FI965220L - Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ilmentämissysteemi ja siinä käytettävät promootterit ja terminaattorit - Google Patents

Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ilmentämissysteemi ja siinä käytettävät promootterit ja terminaattorit Download PDF

Info

Publication number
FI965220L
FI965220L FI965220A FI965220A FI965220L FI 965220 L FI965220 L FI 965220L FI 965220 A FI965220 A FI 965220A FI 965220 A FI965220 A FI 965220A FI 965220 L FI965220 L FI 965220L
Authority
FI
Finland
Prior art keywords
toxigenic
promoters
toxic
expression system
terminators used
Prior art date
Application number
FI965220A
Other languages
English (en)
Swedish (sv)
Other versions
FI119437B (fi
FI965220A0 (fi
Inventor
John C Royer
Donna L Moyer
Wendy T Yoder
Jeffrey R Shuster
Original Assignee
Novo Nordisk Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Biotech Inc filed Critical Novo Nordisk Biotech Inc
Publication of FI965220A0 publication Critical patent/FI965220A0/fi
Publication of FI965220L publication Critical patent/FI965220L/fi
Application granted granted Critical
Publication of FI119437B publication Critical patent/FI119437B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6427Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/929Fusarium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI965220A 1994-06-30 1996-12-27 Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ekspressiojärjestelmä ja siinä käytettäviä promoottereita ja terminaattoreita FI119437B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US26944994A 1994-06-30 1994-06-30
US26944994 1994-06-30
US40467895A 1995-03-15 1995-03-15
US40467895 1995-03-15
PCT/US1995/007743 WO1996000787A1 (en) 1994-06-30 1995-06-15 Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
US9507743 1995-06-15

Publications (3)

Publication Number Publication Date
FI965220A0 FI965220A0 (fi) 1996-12-27
FI965220L true FI965220L (fi) 1997-02-25
FI119437B FI119437B (fi) 2008-11-14

Family

ID=26953701

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965220A FI119437B (fi) 1994-06-30 1996-12-27 Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ekspressiojärjestelmä ja siinä käytettäviä promoottereita ja terminaattoreita

Country Status (9)

Country Link
US (1) US5837847A (fi)
EP (2) EP1559776A3 (fi)
JP (2) JP3167729B2 (fi)
CN (2) CN1151762A (fi)
AT (1) ATE294871T1 (fi)
AU (1) AU2705895A (fi)
DE (1) DE69534185T2 (fi)
FI (1) FI119437B (fi)
WO (1) WO1996000787A1 (fi)

Families Citing this family (705)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1154721C (zh) * 1996-07-24 2004-06-23 明治制果株式会社 葡聚糖内切酶以及含有该酶的纤维素酶制剂
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
JP4050329B2 (ja) 1997-05-16 2008-02-20 ノボザイムス,インコーポレイテッド プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸
JP2002515253A (ja) * 1998-05-20 2002-05-28 ノボザイムス バイオテック,インコーポレイティド トリコテセン−欠失糸状菌変異体細胞において異種ポリベプチドを生成するための方法
CN1230546C (zh) * 1998-10-06 2005-12-07 马克·阿龙·埃马尔法尔布 丝状真菌宿主领域的转化系统
WO2000024883A1 (en) 1998-10-26 2000-05-04 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
DE60037181T2 (de) * 1999-01-13 2008-10-09 Novozymes, Inc., Davis Verfahren zur herstellung von polypeptiden in cyclohexadepsipeptid-defizienten zellen
US6361973B1 (en) 1999-03-22 2002-03-26 Novozymes Biotech, Inc. Promoters for expressing genes in a fungal cell
CN100482801C (zh) * 1999-03-22 2009-04-29 诺沃奇梅兹有限公司 用于在真菌细胞中表达基因的启动子
AU6820000A (en) 1999-08-31 2001-03-26 Novozymes A/S Novel proteases and variants thereof
EP2133098A1 (en) 2000-01-10 2009-12-16 Maxygen Holdings Ltd G-CSF conjugates
PL206148B1 (pl) 2000-02-11 2010-07-30 Bayer HealthCare LLCBayer HealthCare LLC Koniugat polipeptydowy, polipeptyd, sekwencja nukleotydowa, wektor ekspresyjny, komórka gospodarz, sposób wytwarzania koniugatu polipeptydowego, środek farmaceutyczny i zastosowanie koniugatu polipeptydowego
ATE469223T1 (de) 2000-03-14 2010-06-15 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
EP2119773A1 (en) 2000-06-26 2009-11-18 Novozymes A/S Lipolytic enzymes from strains of fusarium and acremonium
AU2001279614B2 (en) 2000-08-21 2006-08-17 Novozymes A/S Subtilase enzymes
CN1452656B (zh) 2000-09-05 2011-06-15 诺维信公司 脂肪氧合酶
WO2002074806A2 (en) 2001-02-27 2002-09-26 Maxygen Aps New interferon beta-like molecules
CA2444735C (en) 2001-04-20 2012-10-23 Novozymes A/S Lipoxygenase
DK2298868T3 (en) 2001-06-26 2015-04-20 Novozymes As Polypeptides with cellobiohydrolase I activity and the same coding polynucleotides
DE10207702C1 (de) * 2002-02-22 2003-08-28 Albrecht Gmbh Einstellbare Gelenkorthese
US8148155B2 (en) 2002-04-22 2012-04-03 Novozymes, Inc. Methods for increasing homologous recombination of a nucleic acid sequence
AU2003231228A1 (en) 2002-04-22 2003-11-03 Novozymes Biotech, Inc. Methods for preparing variants of a dna sequence in filamentous fungi
CN1694953B (zh) 2002-08-30 2010-05-12 诺维信股份有限公司 制备哺乳动物胰蛋白酶的方法
ATE452184T1 (de) * 2002-09-24 2010-01-15 Novozymes Inc Mikrobielle trypsinvarianten mit chymotrypsinaktivität und diese codierende nukleinsäuren
ATE494368T1 (de) 2002-10-01 2011-01-15 Novozymes As Polypeptide der gh-61-familie
JP4490284B2 (ja) 2002-11-18 2010-06-23 ノボザイムス,インコーポレイティド 菌類細胞において遺伝子を発現するためのプロモーター変異体
EP2128247A1 (en) 2002-12-20 2009-12-02 Novozymes A/S Polypeptides having cellobiohydrolase II activity and polynucleotides encoding same
EP1613761B1 (en) 2003-03-31 2009-09-02 Novozymes Inc. Methods for producing biological substances in enzyme-deficient mutants of aspergillus niger
BRPI0409599B1 (pt) 2003-04-28 2014-09-16 Novozymes As Sequência de ácido nucléico, construto de ácido nucléico, vetor de expressão recombinante, micro-organismo recombinante, composição de massa, métodos de produzir uma fosfolipase, de preparar uma massa ou um produto assado feito da massa, processos para reduzir o conteúdo de fósforo em um óleo vegetal e para produzir queijo
DK1622921T3 (da) 2003-05-02 2010-09-13 Novozymes Inc Varianter af beta-glucosidaser
ES2346654T3 (es) 2003-06-19 2010-10-19 Novozymes A/S Proteasas.
US20060236414A1 (en) 2003-06-19 2006-10-19 Novozymes A/S Proteases and methods for producing them
AU2004252572B2 (en) 2003-06-25 2011-09-08 Novozymes A/S Polypeptides having alpha-amylase activity and polypeptides encoding same
DK2377931T3 (da) 2003-08-25 2013-07-08 Novozymes Inc Varianter af glycosidhydrolase
JP4880469B2 (ja) 2003-10-23 2012-02-22 ノボザイムス アクティーゼルスカブ 洗剤中で改良された安定性を有するプロテアーゼ
ES2340390T3 (es) 2003-10-28 2010-06-02 Novozymes North America, Inc. Enzimas hibridas.
DK1682656T3 (da) 2003-10-28 2013-11-18 Novozymes Inc Polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem
WO2005066339A2 (en) 2004-01-06 2005-07-21 Novozymes A/S Polypeptides of alicyclobacillus sp.
EP2305703B1 (en) 2004-01-30 2014-03-12 Novozymes Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
DK2322630T3 (en) 2004-02-12 2017-02-13 Novozymes Inc Polypeptides with xylanase activity and polynucleotides encoding them
AU2005215852B2 (en) 2004-02-25 2010-04-22 Novozymes A/S Fungal cell wall degrading enzyme
DK1735454T3 (en) 2004-03-25 2017-08-28 Novozymes Inc PROCEDURES FOR DEVELOPMENT OR CONVERSION OF PLANT CELL CELL POLICY ACCHARIDES
CN102286483B (zh) 2004-04-16 2014-06-04 中化帝斯曼制药有限公司荷兰公司 用于在真菌细胞中表达基因的真菌启动子
US7148404B2 (en) 2004-05-04 2006-12-12 Novozymes A/S Antimicrobial polypeptides
CA2565888C (en) 2004-05-27 2014-10-14 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a dna library
CA2567485C (en) 2004-05-27 2015-01-06 Genencor International, Inc. Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
WO2005121333A1 (en) 2004-06-14 2005-12-22 Novozymes A/S Signal peptide for producing a polypeptide
EP1766002B1 (en) 2004-06-21 2015-11-18 Novozymes A/S Stably maintained multiple copies of at least two orf in the same orientation
EP1766001B1 (en) 2004-06-21 2012-01-11 Novozymes A/S Nocardiopsis proteases
CN104195123A (zh) 2004-06-29 2014-12-10 诺维信股份有限公司 具有α-葡糖苷酶活性的多肽及编码其的多核苷酸
EP2295555A3 (en) 2004-09-30 2011-08-10 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encodig same
CN103224918B (zh) 2004-10-04 2015-08-26 诺维信公司 具有肌醇六磷酸酶活性的多肽和编码它的多核苷酸
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
WO2006053565A2 (en) 2004-11-19 2006-05-26 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
DK1831384T3 (en) 2004-12-22 2015-11-23 Novozymes As Polypeptides with glucoamylase activity and polynucleotides encoding them.
JP2008527985A (ja) 2005-01-24 2008-07-31 ディーエスエム アイピー アセッツ ビー.ブイ. 糸状菌細胞において目的の化合物を産生させるための方法
BRPI0608518A2 (pt) 2005-03-16 2012-12-11 Novozymes As célula hospedeira fúngica filamentosa recombinante, método para a produção recombinante de uma defensina em uma célula hospedeira fúngica filamentosa, e, uso de uma construção de ácido nucleico
ATE473999T1 (de) 2005-03-22 2010-07-15 Novozymes As Polypeptide und nukleinsäuren, die diese codieren
AR053066A1 (es) 2005-04-26 2007-04-18 Novozymes As Arabinofuranosidasas
US7824884B2 (en) 2005-04-27 2010-11-02 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2007019859A2 (en) 2005-08-16 2007-02-22 Novozymes A/S Polypeptides of strain bacillus sp. p203
ES2343586T3 (es) 2005-08-26 2010-08-04 Novozymes Adenium Biotech A/S Polipeptidos con actividad antimicrobiana y polinucleotidos que codifican los mismos.
EP2385110A3 (en) 2005-09-30 2011-11-16 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
CN101292024B (zh) 2005-10-17 2012-04-18 诺维信公司 用于表达抗体的真菌突变体的用途
CA2630455A1 (en) 2005-11-29 2007-06-07 Dsm Ip Assets B.V. Dna binding site of a transcriptional activator useful in gene expression
EP2336309A3 (en) 2006-03-20 2011-08-10 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2007115201A2 (en) 2006-03-30 2007-10-11 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
PL2365064T3 (pl) 2006-04-04 2015-05-29 Novozymes As Warianty fitazy
US20080026376A1 (en) 2006-07-11 2008-01-31 Huaming Wang KEX2 cleavage regions of recombinant fusion proteins
US8198046B2 (en) 2006-07-11 2012-06-12 Danisco Us Inc. KEX2 cleavage regions of recombinant fusion proteins
CN103451164A (zh) 2006-07-14 2013-12-18 诺维信股份有限公司 用于产生具有生物学活性的分泌型多肽的方法
DK2044203T3 (da) 2006-07-14 2014-01-20 Novozymes Inc Fremgangsmåder til forøgelse af ekspression af gener i en svampecelle
EP2046819B1 (en) 2006-07-21 2015-03-18 Novozymes, Inc. Methods of increasing secretion of polypeptides having biological activity
WO2008039370A1 (en) 2006-09-22 2008-04-03 Danisco Us, Inc., Genencor Division Acetolactate synthase (als) selectable marker from trichoderma reesei
BRPI0719181A2 (pt) 2006-10-10 2014-08-05 Danisco Us Inc Genencor Div Variantes de glucoamilase com propriedades alteradas
WO2008065200A1 (en) 2006-11-30 2008-06-05 Novozymes A/S Dnase expression in recombinant host cells
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
EP2505651A3 (en) 2006-12-10 2013-01-09 Dyadic International, Inc. Isolated fungus with reduced protease activity
MX2009005734A (es) 2006-12-18 2009-06-10 Danisco Us Inc Genencor Div Mediadores de lacasa y metodos de uso.
US20080220498A1 (en) 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
AU2008214663B2 (en) 2007-02-15 2013-10-03 Dsm Ip Assets B.V. A recombinant host cell for the production of a compound of interest
PL2129781T3 (pl) 2007-03-26 2014-07-31 Novozymes As Fitaza z Hafnia
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
EP2147107B1 (en) 2007-05-09 2011-07-20 Novozymes A/S Expression cloning method suitable for selecting library clones producing a polypeptide of interest
US8093016B2 (en) 2007-05-21 2012-01-10 Danisco Us Inc. Use of an aspartic protease (NS24) signal sequence for heterologous protein expression
EP2195443B1 (en) 2007-08-24 2015-01-07 Codexis, Inc. Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
WO2009033071A2 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
WO2009035500A1 (en) 2007-09-12 2009-03-19 Danisco Us Inc., Genencor Division Trichoderma promoter
EP2193195B1 (en) 2007-09-18 2014-12-17 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
US8592194B2 (en) 2007-10-09 2013-11-26 Danisco Us Inc. Glucoamylase variants with altered properties
ES2518916T3 (es) 2007-10-09 2014-11-05 Danisco Us Inc. Variantes de glucoamilasa con propiedades modificadas
CA2705941C (en) 2007-11-20 2018-05-22 Danisco Us Inc. Glucoamylase variants with altered properties
BRPI0820552A2 (pt) 2007-11-27 2014-10-14 Novozymes As Polipetídeo isolado, polinucleotídeo isolado, construção de ácido nucléico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir o polipeptídeo, para produzir uma proteína, e para degradar ou converter um material de biomassa, planta, parte vegetal ou célula vegetal transgêncica, método, composição, e. uso do polipeptídio.
ES2490608T3 (es) 2007-12-06 2014-09-04 Novozymes A/S Polipéptidos con actividad de esterasa de acetilxilano y polinucleótidos que codifican los mismos
JP2011507525A (ja) 2007-12-19 2011-03-10 ノボザイムス アクティーゼルスカブ セルロース分解増強活性を有するポリペプチドとこれをコードするポリヌクレオチド
DK3118309T3 (da) 2008-04-18 2020-12-14 Danisco Us Inc Buttiauxella sp. phytasevarianter
CN102057042B (zh) 2008-06-06 2014-07-16 诺维信公司 家族44木葡聚糖酶变体
MX2010014500A (es) 2008-06-24 2011-05-30 Codexis Inc Procedimientos biocataliticos para la preparacion de compuestos de prolina biciclica fusionada sustancialmente estereomericamente puros.
ES2560459T3 (es) 2008-08-27 2016-02-19 Codexis, Inc. Polipéptidos cetorreductasa para la producción de una 3-aril-3-hidroxipropanamina a partir de una 3-aril-3-cetopropanamina
EP2650364B1 (en) 2008-09-26 2015-05-20 Novozymes A/S Hafnia phytase variants
WO2010059413A2 (en) 2008-11-20 2010-05-27 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
CN102300986A (zh) 2008-12-04 2011-12-28 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
WO2010068650A1 (en) 2008-12-12 2010-06-17 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encoding same
WO2010068800A1 (en) 2008-12-12 2010-06-17 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
WO2010074972A1 (en) 2008-12-15 2010-07-01 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
EP2379716A1 (en) 2008-12-16 2011-10-26 Novozymes Inc. Polypeptides having alpha-mannosidase activity and polynucleotides encoding same
WO2010074955A1 (en) 2008-12-16 2010-07-01 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
DK2379712T3 (en) 2008-12-19 2017-05-08 Novozymes Inc Methods for Increasing Hydrolysis of Cellulosic Material in the Presence of Cellobiose Dehydrogenase
WO2010080407A2 (en) 2008-12-19 2010-07-15 Novozymes, Inc. Methods for increasing hydrolysis of cellulosic material
US8338121B2 (en) 2008-12-19 2012-12-25 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
CN102325893A (zh) 2008-12-19 2012-01-18 诺维信股份有限公司 在过氧化物酶存在下增加纤维素材料酶法水解的方法
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
DK3037528T3 (en) 2008-12-23 2018-12-10 Dupont Nutrition Biosci Aps POLYPEPTIDES
DK2385983T3 (en) 2009-01-08 2018-02-12 Codexis Inc Transaminase POLYPEPTIDES
US8637292B2 (en) 2009-01-21 2014-01-28 Novozymes A/S Polypeptides having feruloyl esterase activity and nucleic acids encoding the same
WO2010088387A1 (en) 2009-01-28 2010-08-05 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010088463A2 (en) 2009-01-30 2010-08-05 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2408314A1 (en) 2009-03-17 2012-01-25 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
WO2010108918A1 (en) 2009-03-24 2010-09-30 Novozymes A/S Polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
CN102428170B (zh) 2009-03-31 2015-03-18 科德克希思公司 改良的内切葡聚糖酶
CN102414323B (zh) 2009-04-22 2015-07-08 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的重组多肽的方法
EP2248893A1 (en) 2009-05-06 2010-11-10 Novozymes A/S DFPase Enzymes from Octopus Vulgaris
US20100298612A1 (en) 2009-05-22 2010-11-25 Codexis, Inc. Engineered biosynthesis of fatty alcohols
BRPI1011597B1 (pt) 2009-05-29 2019-08-20 Novozymes, Inc. Métodos para degradar um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico, e, composição de enzima
CN102482652B (zh) 2009-06-02 2014-12-17 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
HUE055413T2 (hu) 2009-06-22 2021-11-29 Codexis Inc Ketoreduktáz-közvetített sztereoszelektív útvonal alfa-klóralkoholokhoz
EP2446029B1 (en) 2009-06-26 2016-08-10 Novozymes North America, Inc. Heat-stable carbonic anhydrases and their use
CA2766585C (en) 2009-06-30 2016-03-01 Codexis, Inc. Production of fatty alcohols with fatty alcohol forming acyl-coa reductases (far)
CN102597243B (zh) 2009-07-07 2015-05-20 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
AU2010275672A1 (en) 2009-07-22 2012-02-02 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
US20120100250A1 (en) 2009-07-24 2012-04-26 Novozymes A/S Carbohydrate Oxidases
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
EP2462156A1 (en) 2009-08-07 2012-06-13 Novozymes A/S Method of producing a sweet protein
WO2011022465A1 (en) 2009-08-19 2011-02-24 Danisco Us Inc. Combinatorial variants of glucoamylase with improved specific activity and/or thermostability
JP5827227B2 (ja) 2009-08-19 2015-12-02 デュポン ニュートリション バイオサイエンシーズ エーピーエスDuPont Nutrition Biosciences ApS グルコアミラーゼの変異体
WO2011020910A1 (en) 2009-08-21 2011-02-24 Novozymes A/S Polypeptides having isoamylase activity and polynucleotides encoding same
JP5833553B2 (ja) 2009-09-01 2015-12-16 ノボザイムス,インコーポレイティド 糸状菌におけるリンゴ酸生成の改良方法
WO2011035027A2 (en) 2009-09-17 2011-03-24 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011035029A1 (en) 2009-09-18 2011-03-24 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
AU2010299800B2 (en) 2009-09-25 2014-08-07 Novozymes A/S Use of protease variants
MX339581B (es) 2009-09-25 2016-06-01 Novozymes As Variantes de subtilasa.
US8211665B2 (en) 2009-09-29 2012-07-03 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
US8148103B2 (en) 2009-09-29 2012-04-03 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
BR112012007390A2 (pt) 2009-09-30 2015-09-15 Novozymes As polipeptídeo isolado tendo atividade intensificadora celulolítica, polinucleotídeo isolado, métodos para produzir o polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degragar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada com um polinucleotídeo, molécula inibidora de filamento duplo, e, composição detergente
ES2551141T3 (es) 2009-09-30 2015-11-16 Novozymes Inc. Polipéptidos derivados de Thermoascus crustaceus con actividad de aumento celulolítico y polinucleótidos que codifican los mismos
WO2011041594A1 (en) 2009-09-30 2011-04-07 Codexis, Inc. Recombinant c1 b-glucosidase for production of sugars from cellulosic biomass
US8541651B2 (en) 2009-10-23 2013-09-24 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
CN102666847B (zh) 2009-10-29 2015-12-09 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
MX2012005152A (es) 2009-11-06 2012-06-12 Novozymes Inc Composiciones para sacrificacion de material celulosico.
DK2496692T3 (en) 2009-11-06 2016-06-27 Novozymes Inc POLYPEPTIDES WITH xylanase AND POLYNUCLEOTIDES ENCODING THEM
WO2011057086A1 (en) 2009-11-06 2011-05-12 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112012012192A2 (pt) 2009-11-25 2017-07-04 Codexis Inc b-glicosidades variantes recombinantes thermoascus aurantiacus para produção de açúcares fermentáveis a partir da biomassa celulósica
US8143050B2 (en) 2009-11-25 2012-03-27 Codexis, Inc. Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass
MX2012006095A (es) 2009-11-30 2012-07-03 Novozymes North America Inc Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos.
WO2011066576A1 (en) 2009-11-30 2011-06-03 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
MX2012006176A (es) 2009-12-01 2012-06-25 Novozymes North America Inc Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que codifican los mismos.
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
CN106929494B (zh) 2009-12-09 2021-05-14 诺维信公司 产生gh8木聚糖酶变体的方法
CN102753680B (zh) 2009-12-11 2015-05-13 诺维信公司 蛋白酶变体
BR122018077148B1 (pt) 2009-12-18 2020-11-03 Novozymes, Inc mutante de uma cepa de trichoderma reesei parental isolada, e, métodos para produzir um polipeptídeo de inetresse e para obter um mutante de uma cepa de trichoderma reesei parental
WO2011080267A2 (en) 2009-12-29 2011-07-07 Novozymes A/S Polypetides having detergency enhancing effect
US20120270267A1 (en) 2010-01-04 2012-10-25 Novozymes A/S Alpha-Amylases
US8617856B2 (en) 2010-01-07 2013-12-31 Wisconsin Alumni Research Foundation Fatty acid-producing hosts
CN102762727B (zh) 2010-02-11 2016-07-20 帝斯曼知识产权资产管理有限公司 能产生用于降解木质纤维素材料的酶的宿主细胞
CN102858968B (zh) 2010-02-25 2015-07-01 诺维信公司 溶菌酶的变体及编码该变体的多核苷酸
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
CN102884182A (zh) 2010-03-03 2013-01-16 诺维信股份有限公司 木聚糖酶变体及编码其的多核苷酸
US20110229921A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
US9173421B2 (en) 2010-03-26 2015-11-03 Novozymes A/S Thermostable phytase variants
MX2012011153A (es) 2010-03-31 2012-11-29 Novozymes Inc Variantes de celobiohidrolasa y polinucleotidos que codifican las mismas.
MX338068B (es) 2010-04-14 2016-04-01 Novozymes As Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que codifican los mismos.
WO2011150313A1 (en) 2010-05-28 2011-12-01 Codexis, Inc. Pentose fermentation by a recombinant microorganism
DK2576606T3 (en) 2010-06-04 2015-02-23 Novozymes Inc Preparation of C4 dicarboxylic acid in filamentous fungi
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
CN102947458B (zh) 2010-06-21 2016-05-04 诺维信股份有限公司 用于丝状真菌中c4-二羧酸的改善的产生的方法
CA2803343C (en) 2010-06-21 2018-08-07 Novozymes, Inc. Aspergillus aculeatus derived polypeptides having c4-dicarboxylic acid transporter activity and polynucleotides encoding same
WO2011161207A1 (en) 2010-06-25 2011-12-29 Novozymes A/S Polynucleotides having promoter activity
EP2585591B1 (en) 2010-06-25 2014-12-24 Novozymes A/S Polynucleotides having leader sequence function
WO2011161208A1 (en) 2010-06-25 2011-12-29 Novozymes A/S Polynucleotides having promoter activity
WO2011163558A1 (en) 2010-06-25 2011-12-29 Abbott Laboratories Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies
BR112012033361A2 (pt) 2010-06-28 2020-10-20 Codexis, Inc. acul-redutases formadoras de álcoois graxos (fars) e seus modos de uso.
CN103108951A (zh) 2010-06-30 2013-05-15 诺维信公司 具有β-葡糖苷酶活性的多肽和编码该多肽的多核苷酸
CN103459600B (zh) 2010-07-01 2016-10-19 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的化合物的方法
EP2598629B1 (en) 2010-07-30 2020-04-08 Cleanvantage LLC Aspergillus containing beta-glucosidase, beta-glucosidases and nucleic acids encoding the same
BR112013002979A2 (pt) 2010-08-12 2016-06-07 Novozymes Inc composição, e, método para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico.
CN103298921A (zh) 2010-08-17 2013-09-11 诺维信公司 酿造方法
US9493802B2 (en) 2010-08-20 2016-11-15 Codexis, Inc. Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose
WO2012025577A1 (en) 2010-08-24 2012-03-01 Novozymes A/S Heat-stable persephonella carbonic anhydrases and their use
US20130212746A1 (en) 2010-08-30 2013-08-15 Novoyzmes A/S Polypeptides Having Hemicellulolytic Activity And Polynucleotides Encoding Same
WO2012030811A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US9267126B2 (en) 2010-08-30 2016-02-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
EP2611901B1 (en) 2010-08-30 2016-05-11 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
US9303074B2 (en) 2010-08-30 2016-04-05 Novoyzmes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2616483A1 (en) 2010-09-16 2013-07-24 Novozymes A/S Lysozymes
BR112013007693B1 (pt) 2010-09-30 2021-12-07 Novozymes, Inc Variante, polinucleotídeo isolado, célula hospedeira microbiana recombinante, métodos para produzir uma variante, para produzir uma variante tendo atividade intensificadora celulolítica, para degradar um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, e, composição enzimática, formulação do caldo completo ou composição de cultura de células
CN107345226A (zh) 2010-09-30 2017-11-14 诺维信股份有限公司 具有纤维素分解增强活性的多肽变体及其编码多核苷酸
EP3023492B1 (en) 2010-10-01 2018-01-24 Novozymes, Inc. Beta-glucosidase variants and polynucleotides encoding same
CA2809916A1 (en) 2010-10-01 2012-04-05 Novozymes A/S Polypeptides having endopeptidase activity and polynucleotides encoding same
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
CN103314100A (zh) 2010-10-29 2013-09-18 诺维信公司 重组正丙醇和异丙醇产生
CN103282376A (zh) 2010-10-29 2013-09-04 诺维信公司 具有琥珀酰CoA:乙酰乙酸转移酶活性的多肽及其编码多核苷酸
DK2635689T3 (en) 2010-11-02 2015-07-06 Novozymes Inc METHODS OF PREPARATION OF cellulosic material WITH A GH61-POLYPEPTIDE
WO2012059053A1 (en) 2010-11-04 2012-05-10 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US9732332B2 (en) 2010-11-08 2017-08-15 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
ES2649555T3 (es) 2010-11-08 2018-01-12 Novozymes A/S Polipéptidos con actividad glucoamilasa y polinucleótidos que los codifican
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
BR122020023911B1 (pt) 2010-11-12 2022-02-15 Novozymes A/S Construto de ácido nucleico, célula microbiana hospedeira recombinante, e, método de produção do polipeptídeo
WO2012062220A1 (en) 2010-11-12 2012-05-18 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
DK2640833T3 (en) 2010-11-18 2016-11-28 Novozymes Inc Chimeric polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM
CN105420267A (zh) 2010-11-30 2016-03-23 诺维信股份有限公司 用于在真菌细胞中表达基因的启动子
US8927235B2 (en) 2010-12-06 2015-01-06 Novozymes A/S Methods of hydrolyzing oligomers in hemicellulosic liquor
CA2820248C (en) 2010-12-07 2019-10-29 Vnomics Corp. System and method for measuring and reducing vehicle fuel waste
US9284588B2 (en) 2010-12-16 2016-03-15 Novozymes, Inc. Promoters for expressing genes in a fungal cell
EP2665812B1 (en) 2011-01-20 2016-09-14 Novozymes A/S Expression of plant peroxidases in filamentous fungi
MX337919B (es) 2011-01-26 2016-03-28 Novozymes As Polipeptidos que tienen actividad de celobiohidrolasa y polinucleotidos que codifican los mismos.
CN105838698B (zh) 2011-01-26 2019-10-11 诺维信公司 具有纤维二糖水解酶活性的多肽及编码该多肽的多核苷酸
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
MX337942B (es) 2011-01-26 2016-03-29 Novozymes As Polipeptidos que tienen actividad de endoglucanasa y polinucleotidos que codifican los mismos.
CA2834023A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
CN103459605B (zh) 2011-01-31 2016-08-24 诺维信北美公司 用于酶法精制经预处理的纤维素材料以供糖化的工艺
EP2678427A2 (en) 2011-02-23 2014-01-01 DuPont Nutrition Biosciences ApS Method for producing recombinant enzymes capable of hydrolysing chlorophyll or a chlorophyll derivative
WO2012113340A1 (en) 2011-02-23 2012-08-30 Novozymes Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
DK3339442T3 (da) 2011-03-09 2022-06-20 Novozymes Inc Fremgangsmåder til forøgelse af den cellulolyseforbedrende aktivitet af et polypeptid
US9409958B2 (en) 2011-03-10 2016-08-09 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2683732B1 (en) 2011-03-11 2016-08-24 DSM IP Assets B.V. Vector-host system
EP2689011B1 (en) 2011-03-25 2017-10-25 Novozymes A/S Method for degrading or converting cellulosic material
WO2012135110A1 (en) 2011-03-30 2012-10-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
WO2012135719A1 (en) 2011-03-31 2012-10-04 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
DK2702153T3 (en) 2011-04-28 2019-03-18 Novozymes Inc Polypeptides with endoglucanase activity and polynucleotides encoding them
BR112013027463A2 (pt) 2011-04-29 2017-09-26 Novozymes Inc métodos para degradar ou converter, e para fermentar um material celulóliso, para produzir um produto de fermentação, e para limpar ou lavar uma superfície dura ou roupa suja, e, composição de detergente
WO2012159009A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
WO2012159007A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
EP2723858B1 (en) 2011-06-24 2017-04-12 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
HUE042817T2 (hu) 2011-06-28 2019-07-29 Codexis Inc Fehérjevariánsok elõállítása régiókeveréssel
JP6204352B2 (ja) 2011-06-30 2017-09-27 ノボザイムス アクティーゼルスカブ α−アミラーゼ変異体
WO2013003219A1 (en) 2011-06-30 2013-01-03 Codexis, Inc. Pentose fermentation by a recombinant microorganism
AU2012277729B2 (en) 2011-06-30 2016-12-08 Novozymes A/S Method for screening alpha-amylases
CA2840962C (en) 2011-07-06 2021-04-13 Novozymes A/S Alpha amylase variants and polynucleotides encoding same
WO2013010783A1 (en) 2011-07-15 2013-01-24 Novozymes A/S Lipase variants and polynucleotides encoding same
US20140147895A1 (en) 2011-07-22 2014-05-29 Novozymes A/S Processes for Pretreating Cellulosic Material and Improving Hydrolysis Thereof
BR112014002401B1 (pt) 2011-08-04 2021-08-03 Novozymes A/S Célula hospedeira transgênica de fungo filamentoso, métodos para produzir um polipeptídeo e uma proteína, e, construto de ácido nucleico ou um vetor de expressão
WO2013019780A2 (en) 2011-08-04 2013-02-07 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
CN103732740B (zh) 2011-08-10 2018-07-31 诺维信公司 具有过氧化酶活性的多肽及编码该多肽的多核苷酸
WO2013021060A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021061A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
JP2014531895A (ja) 2011-08-15 2014-12-04 ノボザイムス アクティーゼルスカブ セルラーゼ活性を有するポリペプチドおよびそれをコードするポリヌクレオチド
AU2012298598B2 (en) 2011-08-19 2017-02-23 Novozymes A/S Polypeptides having protease activity
ES2579706T3 (es) 2011-08-19 2016-08-16 Novozymes, Inc. Microorganismos recombinantes para la producción de ácidos C4-dicarboxílicos
BR112014004171A2 (pt) 2011-08-22 2018-11-06 Codexis Inc variantes da proteína glicósideo hidrolase gh61 e cofatores que aumentam a atividade de gh61
DK2748314T3 (en) 2011-08-24 2017-03-20 Novozymes Inc CELLULOLYTIC ENZYME COMPOSITIONS FROM ASPERGILLUS FUMIGATUS AND APPLICATIONS THEREOF
BR112014004186B1 (pt) 2011-08-24 2020-12-15 Novozymes, Inc. Composição enzimática, célula hospedeira de fungo filamentoso recombinante, método para produzir uma composição enzimática, processos para degradar um material celulósico, para sintetizar um produto de fermentação, e, para fermentar um material celulósico
BR112014004188A2 (pt) 2011-08-24 2017-03-21 Novozymes Inc método para obter transformantes positivos de uma célula hospedeira fúngica filamentosa, célula hospedeira fúngica filamentosa, método para produzir múltiplos polipeptídeos recombinantes, e, construto em tandem
US9493790B2 (en) 2011-08-24 2016-11-15 Novozymes, Inc. Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
EP2748188A4 (en) 2011-08-26 2015-03-18 Novozymes As POLYPEPTIDES WITH GLUCCOAMYLASE ACTIVITY AND THESE CODING POLYNUCLEOTIDES
CN103930543B (zh) 2011-09-06 2020-11-27 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
US9109209B2 (en) 2011-09-08 2015-08-18 Codexis, Inc. Biocatalysts and methods for the synthesis of substituted lactams
US9994834B2 (en) 2011-09-09 2018-06-12 Novozymes A/S Polynucleotides encoding polypeptides having alpha-amylase activity and methods of making the same
EP2756091A1 (en) 2011-09-13 2014-07-23 Novozymes North America, Inc. Methods of hydrolyzing and fermenting cellulosic material
US20140308705A1 (en) 2011-09-20 2014-10-16 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
EP2751266B1 (en) 2011-09-22 2017-03-29 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
CN103930438A (zh) 2011-09-30 2014-07-16 诺维信股份有限公司 具有β-葡糖苷酶活性的嵌合多肽和对其进行编码的多核苷酸
WO2013049073A1 (en) 2011-09-30 2013-04-04 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
US20150031091A1 (en) 2011-09-30 2015-01-29 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
JP2014530020A (ja) 2011-10-04 2014-11-17 フロリダ大学リサーチファウンデーション インコーポレイティッド D−乳酸脱水素酵素活性を有するグリセロール脱水素酵素の変異体およびその使用
WO2013053801A1 (en) 2011-10-11 2013-04-18 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP2748316B1 (en) 2011-10-17 2018-12-19 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CA2852601C (en) 2011-10-17 2023-05-23 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2013067026A1 (en) 2011-10-31 2013-05-10 Bp Corporation North America Inc. Use of plant promoters in filamentous fungi
US10308921B2 (en) 2011-10-31 2019-06-04 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2013067028A1 (en) 2011-10-31 2013-05-10 Bp Corporation North America Inc. Use of mammalian promoters in filamentous fungi
EP2780449B1 (en) 2011-11-18 2018-04-11 Novozymes, Inc. Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
EP2802651B1 (en) 2011-11-21 2017-03-08 Novozymes, Inc. Gh61 polypeptide variants and polynucleotides encoding same
US9695433B2 (en) 2011-11-22 2017-07-04 Novozymes Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
EP2782592B1 (en) 2011-11-25 2017-03-15 Novozymes A/S Polypeptides having lysozyme activity and polynucleotides encoding same
DK2785732T3 (en) 2011-12-01 2017-06-19 Novozymes Inc POLYPEPTIDES WITH BETA-XYLOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
WO2013079531A2 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013079533A1 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2788491B1 (en) 2011-12-09 2019-01-23 Danisco US Inc. Ribosomal promotors from b. subtilis for protein production in microorganisms
DK2791330T3 (da) 2011-12-16 2017-11-06 Novozymes Inc Polypeptider med laccaseaktivitet og polynukleotider, som koder for dem
WO2013091547A1 (en) 2011-12-19 2013-06-27 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
EP2794871A4 (en) 2011-12-20 2015-12-30 Codexis Inc VARIANTS OF ENDOGLUCANASE-1B (EG1B)
EP2794869B1 (en) 2011-12-20 2017-10-04 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
ES2667318T3 (es) 2011-12-28 2018-05-10 Novozymes A/S Polipéptidos con actividad de proteasa
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
US9801398B2 (en) 2012-01-26 2017-10-31 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
EP2623586B1 (en) 2012-02-03 2017-08-16 The Procter & Gamble Company Compositions and methods for surface treatment with lipases
EP3696265B1 (en) 2012-02-03 2025-03-19 Novozymes A/S Lipase variants and polynucleotides encoding same
WO2013123871A1 (en) 2012-02-20 2013-08-29 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2013142770A1 (en) 2012-03-23 2013-09-26 Codexis, Inc. Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
CN107988181A (zh) 2012-04-02 2018-05-04 诺维信公司 脂肪酶变体以及编码其的多核苷酸
CN104245929A (zh) 2012-04-23 2014-12-24 诺维信公司 具有α-葡糖醛酸糖苷酶活性的多肽以及编码其的多核苷酸
US9394556B2 (en) 2012-04-23 2016-07-19 Novozymes A/S Polypeptides having glucuronyl esterase activity and polynucleotides encoding same
DK3279320T3 (da) 2012-04-27 2020-03-16 Novozymes Inc GH61-polypeptidvarianter og polynukleotider, som koder for dem
CN104271723B (zh) 2012-05-07 2021-04-06 诺维信公司 具有黄原胶降解活性的多肽以及编码其的核苷酸
WO2013169725A2 (en) 2012-05-08 2013-11-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
SG11201407297VA (en) 2012-05-11 2014-12-30 Codexis Inc Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
US9512413B2 (en) 2012-05-31 2016-12-06 Novozymes A/S Polypeptides having organophosphorous hydrolase activity
US9487767B2 (en) 2012-05-31 2016-11-08 Novozymes A/S of Krogshoejvej 36 Selection in fungi
BR112014031024A2 (pt) 2012-06-11 2017-06-27 Codexis Inc xilanases e xilosidases fúngicas.
CN104508114A (zh) 2012-06-19 2015-04-08 帝斯曼知识产权资产管理有限公司 用于在细胞中表达基因的启动子
WO2013189972A2 (en) 2012-06-20 2013-12-27 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
WO2014009473A1 (en) 2012-07-12 2014-01-16 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
DK2875119T3 (en) 2012-07-19 2018-04-03 Dsm Ip Assets Bv AGSE-DEFICIENT TRIALS
MY175956A (en) 2012-08-16 2020-07-16 Bangladesh Jute Res Institute Cellulose and/or hemicelluloses degrading enzymes from macrophomina phaseolina and uses thereof
KR102043363B1 (ko) 2012-08-16 2019-11-11 방글라데시 주트 리서치 인스티튜트 마크로포미나 파세올리나로부터의 펙틴 분해 효소 및 이의 용도
US9828595B2 (en) 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
EP2885409A1 (en) 2012-08-17 2015-06-24 Novozymes A/S Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
MX2015002099A (es) 2012-08-22 2015-05-11 Dupont Nutrition Biosci Aps Variantes que tienen actividad glucoamilasa.
EP2888360B1 (en) 2012-08-22 2017-10-25 Novozymes A/S Metalloproteases from alicyclobacillus sp.
WO2014029819A1 (en) 2012-08-22 2014-02-27 Novozymes A/S Metalloprotease from exiguobacterium
DK2893012T3 (en) 2012-09-05 2018-12-03 Novozymes As Polypeptides with protease activity
US20140073022A1 (en) 2012-09-10 2014-03-13 Wisconsin Alumni Research Foundation Production of polyhydroxyalkanoates with a defined composition from an unrelated carbon source
CN104685052A (zh) 2012-09-19 2015-06-03 诺维信股份有限公司 用于增强纤维素材料的降解或转化的方法
CN104640990B (zh) 2012-09-19 2017-12-26 帝斯曼知识产权资产管理有限公司 使用必需基因作为标记并任选地将其再循环的细胞修饰方法
CN105861469B (zh) 2012-10-08 2020-04-14 诺维信公司 具有纤维素分解增强活性的多肽以及编码它们的多核苷酸
WO2014056922A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
CN104718286B (zh) 2012-10-12 2018-10-30 诺维信公司 具有过氧合酶活性的多肽
WO2014056916A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056919A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
EP2906688B1 (en) 2012-10-12 2018-08-29 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056917A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
US9453207B2 (en) 2012-10-12 2016-09-27 Novozymes A/S Polypeptides having peroxygenase activity
US20150275194A1 (en) 2012-10-24 2015-10-01 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
EP2922953A4 (en) 2012-11-20 2016-11-09 Shell Int Research PENTOSEFERMENTATION BY A RECOMBINANT MICROORGANISM
WO2014085419A1 (en) 2012-11-29 2014-06-05 The Texas A&M University System Engineering the production of a conformational variant of occidiofungin that has enhanced inhibitory activity against fungal species
CN104837993A (zh) 2012-12-07 2015-08-12 诺维信公司 用于在丝状真菌中产生位点特异性突变的方法
WO2014090161A1 (en) 2012-12-11 2014-06-19 Novozymes A/S Polypeptides having phospholipase c activity and polynucleotides encoding same
CN104870639A (zh) 2012-12-14 2015-08-26 诺维信公司 具有纤维素分解增强活性的多肽以及编码它们的多核苷酸
CA2894261C (en) 2012-12-17 2022-01-04 Novozymes A/S Alpha-amylases and polynucleotides encoding same
WO2014099798A1 (en) 2012-12-19 2014-06-26 Novozymes A/S Polypeptides having cellulolytic enhancinc activity and polynucleotides encoding same
US10023872B2 (en) 2012-12-21 2018-07-17 Novozymes, Inc. Methods for producing heterologous polypeptides in mutants of trichoderma
US9551042B2 (en) 2012-12-21 2017-01-24 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US9902943B2 (en) 2012-12-21 2018-02-27 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
EP2938628A4 (en) 2012-12-24 2016-10-19 Novozymes As POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND POLYNUCLEOTIDES FOR CODING THEREOF
WO2014106593A1 (en) 2013-01-03 2014-07-10 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CA2898495C (en) 2013-01-18 2021-06-01 Codexis, Inc. Engineered biocatalysts useful for carbapenem synthesis
EP3447136B1 (en) 2013-02-04 2020-05-13 DSM IP Assets B.V. Carbohydrate degrading polypeptide and uses thereof
WO2014122161A2 (en) 2013-02-06 2014-08-14 Novozymes A/S Polypeptides having protease activity
ES2694327T3 (es) 2013-02-28 2018-12-19 Codexis, Inc. Polipéptidos de transaminasa modificados por biocatálisis industrial
WO2014138672A1 (en) 2013-03-08 2014-09-12 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
CN105164247A (zh) 2013-03-15 2015-12-16 帝斯曼知识产权资产管理有限公司 嗜热性核酸酶用于降解核酸的用途
WO2014145768A2 (en) 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi
WO2014147127A1 (en) 2013-03-21 2014-09-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP3533866A1 (en) 2013-03-21 2019-09-04 Novozymes A/S Polypeptides having phospholipase a activity and polynucleotides encoding same
WO2014161988A1 (en) 2013-04-05 2014-10-09 Université Du Luxembourg Biotechnological production of itaconic acid
WO2014170218A1 (en) 2013-04-18 2014-10-23 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
MX366196B (es) 2013-04-18 2019-07-01 Codexis Inc Polipeptidos diseñados de fenilalanina amonio liasa.
MX368655B (es) 2013-04-30 2019-10-10 Novozymes As Variantes de glucoamilasa y polinucleótidos que las codifican.
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP2994529B1 (en) 2013-05-10 2018-11-21 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
RU2020101263A (ru) 2013-05-14 2020-02-17 Новозимс А/С Моющие композиции
WO2014183921A1 (en) 2013-05-17 2014-11-20 Novozymes A/S Polypeptides having alpha amylase activity
CN105264058B (zh) 2013-06-06 2022-03-29 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
KR20160029080A (ko) 2013-07-04 2016-03-14 노보자임스 에이/에스 재오염 방지 효과를 가지는 잔탄 분해효소 활성을 가지는 폴리펩티드들 및 이를 암호화하는 폴리뉴클레오티드들
CN105339492A (zh) 2013-07-09 2016-02-17 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
JP2016523552A (ja) 2013-07-10 2016-08-12 ノバルティス アーゲー 多重プロテアーゼ欠損糸状菌細胞及びその使用方法
CA2915336C (en) 2013-07-17 2024-03-12 Novozymes A/S Pullulanase chimeras and polynucleotides encoding same
EP3024930A2 (en) 2013-07-26 2016-06-01 Biomethodes Novel variant trichoderma reesei endoglucanases
EP3033420B1 (en) 2013-08-15 2018-02-21 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
US9708630B1 (en) 2013-10-08 2017-07-18 Wisconsin Alumni Research Foundation Cells and methods for producing fatty alcohols
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
EP3060666B1 (en) 2013-10-25 2020-09-30 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US9822346B2 (en) 2013-11-13 2017-11-21 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
EP3074513A1 (en) 2013-11-26 2016-10-05 Novozymes A/S Enzyme compositions and uses thereof
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
CN105793418A (zh) 2013-11-29 2016-07-20 诺维信公司 过氧合酶变体
DK3077517T3 (en) 2013-12-02 2019-02-11 Dsm Ip Assets Bv ISSTRUCTURING PROTEIN
PT3080254T (pt) 2013-12-11 2024-07-30 Novozymes As Variantes cutinase e polinucleótidos que codificam o mesmo
EP2886656A1 (en) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof
EP3083954B1 (en) 2013-12-20 2018-09-26 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
CN105960457B (zh) 2014-01-22 2021-09-03 诺维信公司 普鲁兰酶变体以及编码它们的多核苷酸
WO2015109972A1 (en) 2014-01-22 2015-07-30 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CN106062276B (zh) 2014-03-05 2019-06-11 诺维信公司 用于将材料功能化并且进行连接的组合物和方法
US20160333292A1 (en) 2014-03-05 2016-11-17 Novozymes A/S Compositions and Methods for Improving Properties of Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
CN106062270A (zh) 2014-03-05 2016-10-26 诺维信公司 使用木葡聚糖内糖基转移酶改进非纤维素纺织材料的性质的组合物和方法
AR099683A1 (es) 2014-03-05 2016-08-10 Novozymes Bioag As Composiciones que comprenden polímeros de xiloglucano como portador para agentes agrícolamente benéficos
US10123535B2 (en) 2014-03-05 2018-11-13 Novozymes A/S Compositions and methods for improving post-harvest properties of agricultural crops
EP3117001B1 (en) 2014-03-12 2019-02-20 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CN106103708A (zh) 2014-04-01 2016-11-09 诺维信公司 具有α淀粉酶活性的多肽
EP3550015B1 (en) 2014-04-10 2021-11-10 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CN106164236B (zh) 2014-04-11 2021-02-02 诺维信公司 洗涤剂组合物
US10030215B2 (en) 2014-04-15 2018-07-24 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
HUE056444T2 (hu) 2014-04-16 2022-02-28 Codexis Inc Génmódosított tirozin-ammónia-liáz
WO2015177153A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
WO2015177152A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
CN106459947B (zh) 2014-05-19 2024-05-14 帝斯曼知识产权资产管理有限公司 脯氨酸特异性内切蛋白酶
CN106459939A (zh) 2014-05-27 2017-02-22 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
WO2015181118A1 (en) 2014-05-27 2015-12-03 Novozymes A/S Methods for producing lipases
BR112016027884B1 (pt) 2014-05-30 2023-05-02 Novozymes A/S Variante de uma xilanase da família 11 de gh genitora, polinucleotídeo, construção de ácido nucleico, vetor de expressão, célula hospedeira, e, métodos de produção de uma variante de xilanase da família 11 de gh e de degradação de um material contendo xilana
WO2015187935A1 (en) 2014-06-06 2015-12-10 Novozymes A/S Enzyme compositions and uses thereof
US10370682B2 (en) 2014-06-25 2019-08-06 Novozymes A/S Xylanase variants and polynucleotides encoding same
WO2016007623A1 (en) 2014-07-09 2016-01-14 Codexis, Inc. Novel p450-bm3 variants with improved activity
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
EP3183339A1 (en) 2014-08-20 2017-06-28 Novozymes A/S Xyloglucan endotransglycosylase variants and polynucleotides encoding same
EP3594335B1 (en) 2014-09-05 2024-05-01 Novozymes A/S Carbohydrate binding module variants and polynucleotides encoding same
WO2016062875A2 (en) 2014-10-23 2016-04-28 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2016071302A1 (en) 2014-11-04 2016-05-12 Novozymes A/S Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed
CN107075489A (zh) 2014-11-20 2017-08-18 诺维信公司 脂环酸芽孢杆菌变体以及编码它们的多核苷酸
DK3224354T3 (da) 2014-11-25 2021-03-01 Codexis Inc Manipulerede iminreductaser og fremgangsmåder til den reduktive aminering af keton- og aminforbindelser
US10781428B2 (en) 2014-12-02 2020-09-22 Novozymes A/S Laccase variants and polynucleotides encoding same
MX388061B (es) 2014-12-05 2025-03-19 Novozymes As Variantes de lipasa y polinucleotidos que las codifican.
WO2016096996A1 (en) 2014-12-16 2016-06-23 Novozymes A/S Polypeptides having n-acetyl glucosamine oxidase activity
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
CN119286826A (zh) 2014-12-19 2025-01-10 诺维信公司 包括具有木聚糖酶活性的多肽和具有阿拉伯呋喃糖苷酶活性的多肽的组合物
US20170360900A1 (en) 2014-12-22 2017-12-21 Codexis, Inc. Human alpha-galactosidase variants
US11396665B2 (en) 2015-01-06 2022-07-26 Dsm Ip Assets B.V. CRISPR-CAS system for a filamentous fungal host cell
WO2016130412A1 (en) 2015-02-10 2016-08-18 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
EP4458964A3 (en) 2015-02-24 2025-03-26 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
EP3262161B1 (en) 2015-02-27 2021-06-30 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
US10385352B2 (en) 2015-03-09 2019-08-20 Novozymes A/S Methods of introducing multiple expression constructs into a eukaryotic cell
WO2016164596A2 (en) 2015-04-07 2016-10-13 Novozymes A/S Methods for selecting enzymes having lipase activity
CN107667177A (zh) 2015-04-07 2018-02-06 诺维信公司 用于选择具有增强活性的酶的方法
AR104205A1 (es) 2015-04-09 2017-07-05 Dsm Ip Assets Bv Fosfolipasa c
KR102604503B1 (ko) 2015-05-07 2023-11-20 코덱시스, 인코포레이티드 페니실린-g 아실라아제
WO2016186948A1 (en) 2015-05-15 2016-11-24 Albert Einstein College Of Medicine, Inc. Gfp-derived fusion tags for protein expression
PT3298138T (pt) 2015-05-22 2022-11-02 Dupont Nutrition Biosci Aps Acetolactato descarboxilase
WO2016188459A1 (en) 2015-05-27 2016-12-01 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
US20180160695A1 (en) 2015-06-02 2018-06-14 Dsm Ip Assets B.V. Use of ice structuring protein afp19 expressed in filamentous fungal strains for preparing food
US10858637B2 (en) 2015-06-16 2020-12-08 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2016205127A1 (en) 2015-06-18 2016-12-22 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
WO2016206621A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Biofinishing system
BR112017028063B1 (pt) 2015-06-26 2022-05-17 Novozymes A/S Método para produção de um extrato de café
WO2017001673A1 (en) 2015-07-01 2017-01-05 Novozymes A/S Methods of reducing odor
MX387681B (es) 2015-07-02 2025-03-18 Novozymes As Composiciones de pienso para animales y uso de las mismas.
EP3950939A3 (en) 2015-07-06 2022-06-08 Novozymes A/S Lipase variants and polynucleotides encoding same
WO2017007547A1 (en) 2015-07-07 2017-01-12 Codexis, Inc. Novel p450-bm3 variants with improved activity
WO2017019491A1 (en) 2015-07-24 2017-02-02 Novozymes Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
BR112018001041A2 (pt) 2015-07-24 2018-09-11 Novozymes Inc polipeptídeo isolado, composição, formulação de caldo inteiro ou composição de cultura de células, célula hospedeira recombinante, métodos para produção de um polipeptídeo e para produção de uma proteína, planta, parte de planta ou célula de planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e para fermentação de um material celulósico ou hemicelulósico.
WO2017017292A1 (es) 2015-07-29 2017-02-02 Abengoa Bioenergía Nuevas Tecnologías, S. A. Expresión de enzimas beta-xilosidasas recombinantes
EP3341475A1 (en) 2015-08-24 2018-07-04 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
RU2720243C2 (ru) 2015-09-02 2020-04-28 ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС Глюкозидгидролазы и их применение в предупреждении и/или лечении патогенной инфекции у животного
WO2017040907A1 (en) 2015-09-04 2017-03-09 Novozymes A/S Methods of inhibiting aa9 lytic polysaccharide monooxygenase catalyzed inactivation of enzyme compositions
WO2017046260A1 (en) 2015-09-17 2017-03-23 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
WO2017050242A1 (en) 2015-09-22 2017-03-30 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
CN116064474A (zh) 2015-10-07 2023-05-05 诺维信公司 多肽
WO2017064253A1 (en) 2015-10-14 2017-04-20 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US10494685B2 (en) 2015-10-14 2019-12-03 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP3362556B1 (en) 2015-10-14 2024-07-10 Novozymes A/S Polypeptide variants
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
CN108138188A (zh) 2015-10-30 2018-06-08 诺维信公司 用于体外和体内表达的多核苷酸构建体
US11001821B2 (en) 2015-11-24 2021-05-11 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
CN108431217B (zh) 2015-12-01 2022-06-21 诺维信公司 用于产生脂肪酶的方法
JP2019500338A (ja) 2015-12-02 2019-01-10 アンスティテュー・ナシオナル・ドゥ・ラ・ルシェルシュ・アグロノミクInstitut National De La Recherche Agronomique 抗菌活性を有する新規ペプチド及びペプチド中におけるl型残基をd型アミノ酸に変換することができる新規酵素
WO2017112847A1 (en) 2015-12-22 2017-06-29 Albumedix A/S Improved protein expression strains
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
JP7626576B2 (ja) 2015-12-30 2025-02-07 ノボザイムス アクティーゼルスカブ 酵素変異体およびこれをコードするポリヌクレオチド
CN108884451A (zh) 2016-01-29 2018-11-23 诺维信公司 β-葡聚糖酶变体以及编码它们的多核苷酸
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
EP3420104A1 (en) 2016-02-23 2019-01-02 Novozymes A/S Improved next-generation sequencing
WO2017151957A1 (en) 2016-03-02 2017-09-08 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
CN109071615A (zh) 2016-03-04 2018-12-21 丹尼斯科美国公司 用于在微生物中产生蛋白质的工程化核糖体启动子
DK3433358T3 (da) 2016-03-24 2022-09-26 Novozymes As Cellobiohydrolasevarianter og polynukleotider, der koder for dem
CN109312333A (zh) 2016-04-07 2019-02-05 诺维信公司 选择具有蛋白酶活性的酶的方法
US10550398B2 (en) 2016-04-19 2020-02-04 Novozymes A/S RlmA-inactivated filamentous fungal host cell
CN109312271A (zh) 2016-04-29 2019-02-05 诺维信公司 洗涤剂组合物及其用途
WO2017191160A1 (en) 2016-05-03 2017-11-09 Novozymes A/S Alpha-amylase variants and polynucleotides encoding the same
EP3452587B1 (en) 2016-05-05 2021-09-08 Codexis, Inc. Penicillin-g acylases
EP3455352A1 (en) 2016-05-09 2019-03-20 Novozymes A/S Variant polypeptides with improved performance and use of the same
EP3246401A1 (en) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives New fatty acid decarboxylase and its uses
CN109196098A (zh) 2016-05-24 2019-01-11 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
EP3462904B1 (en) 2016-05-24 2024-12-18 Novozymes A/S Gastric stable polypeptides having alpha-galactosidase activity and polynucleotides encoding same
MX2018014434A (es) 2016-05-24 2019-03-28 Novozymes As Composiciones que comprenden polipeptidos que tienen actividad galactanasa y polipeptidos que tienen actividad beta-galactosidasa.
WO2017202966A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
WO2017213758A1 (en) 2016-06-09 2017-12-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
WO2017211930A1 (en) 2016-06-10 2017-12-14 Dsm Ip Assets B.V. Mutant lipase and use thereof
WO2017218325A1 (en) 2016-06-15 2017-12-21 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
US10421951B2 (en) 2016-06-22 2019-09-24 Wisconsin Alumni Research Foundation Gene construct encoding mutant thioesterase, mutant thioesterase encoded thereby, transformed host cell containing the gene construct, and method of using them to produce medium-chain fatty acids
EP3263699B1 (en) 2016-06-30 2020-07-01 Fornia BioSolutions, Inc. Novel phytases and uses thereof
BR112018077458A2 (pt) 2016-06-30 2019-04-02 Danisco Us Inc. proteases aspárticas
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
US10662417B2 (en) 2016-07-05 2020-05-26 Novozymes A/S Pectate lyase variants and polynucleotides encoding same
US20190185847A1 (en) 2016-07-06 2019-06-20 Novozymes A/S Improving a Microorganism by CRISPR-Inhibition
JP2019524081A (ja) 2016-07-08 2019-09-05 ノボザイムス アクティーゼルスカブ キシラナーゼ変異体およびそれをコードするポリヌクレオチド
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
US20190352627A1 (en) 2016-07-08 2019-11-21 Novozymes A/S Polypeptides having Xylanase Activity and Polynucleotides Encoding Same
CN109642222A (zh) 2016-07-13 2019-04-16 诺维信公司 食物芽孢杆菌dna酶变体
EP3485008B1 (en) 2016-07-18 2024-01-31 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
CN109477083B (zh) 2016-07-20 2023-06-06 诺维信公司 热稳定性宏基因组碳酸酐酶及其用途
DK3487996T5 (da) 2016-07-21 2024-09-02 Novozymes As Serinproteasevarianter og polynukleotider, der koder for samme
ES2884155T3 (es) 2016-07-21 2021-12-10 Novozymes As Variantes de serina proteasa y polinucleótidos que codifican las mismas
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
EP3487873B1 (en) 2016-07-22 2021-03-31 Novozymes A/S Improved filamentous fungal host
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
CN109563498A (zh) 2016-08-24 2019-04-02 汉高股份有限及两合公司 包含黄原胶裂解酶变体i的洗涤剂组合物
CN109863244B (zh) 2016-08-24 2023-06-06 诺维信公司 Gh9内切葡聚糖酶变体以及编码它们的多核苷酸
EP3504313A1 (en) 2016-08-24 2019-07-03 Henkel AG & Co. KGaA Detergent composition comprising gh9 endoglucanase variants i
WO2018037061A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
JP7316662B2 (ja) 2016-08-26 2023-07-28 コデクシス, インコーポレイテッド 操作されたイミンレダクターゼ、ならびにケトン化合物およびアミン化合物の還元的アミノ化のための方法
WO2018050666A1 (en) 2016-09-15 2018-03-22 Novozymes A/S Genomic integration of dna fragments in fungal host cells
US11578316B2 (en) 2016-09-16 2023-02-14 Dupont Nutrition Biosciences Aps Acetolactate decarboxylase variants having improved specific activity
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
EP3541954A1 (en) 2016-11-21 2019-09-25 Novozymes A/S Yeast cell extract assisted construction of dna molecules
AU2017380488B2 (en) 2016-12-21 2023-09-14 Novozymes A/S Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof
WO2018129130A1 (en) 2017-01-05 2018-07-12 Codexis, Inc. Penicillin-g acylases
WO2018141707A2 (en) 2017-02-01 2018-08-09 Novozymes A/S Alpha-amylase variants
ES2965826T3 (es) 2017-02-01 2024-04-17 Procter & Gamble Composiciones limpiadoras que comprenden variantes de amilasa
AU2018215335B2 (en) 2017-02-03 2020-10-01 Tate & Lyle Solutions Usa Llc Engineered glycosyltransferases and steviol glycoside glucosylation methods
WO2018148633A1 (en) 2017-02-13 2018-08-16 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
ES3014686T3 (en) 2017-02-20 2025-04-24 Novozymes As Lipolytic enzyme for use in baking
CN110505903A (zh) 2017-03-06 2019-11-26 杜邦营养生物科学有限公司 新型真菌岩藻糖苷酶及其在预防和/或治疗动物病原体感染中的用途
WO2018166943A1 (en) 2017-03-13 2018-09-20 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
WO2018172155A1 (en) 2017-03-23 2018-09-27 Novozymes A/S Improved filamentous fungal host cells
EP3601551A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having rnase activity
EP3601550A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having dnase activity
EP3601549A1 (en) 2017-03-31 2020-02-05 Novozymes A/S Polypeptides having dnase activity
CN110651040A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
BR112019020772A2 (pt) 2017-04-03 2020-04-28 Novozymes A/S processo de recuperação
WO2018185152A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptide compositions and uses thereof
WO2018185150A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptides
CN110651029B (zh) 2017-04-04 2022-02-15 诺维信公司 糖基水解酶
EP3610027A1 (en) 2017-04-11 2020-02-19 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2018200214A2 (en) 2017-04-27 2018-11-01 Codexis, Inc. Ketoreductase polypeptides and polynucleotides
CN120005686A (zh) 2017-05-05 2025-05-16 诺维信公司 包含脂肪酶和亚硫酸根的组合物
EP3622064B1 (en) 2017-05-08 2025-05-14 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
CA3062550A1 (en) 2017-05-08 2018-11-15 Codexis, Inc. Engineered ligase variants
WO2018206302A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
CN111032682B (zh) 2017-06-14 2024-04-12 科德克希思公司 用于工业生物催化的工程化转氨酶多肽
DK3642343T3 (en) 2017-06-20 2022-03-14 Albumedix Ltd Improved protein expression strains
WO2018234465A1 (en) 2017-06-22 2018-12-27 Novozymes A/S Xylanase variants and polynucleotides encoding same
EP3645713A4 (en) 2017-06-27 2021-06-30 Codexis, Inc. PENICILLIN-G ACYLASES
WO2019005755A1 (en) 2017-06-28 2019-01-03 Novozymes A/S POLYPEPTIDES HAVING TREHALASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
RU2020103727A (ru) 2017-06-30 2021-07-30 Кодексис, Инк. Варианты рнк-полимеразы т7
AU2018292105B2 (en) 2017-06-30 2024-12-12 Codexis, Inc. T7 RNA polymerase variants
US11746366B2 (en) 2017-07-24 2023-09-05 Novozymes A/S GH5 and GH30 in wet milling
CN111132996A (zh) 2017-07-28 2020-05-08 普林斯顿大学理事会 用于重组蛋白表达的融合标签
US10081800B1 (en) 2017-08-03 2018-09-25 Fornia Biosolutions, Inc. Lactonase enzymes and methods of using same
EP3665275A1 (en) 2017-08-08 2020-06-17 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
WO2019038059A1 (en) 2017-08-24 2019-02-28 Henkel Ag & Co. Kgaa DETERGENT COMPOSITIONS COMPRISING GH9 ENDOGLUCANASE VARIANTS II
CN111278971A (zh) 2017-08-24 2020-06-12 诺维信公司 Gh9内切葡聚糖酶变体以及编码它们的多核苷酸
US11359188B2 (en) 2017-08-24 2022-06-14 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
WO2019038060A1 (en) 2017-08-24 2019-02-28 Henkel Ag & Co. Kgaa DETERGENT COMPOSITION COMPRISING XANTHANE LYASE II VARIANTS
KR20200044920A (ko) * 2017-08-30 2020-04-29 서스테이너블 바이오프로덕츠, 인크. 사상균을 함유하는 식용 조성물 및 이의 배양을 위한 생물 반응기 시스템
AU2018322867B2 (en) 2017-09-01 2024-05-09 Novozymes A/S Animal feed additives comprising a polypeptide having protease activity and uses thereof
BR112020001577B1 (pt) 2017-09-01 2023-12-26 Novozymes A/S Aditivo de ração animal, formulação líquida, ração animal, métodos para melhoria de um ou mais parâmetros de desempenho de um animal, para preparação de uma ração animal, para o tratamento de proteínas, para aumento da digestibilidade e/ou solubilidade da proteína, para melhoria do valor nutricional de uma ração animal e para produção de um polipeptídeo, e, uso do aditivo de ração animal
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
WO2019063613A1 (en) 2017-09-26 2019-04-04 Dsm Ip Assets B.V. ENZYMATIC ELIMINATION OF CHLOROPHYLL SUBSTRATES FROM TRIACYLGLYCEROL OILS
US11332725B2 (en) 2017-09-27 2022-05-17 Novozymes A/S Lipase variants and microcapsule compositions comprising such lipase variants
EP3461892A3 (en) 2017-09-27 2019-06-12 The Procter & Gamble Company Detergent compositions comprising lipases
WO2019068713A1 (en) 2017-10-02 2019-04-11 Novozymes A/S POLYPEPTIDES HAVING MANNANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING THESE POLYPEPTIDES
BR112020006621A2 (pt) 2017-10-02 2020-10-06 Novozymes A/S polipeptídeos com atividade de mananase e polinucleotídeos codificando os mesmos
EP3701016A1 (en) 2017-10-27 2020-09-02 Novozymes A/S Dnase variants
HUE057471T2 (hu) 2017-10-27 2022-05-28 Procter & Gamble Polipeptid-variánsokat tartalmazó mosószerkészítmények
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
EP3706780A4 (en) 2017-11-07 2021-12-22 Codexis, Inc. TRANSGLUTAMINASE VARIANTS
EP3707252A1 (en) 2017-11-10 2020-09-16 Novozymes A/S Temperature-sensitive cas9 protein
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
EP3485734A1 (en) 2017-11-21 2019-05-22 Technische Universität München Method for preparing food products comprising rye
EP3488854A1 (en) 2017-11-22 2019-05-29 Technische Universität München Method for preparing xyloglucan-oligosaccharides
US11725197B2 (en) 2017-12-04 2023-08-15 Novozymes A/S Lipase variants and polynucleotides encoding same
SG11202004185PA (en) 2017-12-13 2020-06-29 Codexis Inc Carboxyesterase polypeptides for amide coupling
US11408009B2 (en) 2017-12-18 2022-08-09 Whitehead Institute For Biomedical Research Host cell expression of 4-hydroxyphenylacetaldehyde synthase for production of salidroside, icariside D2, and precursors
EP3502242A1 (en) 2017-12-20 2019-06-26 Technische Universität München New xylanase with improved thermostability and increased enzyme activity on arabinoxylan
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
WO2019154954A1 (en) 2018-02-08 2019-08-15 Novozymes A/S Lipase variants and compositions thereof
CN111868239A (zh) 2018-02-08 2020-10-30 诺维信公司 脂肪酶、脂肪酶变体及其组合物
EP3530744A1 (en) 2018-02-23 2019-08-28 University of Limerick A polypeptide having xylanase and/or cellulase activity
CN112105740A (zh) 2018-02-23 2020-12-18 诺维信公司 真菌宿主中的长链非编码rna表达
EP3775222B1 (en) 2018-03-26 2024-01-03 Novozymes A/S Fungal chaperone proteins
US11535837B2 (en) 2018-03-29 2022-12-27 Novozymes A/S Mannanase variants and polynucleotides encoding same
MX2020010526A (es) 2018-04-09 2021-01-08 Novozymes As Polipéptidos que tienen actividad alfa-amilasa ypolinucleótidos que los codifican.
WO2019201783A1 (en) 2018-04-19 2019-10-24 Novozymes A/S Stabilized cellulase variants
WO2019201785A1 (en) 2018-04-19 2019-10-24 Novozymes A/S Stabilized cellulase variants
CA3100615A1 (en) 2018-05-18 2019-11-21 Dsm Ip Assets B.V. Mutant lipase and use thereof
KR20210013585A (ko) 2018-05-18 2021-02-04 디에스엠 아이피 어셋츠 비.브이. 돌연변이체 리파아제 및 이의 용도
US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
JP7461658B2 (ja) 2018-07-09 2024-04-04 コデクシス, インコーポレイテッド 操作されたプリンヌクレオシドホスホリラーゼバリアント酵素
MX2021000328A (es) 2018-07-09 2021-03-25 Codexis Inc Enzimas de variantes de galactosa oxidasa modificadas geneticamente.
AU2019300836B2 (en) 2018-07-09 2025-09-04 Codexis, Inc. Engineered deoxyribose-phosphate aldolases
SG11202012109UA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered phosphopentomutase variant enzymes
EP3820991A4 (en) 2018-07-09 2022-07-06 Codexis, Inc. MANIPULATED ENZYMES WITH PANTOTHENATE KINASE VARIANTS
WO2020012266A1 (en) 2018-07-12 2020-01-16 Novartis Ag Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase
CN112672989A (zh) 2018-07-12 2021-04-16 科德克希思公司 工程化苯丙氨酸氨裂合酶多肽
BR112021001661A8 (pt) 2018-07-30 2022-08-09 Codexis Inc Glicosiltransferase modificada, polinucleotídeo modificado, vetor, célula hospedeira, métodos para produzir pelo menos uma glicosiltransferase modificada, para produzir pelo menos uma variante de sacarose sintase, para glicosilação de um substrato, para produzir rebaudiosídeo m, rebaudiosídeo a e/ou rebaudiosídeo i e rebaudiosídeo d, composição, sacarose sintase modificada, pelo menos um rebaudiosídeo, rebaudiosídeo m, rebaudiosídeo a, rebaudiosídeo i, e, rebaudiosídeo d.
EP3830261A1 (en) 2018-08-02 2021-06-09 Novozymes A/S Preparation of combinatorial libraries of dna constructs using introns
CN112566502B (zh) 2018-08-31 2025-02-18 诺维信公司 具有蛋白酶活性的多肽以及编码它们的多核苷酸
CN113056476A (zh) 2018-10-03 2021-06-29 诺维信公司 具有α-甘露聚糖降解活性的多肽以及编码它们的多核苷酸
EP3864136A1 (en) 2018-10-09 2021-08-18 Novozymes A/S Modified filamentous fungal host cell
KR20210084590A (ko) 2018-10-29 2021-07-07 코덱시스, 인코포레이티드 조작된 dna 중합효소 변이체
US20220010305A1 (en) 2018-10-31 2022-01-13 Novozymes A/S Genome Editing by Guided Endonuclease and Single-stranded Oligonucleotide
US20220025422A1 (en) 2018-11-28 2022-01-27 Novozymes A/S Improved Filamentous Fungal Host Cells
BR112021010338A2 (pt) 2018-11-28 2021-11-16 Novozymes As Células hospedeiras fúngicas filamentosas modificadas
US20220145339A1 (en) 2018-12-10 2022-05-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for preparation of primary amine compounds
CN113302305A (zh) 2018-12-12 2021-08-24 诺维信公司 提高丝状真菌细胞在多肽的产生方面的生产力的方法
CN113302293A (zh) 2018-12-12 2021-08-24 诺维信公司 具有木聚糖酶活性的多肽以及编码这些多肽的多核苷酸
EP3893860A4 (en) 2018-12-14 2023-03-29 Codexis, Inc. ENGINEERED TYROSINE AMMONIA LYASE
US11427813B2 (en) 2018-12-20 2022-08-30 Codexis, Inc. Human alpha-galactosidase variants
CN113316641B (zh) 2018-12-21 2025-01-28 诺维信公司 串联蛋白表达
US11959111B2 (en) 2018-12-21 2024-04-16 Novozymes A/S Polypeptides having peptidoglycan degrading activity and polynucleotides encoding same
EP3908654A1 (en) 2019-01-11 2021-11-17 River Stone Biotech ApS Recombinant host cells with improved production of l-dopa, dopamine, (s)-norcoclaurine or derivatives thereof
WO2020161354A1 (en) 2019-02-08 2020-08-13 Pili Recombinant host cells to produce anthraquinone derivatives
WO2020173817A1 (en) 2019-02-28 2020-09-03 Novozymes A/S Calcite binding proteins
JP2022525057A (ja) 2019-03-08 2022-05-11 ダニスコ・ユーエス・インク 融合ポリペプチド
MX2021011166A (es) 2019-03-18 2021-10-22 Novozymes As Polipeptidos que tienen actividad pululanasa adecuados para usarse en licuefaccion.
WO2020190323A1 (en) 2019-03-21 2020-09-24 Fornia Biosolutions, Inc. Additional phytase variants and methods
US11098265B2 (en) 2019-03-27 2021-08-24 Bunge Global Innovation, Llc Silica adsorbent treatment for removal of chlorophyll derivatives from triacylglycerol-based oils
JP7662531B2 (ja) 2019-03-28 2025-04-15 ダニスコ・ユーエス・インク 改変抗体
EP3947619A1 (en) 2019-04-03 2022-02-09 Novozymes A/S Polypeptides having beta-glucanase activity, polynucleotides encoding same and uses thereof in cleaning and detergent compositions
WO2020207944A1 (en) 2019-04-10 2020-10-15 Novozymes A/S Polypeptide variants
BR112021020439A2 (pt) 2019-04-12 2022-05-24 Novozymes As Variantes estabilizadas de glicosídeo hidrolase
EP3963057A4 (en) 2019-05-01 2023-06-14 Codexis, Inc. MANIPULATED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
US12215359B2 (en) 2019-05-01 2025-02-04 Codexis, Inc. Engineered glucose dehydrogenases and methods for the reductive amination of ketone and amine compounds
EP3969576A1 (en) 2019-05-15 2022-03-23 Novozymes A/S Temperature-sensitive rna-guided endonuclease
WO2020239784A1 (en) 2019-05-27 2020-12-03 Octarine Bio Ivs Genetically modified host cells producing glycosylated cannabinoids.
CA3141660A1 (en) 2019-06-24 2020-12-30 The Procter & Gamble Company Cleaning compositions comprising amylase variants
EP3987022A1 (en) 2019-06-24 2022-04-27 Novozymes A/S Alpha-amylase variants
US20220298517A1 (en) 2019-06-25 2022-09-22 Novozymes A/S Counter-selection by inhibition of conditionally essential genes
US12480104B2 (en) 2019-07-02 2025-11-25 Codexis, Inc. Engineered sucrose phosphorylase variant enzymes
CA3142162A1 (en) 2019-07-02 2021-01-07 Codexis, Inc. Engineered acetate kinase variant enzymes
WO2021001400A1 (en) 2019-07-02 2021-01-07 Novozymes A/S Lipase variants and compositions thereof
US20220267783A1 (en) 2019-07-25 2022-08-25 Novozymes A/S Filamentous fungal expression system
EP4004187A1 (en) 2019-07-26 2022-06-01 Novozymes A/S Modified filamentous fungal host cell
US11987823B2 (en) 2019-08-30 2024-05-21 Societe Des Produits Nestle S.A. Engineered lipase variants
WO2021048172A2 (en) 2019-09-09 2021-03-18 River Stone Biotech Aps Delivery vehicle for in situ delivering of pharmaceutical agents
WO2021050348A1 (en) 2019-09-12 2021-03-18 Codexis, Inc. Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine
WO2021055395A1 (en) 2019-09-16 2021-03-25 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
US20210094986A1 (en) 2019-09-27 2021-04-01 The Procter & Gamble Company Consumer product compositions comprising fatty acid photodecarboxyalases
EP4038170A1 (en) 2019-10-03 2022-08-10 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
AU2020372776A1 (en) 2019-10-28 2022-04-28 Danisco Us Inc. Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases
US20210139879A1 (en) 2019-10-31 2021-05-13 The Procter & Gamble Company Consumer Product Compositions Comprising P450 Fatty Acid Decarboxylases
JP7720098B2 (ja) 2019-11-26 2025-08-07 コデクシス, インコーポレイテッド 化合物のヒドロキシル化のための生体触媒および方法
AR120801A1 (es) 2019-12-19 2022-03-16 Novozymes As Variantes de xilanasa y polinucleótidos que codifican las mismas
US20220411773A1 (en) 2019-12-20 2022-12-29 Novozymes A/S Polypeptides having proteolytic activity and use thereof
CA3165484A1 (en) 2019-12-20 2021-06-24 Codexis, Inc. Engineered acid alpha-glucosidase variants
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
CN115052981A (zh) 2020-01-31 2022-09-13 诺维信公司 甘露聚糖酶变体以及编码它们的多核苷酸
WO2021152120A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2021158686A1 (en) 2020-02-04 2021-08-12 Codexis, Inc. Engineered leucine decarboxylases
MX2022009515A (es) 2020-02-10 2022-09-02 Novozymes As Variantes de alfa-amilasa y polinucleotidos que las codifican.
EP4103709A2 (en) 2020-02-10 2022-12-21 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
US12359182B2 (en) 2020-02-26 2025-07-15 Novozymes A/S Polypeptide variants
US20250179528A1 (en) 2020-03-12 2025-06-05 Novozymes A/S Crispr-aid using catalytically inactive rna-guided endonuclease
WO2021202473A2 (en) 2020-03-30 2021-10-07 Danisco Us Inc Engineered antibodies
EP3892708A1 (en) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Cleaning compositions comprising dispersin variants
CN115210371A (zh) 2020-04-08 2022-10-18 诺维信公司 碳水化合物结合模块变体
CA3179751A1 (en) 2020-04-10 2021-10-14 Codexis, Inc. Engineered transaminase polypeptides
CA3175523A1 (en) 2020-04-13 2021-10-21 Antti Virtanen Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
EP4139431A1 (en) 2020-04-21 2023-03-01 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
EP4153765A1 (en) 2020-05-20 2023-03-29 Wisconsin Alumni Research Foundation Cells and methods for producing methyl ketones
EP4193149A1 (en) 2020-08-04 2023-06-14 Abbott Laboratories Improved methods and kits for detecting sars-cov-2 protein in a sample
CA3189083A1 (en) 2020-08-13 2022-02-17 Novozymes A/S Phytase variants and polynucleotides encoding same
WO2022043321A2 (en) 2020-08-25 2022-03-03 Novozymes A/S Variants of a family 44 xyloglucanase
CA3191867A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered protease variants
CA3191900A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered amylase variants
CN116323932A (zh) 2020-08-28 2023-06-23 诺维信公司 具有改善的溶解度的蛋白酶变体
US20220112446A1 (en) 2020-10-09 2022-04-14 The Procter & Gamble Company Cleaning composition comprising an alpha-dioxygenase
EP4229189A1 (en) 2020-10-13 2023-08-23 Novozymes A/S Glycosyltransferase variants for improved protein production
US20240035005A1 (en) 2020-10-29 2024-02-01 Novozymes A/S Lipase variants and compositions comprising such lipase variants
US20230399632A1 (en) 2020-11-02 2023-12-14 Novozymes A/S Glucoamylase Variants and Polynucleotides Encoding Same
EP4237430A1 (en) 2020-11-02 2023-09-06 Novozymes A/S Leader peptides and polynucleotides encoding the same
EP4026900A3 (en) 2020-12-17 2022-10-05 Fornia BioSolutions, Inc. Xylanase variants and methods
US11898174B2 (en) 2020-12-18 2024-02-13 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
WO2022147147A1 (en) 2020-12-30 2022-07-07 Abbott Laboratories Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
AR124921A1 (es) 2021-02-18 2023-05-17 Novozymes As Polipéptidos inactivos que contienen hemo
WO2022189521A1 (en) 2021-03-12 2022-09-15 Novozymes A/S Polypeptide variants
US20240060061A1 (en) 2021-03-15 2024-02-22 Novozymes A/S Dnase variants
WO2022197512A1 (en) 2021-03-15 2022-09-22 The Procter & Gamble Company Cleaning compositions containing polypeptide variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
CA3215105A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered acetate kinase variant enzymes
IL305922A (en) 2021-04-02 2023-11-01 Codexis Inc Transgenic enzymes of variant guanylate kinase
WO2022212832A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered cyclic gmp-amp synthase (cgas) variant enzymes
WO2022212824A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered adenylate kinase variant enzymes
EP4334441A1 (en) 2021-05-07 2024-03-13 River Stone Biotech ApS Glycosylated opioids
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
EP4347813A1 (en) 2021-05-27 2024-04-10 Novozymes A/S Transcriptional regulators and polynucleotides encoding the same
WO2022268885A1 (en) 2021-06-23 2022-12-29 Novozymes A/S Alpha-amylase polypeptides
WO2023006699A1 (en) 2021-07-30 2023-02-02 Københavns Universitet Cells and method for producing isoprenoid molecules with canonical and non-canonical structures
US20230089159A1 (en) 2021-09-16 2023-03-23 The Procter & Gamble Company Cleaning composition comprising an engineered fatty acid alpha-dioxygenase
WO2023064938A1 (en) 2021-10-15 2023-04-20 Codexis, Inc. Engineered dna polymerase variants
WO2024015953A1 (en) 2022-07-15 2024-01-18 Danisco Us Inc. Methods for producing monoclonal antibodies
WO2024100063A1 (en) 2022-11-08 2024-05-16 River Stone Biotech Aps Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression
CN120187847A (zh) 2022-11-17 2025-06-20 瑞康贝生物科学公司 用于生物合成天麻素的构建体和方法
EP4649143A1 (en) 2023-01-12 2025-11-19 Novartis AG Engineered ketoreductase polypeptides
WO2025012325A1 (en) 2023-07-11 2025-01-16 Dsm Ip Assets B.V. Protein arginine deiminase
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE35176B1 (en) * 1970-05-14 1975-11-26 Ranks Hovis Mcdougall Ltd Improvements in the production of edible protein containing substances
US3937654A (en) * 1970-05-14 1976-02-10 Ranks Hovis Mcdougall Limited Production of edible protein substances
US4163692A (en) * 1977-04-25 1979-08-07 E. I. Du Pont De Nemours And Company Low phosphate growth of fungal mycelia
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
US5070020A (en) * 1988-05-09 1991-12-03 Eli Lilly And Company Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase
GB8904762D0 (en) * 1989-03-02 1989-04-12 Glaxo Group Ltd Biological process
GB9011347D0 (en) * 1990-05-21 1990-07-11 Ici Plc Production of a proteinaceous composition
CA2069147A1 (en) * 1991-05-22 1992-11-23 Kazuaki Kitano Dna and its use
FR2681076B1 (fr) * 1991-09-06 1994-11-18 Sanofi Elf Adn recombinant codant pour une proteine a activite endochitinase.
US5360901A (en) * 1992-03-04 1994-11-01 Genencor International, Inc. Gene sequence encoding Aspergillus niger catalase-R

Also Published As

Publication number Publication date
US5837847A (en) 1998-11-17
EP1559776A3 (en) 2006-01-11
JP2001169791A (ja) 2001-06-26
JPH10500024A (ja) 1998-01-06
WO1996000787A1 (en) 1996-01-11
AU2705895A (en) 1996-01-25
FI119437B (fi) 2008-11-14
FI965220A0 (fi) 1996-12-27
ATE294871T1 (de) 2005-05-15
CN101659926A (zh) 2010-03-03
EP0777737A1 (en) 1997-06-11
JP3511005B2 (ja) 2004-03-29
CN1151762A (zh) 1997-06-11
DE69534185T2 (de) 2006-02-23
JP3167729B2 (ja) 2001-05-21
EP0777737B1 (en) 2005-05-04
DE69534185D1 (de) 2005-06-09
EP1559776A2 (en) 2005-08-03

Similar Documents

Publication Publication Date Title
FI965220L (fi) Ei-toksinen, ei-toksigeeninen, ei-patogeeninen Fusarium-ilmentämissysteemi ja siinä käytettävät promootterit ja terminaattorit
NO953755D0 (no) Kronestabilisert, kombinert kjerne- og boresystem
TR199600077A2 (tr) Tampon uygulayici.
FR2708199B1 (fr) Nouvelles compositions cosmétiques et utilisations.
FI963904L (fi) Tuote, menetelmä sen valmistamiseksi ja sen käyttö
PL320692A1 (en) Novel anticoagulant, method of obtaining same and application thereof
FI962350L (fi) BPM-12, BMP-13 sekä niiden jännettä indusoivat koostumukset
NO976031L (no) Lavviskös, höykonsentrert friksjonsreduserende middel og fremstilling derav
NL1001338A1 (nl) 2-Hydroxyfenyltriazinen, werkwijze ter bereiding daarvan alsmede de toepassing van UV-absorbeermiddelen.
EE04500B1 (et) Trombiini inhibiitorid, nende saamine ja kasutamine
FI843716A7 (fi) Pyridiiniliukoista uutetta ja puhdistettua, myrkyttömäksi tehtyä endotoksiinia sisältävä koostumus ja sen käyttö.
FI951817A7 (fi) Orgonaluminoksituote, sen valmistus ja käyttö
FI970094A7 (fi) Substituoidut bentsamidiinit, niiden valmistus ja käyttö lääkeaineena
DK0776363T3 (da) Ribozymbibliotek, fremstilling og anvendelse heraf
BR9506430A (pt) Agente flavorizante
DE69514239D1 (de) Sequenzielle, selektive betätigung von flugzeugbremsen
DK0910369T3 (da) Benzothiophener, formuleringer indeholdende samme og fremgangsmåder
DE69511323D1 (de) Emulsionspolymerisationsinhibitor und Suspensionspolymerisationsverfahren, die diesen Verwenden
NO983802D0 (no) Benzothiofener, formuleringer inneholdende samme og fremgangsmÕter
BR9304741A (pt) Agente de lavagem, sua aplicação e sua preparação
GB9420616D0 (en) Method, compositions and use
FI944563L (fi) Mikro-organismeja, valmistusmenetelmä ja käyttö
FI965172L (fi) Uusia amido-kinoksaliinidioneja, niiden valmistus ja käyttö
FI970219L (fi) Katalyytti, sen käyttö, sekä menetelmä sen valmistamiseksi
DK0777737T3 (da) Non-toksisk, non-toksigent, non-patogent Fusarium ekspressionssystem og promoterer og terminatorer til anvendelse deri

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 119437

Country of ref document: FI

MA Patent expired