DK0815246T3 - Fremgangsmåder og sammensætninger til sekretion af heterologe polypeptider - Google Patents

Fremgangsmåder og sammensætninger til sekretion af heterologe polypeptider

Info

Publication number
DK0815246T3
DK0815246T3 DK96906659T DK96906659T DK0815246T3 DK 0815246 T3 DK0815246 T3 DK 0815246T3 DK 96906659 T DK96906659 T DK 96906659T DK 96906659 T DK96906659 T DK 96906659T DK 0815246 T3 DK0815246 T3 DK 0815246T3
Authority
DK
Denmark
Prior art keywords
secretion
polypeptide
interest
compositions
methods
Prior art date
Application number
DK96906659T
Other languages
Danish (da)
English (en)
Inventor
Laura C Simmons
Daniel G Yansura
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0815246T3 publication Critical patent/DK0815246T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Electrotherapy Devices (AREA)
  • External Artificial Organs (AREA)
DK96906659T 1995-03-01 1996-02-27 Fremgangsmåder og sammensætninger til sekretion af heterologe polypeptider DK0815246T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/398,615 US5840523A (en) 1995-03-01 1995-03-01 Methods and compositions for secretion of heterologous polypeptides
PCT/US1996/002858 WO1996027016A1 (en) 1995-03-01 1996-02-27 Methods and compositions for secretion of heterologous polypeptides

Publications (1)

Publication Number Publication Date
DK0815246T3 true DK0815246T3 (da) 2007-08-06

Family

ID=23576066

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96906659T DK0815246T3 (da) 1995-03-01 1996-02-27 Fremgangsmåder og sammensætninger til sekretion af heterologe polypeptider

Country Status (18)

Country Link
US (1) US5840523A (de)
EP (1) EP0815246B1 (de)
JP (1) JP3375970B2 (de)
CN (1) CN1154736C (de)
AT (1) ATE358181T1 (de)
AU (1) AU701476B2 (de)
BR (1) BR9607464B1 (de)
CA (1) CA2213813C (de)
DE (1) DE69636996T2 (de)
DK (1) DK0815246T3 (de)
ES (1) ES2285711T3 (de)
FI (1) FI120357B (de)
IL (1) IL117314A0 (de)
NO (1) NO324920B1 (de)
NZ (1) NZ303619A (de)
RU (1) RU2208639C2 (de)
WO (1) WO1996027016A1 (de)
ZA (1) ZA961688B (de)

Families Citing this family (744)

* Cited by examiner, † Cited by third party
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FI120357B (fi) 2009-09-30
JP3375970B2 (ja) 2003-02-10
AU701476B2 (en) 1999-01-28
US5840523A (en) 1998-11-24
FI973559A0 (fi) 1997-08-29
BR9607464A (pt) 1997-12-23
NZ303619A (en) 2000-02-28
FI973559A (fi) 1997-10-29
NO973985L (no) 1997-10-29
ZA961688B (en) 1997-09-01
IL117314A0 (en) 1996-06-18
NO324920B1 (no) 2008-01-07
CA2213813C (en) 2008-05-27
EP0815246A1 (de) 1998-01-07
AU4998496A (en) 1996-09-18
ES2285711T3 (es) 2007-11-16
ATE358181T1 (de) 2007-04-15
MX9706607A (es) 1997-11-29
NO973985D0 (no) 1997-08-29
DE69636996D1 (de) 2007-05-10
BR9607464B1 (pt) 2009-01-13
CN1154736C (zh) 2004-06-23
WO1996027016A1 (en) 1996-09-06
JPH10507368A (ja) 1998-07-21
EP0815246B1 (de) 2007-03-28
CN1180379A (zh) 1998-04-29
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