MX375798B - Endoproteasa específica para prolina. - Google Patents

Endoproteasa específica para prolina.

Info

Publication number
MX375798B
MX375798B MX2016015036A MX2016015036A MX375798B MX 375798 B MX375798 B MX 375798B MX 2016015036 A MX2016015036 A MX 2016015036A MX 2016015036 A MX2016015036 A MX 2016015036A MX 375798 B MX375798 B MX 375798B
Authority
MX
Mexico
Prior art keywords
polypeptide
seq
proline
sequence
specific endoprotease
Prior art date
Application number
MX2016015036A
Other languages
English (en)
Other versions
MX2016015036A (es
Inventor
Bruine-Paulus Angela De
Chantal Christis
Der Laan Jan Metske Van
Johanna Henrica Gerdina Maria Mutsaers
Martine Spaans
De Vondervoort Peter Jozef Ida Van
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MX2016015036A publication Critical patent/MX2016015036A/es
Publication of MX375798B publication Critical patent/MX375798B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/347—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of proteins from microorganisms or unicellular algae
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/66—Proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/70—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter
    • A23L2/84—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter using microorganisms or biological material, e.g. enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/195—Proteins from microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/101—Addition of antibiotics, vitamins, amino-acids, or minerals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21026—Prolyl oligopeptidase (3.4.21.26), i.e. proline-specific endopeptidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

La presente invención se relaciona con un polipéptido que tiene actividad de endoproteasa específica para prolina, seleccionado del grupo consistente de i. un polipéptido que comprende una secuencia de polipéptido madura de SEQ ID NO: 2; ii. un polipéptido que tiene al menos 70%, 75%, 80%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, de identidad con la secuencia de polipéptido maduro de SEQ ID NO: 2; iii. un polipéptido codificado por un ácido nucleico que hibrida bajo restricción media, preferiblemente bajo condiciones de restricción alta a la cadena complementaria de la secuencia de codificación del polipéptido maduro de SEQ ID NO:1; iv. un polipéptido codificado por un ácido nucleico que tiene al menos 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% o 100% de identidad con la secuencia de codificación de polipéptido maduro de SEQ ID NO: 1. La invención se relaciona adicionalmente con un método para producir el polipéptido y un proceso para la preparación de un producto alimenticio o de pienso en donde se utiliza el polipéptido.
MX2016015036A 2014-05-19 2015-05-19 Endoproteasa específica para prolina. MX375798B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14168866 2014-05-19
PCT/EP2015/061026 WO2015177171A1 (en) 2014-05-19 2015-05-19 Proline-specific endoprotease

Publications (2)

Publication Number Publication Date
MX2016015036A MX2016015036A (es) 2017-05-02
MX375798B true MX375798B (es) 2025-03-07

Family

ID=50732004

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015036A MX375798B (es) 2014-05-19 2015-05-19 Endoproteasa específica para prolina.

Country Status (11)

Country Link
US (1) US10450554B2 (es)
EP (1) EP3146043B1 (es)
JP (1) JP6601630B2 (es)
CN (1) CN106459947B (es)
BR (1) BR112016026789B1 (es)
DK (1) DK3146043T3 (es)
EA (1) EA034253B1 (es)
ES (1) ES2744898T3 (es)
MX (1) MX375798B (es)
PL (1) PL3146043T3 (es)
WO (1) WO2015177171A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106459948B (zh) * 2014-06-03 2020-12-29 帝斯曼知识产权资产管理有限公司 脯氨酸特异性内切蛋白酶及其用途
EP3596199A1 (en) 2017-03-13 2020-01-22 DSM IP Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
EP4525626A1 (en) 2022-05-16 2025-03-26 DSM IP Assets B.V. Lipolytic enzyme variants
EP4743572A1 (en) 2023-07-11 2026-05-20 DSM IP Assets B.V. ARGININE PROTEIN DEIMINASE

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
PL336345A1 (en) 1997-04-11 2000-06-19 Dsm Nv Genic conversion as a tool for constructing recombined filiform fungi
ES2287989T3 (es) 1997-12-22 2007-12-16 Dsm Ip Assets B.V. Clonacion de expresion en hongos filamentosos.
EP1194572A2 (en) 1999-03-22 2002-04-10 Novozymes Biotech, Inc. Promoter sequences derived from fusarium venenatum and uses thereof
DK1339837T3 (da) * 2000-12-07 2008-06-09 Dsm Ip Assets Bv Prolyl-endoprotease fra Aspergillus Niger
DE60103174T2 (de) * 2000-12-07 2005-05-12 Dsm Ip Assets B.V. Verfahren zur verhinderung oder verminderung der trübung in getränken
AU2003215272B2 (en) 2002-02-14 2008-04-03 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
CA2490020C (en) 2002-06-07 2011-01-04 Dsm Ip Assets B.V. Improved method for the prevention or reduction of haze in beverages
US8524225B2 (en) 2003-09-23 2013-09-03 Dsm Ip Assets B.V. Use of proline specific endoproteases to hydrolyse peptides and proteins
DK2410048T3 (en) 2005-01-24 2016-11-28 Dsm Ip Assets Bv A process for the preparation of a compound of interest in a filamentous fungal cell
CA2657975A1 (en) 2006-06-29 2008-01-03 Dsm Ip Assets B.V. A method for achieving improved polypeptide expression
EP2402425B1 (en) 2006-07-13 2021-04-14 DSM IP Assets B.V. Improved brewing process
EP2222835A1 (en) * 2007-11-23 2010-09-01 DSM IP Assets B.V. Improved bioactive peptide production
TW201000634A (en) 2008-05-30 2010-01-01 Dsm Ip Assets Bv Proline-specific protease
WO2010121933A1 (en) 2009-04-22 2010-10-28 Dsm Ip Assets B.V. Process for the production of a recombinant polypeptide of interest
WO2011009700A1 (en) 2009-07-22 2011-01-27 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
US20140205587A1 (en) * 2011-06-17 2014-07-24 Alvine Pharmaceuticals, Inc. Proteases for Degrading Gluten
WO2013007821A1 (en) 2011-07-14 2013-01-17 Dsm Ip Assets B.V. Screening method
US9631197B2 (en) * 2012-03-12 2017-04-25 Dsm Ip Assets B.V. Rasamsonia transformants
CN104619853B (zh) 2012-04-23 2021-10-12 帝斯曼知识产权资产管理有限公司 多肽表达方法
WO2014202622A2 (en) * 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof

Also Published As

Publication number Publication date
PL3146043T3 (pl) 2019-12-31
EP3146043A1 (en) 2017-03-29
BR112016026789A2 (pt) 2017-12-12
US10450554B2 (en) 2019-10-22
ES2744898T3 (es) 2020-02-26
EP3146043B1 (en) 2019-06-26
MX2016015036A (es) 2017-05-02
JP6601630B2 (ja) 2019-11-06
DK3146043T3 (da) 2019-09-23
US20170081651A1 (en) 2017-03-23
JP2017515467A (ja) 2017-06-15
CN106459947B (zh) 2024-05-14
EA034253B1 (ru) 2020-01-22
BR112016026789B1 (pt) 2023-05-02
EA201692327A1 (ru) 2017-02-28
CN106459947A (zh) 2017-02-22
WO2015177171A1 (en) 2015-11-26

Similar Documents

Publication Publication Date Title
WO2016183438A8 (en) Self-targeting genome editing system
MX2018016114A (es) Una novedosa fructosa-6-fosfato-3-epimerasa termoestable y un procedimiento para producir alulosa mediante el uso de la misma.
SA518400053B1 (ar) عملية مُحسنة لإنتاج حمض أكريليك
SA517390635B1 (ar) أنظمة وطرق لإنتاج البروبيلين
MX376332B (es) Endoproteasa especifica para prolina y usos de la misma.
SG10201900355RA (en) Polypeptide for hydrolytic cleavage of zearalenone and/orzearalenone derivatives, isolated polynucleotide thereof as wellas a polypeptide containing an additive, use of same as well as aprocess
MX2022005119A (es) Metodos de reduccion de olor.
NZ629051A (en) Glyphosate resistant plants and associated methods
EP3708660A3 (en) Polypeptides
IN2012DN01652A (es)
MY189932A (en) Recombinant microorganism for improved production of alanine
WO2014202622A3 (en) Rasamsonia gene and use thereof
MY175904A (en) Method for the fermentative production of l-amino acids using improved strains of the enterobacteriaceae family
EP3760713A3 (en) Lipase variants and polynucleotides encoding same
BR112016020517A2 (pt) método de produção de lipídeo através da utilização de ss-cetoacil-acp sintase
NZ742745A (en) Variants of chymosin with improved milk-clotting properties
MX2016009149A (es) Variantes mejoradas de enzimas.
MX377843B (es) Uso de una xilanasa en maíz y sub-productos de maíz.
RU2016130093A (ru) Трансформант для экспрессии цис-пренилтрансферазы и рецептора Nogo-B
AT516457A3 (de) Polypeptid zur enzymatischen Detoxifizierung von Zearalenon, sowie isoliertes Polynukleotid, sowie Zusatzstoff, Verwendung und Verfahren desselben
IN2015DN03206A (es)
MX382209B (es) Proteina bioactiva, uso de esta y metodo para su produccion.
PH12017501678A1 (en) Recombinant microorganism for improved production of finie chemicals
EA201692327A1 (ru) Пролин-специфическая эндопротеаза
PH12018500069A1 (en) Novel lactobacillus sp. microorganisms, and composition for animal feed comprising same

Legal Events

Date Code Title Description
FG Grant or registration