ATE123524T1 - Herstellungsverfahren für chymosin. - Google Patents

Herstellungsverfahren für chymosin.

Info

Publication number
ATE123524T1
ATE123524T1 AT92907324T AT92907324T ATE123524T1 AT E123524 T1 ATE123524 T1 AT E123524T1 AT 92907324 T AT92907324 T AT 92907324T AT 92907324 T AT92907324 T AT 92907324T AT E123524 T1 ATE123524 T1 AT E123524T1
Authority
AT
Austria
Prior art keywords
chymosin
prochymosin
filamentous fungus
derivative
sequence encoding
Prior art date
Application number
AT92907324T
Other languages
English (en)
Inventor
Tove Christensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE123524T1 publication Critical patent/ATE123524T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92907324T 1991-03-22 1992-03-20 Herstellungsverfahren für chymosin. ATE123524T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91610020 1991-03-22

Publications (1)

Publication Number Publication Date
ATE123524T1 true ATE123524T1 (de) 1995-06-15

Family

ID=8208768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92907324T ATE123524T1 (de) 1991-03-22 1992-03-20 Herstellungsverfahren für chymosin.

Country Status (7)

Country Link
EP (1) EP0575462B1 (de)
JP (1) JPH06505873A (de)
AT (1) ATE123524T1 (de)
AU (1) AU1430992A (de)
DE (1) DE69202858T2 (de)
DK (1) DK0575462T3 (de)
WO (1) WO1992016633A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480801A (en) * 1993-09-17 1996-01-02 Novo Nordisk A/S Purified PH neutral Rhizoctonia laccases and nucleic acids encoding same
US7390936B1 (en) 1999-08-23 2008-06-24 Sembiosys Genetics Inc. Commercial production of chymosin in plants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0625577A1 (de) * 1985-08-29 1994-11-23 Genencor International, Inc. Expression von heterologer Polypeptiden in filamentlözen Pilzen, Verfahren zu deren Herstellung und Vektoren zu deren Herstellung
DK122686D0 (da) * 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
GB8610600D0 (en) * 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma

Also Published As

Publication number Publication date
AU1430992A (en) 1992-10-21
DK0575462T3 (da) 1995-11-06
EP0575462B1 (de) 1995-06-07
DE69202858T2 (de) 1996-02-22
EP0575462A1 (de) 1993-12-29
WO1992016633A1 (en) 1992-10-01
DE69202858D1 (de) 1995-07-13
JPH06505873A (ja) 1994-07-07

Similar Documents

Publication Publication Date Title
DE69332981D1 (de) Methoden zur herstellung löslicher, oligomerer proteine
DE69532968D1 (de) Verfahren zur sekretion thrombopoitin polypeptide
CY1110494T1 (el) Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες
MX9703012A (es) Proceso para la produccion bacteriana de polipeptidos heterologos con enlaces disulfuro.
ATE86663T1 (de) Glucoamylasegen.
DE69227116T2 (de) Hochstabile rekombinante hefen für die herstellung von rekombinanten proteinen
IE883612L (en) Vectors and compounds for direct expression of activated human protein c
DE69231137D1 (de) Verfahren zur Herstellung von Peroxidasen in einem Aspergillusstamm
FI19991781A (fi) Parannettu biotekninen tuotantomenetelmä
NO885391D0 (no) Nye proteolytiske enzymer.
MXPA02001424A (es) Produccion de proteinas.
ATE123524T1 (de) Herstellungsverfahren für chymosin.
ES2075068T3 (es) Procedimiento de preparacion de una proteina mediante levaduras que utiliza un sistema inducible, vectores y cepas transformadas correspondientes.
MX9306021A (es) Nueva dipeptidil amino peptidasa aislada del moho del limo celular dictyostelium discoideum y metodopara su aislamiento.
ES2080759T3 (es) Produccion de proteinas o polipeptidos fusionados.
DE69434135D1 (de) Rekombinante dnase b aus streptococcus pyogenes
DE69834738D1 (de) Expressionssystem
WO1994011518A3 (en) Methods for converting a, ab, and b blood types to o blood type
ATE115626T1 (de) Verfahren zur herstellung von fremdprotein in escherichia coli.
DK0592574T3 (da) Fremgangsmåde til fremstilling af rekombinante proteiner og værtsceller anvendt derved
JO2429B1 (en) Ways to produce recombinant peptides of antigen - merger
ATE178655T1 (de) Herstellungsprozess von fremdprotein

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties