ATE294871T1 - Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren - Google Patents

Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren

Info

Publication number
ATE294871T1
ATE294871T1 AT95922334T AT95922334T ATE294871T1 AT E294871 T1 ATE294871 T1 AT E294871T1 AT 95922334 T AT95922334 T AT 95922334T AT 95922334 T AT95922334 T AT 95922334T AT E294871 T1 ATE294871 T1 AT E294871T1
Authority
AT
Austria
Prior art keywords
toxic
toxigen
promotors
terminators
expression system
Prior art date
Application number
AT95922334T
Other languages
English (en)
Inventor
John C Royer
Donna L Moyer
Wendy Yoder
Jeffrey R Shuster
Original Assignee
Novozymes Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biotech Inc filed Critical Novozymes Biotech Inc
Application granted granted Critical
Publication of ATE294871T1 publication Critical patent/ATE294871T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/929—Fusarium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT95922334T 1994-06-30 1995-06-15 Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren ATE294871T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26944994A 1994-06-30 1994-06-30
US40467895A 1995-03-15 1995-03-15
PCT/US1995/007743 WO1996000787A1 (en) 1994-06-30 1995-06-15 Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein

Publications (1)

Publication Number Publication Date
ATE294871T1 true ATE294871T1 (de) 2005-05-15

Family

ID=26953701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95922334T ATE294871T1 (de) 1994-06-30 1995-06-15 Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren

Country Status (9)

Country Link
US (1) US5837847A (de)
EP (2) EP1559776A3 (de)
JP (2) JP3167729B2 (de)
CN (2) CN101659926A (de)
AT (1) ATE294871T1 (de)
AU (1) AU2705895A (de)
DE (1) DE69534185T2 (de)
FI (1) FI119437B (de)
WO (1) WO1996000787A1 (de)

Families Citing this family (714)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0959128B1 (de) * 1996-07-24 2006-08-30 Meiji Seika Kabushiki Kaisha Endoglucanase-enzym und cellulase-zusammensetzungen, die dieses enthalten
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
WO1998051803A1 (en) 1997-05-16 1998-11-19 Novo Nordisk Biotech, Inc. Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same
CN1231579C (zh) * 1998-05-20 2005-12-14 诺沃奇梅兹生物技术有限公司 trichodiene合成酶及其制备方法
ATE286136T1 (de) * 1998-10-06 2005-01-15 Mark Aaron Emalfarb Transformationsystem in filamentösen fungiziden chrysosporium-wirtszellen
JP5043254B2 (ja) 1998-10-26 2012-10-10 ノボザイムス アクティーゼルスカブ 糸状面細胞内の問題のdnaライブラリーの作製及びスクリーニング
ES2296606T3 (es) * 1999-01-13 2008-05-01 Novozymes, Inc. Metodos de produccion de polipeptidos en celulas deficientes en ciclohexadepsipeptido.
US6361973B1 (en) 1999-03-22 2002-03-26 Novozymes Biotech, Inc. Promoters for expressing genes in a fungal cell
EP1194572A2 (de) * 1999-03-22 2002-04-10 Novozymes Biotech, Inc. Promotorsequenzen von fusarium venenatum und deren verwendungen
EP2206786A1 (de) 1999-08-31 2010-07-14 Novozymes A/S Neue Proteasen und Varianten davon
HUP0203751A3 (en) 2000-01-10 2005-01-28 Maxygen Holdings Ltd Redwood C G-csf conjugates
WO2001058935A2 (en) 2000-02-11 2001-08-16 Maxygen Aps FACTOR VII OR VIIa-LIKE MOLECULES
CN102174535B (zh) 2000-03-14 2014-04-09 诺维信公司 在制备多肽的方法中有效的真菌转录激活因子
AU2001267333A1 (en) 2000-06-26 2002-01-08 Novozymes A/S Lipolytic enzyme
WO2002016547A2 (en) 2000-08-21 2002-02-28 Novozymes A/S Subtilase enzymes
CA2419577A1 (en) 2000-09-05 2002-03-14 Novozymes A/S Manganese lipoxygenase
EP1366075B1 (de) 2001-02-27 2009-05-27 Maxygen Aps Neue interferon-beta-ähnliche moleküle
ES2338767T3 (es) 2001-04-20 2010-05-12 Novozymes A/S Variantes de lipoxigenasa y su uso.
DK2295544T3 (en) 2001-06-26 2016-09-26 Novozymes As Polypeptides with cellobiohydrolase I activity and the same coding polynucleotides
DE10207702C1 (de) * 2002-02-22 2003-08-28 Albrecht Gmbh Einstellbare Gelenkorthese
EP1499739B1 (de) 2002-04-22 2016-03-30 Novozymes, Inc. Verfahren zur erhöhung der homologen rekombination einer nukleinsäuresequenz
AU2003231228A1 (en) 2002-04-22 2003-11-03 Novozymes Biotech, Inc. Methods for preparing variants of a dna sequence in filamentous fungi
CN1694953B (zh) * 2002-08-30 2010-05-12 诺维信股份有限公司 制备哺乳动物胰蛋白酶的方法
US7364892B2 (en) * 2002-09-24 2008-04-29 Novozymes, Inc. Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
ATE540108T1 (de) 2002-10-01 2012-01-15 Novozymes As Familie gh 61 polypeptiden
ATE542913T1 (de) 2002-11-18 2012-02-15 Novozymes Inc Promotorvarianten zur expression von genen in einer pilzzelle
WO2004056981A2 (en) 2002-12-20 2004-07-08 Novozymes A/S Polypeptides having cellobiohydrolase ii activity and polynucleotides encoding same
DK1613761T3 (da) 2003-03-31 2009-12-14 Novozymes Inc Fremgangsmåder til fremstilling af biologiske stoffer i enzymdefekte mutanter af Aspergillus niger
DK1620551T3 (da) 2003-04-28 2014-01-13 Chr Hansen As Phospholipase og fremgangsmåde til fremstilling deraf
ATE471370T1 (de) 2003-05-02 2010-07-15 Novozymes Inc Varianten von beta-glukosidasen
EP1639106B1 (de) 2003-06-19 2010-05-26 Novozymes A/S Proteasen
EP1639107B1 (de) 2003-06-19 2013-08-14 Novozymes A/S Verbesserte proteasen und methoden zu deren herstellung
AU2004252572B2 (en) 2003-06-25 2011-09-08 Novozymes A/S Polypeptides having alpha-amylase activity and polypeptides encoding same
ES2538824T3 (es) 2003-08-25 2015-06-24 Novozymes, Inc. Variantes de glucósido hidrolasas
WO2005040372A1 (en) 2003-10-23 2005-05-06 Novozymes A/S Protease with improved stability in detergents
MXPA06004463A (es) 2003-10-28 2006-06-27 Novozymes North America Inc Enzimas hibridas.
DK1682656T3 (da) 2003-10-28 2013-11-18 Novozymes Inc Polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem
WO2005066339A2 (en) 2004-01-06 2005-07-21 Novozymes A/S Polypeptides of alicyclobacillus sp.
DK1713825T3 (da) 2004-01-30 2012-11-05 Novozymes Inc Polypeptider med cellulolytisk forøgende aktivitet og polynukleotider der koder for samme
WO2006078256A2 (en) 2004-02-12 2006-07-27 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
JP4891220B2 (ja) 2004-02-25 2012-03-07 ノボザイムス アクティーゼルスカブ 菌類細胞壁分解酵素
PT3219806T (pt) 2004-03-25 2020-06-30 Novozymes Inc Métodos para degradar ou converter polissacarídeos da parede celular de plantas
CA2560205A1 (en) 2004-04-16 2005-10-27 Dsm Ip Assets B.V. Fungal promoters for expressing a gene in a fungal cell
US7148404B2 (en) 2004-05-04 2006-12-12 Novozymes A/S Antimicrobial polypeptides
WO2005121351A2 (en) 2004-05-27 2005-12-22 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a dna library
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
EP1751281A2 (de) 2004-05-27 2007-02-14 Genencor International, Inc. Säurestabile alpha-amylase aus aspergillus kawachi und anwendungen bei der stärkegranulathydrolyse
DK1756273T3 (da) 2004-06-14 2010-02-01 Novozymes As Signalpeptid til frembringelse af et polypeptid
WO2005123915A1 (en) 2004-06-21 2005-12-29 Novozymes A/S Stably maintained multiple copies of at least two orf in the same orientation
CN101014704A (zh) 2004-06-21 2007-08-08 诺维信公司 蛋白酶
WO2006005032A2 (en) 2004-06-29 2006-01-12 Novozymes, Inc. Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
US7666630B2 (en) 2004-09-30 2010-02-23 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encoding same
EP1809747B1 (de) 2004-10-04 2016-12-14 Novozymes A/S Polypeptide mit phytaseaktivität und dafür codierende polynukleotide
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
EP1814996A2 (de) 2004-11-19 2007-08-08 Novozymes A/S Polypeptide mit antimikrobieller aktivität und diese codierende polynukleotide
MX2007007107A (es) 2004-12-22 2007-08-08 Novozymes North America Inc Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que los codifican.
DK2410048T3 (en) 2005-01-24 2016-11-28 Dsm Ip Assets Bv A process for the preparation of a compound of interest in a filamentous fungal cell
EP1861421B1 (de) 2005-03-16 2011-10-19 Novozymes Adenium Biotech A/S Rekombinante expression von insekten defensinen in aspergillus
AU2006226729B2 (en) 2005-03-22 2012-02-16 Novozymes A/S Polypeptides and nucleic acids encoding same
AR053066A1 (es) 2005-04-26 2007-04-18 Novozymes As Arabinofuranosidasas
CA2606475C (en) 2005-04-27 2015-06-16 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US8119387B2 (en) 2005-08-16 2012-02-21 Novozymes A/S Polypeptides of strain Bacillus sp. P203
AU2006283904B2 (en) 2005-08-26 2012-07-12 Novozymes Adenium Biotech A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP1941023B1 (de) 2005-09-30 2017-04-05 Novozymes Inc. Verfahren zur verstärkung des verfalls oder der umwandlung von cellulose-material
DK1941025T3 (da) 2005-10-17 2011-09-26 Novozymes As Brug af svampemutanter til ekspression af antistoffer
EA014783B1 (ru) 2005-11-29 2011-02-28 ДСМ АйПи АССЕТС Б.В. Связывающий днк-сайт активатора транскрипции, пригодный для экспрессии генов
EP1999257B1 (de) 2006-03-20 2011-06-22 Novozymes, Inc. Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
EP2004817A2 (de) 2006-03-30 2008-12-24 Novozymes, Inc. Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
DK2365064T3 (en) 2006-04-04 2015-03-30 Novozymes As Phytasevarianter
US20080026376A1 (en) 2006-07-11 2008-01-31 Huaming Wang KEX2 cleavage regions of recombinant fusion proteins
US8198046B2 (en) 2006-07-11 2012-06-12 Danisco Us Inc. KEX2 cleavage regions of recombinant fusion proteins
WO2008008950A2 (en) 2006-07-14 2008-01-17 Novozymes, Inc. Methods for producing secreted polypeptides having biological activity
CN101512001A (zh) 2006-07-14 2009-08-19 诺维信股份有限公司 提高真菌细胞中基因表达的方法
WO2008057637A2 (en) 2006-07-21 2008-05-15 Novozymes, Inc. Methods of increasing secretion of polypeptides having biological activity
CN101517084B (zh) 2006-09-22 2014-12-10 丹尼斯科美国公司 来自里氏木霉的乙酰乳酸合酶(als)选择性标记
EP2061882A2 (de) 2006-10-10 2009-05-27 Danisco US, INC., Genencor Division Glucoamylasevarianten mit veränderten eigenschaften
EP2431470B1 (de) 2006-11-30 2017-11-29 Novozymes A/S Rekombinante wirtszellen der dnase-expression
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
EP2505651A3 (de) 2006-12-10 2013-01-09 Dyadic International, Inc. Pilzisolate mit reduzierter Proteaseaktivität
WO2008076323A2 (en) 2006-12-18 2008-06-26 Danisco Us, Inc., Genencor Division Laccase mediators and methods of use
US20080220498A1 (en) 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
EP2631295A3 (de) 2007-02-15 2014-01-01 DSM IP Assets B.V. Rekombinante Hostzelle zur Herstellung einer Verbindung von Interesse
DK2129781T3 (da) 2007-03-26 2014-03-31 Novozymes As Hafnia-phytase
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
CN101679993A (zh) 2007-05-09 2010-03-24 诺维信公司 适于选择产生目标多肽的文库克隆的表达克隆方法
DK2147104T3 (en) 2007-05-21 2015-12-14 Danisco Us Inc USING A ASPARAGINPROTEASE- (NSP24) SIGNAL SEQUENCE FOR heterologous protein EXPRESSION
JP2010536385A (ja) 2007-08-24 2010-12-02 コデクシス, インコーポレイテッド (r)−3−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド
WO2009033071A2 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
WO2009035500A1 (en) 2007-09-12 2009-03-19 Danisco Us Inc., Genencor Division Trichoderma promoter
EP2193195B1 (de) 2007-09-18 2014-12-17 Novozymes A/S Polypeptide mit tyrosinaseaktivität und für diese kodierende polynukleotide
PL2481796T3 (pl) 2007-10-09 2014-11-28 Danisco Us Inc Odmiany glukoamylazy
US8592194B2 (en) 2007-10-09 2013-11-26 Danisco Us Inc. Glucoamylase variants with altered properties
BRPI0820483B1 (pt) 2007-11-20 2022-04-12 Danisco Us Inc Variantes de glicoamilase com propriedades alteradas e composição compreendendo as mesmas
US7867745B2 (en) 2007-11-27 2011-01-11 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
ES2490608T3 (es) 2007-12-06 2014-09-04 Novozymes A/S Polipéptidos con actividad de esterasa de acetilxilano y polinucleótidos que codifican los mismos
EP2235173A2 (de) 2007-12-19 2010-10-06 Novozymes A/S Polypeptide mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
US8673609B2 (en) 2008-04-18 2014-03-18 Danisco Us Inc. Buttiauxella sp. phytase variants
AU2009254546B2 (en) 2008-06-06 2014-09-25 Novozymes A/S Variants of a family 44 xyloglucanase
EP2481737A1 (de) 2008-06-24 2012-08-01 Merck Sharp & Dohme Corp. Biokatalytische Verfahren zur Herstellung substantiell stereomer reinkondensierter, bicyclischer Prolinverbindungen
WO2010025238A2 (en) 2008-08-27 2010-03-04 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
MX2011003132A (es) 2008-09-26 2011-04-21 Novozymes As Variantes de fitasa de hafnia.
WO2010059413A2 (en) 2008-11-20 2010-05-27 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US7771983B2 (en) 2008-12-04 2010-08-10 Novozymos, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
WO2010068800A1 (en) 2008-12-12 2010-06-17 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
WO2010074972A1 (en) 2008-12-15 2010-07-01 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
US20110271407A1 (en) 2008-12-16 2011-11-03 Novozymes, Inc. Polypeptides Having Alpha-Mannosidase Activity And Polynucleotides Encoding Same
WO2010074955A1 (en) 2008-12-16 2010-07-01 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
CN107190030A (zh) 2008-12-19 2017-09-22 诺维信股份有限公司 在纤维二糖脱氢酶存在下增加纤维素材料水解的方法
US8338121B2 (en) 2008-12-19 2012-12-25 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
EP2379733A2 (de) 2008-12-19 2011-10-26 Novozymes Inc. Verfahren zur steigerung der hydrolyse von cellulosehaltigem material
CA2747056A1 (en) 2008-12-19 2010-07-15 Novozymes, Inc. Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
EP3444343B1 (de) 2008-12-23 2020-10-28 DuPont Nutrition Biosciences ApS Polypeptide
HUE036104T2 (hu) 2009-01-08 2018-06-28 Codexis Inc Transzamináz polipeptidek
CN102361973B (zh) 2009-01-21 2015-09-02 诺维信公司 具有酯酶活性的多肽和编码该多肽的核酸
WO2010088387A1 (en) 2009-01-28 2010-08-05 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010088463A2 (en) 2009-01-30 2010-08-05 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2408314A1 (de) 2009-03-17 2012-01-25 Novozymes A/S Polypeptide mit tyrosinaseaktivität und für diese codierende polynukleotide
CN102365360A (zh) 2009-03-24 2012-02-29 诺维信公司 具有乙酰木聚糖酯酶活性的多肽和编码该多肽的多核苷酸
CN102428170B (zh) 2009-03-31 2015-03-18 科德克希思公司 改良的内切葡聚糖酶
WO2010121933A1 (en) 2009-04-22 2010-10-28 Dsm Ip Assets B.V. Process for the production of a recombinant polypeptide of interest
EP2248893A1 (de) 2009-05-06 2010-11-10 Novozymes A/S DFPase-Enzyme aus Octopus Vulgaris
WO2010135624A2 (en) 2009-05-22 2010-11-25 Codexis, Inc. Engineered biosynthesis of fatty alcohols
EP2435561B1 (de) 2009-05-29 2018-08-08 Novozymes Inc. Verfahren zur verbesserung des abbaus oder der umwandlung von cellulosematerial
ES2534078T3 (es) 2009-06-02 2015-04-17 Novozymes Inc. Polipéptidos con actividad de celobiohidrolasa y polinucleótidos que codifican los mismos
HUE055413T2 (hu) 2009-06-22 2021-11-29 Codexis Inc Ketoreduktáz-közvetített sztereoszelektív útvonal alfa-klóralkoholokhoz
WO2010151787A1 (en) 2009-06-26 2010-12-29 Novozymes North America, Inc. Heat-stable carbonic anhydrases and their use
US8216815B2 (en) 2009-06-30 2012-07-10 Codexis, Inc. Production of fatty alcohols with fatty alcohol forming acyl-CoA reductases (FAR)
CA2767169A1 (en) 2009-07-07 2011-01-13 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011009700A1 (en) 2009-07-22 2011-01-27 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
CN102498126A (zh) 2009-08-07 2012-06-13 诺维信公司 用于产生甜蛋白的方法
EP2467475A1 (de) 2009-08-19 2012-06-27 Danisco US Inc. Kombinatorische glucoamylasevarianten mit verbesserter spezifischer aktivität und/oder wärmestabilität
AR077942A1 (es) 2009-08-19 2011-10-05 Danisco Variantes de glucoamilasa
US8409830B2 (en) 2009-08-21 2013-04-02 Novozymes A/S Polypeptides having isoamylase activity and methods of use
US8741611B2 (en) 2009-09-01 2014-06-03 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
DK3269804T3 (da) 2009-09-17 2020-11-23 Novozymes Inc Polypeptider med cellulolyseforbedrende aktivitet og polynukleotider, som koder for dem
EP2478095A1 (de) 2009-09-18 2012-07-25 Novozymes Inc. Polypeptide mit beta-glucosidase-aktivität und dafür kodierende polynukleotide
EP2480650B1 (de) 2009-09-25 2017-03-22 Novozymes A/S Subtilasevarianten
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
WO2011041397A1 (en) 2009-09-29 2011-04-07 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2775347A1 (en) 2009-09-29 2011-04-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
BR112012007375A2 (pt) 2009-09-30 2016-11-22 Novozymes As polipeptídeo isolado, polinucleotídeo isolado, métodos para produzir um polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada, molécula de rna inibitória de filamento duplo, e, composição detergente
DK2483415T3 (en) 2009-09-30 2015-02-09 Codexis Inc RECOMBINANT C1 B-glucosidase FOR MANUFACTURE OF sugars from cellulosic BIOMASS
WO2011039319A1 (en) 2009-09-30 2011-04-07 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011050037A1 (en) 2009-10-23 2011-04-28 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
DK2496692T3 (en) 2009-11-06 2016-06-27 Novozymes Inc POLYPEPTIDES WITH xylanase AND POLYNUCLEOTIDES ENCODING THEM
CN103068976A (zh) 2009-11-06 2013-04-24 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
DK3222716T3 (da) 2009-11-06 2020-11-16 Novozymes Inc Sammensætninger til saccharificering af cellulosemateriale
ES2455269T3 (es) 2009-11-25 2014-04-15 Codexis, Inc. Variantes de beta-glucosidasa recombinante para la producción de azúcares solubles de biomasa celulósica
US8652813B2 (en) 2009-11-25 2014-02-18 Codexis, Inc. Recombinant Thermoascus aurantiacus β-glucosidase variants
CA2782154C (en) 2009-11-30 2018-10-16 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CN102869770B (zh) 2009-11-30 2015-12-16 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
CA2782036C (en) 2009-12-01 2019-01-15 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
US8951770B2 (en) 2009-12-09 2015-02-10 Novozymes A/S GH8 xylanase variants
WO2013003290A1 (en) 2011-06-28 2013-01-03 Codexis, Inc. Protein variant generation by region shuffling
ES2668202T3 (es) 2009-12-11 2018-05-17 Novozymes A/S Variantes de proteasa
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
US20120220513A1 (en) 2009-12-29 2012-08-30 Novozymes A/S Polypeptides Having Detergency Enhancing Effect
CN102884183B (zh) 2010-01-04 2015-09-16 诺维信公司 趋于钙耗竭和酸性pH的α-淀粉酶的稳定化
US8617856B2 (en) 2010-01-07 2013-12-31 Wisconsin Alumni Research Foundation Fatty acid-producing hosts
CA2789301A1 (en) 2010-02-11 2011-08-18 Dsm Ip Assets B.V. Host cell capable of producing enzymes useful for degradation of lignocellulosic material
JP5833576B2 (ja) 2010-02-25 2015-12-16 ノボザイムス アクティーゼルスカブ リゾチームの変異体及びそれをコードするポリヌクレオチド
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
WO2011109524A2 (en) 2010-03-03 2011-09-09 Novozymes, Inc. Xylanase variants and polynucleotides encoding same
US20110229921A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
CN102917600B (zh) 2010-03-26 2015-07-08 诺维信公司 热稳定性肌醇六磷酸酶变体
WO2011123450A1 (en) 2010-03-31 2011-10-06 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
CA2795806C (en) 2010-04-14 2019-01-08 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
EP2576804B1 (de) 2010-05-28 2016-12-14 Codexis, Inc. Pentosefermentierung durch einen rekombinanten mikroorganismus
WO2011153317A1 (en) 2010-06-04 2011-12-08 Novozymes, Inc. C4 dicarboxylic acid production in filamentous fungi
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
IN2013CN00459A (de) 2010-06-21 2015-07-03 Novozymes Inc
AU2011271094B2 (en) 2010-06-21 2015-01-22 Novozymes, Inc. Aspergillus aculeatus derived polypeptides having C4-dicarboxylic acid transporter activity and polynucleotides encoding same
WO2011161206A1 (en) 2010-06-25 2011-12-29 Novozymes A/S Polynucleotides having leader sequence function
US9551714B2 (en) 2010-06-25 2017-01-24 Abbott Laboratories Materials and methods for assay of anti-hepatitis C virus (HCV) antibodies
EP2585602A1 (de) 2010-06-25 2013-05-01 Novozymes A/S Polynukleotide mit promoterwirkung
CN103068989B (zh) 2010-06-25 2015-09-09 诺维信公司 具有启动子活性的多核苷酸
US8574878B2 (en) 2010-06-28 2013-11-05 Behnaz Behrouzian Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
EP2588604B1 (de) 2010-06-30 2016-06-29 Novozymes, Inc. Polypeptide mit beta-glucosidase-aktivität und dafür kodierende polynukleotide
CA2803222A1 (en) 2010-07-01 2012-01-05 Dsm Ip Assets B.V. A method for the production of a compound of interest
WO2012013197A2 (en) 2010-07-30 2012-02-02 Aalborg Universitet Aspergillus encoding beta-glucosidases and nucleic acids encoding same
WO2012021401A1 (en) 2010-08-12 2012-02-16 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof
BR112013003466A2 (pt) 2010-08-17 2016-11-22 Carlsberg Breweries As método de melhorar a estabilidade coloidal da cerveja, e, uso de snapalysin
ES2623288T3 (es) 2010-08-20 2017-07-10 Codexis, Inc. Uso de proteínas de la familia de glicólido hidrolasa 61 en el procesamiento de celulosa
CN107299095B (zh) 2010-08-24 2021-05-11 诺维信公司 热稳定性Persephonella碳酸酐酶及其用途
US9267126B2 (en) 2010-08-30 2016-02-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2012030858A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having hemicellulolytic activity and polynucleotides encoding same
WO2012030811A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US8629325B2 (en) 2010-08-30 2014-01-14 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2012030849A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US9303074B2 (en) 2010-08-30 2016-04-05 Novoyzmes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2616483A1 (de) 2010-09-16 2013-07-24 Novozymes A/S Lysozyme
EP2622070B1 (de) 2010-09-30 2016-08-03 Novozymes, Inc. Polypeptidvarianten mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
EP2622068B1 (de) 2010-09-30 2016-07-20 Novozymes, Inc. Polypeptidvarianten mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
MX2013002586A (es) 2010-10-01 2013-03-21 Novozymes Inc Variantes de beta-glucosidasa y polinucleotidos que codifican las mismas.
RU2583293C2 (ru) 2010-10-01 2016-05-10 Новозимс А/С Полипептиды, обладающие эндопептидазной активностью, и кодирующие их полинуклеотиды
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
MX2013004353A (es) 2010-10-29 2013-06-28 Novozymes Inc Produccion recombinante de n-propanol e isopropanol.
EP2632943A1 (de) 2010-10-29 2013-09-04 Novozymes A/S Polypeptide mit succinyl-coa:acetacetat-transferaseaktivität und dafür kodierende polynukleotide
DK2635689T3 (en) 2010-11-02 2015-07-06 Novozymes Inc METHODS OF PREPARATION OF cellulosic material WITH A GH61-POLYPEPTIDE
EP2635594B1 (de) 2010-11-04 2017-01-11 Novozymes Inc. Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide
EP2637515B1 (de) 2010-11-08 2017-09-06 Novozymes A/S Polypeptide mit glucoamylaseaktivität und dafür codierende polynukleotide
DK2638154T3 (da) 2010-11-08 2017-01-02 Novozymes As Polypeptider med glucoamylaseaktivitet og polynukleotider, der koder for dem
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
BR112013011442A2 (pt) 2010-11-12 2020-08-11 Novozymes A/S polipeptídeo isolado, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, método de produção do polipeptídeo, composição, uso do polipeptídeo ou da composição, métodos de redução do teor de componentes contendo fósforo em um óleo comestível, e para desengomagem de uma composição de óleo
BR112013009026A2 (pt) 2010-11-12 2016-07-12 Novozymes Inc polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula
WO2012068509A1 (en) 2010-11-18 2012-05-24 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
DK2646558T3 (en) 2010-11-30 2016-10-03 Novozymes Inc Promoters for expression of genes in a fungal cell
US8927235B2 (en) 2010-12-06 2015-01-06 Novozymes A/S Methods of hydrolyzing oligomers in hemicellulosic liquor
AU2011338504B2 (en) 2010-12-07 2015-01-22 Vnomics Corp. System and method for measuring and reducing vehicle fuel waste
WO2012083081A1 (en) 2010-12-16 2012-06-21 Novozymes, Inc. Promoters for expressing genes in a fungal cell
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
EP2668266B1 (de) 2011-01-26 2018-01-03 Novozymes A/S Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US9157075B2 (en) 2011-01-26 2015-10-13 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
DK2668270T3 (en) 2011-01-26 2019-01-07 Novozymes Inc Polypeptides with cellobiohydrolase activity and polynucleotides encoding them
DK2670853T3 (en) 2011-01-31 2017-08-28 Novozymes North America Inc Process for enzymatic refining of pretreated cellulosic material for sugars
EP2678352B1 (de) 2011-02-23 2017-12-06 Novozymes, Inc. Polypeptide mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
CN103797114A (zh) 2011-02-23 2014-05-14 杜邦营养生物科学有限公司 生产能够水解叶绿素或叶绿素衍生物的重组酶的方法
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
CN103608461B (zh) 2011-03-09 2016-08-03 诺维信公司 增加多肽的纤维素分解增强活性的方法
WO2012122477A1 (en) 2011-03-10 2012-09-13 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012123429A1 (en) 2011-03-11 2012-09-20 Dsm Ip Assets B.V. Vector-host system
US9879294B2 (en) 2011-03-25 2018-01-30 Novozymes A/S Methods for degrading or converting cellulosic material
US8663962B2 (en) 2011-03-30 2014-03-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
WO2012135719A1 (en) 2011-03-31 2012-10-04 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
DK2702153T3 (en) 2011-04-28 2019-03-18 Novozymes Inc Polypeptides with endoglucanase activity and polynucleotides encoding them
DK2702162T3 (da) 2011-04-29 2020-05-18 Novozymes Inc Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale
EP2710132A1 (de) 2011-05-19 2014-03-26 Novozymes, Inc. Verfahren zur verstärkung des abbaus von zellulosestoffen mit chitinbindenden proteinen
EP2710133A1 (de) 2011-05-19 2014-03-26 Novozymes, Inc. Verfahren zur verstärkung des abbaus von zellulosestoffen mit chitinbindenden proteinen
EP2527448A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Gleichzeitige standortspezifische Integrationen von mehreren Genkopien in faserige Pilze
EP2527432A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Bidirektionaler Cytosin-Deaminase-codierender Selektionsmarker
CN103620029B (zh) 2011-06-24 2017-06-09 诺维信公司 具有蛋白酶活性的多肽和编码它们的多核苷酸
EP2726500B1 (de) 2011-06-30 2019-03-20 Novozymes A/S Verfahren zum screening von alpha-amylasen
EP3421595B1 (de) 2011-06-30 2020-10-07 Novozymes A/S Alpha-amylase-varianten
US8778652B2 (en) 2011-06-30 2014-07-15 Codexis, Inc. Pentose fermentation by a recombinant microorganism
MX337984B (es) 2011-07-06 2016-03-30 Novozymes As Variantes de alfa amilasa y polinucleotidos que codifican la misma.
CN103827298A (zh) 2011-07-15 2014-05-28 诺维信公司 脂肪酶变体及其编码多核苷酸
CN109022518A (zh) 2011-07-22 2018-12-18 诺维信北美公司 用于预处理纤维素材料和改进其水解的方法
BR112014002401B1 (pt) 2011-08-04 2021-08-03 Novozymes A/S Célula hospedeira transgênica de fungo filamentoso, métodos para produzir um polipeptídeo e uma proteína, e, construto de ácido nucleico ou um vetor de expressão
EP2739728B1 (de) 2011-08-04 2017-07-12 Novozymes A/S Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
EP2742129B1 (de) 2011-08-10 2017-08-02 Novozymes A/S Polypeptide mit peroxygenase-aktivität und dafür kodierende polynukleotide
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9506044B2 (en) 2011-08-10 2016-11-29 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9487761B2 (en) 2011-08-10 2016-11-08 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2744898A1 (de) 2011-08-15 2014-06-25 Novozymes A/S Polypeptide mit cellulase-aktivität und dafür kodierende polynukleotide
BR112014003444A2 (pt) 2011-08-19 2017-03-14 Novozymes Inc célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico
US20140295027A1 (en) 2011-08-19 2014-10-02 Novozymes A/S Polypeptides Having Protease Activity
WO2013028701A1 (en) 2011-08-22 2013-02-28 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
EP2748314B1 (de) 2011-08-24 2016-12-28 Novozymes, Inc. Cellulolytische enzymzusammensetzungen aus aspergillus fumigatus und verwendungen davon
WO2013028912A2 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
BR112014004188A2 (pt) 2011-08-24 2017-03-21 Novozymes Inc método para obter transformantes positivos de uma célula hospedeira fúngica filamentosa, célula hospedeira fúngica filamentosa, método para produzir múltiplos polipeptídeos recombinantes, e, construto em tandem
DK2748305T3 (en) 2011-08-24 2017-02-06 Novozymes Inc CELLULOLYTIC ENZYME COMPOSITIONS AND APPLICATIONS THEREOF
CA2846690A1 (en) 2011-08-26 2013-03-07 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CN103930543B (zh) 2011-09-06 2020-11-27 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
EP2753640B1 (de) 2011-09-08 2016-03-09 Codexis, Inc. Biokatalysatoren und verfahren zur synthese von substituierten lactamen
CA2847236A1 (en) 2011-09-09 2013-03-14 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2756091A1 (de) 2011-09-13 2014-07-23 Novozymes North America, Inc. Verfahren zur hydrolyse und fermentierung von zellulosematerial
US20140308705A1 (en) 2011-09-20 2014-10-16 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
DK2760885T3 (en) 2011-09-30 2017-10-30 Novozymes Inc CHEMICAL POLYPEPTIDES WITH BETA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
WO2013044867A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2751261B1 (de) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenasevarianten und dafür kodierende polynukleotide
WO2013052604A1 (en) 2011-10-04 2013-04-11 University Of Florida Research Foundation, Inc. Variants of glycerol dehydrogenase having d-lactate dehydrogenase activity and uses thereof
US9353362B2 (en) 2011-10-11 2016-05-31 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
HUE039835T2 (hu) 2011-10-17 2019-02-28 Novozymes As Alfa-amiláz variánsok és az azokat kódoló polinukleotidok
CA3253390A1 (en) 2011-10-17 2025-06-17 Novozymes A/S Variants of alpha-amylase and the polynucleotides encoding them
US9249418B2 (en) 2011-10-31 2016-02-02 Bp Corporation North America Inc. Use of plant promoters in filamentous fungi
US20130109055A1 (en) 2011-10-31 2013-05-02 Bp Corporation North America Inc. Use of mammalian promoters in filamentous fungi
US10308921B2 (en) 2011-10-31 2019-06-04 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2780449B1 (de) 2011-11-18 2018-04-11 Novozymes, Inc. Polypeptide mit beta-glucosidase-aktivität, beta-xylosidase-aktivität oder beta-glucosidase- und beta-xylosidase-aktivität sowie dafür kodierende polynukleotide
CN103958672A (zh) 2011-11-21 2014-07-30 诺维信股份有限公司 Gh61多肽变体以及编码所述变体的多核苷酸
DK2782998T3 (en) 2011-11-22 2018-04-16 Novozymes Inc POLYPEPTIDES WITH BETA-XYLOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
JP6105615B2 (ja) 2011-11-25 2017-03-29 ノボザイムス アクティーゼルスカブ リゾチーム活性を有するポリペプチドおよびそれをコードするポリヌクレオチド
US9624481B2 (en) 2011-12-01 2017-04-18 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
US9169469B2 (en) 2011-12-02 2015-10-27 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9404093B2 (en) 2011-12-02 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
JP6378089B2 (ja) 2011-12-09 2018-08-22 ダニスコ・ユーエス・インク 微生物におけるタンパク質産生のための、B.ズブチリス(B.subtilis)からのリボソームプロモーター
WO2013087027A1 (en) 2011-12-16 2013-06-20 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
WO2013091547A1 (en) 2011-12-19 2013-06-27 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
DK2794869T3 (en) 2011-12-20 2018-01-02 Novozymes Inc CELLOBIO HYDROLASE VARIABLES AND POLYNUCLEOTIDES CODING THEM
US9611462B2 (en) 2011-12-20 2017-04-04 Codexis, Inc. Endoglucanase 1B (EG1B) variants
ES2667318T3 (es) 2011-12-28 2018-05-10 Novozymes A/S Polipéptidos con actividad de proteasa
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
US9801398B2 (en) 2012-01-26 2017-10-31 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
DK2623586T3 (da) 2012-02-03 2017-11-13 Procter & Gamble Sammensætninger og fremgangsmåder til overfladebehandling med lipaser
EP4570895A3 (de) 2012-02-03 2026-01-14 Novozymes A/S Lipasevarianten und polynukleotide zu deren codierung
PT2817325T (pt) 2012-02-20 2019-10-01 Novozymes As Polipéptidos que têm atividade da endoglucanase e polinucleotídeos codificando mesmos
WO2013142770A1 (en) 2012-03-23 2013-09-26 Codexis, Inc. Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
EP2834353B1 (de) 2012-04-02 2017-07-19 Novozymes A/S Lipasevarianten und polynukleotide zu deren codierung
EP2841570B1 (de) 2012-04-23 2017-12-20 Novozymes A/S Polypeptide mit glucuronyl-esteraseaktivität und polynukleotide zur codierung davon
US9446102B2 (en) 2012-04-23 2016-09-20 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
CN104245926B (zh) 2012-04-27 2021-05-07 诺维信股份有限公司 Gh61多肽变体以及编码其的多核苷酸
CN113201519A (zh) 2012-05-07 2021-08-03 诺维信公司 具有黄原胶降解活性的多肽以及编码其的核苷酸
WO2013169725A2 (en) 2012-05-08 2013-11-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
WO2013170050A1 (en) 2012-05-11 2013-11-14 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
EP2855659A1 (de) 2012-05-31 2015-04-08 Novozymes A/S Verbesserte auswahl bei pilzen
EP2855670A2 (de) 2012-05-31 2015-04-08 Novozymes A/S Polypeptide mit organophosphor-hydrolase-aktivität
US8980578B2 (en) 2012-06-11 2015-03-17 Codexis, Inc. Fungal beta-xylosidase variants
US20150197760A1 (en) 2012-06-19 2015-07-16 Dsm Ip Assets B.V. Promoters for expressing a gene in a cell
MX364390B (es) 2012-06-20 2019-04-25 Novozymes As Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes.
CN104471048B (zh) 2012-07-12 2018-11-16 诺维信公司 具有脂肪酶活性的多肽及编码它的多核苷酸
EP3327112B1 (de) 2012-07-19 2020-02-12 DSM IP Assets B.V. Agse-armer stamm
TR201809053T4 (tr) 2012-08-16 2018-07-23 Bangladesh Jute Res Institute Macrophomina phaseolina'dan elde edilen pektin parçalama enzimleri ve bunların kullanımları.
TR201815368T4 (tr) 2012-08-16 2018-11-21 Bangladesh Jute Res Institute Macrophomina Phaseolina'dan elde edilen selüloz ve hemiselüloz parçalama enzimleri ve bunların kullanımları.
US9828595B2 (en) 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
WO2014028833A1 (en) 2012-08-17 2014-02-20 Novozymes A/S Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
MX2015002099A (es) 2012-08-22 2015-05-11 Dupont Nutrition Biosci Aps Variantes que tienen actividad glucoamilasa.
US9315791B2 (en) 2012-08-22 2016-04-19 Novozymes A/S Metalloproteases from alicyclobacillus
MX2015002211A (es) 2012-08-22 2015-05-08 Novozymes As Metaloproteasa de exiguobacterium.
AU2013311668B2 (en) 2012-09-05 2019-02-28 Novozymes A/S Polypeptides having protease activity
US20140073022A1 (en) 2012-09-10 2014-03-13 Wisconsin Alumni Research Foundation Production of polyhydroxyalkanoates with a defined composition from an unrelated carbon source
BR112015005884A2 (pt) 2012-09-19 2017-08-08 Novozymes Inc E Novozymes As processos para degradação de um material celulósico, para produção de um produto da fermentação, e de fermentação de um material celulósico, composição, e, formulação de caldo inteiro ou composição de cultura de células
EP2898076B1 (de) 2012-09-19 2018-03-07 DSM IP Assets B.V. Zellmodifizierungsverfahren
EP3586610B1 (de) 2012-10-08 2024-09-25 Novozymes A/S Polypeptide mit verstärkter celluloseabbauender wirkung und polynukleotide zur codierung davon
CN104718287B (zh) 2012-10-12 2018-02-06 诺维信公司 具有过氧合酶活性的多肽
EP2906685B1 (de) 2012-10-12 2018-08-15 Novozymes A/S Polypeptide mit peroxygenaseaktivität
EP2906689B1 (de) 2012-10-12 2018-12-12 Novozymes A/S Polypeptide mit peroxygenaseaktivität
US9453207B2 (en) 2012-10-12 2016-09-27 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056916A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
US9404094B2 (en) 2012-10-12 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity
EP2906686B1 (de) 2012-10-12 2018-08-29 Novozymes A/S Polypeptide mit peroxygenaseaktivität
WO2014066141A2 (en) 2012-10-24 2014-05-01 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
US9611515B2 (en) 2012-11-20 2017-04-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
EP2925774B8 (de) 2012-11-29 2018-03-07 The Texas A&M University System Technische herstellung einer konformationalen variante von occidiofungin mit verbesserter hemmungsaktivität gegen pilzspezies
US20150307871A1 (en) 2012-12-07 2015-10-29 Novozymes A/S Method for generating site-specific mutations in filamentous fungi
US20150368627A1 (en) 2012-12-11 2015-12-24 Novozymes A/S Polypeptides Having Phospholipase C Activity and Polynucleotides Encoding Same
US9765373B2 (en) 2012-12-14 2017-09-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2772032T3 (es) 2012-12-17 2020-07-07 Novozymes As Alfa-amilasas y polinucleótidos que las codifican
WO2014099798A1 (en) 2012-12-19 2014-06-26 Novozymes A/S Polypeptides having cellulolytic enhancinc activity and polynucleotides encoding same
US9551042B2 (en) 2012-12-21 2017-01-24 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP2935609A1 (de) 2012-12-21 2015-10-28 Novozymes, Inc. Verfahren zur herstellung von heterologen polypeptiden in mutanten von trichoderma
SG11201504752YA (en) 2012-12-21 2015-07-30 Codexis Inc Engineered biocatalysts and methods for synthesizing chiral amines
EP2938628A4 (de) 2012-12-24 2016-10-19 Novozymes As Polypeptide mit endoglucanaseaktivität und polynukleotide zur codierung davon
EP3321360A3 (de) 2013-01-03 2018-06-06 Novozymes A/S Alpha-amylase-varianten und polynukleotide zur codierung davon
CN105051180B (zh) 2013-01-18 2020-06-12 科德克希思公司 用于碳青霉烯类合成的工程化的生物催化剂
EP3686280B1 (de) 2013-02-04 2022-06-22 DSM IP Assets B.V. Kohlenhydratabbauendes polypeptid und verwendungen davon
MX2015010078A (es) 2013-02-06 2016-01-25 Novozymes As Uso de polipeptidos con actividad proteasa en alimentos para animales.
US9617573B2 (en) 2013-02-28 2017-04-11 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
CN105164254B (zh) 2013-03-08 2019-06-28 诺维信公司 纤维二糖水解酶变体和编码它们的多核苷酸
KR102178036B1 (ko) 2013-03-15 2020-11-13 디에스엠 아이피 어셋츠 비.브이. 핵산 분해를 위한 호열성 뉴클레아제의 용도
WO2014145768A2 (en) 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi
EP3533866A1 (de) 2013-03-21 2019-09-04 Novozymes A/S Polypeptide mit phospholipase-a-activität und polynucleotide zu deren codierung
US9631164B2 (en) 2013-03-21 2017-04-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP2981610A1 (de) 2013-04-05 2016-02-10 Université du Luxembourg Biotechnologische herstellung von itaconsäure
WO2014170218A1 (en) 2013-04-18 2014-10-23 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
PL2986722T3 (pl) 2013-04-18 2019-10-31 Codexis Inc Skonstruowane polipeptydy amoniakoliazy fenyloalaniny
EP3372680B1 (de) 2013-04-30 2020-11-11 Novozymes A/S Glycoamylasevarianten und polynukleotide zur codierung davon
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US9556465B2 (en) 2013-05-10 2017-01-31 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
MX392247B (es) 2013-05-14 2025-03-24 Novozymes As Composiciones detergentes.
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
CN114634921B (zh) 2013-06-06 2024-09-10 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
JP2016523098A (ja) 2013-07-04 2016-08-08 ノボザイムス アクティーゼルスカブ 再付着防止効果を有するポリペプチドおよびそれをコードするポリヌクレオチド
WO2015004102A1 (en) 2013-07-09 2015-01-15 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015004241A2 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
DK3022300T3 (en) 2013-07-17 2018-10-22 Novozymes As : Pullulan chimeras and polynucleotides encoding them
CA2917690A1 (en) 2013-07-26 2015-01-29 Biomethodes Novel variant trichoderma reesei endoglucanases
US10010094B2 (en) 2013-08-15 2018-07-03 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
US9708630B1 (en) 2013-10-08 2017-07-18 Wisconsin Alumni Research Foundation Cells and methods for producing fatty alcohols
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
CN105518142B (zh) 2013-10-25 2020-07-28 诺维信公司 具有内切葡聚糖酶活性的多肽以及对其进行编码的多核苷酸
CN106232619B (zh) 2013-11-13 2022-09-09 科德克希思公司 工程化的亚胺还原酶和用于酮和胺化合物的还原胺化的方法
EP3074513A1 (de) 2013-11-26 2016-10-05 Novozymes A/S Enzymzusammensetzungen und verwendungen davon
EP2876156A1 (de) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neue Enzyme und Verfahren zur Herstellung von hydroxyliertem L-Lysin oder L-Ornithin und Analoga davon
WO2015079064A2 (en) 2013-11-29 2015-06-04 Novozymes A/S Peroxygenase variants
EP3077517B1 (de) 2013-12-02 2018-10-17 DSM IP Assets B.V. Eisstrukturierungsprotein
CN122012456A (zh) 2013-12-11 2026-05-12 诺维信公司 角质酶变体以及对其进行编码的多核苷酸
EP2886656A1 (de) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neues Enzym und Verfahren zur Herstellung von 4-hydroxylbenzylalkohol und Derivaten davon
EP3453757B1 (de) 2013-12-20 2020-06-17 Novozymes A/S Polypeptide mit proteaseaktivität und polynukleotide, die für diese kodieren
EP3097192B1 (de) 2014-01-22 2018-07-25 Novozymes A/S Pulluonasevarianten und polynukleotide zur codierung davon
EP3097112B1 (de) 2014-01-22 2020-05-13 Novozymes A/S Polypeptide mit lipaseaktivität und polynukleotide zur codierung davon
EP3113611A1 (de) 2014-03-05 2017-01-11 Novozymes A/S Formulierungen mit polymerem xyloglucan als ein träger landwirtschaftlich nützlicher wirkstoffe
EP3114276B1 (de) 2014-03-05 2019-01-16 Novozymes A/S Zusammensetzungen und verfahren zur funktionalisierung und verbindung von materialien
EP3113609B1 (de) 2014-03-05 2019-07-31 Novozymes A/S Verfahren zur verbesserung der eigenschaften von landwirtschaftlichen produkten nach der ernte
CN106062271A (zh) 2014-03-05 2016-10-26 诺维信公司 用于改进具有木葡聚糖内糖基转移酶的纤维素纺织材料的性质的组合物和方法
CN106062270A (zh) 2014-03-05 2016-10-26 诺维信公司 使用木葡聚糖内糖基转移酶改进非纤维素纺织材料的性质的组合物和方法
US10155935B2 (en) 2014-03-12 2018-12-18 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015150457A1 (en) 2014-04-01 2015-10-08 Novozymes A/S Polypeptides having alpha amylase activity
WO2015157656A1 (en) 2014-04-10 2015-10-15 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CN106164236B (zh) 2014-04-11 2021-02-02 诺维信公司 洗涤剂组合物
US10030215B2 (en) 2014-04-15 2018-07-24 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP3145536B1 (de) 2014-04-16 2021-10-27 Codexis, Inc. Manipulierte tyrosin-ammoniak-lyase
WO2015177153A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
WO2015177152A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
MX375798B (es) 2014-05-19 2025-03-07 Dsm Ip Assets Bv Endoproteasa específica para prolina.
AR100605A1 (es) 2014-05-27 2016-10-19 Novozymes As Métodos para la producción de lipasas
EP3149178B1 (de) 2014-05-27 2020-07-15 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
CA2950273C (en) 2014-05-30 2022-06-21 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
EP3152315B1 (de) 2014-06-06 2018-08-15 Novozymes A/S Enzymzusammensetzungen und ihre verwendungen
ES2712402T3 (es) 2014-06-25 2019-05-13 Novozymes As Variantes de xilanasa y polinucleótidos que las codifican
US9708587B2 (en) 2014-07-09 2017-07-18 Codexis, Inc. P450-BM3 variants with improved activity
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
US20170267980A1 (en) 2014-08-20 2017-09-21 Novozymes A/S Xyloglucan Endotransglycosylase variants and Polynucleotides Encoding Same
EP3189137A1 (de) 2014-09-05 2017-07-12 Novozymes A/S Kohlenhydratbindende modulvarianten und polynukleotide zur codierung davon
WO2016062875A2 (en) 2014-10-23 2016-04-28 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US10619145B2 (en) 2014-11-04 2020-04-14 Novozymes A/S Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed
WO2016079305A1 (en) 2014-11-20 2016-05-26 Novozymes A/S Alicyclobacillus variants and polynucleotides encoding same
CN107002050A (zh) 2014-11-25 2017-08-01 科德克希思公司 工程化亚胺还原酶和用于酮和胺化合物的还原胺化的方法
WO2016090059A1 (en) 2014-12-02 2016-06-09 Novozymes A/S Laccase variants and polynucleotides encoding same
EP3227442B1 (de) 2014-12-05 2022-02-16 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
US20180000076A1 (en) 2014-12-16 2018-01-04 Novozymes A/S Polypeptides Having N-Acetyl Glucosamine Oxidase Activity
MX383142B (es) 2014-12-19 2025-03-13 Novozymes As Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa.
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
CA2970638A1 (en) 2014-12-22 2016-06-30 Codexis, Inc. Human alpha-galactosidase variants
DK3242950T3 (da) 2015-01-06 2021-12-20 Dsm Ip Assets Bv Crispr-cas-system til en trådformet svampeværtscelle
DK3256577T3 (da) 2015-02-10 2020-09-14 Codexis Inc Ketoreduktase polypeptider til syntesen af chirale forbindelser
FI3739045T3 (fi) 2015-02-24 2024-11-13 Novozymes As Sellobiohydrolaasivariantteja ja niitä koodittavia polynukleotideja
EP3262161B1 (de) 2015-02-27 2021-06-30 Novozymes A/S Mutante wirtszellen zur herstellung von 3-hydroxypropionsäure
US10385352B2 (en) 2015-03-09 2019-08-20 Novozymes A/S Methods of introducing multiple expression constructs into a eukaryotic cell
US20180073017A1 (en) 2015-04-07 2018-03-15 Novozymes A/S Methods for selecting enzymes having enhanced activity
US20180355404A1 (en) 2015-04-07 2018-12-13 Novozymes A/S Methods for selecting enzymes having lipase activity
AR104205A1 (es) 2015-04-09 2017-07-05 Dsm Ip Assets Bv Fosfolipasa c
CN107531762A (zh) 2015-05-07 2018-01-02 科德克希思公司 青霉素g酰化酶
WO2016186948A1 (en) 2015-05-15 2016-11-24 Albert Einstein College Of Medicine, Inc. Gfp-derived fusion tags for protein expression
ES2929531T3 (es) 2015-05-22 2022-11-30 Dupont Nutrition Biosci Aps Acetolactato descarboxilasa
CN107532154B (zh) 2015-05-27 2022-09-27 国投生物科技投资有限公司 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸
AU2016273208B2 (en) 2015-06-02 2021-01-21 Dsm Ip Assets B.V. Use of ice structuring protein AFP19 expressed in filamentous fungal strains for preparing food
EP3310908B1 (de) 2015-06-16 2020-08-05 Novozymes A/S Polypeptide mit lipaseaktivität und polynukleotide zur codierung davon
US10676727B2 (en) 2015-06-18 2020-06-09 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
EP3313990A4 (de) 2015-06-26 2019-01-23 Novozymes A/S Bio-endbearbeitungssystem
AU2016282355B2 (en) 2015-06-26 2020-04-09 Novozymes A/S Method for producing a coffee extract
CA2987160C (en) 2015-07-01 2022-12-13 Novozymes A/S Methods of reducing odor
AU2016286612B2 (en) 2015-07-02 2021-01-28 Novozymes A/S Animal feed compositions and uses thereof
CN114292829A (zh) 2015-07-06 2022-04-08 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
JP6691558B2 (ja) 2015-07-07 2020-04-28 コデクシス, インコーポレイテッド 改善された活性を持つ新規のp450−bm3バリアント
CN108138153A (zh) 2015-07-24 2018-06-08 诺维信股份有限公司 具有阿拉伯呋喃糖苷酶活性的多肽以及编码它们的多核苷酸
WO2017019491A1 (en) 2015-07-24 2017-02-02 Novozymes Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
WO2017017292A1 (es) 2015-07-29 2017-02-02 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expresión de enzimas beta-xilosidasas recombinantes
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
US10933121B2 (en) 2015-09-02 2021-03-02 Dupont Nutrition Biosciences Aps Glycoside hydrolases and their use in preventing and/or treating a pathogenic infection in an animal
EP3344761A1 (de) 2015-09-04 2018-07-11 Novozymes A/S Verfahren zur hemmung von aa9-lytischer polysaccharid-monooxygenase-katalysierter inaktivierung von enzymzusammensetzungen
CA2991114A1 (en) 2015-09-17 2017-03-23 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
US10479984B2 (en) 2015-09-22 2019-11-19 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
WO2017060475A2 (en) 2015-10-07 2017-04-13 Novozymes A/S Polypeptides
EP3362574B1 (de) 2015-10-14 2021-07-07 Novozymes A/S Glycoamylasevarianten und polynukleotide zur codierung davon
CN108291212A (zh) 2015-10-14 2018-07-17 诺维信公司 多肽变体
US20180171318A1 (en) 2015-10-14 2018-06-21 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
WO2017075426A1 (en) 2015-10-30 2017-05-04 Novozymes A/S Polynucleotide constructs for in vitro and in vivo expression
US11001821B2 (en) 2015-11-24 2021-05-11 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP3384019B1 (de) 2015-12-01 2020-06-24 Novozymes A/S Verfahren zur herstellung von lipasen
BR112018011096A2 (pt) 2015-12-02 2018-12-04 Inst Nat De La Rech Agronomique Inra novos peptídeos que têm atividade antimicrobiana e nova enzima capaz de converter resíduo de configuração l em aminoácido de configuração d em um peptídeo
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
WO2017112847A1 (en) 2015-12-22 2017-06-29 Albumedix A/S Improved protein expression strains
CN108603185B (zh) 2015-12-30 2022-05-17 诺维信公司 酶变体以及编码它们的多核苷酸
US20210171927A1 (en) 2016-01-29 2021-06-10 Novozymes A/S Beta-glucanase variants and polynucleotides encoding same
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
US20190048413A1 (en) 2016-02-23 2019-02-14 Novozymes A/S Improved next-generation sequencing
BR112018067371A2 (pt) 2016-03-02 2019-01-15 Novozymes As variante de celobio-hidrolase, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, célula hospedeira recombinante, planta, parte de planta ou célula de planta transgênica, métodos para produção e para obtenção de uma variante de celobio-hidrolase, planta trangênica, e, processos para degradação de um material celulósico, para produção de um produto de fermentação e para fermentação de um material celulósico
FI3419991T3 (fi) 2016-03-04 2023-01-31 Modifioidut ribosomaaliset promoottorit proteiinien tuottamiseksi mikro-organismeissa
CN109072209A (zh) 2016-03-24 2018-12-21 诺维信公司 纤维二糖水解酶变体和编码其的多核苷酸
WO2017177153A1 (en) 2016-04-07 2017-10-12 Novozymes A/S Methods for selecting enzymes having protease activity
DK3445776T3 (da) 2016-04-19 2021-04-19 Novozymes As RLMA-inaktiveret filamentøs svampeværtscelle
US10626354B2 (en) 2016-04-29 2020-04-21 Novozymes A/S Detergent compositions and uses thereof
US20240218340A1 (en) 2016-05-03 2024-07-04 Novozymes A/S Enzyme Variants and Polynucleotides Encoding Same
KR102382489B1 (ko) 2016-05-05 2022-04-01 코덱시스, 인코포레이티드 페니실린 g 아실라제
JP6985295B2 (ja) 2016-05-09 2021-12-22 ノボザイムス アクティーゼルスカブ 向上した性能を有する変異体ポリペプチドおよびその使用
EP3246401A1 (de) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives Neue fettsäuredecarboxylase und deren verwendungen
AU2017269498A1 (en) 2016-05-24 2018-11-08 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
AU2017270269A1 (en) 2016-05-24 2018-11-15 Novozymes A/S Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity
CN109312321A (zh) 2016-05-24 2019-02-05 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
ES3014057T3 (en) 2016-05-24 2025-04-16 Novozymes As Gastric stable polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
IL263448B2 (en) 2016-06-09 2023-10-01 Codexis Inc Biological catalysts and methods for hydroxylation of chemical compounds
US10829748B2 (en) 2016-06-10 2020-11-10 Dsm Ip Assets B.V. Mutant lipase and use thereof
EP3471744A4 (de) 2016-06-15 2020-07-29 Codexis, Inc. Manipulierte beta-glucosidasen und glucosylierungsverfahren
US10421951B2 (en) 2016-06-22 2019-09-24 Wisconsin Alumni Research Foundation Gene construct encoding mutant thioesterase, mutant thioesterase encoded thereby, transformed host cell containing the gene construct, and method of using them to produce medium-chain fatty acids
ES2807212T3 (es) 2016-06-30 2021-02-22 Fornia Biosolutions Inc Nuevas fitasas y usos de las mismas
BR112018077458A2 (pt) 2016-06-30 2019-04-02 Danisco Us Inc. proteases aspárticas
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
CN109715794A (zh) 2016-07-05 2019-05-03 诺维信公司 果胶裂解酶变体以及编码它们的多核苷酸
EP3481959A1 (de) 2016-07-06 2019-05-15 Novozymes A/S Verbesserung eines mikroorganismus durch crispr-inhibition
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
MX2019000139A (es) 2016-07-08 2019-06-10 Novozymes As Polipeptidos que tienen actividad xilanasa y polinucleotidos que los codifican.
RU2752204C2 (ru) 2016-07-08 2021-07-23 Новозимс А/С Варианты ксиланазы и кодирующие их полинуклеотиды
CN109415708A (zh) 2016-07-13 2019-03-01 宝洁公司 食物芽孢杆菌脱氧核糖核酸酶变体及其用途
CN109790525A (zh) 2016-07-18 2019-05-21 诺维信公司 脂肪酶变体、编码其的多核苷酸及其用途
WO2018017792A1 (en) 2016-07-20 2018-01-25 Novozymes A/S Heat-stable metagenomic carbonic anhydrases and their use
FI3487996T3 (fi) 2016-07-21 2024-07-10 Novozymes As Seriiniproteaasivariantteja ja niitä koodittavia polynukleotideja
CN109661465A (zh) 2016-07-21 2019-04-19 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
WO2018015443A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Improved filamentous fungal host
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US11512300B2 (en) 2016-08-24 2022-11-29 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
EP3504330A1 (de) 2016-08-24 2019-07-03 Novozymes A/S Gh9-endoglucanase-varianten und polynukleotide zur codierung davon
WO2018037064A1 (en) 2016-08-24 2018-03-01 Henkel Ag & Co. Kgaa Detergent compositions comprising xanthan lyase variants i
AU2017317564B2 (en) 2016-08-24 2021-09-30 Henkel Ag & Co. Kgaa Detergent composition comprising GH9 endoglucanase variants I
WO2018038906A1 (en) 2016-08-26 2018-03-01 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
CN109563522A (zh) 2016-09-15 2019-04-02 诺维信公司 真菌宿主细胞中dna片段的基因组整合
US11578316B2 (en) 2016-09-16 2023-02-14 Dupont Nutrition Biosciences Aps Acetolactate decarboxylase variants having improved specific activity
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
EP3541954A1 (de) 2016-11-21 2019-09-25 Novozymes A/S Durch hefezellenextrakt unterstützte konstruktion von dna-molekülen
AU2017380488B2 (en) 2016-12-21 2023-09-14 Novozymes A/S Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof
KR102696584B1 (ko) 2017-01-05 2024-08-19 코덱시스, 인코포레이티드 페니실린 g 아실라아제
RU2019123965A (ru) 2017-02-01 2021-02-01 Дзе Проктер Энд Гэмбл Компани Очищающие композиции, содержащие варианты амилазы
EP3577219B1 (de) 2017-02-01 2023-08-23 Novozymes A/S Alpha-amylase varianten
KR20260006703A (ko) 2017-02-03 2026-01-13 테이트 앤드 라일 솔루션스 유에스에이 엘엘씨 조작된 글리코실트랜스퍼라제 및 스테비올 글리코시드 글루코실화 방법
AU2018217495B2 (en) 2017-02-13 2021-03-04 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
MX2019009551A (es) 2017-02-20 2020-01-30 Novozymes As Enzima lipolitica para usarse en horneado.
CN110505903A (zh) 2017-03-06 2019-11-26 杜邦营养生物科学有限公司 新型真菌岩藻糖苷酶及其在预防和/或治疗动物病原体感染中的用途
EP3596199A1 (de) 2017-03-13 2020-01-22 DSM IP Assets B.V. Transkriptioneller regulator-defizienz-stamm mit zweikernigem zink-cluster
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
WO2018172155A1 (en) 2017-03-23 2018-09-27 Novozymes A/S Improved filamentous fungal host cells
CN110651040A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
CN110651041A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
EP3601549B1 (de) 2017-03-31 2026-07-01 Novozymes A/S Polypeptide mit dnase-aktivität
US11149233B2 (en) 2017-03-31 2021-10-19 Novozymes A/S Polypeptides having RNase activity
EP3606936B1 (de) 2017-04-03 2021-10-20 Novozymes A/S Verfahren zur rückgewinnung
CN110651029B (zh) 2017-04-04 2022-02-15 诺维信公司 糖基水解酶
WO2018185152A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptide compositions and uses thereof
EP3607039A1 (de) 2017-04-04 2020-02-12 Novozymes A/S Polypeptide
BR112019021223A2 (pt) 2017-04-11 2020-04-28 Novozymes A/S variante de glucoamilase, métodos para aumentar a atividade de hidrólise de amido em bruto de uma glucoamilase e para produzir uma variante de glucoamilase, composição, uso de uma variante de glucoamilase, processos para produzir um produto de fermentação e para produzir um produto de xarope, polinucleotídeo codificando a variante de glucoamilase, construto de ácido nucleico, vetor de expressão, e, célula hospedeira.
JP7045725B2 (ja) 2017-04-27 2022-04-01 コデクシス, インコーポレイテッド ケトレダクターゼポリペプチドおよびポリヌクレオチド
WO2018202846A1 (en) 2017-05-05 2018-11-08 Novozymes A/S Compositions comprising lipase and sulfite
EP3622064B1 (de) 2017-05-08 2025-05-14 Novozymes A/S Mannanase-varianten und dafür codierende polynukleotide
EP3401385A1 (de) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Tensidzusammensetzungen enthaltend polypeptide enthaltend eine carbohydrate binding domain
CA3058095A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
CA3062550A1 (en) 2017-05-08 2018-11-15 Codexis, Inc. Engineered ligase variants
WO2018224035A1 (en) 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
WO2018231462A1 (en) 2017-06-14 2018-12-20 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
EP4026908A1 (de) 2017-06-20 2022-07-13 Albumedix Ltd Verbesserte proteinexpressionsstämme
EP3642339B1 (de) 2017-06-22 2025-09-10 Novozymes A/S Xylanasevarianten und polynukleotide zur codierung davon
EP3645713A4 (de) 2017-06-27 2021-06-30 Codexis, Inc. Penicillin-g-acylasen
DK3645555T3 (da) 2017-06-28 2022-03-07 Novozymes As Polypeptider med trehalaseaktivitet og polynukleotider, der koder for disse
JP2020530267A (ja) 2017-06-30 2020-10-22 コデクシス, インコーポレイテッド T7 rnaポリメラーゼバリアント
KR102773542B1 (ko) 2017-06-30 2025-02-25 코덱시스, 인코포레이티드 T7 rna 폴리머라제 변이체
KR102683528B1 (ko) 2017-07-24 2024-07-10 노보자임스 에이/에스 습식 제분에서의 gh5 및 gh30
SG11202000775SA (en) 2017-07-28 2020-02-27 Univ Princeton Fusion tags for recombinant protein expression
US10081800B1 (en) 2017-08-03 2018-09-25 Fornia Biosolutions, Inc. Lactonase enzymes and methods of using same
CA3070281A1 (en) 2017-08-08 2019-02-14 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
EP3673056A1 (de) 2017-08-24 2020-07-01 Henkel AG & Co. KGaA Waschmittelzusammensetzung mit gh9-endoglucanasevarianten ii
CN111344404A (zh) 2017-08-24 2020-06-26 诺维信公司 黄原胶裂解酶变体以及编码其的多核苷酸
WO2019038058A1 (en) 2017-08-24 2019-02-28 Novozymes A/S GH9 ENDOGLUCANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SUCH VARIANTS
US20210130744A1 (en) 2017-08-24 2021-05-06 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase variants ii
US12702147B2 (en) 2017-08-30 2026-08-11 The Fynder Group, Inc. Edible foodstuffs and bio reactor design
US11464251B2 (en) * 2017-08-30 2022-10-11 The Fynder Group, Inc. Edible foodstuffs and bio reactor design
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
CN111050566A (zh) 2017-09-01 2020-04-21 诺维信公司 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途
US20200196633A1 (en) 2017-09-01 2020-06-25 Novozymes A/S Animal Feed Additives Comprising Polypeptide Having Protease Activity and Uses Thereof
PL3688149T3 (pl) 2017-09-26 2025-03-24 Bunge Global Innovation, Llc. Enzymatyczne usuwanie substratów chlorofilowych z olejów na bazie triacyloglicerolu
CN118910005A (zh) 2017-09-27 2024-11-08 诺维信公司 脂肪酶变体和包含此类脂肪酶变体的微囊组合物
MX2020003779A (es) 2017-09-27 2020-08-03 Procter & Gamble Composiciones detergentes que comprenden lipasas.
CN111373036A (zh) 2017-10-02 2020-07-03 诺维信公司 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
PL3476936T3 (pl) 2017-10-27 2022-04-11 The Procter & Gamble Company Kompozycje detergentu zawierające odmiany polipeptydowe
WO2019081724A1 (en) 2017-10-27 2019-05-02 Novozymes A/S VARIANTS OF DNASE
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
SG11202003094PA (en) 2017-11-07 2020-05-28 Codexis Inc Transglutaminase variants
EP3707252A1 (de) 2017-11-10 2020-09-16 Novozymes A/S Temperaturempfindliches cas9-protein
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
EP3485734A1 (de) 2017-11-21 2019-05-22 Technische Universität München Verfahren zur herstellung von lebensmittelprodukten mit roggen
EP3488854A1 (de) 2017-11-22 2019-05-29 Technische Universität München Verfahren zur herstellung von xyloglucan-oligosacchariden
US11725197B2 (en) 2017-12-04 2023-08-15 Novozymes A/S Lipase variants and polynucleotides encoding same
AU2018383752B2 (en) 2017-12-13 2025-01-30 Codexis, Inc. Carboxyesterase polypeptides for amide coupling
US11408009B2 (en) 2017-12-18 2022-08-09 Whitehead Institute For Biomedical Research Host cell expression of 4-hydroxyphenylacetaldehyde synthase for production of salidroside, icariside D2, and precursors
EP3502242A1 (de) 2017-12-20 2019-06-26 Technische Universität München Neue xylanase mit verbesserter thermostabilität und gesteigerter enzymaktivität auf arabinoxylan
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
US20210123033A1 (en) 2018-02-08 2021-04-29 Novozymes A/S Lipases, Lipase Variants and Compositions Thereof
US20210071155A1 (en) 2018-02-08 2021-03-11 Novozymes A/S Lipase Variants and Compositions Thereof
EP3530744A1 (de) 2018-02-23 2019-08-28 University of Limerick Polypeptid mit xylanase- und/oder cellulase-aktivität
CN112105740A (zh) 2018-02-23 2020-12-18 诺维信公司 真菌宿主中的长链非编码rna表达
CN112004931A (zh) 2018-03-26 2020-11-27 诺维信公司 真菌伴侣蛋白
WO2019185726A1 (en) 2018-03-29 2019-10-03 Novozymes A/S Mannanase variants and polynucleotides encoding same
CN112105729B (zh) 2018-04-09 2024-05-14 诺维信公司 具有α-淀粉酶活性的多肽以及编码它们的多核苷酸
US11566239B2 (en) 2018-04-19 2023-01-31 Novozymes A/S Stabilized cellulase variants
CN112272701B (zh) 2018-04-19 2024-05-14 诺维信公司 稳定化的纤维素酶变体
WO2019219904A2 (en) 2018-05-18 2019-11-21 Dsm Ip Assets B.V. Mutant lipase and use thereof
US20230080079A1 (en) 2018-05-18 2023-03-16 Dsm Ip Assets B.V. Mutant lipase and use thereof
EP3807409A4 (de) 2018-06-12 2022-08-03 Codexis, Inc. Manipulierte tyrosin-ammoniak-lyase
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
CN112673105A (zh) 2018-07-09 2021-04-16 科德克希思公司 工程化脱氧核糖磷酸醛缩酶
JP7461658B2 (ja) 2018-07-09 2024-04-04 コデクシス, インコーポレイテッド 操作されたプリンヌクレオシドホスホリラーゼバリアント酵素
JP7491588B2 (ja) 2018-07-09 2024-05-28 コデクシス, インコーポレイテッド 操作されたパントテン酸キナーゼ改変体酵素
AU2019302422B2 (en) 2018-07-09 2022-08-04 Codexis, Inc. Engineered phosphopentomutase variant enzymes
EP3821000A4 (de) 2018-07-09 2022-07-20 Codexis, Inc. Manipulierte galaktose-oxidase-enzymvarianten
WO2020012266A1 (en) 2018-07-12 2020-01-16 Novartis Ag Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase
EP3820833A4 (de) 2018-07-12 2022-08-03 Codexis, Inc. Manipulierte phenylalanin-ammoniak-lyase-polypeptide
IL319918A (en) 2018-07-30 2025-05-01 Tate & Lyle Solutions Usa Llc Engineered glycosyltransferases and methods for glycosylation of steviol glycoside
WO2020025357A1 (en) 2018-08-02 2020-02-06 Novozymes A/S Preparation of combinatorial libraries of dna constructs using introns
US11473076B2 (en) 2018-08-31 2022-10-18 Novozymes A/S Animal feed additives and compositions comprising an S8 serine protease
CN113056476A (zh) 2018-10-03 2021-06-29 诺维信公司 具有α-甘露聚糖降解活性的多肽以及编码它们的多核苷酸
EP3864136A1 (de) 2018-10-09 2021-08-18 Novozymes A/S Modifizierte filamentöse pilzwirtszelle
JP7780186B2 (ja) 2018-10-29 2025-12-04 コデクシス, インコーポレイテッド 操作されたdnaポリメラーゼバリアント
EP3874051A1 (de) 2018-10-31 2021-09-08 Novozymes A/S Genombearbeitung durch geführte endonuklease und einzelsträngiges oligonukleotid
WO2020112911A1 (en) 2018-11-28 2020-06-04 Novozymes A/S Improved filamentous fungal host cells
US20220025423A1 (en) 2018-11-28 2022-01-27 Novozymes A/S Modified Filamentous Fungal Host Cells
EP3894576A1 (de) 2018-12-10 2021-10-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur herstellung von primären aminverbindungen
WO2020123845A1 (en) 2018-12-12 2020-06-18 Novozymes A/S Methods for increasing the productivity of a filamentous fungal cell in the production of a polypeptide
WO2020123463A1 (en) 2018-12-12 2020-06-18 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
AU2019397401A1 (en) 2018-12-14 2021-06-17 Codexis, Inc. Engineered tyrosine ammonia lyase
MY207075A (en) 2018-12-20 2025-01-28 Codexis Inc Human alpha-galactosidase variants
EP3898962A2 (de) 2018-12-21 2021-10-27 Novozymes A/S Polypeptide mit peptidoglycanabbauender aktivität und polynukleotide zur codierung davon
WO2020127198A1 (en) 2018-12-21 2020-06-25 Novozymes A/S Tandem protein expression
CA3126184A1 (en) 2019-01-11 2020-07-16 River Stone Biotech Aps Recombinant host cells with improved production of l-dopa, dopamine, (s)-norcoclaurine or derivatives thereof
CN113396218B (zh) 2019-01-15 2025-02-18 科德克希思公司 工程化转氨酶多肽
WO2020161354A1 (en) 2019-02-08 2020-08-13 Pili Recombinant host cells to produce anthraquinone derivatives
WO2020173817A1 (en) 2019-02-28 2020-09-03 Novozymes A/S Calcite binding proteins
CN113784990B (zh) 2019-03-08 2025-10-21 丹尼斯科美国公司 融合多肽
CA3128139A1 (en) 2019-03-18 2020-09-24 Novozymes A/S Polypeptides having pullulanase activity suitable for use in liquefaction
EP3737751B1 (de) 2019-03-21 2026-08-12 Fornia BioSolutions, Inc. Zusätzliche phytase-varianten und verfahren
EP3946720A1 (de) 2019-03-27 2022-02-09 Bunge Global Innovation, LLC. Silicaadsorbensbehandlung zur entfernung von chlorophyllderivaten aus triacylglycerol-basierten ölen
WO2020198731A2 (en) 2019-03-28 2020-10-01 Danisco Us Inc Engineered antibodies
CN113785039B (zh) 2019-04-03 2024-06-18 诺维信公司 具有β-葡聚糖酶活性的多肽、编码其的多核苷酸及其在清洁和洗涤剂组合物中的用途
US12247237B2 (en) 2019-04-10 2025-03-11 Novozymes A/S Polypeptide variants
MX2021012289A (es) 2019-04-12 2021-11-12 Novozymes As Variantes de glucosido hidrolasa estabilizadas.
EP3963057A4 (de) 2019-05-01 2023-06-14 Codexis, Inc. Manipulierte iminreduktasen und verfahren zur reduktiven aminierung von keton- und aminverbindungen
US12215359B2 (en) 2019-05-01 2025-02-04 Codexis, Inc. Engineered glucose dehydrogenases and methods for the reductive amination of ketone and amine compounds
WO2020229191A1 (en) 2019-05-15 2020-11-19 Novozymes A/S Temperature-sensitive rna-guided endonuclease
CN114207108A (zh) 2019-05-27 2022-03-18 奥克塔林生物制剂公司 产生糖基化大麻素的基因修饰的宿主细胞
US20220251528A1 (en) 2019-06-24 2022-08-11 Novozymes A/S Alpha-Amylase Variants
EP3986996A1 (de) 2019-06-24 2022-04-27 The Procter & Gamble Company Reinigungszusammensetzungen mit amylasevarianten
EP3990629A1 (de) 2019-06-25 2022-05-04 Novozymes A/S Gegenauswahl durch hemmung von bedingt essenziellen genen
EP3994255A1 (de) 2019-07-02 2022-05-11 Novozymes A/S Lipasevarianten und zusammensetzungen davon
KR20220025884A (ko) 2019-07-02 2022-03-03 코덱시스, 인코포레이티드 조작된 아세테이트 키나제 변이체 효소
AU2020300454A1 (en) 2019-07-02 2021-12-23 Codexis, Inc. Engineered sucrose phosphorylase variant enzymes
EP4004211A1 (de) 2019-07-25 2022-06-01 Novozymes A/S Fadenpilzexpressionssystem
US20220251581A1 (en) 2019-07-26 2022-08-11 Novozymes A/S Modified filamentous fungal host cell
BR112022003705A2 (pt) 2019-08-30 2022-05-24 Codexis Inc Lipase recombinante, composição, sequência de polinucleotídeo recombinante, vetor de expressão, composição farmacêutica para o tratamento de insuficiência pancreática, célula hospedeira, métodos para produzir uma lipase recombinante e para tratar e/ou prevenir os sintomas de insuficiência pancreática, e, uso
WO2021048172A2 (en) 2019-09-09 2021-03-18 River Stone Biotech Aps Delivery vehicle for in situ delivering of pharmaceutical agents
CN114760980B (zh) 2019-09-12 2024-10-18 科德克希思公司 针对10-乙酰基-3,7-二羟基吩噁嗪的过氧化物酶活性
EP4031661A1 (de) 2019-09-16 2022-07-27 Novozymes A/S Polypeptide mit beta-glucanase-aktivität und polynukleotide zur codierung davon
WO2021062435A1 (en) 2019-09-27 2021-04-01 The Procter & Gamble Company Consumer product compositions comprising fatty acid photodecarboxyalases
EP4038170A1 (de) 2019-10-03 2022-08-10 Novozymes A/S Polypeptide mit mindestens zwei kohlenhydratbindungsdomänen
WO2021086606A1 (en) 2019-10-28 2021-05-06 Danisco Us Inc Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases
US20210139879A1 (en) 2019-10-31 2021-05-13 The Procter & Gamble Company Consumer Product Compositions Comprising P450 Fatty Acid Decarboxylases
IL293038A (en) 2019-11-26 2022-07-01 Codexis Inc Biocatalysts and methods for hydroxylation of chemical compounds
CN114761551B (zh) 2019-12-19 2025-09-12 诺维信公司 木聚糖酶变体和编码其的多核苷酸
EP4077656A2 (de) 2019-12-20 2022-10-26 Novozymes A/S Polypeptide mit proteolytischer aktivität und verwendung davon
MX2022007399A (es) 2019-12-20 2022-09-19 Codexis Inc Variantes de alfa-glucosidasa ácida diseñadas.
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
WO2021152123A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
EP4097226A1 (de) 2020-01-31 2022-12-07 Novozymes A/S Mannanase-varianten und dafür codierende polynukleotide
EP4103711A4 (de) 2020-02-04 2024-02-28 Codexis, Inc. Gentechnisch veränderte leucindecarboxylasen
MX2022009515A (es) 2020-02-10 2022-09-02 Novozymes As Variantes de alfa-amilasa y polinucleotidos que las codifican.
WO2021163030A2 (en) 2020-02-10 2021-08-19 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2021163015A1 (en) 2020-02-10 2021-08-19 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
EP4110909A1 (de) 2020-02-26 2023-01-04 Novozymes A/S Polypeptidvarianten
CN115427560A (zh) 2020-03-12 2022-12-02 诺维信公司 使用无催化活性rna指导的内切核酸酶的crispr-aid
US20230203191A1 (en) 2020-03-30 2023-06-29 Danisco Us Inc Engineered antibodies
EP3892708A1 (de) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Reinigungszusammensetzungen mit dispersinvarianten
EP4133066A1 (de) 2020-04-08 2023-02-15 Novozymes A/S Kohlenhydratbindende modulvarianten
US11788071B2 (en) 2020-04-10 2023-10-17 Codexis, Inc. Engineered transaminase polypeptides
CA3179679A1 (en) 2020-04-10 2021-10-14 Codexis, Inc. Carboxyesterase polypeptides for kinetic resolution
CA3175523A1 (en) 2020-04-13 2021-10-21 Antti Virtanen Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
CN115516071A (zh) 2020-04-21 2022-12-23 诺维信公司 包含具有果聚糖降解活性的多肽的清洁组合物
WO2021236919A1 (en) 2020-05-20 2021-11-25 Wisconsin Alumni Research Foundation Cells and methods for producing methyl ketones
US20220043000A1 (en) 2020-08-04 2022-02-10 Abbott Laboratories Methods and kits for detecting sars-cov-2 protein in a sample
JP2023537982A (ja) 2020-08-13 2023-09-06 ノボザイムス アクティーゼルスカブ フィターゼ変異体及びそれをコードするポリヌクレオチド
JP7885201B2 (ja) 2020-08-25 2026-07-06 ノボザイムス アクティーゼルスカブ ファミリー44キシログルカナーゼの変異体
JP2023539634A (ja) 2020-08-28 2023-09-15 コデクシス, インコーポレイテッド 操作されたアミラーゼバリアント
EP4204548A1 (de) 2020-08-28 2023-07-05 Novozymes A/S Polyesterabbauende proteasevarianten
AU2021334371A1 (en) 2020-08-28 2023-03-09 Codexis, Inc. Engineered protease variants
CN116209754A (zh) 2020-09-28 2023-06-02 科德克希思公司 用于合成手性胺的工程化生物催化剂及方法
CN116710558A (zh) 2020-10-07 2023-09-05 科德克希思公司 工程化磷酸戊糖变位酶变体酶
US20220112446A1 (en) 2020-10-09 2022-04-14 The Procter & Gamble Company Cleaning composition comprising an alpha-dioxygenase
US20230407273A1 (en) 2020-10-13 2023-12-21 Novozymes A/S Glycosyltransferase variants for improved protein production
WO2022090361A2 (en) 2020-10-29 2022-05-05 Novozymes A/S Lipase variants and compositions comprising such lipase variants
AU2021370998A1 (en) 2020-11-02 2023-05-25 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US20240271175A1 (en) 2020-11-02 2024-08-15 Novozymes A/S Leader peptides and polynucleotides encoding the same
EP4026900A3 (de) 2020-12-17 2022-10-05 Fornia BioSolutions, Inc. Xylanasevarianten und verfahren
WO2022133289A2 (en) 2020-12-18 2022-06-23 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
EP4023757A1 (de) 2020-12-29 2022-07-06 The Protein Brewery B.V. Verfahren zur erzeugung von selektionsmarkerfreien transformanten von heterokaryotischen organismen
WO2022147147A1 (en) 2020-12-30 2022-07-07 Abbott Laboratories Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
WO2022175440A1 (en) 2021-02-18 2022-08-25 Novozymes A/S Inactive heme polypeptides
EP4305146A1 (de) 2021-03-12 2024-01-17 Novozymes A/S Polypeptidvarianten
EP4060036A1 (de) 2021-03-15 2022-09-21 Novozymes A/S Polypeptidvarianten
US20240060061A1 (en) 2021-03-15 2024-02-22 Novozymes A/S Dnase variants
MX2023005793A (es) 2021-03-15 2023-05-29 Procter & Gamble Composiciones de limpieza que contienen variantes de polipeptido.
EP4314261A1 (de) 2021-04-02 2024-02-07 Codexis, Inc. Manipulierte enzyme mit acetatkinasevarianten
US11913037B2 (en) 2021-04-02 2024-02-27 Codexis, Inc. Engineered adenylate kinase variant enzymes
IL305922A (en) 2021-04-02 2023-11-01 Codexis Inc Transgenic enzymes of variant guanylate kinase
WO2022212832A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered cyclic gmp-amp synthase (cgas) variant enzymes
AU2022270929A1 (en) 2021-05-07 2023-10-19 River Stone Biotech Aps Glycosylated opioids
AU2022279241A1 (en) 2021-05-21 2023-11-30 Syntis Bio, Inc. Engineered methionine gamma lyase variants
CN117355608A (zh) 2021-05-27 2024-01-05 诺维信公司 转录调节物和编码其的多核苷酸
EP4359518A1 (de) 2021-06-23 2024-05-01 Novozymes A/S Alpha-amylase-polypeptide
WO2023006699A1 (en) 2021-07-30 2023-02-02 Københavns Universitet Cells and method for producing isoprenoid molecules with canonical and non-canonical structures
US20230089159A1 (en) 2021-09-16 2023-03-23 The Procter & Gamble Company Cleaning composition comprising an engineered fatty acid alpha-dioxygenase
WO2023064938A1 (en) 2021-10-15 2023-04-20 Codexis, Inc. Engineered dna polymerase variants
WO2023069865A1 (en) 2021-10-15 2023-04-27 Codexis, Inc. Engineered terminal deoxynucleotidyl transferase variants
JP2024540358A (ja) 2021-11-01 2024-10-31 シンティス バイオ,インコーポレイティド 工学操作ロイシン脱炭酸酵素
WO2024015953A1 (en) 2022-07-15 2024-01-18 Danisco Us Inc. Methods for producing monoclonal antibodies
US20260168000A1 (en) 2022-11-08 2026-06-18 River Stone Biotech Aps Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression
US20260103688A1 (en) 2022-11-17 2026-04-16 Recombia Biosciences, Inc. Constructs and Methods for Biosynthesis of Gastrodin
IL322082A (en) 2023-01-12 2025-09-01 Novartis Ag Engineered ketoreductase polypeptides
EP4743572A1 (de) 2023-07-11 2026-05-20 DSM IP Assets B.V. Proteinarginindeiminase
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants
WO2026017657A1 (fr) 2024-07-15 2026-01-22 Pili Production d'acide p-aminobenzoïque par un microorganisme recombinant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE35176B1 (en) * 1970-05-14 1975-11-26 Ranks Hovis Mcdougall Ltd Improvements in the production of edible protein containing substances
US3937654A (en) * 1970-05-14 1976-02-10 Ranks Hovis Mcdougall Limited Production of edible protein substances
US4163692A (en) * 1977-04-25 1979-08-07 E. I. Du Pont De Nemours And Company Low phosphate growth of fungal mycelia
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
US5070020A (en) * 1988-05-09 1991-12-03 Eli Lilly And Company Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase
GB8904762D0 (en) * 1989-03-02 1989-04-12 Glaxo Group Ltd Biological process
GB9011347D0 (en) * 1990-05-21 1990-07-11 Ici Plc Production of a proteinaceous composition
CA2069147A1 (en) * 1991-05-22 1992-11-23 Kazuaki Kitano Dna and its use
FR2681076B1 (fr) * 1991-09-06 1994-11-18 Sanofi Elf Adn recombinant codant pour une proteine a activite endochitinase.
US5360901A (en) * 1992-03-04 1994-11-01 Genencor International, Inc. Gene sequence encoding Aspergillus niger catalase-R

Also Published As

Publication number Publication date
FI119437B (fi) 2008-11-14
FI965220A0 (fi) 1996-12-27
DE69534185D1 (de) 2005-06-09
DE69534185T2 (de) 2006-02-23
EP1559776A3 (de) 2006-01-11
CN1151762A (zh) 1997-06-11
CN101659926A (zh) 2010-03-03
JP3167729B2 (ja) 2001-05-21
JP2001169791A (ja) 2001-06-26
JP3511005B2 (ja) 2004-03-29
US5837847A (en) 1998-11-17
JPH10500024A (ja) 1998-01-06
AU2705895A (en) 1996-01-25
EP1559776A2 (de) 2005-08-03
FI965220L (fi) 1997-02-25
EP0777737B1 (de) 2005-05-04
WO1996000787A1 (en) 1996-01-11
EP0777737A1 (de) 1997-06-11

Similar Documents

Publication Publication Date Title
DE69534185D1 (de) Nicht-toxisches, nicht-toxigenes, nicht-pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
EP0722461A4 (de) Expression eines fusionspolypeptides, das ohne leadersequenz aus dem cytoplasma transportiert wird
DK374686A (da) Knoglemorphogenetiske midler, fremgangsmaade til fremstilling deraf og dna-sekvenser, nucleinsyresonder og rekombinante udtrykkelsesmedier til anvendelse derved
ATE80180T1 (de) Herstellung eines igg-bindenden proteins zum erleichtern der weiterverarbeitung mittels ''protein-engineering''.
EP0739980A3 (de) CD 19 Kodierende DNA
NZ190524A (en) Recombinant dna method for producing specific protein or polypeptide cleaving of bacterial gene for extracellular or periplasmic carrier protein
DE3669175D1 (de) Fusionsproteine, verfahren zu ihrer herstellung und ihre verwendung.
GEP20022619B (en) Novel Cell Systems Having Specific Interaction of Peptide Binding Pairs
KR960010863A (ko) 재조합 머사시딘 및 이의 제조방법
ATE79403T1 (de) Herstellung von thrombin-inhibitoren.
ATA192895A (de) Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
EP0760849A4 (de) Rekombinante, aud bpi und lbp basierende proteine, die für sie kodierenden nukleinsäuren, verfahren zu ihrer herstellung und ihre verwendung
FI875427A0 (fi) Menetelmä valmistaa hevosen -interferonia
GB9409985D0 (en) Vaccine against mycobacterial infections
KR880700855A (ko) 진핵생물 단백질을 발현시키는 개선된 방법
GB2171703B (en) Expression-secretion vector for gene expression and protein secretion, recombinant dna including the vector, and method of producing proteins by use of the re
DE69934017D1 (de) 2,6-beta-d-fruktanhydrolase enzym und verfahren zu dessen verwendung
DE3584029D1 (de) Expressionsvektoren, dns-fragmente, peptide, wirte und verfahren zur herstellung von peptiden.
WO2002050104A3 (en) Methods and cells for detecting modulators of rgs proteins
ATE43139T1 (de) Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.
EP0422217A4 (en) Human recombinant placental ribonuclease inhibitor and method of production
ATE439432T1 (de) Verfahren zur herstellung von säugetier-trypsinen
DK391185A (da) Rekombinant saccharomyces
ZA200007619B (en) New peptide fragments for protein purification.
FI963016A0 (fi) Heterologisten proteiinien ilmentäminen heikennetyissä bakteereissa käyttämällä htrA-promoottoreita

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties