ATE471370T1 - Varianten von beta-glukosidasen - Google Patents

Varianten von beta-glukosidasen

Info

Publication number
ATE471370T1
ATE471370T1 AT04751000T AT04751000T ATE471370T1 AT E471370 T1 ATE471370 T1 AT E471370T1 AT 04751000 T AT04751000 T AT 04751000T AT 04751000 T AT04751000 T AT 04751000T AT E471370 T1 ATE471370 T1 AT E471370T1
Authority
AT
Austria
Prior art keywords
beta
glucosidases
variants
positions
seq
Prior art date
Application number
AT04751000T
Other languages
English (en)
Inventor
Michael Lamsa
Ana Fidantsef
Brian Gorre-Clancy
Original Assignee
Novozymes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Inc filed Critical Novozymes Inc
Application granted granted Critical
Publication of ATE471370T1 publication Critical patent/ATE471370T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445Beta-glucosidase (3.2.1.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021Beta-glucosidase (3.2.1.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04751000T 2003-05-02 2004-04-30 Varianten von beta-glukosidasen ATE471370T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46776703P 2003-05-02 2003-05-02
US52834203P 2003-12-09 2003-12-09
PCT/US2004/013401 WO2004099228A2 (en) 2003-05-02 2004-04-30 Variants of beta-glucosidases

Publications (1)

Publication Number Publication Date
ATE471370T1 true ATE471370T1 (de) 2010-07-15

Family

ID=33436742

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04751000T ATE471370T1 (de) 2003-05-02 2004-04-30 Varianten von beta-glukosidasen

Country Status (7)

Country Link
US (4) US7413888B2 (de)
EP (2) EP2228440B1 (de)
AT (1) ATE471370T1 (de)
DE (1) DE602004027723D1 (de)
DK (2) DK1622921T3 (de)
ES (2) ES2347658T3 (de)
WO (1) WO2004099228A2 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1902310B (zh) 2003-10-28 2011-09-21 诺维信股份有限公司 具有β-葡糖苷酶活性的多肽和编码所述多肽的多核苷酸
US8546106B2 (en) 2006-07-21 2013-10-01 Novozymes, Inc. Methods of increasing secretion of polypeptides having biological activity
NZ581257A (en) * 2007-05-31 2012-03-30 Novozymes Inc Compositions for degrading cellulosic material
CN104726350A (zh) * 2007-06-08 2015-06-24 丹尼斯科美国公司 异源和同源纤维素酶表达体系
WO2009076655A2 (en) 2007-12-13 2009-06-18 University Of Washington Synthetic enzymes derived from computational design
NZ598403A (en) 2007-12-19 2012-07-27 Novozymes As Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
NZ587525A (en) * 2008-03-06 2012-02-24 Novozymes As Polypeptides having beta-glucosidase activity and polynucleotides encoding same
CA2722189A1 (en) * 2008-04-21 2009-10-29 Chromatin, Inc. Methods and materials for processing a feedstock
CN102482656A (zh) * 2008-08-29 2012-05-30 埃欧金能源公司 具有提高的稳定性的经修饰的β-糖苷酶
FR2935986B1 (fr) * 2008-09-12 2012-11-23 Inst Francais Du Petrole Variants de beta-glucosidase a activite amelioree et leurs utilisations.
CN102292444A (zh) 2008-11-20 2011-12-21 诺维信股份有限公司 具有淀粉分解增强活性的多肽和编码该多肽的多核苷酸
BRPI0923026A2 (pt) 2008-12-19 2017-03-28 Novozymes Inc métodos para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico.
WO2010080527A1 (en) 2008-12-19 2010-07-15 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
CA2752818A1 (en) 2009-02-26 2010-09-02 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides
US9012186B2 (en) 2009-04-27 2015-04-21 The Board Of Trustees Of The University Of Illinois Hemicellulose-degrading enzymes
KR101183114B1 (ko) 2009-05-08 2012-09-27 대한민국 백색부후균 유래 베타-글루코시다아제 유전자, 상기 유전자를 함유한 발현벡터, 상기 발현벡터로 형질전환된 형질전환체 및 상기 형질전환체의 제조방법
US8486683B2 (en) * 2009-05-29 2013-07-16 Iogen Energy Corporation Beta-glucosidase enzymes
EP2443235A4 (de) * 2009-06-16 2013-07-31 Codexis Inc ß-GLUCOSIDASE-VARIANTEN
US8569581B2 (en) 2009-09-17 2013-10-29 Novozymes, Inc Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
DK2496692T3 (en) 2009-11-06 2016-06-27 Novozymes Inc POLYPEPTIDES WITH xylanase AND POLYNUCLEOTIDES ENCODING THEM
CA2780179A1 (en) 2009-11-06 2011-05-12 Novozymes, Inc. Compositions for saccharification of cellulosic material
EP2599862B1 (de) * 2009-11-20 2017-08-02 Danisco US Inc. Beta-Glucosidase-Varianten mit verbesserten Eigenschaften
EP2706119B1 (de) * 2009-11-25 2015-08-12 Codexis, Inc. Rekombinante Beta-Glucosidase-Varianten zur Herstellung von löslichen Zuckern aus zellulosischer Biomasse
US8652813B2 (en) * 2009-11-25 2014-02-18 Codexis, Inc. Recombinant Thermoascus aurantiacus β-glucosidase variants
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
CN102918151B (zh) 2010-03-31 2015-09-09 诺维信股份有限公司 纤维二糖水解酶变体及编码其的多核苷酸
CN102296053B (zh) * 2010-06-25 2015-03-11 中国医学科学院药物研究所 一种7-木糖紫杉烷糖基水解酶、其基因的核苷酸序列及其应用
WO2012021400A1 (en) 2010-08-12 2012-02-16 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof
DK2622068T3 (en) 2010-09-30 2016-10-17 Novozymes Inc Variants of polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM
DK2622070T3 (en) 2010-09-30 2016-11-21 Novozymes Inc Variants of polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM
CN105886485B (zh) 2010-10-01 2019-09-24 诺维信股份有限公司 β-葡糖苷酶变体及其编码多核苷酸
US9676830B2 (en) 2010-11-18 2017-06-13 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8927235B2 (en) 2010-12-06 2015-01-06 Novozymes A/S Methods of hydrolyzing oligomers in hemicellulosic liquor
EP2703484A4 (de) * 2011-03-24 2014-12-31 Asahi Glass Co Ltd Transformant aus hefe der art schizosaccharomyces, herstellungsverfahren dafür, verfahren zur herstellung von beta-glucosidase und verfahren zur zersetzung von zellulose
US9926547B2 (en) 2011-04-28 2018-03-27 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US9624518B2 (en) 2011-04-29 2017-04-18 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
CN103917649A (zh) 2011-08-19 2014-07-09 诺维信股份有限公司 用于生产c4-二羧酸的重组微生物
AU2012298713B2 (en) 2011-08-24 2017-11-23 Novozymes, Inc. Methods for obtaining positive transformants of a filamentous fungal host cell
IN2014CN02136A (de) 2011-08-24 2015-05-29 Novozymes Inc
WO2013028927A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof
DK2760885T3 (en) 2011-09-30 2017-10-30 Novozymes Inc CHEMICAL POLYPEPTIDES WITH BETA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
US10036050B2 (en) 2011-12-20 2018-07-31 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
EP2885409A1 (de) 2012-08-17 2015-06-24 Novozymes A/S Verfahren zur co-ausschaltung der expression von genen in fadenpilzstämmen und verwendungen davon
WO2014060380A1 (en) * 2012-10-16 2014-04-24 Dsm Ip Assets B.V. Cell wall deconstruction enzymes of thermoascus aurantiacus and uses thereof
KR101400010B1 (ko) 2012-12-26 2014-05-28 주식회사 코젠 베타글루칸 하이드롤레이즈 스크리닝 방법
JP6368968B2 (ja) * 2014-01-22 2018-08-08 本田技研工業株式会社 形質転換体の製造方法、糖化酵素の生産方法、及び草木類バイオマスの糖化処理方法
WO2015134729A1 (en) 2014-03-05 2015-09-11 Novozymes A/S Compositions and methods for improving properties of non-cellulosic textile materials with xyloglucan endotransglycosylase
CN106062271A (zh) 2014-03-05 2016-10-26 诺维信公司 用于改进具有木葡聚糖内糖基转移酶的纤维素纺织材料的性质的组合物和方法
WO2015134776A1 (en) 2014-03-05 2015-09-11 Novozymes A/S Compositions and methods for improving post-harvest properties of agricultural crops
AR099683A1 (es) 2014-03-05 2016-08-10 Novozymes Bioag As Composiciones que comprenden polímeros de xiloglucano como portador para agentes agrícolamente benéficos
CN106062276B (zh) 2014-03-05 2019-06-11 诺维信公司 用于将材料功能化并且进行连接的组合物和方法
US20170267980A1 (en) 2014-08-20 2017-09-21 Novozymes A/S Xyloglucan Endotransglycosylase variants and Polynucleotides Encoding Same
US10781428B2 (en) 2014-12-02 2020-09-22 Novozymes A/S Laccase variants and polynucleotides encoding same
CN104450651B (zh) * 2014-12-09 2017-08-15 青岛蔚蓝生物集团有限公司 一种β‑葡萄糖苷酶突变体及其应用
US10626430B2 (en) 2015-01-20 2020-04-21 Suntory Holdings Limited Method for preparing mogroside having no β-1,6-glucoside bond
EA036683B1 (ru) 2015-04-10 2020-12-08 Комет Биорефайнинг Инк. Способы и составы для обработки целлюлозной биомассы и продукты на ее основе
US20180171271A1 (en) * 2015-06-30 2018-06-21 Novozymes A/S Laundry detergent composition, method for washing and use of composition
DK3387139T3 (da) * 2015-12-10 2020-07-20 Dsm Ip Assets Bv Beta-glucosidase og anvendelser deraf
CN105567662B (zh) * 2016-01-28 2018-09-07 中国农业科学院饲料研究所 一种嗜热β-葡萄糖苷酶突变体-M36N及其编码基因和应用
CA3099535C (en) 2018-05-10 2024-01-16 Comet Biorefining Inc. Compositions comprising glucose and hemicellulose and their use

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (de) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ES2058119T3 (es) 1986-08-29 1994-11-01 Novo Nordisk As Aditivo detergente enzimatico.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
EP0305216B1 (de) 1987-08-28 1995-08-02 Novo Nordisk A/S Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen
JPH01144992A (ja) 1987-11-30 1989-06-07 Agency Of Ind Science & Technol 融合タンパク質の作成方法
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
EP0394352B1 (de) 1988-01-07 1992-03-11 Novo Nordisk A/S Enzymatisches waschmittel
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US5648263A (en) 1988-03-24 1997-07-15 Novo Nordisk A/S Methods for reducing the harshness of a cotton-containing fabric
EP0406314B1 (de) 1988-03-24 1993-12-01 Novo Nordisk A/S Cellulosezubereitung
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
NZ237549A (en) 1990-03-23 1993-06-25 Gist Brocades Nv Production of enhanced levels of enzymes in the seeds of transgenic plants and the use of these seeds
ES2055601T3 (es) 1990-04-14 1994-08-16 Kali Chemie Ag Lipasas alcalinas de bacillus, secuencias de adn que las codifican, asi como bacilli que producen estas lipasas.
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
WO1991017243A1 (en) 1990-05-09 1991-11-14 Novo Nordisk A/S A cellulase preparation comprising an endoglucanase enzyme
WO1992005249A1 (en) 1990-09-13 1992-04-02 Novo Nordisk A/S Lipase variants
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
SG52693A1 (en) 1991-01-16 1998-09-28 Procter & Gamble Detergent compositions with high activity cellulase and softening clays
HU213044B (en) 1991-04-30 1997-01-28 Procter & Gamble Built liquid detergents with boric-polyol complex to inhibit proteolytic enzyme with additives improving detergent effect
EP0511456A1 (de) 1991-04-30 1992-11-04 The Procter & Gamble Company Flüssiges Reinigungsmittel mit einem aromatischen Boratester zur Inhibierung des proteolytischen Enzyms
US5858757A (en) 1991-05-01 1999-01-12 Novo Nordisk A/S Stabilized enzymes and detergent compositions
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
JP3678309B2 (ja) 1992-07-23 2005-08-03 ノボザイムス アクティーゼルスカブ 突然変異α−アミラーゼ、洗剤、皿洗い剤及び液化剤
KR100303619B1 (ko) 1992-10-06 2001-11-22 피아 스타르 셀룰라제변이체
ATE175235T1 (de) 1993-02-11 1999-01-15 Genencor Int Oxidativ stabile alpha-amylase
PL306812A1 (en) 1993-04-27 1995-04-18 Gist Brocades Nv Novel lipase variants suitable for use in detergents
DK52393D0 (de) 1993-05-05 1993-05-05 Novo Nordisk As
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
BR9407808A (pt) 1993-10-13 1997-05-06 Novo Nordisk As Variante de peroxidase com melhorada estabilidade para peróxido de hidrogenio em condições alcalinas composição de alvejamento e composição detergente
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
CA2183431A1 (en) 1994-02-22 1995-08-24 Allan Svendsen A method of preparing a variant of a lipolytic enzyme
DE69534513T2 (de) 1994-03-08 2006-07-27 Novozymes A/S Neuartige alkalische zellulasen
DE69528524T2 (de) 1994-05-04 2003-06-26 Genencor International, Inc. Lipasen mit verbesserten tensiostabilitaet
JP3649338B2 (ja) 1994-06-03 2005-05-18 ノボザイムス バイオテック,インコーポレイティド 精製されたマイセリオフトラ・ラッカーゼ及びそれをコードする核酸
WO1995035381A1 (en) 1994-06-20 1995-12-28 Unilever N.V. Modified pseudomonas lipases and their use
AU2884695A (en) 1994-06-23 1996-01-19 Unilever Plc Modified pseudomonas lipases and their use
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
US5919691A (en) 1994-10-06 1999-07-06 Novo Nordisk A/S Enzyme and enzyme preparation with endoglucanase activity
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
US5827719A (en) 1994-10-26 1998-10-27 Novo Nordisk A/S Enzyme with lipolytic activity
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
AU715423B2 (en) 1995-03-17 2000-02-03 Novozymes A/S Novel endoglucanases
WO1997004078A1 (en) 1995-07-14 1997-02-06 Novo Nordisk A/S A modified enzyme with lipolytic activity
ES2221934T3 (es) 1995-08-11 2005-01-16 Novozymes A/S Nuevas enzimas lipoliticas.
EP0843725B1 (de) 1995-08-11 2002-04-17 Novozymes A/S Verfahren zur herstellung von polypeptidabkömmlingen
EP0877801B1 (de) 1996-01-19 2005-04-27 Novozymes Biotech, Inc. Morphologische mutanten von filamentösen pilzen
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
CA2258292A1 (en) 1996-06-28 1998-01-08 Novo Nordisk A/S A recombinant enzyme with dextranase activitiy
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
ATE324437T1 (de) 1996-09-17 2006-05-15 Novozymes As Cellulasevarianten
EP0963192B1 (de) 1996-10-08 2003-01-08 Novozymes A/S Diaminobenzoesäure derivate als farbstoffvorläufer
ATE510910T1 (de) 1996-11-04 2011-06-15 Novozymes As Subtilase-varianten und verbindungen
CA2270180C (en) 1996-11-04 2011-01-11 Novo Nordisk A/S Subtilase variants and compositions
US6159731A (en) 1997-02-12 2000-12-12 Massachusetts Institute Of Technology Daxx, a Fas-binding protein that activates JNK and apoptosis
DK0996718T3 (da) 1997-03-18 2009-04-06 Novozymes As Fremgangsmåde til konstruktion af et bibliotek ved anvendelse af DNA-shuffling
CA2284097A1 (en) 1997-03-18 1998-09-24 Novo Nordisk A/S Shuffling of heterologous dna sequences
US6015703A (en) 1998-03-10 2000-01-18 Iogen Corporation Genetic constructs and genetically modified microbes for enhanced production of beta-glucosidase
EP1080210A2 (de) 1998-05-27 2001-03-07 Novo Nordisk Biotech, Inc. Methoden zur herstellung eines polypeptides durch modifizierung der kopiezahl des gens
WO2000024883A1 (en) 1998-10-26 2000-05-04 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
FR2799364B1 (fr) 1999-10-12 2001-11-23 Jacques Seguin Dispositif d'annuloplastie utilisable par voie mini-invasive
ES2272333T3 (es) * 1999-11-19 2007-05-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Procedimiento para aumentar el nivel de una sustancia de fermentacion.
JP4927281B2 (ja) 1999-11-30 2012-05-09 ノボザイムス,インコーポレイティド 共通翻訳開始配列を用いるポリペプチドの産生方法
EP1395653A2 (de) 2001-05-18 2004-03-10 Novozymes A/S Polypeptide mit cellobiaseaktivität und diese codierende polypeptide

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EP1622921B1 (de) 2010-06-16
ES2393058T3 (es) 2012-12-18
US20090053765A1 (en) 2009-02-26
US7638616B2 (en) 2009-12-29
WO2004099228A3 (en) 2005-12-29
US20040253702A1 (en) 2004-12-16
US20150099280A1 (en) 2015-04-09
EP1622921A2 (de) 2006-02-08
DK1622921T3 (da) 2010-09-13
ES2347658T3 (es) 2010-11-03
DE602004027723D1 (de) 2010-07-29
EP2228440A1 (de) 2010-09-15
DK2228440T3 (da) 2013-01-02
WO2004099228A2 (en) 2004-11-18
US20100099146A1 (en) 2010-04-22
US7413888B2 (en) 2008-08-19
US9080165B2 (en) 2015-07-14
EP2228440B1 (de) 2012-08-22
US8852913B2 (en) 2014-10-07
EP1622921A4 (de) 2006-12-27

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