyl-like alpha-amylase variants
AR027509A1 (es) 2000-01-10 2003-04-02 Maxygen Aps Conjugados g-csf
US6350599B1 (en) 2000-01-12 2002-02-26 Novozymes A/S Pullulanase variants and methods for preparing such variants with predetermined properties
AU783512B2 (en) 2000-02-11 2005-11-03 Bayer Healthcare Llc Factor VII or VIIa-like molecules
EP2298875B1 (en) 2000-03-08 2015-08-12 Novozymes A/S Variants with altered properties
AU2001242299A1 (en) 2000-03-14 2001-09-24 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
EP2119773A1 (en) 2000-06-26 2009-11-18 Novozymes A/S Lipolytic enzymes from strains of fusarium and acremonium
EP2308979A3 (en) 2000-08-01 2011-05-04 Novozymes A/S Alpha-amylase mutants with altered properties
AU2001285719B2 (en) 2000-09-05 2007-08-23 Novozymes A/S Manganese lipoxygenase
EP1975229A3 (en) 2000-10-13 2009-03-18 Novozymes A/S Alpha-amylase variant with altered properties
MXPA03007619A (es) 2001-02-27 2003-12-04 Maxygen Aps Nuevas moleculas similares a interferon beta.
IL157842A0 (en) 2001-03-22 2004-03-28 Novo Nordisk Healthcare Ag Coagulation factor vii derivatives
EP1383874B1 (en) 2001-04-20 2009-12-23 Novozymes A/S Variants of lipoxygenase and their use
EP1950305A1 (en) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr a genes and uses thereof
EP1423513B1 (en) 2001-05-15 2009-11-25 Novozymes A/S Alpha-amylase variant with altered properties
NZ528260A (en) 2001-05-18 2005-09-30 Danisco Method of improving dough and bread quality with the addition of an enzyme that hydrolyses a glycolipid and a phospholipid and incapable of hydrolysing a triglyceride or monoglyceride
ES2521615T3 (es) 2001-06-06 2014-11-13 Novozymes A/S Endo-beta-1,4-glucanasa
CN1620501A (zh) 2001-06-26 2005-05-25 诺维信公司 具有纤维二糖水解酶i活性的多肽和编码多肽的多核苷酸
US7063962B2 (en) 2001-07-20 2006-06-20 Novozymes A/S DNA sequences for regulating transcription
EP1432794B1 (en) 2001-09-27 2011-11-09 Novo Nordisk Health Care AG Human coagulation factor vii polypeptides
EP1448768B1 (en) 2001-12-19 2006-03-08 DSM IP Assets B.V. Method for the inactivation of amylase in the presence of protease
US7404977B2 (en) 2001-12-21 2008-07-29 Dsm Ip Assets B.V. Rennets
JP4495904B2 (ja) * 2002-03-01 2010-07-07 天野エンザイム株式会社 改変プロモーター
ATE460488T1 (de) 2002-04-22 2010-03-15 Novozymes Inc Verfahren zur herstellung von varianten einer dna-sequenz in filamentösen pilzen
WO2003089617A2 (en) 2002-04-22 2003-10-30 Novozymes Biotech, Inc. Methods for increasing homologous recombination of a nucleic acid sequence
EP2216405A1 (en) 2002-05-03 2010-08-11 Monsanto Technology LLC Speed specific USP promoters for expressing genes in plants
WO2003100048A1 (en) 2002-05-29 2003-12-04 Dsm Ip Assets B.V. Method for the purification of microbial protease
AU2003273256A1 (en) 2002-08-30 2004-03-19 Novozymes Biotech, Inc. Methods for producing mammalian trypsins
ATE494368T1 (de) 2002-10-01 2011-01-15 Novozymes As Polypeptide der gh-61-familie
JP2004141029A (ja) 2002-10-23 2004-05-20 Amano Enzyme Inc イソマルトース生成酵素の遺伝子が欠損した、真菌類に属する微生物
JP4490284B2 (ja) 2002-11-18 2010-06-23 ノボザイムス，インコーポレイティド 菌類細胞において遺伝子を発現するためのプロモーター変異体
MXPA05006071A (es) 2002-12-11 2005-09-30 Novozymes As Composicion detergente.
DE60310264T2 (de) 2002-12-17 2007-07-05 Novozymes A/S Thermostabile alpha-amylase
US7348168B2 (en) 2002-12-20 2008-03-25 Novozymes A/S Polypeptides having cellobiohydrolase II activity and polynucleotides encoding same
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
DK1599278T3 (da) 2003-01-17 2011-07-18 Danisco Fremgangsmåde til fremstilling af en hydroxysyreester
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007653A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US20060205628A1 (en) 2003-02-18 2006-09-14 Novozymes A/S Detergent compositions
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
ATE441664T1 (de) 2003-03-31 2009-09-15 Novozymes Inc Verfahren zur produktion biologischer substanzen in enzymmangelmutanten von aspergillus niger
NZ553115A (en) 2003-04-28 2008-04-30 Novozymes As Method of producing a phospholipase which comprises processing an expressed fungal peptide so as to cleave off a peptide from the C- terminal end and/or a peptide from the N-terminal end to obtain a core peptide
EP1622921B1 (en) 2003-05-02 2010-06-16 Novozymes Inc. Variants of beta-glucosidases
US20060236414A1 (en) 2003-06-19 2006-10-19 Novozymes A/S Proteases and methods for producing them
DK1639106T3 (da) 2003-06-19 2010-09-27 Novozymes As Proteaser
WO2004113551A1 (en) 2003-06-25 2004-12-29 Novozymes A/S Process for the hydrolysis of starch
WO2005001064A2 (en) 2003-06-25 2005-01-06 Novozymes A/S Polypeptides having alpha-amylase activity and polypeptides encoding same
WO2005003311A2 (en) 2003-06-25 2005-01-13 Novozymes A/S Enzymes for starch processing
DK2617826T3 (en) 2003-08-25 2015-10-12 Novozymes Inc Variants of glucosidhydrolase
ES2381110T3 (es) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Polipéptidos de factor VII de coagulación
JP4880469B2 (ja) 2003-10-23 2012-02-22 ノボザイムス アクティーゼルスカブ 洗剤中で改良された安定性を有するプロテアーゼ
WO2005047499A1 (en) 2003-10-28 2005-05-26 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
MXPA06004463A (es) 2003-10-28 2006-06-27 Novozymes North America Inc Enzimas hibridas.
EP1682655B1 (en) 2003-10-30 2009-09-02 Novozymes A/S Carbohydrate-binding modules
US7985569B2 (en) 2003-11-19 2011-07-26 Danisco Us Inc. Cellulomonas 69B4 serine protease variants
BRPI0416797A (pt) 2003-11-19 2007-04-17 Genencor Int serina proteases, ácidos nucléicos codificando enzimas de serina e vetores e células hospedeiras incorporando as mesmas
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
US7906307B2 (en) 2003-12-24 2011-03-15 Danisco A/S Variant lipid acyltransferases and methods of making
JP5697294B2 (ja) 2003-12-24 2015-04-08 デュポン ニュートリション バイオサイエンシーズ エーピーエス 糖脂質アシル基転移酵素変異体及びその製造方法
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
WO2005066339A2 (en) 2004-01-06 2005-07-21 Novozymes A/S Polypeptides of alicyclobacillus sp.
DK1713825T3 (da) 2004-01-30 2012-11-05 Novozymes Inc Polypeptider med cellulolytisk forøgende aktivitet og polynukleotider der koder for samme
CN101389645B (zh) 2004-02-12 2016-08-03 诺维信股份有限公司 具有木聚糖酶活性的多肽和编码它的多核苷酸
NZ549198A (en) 2004-02-25 2009-05-31 Novozymes As Fungal cell wall degrading lysozyme for use as an inhibitor of dental biofilms
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
PT1729797E (pt) 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
WO2005100582A2 (en) 2004-03-25 2005-10-27 Novozymes Inc. Methods for degrading or converting plant cell wall polysaccharides
AU2005233326B2 (en) 2004-04-16 2010-09-23 Dsm Ip Assets B.V. Fungal promoters for expressing a gene in a fungal cell
US7148404B2 (en) 2004-05-04 2006-12-12 Novozymes A/S Antimicrobial polypeptides
US9045748B2 (en) 2004-05-27 2015-06-02 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a DNA library
WO2005117756A2 (en) 2004-05-27 2005-12-15 Genencor International, Inc. Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
DE602005017034D1 (de) 2004-06-14 2009-11-19 Novozymes As Signalpeptid zur herstellung eines polypeptids
MXPA06014649A (es) 2004-06-21 2007-03-12 Novozymes As Proteasas.
US20080044853A1 (en) 2004-06-21 2008-02-21 Novozymes A/S Stably Maintained Multiple Copies of at Least Two Orf in the Same Orientation
CN101031643B (zh) 2004-06-29 2014-05-21 诺维信股份有限公司 具有α-葡糖苷酶活性的多肽及编码其的多核苷酸
BRPI0512776A (pt) 2004-07-05 2008-04-08 Novozymes As variante de uma alfa-amilase tipo termamil originária, construto de dna, vetor de expressão recombinante, célula, composição, aditivo de detergente, composição detergente, composição de lavagem de roupa manual ou automática, uso de uma variante de alfa-amilase ou composição, e, método de produzir uma variante
WO2006008508A1 (en) 2004-07-16 2006-01-26 Danisco A/S Enzymatic oil-degumming method
EP2258836B1 (en) 2004-09-10 2016-05-04 Novozymes North America, Inc. Methods for preventing, removing, reducing, or disrupting biofilm
US7666630B2 (en) 2004-09-30 2010-02-23 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encoding same
EP2272964A3 (en) 2004-10-04 2011-08-31 Novozymes A/S Polypeptides having phytase activity and polynucleotides encoding same
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
WO2006038128A2 (en) 2004-10-04 2006-04-13 Danisco A/S Citrobacter freundii phytase and homologues
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
WO2006053565A2 (en) 2004-11-19 2006-05-26 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2006069289A2 (en) 2004-12-22 2006-06-29 Novozymes North America, Inc Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2006072256A2 (en) 2005-01-10 2006-07-13 Novozymes A/S Process for the production of fatty acid alkyl esters from triglycerides and alcohols employing mixtures of two lipolytic enzymes
DK2410048T3 (en) 2005-01-24 2016-11-28 Dsm Ip Assets Bv A process for the preparation of a compound of interest in a filamentous fungal cell
EP1700904A1 (en) 2005-03-11 2006-09-13 Unilever N.V. Liquid detergent composition
EP1700907A1 (en) 2005-03-11 2006-09-13 Unilever N.V. Liquid bleaching composition
DK1863834T3 (da) 2005-03-22 2010-11-01 Novozymes As Polypeptider og nukleinsyrer, der koder disse
AR053066A1 (es) 2005-04-26 2007-04-18 Novozymes As Arabinofuranosidasas
EP1877551B2 (en) 2005-04-27 2014-02-26 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2377884A1 (en) 2005-05-10 2011-10-19 Neoloch Aps Neuritogenic peptides
EP1913138B1 (en) 2005-07-29 2016-08-24 Abbott Laboratories GmbH Processes for the manufacture of pancreatin powder with low virus content
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
WO2007019859A2 (en) 2005-08-16 2007-02-22 Novozymes A/S Polypeptides of strain bacillus sp. p203
EP1754781B1 (en) 2005-08-19 2013-04-03 The Procter and Gamble Company A solid laundry detergent composition comprising anionic detersive surfactant and a calcium-augmented technology
BRPI0614968A2 (pt) 2005-08-26 2011-10-18 Novozymes As polipeptìdeo, polinucleotìdeo, construção de ácido nucléico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir o polipeptìdeo, e um polinucleotìdeo, e para matar ou inibir o crescimento de células microbianas, planta transgênica, parte de planta ou célula de planta, composição, e, uso de um polipeptìdeo antimicrobiano
JP2009507497A (ja) 2005-09-12 2009-02-26 ノボザイムス ノース アメリカ，インコーポレイティド 油の酵素的エステル交換
EP1926817A2 (en) 2005-09-14 2008-06-04 Novo Nordisk Health Care AG Human coagulation factor vii polypeptides
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
NZ589570A (en) 2005-09-30 2012-06-29 Novozymes Inc Methods for enhancing the degradation or conversion of cellulosic material
CN101292024B (zh) 2005-10-17 2012-04-18 诺维信公司 用于表达抗体的真菌突变体的用途
US8071089B2 (en) 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
US20080280328A1 (en) 2005-11-18 2008-11-13 Novozymes A/S Glucoamylase Variants
WO2007062936A2 (en) * 2005-11-29 2007-06-07 Dsm Ip Assets B.V. Dna binding site of a transcriptional activator useful in gene expression
WO2007093177A2 (en) 2006-02-14 2007-08-23 Vladimir Berezin Metallothionein-derived peptide fragments
BRPI0708949B1 (pt) 2006-03-20 2017-04-04 Novozymes As métodos para degradar ou converter um material celulósico, para produzir uma susbtância, e para produzir um polipeptídeo tendo atividade endoglucanase, e, célula microbiana recombinante
BRPI0710217A2 (pt) 2006-03-30 2011-08-02 Novozymes Inc polipeptìdeo, polinucleotìdeo, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir o polipeptìdeo, para produzir um mutante a partir de uma célula precursora, para produzir uma proteìna, para produzir um polinucleotìdeo, para degradar ou converter um material celulósico, para produzir uma substáncia e para inibir a expressão de um polinucleotìdeo em uma célula, célula mutante, planta transgênica, parte de planta ou célula de planta, e, molécula de rna de filamento duplo
EP2383330A1 (en) 2006-03-31 2011-11-02 Novozymes A/S A stabilized liquid enzyme composition
ES2387203T3 (es) 2006-04-04 2012-09-17 Novozymes A/S Variantes de fitasa
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
EA015925B1 (ru) 2006-06-29 2011-12-30 ДСМ АйПи АССЕТС Б.В. Способ получения полипептидов
DK2059590T3 (en) 2006-07-14 2015-02-23 Novozymes Inc Methods for preparation of secreted polypeptides having biological activity
JP2009543560A (ja) 2006-07-14 2009-12-10 ノボザイムス，インコーポレイティド 真菌細胞中の遺伝子発現を上昇させる方法
EP2046819B1 (en) 2006-07-21 2015-03-18 Novozymes, Inc. Methods of increasing secretion of polypeptides having biological activity
US9447397B2 (en) 2006-10-10 2016-09-20 Danisco Us Inc. Glucoamylase variants with altered properties
DK2089524T3 (da) 2006-11-30 2013-01-21 Novozymes As DNase ekspression i rekombinante værtsceller
US8105812B2 (en) 2006-12-18 2012-01-31 Danisco Us Inc. Laccases, compositions and methods of use
CN101563451B (zh) 2006-12-21 2012-09-05 丹尼斯科美国公司 芽孢杆菌属物种195的α-淀粉酶多肽的组合物及用途
BRPI0720801A2 (pt) 2007-01-25 2014-09-16 Dupont Nutrition Biosci Aps Produção de um lipídio aciltranfersase a partir de células transformadas de bacillus licheniformis.
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
US20080220498A1 (en) 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US20100112638A1 (en) 2007-02-15 2010-05-06 Cornelis Maria Jacobus Sagt Recombinant host cell for the production of a compound of interest
CN101617035A (zh) 2007-02-20 2009-12-30 诺维信公司 用于洗衣的酶泡沫处理
EP2851424B1 (en) 2007-03-09 2016-09-21 Novozymes A/S Thermostable asparaginases
CN101679987A (zh) 2007-03-09 2010-03-24 丹尼斯科美国公司 嗜碱芽孢杆菌物种α-淀粉酶变体、包括α-淀粉酶变体的组合物以及使用方法
CN101636490B (zh) 2007-03-14 2012-05-16 丹尼斯科美国公司 里氏木霉α-淀粉酶是一种生麦芽糖酶
EP2129781B1 (en) 2007-03-26 2014-01-22 Novozymes A/S Hafnia phytase
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
DK2147107T3 (da) 2007-05-09 2011-10-24 Novozymes As Fremgangsmåde til ekspressionskloning, som er egnet til selektion af bibliotekskloner, der producerer et polypeptid af interesse
DK2147104T3 (en) 2007-05-21 2015-12-14 Danisco Us Inc USING A ASPARAGINPROTEASE- (NSP24) SIGNAL SEQUENCE FOR heterologous protein EXPRESSION
SG148934A1 (en) 2007-06-11 2009-01-29 Novozymes As A process for combined biopolishing and bleach clean-up
US9808595B2 (en) 2007-08-07 2017-11-07 Boston Scientific Scimed, Inc Microfabricated catheter with improved bonding structure
CA2695830A1 (en) 2007-08-08 2009-02-12 Novozymes Biopharma Dk A/S Transferrin variants and conjugates
GB0715751D0 (en) * 2007-08-13 2007-09-19 Tmo Renewables Ltd Thermophilic micro-organisms for ethanol production
EP2193195B1 (en) 2007-09-18 2014-12-17 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
US8592194B2 (en) 2007-10-09 2013-11-26 Danisco Us Inc. Glucoamylase variants with altered properties
PL2514818T3 (pl) 2007-10-09 2014-11-28 Danisco Us Inc Odmiany glukoamylazy
US7618801B2 (en) 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
NZ584434A (en) 2007-11-05 2011-12-22 Danisco Us Inc VARIANTS OF BACILLUS sp. TS-23 ALPHA-AMYLASE WITH ALTERED PROPERTIES
WO2009061381A2 (en) 2007-11-05 2009-05-14 Danisco Us Inc., Genencor Division Alpha-amylase variants with altered properties
JP2009118783A (ja) * 2007-11-15 2009-06-04 Gekkeikan Sake Co Ltd 糸状菌タンパク質分泌生産の改善
ES2527586T3 (es) 2007-11-20 2015-01-27 Danisco Us Inc. Variantes de glucoamilasa con propiedades modificadas
US7867745B2 (en) 2007-11-27 2011-01-11 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
BRPI0820615B1 (pt) 2007-12-06 2020-05-12 Novozymes A/S Célula microbiana hospedeira recombinante, métodos para produzir um polipeptídeo tendo atividade de acetil-xilano esterase, método para produzir uma proteína e método de degradar um material contendo xilano
SG162265A1 (en) 2007-12-13 2010-07-29 Danisco Us Inc Compositions and methods for producing isoprene
AU2008343105A1 (en) 2007-12-19 2009-07-09 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2546338A1 (en) 2008-01-02 2013-01-16 Danisco US Inc. A process of obtaining ethanol without glucoamylase using pseudomonas saccharophila g4-amylase and variants thereof
EP2245060B1 (en) 2008-02-01 2017-11-01 Novozymes A/S Liquid enzyme composition
WO2009100102A2 (en) 2008-02-04 2009-08-13 Danisco Us Inc., Genencor Division Ts23 alpha-amylase variants with altered properties
RU2510662C2 (ru) 2008-03-26 2014-04-10 Новозимс А/С Стабилизированные жидкие ферментные композиции
EP3118309B1 (en) 2008-04-18 2020-09-16 Danisco US Inc. Buttiauxella sp. phytase variants
US8173410B2 (en) 2008-04-23 2012-05-08 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
EP2123772A1 (en) 2008-04-29 2009-11-25 DSM IP Assets B.V. Beta-lactam antibiotic producing strains
MX2010011721A (es) 2008-04-30 2010-11-30 Danisco Inc Nuevas variantes de alfa-amilasa quimericas.
WO2009133464A2 (en) 2008-04-30 2009-11-05 Danisco A/S Oxidation process
AU2009246166B2 (en) 2008-05-15 2014-09-18 Tetherex Pharmaceuticals Corporation Anti-PSGL-1 antibodies and methods of identification and use
EP2291526B1 (en) 2008-06-06 2014-08-13 Danisco US Inc. Saccharification enzyme composition with Bacillus subtilis alpha-amylase
JP2011521661A (ja) 2008-06-06 2011-07-28 ノボザイムス アクティーゼルスカブ ファミリー４４キシログルカナーゼのバリアント
DK2447361T3 (en) 2008-06-06 2015-01-05 Danisco Us Inc Alpha-amylase (AMYS) variants of Geobacillus stearothermophilus with improved properties
JP5647976B2 (ja) 2008-06-06 2015-01-07 ダニスコ・ユーエス・インク 変異体微生物プロテアーゼを含む組成物及び方法
DK2297312T3 (da) 2008-06-06 2013-12-16 Danisco Us Inc Alpha-amylasevarianter af Bacillus subtilis og fremgangsmåder til anvendelse heraf
US9040278B2 (en) 2008-06-06 2015-05-26 Danisco Us Inc. Production of glucose from starch using alpha-amylases from Bacillus subtilis
MY156256A (en) 2008-07-02 2016-01-29 Danisco Us Inc Compositions and methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges
ES2569913T3 (es) 2008-07-07 2016-05-13 Basf Se Composición de enzima que comprende partículas poliméricas que contienen enzima
BRPI0918453A2 (pt) 2008-09-15 2019-12-17 Danisco Us Inc sistemas usando cultura de células para a produção de isopreno
WO2010031062A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using the archaeal lower mevalonate pathway
WO2010031068A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Reduction of carbon dioxide emission during isoprene production by fermentation
CA2737195A1 (en) 2008-09-15 2010-03-18 The Goodyear Tire & Rubber Company Conversion of prenyl derivatives to isoprene
WO2010036515A1 (en) 2008-09-25 2010-04-01 Danisco Us Inc. Alpha-amylase blends and methods for using said blends
US8206962B2 (en) 2008-09-26 2012-06-26 Novozymes A/S Hafnia phytase variants
EP2647692A3 (en) 2008-11-11 2014-01-22 The Procter and Gamble Company Compositions and methods comprising serine protease variants
BRPI0921827A2 (pt) 2008-11-11 2016-09-27 Danisco Us Inc composições e métodos compreendendo uma variante de subtilisina
US20100152088A1 (en) 2008-11-11 2010-06-17 Estell David A Compositions and methods comprising a subtilisin variant
KR20110095260A (ko) 2008-11-11 2011-08-24 다니스코 유에스 인크. 하나 이상의 조합가능 돌연변이를 포함하는 바실러스 서브틸리신
WO2010059413A2 (en) 2008-11-20 2010-05-27 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
CN102300986A (zh) 2008-12-04 2011-12-28 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
WO2010074972A1 (en) 2008-12-15 2010-07-01 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
WO2010077775A1 (en) 2008-12-16 2010-07-08 Novozymes, Inc. Polypeptides having alpha-mannosidase activity and polynucleotides encoding same
US8633030B2 (en) 2008-12-16 2014-01-21 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
US8426158B2 (en) 2008-12-19 2013-04-23 Novozymes, Inc. Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase
DK2379712T3 (en) 2008-12-19 2017-05-08 Novozymes Inc Methods for Increasing Hydrolysis of Cellulosic Material in the Presence of Cellobiose Dehydrogenase
US8338121B2 (en) 2008-12-19 2012-12-25 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
CN102325889A (zh) 2008-12-19 2012-01-18 诺维信股份有限公司 增加纤维素材料水解的方法
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
CN102292436A (zh) 2008-12-23 2011-12-21 丹尼斯科公司 具有木聚糖酶活性的多肽
CA2748887A1 (en) 2008-12-30 2010-07-08 Danisco Us Inc. Methods of producing isoprene and a co-product
AU2010206181B2 (en) 2009-01-21 2015-01-15 Novozymes A/S Polypeptides having esterase activity and nucleic acids encoding the same
CN102388134A (zh) 2009-01-28 2012-03-21 诺维信股份有限公司 具有β-葡糖苷酶活性的多肽和编码该多肽的多核苷酸
US8629324B2 (en) 2009-01-30 2014-01-14 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
LT2393828T (lt) 2009-02-03 2017-01-25 Amunix Operating Inc. Prailginti rekombinantiniai polipeptidai ir juos apimančios kompozicijos
JP2012516878A (ja) 2009-02-06 2012-07-26 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ 精製プロセス
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP3243835B1 (en) 2009-02-11 2024-04-10 Albumedix Ltd Albumin variants and conjugates
JP2010183885A (ja) * 2009-02-13 2010-08-26 Kobe Univ タンパク質の製造方法およびそれに用いる発現ベクター
US20120277117A1 (en) 2009-02-27 2012-11-01 Adel Zayed Hydroponic apparatus and methods of use
WO2010104675A1 (en) 2009-03-10 2010-09-16 Danisco Us Inc. Bacillus megaterium strain dsm90-related alpha-amylases, and methods of use, thereof
AU2010221862A1 (en) 2009-03-11 2011-10-06 Dsm Ip Assets B.V. Preparation of alpha-ketopimelic acid
WO2010106068A1 (en) 2009-03-17 2010-09-23 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
EP2408805A2 (en) 2009-03-18 2012-01-25 Danisco US Inc. Fungal cutinase from magnaporthe grisea
BRPI1013425A2 (pt) 2009-03-23 2015-09-01 Danisco Us Inc Aciltransferases relacionadas com cal a e métodos de uso das mesmas
WO2010108918A1 (en) 2009-03-24 2010-09-30 Novozymes A/S Polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
BRPI1010238A2 (pt) 2009-04-01 2015-08-25 Danisco Us Inc Composições e métodos que comprendem variantes de alfa-amilase com propriedades alteradas
CN102388131B (zh) 2009-04-08 2014-04-30 丹尼斯科美国公司 盐单胞菌属菌株WDG195相关α-淀粉酶及其使用方法
CN102414323B (zh) 2009-04-22 2015-07-08 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的重组多肽的方法
WO2010124146A2 (en) 2009-04-23 2010-10-28 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
EP2248893A1 (en) 2009-05-06 2010-11-10 Novozymes A/S DFPase Enzymes from Octopus Vulgaris
MX2011012313A (es) 2009-05-19 2011-12-12 Danisco Uso.
DK3591046T3 (da) 2009-05-19 2021-07-26 Dupont Nutrition Biosci Aps Amylasepolypeptide
DK2435561T3 (en) 2009-05-29 2018-11-05 Novozymes Inc PROCEDURES FOR IMPROVING THE DEGRADATION OR CONVERSION OF CELLULOSE SUBSTANCES
US8278507B2 (en) 2009-06-02 2012-10-02 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
TWI434921B (zh) 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
TW201412988A (zh) 2009-06-17 2014-04-01 Danisco Us Inc 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造
JP2012531197A (ja) 2009-06-25 2012-12-10 デュポン ニュートリション バイオサイエンシーズ エーピーエス タンパク質
BR112012000260B1 (pt) 2009-07-07 2020-11-17 Novozymes A/S célula hospedeira microbiana transgênica, métodos para produzir um polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, construções de ácido nucleico, vetor de expressão, polipeptídeo isolado tendo atividade de intensificação celulolítica, e, polinucleotídeo isolado que codifica o mesmo
WO2011006982A2 (en) 2009-07-17 2011-01-20 Rigshospitalet Inhibitors of complement activation
AU2010275672A1 (en) 2009-07-22 2012-02-02 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
WO2011015633A1 (en) 2009-08-07 2011-02-10 Novozymes A/S Method of producing a sweet protein
CA2771071C (en) 2009-08-07 2020-03-10 Danisco Us Inc. Alpha-amylase blend for starch processing and method of use thereof
CN102712915B (zh) 2009-08-19 2014-12-10 丹尼斯科美国公司 具有改良比活和/或热稳定性的葡糖淀粉酶的组合变体
PE20121504A1 (es) 2009-08-19 2012-11-05 Dupont Nutrition Biosci Aps Variantes de glucoamilasa
MX2012002095A (es) 2009-08-21 2012-04-10 Novozymes As Polipeptidos que tienen actividad de isoamilasa y polinucleotidos que codifican los mismos.
EP2470559B1 (en) 2009-08-24 2017-03-22 Amunix Operating Inc. Coagulation factor ix compositions and methods of making and using same
EP2478096B1 (en) 2009-09-17 2017-05-24 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2478095A1 (en) 2009-09-18 2012-07-25 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US20120172280A1 (en) 2009-09-25 2012-07-05 Novozymes A/S Protease Variants
JP6204018B2 (ja) 2009-09-25 2017-09-27 ノボザイムス アクティーゼルスカブ プロテアーゼ変異体の使用
WO2011041397A1 (en) 2009-09-29 2011-04-07 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN107338233A (zh) 2009-09-29 2017-11-10 诺维信股份有限公司 具有木聚糖酶活性的多肽和编码该多肽的多核苷酸
CN102695720B (zh) 2009-09-30 2018-02-16 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
US8586829B2 (en) 2009-09-30 2013-11-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2491122A1 (en) 2009-10-23 2012-08-29 Novozymes Inc. Cellobiohydrolase variants and polynucleotides encoding same
EP2491121A2 (en) 2009-10-23 2012-08-29 Danisco US Inc. Methods for reducing blue saccharide
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
ES2574054T3 (es) 2009-11-06 2016-06-14 Novozymes, Inc. Polipéptidos con actividad de xilanasa y polinucleótidos que los codifican
CA2780179A1 (en) 2009-11-06 2011-05-12 Novozymes, Inc. Compositions for saccharification of cellulosic material
DK2496693T3 (en) 2009-11-06 2018-01-22 Novozymes Inc Polypeptides with cellobiohydrolase activity and polynucleotides encoding them
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
WO2011066560A1 (en) 2009-11-30 2011-06-03 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
MX2012006096A (es) 2009-11-30 2012-07-03 Novozymes North America Inc Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos.
CA2782036C (en) 2009-12-01 2019-01-15 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
ES2583259T3 (es) 2009-12-01 2016-09-20 Novo Nordisk A/S Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
WO2011072099A2 (en) 2009-12-09 2011-06-16 Danisco Us Inc. Compositions and methods comprising protease variants
CN106929494B (zh) 2009-12-09 2021-05-14 诺维信公司 产生gh8木聚糖酶变体的方法
ES2668202T3 (es) 2009-12-11 2018-05-17 Novozymes A/S Variantes de proteasa
MX2012007168A (es) 2009-12-21 2012-07-23 Danisco Us Inc Composiciones de detergentes que contienen lipasa thermobifida fusca y metodos de uso de esta.
US20120258900A1 (en) 2009-12-21 2012-10-11 Danisco Us Inc. Detergent compositions containing bacillus subtilis lipase and methods of use thereof
WO2011084417A1 (en) 2009-12-21 2011-07-14 Danisco Us Inc. Detergent compositions containing geobacillus stearothermophilus lipase and methods of use thereof
EP2501792A2 (en) 2009-12-29 2012-09-26 Novozymes A/S Gh61 polypeptides having detergency enhancing effect
CN103068975B (zh) 2010-01-04 2018-03-20 诺维信公司 α‑淀粉酶变体和编码该变体的多核苷酸
US8617856B2 (en) 2010-01-07 2013-12-31 Wisconsin Alumni Research Foundation Fatty acid-producing hosts
EP2357220A1 (en) 2010-02-10 2011-08-17 The Procter & Gamble Company Cleaning composition comprising amylase variants with high stability in the presence of a chelating agent
US9896673B2 (en) 2010-02-10 2018-02-20 Novozymes A/S Compositions of high stability alpha amylase variants
BR112012020802A2 (pt) 2010-02-11 2015-09-15 Dsm Ip Assets Bv célula hospedeira capaz de produzir enzimas úteis para degradação de material lignocelulósico
US8815559B2 (en) 2010-02-18 2014-08-26 Danisco Us Inc. Amylase from nesterenkonia and methods of use, thereof
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
JP5833576B2 (ja) 2010-02-25 2015-12-16 ノボザイムス アクティーゼルスカブ リゾチームの変異体及びそれをコードするポリヌクレオチド
BR112012020309A2 (pt) 2010-03-03 2015-11-03 Novozymes As "variante isolado de uma xilanase precursora, polinucleotídeo isolado, célula hospedeira, métodos para produzir e para obter um variante, planta transgênica, parte da planta ou célula da planta, e, métodos para degradar um material contendo xilano, para tratar uma polpa, e para produzir xilose."
CA2791841C (en) 2010-03-05 2023-01-03 Rigshospitalet Chimeric inhibitor molecules of complement activation
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
US20110229921A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
CA2794113A1 (en) 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants
CN102918151B (zh) 2010-03-31 2015-09-09 诺维信股份有限公司 纤维二糖水解酶变体及编码其的多核苷酸
DK2558484T3 (en) 2010-04-14 2016-03-29 Novozymes As Polypeptides having glucoamylase activity and polynucleotides encoding them
WO2011130222A2 (en) 2010-04-15 2011-10-20 Danisco Us Inc. Compositions and methods comprising variant proteases
CN108410585A (zh) 2010-05-06 2018-08-17 宝洁公司 具有蛋白酶变体的消费品
WO2011150157A2 (en) 2010-05-28 2011-12-01 Danisco Us Inc. Detergent compositions containing streptomyces griseus lipase and methods of use thereof
DK2576606T3 (en) 2010-06-04 2015-02-23 Novozymes Inc Preparation of C4 dicarboxylic acid in filamentous fungi
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
US8933282B2 (en) 2010-06-17 2015-01-13 Danisco Us Inc. Fuel compositions comprising isoprene derivatives
BR112012028031A2 (pt) 2010-06-21 2019-09-24 Novozymes Inc célula hospedeira, e , métodos para produzir um ácido dicarboxílico c4 e para aumentar a produção de ácido dicarboxílico c4.
CN103080126B (zh) 2010-06-21 2016-05-11 诺维信股份有限公司 具有c4-二羧酸转运蛋白活性的多肽和编码该多肽的多核苷酸
CN103068989B (zh) 2010-06-25 2015-09-09 诺维信公司 具有启动子活性的多核苷酸
EP2585602A1 (en) 2010-06-25 2013-05-01 Novozymes A/S Polynucleotides having promoter activity
DK2585591T3 (en) 2010-06-25 2015-02-23 Novozymes As Polynucleotides with leader sequence function
WO2011163558A1 (en) 2010-06-25 2011-12-29 Abbott Laboratories Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies
WO2012003379A1 (en) 2010-06-30 2012-01-05 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
EP2588616B1 (en) 2010-07-01 2018-11-14 DSM IP Assets B.V. A method for the production of a compound of interest
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
US8865448B2 (en) 2010-07-30 2014-10-21 Cleanvantage Llc Aspergillus containing beta-glucosidase, beta-glucosidases and nucleic acids encoding the same
WO2012021408A1 (en) 2010-08-12 2012-02-16 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a dioxy compound and uses thereof
PL2606114T3 (pl) 2010-08-17 2015-08-31 Novozymes As Sposób warzenia piwa
WO2012022777A1 (en) 2010-08-19 2012-02-23 Novozymes A/S Induced sporulation screening method
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
WO2012028483A1 (en) 2010-08-30 2012-03-08 Novozymes A/S A concentrated soak wash
CN103492545A (zh) 2010-08-30 2014-01-01 诺维信公司 两次浸泡洗涤
WO2012030858A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having hemicellulolytic activity and polynucleotides encoding same
EP2611901B1 (en) 2010-08-30 2016-05-11 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
US9267126B2 (en) 2010-08-30 2016-02-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2611914A1 (en) 2010-08-30 2013-07-10 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012030811A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2012031910A2 (en) 2010-09-10 2012-03-15 Dsm Ip Assets B.V. Method for preparing alpha-ketopimelic acid by c1-elongation
EP2616483A1 (en) 2010-09-16 2013-07-24 Novozymes A/S Lysozymes
JP5759132B2 (ja) * 2010-09-21 2015-08-05 月桂冠株式会社 糸状菌ペプチダーゼの生産方法
WO2012044836A1 (en) 2010-09-30 2012-04-05 Novozymes, Inc. Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN103282489B (zh) 2010-09-30 2016-12-14 诺维信股份有限公司 具有纤维素分解增强活性的多肽变体及其编码多核苷酸
JP2012075369A (ja) * 2010-09-30 2012-04-19 Toyota Motor Corp シス作用エレメント及びその利用
DK2622071T3 (en) 2010-10-01 2016-03-07 Novozymes As Polypeptides having endopeptidase activity and polynucleotides encoding them
WO2012044915A2 (en) 2010-10-01 2012-04-05 Novozymes, Inc. Beta-glucosidase variants and polynucleotides encoding same
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
CN103443271A (zh) 2010-10-27 2013-12-11 丹尼斯科美国公司 用于增加异戊二烯产量的异戊二烯合酶变体
EP2632943A1 (en) 2010-10-29 2013-09-04 Novozymes A/S Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same
EP2633030A1 (en) 2010-10-29 2013-09-04 Novozymes A/S Recombinant n-propanol and isopropanol production
WO2012061517A1 (en) 2010-11-02 2012-05-10 Novozymes, Inc. Methods of pretreating cellulosic material with a gh61 polypeptide
EP2635594B1 (en) 2010-11-04 2017-01-11 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
CN103298932B (zh) 2010-11-08 2016-08-10 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
WO2012064350A1 (en) 2010-11-08 2012-05-18 Novozymes A/S Polypeptides Having Glucoamylase Activity and Polynucleotides Encoding Same
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
MX356647B (es) 2010-11-12 2018-06-07 Novozymes As Polipeptidos que tienen actividad de fosfolipasa c y polinucleotidos que codifican los mismos.
EP2638153B1 (en) 2010-11-12 2017-07-12 Novozymes Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
BR112013010129A2 (pt) 2010-11-18 2016-07-05 Novozymes Inc polipeptídeo gh61 quimérico isolado, polinucleotídeo isolado, célula hospedeira, métodos para produzir um polipeptídeo gh61 quimérico, para degradas ou converter um material celulóstico, para sintetizar um produto de fermentação, para fermentar um material celulósico e para limpar ou lavar uma superfície dura ou roupa para lavar, planta transgênica, parte da planta ou célula de planta, uso do polipeptídeo gh61 quimérico, composição detergente, e, formulação de caldo ou composição de cultura de células completas
DK2646558T3 (en) 2010-11-30 2016-10-03 Novozymes Inc Promoters for expression of genes in a fungal cell
WO2012078656A1 (en) 2010-12-06 2012-06-14 Novozymes North America, Inc. Methods of hydrolyzing oligomers in hemicellulosic liquor
US8924138B2 (en) 2010-12-07 2014-12-30 Vnomics Corp. System and method for measuring and reducing vehicle fuel waste
US9284588B2 (en) 2010-12-16 2016-03-15 Novozymes, Inc. Promoters for expressing genes in a fungal cell
EP2654781B1 (en) 2010-12-21 2018-01-24 Selexys Pharmaceuticals Corporation Anti-p-selectin antibodies and methods of their use and identification
US8691541B2 (en) 2010-12-22 2014-04-08 Danisco Us Inc. Biological production of pentose sugars using recombinant cells
WO2012088462A1 (en) 2010-12-22 2012-06-28 Danisco Us Inc. Compositions and methods for improved isoprene production using two types of ispg enzymes
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
MX337919B (es) 2011-01-26 2016-03-28 Novozymes As Polipeptidos que tienen actividad de celobiohidrolasa y polinucleotidos que codifican los mismos.
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
DK2668268T3 (en) 2011-01-26 2017-09-11 Novozymes Inc POLYPEPTIDES WITH CELLOBIO HYDROLASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
CN110628803A (zh) 2011-01-26 2019-12-31 诺维信公司 具有纤维二糖水解酶活性的多肽及编码该多肽的多核苷酸
US9434972B2 (en) 2011-01-31 2016-09-06 Novozymes North America, Inc. Processes for enzymatic refining of pretreated cellulosic material for saccharification
CA2825628A1 (en) 2011-02-23 2012-08-30 Dupont Nutrition Biosciences Aps Method
DK2678352T3 (en) 2011-02-23 2018-03-05 Novozymes Inc Polypeptides with cellulolysis enhancing activity and polynucleotides encoding them
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
WO2012122518A1 (en) 2011-03-09 2012-09-13 Novozymes A/S Methods of increasing the cellulolytic enhancing activity of a polypeptide
US9409958B2 (en) 2011-03-10 2016-08-09 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20140106398A1 (en) 2011-03-11 2014-04-17 Dsm Ip Assets B.V. Vector-host system
EP3333258A3 (en) 2011-03-25 2018-07-25 Novozymes A/S Method for degrading or converting cellulosic material
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
EP2691519A1 (en) 2011-03-31 2014-02-05 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
EP2694537A1 (en) 2011-04-08 2014-02-12 Danisco US Inc. Compositions
CN103649308A (zh) 2011-04-28 2014-03-19 诺维信股份有限公司 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸
BR112013026675A2 (pt) 2011-04-29 2016-11-29 Danisco Us Inc composições detergentes contendo mananase de bacillus sp., e métodos de uso das mesmas
EP2702072A1 (en) 2011-04-29 2014-03-05 Danisco US Inc. Detergent compositions containing bacillus agaradhaerens mannanase and methods of use thereof
EP2712363A1 (en) 2011-04-29 2014-04-02 Danisco US Inc. Detergent compositions containing geobacillus tepidamans mannanase and methods of use thereof
CN103797126A (zh) 2011-04-29 2014-05-14 诺维信股份有限公司 用于增强纤维素材料的降解或转化的方法
CN106065381B (zh) 2011-05-05 2019-07-26 宝洁公司 包含丝氨酸蛋白酶变体的组合物和方法
CN103764823B (zh) 2011-05-05 2018-05-11 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
EP2710132A1 (en) 2011-05-19 2014-03-26 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
WO2012159009A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
MX349517B (es) 2011-06-24 2017-08-02 Novozymes As Polipeptidos que tienen actividad de proteasa y polinucleotidos que codifican los mismos.
DK3421595T3 (da) 2011-06-30 2020-10-26 Novozymes As Alfa-amylasevarianter
DK3543333T3 (da) 2011-06-30 2022-02-14 Novozymes As Fremgangsmåde til screening af alfa-amylaser
EP2729572B1 (en) 2011-07-06 2019-03-20 Novozymes A/S Alpha amylase variants and polynucleotides encoding same
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
WO2013010783A1 (en) 2011-07-15 2013-01-24 Novozymes A/S Lipase variants and polynucleotides encoding same
CN109022518A (zh) 2011-07-22 2018-12-18 诺维信北美公司 用于预处理纤维素材料和改进其水解的方法
CA2838758A1 (en) 2011-08-04 2013-02-07 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2739727B1 (en) 2011-08-04 2016-05-25 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9506044B2 (en) 2011-08-10 2016-11-29 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
CN103827297B (zh) 2011-08-10 2018-06-22 诺维信公司 具有过氧化酶活性的多肽及编码该多肽的多核苷酸
US9487761B2 (en) 2011-08-10 2016-11-08 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9000138B2 (en) 2011-08-15 2015-04-07 Novozymes A/S Expression constructs comprising a Terebella lapidaria nucleic acid encoding a cellulase, host cells, and methods of making the cellulase
US20140295027A1 (en) 2011-08-19 2014-10-02 Novozymes A/S Polypeptides Having Protease Activity
CN103917649A (zh) 2011-08-19 2014-07-09 诺维信股份有限公司 用于生产c4-二羧酸的重组微生物
EP2748321A2 (en) 2011-08-24 2014-07-02 Novozymes, Inc. Methods for obtaining positive transformants of a filamentous fungal host cell
BR112014004190A2 (pt) 2011-08-24 2017-03-01 Novozymes Inc método para construir uma cepa fúngida filamentosa, cepa fúngida filamentosa, método para produzir múltiplos polipeptídeos recombinantes, e, construto em tandem
US9476036B2 (en) 2011-08-24 2016-10-25 Novozymes, Inc. Cellulolytic enzyme compositions and uses thereof
WO2013028927A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof
WO2013029496A1 (en) 2011-08-26 2013-03-07 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2013036526A1 (en) 2011-09-06 2013-03-14 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2013034106A1 (en) 2011-09-09 2013-03-14 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CN103945861B (zh) 2011-09-12 2018-06-05 阿穆尼克斯运营公司 胰高血糖素样肽-2组合物及其制备和使用方法
EP2756091A1 (en) 2011-09-13 2014-07-23 Novozymes North America, Inc. Methods of hydrolyzing and fermenting cellulosic material
WO2013043910A1 (en) 2011-09-20 2013-03-28 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
US20150031091A1 (en) 2011-09-30 2015-01-29 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CN103930438A (zh) 2011-09-30 2014-07-16 诺维信股份有限公司 具有β-葡糖苷酶活性的嵌合多肽和对其进行编码的多核苷酸
JP2014528726A (ja) 2011-09-30 2014-10-30 ノボザイムス，インコーポレイティド デヒドロゲナーゼ変異体およびこれをコードするポリヌクレオチド
US9745556B2 (en) 2011-10-04 2017-08-29 University Of Florida Research Foundation, Incorporated Variants of glycerol dehydrogenase having D-lactate dehydrogenase activity and uses thereof
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013053801A1 (en) 2011-10-11 2013-04-18 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
KR102034007B1 (ko) 2011-10-17 2019-10-18 노보자임스 에이/에스 알파-아밀라아제 변이체 및 이를 암호화하는 폴리뉴클레오티드
KR102046075B1 (ko) 2011-10-17 2019-11-18 노보자임스 에이/에스 알파-아밀라아제 변이체 및 이를 암호화하는 폴리뉴클레오티드
AU2012328562A1 (en) 2011-10-28 2014-03-13 Danisco Us Inc. Variant maltohexaose-forming alpha-amylase variants
EP2773656B1 (en) 2011-10-31 2019-06-19 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20130109055A1 (en) 2011-10-31 2013-05-02 Bp Corporation North America Inc. Use of mammalian promoters in filamentous fungi
WO2013067026A1 (en) 2011-10-31 2013-05-10 Bp Corporation North America Inc. Use of plant promoters in filamentous fungi
EP2780449B1 (en) 2011-11-18 2018-04-11 Novozymes, Inc. Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
CN109112118A (zh) 2011-11-21 2019-01-01 诺维信股份有限公司 Gh61多肽变体以及编码所述变体的多核苷酸
BR112014011387A2 (pt) 2011-11-22 2017-05-02 Novozymes Inc polipeptídeo e polinucleotídeo isolados, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, e uma proteína, e para inibir a expressão de um polipeptídeo, planta transgênica, parte da planta ou célula de planta, molécula de rna, processos para degradar ou converter um material celulósico ou contendo xilano, para sintetizar um produto de fermentação, e para fermentar um material celulósico ou contendo xilano, e, formulação de caldo completo ou composição de cultura de célula
US9663775B2 (en) 2011-11-25 2017-05-30 Novozymes A/S Polypeptides having lysozyme activity and polynucleotides encoding same
US9624481B2 (en) 2011-12-01 2017-04-18 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
US9169469B2 (en) 2011-12-02 2015-10-27 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013079533A1 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2791330B1 (en) 2011-12-16 2017-07-26 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
BR112014014697A2 (pt) 2011-12-19 2020-10-27 Novozymes, Inc. polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos para produzir um polipeptídeo e uma proteína, para gerar oxigênio molecular, e para remover peróxido de hidrogênio do tecido, processos para degradar ou converter um material celulósico, e para produzir um produto de fermentação, e, formulação de caldo integral ou composição de cultura de células
WO2013096603A2 (en) 2011-12-20 2013-06-27 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
CN104066838A (zh) 2011-12-22 2014-09-24 丹尼斯科美国公司 变体α-淀粉酶及其使用方法
ES2667318T3 (es) 2011-12-28 2018-05-10 Novozymes A/S Polipéptidos con actividad de proteasa
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
WO2013110766A1 (en) 2012-01-26 2013-08-01 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
CN108148823B (zh) 2012-02-03 2023-03-14 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
CN104080902B (zh) 2012-02-03 2018-08-03 宝洁公司 具有脂肪酶的用于表面处理的组合物和方法
EP2812024B1 (en) 2012-02-09 2018-04-11 Var2 Pharmaceuticals ApS Targeting of chondroitin sulfate glycans
RS63870B1 (sr) 2012-02-15 2023-01-31 Bioverativ Therapeutics Inc Sastavi faktora viii i postupci za pravljenje i upotrebu istih
WO2013123457A1 (en) 2012-02-15 2013-08-22 Biogen Idec Ma Inc. Recombinant factor viii proteins
PT2817325T (pt) 2012-02-20 2019-10-01 Novozymes As Polipéptidos que têm atividade da endoglucanase e polinucleotídeos codificando mesmos
CN104204198B (zh) 2012-04-02 2018-09-25 诺维信公司 脂肪酶变体以及编码其的多核苷酸
DK2841570T3 (en) 2012-04-23 2018-03-12 Novozymes As POLYPEPTIDES WITH GLUCURONYL STERASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
CN104245929A (zh) 2012-04-23 2014-12-24 诺维信公司 具有α-葡糖醛酸糖苷酶活性的多肽以及编码其的多核苷酸
BR112014026625A2 (pt) 2012-04-27 2017-07-18 Novozymes Inc E Novozymes As variante do polipeptídeo, polinucleotídeo isolado, célula hospedeira recombinante, métodos para produção de uma variante do polipeptídeo e para obtenção de uma variante do polipeptídeo, planta, parte de planta ou célula de planta transgênica, processos para degradação ou conversão de um material celulósico, para produção de um produto da fermentação e para fermentação de um material celulósico, composição, e, formulação ou composição de cultura celular de caldo inteiro
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
CN113201519A (zh) 2012-05-07 2021-08-03 诺维信公司 具有黄原胶降解活性的多肽以及编码其的核苷酸
MX2014013402A (es) 2012-05-11 2014-11-26 Danisco Inc Uso de alfa-amilasa de aspergillus clavatus para sacarificacion.
EP2855659A1 (en) 2012-05-31 2015-04-08 Novozymes A/S Improved selection in fungi
CN104364371B (zh) 2012-05-31 2018-10-23 诺维信公司 具有有机磷水解酶活性的多肽
ES2673872T3 (es) 2012-06-05 2018-06-26 The Board Of Trustees Of The Leland Stanford Junior University Mimético del péptido NCAM para su uso en el tratamiento de trastorno de depresión mayor
DK2825643T3 (da) 2012-06-08 2021-11-08 Danisco Us Inc Variant-alfa-amylaser med forbedret aktivitet over for stivelsespolymerer
BR112014031526A2 (pt) 2012-06-19 2017-08-01 Dsm Ip Assets Bv promotores para expressar um gene em uma célula
AU2013279440B2 (en) 2012-06-20 2016-10-06 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
MX2015000312A (es) 2012-07-12 2015-04-10 Novozymes As Polipeptidos que tienen actividad lipasa y polinucleotidos que los codifican.
MX357482B (es) 2012-07-19 2018-07-11 Dsm Ip Assets Bv Cepa deficiente en agse.
PT3553172T (pt) 2012-08-16 2023-01-27 Novozymes As Método para tratamento de tecido com endoglucanase
US9765315B2 (en) 2012-08-16 2017-09-19 Bangladesh Jute Research Institute Cellulose and/or hemicelluloses degrading enzymes from Macrophomina phaseolina and uses thereof
DK2885407T3 (en) 2012-08-16 2018-07-16 Bangladesh Jute Res Institute DESTROYING ENZYMES FROM MACROPHOMINA PHASEOLINA AND ITS APPLICATIONS
WO2014028434A2 (en) 2012-08-16 2014-02-20 Danisco Us Inc. Method of using alpha-amylase from aspergillus clavatus and pullulanase for saccharification
BR112015003257A2 (pt) 2012-08-17 2017-11-14 Novozymes As variante de asparaginase, métodos para produção de um produto alimentar a partir de um material alimentar, para produção de uma variante de asparaginase e para obtenção de uma variante de asparaginase, polinucleotídeo isolado, constructo de ácido nucleico, vetor de expressão, e, célula hospedeira
WO2014028833A1 (en) 2012-08-17 2014-02-20 Novozymes A/S Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
EP2888361A1 (en) 2012-08-22 2015-07-01 Novozymes A/S Metalloprotease from exiguobacterium
MX2015002099A (es) 2012-08-22 2015-05-11 Dupont Nutrition Biosci Aps Variantes que tienen actividad glucoamilasa.
US9315791B2 (en) 2012-08-22 2016-04-19 Novozymes A/S Metalloproteases from alicyclobacillus
US9771570B2 (en) 2012-09-05 2017-09-26 Novozymes A/S Polypeptides having protease activity
US20140073022A1 (en) 2012-09-10 2014-03-13 Wisconsin Alumni Research Foundation Production of polyhydroxyalkanoates with a defined composition from an unrelated carbon source
WO2014092832A2 (en) 2012-09-19 2014-06-19 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
US9951339B2 (en) 2012-09-19 2018-04-24 Dsm Ip Assets B.V. Cell modification method using essential genes as markers and optionally recycling these
EP3586610B1 (en) 2012-10-08 2024-09-25 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2014056916A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
US9453207B2 (en) 2012-10-12 2016-09-27 Novozymes A/S Polypeptides having peroxygenase activity
EP2906687B1 (en) 2012-10-12 2018-08-15 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056927A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
EP2906686B1 (en) 2012-10-12 2018-08-29 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056917A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
CN104718287B (zh) 2012-10-12 2018-02-06 诺维信公司 具有过氧合酶活性的多肽
EP2906693A1 (en) 2012-10-15 2015-08-19 Novo Nordisk Health Care AG Coagulation factor vii polypeptides
US10226744B2 (en) 2012-10-19 2019-03-12 Danisco Us Inc Stabilization of biomimetic membranes
US20150275194A1 (en) 2012-10-24 2015-10-01 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
AU2013337999A1 (en) 2012-10-31 2015-04-02 Danisco Us Inc. Beta-glucosidase from Magnaporthe grisea
EP2914719A1 (en) 2012-10-31 2015-09-09 Danisco US Inc. Compositions and methods of use
MX2015005424A (es) 2012-10-31 2015-08-05 Danisco Inc Beta-glucosidasa de neurospora crassa.
US20160060611A1 (en) 2012-11-05 2016-03-03 Danisco Us Inc. Compositions and methods comprising thermolysin protease variants
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
WO2014081622A1 (en) 2012-11-20 2014-05-30 Danisco Us Inc. Amylase with maltogenic properties
US9624270B2 (en) 2012-11-29 2017-04-18 Mississippi State University Engineering the production of a conformational variant of occidiofungin that has enhanced inhibitory activity against fungal species
WO2014086659A2 (en) 2012-12-06 2014-06-12 Ahmedabad Textile Industry's Research Association Method for enzymatical preparation of textiles
WO2014088934A1 (en) 2012-12-07 2014-06-12 Danisco Us Inc. Compositions and methods of use
EP2929021A1 (en) 2012-12-07 2015-10-14 Danisco US Inc. Compositions and methods of use
EP2929028A1 (en) 2012-12-07 2015-10-14 Novozymes A/S Method for generating site-specific mutations in filamentous fungi
WO2014090161A1 (en) 2012-12-11 2014-06-19 Novozymes A/S Polypeptides having phospholipase c activity and polynucleotides encoding same
CA2894513A1 (en) 2012-12-14 2014-06-19 Danisco Us Inc. Method of using alpha-amylase from aspergillus fumigatus and isoamylase for saccharification
CN104870639A (zh) 2012-12-14 2015-08-26 诺维信公司 具有纤维素分解增强活性的多肽以及编码它们的多核苷酸
EP2935574B1 (en) 2012-12-17 2019-11-13 Novozymes A/S Alpha-amylases and polynucleotides encoding same
US20150344858A1 (en) 2012-12-19 2015-12-03 Danisco Us Inc. Novel mannanase, compositions and methods of use thereof
WO2014099798A1 (en) 2012-12-19 2014-06-26 Novozymes A/S Polypeptides having cellulolytic enhancinc activity and polynucleotides encoding same
US20160010128A1 (en) 2012-12-20 2016-01-14 Danisco Us Inc. Method of using alpha-amylase from aspergillus terreus and pullulanase for saccharification
BR112015014396B1 (pt) 2012-12-21 2021-02-02 Novozymes A/S Composição, construto de ácido nucleico ou vetor de expressão, microorganismo recombinante, métodos de melhoria do valor nutricional de uma ração animal, aditivo de ração animal, e, uso de uma ou mais proteases
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
WO2014099523A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Alpha-amylase variants
BR112015014624A2 (pt) 2012-12-24 2017-10-10 Novozymes As polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, método para tratamento de têxtil
EP2941485B1 (en) 2013-01-03 2018-02-21 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
DK3202900T3 (en) 2013-02-04 2019-04-08 Dsm Ip Assets Bv CARBOHYDRATE DEGRADING POLYPEPTIDE AND APPLICATIONS THEREOF
MX2015010078A (es) 2013-02-06 2016-01-25 Novozymes As Uso de polipeptidos con actividad proteasa en alimentos para animales.
WO2014138672A1 (en) 2013-03-08 2014-09-12 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
ES2676895T5 (es) 2013-03-11 2022-04-27 Danisco Us Inc Variantes combinatorias de alfa-amilasa
ES2762154T3 (es) 2013-03-15 2020-05-22 Dsm Ip Assets Bv Uso de nucleasas termófilas para degradar ácidos nucleicos
WO2014145768A2 (en) 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi
US9631164B2 (en) 2013-03-21 2017-04-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP2976423B1 (en) 2013-03-21 2018-11-28 Novozymes A/S Polypeptides having phospholipase a activity and polynucleotides encoding same
US20160060660A1 (en) 2013-04-05 2016-03-03 Université Du Luxembourg Biotechnological production of itaconic acid
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2014170218A1 (en) 2013-04-18 2014-10-23 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2014177546A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP2994529B1 (en) 2013-05-10 2018-11-21 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
BR112015028666B8 (pt) 2013-05-14 2022-08-09 Novozymes As Composição detergente, método para produzir a mesma, método para a limpeza de um objeto e usos da composição
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
WO2014194032A1 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
EP3636662B1 (en) 2013-05-29 2022-07-13 Danisco US Inc. Novel metalloproteases
EP3004342B1 (en) 2013-05-29 2023-01-11 Danisco US Inc. Novel metalloproteases
EP3004341B1 (en) 2013-05-29 2017-08-30 Danisco US Inc. Novel metalloproteases
EP3004315A2 (en) 2013-06-06 2016-04-13 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2014200658A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from promicromonospora vindobonensis
WO2014200657A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces xiamenensis
WO2014200656A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces umbrinus
EP3011020A1 (en) 2013-06-17 2016-04-27 Danisco US Inc. Alpha-amylase from bacillaceae family member
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
BR112015032613B1 (pt) 2013-07-03 2020-11-24 Basf Se Uso de uma composiçao de polimero na forma de gel, e, metodo para limpeza de louqa em maquina
CN105358670A (zh) 2013-07-04 2016-02-24 诺维信公司 具有抗再沉积效果的具黄原胶裂解酶活性的多肽与编码它们的多核苷酸
WO2015004102A1 (en) 2013-07-09 2015-01-15 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CA2915336C (en) 2013-07-17 2024-03-12 Novozymes A/S Pullulanase chimeras and polynucleotides encoding same
US11981942B2 (en) 2013-07-23 2024-05-14 International N&H Denmark Aps Xylanases for solubilizing arabinoxylan-containing material
TWI667255B (zh) 2013-08-14 2019-08-01 美商生物化學醫療公司 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途
US10010094B2 (en) 2013-08-15 2018-07-03 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
BR112016005286A2 (pt) 2013-09-12 2017-09-12 Danisco Us Inc composições e métodos compreendendo variantes de protease do clado lg12
EP3052622B1 (en) 2013-10-03 2018-09-19 Danisco US Inc. Alpha-amylases from a subset of exiguobacterium, and methods of use, thereof
WO2015050723A1 (en) 2013-10-03 2015-04-09 Danisco Us Inc. Alpha-amylases from exiguobacterium, and methods of use, thereof
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
CN111851077A (zh) 2013-10-25 2020-10-30 诺维信公司 具有内切葡聚糖酶活性的多肽以及对其进行编码的多核苷酸
BR112016009365A2 (pt) 2013-10-28 2017-09-19 Danisco Us Inc Método para aumentar, melhorar e estender a produção de etanol e método para diminuir as concentrações finais de dp2 em um produto de fermentação
WO2015066669A1 (en) 2013-11-04 2015-05-07 Danisco Us Inc. Proteases in corn processing
WO2015066667A1 (en) 2013-11-04 2015-05-07 Danisco Us Inc. Proteases in wheat processing
MX2016006489A (es) 2013-11-20 2016-08-03 Danisco Us Inc Alfa-amilasas variantes que tienen susceptibilidad reducida a la escision por proteasas y metodos de uso.
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
WO2015081139A1 (en) 2013-11-26 2015-06-04 Novozymes A/S Enzyme compositions and uses thereof
EP3074509B1 (en) 2013-11-29 2019-03-06 Novozymes A/S Peroxygenase variants
US10487125B2 (en) 2013-12-02 2019-11-26 Dsm Ip Assets B.V. Ice structuring protein
US20160298157A1 (en) 2013-12-04 2016-10-13 Danisco Us Inc. Compositions comprising a beta-glucosidase polypeptide and methods of use
WO2015085920A1 (en) 2013-12-11 2015-06-18 Novozymes A/S Cutinase variants and polynucleotides encoding same
DK3080262T3 (da) 2013-12-13 2019-05-06 Danisco Us Inc Serinproteaser af bacillus-arter
DK3553173T3 (da) 2013-12-13 2021-08-23 Danisco Us Inc Serinproteaser af bacillus gibsonii-clade
EP2886656A1 (en) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof
WO2015094809A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Chimeric fungal alpha-amylases comprising carbohydrate binding module and the use thereof
WO2015094714A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Proteases in grain processing
CA2934039A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Use of hydrophobins to increase gas transferin aerobic fermentation processes
US10030239B2 (en) 2013-12-20 2018-07-24 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
DK3097192T3 (en) 2014-01-22 2018-11-19 Novozymes As PULLULANASE VARIATIONS AND POLYNUCLEOTIDES CODING THEM
US10208297B2 (en) 2014-01-22 2019-02-19 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same for cleaning
EP3099792B1 (en) 2014-01-31 2018-10-17 Danisco US Inc. Methods for improving by-products from fermentation processes using xylanase
GB201401648D0 (en) 2014-01-31 2014-03-19 Dupont Nutrition Biosci Aps Protein
US20170006902A1 (en) 2014-02-13 2017-01-12 Danisco Us Inc. Strategy for sucrose reduction and generation of insoluble fiber in juices
US20170027167A1 (en) 2014-03-05 2017-02-02 Novozymes Bioag A/S Formulations comprising polymeric xyloglucan as a carrier for agriculturally beneficial agents
WO2015134729A1 (en) 2014-03-05 2015-09-11 Novozymes A/S Compositions and methods for improving properties of non-cellulosic textile materials with xyloglucan endotransglycosylase
US20160333292A1 (en) 2014-03-05 2016-11-17 Novozymes A/S Compositions and Methods for Improving Properties of Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
CN106068077B (zh) 2014-03-05 2019-06-07 诺维信公司 用于改进农作物的收获后特性的组合物和方法
US20170073890A1 (en) 2014-03-05 2017-03-16 Novozymes A/S Compositions and Methods for Functionalizing and Linking Materials
CN111500552A (zh) 2014-03-12 2020-08-07 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
MX2016012044A (es) 2014-03-21 2017-06-29 Danisco Us Inc Serina proteasas de especies de bacillus.
CN106103708A (zh) 2014-04-01 2016-11-09 诺维信公司 具有α淀粉酶活性的多肽
EP3129478B1 (en) 2014-04-10 2019-03-27 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US9901706B2 (en) 2014-04-11 2018-02-27 Boston Scientific Scimed, Inc. Catheters and catheter shafts
EP3406697B1 (en) 2014-04-11 2020-06-10 Novozymes A/S Detergent composition
WO2015158237A1 (en) 2014-04-15 2015-10-22 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015181119A2 (en) 2014-05-27 2015-12-03 Novozymes A/S Lipase variants and polynucleotides encoding same
CN106459937B (zh) 2014-05-27 2024-09-10 诺维信公司 用于产生脂肪酶的方法
US10385326B2 (en) 2014-05-30 2019-08-20 Novozymes A/S Variants of GH family 11 xylanase and polynucleotides encoding same
EP3152315B1 (en) 2014-06-06 2018-08-15 Novozymes A/S Enzyme compositions and uses thereof
ES2712402T3 (es) 2014-06-25 2019-05-13 Novozymes As Variantes de xilanasa y polinucleótidos que las codifican
US20170267980A1 (en) 2014-08-20 2017-09-21 Novozymes A/S Xyloglucan Endotransglycosylase variants and Polynucleotides Encoding Same
CN107002056A (zh) 2014-09-05 2017-08-01 诺维信公司 碳水化合物结合模块变体以及编码它们的多核苷酸
US20170226494A1 (en) 2014-09-30 2017-08-10 Danisco Us Inc. Compositions comprising beta-mannanase and methods of use
US20170211053A1 (en) 2014-09-30 2017-07-27 Danisco Us Inc. Compositions comprising beta mannanase and methods of use
EP3201330A1 (en) 2014-09-30 2017-08-09 Danisco US Inc. Compositions comprising beta mannanase and methods of use
US20170218351A1 (en) 2014-09-30 2017-08-03 Danisco Us Inc. Compositions comprising beta-mannanase and methods of use
WO2016054194A1 (en) 2014-09-30 2016-04-07 1/1Danisco Us Inc Compositions comprising beta-mannanase and methods of use
EP3207129B1 (en) 2014-10-17 2019-11-20 Danisco US Inc. Serine proteases of bacillus species
US10584324B2 (en) 2014-10-23 2020-03-10 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CN107105709B (zh) 2014-10-24 2021-04-30 杜邦营养生物科学有限公司 脯氨酸耐受性三肽基肽酶在饲料添加剂组合物中的用途
WO2016065238A1 (en) 2014-10-24 2016-04-28 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
US20170335306A1 (en) 2014-10-27 2017-11-23 Danisco Us Inc. Serine proteases
EP3224357A1 (en) 2014-10-27 2017-10-04 Danisco US Inc. Serine proteases of bacillus species
DK3212776T3 (da) 2014-10-27 2020-08-03 Danisco Us Inc Sammensætninger og fremgangsmåder i forbindelse med beta-glucosidase
WO2016069552A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
EP3212783B1 (en) 2014-10-27 2024-06-26 Danisco US Inc. Serine proteases
EP3550017B1 (en) 2014-10-27 2021-07-14 Danisco US Inc. Serine proteases
US10287562B2 (en) 2014-11-20 2019-05-14 Novoszymes A/S Alicyclobacillus variants and polynucleotides encoding same
US10781428B2 (en) 2014-12-02 2020-09-22 Novozymes A/S Laccase variants and polynucleotides encoding same
MX2017007103A (es) 2014-12-05 2017-08-24 Novozymes As Variantes de lipasa y polinucleotidos que las codifican.
CN107002049A (zh) 2014-12-16 2017-08-01 诺维信公司 具有n‑乙酰基葡萄糖胺氧化酶活性的多肽
EP3234119A1 (en) 2014-12-18 2017-10-25 Danisco US Inc. Engineered multifunctional enzymes and methods of use
AU2015366380B2 (en) 2014-12-19 2021-07-22 Novozymes A/S Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
WO2016102951A1 (en) 2014-12-23 2016-06-30 4D Pharma Research Limited Pirin polypeptide and immune modulation
ME02997B (me) 2014-12-23 2018-10-20 4D Pharma Res Ltd Soj bacteroides thetaiotaomicron i njegova upotreba u smanjenju inflamacije
WO2016110453A1 (en) 2015-01-06 2016-07-14 Dsm Ip Assets B.V. A crispr-cas system for a filamentous fungal host cell
US20180028454A1 (en) 2015-02-04 2018-02-01 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
EP3262165B1 (en) 2015-02-24 2020-06-03 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
US10385352B2 (en) 2015-03-09 2019-08-20 Novozymes A/S Methods of introducing multiple expression constructs into a eukaryotic cell
EP3268471B1 (en) 2015-03-12 2019-08-28 Danisco US Inc. Compositions and methods comprising lg12-clade protease variants
WO2016164583A2 (en) 2015-04-07 2016-10-13 Novozymes A/S Methods for selecting enzymes having enhanced activity
US20180355404A1 (en) 2015-04-07 2018-12-13 Novozymes A/S Methods for selecting enzymes having lipase activity
WO2016183509A1 (en) 2015-05-13 2016-11-17 Danisco Us Inc. AprL-CLADE PROTEASE VARIANTS AND USES THEREOF
US9920102B2 (en) 2015-05-15 2018-03-20 Albert Einstein College Of Medicine, Inc. Fusion tags for protein expression
EP3298138B1 (en) 2015-05-22 2022-08-10 DuPont Nutrition Biosciences ApS Acetolactate decarboxylase
US10519520B2 (en) 2015-05-27 2019-12-31 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
AU2016273208B2 (en) 2015-06-02 2021-01-21 Dsm Ip Assets B.V. Use of ice structuring protein AFP19 expressed in filamentous fungal strains for preparing food
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
PL3206700T3 (pl) 2015-06-15 2019-11-29 4D Pharma Res Ltd Kompozycje zawierające szczepy bakteryjne
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN115364122A (zh) 2015-06-15 2022-11-22 4D制药研究有限公司 包含细菌菌株的组合物
MD3307288T2 (ro) 2015-06-15 2019-12-31 4D Pharma Res Ltd Compoziții care conțin tulpini bacteriene
US10858637B2 (en) 2015-06-16 2020-12-08 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
US11499146B2 (en) 2015-06-17 2022-11-15 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
CN108350442A (zh) 2015-06-18 2018-07-31 诺维信公司 具有海藻糖酶活性的多肽及其在产生发酵产物的方法中的用途
BR112017028063B1 (pt) 2015-06-26 2022-05-17 Novozymes A/S Método para produção de um extrato de café
WO2016210395A1 (en) 2015-06-26 2016-12-29 Dupont Nutrition Biosciences Aps Aminopeptidases for protein hydrlyzates
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
EP3313990A4 (en) 2015-06-26 2019-01-23 Novozymes A/S BIOLOGICAL FINISHING TREATMENT SYSTEM
CA2987160C (en) 2015-07-01 2022-12-13 Novozymes A/S Methods of reducing odor
US10945449B2 (en) 2015-07-02 2021-03-16 Novozymes A/S Animal feed compositions and uses thereof
EP4032409A1 (en) 2015-07-02 2022-07-27 Novozymes A/S Animal feed comprising a feed additive for improving animal performance
WO2017005816A1 (en) 2015-07-06 2017-01-12 Novozymes A/S Lipase variants and polynucleotides encoding same
JP6709590B2 (ja) 2015-07-16 2020-06-17 本田技研工業株式会社 タンパク質生産用システム及びタンパク質の製造方法
JP6709591B2 (ja) * 2015-07-16 2020-06-17 本田技研工業株式会社 タンパク質生産用システム及びタンパク質の製造方法
WO2017010107A1 (en) * 2015-07-16 2017-01-19 Honda Motor Co., Ltd. Base sequence for protein expression and method for producing protein using same
US20180216089A1 (en) 2015-07-24 2018-08-02 Novozymes, Inc. Polypeptides Having Beta-Xylosidase Activity And Polynucleotides Encoding Same
WO2017019490A1 (en) 2015-07-24 2017-02-02 Novozymes Inc. Polypeptides having arabinofuranosidase activity and polynucleotides encoding same
UA126016C2 (uk) 2015-08-03 2022-08-03 Біовератів Терапеутікс Інк. Злитий білок фактора іх
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
EP3344282B8 (en) 2015-09-02 2020-12-23 DuPont Nutrition Biosciences ApS Glycoside hydrolases and their use in preventing and/or treating a pathogenic infection in an animal
WO2017040907A1 (en) 2015-09-04 2017-03-09 Novozymes A/S Methods of inhibiting aa9 lytic polysaccharide monooxygenase catalyzed inactivation of enzyme compositions
WO2017046260A1 (en) 2015-09-17 2017-03-23 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
EP3353195B1 (en) 2015-09-22 2021-11-10 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
EP3359658A2 (en) 2015-10-07 2018-08-15 Novozymes A/S Polypeptides
CN108291212A (zh) 2015-10-14 2018-07-17 诺维信公司 多肽变体
US20180171318A1 (en) 2015-10-14 2018-06-21 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
EP3368674A1 (en) 2015-10-30 2018-09-05 Novozymes A/S Polynucleotide constructs for in vitro and in vivo expression
WO2017079756A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus and bacillus spp. mannanases
EP4141113A1 (en) 2015-11-05 2023-03-01 Danisco US Inc Paenibacillus sp. mannanases
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EA034677B1 (ru) 2015-11-20 2020-03-05 4Д Фарма Рисёрч Лимитед Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EP3380608A1 (en) 2015-11-24 2018-10-03 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2017093318A1 (en) 2015-12-01 2017-06-08 Novozymes A/S Methods for producing lipases
US10981957B2 (en) 2015-12-02 2021-04-20 Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement Peptides having antimicrobial activity and new enzyme capable of converting L-configured residue in D-configured amino acid in a peptide
KR20190090081A (ko) 2015-12-07 2019-07-31 지머젠 인코포레이티드 Htp 게놈 공학 플랫폼에 의한 미생물 균주 개량
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CA3007635A1 (en) 2015-12-07 2017-06-15 Zymergen Inc. Promoters from corynebacterium glutamicum
EP3390625B1 (en) 2015-12-18 2023-09-06 Danisco US Inc. Polypeptides with endoglucanase activity and uses thereof
EP4219702A3 (en) 2015-12-30 2023-11-01 Novozymes A/S Enzyme variants and polynucleotides encoding the same
WO2017129754A1 (en) 2016-01-29 2017-08-03 Novozymes A/S Beta-glucanase variants and polynucleotides encoding same
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
EP3420104A1 (en) 2016-02-23 2019-01-02 Novozymes A/S Improved next-generation sequencing
EP4410974A2 (en) 2016-03-02 2024-08-07 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
DK3313423T3 (da) 2016-03-04 2019-05-20 4D Pharma Plc Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
DK3433358T3 (da) 2016-03-24 2022-09-26 Novozymes As Cellobiohydrolasevarianter og polynukleotider, der koder for dem
WO2017173190A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
WO2017173324A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
US20190161786A1 (en) 2016-04-07 2019-05-30 Novozymes A/S Methods for selecting enzymes having protease activity
EP3445776B1 (en) 2016-04-19 2021-02-17 Novozymes A/S Rlma-inactivated filamentous fungal host cell
BR112018072282A2 (pt) 2016-04-29 2019-02-12 Novozymes A/S composições detergentes e usos das mesmas
JP2019518440A (ja) 2016-05-03 2019-07-04 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
EP3452497B1 (en) 2016-05-03 2021-02-17 Novozymes A/S Alpha-amylase variants and polynucleotides encoding the same
WO2017192300A1 (en) 2016-05-05 2017-11-09 Danisco Us Inc Protease variants and uses thereof
JP6985295B2 (ja) 2016-05-09 2021-12-22 ノボザイムス アクティーゼルスカブ 向上した性能を有する変異体ポリペプチドおよびその使用
EP3246401A1 (en) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives New fatty acid decarboxylase and its uses
MX2018014234A (es) 2016-05-24 2019-03-28 Novozymes As Polipeptidos que tienen actividad alfa-galactosidasa y polinucleotidos que los codifican.
AU2017270231A1 (en) 2016-05-24 2018-11-15 Novozymes A/S Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity
BR112018073283A2 (pt) 2016-05-24 2019-03-19 Novozymes A/S composição, grânulo, aditivo de ração para animal, ração para animal, ração para animal peletizada, formulação líquida, método para liberar galactose do material à base de planta, método para melhorar um ou mais parâmetros de desempenho de um animal, uso da composição, do grânulo, do aditivo de ração para animal ou da formulação líquida, polipeptídeo isolado, método para produzir o polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira
WO2017202979A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
CN109477112B (zh) 2016-05-31 2024-09-06 丹尼斯科美国公司 蛋白酶变体及其用途
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
JP7152319B2 (ja) 2016-06-17 2022-10-12 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
US10421951B2 (en) 2016-06-22 2019-09-24 Wisconsin Alumni Research Foundation Gene construct encoding mutant thioesterase, mutant thioesterase encoded thereby, transformed host cell containing the gene construct, and method of using them to produce medium-chain fatty acids
KR102345898B1 (ko) 2016-06-30 2022-01-03 지머젠 인코포레이티드 글루코오스 투과 효소 라이브러리를 생성하는 방법 및 이의 용도
WO2018005655A2 (en) 2016-06-30 2018-01-04 Zymergen Inc. Methods for generating a bacterial hemoglobin library and uses thereof
ES2807212T3 (es) 2016-06-30 2021-02-22 Fornia Biosolutions Inc Nuevas fitasas y usos de las mismas
CN109642226A (zh) 2016-06-30 2019-04-16 丹尼斯科美国公司 天冬氨酸蛋白酶
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
EP3481949B1 (en) 2016-07-05 2021-06-09 Novozymes A/S Pectate lyase variants and polynucleotides encoding same
CN109312353A (zh) 2016-07-06 2019-02-05 诺维信公司 通过crispr-抑制来改善微生物
CN109415749A (zh) 2016-07-07 2019-03-01 诺维信公司 在木霉属中生产发酵产物的方法
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
EP3481948B1 (en) 2016-07-08 2023-11-01 Novozymes A/S Xylanase variants and polynucleotides encoding same
CN109415709A (zh) 2016-07-08 2019-03-01 诺维信公司 具有木聚糖酶活性的多肽以及编码其的多核苷酸
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
JP6858850B2 (ja) 2016-07-13 2021-04-14 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ バチルス・シビ（ＢＡＣＩＬＬＵＳ ＣＩＢＩ）ＤＮａｓｅ変異体及びその使用
EP4357453A2 (en) 2016-07-18 2024-04-24 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
WO2018017792A1 (en) 2016-07-20 2018-01-25 Novozymes A/S Heat-stable metagenomic carbonic anhydrases and their use
ES2884155T3 (es) 2016-07-21 2021-12-10 Novozymes As Variantes de serina proteasa y polinucleótidos que codifican las mismas
ES2981748T3 (es) 2016-07-21 2024-10-10 Novozymes As Variantes de serina proteasa y polinucleótidos que las codifican
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
CN109476714A (zh) 2016-07-22 2019-03-15 诺维信公司 改善的丝状真菌宿主
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2018037062A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
CN109563451A (zh) 2016-08-24 2019-04-02 汉高股份有限及两合公司 包含gh9内切葡聚糖酶变体i的洗涤剂组合物
US11512300B2 (en) 2016-08-24 2022-11-29 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
AU2017317563B8 (en) 2016-08-24 2023-03-23 Henkel Ag & Co. Kgaa Detergent compositions comprising xanthan lyase variants I
US20190225988A1 (en) 2016-09-15 2019-07-25 Novozymes A/S Genomic integration of DNA fragments in fungal host cells
CA3037083A1 (en) 2016-09-16 2018-03-22 Dupont Nutrition Biosciences Aps Acetolactate decarboxylase variants having improved specific activity
RU2763378C2 (ru) 2016-09-23 2021-12-28 ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС ПРИМЕНЕНИЕ АКТИВНЫХ ПРИ НИЗКОМ ЗНАЧЕНИИ pH АЛЬФА-1,4/1,6-ГЛИКОЗИДГИДРОЛАЗ В КАЧЕСТВЕ КОРМОВОЙ ДОБАВКИ ДЛЯ ЖВАЧНЫХ ЖИВОТНЫХ ДЛЯ УЛУЧШЕНИЯ ПЕРЕВАРИВАНИЯ КРАХМАЛА
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
EP3535365A2 (en) 2016-11-07 2019-09-11 Danisco US Inc. Laundry detergent composition
CN110100011A (zh) 2016-11-21 2019-08-06 诺维信公司 Dna分子的酵母细胞提取物辅助构建
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US20200392477A1 (en) 2016-12-21 2020-12-17 Danisco Us Inc. Protease variants and uses thereof
US11946081B2 (en) 2016-12-21 2024-04-02 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
EP3558026A1 (en) 2016-12-21 2019-10-30 DuPont Nutrition Biosciences ApS Methods of using thermostable serine proteases
EP3565582B1 (en) 2017-01-04 2022-03-09 Novozymes A/S Microbial lysozyme for use in the treatment of irritable bowel syndrome or inflammatory bowel disease
CN106754838B (zh) * 2017-01-20 2020-06-09 上海绿农饲料科技有限公司 一种提高黑曲霉产蛋白酶能力的方法
MX2019008967A (es) 2017-02-01 2019-09-10 Novozymes As Variantes de alfa-amilasas.
CA3051426C (en) 2017-02-01 2023-10-17 The Procter & Gamble Company Cleaning compositions comprising amylase variants
MX2019009551A (es) 2017-02-20 2020-01-30 Novozymes As Enzima lipolitica para usarse en horneado.
BR112019018381A2 (pt) 2017-03-06 2020-04-07 Dupont Nutrition Biosci Aps fucosidases fúngicas e seu uso na prevenção e/ou no tratamento de uma infecção patogênica em um animal
WO2018166943A1 (en) 2017-03-13 2018-09-20 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
WO2018169780A1 (en) 2017-03-15 2018-09-20 Dupont Nutrition Biosciences Aps Methods of using an archaeal serine protease
CN110621778A (zh) 2017-03-15 2019-12-27 丹尼斯科美国公司 胰蛋白酶样丝氨酸蛋白酶及其用途
CN110621777A (zh) 2017-03-15 2019-12-27 杜邦营养生物科学有限公司 胰蛋白酶样丝氨酸蛋白酶及其用途
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
WO2018172155A1 (en) 2017-03-23 2018-09-27 Novozymes A/S Improved filamentous fungal host cells
CN107353327A (zh) 2017-03-30 2017-11-17 南京百斯杰生物工程有限公司 植酸酶在黑曲霉中表达
US11053483B2 (en) 2017-03-31 2021-07-06 Novozymes A/S Polypeptides having DNase activity
US11208639B2 (en) 2017-03-31 2021-12-28 Novozymes A/S Polypeptides having DNase activity
EP3601551A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having rnase activity
US20200109388A1 (en) 2017-04-03 2020-04-09 Novozymes A/S Recovery Process
EP3607039A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Polypeptides
CN114480034A (zh) 2017-04-04 2022-05-13 诺维信公司 糖基水解酶
US20200109352A1 (en) 2017-04-04 2020-04-09 Novozymes A/S Polypeptide compositions and uses thereof
EP3619304A1 (en) 2017-05-05 2020-03-11 Novozymes A/S Compositions comprising lipase and sulfite
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
US12018235B2 (en) 2017-05-08 2024-06-25 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206300A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
LT3630136T (lt) 2017-05-22 2021-06-10 4D Pharma Research Limited Kompozicijos, apimančios bakterines padermes
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
CN110869502A (zh) 2017-06-06 2020-03-06 齐默尔根公司 高通量转座子诱变
EP3635110A2 (en) 2017-06-06 2020-04-15 Zymergen, Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa
WO2018226900A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A htp genomic engineering platform for improving fungal strains
IL283973B (en) 2017-06-14 2022-08-01 4D Pharma Res Ltd Preparations containing bacterial strains
EP3638271B1 (en) 2017-06-14 2020-10-14 4D Pharma Research Limited Compositions comprising bacterial strains
HUE052258T2 (hu) 2017-06-14 2021-04-28 4D Pharma Res Ltd Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása
WO2018234465A1 (en) 2017-06-22 2018-12-27 Novozymes A/S XYLANASE VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME
EP4015524A1 (en) 2017-06-28 2022-06-22 Novozymes A/S Polypeptides having trehalase activity and polynucleotides encoding same
EP3645696A1 (en) 2017-06-30 2020-05-06 Danisco US Inc. Low-agglomeration, enzyme-containing particles
HUE064842T2 (hu) 2017-07-24 2024-04-28 Novozymes As GH5 és GH30 nedves õrlésben
US10081800B1 (en) 2017-08-03 2018-09-25 Fornia Biosolutions, Inc. Lactonase enzymes and methods of using same
US11220679B2 (en) 2017-08-08 2022-01-11 Novozymes A/S Polypeptides having trehalase activity
CN111344404A (zh) 2017-08-24 2020-06-26 诺维信公司 黄原胶裂解酶变体以及编码其的多核苷酸
US11624059B2 (en) 2017-08-24 2023-04-11 Henkel Ag & Co. Kgaa Detergent compositions comprising GH9 endoglucanase variants II
WO2019038060A1 (en) 2017-08-24 2019-02-28 Henkel Ag & Co. Kgaa DETERGENT COMPOSITION COMPRISING XANTHANE LYASE II VARIANTS
CA3070749A1 (en) 2017-08-24 2019-02-28 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
CN111050565A (zh) 2017-09-01 2020-04-21 诺维信公司 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途
EP3675647B1 (en) 2017-09-01 2024-10-09 Novozymes A/S Animal feed additives comprising a polypeptide having protease activity and uses thereof
US20200216787A1 (en) 2017-09-18 2020-07-09 Dupont Nutrition Biosciences Aps Riboflavinase enzymes and their use to prevent off flavor in brewing
CN111356762B (zh) 2017-09-27 2024-09-17 诺维信公司 脂肪酶变体和包含此类脂肪酶变体的微囊组合物
US11286443B2 (en) 2017-09-27 2022-03-29 The Procter & Gamble Company Detergent compositions comprising lipases
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
BR112020006621A2 (pt) 2017-10-02 2020-10-06 Novozymes A/S polipeptídeos com atividade de mananase e polinucleotídeos codificando os mesmos
JPWO2019069977A1 (ja) * 2017-10-03 2020-12-24 キッコーマン株式会社 アルカリホスファターゼの製造方法及びそれを用いて得られるアルカリホスファターゼ、並びにその製造のためのベクター及び形質転換体
BR112020008251A2 (pt) 2017-10-27 2020-11-17 Novozymes A/S variantes de dnase
CN111247245A (zh) 2017-10-27 2020-06-05 宝洁公司 包含多肽变体的洗涤剂组合物
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
CN111511908A (zh) 2017-11-10 2020-08-07 诺维信公司 温度敏感性cas9蛋白
BR112020009525A2 (pt) 2017-11-14 2020-11-03 Danisco Us Inc. alfa-amilase, composição e método
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
CN111373039A (zh) 2017-11-29 2020-07-03 丹尼斯科美国公司 具有改善的稳定性的枯草杆菌蛋白酶变体
CN111670248A (zh) 2017-12-04 2020-09-15 诺维信公司 脂肪酶变体以及编码其的多核苷酸
BR112020012431A2 (pt) 2017-12-19 2020-11-24 Dupont Nutrition Biosciences Aps modificação enzimática melhorada de fosfolipídios em alimento
US11696596B2 (en) 2017-12-20 2023-07-11 Societe Des Produits Nestle S.A. Process for the preparation of pickering emulsion forming particles by derivatization of cellulose-rich dietary fibers with enzymes and emulsions prepared
BR112020012584A2 (pt) 2017-12-21 2020-11-24 Danisco Us Inc. grânulos fundidos a quente contendo enzima que compreendem um dessecante termotolerante
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
BR112020016068A2 (pt) 2018-02-08 2020-12-08 Danisco Us Inc. Partículas cera termicamente resistente matriz para encapsulamento de enzima
CN111868239A (zh) 2018-02-08 2020-10-30 诺维信公司 脂肪酶、脂肪酶变体及其组合物
EP3749758A1 (en) 2018-02-08 2020-12-16 Novozymes A/S Lipase variants and compositions thereof
EP3530744A1 (en) 2018-02-23 2019-08-28 University of Limerick A polypeptide having xylanase and/or cellulase activity
US20230272353A1 (en) 2018-02-23 2023-08-31 Novozymes A/S Long Non-Coding RNA-Expression In Fungal Hosts
DK3775222T5 (da) 2018-03-26 2024-08-19 Novozymes As Chaperoneproteiner fra svampe
US11535837B2 (en) 2018-03-29 2022-12-27 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2019197318A1 (en) 2018-04-09 2019-10-17 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CN112272701B (zh) 2018-04-19 2024-05-14 诺维信公司 稳定化的纤维素酶变体
EP3781680A1 (en) 2018-04-19 2021-02-24 Novozymes A/S Stabilized cellulase variants
TW202015723A (zh) 2018-05-18 2020-05-01 美商百歐維拉提夫治療公司 治療ａ型血友病的方法
KR20210018219A (ko) 2018-06-06 2021-02-17 지머젠 인코포레이티드 발효 및 생산 중 곰팡이 형태를 제어하기 위한 신호 전달에 포함된 유전자의 조작
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US20210363470A1 (en) 2018-06-19 2021-11-25 Danisco Us Inc Subtilisin variants
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
EP3818154A1 (en) 2018-07-06 2021-05-12 DuPont Nutrition Biosciences ApS Xylanase-containing feed additives for cereal-based animal feed
CN112789504A (zh) 2018-07-13 2021-05-11 瓦克特诊断有限责任公司 使用重组疟疾蛋白var2csa分离胎儿来源的循环细胞
US20210315238A1 (en) 2018-07-31 2021-10-14 Dupont Nutrition Biosciences Aps Proline specific endopeptidases
US20210301285A1 (en) 2018-08-02 2021-09-30 Novozymes A/S Preparation of Combinatorial Libraries of DNA Constructs
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
BR112021003244A2 (pt) 2018-08-31 2021-05-18 Novozymes A/S polipeptídeo isolado ou purificado, uso, método para melhoria do valor nutricional de uma ração animal, aditivo de ração animal, ração animal, polinucleotídeo isolado ou purificado, construção de ácido nucleico ou vetor de expressão, e, célula hospedeira recombinante
EP3849338A2 (en) 2018-09-11 2021-07-21 DSM IP Assets B.V. Animal feed composition comprising muramidase and use thereof
AU2019338224A1 (en) 2018-09-11 2021-03-04 Dsm Ip Assets B.V. Animal feed composition and use thereof
WO2020053273A1 (en) 2018-09-11 2020-03-19 Dsm Ip Assets B.V. Animal feed composition and use thereof
WO2020053276A1 (en) 2018-09-11 2020-03-19 Dsm Ip Assets B.V. Animal feed composition and use thereof
CN112804883A (zh) 2018-09-11 2021-05-14 帝斯曼知识产权资产管理有限公司 动物饲料组合物及其用途
WO2020068486A1 (en) 2018-09-27 2020-04-02 Danisco Us Inc Compositions for medical instrument cleaning
WO2020070199A1 (en) 2018-10-03 2020-04-09 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
WO2020074502A1 (en) 2018-10-09 2020-04-16 Novozymes A/S Modified filamentous fungal host cell
EP3874051A1 (en) 2018-10-31 2021-09-08 Novozymes A/S Genome editing by guided endonuclease and single-stranded oligonucleotide
WO2020099491A1 (en) 2018-11-14 2020-05-22 Novozymes A/S Oral care composition comprising a polypeptide having dnase activity
WO2020106796A1 (en) 2018-11-20 2020-05-28 Dupont Nutrition Biosciences Aps ENGINEERED ROBUST HIGH Tm-PHYTASE CLADE POLYPEPTIDES AND FRAGMENTS THEREOF
EP3887524A1 (en) 2018-11-28 2021-10-06 Novozymes A/S Modified filamentous fungal host cells
EP3887391A1 (en) 2018-11-28 2021-10-06 Novozymes A/S Improved filamentous fungal host cells
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
US20220064228A1 (en) 2018-12-12 2022-03-03 Novozymes A/S Methods For Increasing The Productivity Of A Filamentous Fungal Cell In The Production Of A Polypeptide
US20220025348A1 (en) 2018-12-12 2022-01-27 Novozymes A/S Polypeptides Having Xylanase Activity And Polynucleotides Encoding Same
DK3898985T5 (da) 2018-12-21 2024-08-05 Novozymes As Proteinekspression i tandem
CN113366103A (zh) 2018-12-21 2021-09-07 诺维信公司 具有肽聚糖降解活性的多肽以及编码其的多核苷酸
CN113646428A (zh) 2019-02-25 2021-11-12 杜邦营养生物科学有限公司 具有增加的n-末端氨基酸产率的蛋白质水解产物
WO2020173817A1 (en) 2019-02-28 2020-09-03 Novozymes A/S Calcite binding proteins
US20220154226A1 (en) 2019-03-18 2022-05-19 Novozymes A/S Polypeptides Having Pullulanase Activity Suitable For Use In Liquefaction
US10995325B2 (en) 2019-03-21 2021-05-04 Fornia Biosolutions, Inc. Additional phytase variants and methods
JP2020162549A (ja) 2019-03-29 2020-10-08 味の素株式会社 制御装置、制御方法およびプログラムならびに有機化合物の製造方法
MX2021011981A (es) 2019-04-03 2021-11-03 Novozymes As Polipeptidos que tienen actividad de beta-glucanasa, polinucleotidos que los codifican y usos de los mismos en composiciones de limpieza y de detergente.
WO2020207944A1 (en) 2019-04-10 2020-10-15 Novozymes A/S Polypeptide variants
US20220186151A1 (en) 2019-04-12 2022-06-16 Novozymes A/S Stabilized glycoside hydrolase variants
US20220275354A1 (en) 2019-05-15 2022-09-01 Novozymes A/S TEMPERATURE-SENSITIVE RNA- Guided Endonuclease
EP3976776A1 (en) 2019-05-24 2022-04-06 Danisco US Inc. Subtilisin variants and methods of use
WO2020247582A1 (en) 2019-06-06 2020-12-10 Danisco Us Inc Methods and compositions for cleaning
US20220306791A1 (en) 2019-06-14 2022-09-29 Basf Se Aqueous polymer dispersions suitable as opacifiers in liquid formulations
CN113993996A (zh) 2019-06-24 2022-01-28 诺维信公司 α-淀粉酶变体
EP3986996A1 (en) 2019-06-24 2022-04-27 The Procter & Gamble Company Cleaning compositions comprising amylase variants
CN114207125A (zh) 2019-06-25 2022-03-18 诺维信公司 通过抑制条件性必需基因进行反向选择
EP3994255A1 (en) 2019-07-02 2022-05-11 Novozymes A/S Lipase variants and compositions thereof
EP4004211A1 (en) 2019-07-25 2022-06-01 Novozymes A/S Filamentous fungal expression system
US20220251581A1 (en) 2019-07-26 2022-08-11 Novozymes A/S Modified filamentous fungal host cell
MX2022002834A (es) 2019-09-16 2022-04-06 Novozymes As Polipeptidos con actividad beta-glucanasa y polinucleotidos que los codifican.
US20220340843A1 (en) 2019-10-03 2022-10-27 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
US20220389458A1 (en) 2019-11-04 2022-12-08 Dsm Ip Assets B.V. Low volume transfection
US20230009832A1 (en) 2019-11-20 2023-01-12 Dupont Nutrition Biosciences Aps Thermostable phytase variants
JP2023506284A (ja) 2019-12-19 2023-02-15 ビーエーエスエフ ソシエタス・ヨーロピア ファインケミカルを生成する際の空時収率、炭素変換効率、及び炭素基質適応性の増加
AR120801A1 (es) 2019-12-19 2022-03-16 Novozymes As Variantes de xilanasa y polinucleótidos que codifican las mismas
EP4076002A1 (en) 2019-12-19 2022-10-26 DuPont Nutrition Biosciences ApS Diet formulations
US20230041211A1 (en) 2019-12-20 2023-02-09 Basf Se Decreasing toxicity of terpenes and increasing the production potential in micro-organisms
EP4077656A2 (en) 2019-12-20 2022-10-26 Novozymes A/S Polypeptides having proteolytic activity and use thereof
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
CN115052981A (zh) 2020-01-31 2022-09-13 诺维信公司 甘露聚糖酶变体以及编码它们的多核苷酸
WO2021152120A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
US20240228996A1 (en) 2020-02-10 2024-07-11 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US20230142991A1 (en) 2020-02-10 2023-05-11 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2021163015A1 (en) 2020-02-10 2021-08-19 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
EP4110909A1 (en) 2020-02-26 2023-01-04 Novozymes A/S Polypeptide variants
US20230240334A1 (en) 2020-02-28 2023-08-03 Dupont Nutrition Biosciences Aps Feed compositions
CN115427560A (zh) 2020-03-12 2022-12-02 诺维信公司 使用无催化活性rna指导的内切核酸酶的crispr-aid
EP3892708A1 (en) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Cleaning compositions comprising dispersin variants
EP4133066A1 (en) 2020-04-08 2023-02-15 Novozymes A/S Carbohydrate binding module variants
EP4136459A1 (en) 2020-04-13 2023-02-22 Abbott Laboratories Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
US20230167384A1 (en) 2020-04-21 2023-06-01 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
EP4153765A1 (en) 2020-05-20 2023-03-29 Wisconsin Alumni Research Foundation Cells and methods for producing methyl ketones
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
US20220043000A1 (en) 2020-08-04 2022-02-10 Abbott Laboratories Methods and kits for detecting sars-cov-2 protein in a sample
CN116322625A (zh) 2020-08-24 2023-06-23 诺维信公司 包含果聚糖酶的口腔护理组合物
JP2023538740A (ja) 2020-08-25 2023-09-11 ノボザイムス アクティーゼルスカブ ファミリー４４キシログルカナーゼの変異体
CN116323935A (zh) 2020-08-27 2023-06-23 丹尼斯科美国公司 用于清洁的酶和酶组合物
JP2023538773A (ja) 2020-08-28 2023-09-11 ノボザイムス アクティーゼルスカブ 改善された溶解性を有するプロテアーゼバリアント
BR112023005131A2 (pt) 2020-09-21 2023-04-25 Dupont Nutrition Biosci Aps Processo para fazer um produto de panificação com resiliência melhorada, produto de panificação, uso de uma exoamilase não maltogênica e uma glucoamilase, composição melhoradora para uma massa e massa
CN116529375A (zh) 2020-10-13 2023-08-01 诺维信公司 用于提高蛋白质产量的糖基转移酶变体
CN116390651A (zh) 2020-10-15 2023-07-04 帝斯曼知识产权资产管理有限公司 调节胃肠道代谢物的方法
JP2023547450A (ja) 2020-10-29 2023-11-10 ノボザイムス アクティーゼルスカブ リパーゼ変異体及びそのようなリパーゼ変異体を含む組成物
AU2021370998A1 (en) 2020-11-02 2023-05-25 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP4237430A1 (en) 2020-11-02 2023-09-06 Novozymes A/S Leader peptides and polynucleotides encoding the same
EP4026900A3 (en) 2020-12-17 2022-10-05 Fornia BioSolutions, Inc. Xylanase variants and methods
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2023288294A1 (en) 2021-07-16 2023-01-19 Novozymes A/S Compositions and methods for improving the rainfastness of proteins on plant surfaces
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
WO2022147147A1 (en) 2020-12-30 2022-07-07 Abbott Laboratories Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
US20240117275A1 (en) 2021-01-29 2024-04-11 Danisco Us Inc. Compositions for cleaning and methods related thereto
WO2022175440A1 (en) 2021-02-18 2022-08-25 Novozymes A/S Inactive heme polypeptides
EP4305146A1 (en) 2021-03-12 2024-01-17 Novozymes A/S Polypeptide variants
CA3199985A1 (en) 2021-03-15 2022-09-22 Lars Lehmann Hylling Christensen Cleaning compositions containing polypeptide variants
WO2022194673A1 (en) 2021-03-15 2022-09-22 Novozymes A/S Dnase variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
CN116981365A (zh) 2021-03-16 2023-10-31 帝斯曼知识产权资产管理有限公司 动物饲料组合物及其用途
EP4071763A1 (en) 2021-04-08 2022-10-12 DuPont Nutrition Biosciences ApS A method for measuring galactooligosaccharides
WO2022251056A1 (en) 2021-05-27 2022-12-01 Novozymes A/S Transcriptional regulators and polynucleotides encoding the same
US20240228917A1 (en) 2021-06-18 2024-07-11 International N&H Denmark Aps Proteases for beer haze reduction
WO2022268885A1 (en) 2021-06-23 2022-12-29 Novozymes A/S Alpha-amylase polypeptides
WO2023278297A1 (en) 2021-06-30 2023-01-05 Danisco Us Inc Variant lipases and uses thereof
EP4402258A2 (en) 2021-09-13 2024-07-24 Danisco US Inc. Bioactive-containing granules
EP4448750A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and uses thereof
CN118679251A (zh) 2021-12-16 2024-09-20 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023152220A1 (en) 2022-02-10 2023-08-17 Novozymes A/S Improved expression of recombinant proteins
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
EP4242303A1 (en) 2022-03-08 2023-09-13 Novozymes A/S Fusion polypeptides with deamidase inhibitor and deamidase domains
AU2023231428A1 (en) 2022-03-08 2024-07-11 Novozymes A/S Fusion polypeptides with deamidase inhibitor and deamidase domains
WO2023194388A1 (en) 2022-04-07 2023-10-12 Novozymes A/S Fusion proteins and their use against eimeria
CN118765328A (zh) 2022-04-29 2024-10-11 诺维信公司 脂肪酸烷基酯的产生
WO2023250301A1 (en) 2022-06-21 2023-12-28 Danisco Us Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
WO2023247664A2 (en) 2022-06-24 2023-12-28 Novozymes A/S Lipase variants and compositions comprising such lipase variants
WO2024003143A1 (en) 2022-06-30 2024-01-04 Novozymes A/S Mutanases and oral care compositions comprising same
WO2024012912A1 (en) 2022-07-15 2024-01-18 Novozymes A/S Polypeptides having deamidase inhibitor activity
WO2024015974A1 (en) 2022-07-15 2024-01-18 Dupont Nutrition Biosciences Aps Improved enzymatic modification of phospholipids in food
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
WO2024050343A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Subtilisin variants and methods related thereto
WO2024050346A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Detergent compositions and methods related thereto
WO2024056643A1 (en) 2022-09-15 2024-03-21 Novozymes A/S Fungal signal peptides
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use
WO2024118901A2 (en) 2022-11-30 2024-06-06 Novozymes A/S Carbonic anhydrase variants and polynucleotides encoding same
WO2024120767A1 (en) 2022-12-05 2024-06-13 Novozymes A/S Modified rna polymerase activities
WO2024121070A1 (en) 2022-12-05 2024-06-13 Novozymes A/S Protease variants and polynucleotides encoding same
WO2024124013A1 (en) 2022-12-09 2024-06-13 International N&H Denmark Aps Feed formulations comprising a phytase for dairy ruminant animals
WO2024126483A1 (en) 2022-12-14 2024-06-20 Novozymes A/S Improved lipase (gcl1) variants
WO2024137246A1 (en) 2022-12-19 2024-06-27 Novozymes A/S Carbohydrate esterase family 1 (ce1) polypeptides having ferulic acid esterase and/or acetyl xylan esterase activity and polynucleotides encoding same
WO2024137250A1 (en) 2022-12-19 2024-06-27 Novozymes A/S Carbohydrate esterase family 3 (ce3) polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
WO2024133344A1 (en) 2022-12-20 2024-06-27 Novozymes A/S A method for providing a candidate biological sequence and related electronic device
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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607398B2 (en) * 1985-08-29 1991-03-07 Genencor Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
SK466390A3 (en) * 1989-09-27 2000-05-16 Gist Brocades Nv Purified and isolated dna sequence, construct, vector, transformed cell, peptide or protein having phytase activity, process for its preparation, and its use

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EP0489718B1 (en) 2004-11-10
FI871144A (fi) 1987-09-18
EP0238023A3 (en) 1989-02-22
EP1502952A2 (en) 2005-02-02
JPS62272988A (ja) 1987-11-27
EP0489718A1 (en) 1992-06-10
DE3788524T3 (de) 2003-04-24
DE3788524D1 (de) 1994-02-03
IE870682L (en) 1987-09-17
JPH0665316B2 (ja) 1994-08-24
ATE98993T1 (de) 1994-01-15
ES2061446T3 (es) 1994-12-16
EP0238023B2 (en) 2002-10-02
JP3903165B2 (ja) 2007-04-11
FI20011797A (fi) 2001-09-12
JPH0751067A (ja) 1995-02-28
FI871144A0 (fi) 1987-03-16
FI112376B (fi) 2003-11-28
JP3005618B2 (ja) 2000-01-31
ES2061446T5 (es) 2003-04-01
JPH10276787A (ja) 1998-10-20
CA1341593C (en) 2009-04-21
ATE282093T1 (de) 2004-11-15
DE3788524T2 (de) 1994-05-11
IE63169B1 (en) 1995-03-22
DE3752379D1 (de) 2004-12-16
DK122686D0 (da) 1986-03-17
EP1502952A3 (en) 2005-05-11
IE940343L (en) 1987-09-17
EP0238023B1 (en) 1993-12-22
DE3752379T2 (de) 2005-10-20
EP0238023A2 (en) 1987-09-23
JP2003153696A (ja) 2003-05-27

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