DK0877801T3 - Morfologiske mutanter af trådsvampe - Google Patents
Morfologiske mutanter af trådsvampeInfo
- Publication number
- DK0877801T3 DK0877801T3 DK97904806T DK97904806T DK0877801T3 DK 0877801 T3 DK0877801 T3 DK 0877801T3 DK 97904806 T DK97904806 T DK 97904806T DK 97904806 T DK97904806 T DK 97904806T DK 0877801 T3 DK0877801 T3 DK 0877801T3
- Authority
- DK
- Denmark
- Prior art keywords
- cell
- mutant
- parent
- filamentous fungi
- identifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/66—Aspergillus
- C12R2001/69—Aspergillus oryzae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/77—Fusarium
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1023896P | 1996-01-19 | 1996-01-19 | |
US72611496A | 1996-10-04 | 1996-10-04 | |
PCT/US1997/000829 WO1997026330A2 (en) | 1996-01-19 | 1997-01-17 | Morphological mutants of filamentous fungi |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0877801T3 true DK0877801T3 (da) | 2005-08-29 |
Family
ID=26680948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97904806T DK0877801T3 (da) | 1996-01-19 | 1997-01-17 | Morfologiske mutanter af trådsvampe |
Country Status (9)
Country | Link |
---|---|
US (5) | US6066493A (da) |
EP (3) | EP0877801B1 (da) |
JP (1) | JP3792725B2 (da) |
CN (1) | CN1231588C (da) |
AT (1) | ATE294233T1 (da) |
AU (1) | AU1750697A (da) |
DE (1) | DE69733121T2 (da) |
DK (1) | DK0877801T3 (da) |
WO (1) | WO1997026330A2 (da) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0877801B1 (en) * | 1996-01-19 | 2005-04-27 | Novozymes Biotech, Inc. | Morphological mutants of filamentous fungi |
US5811381A (en) * | 1996-10-10 | 1998-09-22 | Mark A. Emalfarb | Cellulase compositions and methods of use |
US7883872B2 (en) | 1996-10-10 | 2011-02-08 | Dyadic International (Usa), Inc. | Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose |
EP1525798B1 (en) | 1997-12-22 | 2011-11-23 | Novozymes A/S | Carbohydrate oxidase and use thereof in baking |
DE69922978T2 (de) * | 1998-10-06 | 2005-12-08 | Emalfarb, Mark Aaron, Jupiter | Transformationsystem in filamentösen fungiziden chrysosporium-wirtszellen |
US6361973B1 (en) | 1999-03-22 | 2002-03-26 | Novozymes Biotech, Inc. | Promoters for expressing genes in a fungal cell |
DK2278016T3 (da) | 1999-03-22 | 2012-11-26 | Novozymes Inc | Promotorsekvenser fra Fusarium Venenatum og anvendelse deraf |
US7189538B2 (en) * | 1999-03-24 | 2007-03-13 | Genencor International, Inc. | Hyphal growth in fungi |
US6995239B1 (en) * | 1999-03-24 | 2006-02-07 | Genencor International, Inc. | Hyphal growth in fungi |
US7122330B2 (en) | 2000-04-13 | 2006-10-17 | Mark Aaron Emalfarb | High-throughput screening of expressed DNA libraries in filamentous fungi |
WO2001079558A1 (en) * | 2000-04-13 | 2001-10-25 | Mark Aaron Emalfarb | High-throughput screening of expressed dna libraries in filamentous fungi |
US6558715B1 (en) * | 2000-10-31 | 2003-05-06 | Novozymes Biotech, Inc. | Methods for using lipases in baking |
EP2287296A1 (en) | 2000-06-26 | 2011-02-23 | Novozymes A/S | Lipolytic enzyme |
US6824798B2 (en) * | 2001-09-27 | 2004-11-30 | J. Gregory Koenig | Method of preventing veisalgia |
AU2003222664A1 (en) * | 2002-04-18 | 2003-11-03 | Genencor International, Inc. | Production of functional antibodies in filamentous fungi |
AU2003231028A1 (en) | 2002-04-22 | 2003-11-03 | Novozymes Biotech, Inc. | Methods for increasing homologous recombination of a nucleic acid sequence |
ATE460488T1 (de) | 2002-04-22 | 2010-03-15 | Novozymes Inc | Verfahren zur herstellung von varianten einer dna-sequenz in filamentösen pilzen |
ATE439432T1 (de) | 2002-08-30 | 2009-08-15 | Novozymes Inc | Verfahren zur herstellung von säugetier-trypsinen |
ATE542913T1 (de) | 2002-11-18 | 2012-02-15 | Novozymes Inc | Promotorvarianten zur expression von genen in einer pilzzelle |
EP1584675B1 (en) * | 2002-12-24 | 2010-02-24 | Ikeda Food Research Co. Ltd. | Coenzyme-binding glucose dehydrogenase |
ATE471370T1 (de) | 2003-05-02 | 2010-07-15 | Novozymes Inc | Varianten von beta-glukosidasen |
EP2617825B1 (en) | 2003-08-25 | 2015-04-01 | Novozymes, Inc. | Variants of glycoside hydrolases |
WO2005121333A1 (en) | 2004-06-14 | 2005-12-22 | Novozymes A/S | Signal peptide for producing a polypeptide |
US20060080393A1 (en) * | 2004-10-12 | 2006-04-13 | Cardone Richard J | Method for using e-mail documents to create and update address lists |
CN101287839B (zh) * | 2005-03-24 | 2015-04-08 | 帝斯曼知识产权资产管理有限公司 | 对有价值化合物进行微生物生产的方法 |
EP2368987A1 (en) | 2005-03-25 | 2011-09-28 | Ikeda Food Research Co. Ltd. | Coenzyme-linked glucose dehydrogenase and polynucleotide encoding the same |
US9862956B2 (en) | 2006-12-10 | 2018-01-09 | Danisco Us Inc. | Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi |
WO2008073914A2 (en) | 2006-12-10 | 2008-06-19 | Dyadic International Inc. | Expression and high-throughput screening of complex expressed dna libraries in filamentous fungi |
EP2121916A1 (en) * | 2006-12-20 | 2009-11-25 | Danisco US, INC., Genencor Division | Assays for improved fungal strains |
ATE517188T1 (de) | 2007-05-09 | 2011-08-15 | Novozymes As | Expressions-cloning-verfahren zur auswahl von bibliotheksklonen zur herstellung eines polypeptids von interesse |
CA2736661A1 (en) | 2007-09-07 | 2009-03-12 | Dyadic International, Inc. | Novel fungal enzymes |
BR122018077148B1 (pt) | 2009-12-18 | 2020-11-03 | Novozymes, Inc | mutante de uma cepa de trichoderma reesei parental isolada, e, métodos para produzir um polipeptídeo de inetresse e para obter um mutante de uma cepa de trichoderma reesei parental |
CN103003439A (zh) * | 2010-06-22 | 2013-03-27 | 中化帝斯曼制药有限公司荷兰公司 | 气泡发酵工艺 |
DK2748314T3 (da) | 2011-08-24 | 2017-03-20 | Novozymes Inc | Cellulolytiske enzymsammensætninger fra aspergillus fumigatus og anvendelser deraf |
AU2012298799B2 (en) | 2011-08-24 | 2018-02-01 | Novozymes, Inc. | Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell |
US9404101B2 (en) | 2011-08-24 | 2016-08-02 | Novozymes, Inc. | Methods for obtaining positive transformants of a filamentous fungal host cell |
BR112014004186B1 (pt) | 2011-08-24 | 2020-12-15 | Novozymes, Inc. | Composição enzimática, célula hospedeira de fungo filamentoso recombinante, método para produzir uma composição enzimática, processos para degradar um material celulósico, para sintetizar um produto de fermentação, e, para fermentar um material celulósico |
BR112014016587A2 (pt) | 2012-01-05 | 2020-10-27 | Novartis Ag | células fúngicas filamentosas deficientes de protease e métodos de uso das mesmas |
WO2013174927A1 (en) | 2012-05-23 | 2013-11-28 | Novartis International Pharmaceutical Limited | Production of fucosylated glycoproteins |
EP2885409A1 (en) | 2012-08-17 | 2015-06-24 | Novozymes A/S | Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof |
US10023872B2 (en) | 2012-12-21 | 2018-07-17 | Novozymes, Inc. | Methods for producing heterologous polypeptides in mutants of trichoderma |
WO2015004241A2 (en) | 2013-07-10 | 2015-01-15 | Novartis Ag | Multiple proteases deficient filamentous fungal cells and methods of use thereof |
EP3074513A1 (en) | 2013-11-26 | 2016-10-05 | Novozymes A/S | Enzyme compositions and uses thereof |
CN106488982A (zh) | 2014-06-06 | 2017-03-08 | 诺维信公司 | 酶组合物及其用途 |
EP3172333B1 (en) | 2014-07-21 | 2020-05-13 | Glykos Finland Oy | Production of glycoproteins with mammalian-like n-glycans in filamentous fungi |
WO2020123845A1 (en) | 2018-12-12 | 2020-06-18 | Novozymes A/S | Methods for increasing the productivity of a filamentous fungal cell in the production of a polypeptide |
EP4093188A1 (en) | 2020-01-24 | 2022-11-30 | Novozymes A/S | Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53118588A (en) * | 1977-03-28 | 1978-10-17 | Ajinomoto Co Inc | Preparation of peptidase |
US4288627A (en) | 1980-02-12 | 1981-09-08 | Phillips Petroleum Company | Oxidation of thiols employing cobalt molybdate/triethylamine catalyst |
US4816405A (en) * | 1984-10-24 | 1989-03-28 | The Regents Of The University Of California | Vectors for transformation by ascomycetes |
US5198345A (en) * | 1985-04-15 | 1993-03-30 | Gist-Brocades N.V. | Vectors in use in filamentous fungi |
US5364770A (en) * | 1985-08-29 | 1994-11-15 | Genencor International Inc. | Heterologous polypeptides expressed in aspergillus |
DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
US5536661A (en) * | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
DE3854249T2 (de) * | 1987-08-28 | 1996-02-29 | Novo Nordisk As | Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen. |
KR100237148B1 (ko) | 1990-05-09 | 2000-01-15 | 한센 핀 베네드 | 엔도글루칸아제 효소를 함유하는 셀룰라제 제조물 |
US5665585A (en) * | 1992-09-03 | 1997-09-09 | Alko-Yhiot Oy | Recombinant production of glucoamylase P in trichoderma |
GB9402604D0 (en) * | 1994-02-10 | 1994-04-06 | Zeneca Ltd | Microbiologial process |
CA2191718A1 (en) | 1994-06-03 | 1995-12-14 | Randy M. Berka | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
US5602004A (en) * | 1994-07-20 | 1997-02-11 | Novo Nordisk Biotech, Inc. | Thermophilic fungal expression system |
EP0877801B1 (en) * | 1996-01-19 | 2005-04-27 | Novozymes Biotech, Inc. | Morphological mutants of filamentous fungi |
JP4436934B2 (ja) * | 1996-09-13 | 2010-03-24 | ノボザイムス,インコーポレイティド | 変更された量のポリペプチドを生成するdna挿入突然変異を有する細胞 |
-
1997
- 1997-01-17 EP EP97904806A patent/EP0877801B1/en not_active Expired - Lifetime
- 1997-01-17 AT AT97904806T patent/ATE294233T1/de not_active IP Right Cessation
- 1997-01-17 EP EP10180181A patent/EP2295581A3/en not_active Withdrawn
- 1997-01-17 AU AU17506/97A patent/AU1750697A/en not_active Abandoned
- 1997-01-17 WO PCT/US1997/000829 patent/WO1997026330A2/en active IP Right Grant
- 1997-01-17 DK DK97904806T patent/DK0877801T3/da active
- 1997-01-17 JP JP52624197A patent/JP3792725B2/ja not_active Expired - Lifetime
- 1997-01-17 CN CNB971923663A patent/CN1231588C/zh not_active Expired - Lifetime
- 1997-01-17 DE DE69733121T patent/DE69733121T2/de not_active Expired - Lifetime
- 1997-01-17 EP EP05009106A patent/EP1605050A3/en not_active Ceased
- 1997-03-13 US US08/816,239 patent/US6066493A/en not_active Expired - Lifetime
-
1999
- 1999-09-24 US US09/405,564 patent/US6184026B1/en not_active Expired - Lifetime
-
2000
- 2000-11-02 US US09/705,390 patent/US6544774B1/en not_active Expired - Lifetime
-
2003
- 2003-02-25 US US10/374,247 patent/US6794180B2/en not_active Expired - Fee Related
-
2004
- 2004-06-30 US US10/883,346 patent/US7198938B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1997026330A2 (en) | 1997-07-24 |
US7198938B2 (en) | 2007-04-03 |
CN1219971A (zh) | 1999-06-16 |
EP1605050A3 (en) | 2006-03-22 |
DE69733121D1 (de) | 2005-06-02 |
EP1605050A2 (en) | 2005-12-14 |
US20040009579A1 (en) | 2004-01-15 |
US6184026B1 (en) | 2001-02-06 |
US6544774B1 (en) | 2003-04-08 |
ATE294233T1 (de) | 2005-05-15 |
US6794180B2 (en) | 2004-09-21 |
EP2295581A2 (en) | 2011-03-16 |
EP0877801B1 (en) | 2005-04-27 |
AU1750697A (en) | 1997-08-11 |
JP3792725B2 (ja) | 2006-07-05 |
CN1231588C (zh) | 2005-12-14 |
US6066493A (en) | 2000-05-23 |
DE69733121T2 (de) | 2006-03-02 |
WO1997026330A3 (en) | 1997-10-09 |
EP0877801A2 (en) | 1998-11-18 |
EP2295581A3 (en) | 2011-05-04 |
JP2000503537A (ja) | 2000-03-28 |
US20040266009A1 (en) | 2004-12-30 |
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