|
US2008526A
(en)
|
1932-11-03 |
1935-07-16 |
Wappler Frederick Charles |
Method and means for treating living tissue
|
|
US2588623A
(en)
|
1948-05-10 |
1952-03-11 |
Eliscu Frank |
Surgical instrument for intradermal injection of fluids
|
|
US3467096A
(en)
|
1966-04-12 |
1969-09-16 |
Ferrell S Horn |
Multiple hypodermic syringe arrangement
|
|
US3572336A
(en)
|
1968-04-30 |
1971-03-23 |
Daniel R Hershberg |
Syringe
|
|
BE757653A
(fr)
|
1969-10-21 |
1971-04-16 |
Ugine Kuhlmann |
Nouveaux medicaments derives d'acides nucleiques et procedes pour leur preparation
|
|
BE786542A
(fr)
|
1971-07-22 |
1973-01-22 |
Dow Corning |
Dispositif d'aspiration permettant d'obtenir des echantillons de cellules
|
|
US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
|
US4411657A
(en)
|
1980-05-19 |
1983-10-25 |
Anibal Galindo |
Hypodermic needle
|
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
US4474569A
(en)
|
1982-06-28 |
1984-10-02 |
Denver Surgical Developments, Inc. |
Antenatal shunt
|
|
JPS5927900A
(ja)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
固定化オリゴヌクレオチド
|
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
|
US4737462A
(en)
|
1982-10-19 |
1988-04-12 |
Cetus Corporation |
Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
|
|
FR2540122B1
(fr)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
|
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
|
US5118800A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
|
US4579849A
(en)
|
1984-04-06 |
1986-04-01 |
Merck & Co., Inc. |
N-alkylguanine acyclonucleosides as antiviral agents
|
|
US4957735A
(en)
|
1984-06-12 |
1990-09-18 |
The University Of Tennessee Research Corporation |
Target-sensitive immunoliposomes- preparation and characterization
|
|
FR2567892B1
(fr)
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
|
US4959314A
(en)
|
1984-11-09 |
1990-09-25 |
Cetus Corporation |
Cysteine-depleted muteins of biologically active proteins
|
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US5116943A
(en)
|
1985-01-18 |
1992-05-26 |
Cetus Corporation |
Oxidation-resistant muteins of Il-2 and other protein
|
|
CA1288073C
(en)
|
1985-03-07 |
1991-08-27 |
Paul G. Ahlquist |
Rna transformation vector
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
EP0204401A1
(en)
|
1985-04-09 |
1986-12-10 |
Biogen, Inc. |
Method of improving the yield of polypeptides produced in a host cell by stabilizing mRNA
|
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4695273A
(en)
|
1986-04-08 |
1987-09-22 |
I-Flow Corporation |
Multiple needle holder and subcutaneous multiple channel infusion port
|
|
US4879111A
(en)
|
1986-04-17 |
1989-11-07 |
Cetus Corporation |
Treatment of infections with lymphokines
|
|
JPS638396A
(ja)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
ポリ標識化オリゴヌクレオチド誘導体
|
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US6090591A
(en)
|
1987-07-31 |
2000-07-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
|
WO1989001050A1
(en)
|
1987-07-31 |
1989-02-09 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
|
DE3738460A1
(de)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
Modifizierte oligonukleotide
|
|
ATE92538T1
(de)
|
1988-01-21 |
1993-08-15 |
Genentech Inc |
Verstaerkung und nachweis von nukleinsaeuresequenzen.
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
JP2650159B2
(ja)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
核酸増幅方法
|
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
|
WO1989007947A1
(en)
|
1988-03-04 |
1989-09-08 |
Cancer Research Campaign Technology Limited |
Improvements relating to antigens
|
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
JPH02503867A
(ja)
|
1988-04-15 |
1990-11-15 |
プロテイン デザイン ラブズ インコーポレーテッド |
Ｉｌ‐２レセプター特異的キメラ抗体
|
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
|
US5021335A
(en)
|
1988-06-17 |
1991-06-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
|
US5759802A
(en)
|
1988-10-26 |
1998-06-02 |
Tonen Corporation |
Production of human serum alubumin A
|
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
DE69034168T3
(de)
|
1989-03-21 |
2013-04-11 |
Vical, Inc. |
Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
|
|
US6673776B1
(en)
|
1989-03-21 |
2004-01-06 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
|
|
US6214804B1
(en)
|
1989-03-21 |
2001-04-10 |
Vical Incorporated |
Induction of a protective immune response in a mammal by injecting a DNA sequence
|
|
US5693622A
(en)
|
1989-03-21 |
1997-12-02 |
Vical Incorporated |
Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
|
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
|
US5012818A
(en)
|
1989-05-04 |
1991-05-07 |
Joishy Suresh K |
Two in one bone marrow surgical needle
|
|
IE66597B1
(en)
|
1989-05-10 |
1996-01-24 |
Akzo Nv |
Method for the synthesis of ribonucleic acid (RNA)
|
|
US5240855A
(en)
|
1989-05-12 |
1993-08-31 |
Pioneer Hi-Bred International, Inc. |
Particle gun
|
|
US5332671A
(en)
|
1989-05-12 |
1994-07-26 |
Genetech, Inc. |
Production of vascular endothelial cell growth factor and DNA encoding same
|
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
|
US5545522A
(en)
|
1989-09-22 |
1996-08-13 |
Van Gelder; Russell N. |
Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
|
|
ATE190981T1
(de)
|
1989-10-24 |
2000-04-15 |
Isis Pharmaceuticals Inc |
2'-modifizierte nukleotide
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
NO904633L
(no)
|
1989-11-09 |
1991-05-10 |
Molecular Diagnostics Inc |
Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe.
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5215899A
(en)
|
1989-11-09 |
1993-06-01 |
Miles Inc. |
Nucleic acid amplification employing ligatable hairpin probe and transcription
|
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5697901A
(en)
|
1989-12-14 |
1997-12-16 |
Elof Eriksson |
Gene delivery by microneedle injection
|
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
AU7579991A
(en)
|
1990-02-20 |
1991-09-18 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
|
GB9009980D0
(en)
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
|
DE69032425T2
(de)
|
1990-05-11 |
1998-11-26 |
Microprobe Corp., Bothell, Wash. |
Teststreifen zum Eintauchen für Nukleinsäure-Hybridisierungsassays und Verfahren zur kovalenten Immobilisierung von Oligonucleotiden
|
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
|
JPH06500014A
(ja)
|
1990-07-25 |
1994-01-06 |
シンジーン，インコーポレイテッド |
多数の核酸相補体を生成させる環状伸長法
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
|
EP0556301B1
(en)
|
1990-11-08 |
2001-01-10 |
Hybridon, Inc. |
Incorporation of multiple reporter groups on synthetic oligonucleotides
|
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
US6100024A
(en)
|
1991-02-08 |
2000-08-08 |
Promega Corporation |
Methods and compositions for nucleic acid detection by target extension and probe amplification
|
|
EP1857554A1
(en)
|
1991-03-18 |
2007-11-21 |
New York University |
Monoclonal and chimeric antibodies specific for human tumor necrosis factor
|
|
US5426180A
(en)
|
1991-03-27 |
1995-06-20 |
Research Corporation Technologies, Inc. |
Methods of making single-stranded circular oligonucleotides
|
|
DE122009000019I1
(de)
|
1991-04-25 |
2009-07-16 |
Chugai Seiyaku K K 5 1 |
Rekombinierte humane antikörper gegen den humanen interleukin-6 rezeptor
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5169766A
(en)
|
1991-06-14 |
1992-12-08 |
Life Technologies, Inc. |
Amplification of nucleic acid molecules
|
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
|
US5199441A
(en)
|
1991-08-20 |
1993-04-06 |
Hogle Hugh H |
Fine needle aspiration biopsy apparatus and method
|
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
ES2103918T3
(es)
|
1991-10-17 |
1997-10-01 |
Ciba Geigy Ag |
Nucleosidos biciclicos, oligonucleotidos, procedimiento para su obtencion y productos intermedios.
|
|
US5298422A
(en)
|
1991-11-06 |
1994-03-29 |
Baylor College Of Medicine |
Myogenic vector systems
|
|
US5359044A
(en)
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
|
US5824307A
(en)
|
1991-12-23 |
1998-10-20 |
Medimmune, Inc. |
Human-murine chimeric antibodies against respiratory syncytial virus
|
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
|
JPH07503372A
(ja)
|
1992-01-23 |
1995-04-13 |
バイカル・インコーポレイテッド |
生体外遺伝子導入
|
|
FR2687679B1
(fr)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
Oligothionucleotides.
|
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
JP3368603B2
(ja)
|
1992-02-28 |
2003-01-20 |
オリンパス光学工業株式会社 |
遺伝子治療用処置具
|
|
DE69231123T2
(de)
|
1992-03-25 |
2001-02-15 |
Immunogen Inc |
Konjugaten von Zell-bindender Mittel und Derivaten von CC-1065
|
|
US6174666B1
(en)
|
1992-03-27 |
2001-01-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of eliminating inhibitory/instability regions from mRNA
|
|
US6132419A
(en)
|
1992-05-22 |
2000-10-17 |
Genetronics, Inc. |
Electroporetic gene and drug therapy
|
|
US5514545A
(en)
|
1992-06-11 |
1996-05-07 |
Trustees Of The University Of Pennsylvania |
Method for characterizing single cells based on RNA amplification for diagnostics and therapeutics
|
|
EP0577558A2
(de)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte
|
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
ATE152180T1
(de)
|
1992-07-31 |
1997-05-15 |
Behringwerke Ag |
Verfahren zur einführung von definierten sequenzen am 3' ende von polynukleotiden
|
|
US5273525A
(en)
|
1992-08-13 |
1993-12-28 |
Btx Inc. |
Injection and electroporation apparatus for drug and gene delivery
|
|
US5240885A
(en)
|
1992-09-21 |
1993-08-31 |
Corning Incorporated |
Rare earth-doped, stabilized cadmium halide glasses
|
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
WO1994009838A1
(en)
|
1992-11-04 |
1994-05-11 |
Denver Biomaterials, Inc. |
Apparatus for removal of pleural effusion fluid
|
|
EP1005870B1
(en)
|
1992-11-13 |
2009-01-21 |
Biogen Idec Inc. |
Therapeutic application of chimeric antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
|
CA2153692C
(en)
|
1993-01-12 |
2011-11-08 |
Roy R. Lobb |
Recombinant anti-vla4 antibody molecules
|
|
FR2703253B1
(fr)
|
1993-03-30 |
1995-06-23 |
Centre Nat Rech Scient |
Applicateur d'impulsions electriques pour traitement de tissus biologiques.
|
|
DE69404289T2
(de)
|
1993-03-30 |
1998-02-19 |
Sanofi Sa |
Acyclische nucleosid analoge und sie enthaltende oligonucleotidsequenzen
|
|
DE4311944A1
(de)
|
1993-04-10 |
1994-10-13 |
Degussa |
Umhüllte Natriumpercarbonatpartikel, Verfahren zu deren Herstellung und sie enthaltende Wasch-, Reinigungs- und Bleichmittelzusammensetzungen
|
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
|
US5773244A
(en)
|
1993-05-19 |
1998-06-30 |
Regents Of The University Of California |
Methods of making circular RNA
|
|
US6541498B2
(en)
|
1993-05-20 |
2003-04-01 |
Texas Biotechnology |
Benzenesulfonamides and the use thereof to modulate the activity of endothelin
|
|
US5851829A
(en)
|
1993-07-16 |
1998-12-22 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
|
US5672491A
(en)
|
1993-09-20 |
1997-09-30 |
The Leland Stanford Junior University |
Recombinant production of novel polyketides
|
|
US6432711B1
(en)
|
1993-11-03 |
2002-08-13 |
Diacrin, Inc. |
Embryonic stem cells capable of differentiating into desired cell lines
|
|
US6096503A
(en)
|
1993-11-12 |
2000-08-01 |
The Scripps Research Institute |
Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
|
|
US5446137B1
(en)
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
|
US7435802B2
(en)
|
1994-01-25 |
2008-10-14 |
Elan Pharaceuticals, Inc. |
Humanized anti-VLA4 immunoglobulins
|
|
US5840299A
(en)
|
1994-01-25 |
1998-11-24 |
Athena Neurosciences, Inc. |
Humanized antibodies against leukocyte adhesion molecule VLA-4
|
|
DE69533295T3
(de)
|
1994-02-16 |
2009-07-16 |
The Government Of The United States Of America, As Represented By The Secretary, The Department Of Health And Human Services |
Melanoma-assoziierte Antigene, Epitope davon und Impstoffe gegen Melanoma
|
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
IL112820A0
(en)
|
1994-03-07 |
1995-05-26 |
Merck & Co Inc |
Coordinate in vivo gene expression
|
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
WO1995025814A1
(en)
|
1994-03-18 |
1995-09-28 |
Lynx Therapeutics, Inc. |
Oligonucleotide n3'→p5' phosphoramidates: synthesis and compounds; hybridization and nuclease resistance properties
|
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US5457041A
(en)
|
1994-03-25 |
1995-10-10 |
Science Applications International Corporation |
Needle array and method of introducing biological substances into living cells using the needle array
|
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
|
US5464395A
(en)
|
1994-04-05 |
1995-11-07 |
Faxon; David P. |
Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
|
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
|
PT759993E
(pt)
|
1994-05-18 |
2007-08-10 |
Bayer Bioscience Gmbh |
''sequências de dna que codificam para enzimas capazes de facilitar a síntese de alfa-1,4-glucanos lineares em plantas, fungos e microrganismos''
|
|
AU2656295A
(en)
|
1994-06-02 |
1996-01-04 |
Chiron Corporation |
Nucleic acid immunization using a virus-based infection/transfection system
|
|
GB9412230D0
(en)
|
1994-06-17 |
1994-08-10 |
Celltech Ltd |
Interleukin-5 specific recombiant antibodies
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
|
IL114909A
(en)
|
1994-08-12 |
1999-10-28 |
Immunomedics Inc |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5641665A
(en)
|
1994-11-28 |
1997-06-24 |
Vical Incorporated |
Plasmids suitable for IL-2 expression
|
|
US5665545A
(en)
|
1994-11-28 |
1997-09-09 |
Akzo Nobel N.V. |
Terminal repeat amplification method
|
|
US5588960A
(en)
|
1994-12-01 |
1996-12-31 |
Vidamed, Inc. |
Transurethral needle delivery device with cystoscope and method for treatment of urinary incontinence
|
|
US5807718A
(en)
|
1994-12-02 |
1998-09-15 |
The Scripps Research Institute |
Enzymatic DNA molecules
|
|
US6057494A
(en)
|
1995-01-06 |
2000-05-02 |
Centrum Voor Plantenveredelings-En Reproduktieonderzoek |
DNA sequences encoding carbohydrate polymer synthesizing enzymes and method for producing transgenic plants
|
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5824497A
(en)
|
1995-02-10 |
1998-10-20 |
Mcmaster University |
High efficiency translation of mRNA molecules
|
|
EP0727187B1
(en)
|
1995-02-15 |
2003-08-06 |
Joseph Eldor |
Multiple hole spinal needle
|
|
US5707807A
(en)
|
1995-03-28 |
1998-01-13 |
Research Development Corporation Of Japan |
Molecular indexing for expressed gene analysis
|
|
US5869230A
(en)
|
1995-03-30 |
1999-02-09 |
Beth Israel Hospital Association |
Gene transfer into the kidney
|
|
US5986054A
(en)
|
1995-04-28 |
1999-11-16 |
The Hospital For Sick Children, Hsc Research And Development Limited Partnership |
Genetic sequences and proteins related to alzheimer's disease
|
|
FR2733762B1
(fr)
|
1995-05-02 |
1997-08-01 |
Genset Sa |
Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet
|
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
|
US6111095A
(en)
|
1995-06-07 |
2000-08-29 |
Merck & Co., Inc. |
Capped synthetic RNA, analogs, and aptamers
|
|
US5889136A
(en)
|
1995-06-09 |
1999-03-30 |
The Regents Of The University Of Colorado |
Orthoester protecting groups in RNA synthesis
|
|
US5713863A
(en)
|
1996-01-11 |
1998-02-03 |
Interventional Technologies Inc. |
Catheter with fluid medication injectors
|
|
US5766903A
(en)
|
1995-08-23 |
1998-06-16 |
University Technology Corporation |
Circular RNA and uses thereof
|
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
|
WO1997011085A1
(en)
|
1995-09-19 |
1997-03-27 |
University Of Massachusetts |
Inhibited biological degradation of oligodeoxynucleotides
|
|
US5830879A
(en)
|
1995-10-02 |
1998-11-03 |
St. Elizabeth's Medical Center Of Boston, Inc. |
Treatment of vascular injury using vascular endothelial growth factor
|
|
US6265387B1
(en)
|
1995-10-11 |
2001-07-24 |
Mirus, Inc. |
Process of delivering naked DNA into a hepatocyte via bile duct
|
|
EP0771873A3
(en)
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
|
CU22584A1
(es)
|
1995-11-17 |
1999-11-03 |
Centro Inmunologia Molecular |
Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis
|
|
US6090382A
(en)
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
|
US5962271A
(en)
|
1996-01-03 |
1999-10-05 |
Cloutech Laboratories, Inc. |
Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
|
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
US6261584B1
(en)
|
1996-02-02 |
2001-07-17 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
|
US6395292B2
(en)
|
1996-02-02 |
2002-05-28 |
Alza Corporation |
Sustained delivery of an active agent using an implantable system
|
|
AU1874397A
(en)
|
1996-02-16 |
1997-09-02 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
|
US6534312B1
(en)
|
1996-02-22 |
2003-03-18 |
Merck & Co., Inc. |
Vaccines comprising synthetic genes
|
|
US6090391A
(en)
|
1996-02-23 |
2000-07-18 |
Aviron |
Recombinant tryptophan mutants of influenza
|
|
US6300487B1
(en)
|
1996-03-19 |
2001-10-09 |
Cell Therapuetics, Inc. |
Mammalian lysophosphatidic acid acyltransferase
|
|
TW517061B
(en)
|
1996-03-29 |
2003-01-11 |
Pharmacia & Amp Upjohn Ab |
Modified/chimeric superantigens and their use
|
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
|
US20030073908A1
(en)
|
1996-04-26 |
2003-04-17 |
2000 Injectx, Inc. |
Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells
|
|
US5712127A
(en)
|
1996-04-29 |
1998-01-27 |
Genescape Inc. |
Subtractive amplification
|
|
US5853719A
(en)
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
|
US6300484B1
(en)
|
1996-06-05 |
2001-10-09 |
Chiron Corporation |
DNA encoding DP. 75 and a process for its use
|
|
US7329741B2
(en)
|
1996-06-05 |
2008-02-12 |
Chiron Corporation |
Polynucleotides that hybridize to DP-75 and their use
|
|
JP2000516445A
(ja)
|
1996-06-21 |
2000-12-12 |
メルク エンド カンパニー インコーポレーテッド |
合成遺伝子を含むワクチン
|
|
JP2002515786A
(ja)
|
1996-06-28 |
2002-05-28 |
ソントラ メディカル，エル．ピー． |
経皮輸送の超音波増強
|
|
US5939262A
(en)
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
|
US5677124A
(en)
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
|
US7288266B2
(en)
|
1996-08-19 |
2007-10-30 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
|
US5849546A
(en)
|
1996-09-13 |
1998-12-15 |
Epicentre Technologies Corporation |
Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
EP0932678B2
(en)
|
1996-09-24 |
2010-03-10 |
Genentech, Inc. |
A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
ES2241042T3
(es)
|
1996-10-11 |
2005-10-16 |
The Regents Of The University Of California |
Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
|
|
EP0839912A1
(en)
|
1996-10-30 |
1998-05-06 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
|
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
|
US5980887A
(en)
|
1996-11-08 |
1999-11-09 |
St. Elizabeth's Medical Center Of Boston |
Methods for enhancing angiogenesis with endothelial progenitor cells
|
|
US5759179A
(en)
|
1996-12-31 |
1998-06-02 |
Johnson & Johnson Medical, Inc. |
Needle and valve assembly for use with a catheter
|
|
CA2278786C
(en)
|
1997-01-21 |
2010-07-20 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
|
DE69836206T2
(de)
|
1997-02-07 |
2007-08-23 |
Merck & Co., Inc. |
Synthetische hiv gag gene
|
|
US6696291B2
(en)
|
1997-02-07 |
2004-02-24 |
Merck & Co., Inc. |
Synthetic HIV gag genes
|
|
US6251665B1
(en)
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
|
JP3756313B2
(ja)
|
1997-03-07 |
2006-03-15 |
武 今西 |
新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
|
US5914269A
(en)
|
1997-04-04 |
1999-06-22 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide inhibition of epidermal growth factor receptor expression
|
|
AU6972798A
(en)
|
1997-04-18 |
1998-11-13 |
University Of Medicine And Dentistry Of New Jersey |
Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog
|
|
US5958688A
(en)
|
1997-04-28 |
1999-09-28 |
The Trustees Of The University Of Pennsylvania |
Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US5989911A
(en)
|
1997-05-09 |
1999-11-23 |
University Of Massachusetts |
Site-specific synthesis of pseudouridine in RNA
|
|
US6761726B1
(en)
|
1998-05-15 |
2004-07-13 |
Pyng Medical Corp. |
Method and apparatus for the intraosseous introduction of a device such as an infusion tube
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
US6124091A
(en)
|
1997-05-30 |
2000-09-26 |
Research Corporation Technologies, Inc. |
Cell growth-controlling oligonucleotides
|
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
ATE432348T1
(de)
|
1997-06-06 |
2009-06-15 |
Univ California |
Inhibitoren von immunstimulatorischen dna sequenz aktivität
|
|
FI105309B
(fi)
|
1997-06-24 |
2000-07-14 |
Nokia Mobile Phones Ltd |
Matkaviestinjärjestelmät
|
|
AU731909B2
(en)
|
1997-07-01 |
2001-04-05 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for the delivery of oligonucleotides via the alimentary canal
|
|
US5994511A
(en)
|
1997-07-02 |
1999-11-30 |
Genentech, Inc. |
Anti-IgE antibodies and methods of improving polypeptides
|
|
BR9815493A
(pt)
|
1997-07-21 |
2000-10-31 |
Pharmacia & Upjohn Ab |
Citólise dirigida de células-alvo, agentes e composições que causam citólise, e compostos que podem ser usados para produzir os agentes
|
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
|
JP2001511462A
(ja)
|
1997-07-31 |
2001-08-14 |
セント エリザベス メディカル センター オブ ボストン インク． |
移植片処置法
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US7151172B1
(en)
|
1997-09-18 |
2006-12-19 |
The Trustees Of The University Of Pennsylvania |
Attenuated vif DNA immunization cassettes for genetic vaccines
|
|
AU9319398A
(en)
|
1997-09-19 |
1999-04-05 |
Sequitur, Inc. |
Sense mrna therapy
|
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
EP1021548A1
(en)
|
1997-10-07 |
2000-07-26 |
University Of Maryland Biotechnology Institute |
Method for introducing and expressing rna in animal cells
|
|
AP1219A
(en)
|
1997-10-20 |
2003-10-22 |
Gtc Biotherapeutics Inc |
Novel modified MSP-1 nucleic acid sequences and methods for increasing mRNA levels and protein expression in cell systems.
|
|
US6019747A
(en)
|
1997-10-21 |
2000-02-01 |
I-Flow Corporation |
Spring-actuated infusion syringe
|
|
WO1999022009A1
(en)
|
1997-10-24 |
1999-05-06 |
Megabios Corporation |
Methods for preparing polynucleotide transfection complexes
|
|
US6077251A
(en)
|
1997-10-30 |
2000-06-20 |
Ting; Windsor |
Medicinal agent administration system
|
|
CA2309535A1
(en)
|
1997-11-12 |
1999-05-20 |
Brigham And Women's Hospital, Inc. |
The translation enhancer element of the human amyloid precursor protein gene
|
|
US6548633B1
(en)
|
1998-12-22 |
2003-04-15 |
Genset, S.A. |
Complementary DNA's encoding proteins with signal peptides
|
|
CA2309766C
(en)
|
1997-11-20 |
2008-09-30 |
Vical Incorporated |
Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
|
|
US7655777B2
(en)
|
1997-11-24 |
2010-02-02 |
Monsanto Technology Llc |
Nucleic acid molecules associated with the tocopherol pathway
|
|
WO1999029758A1
(en)
|
1997-12-12 |
1999-06-17 |
Samyang Corporation |
Positively-charged poly[alpha-(omega-aminoalkyl)glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
|
JP2002500010A
(ja)
|
1997-12-23 |
2002-01-08 |
カイロン コーポレイション |
ヒト遺伝子および遺伝子発現産物ｉ
|
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
US6383811B2
(en)
|
1997-12-30 |
2002-05-07 |
Mirus Corporation |
Polyampholytes for delivering polyions to a cell
|
|
EP2138191A1
(en)
|
1998-01-05 |
2009-12-30 |
University Of Washington |
Enhanced transport using membrane disruptive agents
|
|
CA2317777C
(en)
|
1998-01-08 |
2005-05-03 |
Sontra Medical, Inc. |
Sonophoretic enhanced transdermal transport
|
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
|
US6365346B1
(en)
|
1998-02-18 |
2002-04-02 |
Dade Behring Inc. |
Quantitative determination of nucleic acid amplification products
|
|
US5955310A
(en)
|
1998-02-26 |
1999-09-21 |
Novo Nordisk Biotech, Inc. |
Methods for producing a polypeptide in a bacillus cell
|
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
|
US6429301B1
(en)
|
1998-04-17 |
2002-08-06 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
|
GB9808327D0
(en)
|
1998-04-20 |
1998-06-17 |
Chiron Spa |
Antidiotypic compounds
|
|
WO1999054455A1
(fr)
|
1998-04-23 |
1999-10-28 |
Takara Shuzo Co., Ltd. |
Procede de synthese de l'adn
|
|
US6395253B2
(en)
|
1998-04-23 |
2002-05-28 |
The Regents Of The University Of Michigan |
Microspheres containing condensed polyanionic bioactive agents and methods for their production
|
|
US20020064517A1
(en)
|
1998-04-30 |
2002-05-30 |
Stewart A. Cederholm-Williams |
Fibrin sealant as a transfection/transformation vehicle for gene therapy
|
|
US20090208418A1
(en)
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
|
AU4193199A
(en)
|
1998-05-20 |
1999-12-06 |
Expression Genetics, Inc. |
A hepatocyte targeting polyethylene glyco-grafted poly-l-lysine polymeric gene carrier
|
|
US6503231B1
(en)
|
1998-06-10 |
2003-01-07 |
Georgia Tech Research Corporation |
Microneedle device for transport of molecules across tissue
|
|
US7091192B1
(en)
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
|
CN1313873A
(zh)
|
1998-07-13 |
2001-09-19 |
表达遗传学公司 |
作为可溶性,生物可降解基因送递载体的聚－l－赖氨酸的聚酯类似物
|
|
US6222030B1
(en)
|
1998-08-03 |
2001-04-24 |
Agilent Technologies, Inc. |
Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
|
|
HK1041221A1
(zh)
|
1998-08-11 |
2002-07-05 |
Idec药物公司 |
包括施用抗-cd20抗体的b-细胞淋巴瘤联合疗法
|
|
GB9817662D0
(en)
|
1998-08-13 |
1998-10-07 |
Crocker Peter J |
Substance delivery
|
|
US20090148906A1
(en)
|
1998-09-29 |
2009-06-11 |
Shire Human Genetic Therapies, Inc. A Delaware Corporation |
Optimized messenger rna
|
|
US6924365B1
(en)
|
1998-09-29 |
2005-08-02 |
Transkaryotic Therapies, Inc. |
Optimized messenger RNA
|
|
WO2000026226A1
(en)
|
1998-11-03 |
2000-05-11 |
Yale University |
Multidomain polynucleotide molecular sensors
|
|
ES2338287T3
(es)
|
1998-11-09 |
2010-05-05 |
Biogen Idec Inc. |
Tratamiento de anticuerpos anti-cd20 de pacientes que reciben trasplantes de injertos de medula osea o celulas madre de sangre periferica.
|
|
EP2289543A1
(en)
|
1998-11-09 |
2011-03-02 |
Biogen Idec Inc. |
Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-cd20 antibody
|
|
AU2023400A
(en)
|
1998-11-12 |
2000-05-29 |
Children's Medical Center Corporation |
Compositions and methods for inhibiting angiogenesis using trna and fragments thereof
|
|
US6210931B1
(en)
|
1998-11-30 |
2001-04-03 |
The United States Of America As Represented By The Secretary Of Agriculture |
Ribozyme-mediated synthesis of circular RNA
|
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
CA2356542A1
(en)
|
1998-12-23 |
2000-07-06 |
Human Genome Sciences, Inc. |
Peptidoglycan recognition proteins
|
|
US6255476B1
(en)
|
1999-02-22 |
2001-07-03 |
Pe Corporation (Ny) |
Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
|
|
EP1155124A2
(en)
|
1999-02-22 |
2001-11-21 |
European Molecular Biology Laboratory |
In vitro translation system
|
|
US7629311B2
(en)
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
|
EP1574210B1
(en)
|
1999-02-26 |
2016-04-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microemulsions with adsorbed macromolecules
|
|
ES2288846T3
(es)
|
1999-03-01 |
2008-02-01 |
Cytyc Corporation |
Aparato, procedimientos y kits para suministro simultaneo de una sustancia a multiples conductos galactoforos mamarios.
|
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
|
CA2369119A1
(en)
|
1999-03-29 |
2000-05-25 |
Statens Serum Institut |
Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope
|
|
CN1311005C
(zh)
|
1999-04-09 |
2007-04-18 |
迪纳尔生物技术公司 |
用于制备单分散聚合物颗粒的方法
|
|
CN102180924A
(zh)
|
1999-05-04 |
2011-09-14 |
桑塔里斯制药公司 |
L-核糖-lna类似物
|
|
US8663692B1
(en)
|
1999-05-07 |
2014-03-04 |
Pharmasol Gmbh |
Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
|
|
AU777970C
(en)
|
1999-05-07 |
2006-08-17 |
F. Hoffman-La Roche Ag |
Treatment of autoimmune diseases with antagonists which bind to B cell surface markers
|
|
US7171264B1
(en)
|
1999-05-10 |
2007-01-30 |
Genetronics, Inc. |
Intradermal delivery of active agents by needle-free injection and electroporation
|
|
US6346382B1
(en)
|
1999-06-01 |
2002-02-12 |
Vanderbilt University |
Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
|
|
WO2000075356A1
(en)
|
1999-06-04 |
2000-12-14 |
Lin Shi Lung |
Rna polymerase chain reaction
|
|
US6611707B1
(en)
|
1999-06-04 |
2003-08-26 |
Georgia Tech Research Corporation |
Microneedle drug delivery device
|
|
US6743211B1
(en)
|
1999-11-23 |
2004-06-01 |
Georgia Tech Research Corporation |
Devices and methods for enhanced microneedle penetration of biological barriers
|
|
US6303573B1
(en)
|
1999-06-07 |
2001-10-16 |
The Burnham Institute |
Heart homing peptides and methods of using same
|
|
NZ515957A
(en)
|
1999-06-08 |
2003-08-29 |
Aventis Pasteur |
Immunostimulant oligonucleotide
|
|
HK1046635B
(en)
|
1999-06-09 |
2009-10-09 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
IL147179A0
(en)
|
1999-06-30 |
2002-08-14 |
Advanced Cell Tech Inc |
Cytoplasmic transfer to de-differentiate recipient cells
|
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
|
AU783681B2
(en)
|
1999-07-09 |
2005-11-24 |
Wyeth |
Methods and compositions for preventing the formation of aberrant RNA during transcription of a plasmid sequence
|
|
CA2311201A1
(en)
|
1999-08-05 |
2001-02-05 |
Genset S.A. |
Ests and encoded human proteins
|
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
WO2001014424A2
(en)
|
1999-08-24 |
2001-03-01 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
US20050112141A1
(en)
|
2000-08-30 |
2005-05-26 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
|
US6551338B1
(en)
|
1999-09-01 |
2003-04-22 |
Mcgill University |
Method and device for myogenesis and angiogenesis of the heart
|
|
US20040106567A1
(en)
|
1999-09-07 |
2004-06-03 |
Hagstrom James E. |
Intravascular delivery of non-viral nucleic acid
|
|
EP1619254B1
(en)
|
1999-09-09 |
2010-12-22 |
CureVac GmbH |
Transfer of mRNA using polycationic compounds
|
|
WO2001021810A1
(en)
|
1999-09-17 |
2001-03-29 |
Aventis Pasteur Limited |
Chlamydia antigens and corresponding dna fragments and uses thereof
|
|
US6623457B1
(en)
|
1999-09-22 |
2003-09-23 |
Becton, Dickinson And Company |
Method and apparatus for the transdermal administration of a substance
|
|
WO2002064799A2
(en)
|
1999-09-28 |
2002-08-22 |
Transkaryotic Therapies, Inc. |
Optimized messenger rna
|
|
AU7863200A
(en)
|
1999-10-06 |
2001-05-10 |
Quark Biotech, Inc. |
Method for enrichment of natural antisense messenger rna
|
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
|
US6613026B1
(en)
|
1999-12-08 |
2003-09-02 |
Scimed Life Systems, Inc. |
Lateral needle-less injection apparatus and method
|
|
US6277974B1
(en)
|
1999-12-14 |
2001-08-21 |
Cogent Neuroscience, Inc. |
Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
|
|
US6245929B1
(en)
|
1999-12-20 |
2001-06-12 |
General Electric Company |
Catalyst composition and method for producing diaryl carbonates, using bisphosphines
|
|
ES2230173T3
(es)
|
1999-12-22 |
2005-05-01 |
Basell Poliolefine Italia S.P.A. |
Sistema catalizador para la polimerizacion de alfa olefinas el cual contiene un compuesto aromatico de silano.
|
|
SE515932C2
(sv)
|
1999-12-23 |
2001-10-29 |
Prostalund Operations Ab |
Sätt och anordning vid behandling av prostata
|
|
WO2001051092A2
(en)
|
2000-01-07 |
2001-07-19 |
University Of Washington |
Enhanced transport of agents using membrane disruptive agents
|
|
AU2001232485A1
(en)
|
2000-01-13 |
2001-07-24 |
Amsterdam Support Diagnostics B.V. |
A universal nucleic acid amplification system for nucleic acids in a sample
|
|
US7468275B2
(en)
|
2000-01-28 |
2008-12-23 |
The Scripps Research Institute |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
WO2001055369A1
(en)
|
2000-01-28 |
2001-08-02 |
The Scripps Research Institute |
Synthetic internal ribosome entry sites and methods of identifying same
|
|
US6552006B2
(en)
|
2000-01-31 |
2003-04-22 |
The Regents Of The University Of California |
Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen
|
|
CA2395811A1
(en)
|
2000-01-31 |
2001-08-02 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
|
US6602498B2
(en)
|
2000-02-22 |
2003-08-05 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
|
SI1257584T2
(sl)
|
2000-02-24 |
2013-07-31 |
Washington University St. Louis |
Humanizirana protitelesa, ki veĹľejo amiloidni peptid beta
|
|
WO2001066149A2
(en)
|
2000-03-03 |
2001-09-13 |
Valentis, Inc. |
Nucleic acid formulations for gene delivery and methods of use
|
|
US20020081597A1
(en)
|
2000-03-31 |
2002-06-27 |
Genentech, Inc. |
Compositions and methods for detecting and quantifying gene expression
|
|
KR20020091170A
(ko)
|
2000-03-31 |
2002-12-05 |
아이덱 파마슈티칼즈 코포레이션 |
Ｂ 세포 림프종의 치료를 위한 항-사이토카인 항체 또는길항제 및 항-ｃｄ２０의 조합된 사용
|
|
US6565572B2
(en)
|
2000-04-10 |
2003-05-20 |
Sdgi Holdings, Inc. |
Fenestrated surgical screw and method
|
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
|
AU2001266557A1
(en)
|
2000-04-12 |
2001-10-23 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
US20010046496A1
(en)
|
2000-04-14 |
2001-11-29 |
Brettman Lee R. |
Method of administering an antibody
|
|
US6468247B1
(en)
|
2000-04-21 |
2002-10-22 |
Mark Zamoyski |
Perfusion device for localized drug delivery
|
|
US6375972B1
(en)
|
2000-04-26 |
2002-04-23 |
Control Delivery Systems, Inc. |
Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
|
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
|
WO2001092523A2
(en)
|
2000-05-30 |
2001-12-06 |
Curagen Corporation |
Human polynucleotides and polypeptides encoded thereby
|
|
US6537242B1
(en)
|
2000-06-06 |
2003-03-25 |
Becton, Dickinson And Company |
Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
|
|
JP2004530629A
(ja)
|
2000-06-07 |
2004-10-07 |
バイオシネクサス インコーポレーテッド |
免疫刺激ｒｎａ／ｄｎａハイブリッド分子
|
|
US6607513B1
(en)
|
2000-06-08 |
2003-08-19 |
Becton, Dickinson And Company |
Device for withdrawing or administering a substance and method of manufacturing a device
|
|
US6664066B2
(en)
|
2000-06-23 |
2003-12-16 |
Wyeth Holdings Corporation |
Modified Morbillivirus V proteins
|
|
US20050181033A1
(en)
|
2000-06-29 |
2005-08-18 |
Dekker John P.Iii |
Method for delivering interferons to the intradermal compartment
|
|
WO2002002606A2
(en)
|
2000-07-03 |
2002-01-10 |
Chiron S.P.A. |
Immunisation against chlamydia pneumoniae
|
|
US6440096B1
(en)
|
2000-07-14 |
2002-08-27 |
Becton, Dickinson And Co. |
Microdevice and method of manufacturing a microdevice
|
|
WO2002008435A1
(en)
|
2000-07-21 |
2002-01-31 |
Glaxo Group Limited |
Codon-optimized papilloma virus sequences
|
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
|
WO2002024873A1
(en)
|
2000-09-20 |
2002-03-28 |
Christopher Ralph Franks |
Stem cell therapy
|
|
AU2002211490A1
(en)
|
2000-10-04 |
2002-04-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of using capsid protein from flaviviruses and pestiviruses
|
|
JP4413493B2
(ja)
|
2000-10-04 |
2010-02-10 |
サンタリス ファーマ アー／エス |
プリンｌｎａ類似体の改善された合成方法
|
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
US7202226B2
(en)
|
2000-10-23 |
2007-04-10 |
Detroit R & D |
Augmentation of wound healing by elF-4E mRNA and EGF mRNA
|
|
US20030077604A1
(en)
|
2000-10-27 |
2003-04-24 |
Yongming Sun |
Compositions and methods relating to breast specific genes and proteins
|
|
US20020132788A1
(en)
|
2000-11-06 |
2002-09-19 |
David Lewis |
Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo
|
|
AU2002226930A1
(en)
|
2000-11-17 |
2002-05-27 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point
|
|
EP2336368A1
(en)
|
2000-12-07 |
2011-06-22 |
Novartis Vaccines and Diagnostics, Inc. |
Endogenous retroviruses up-regulated in prostate cancer
|
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
|
US20020130430A1
(en)
|
2000-12-29 |
2002-09-19 |
Castor Trevor Percival |
Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products
|
|
US7628780B2
(en)
|
2001-01-13 |
2009-12-08 |
Medtronic, Inc. |
Devices and methods for interstitial injection of biologic agents into tissue
|
|
EP1224943A1
(en)
|
2001-01-19 |
2002-07-24 |
Crucell Holland B.V. |
Fibronectin as a tumor marker detected by phage antibodies
|
|
WO2002057302A2
(en)
|
2001-01-19 |
2002-07-25 |
Vironovative B.V. |
A virus causing respiratory tract illness in susceptible mammals
|
|
US20040110191A1
(en)
|
2001-01-31 |
2004-06-10 |
Winkler Matthew M. |
Comparative analysis of nucleic acids using population tagging
|
|
CA2437737A1
(en)
|
2001-02-14 |
2002-08-22 |
Stephen D. Ginsberg |
Methods and compositions of amplifying rna
|
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
|
DE10109897A1
(de)
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
|
US7232425B2
(en)
|
2001-03-02 |
2007-06-19 |
Sorenson Development, Inc. |
Apparatus and method for specific interstitial or subcutaneous diffusion and dispersion of medication
|
|
AU2002242474B2
(en)
|
2001-03-09 |
2004-05-20 |
Gene Stream Pty Ltd |
Novel expression vectors
|
|
JP2002262882A
(ja)
|
2001-03-12 |
2002-09-17 |
Nisshinbo Ind Inc |
Ｒｎａの増幅法
|
|
FR2822164B1
(fr)
|
2001-03-19 |
2004-06-18 |
Centre Nat Rech Scient |
Polypeptides derives des arn polymerases, et leurs utilisations
|
|
US6520949B2
(en)
|
2001-04-02 |
2003-02-18 |
Martin St. Germain |
Method and apparatus for administering fluid to animals subcutaneously
|
|
US6625486B2
(en)
|
2001-04-11 |
2003-09-23 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for intracellular delivery of an agent
|
|
DE10119005A1
(de)
|
2001-04-18 |
2002-10-24 |
Roche Diagnostics Gmbh |
Verfahren zur Proteinexpression ausgehend von stabilisierter linearer kurzer DNA in zellfreien in vitro-Transkription/Translations-Systemen mit Exonuklease-haltigen Lysaten oder in einem zellulären System enthaltend Exonukleasen
|
|
US20030171253A1
(en)
|
2001-04-19 |
2003-09-11 |
Averil Ma |
Methods and compositions relating to modulation of A20
|
|
DE10291734D2
(de)
|
2001-04-23 |
2004-05-27 |
Lorbach Elke |
Pufferlösung für die Elektroporation und Verfahren umfassend die Verwendung derselben
|
|
US7560424B2
(en)
|
2001-04-30 |
2009-07-14 |
Zystor Therapeutics, Inc. |
Targeted therapeutic proteins
|
|
US6777187B2
(en)
|
2001-05-02 |
2004-08-17 |
Rubicon Genomics, Inc. |
Genome walking by selective amplification of nick-translate DNA library and amplification from complex mixtures of templates
|
|
AU2002308623A1
(en)
|
2001-05-08 |
2002-11-18 |
Magnatech International, L.P. |
Electronic length control wire pay-off system and method
|
|
US20050137155A1
(en)
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
|
US8137911B2
(en)
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
|
AU2002314855B2
(en)
|
2001-05-30 |
2007-08-09 |
Board Of Trustees Of The Leland Stanford, Jr., University |
Delivery system for nucleic acids
|
|
DE50214379D1
(de)
|
2001-06-05 |
2010-05-27 |
Curevac Gmbh |
Stabilisierte mRNA mit erhöhtem G/C-Gehalt für die Gentherapie
|
|
EP1402035A2
(en)
|
2001-06-18 |
2004-03-31 |
Novartis AG |
G-protein coupled receptors and dna sequences thereof
|
|
US7547551B2
(en)
|
2001-06-21 |
2009-06-16 |
University Of Antwerp. |
Transfection of eukaryontic cells with linear polynucleotides by electroporation
|
|
US7785610B2
(en)
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
|
JP2005503137A
(ja)
|
2001-06-26 |
2005-02-03 |
ノバルティス アクチエンゲゼルシャフト |
Ｇタンパク質共役レセプターおよびそのｄｎａ配列
|
|
SE0102327D0
(sv)
|
2001-06-28 |
2001-06-28 |
Active Biotech Ab |
A novel engineered superantigen for human therapy
|
|
CA2451816A1
(en)
|
2001-06-29 |
2003-01-09 |
Becton, Dickinson And Company |
Intradermal delivery of vaccines and gene therapeutic agents via microcannula
|
|
US20040236092A1
(en)
|
2001-07-13 |
2004-11-25 |
Roman Dziarski |
Peptidologlycan recognition protein encoding nucleic acids and methods of use thereof
|
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
|
ATE481497T1
(de)
|
2001-08-01 |
2010-10-15 |
Univ Utah |
Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
|
|
JP2005502344A
(ja)
|
2001-08-27 |
2005-01-27 |
ノバルティス アクチエンゲゼルシャフト |
新規ｇタンパク質共役受容体およびそのｄｎａ配列
|
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
|
WO2003029459A2
(en)
|
2001-09-28 |
2003-04-10 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Micro-rna molecules
|
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
|
DE10148886A1
(de)
|
2001-10-04 |
2003-04-30 |
Avontec Gmbh |
Inhibition von STAT-1
|
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
US7429258B2
(en)
|
2001-10-26 |
2008-09-30 |
Massachusetts Institute Of Technology |
Microneedle transport device
|
|
US7384739B2
(en)
|
2001-11-14 |
2008-06-10 |
Toyo Boseki Kabushiki Kaisha |
Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
|
|
US20030138419A1
(en)
|
2001-11-16 |
2003-07-24 |
The University Of Tennessee Research Corporation |
Recombinant antibody fusion proteins and methods for detection of apoptotic cells
|
|
EP1454145A2
(en)
|
2001-11-29 |
2004-09-08 |
Novartis AG |
Method for the assessment and prognosis of sarcoidosis
|
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
|
JP4822490B2
(ja)
|
2001-12-07 |
2011-11-24 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
腫瘍形成形質転換に関連する内因性レトロウイルスポリペプチド
|
|
US20060275747A1
(en)
|
2001-12-07 |
2006-12-07 |
Hardy Stephen F |
Endogenous retrovirus up-regulated in prostate cancer
|
|
JP4646315B2
(ja)
|
2001-12-07 |
2011-03-09 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
前立腺癌においてアップレギュレートされた内因性レトロウイルス
|
|
US20050107589A1
(en)
|
2001-12-17 |
2005-05-19 |
Gung-Wei Chirn |
Novel g-protein coupled receptors and dna sequences thereof
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
DE60237475D1
(de)
|
2001-12-21 |
2010-10-07 |
Alcon Inc |
Verwendung von synthetischen anorganischen nanoteilchen als träger für augenmedikamente
|
|
AU2003235707A1
(en)
|
2002-01-18 |
2003-07-30 |
Curevac Gmbh |
Immunogenic preparations and vaccines on the basis of mrna
|
|
CA2474709A1
(en)
|
2002-02-04 |
2003-08-14 |
Biomira, Inc. |
Immunostimulatory, covalently lipidated oligonucleotides
|
|
WO2003066662A2
(en)
|
2002-02-05 |
2003-08-14 |
Genentech, Inc. |
Protein purification
|
|
FR2835749B1
(fr)
|
2002-02-08 |
2006-04-14 |
Inst Nat Sante Rech Med |
Composition pharmaceutique ameliorant le transfert de gene in vivo
|
|
DE10207178A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Komponenten für die Herstellung amphoterer Liposomen
|
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
US7354742B2
(en)
|
2002-02-22 |
2008-04-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method for generating amplified RNA
|
|
NZ535690A
(en)
|
2002-02-26 |
2009-04-30 |
Maxygen Inc |
Novel flavivirus antigens
|
|
DK1487856T3
(da)
|
2002-03-04 |
2010-10-18 |
Imclone Llc |
KDR-specifikke humane antistoffer og deres anvendelse
|
|
AU2003221497A1
(en)
|
2002-03-13 |
2003-09-22 |
Novartis Ag |
Pharmaceutical microparticles
|
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
|
EP1499187B1
(en)
|
2002-04-04 |
2015-06-17 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
|
EP1497327A2
(en)
|
2002-04-17 |
2005-01-19 |
Novartis AG |
Method for the identification of inhibitors of the binding of are-containing mrna and an hur protein
|
|
GB0209539D0
(en)
|
2002-04-26 |
2002-06-05 |
Avecia Ltd |
Monomer Polymer and process
|
|
EP1361277A1
(en)
|
2002-04-30 |
2003-11-12 |
Centre National De La Recherche Scientifique (Cnrs) |
Optimization of transgene expression in mammalian cells
|
|
HUE057124T2
(hu)
|
2002-05-02 |
2022-04-28 |
Wyeth Holdings Llc |
Calicheamicin származék - hordozó konjugátumok
|
|
BR0311443A
(pt)
|
2002-05-06 |
2005-03-22 |
Becton Dickinson Co |
Método e dispositivo para controlar farmacocinética de droga
|
|
JP2005538945A
(ja)
|
2002-05-08 |
2005-12-22 |
ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア |
心不整脈を線維芽細胞で治療するためのシステム及び方法
|
|
US20040018525A1
(en)
|
2002-05-21 |
2004-01-29 |
Bayer Aktiengesellschaft |
Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
|
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
|
DE10224200C1
(de)
|
2002-05-31 |
2003-08-21 |
Artus Ges Fuer Molekularbiolog |
Vermehrung von Ribonukleinsäuren
|
|
WO2003101401A2
(en)
|
2002-06-03 |
2003-12-11 |
Chiron Corporation |
Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
|
|
SE0201907D0
(sv)
|
2002-06-19 |
2002-06-19 |
Atos Medical Ab |
Plaster for tracheostoma valves
|
|
ATE485031T1
(de)
|
2002-06-28 |
2010-11-15 |
Protiva Biotherapeutics Inc |
Verfahren und vorrichtung zur herstellung von liposomen
|
|
MXPA05000063A
(es)
|
2002-07-01 |
2005-04-08 |
Kenneth S Warren Inst Inc |
Citocinas recombinantes protectoras de tejido y acidos nucleicos que las codifican para la proteccion, restauracion y mejora de celulas, tejidos y organos respondedores.
|
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
|
GB0215509D0
(en)
|
2002-07-04 |
2002-08-14 |
Novartis Ag |
Marker genes
|
|
US20040009180A1
(en)
|
2002-07-11 |
2004-01-15 |
Allergan, Inc. |
Transdermal botulinum toxin compositions
|
|
US7316925B2
(en)
|
2002-07-16 |
2008-01-08 |
Vgx Pharmaceuticals, Inc. |
Codon optimized synthetic plasmids
|
|
AU2003252136A1
(en)
|
2002-07-24 |
2004-02-09 |
Ptc Therapeutics, Inc. |
METHODS FOR IDENTIFYING SMALL MOLEDULES THAT MODULATE PREMATURE TRANSLATION TERMINATION AND NONSENSE MEDIATED mRNA DECAY
|
|
EP1393745A1
(en)
|
2002-07-29 |
2004-03-03 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends
|
|
US6653468B1
(en)
|
2002-07-31 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Universal support media for synthesis of oligomeric compounds
|
|
EP1386925A1
(en)
|
2002-07-31 |
2004-02-04 |
Girindus AG |
Method for preparing oligonucleotides
|
|
CA2492639C
(en)
|
2002-08-01 |
2013-06-18 |
Abbott Laboratories Vascular Enterprises, Limited |
Apparatus for sealing a puncture by causing a reduction in the circumference of the puncture
|
|
EP1873180B1
(en)
|
2002-08-14 |
2014-05-07 |
Novartis AG |
Ophthalmic device made from a radiation-curable prepolymer
|
|
CA2497086A1
(en)
|
2002-08-30 |
2004-03-11 |
Becton, Dickinson And Company |
Method of controlling pharmacokinetics of immunomodulatory compounds
|
|
KR20120104412A
(ko)
|
2002-09-06 |
2012-09-20 |
인설트 테라페틱스, 인코퍼레이티드 |
공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
|
|
WO2004022629A2
(en)
|
2002-09-09 |
2004-03-18 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
|
US7534872B2
(en)
|
2002-09-27 |
2009-05-19 |
Syngen, Inc. |
Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis
|
|
ES2744275T3
(es)
|
2002-10-17 |
2020-02-24 |
Genmab As |
Anticuerpos monoclonales humanos contra CD20 para su uso en el tratamiento de esclerosis múltiple
|
|
WO2004038018A1
(ja)
|
2002-10-22 |
2004-05-06 |
Eisai Co., Ltd. |
分裂停止後のドーパミン産生ニューロン前駆細胞に特異的に発現している遺伝子
|
|
US6896666B2
(en)
|
2002-11-08 |
2005-05-24 |
Kochamba Family Trust |
Cutaneous injection delivery under suction
|
|
WO2004048594A2
(en)
|
2002-11-21 |
2004-06-10 |
Epicentre Technologies |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
|
US7491234B2
(en)
|
2002-12-03 |
2009-02-17 |
Boston Scientific Scimed, Inc. |
Medical devices for delivery of therapeutic agents
|
|
AU2003288467A1
(en)
|
2002-12-13 |
2004-07-09 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
DE60332957D1
(de)
|
2002-12-16 |
2010-07-22 |
Genentech Inc |
Immunoglobulinvarianten und deren verwendungen
|
|
CA2508985A1
(en)
|
2002-12-23 |
2004-07-15 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
|
US7169892B2
(en)
|
2003-01-10 |
2007-01-30 |
Astellas Pharma Inc. |
Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
|
|
US20080227085A1
(en)
|
2003-01-17 |
2008-09-18 |
Pellegrini Matthew C |
Methods and Systems for the Identification of Rna Regulatory Sequences and Compounds that Modulate their Function
|
|
CA2514184C
(en)
|
2003-01-21 |
2016-04-12 |
Ptc Therapeutics, Inc. |
Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
|
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
|
US8426194B2
(en)
|
2003-01-21 |
2013-04-23 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating VEGF expression
|
|
US20040147027A1
(en)
|
2003-01-28 |
2004-07-29 |
Troy Carol M. |
Complex for facilitating delivery of dsRNA into a cell and uses thereof
|
|
CN1768139A
(zh)
|
2003-02-10 |
2006-05-03 |
独立行政法人产业技术总合研究所 |
通过dna干扰调控基因的表达
|
|
WO2004071439A2
(en)
|
2003-02-10 |
2004-08-26 |
Elan Pharmaceuticals, Inc. |
Immunoglobulin formulation and method of preparation thereof
|
|
US20040167090A1
(en)
|
2003-02-21 |
2004-08-26 |
Monahan Sean D. |
Covalent modification of RNA for in vitro and in vivo delivery
|
|
CA2450289A1
(en)
|
2003-03-20 |
2005-05-19 |
Imclone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
|
US7320961B2
(en)
|
2003-03-24 |
2008-01-22 |
Abbott Laboratories |
Method for treating a disease, disorder or adverse effect caused by an elevated serum concentration of an UGT1A1 substrate
|
|
US7704712B2
(en)
|
2003-03-25 |
2010-04-27 |
Stratagene California |
DNA polymerase fusions and uses thereof
|
|
US20040242502A1
(en)
|
2003-04-08 |
2004-12-02 |
Galenica Pharmaceuticals, Inc. |
Semi-synthetic saponin analogs with carrier and immune stimulatory activities for DNA and RNA vaccines
|
|
NZ587776A
(en)
|
2003-04-09 |
2012-03-30 |
Genentech Inc |
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-alpha inhibitor using anti-CD20 antibody
|
|
EP1620140B1
(en)
|
2003-05-05 |
2013-10-09 |
Ben-Gurion University Of The Negev Research And Development Authority |
Injectable cross-linked polymeric preparations and uses thereof
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
ATE497783T1
(de)
|
2003-05-06 |
2011-02-15 |
Syntonix Pharmaceuticals Inc |
Gerinnungsfaktor vii-fc chimäre proteine zur behandlung von hämostatischen krankheiten
|
|
US20040226556A1
(en)
|
2003-05-13 |
2004-11-18 |
Deem Mark E. |
Apparatus for treating asthma using neurotoxin
|
|
US9567591B2
(en)
|
2003-05-15 |
2017-02-14 |
Mello Biotechnology, Inc. |
Generation of human embryonic stem-like cells using intronic RNA
|
|
GB0313132D0
(en)
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
|
EP1636385A4
(en)
|
2003-06-24 |
2010-06-02 |
Mirus Bio Corp |
INHIBITION OF GENE FUNCTION BY IN VIVO DISTRIBUTION OF GENE EXPRESSION INHIBITORS BASED ON POLYNUCLEOTIDES IN MAMMALIAN CELLS
|
|
GB0316089D0
(en)
|
2003-07-09 |
2003-08-13 |
Xo Bioscience Ltd |
Differentiation method
|
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
|
US7575572B2
(en)
|
2003-07-15 |
2009-08-18 |
Spinal Generations, Llc |
Method and device for delivering medicine to bone
|
|
US20050013870A1
(en)
|
2003-07-17 |
2005-01-20 |
Toby Freyman |
Decellularized extracellular matrix of conditioned body tissues and uses thereof
|
|
KR101254371B1
(ko)
|
2003-07-18 |
2013-05-02 |
암젠 프레몬트 인코포레이티드 |
간세포 성장인자에 결합하는 분리된 항체
|
|
EP1648914A4
(en)
|
2003-07-31 |
2009-12-16 |
Regulus Therapeutics Inc |
OLIGOMERIC COMPOUNDS AND COMPOSITIONS USEFUL FOR MODULATING SMALL NON-CODING RNA
|
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
|
US8668926B1
(en)
|
2003-09-15 |
2014-03-11 |
Shaker A. Mousa |
Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
|
|
US7135010B2
(en)
|
2003-09-30 |
2006-11-14 |
Damage Control Surgical Technologies, Inc. |
Method and apparatus for rapid deployment chest drainage
|
|
CA2541138A1
(en)
|
2003-10-06 |
2005-05-06 |
Novartis Ag |
Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
|
|
US20050130201A1
(en)
|
2003-10-14 |
2005-06-16 |
Dharmacon, Inc. |
Splint-assisted enzymatic synthesis of polyribounucleotides
|
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
|
JP4653109B2
(ja)
|
2003-11-05 |
2011-03-16 |
ロシュ グリクアート アクチェンゲゼルシャフト |
高められたＦｃレセプター結合親和性及びエフェクター機能をもつＣＤ２０抗体
|
|
WO2005047536A2
(en)
|
2003-11-13 |
2005-05-26 |
Novartis Ag |
Detection of genomic amplification and deletion in cancer
|
|
US20070054278A1
(en)
|
2003-11-18 |
2007-03-08 |
Applera Corporation |
Polymorphisms in nucleic acid molecules encoding human enzyme proteins, methods of detection and uses thereof
|
|
US7998119B2
(en)
|
2003-11-18 |
2011-08-16 |
Nano Pass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
|
US7699852B2
(en)
|
2003-11-19 |
2010-04-20 |
Zimmer Spine, Inc. |
Fenestrated bone tap and method
|
|
US20050153333A1
(en)
|
2003-12-02 |
2005-07-14 |
Sooknanan Roy R. |
Selective terminal tagging of nucleic acids
|
|
WO2005055945A2
(en)
|
2003-12-08 |
2005-06-23 |
Gel-Del Technologies, Inc. |
Mucoadhesive drug delivery devices and methods of making and using thereof
|
|
US7674884B2
(en)
|
2003-12-10 |
2010-03-09 |
Novimmune S.A. |
Neutralizing antibodies and methods of use thereof
|
|
WO2005084180A2
(en)
|
2003-12-19 |
2005-09-15 |
University Of Cincinnati |
Polyamides and polyamide complexes for delivery of oligonucleotide decoys
|
|
EP3718564B1
(en)
|
2003-12-23 |
2023-10-11 |
Genentech, Inc. |
Novel anti-il 13 antibodies and uses thereof
|
|
US7150726B2
(en)
|
2004-01-23 |
2006-12-19 |
Norfolk Medical |
Device for subcutaneous infusion of fluids
|
|
EP1713514B1
(en)
|
2004-01-28 |
2021-11-24 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
|
DK1716233T3
(da)
|
2004-01-30 |
2009-10-26 |
Maxygen Holdings Ltd |
Reguleret stopkodongennemlæsning
|
|
US7309487B2
(en)
|
2004-02-09 |
2007-12-18 |
George Inana |
Methods and compositions for detecting and treating retinal diseases
|
|
US20050232919A1
(en)
|
2004-02-12 |
2005-10-20 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
|
US20070265220A1
(en)
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
|
WO2005090405A1
(ja)
|
2004-03-24 |
2005-09-29 |
Chugai Seiyaku Kabushiki Kaisha |
インターロイキン－６受容体に対するヒト型化抗体のサブタイプ
|
|
WO2005098433A2
(en)
|
2004-04-01 |
2005-10-20 |
Novartis Ag |
Diagnostic assays for alzheimer’s disease
|
|
JP4981660B2
(ja)
|
2004-04-12 |
2012-07-25 |
アラーガン、インコーポレイテッド |
マルチサイト注射システム
|
|
JP5848861B2
(ja)
|
2004-04-20 |
2016-01-27 |
ジェンマブ エー／エスＧｅｎｍａｂ Ａ／Ｓ |
Ｃｄ２０に対するヒトモノクローナル抗体
|
|
ES2246694B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Nanoparticulas pegiladas.
|
|
US20080119645A1
(en)
|
2004-05-05 |
2008-05-22 |
Isis Pharmaceuticals, Inc. |
Amidites and Methods of Rna Synthesis
|
|
EP2072040B1
(en)
|
2004-05-12 |
2013-05-01 |
Baxter International Inc. |
Therapeutic use of nucleic acid micropheres
|
|
US20080103053A1
(en)
|
2005-11-22 |
2008-05-01 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
|
US8012747B2
(en)
|
2004-06-01 |
2011-09-06 |
San Diego State University Foundation |
Expression system
|
|
EP1781593B1
(en)
|
2004-06-07 |
2011-12-14 |
Protiva Biotherapeutics Inc. |
Cationic lipids and methods of use
|
|
EP1766035B1
(en)
|
2004-06-07 |
2011-12-07 |
Protiva Biotherapeutics Inc. |
Lipid encapsulated interfering rna
|
|
WO2005123114A2
(en)
|
2004-06-11 |
2005-12-29 |
Trustees Of Tufts College |
Silk-based drug delivery system
|
|
US8338648B2
(en)
|
2004-06-12 |
2012-12-25 |
Signum Biosciences, Inc. |
Topical compositions and methods for epithelial-related conditions
|
|
US7527947B2
(en)
|
2004-06-14 |
2009-05-05 |
Novozymes A/S |
Signal peptide for producing a polypeptide
|
|
WO2006046978A2
(en)
|
2004-06-28 |
2006-05-04 |
Argos Therapeutics, Inc. |
Cationic peptide-mediated transformation
|
|
ES2390082T5
(es)
|
2004-06-30 |
2018-01-19 |
Nektar Therapeutics |
Conjugados de resto de Factor IX y polímeros
|
|
US20070292445A1
(en)
|
2004-07-06 |
2007-12-20 |
Transpharma Medical Ltd. |
Delivery system for transdermal immunization
|
|
DE102004035227A1
(de)
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen
|
|
CA2574088C
(en)
|
2004-07-21 |
2013-09-17 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
|
US7603349B1
(en)
|
2004-07-29 |
2009-10-13 |
Yahoo! Inc. |
User interfaces for search systems using in-line contextual queries
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
JP5192234B2
(ja)
|
2004-08-10 |
2013-05-08 |
アルナイラム ファーマシューティカルズ， インコーポレイテッド |
化学修飾オリゴヌクレオチド
|
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
|
CA2478458A1
(en)
|
2004-08-20 |
2006-02-20 |
Michael Panzara |
Treatment of pediatric multiple sclerosis
|
|
MX2007002294A
(es)
|
2004-08-26 |
2007-10-19 |
Engeneic Molecular Delivery Pty Ltd |
Suministro de acidos nucleicos funcionales a celulas mamiferas via minicelulas intactas, derivadas bacterialmente.
|
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
|
US7501486B2
(en)
|
2004-09-07 |
2009-03-10 |
Burnham Institute For Medical Research |
Peptides that selectively home to heart vasculature and related conjugates and methods
|
|
US8663599B1
(en)
|
2004-10-05 |
2014-03-04 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
|
WO2006041088A1
(ja)
|
2004-10-12 |
2006-04-20 |
Tissue Targeting Japan Inc. |
脳移行性骨髄前駆細胞
|
|
MX2007004479A
(es)
|
2004-10-13 |
2007-06-18 |
Ptc Therapeutics Inc |
Compuestoss para supresion sin sentido y metodos para su uso.
|
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
|
WO2006047842A2
(en)
|
2004-11-08 |
2006-05-11 |
K.U. Leuven Research And Development |
Modified nucleosides for rna interference
|
|
CA2587216C
(en)
|
2004-11-18 |
2014-11-18 |
Nanopass Technologies Ltd. |
System and method for delivering fluid into flexible biological barrier
|
|
US8946444B2
(en)
|
2004-11-23 |
2015-02-03 |
Ptc Therapeutics, Inc. |
Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control
|
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
|
EP1856179B1
(en)
|
2004-12-10 |
2013-05-15 |
Kala Pharmaceuticals, Inc. |
Functionalized poly (ether-anhydride) block copolymers
|
|
US9068969B2
(en)
|
2004-12-28 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Cell based methods and systems for the identification of RNA regulatory sequences and compounds that modulate their functions
|
|
US8535702B2
(en)
|
2005-02-01 |
2013-09-17 |
Boston Scientific Scimed, Inc. |
Medical devices having porous polymeric regions for controlled drug delivery and regulated biocompatibility
|
|
WO2007086883A2
(en)
|
2005-02-14 |
2007-08-02 |
Sirna Therapeutics, Inc. |
Cationic lipids and formulated molecular compositions containing them
|
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
US20060263338A1
(en)
|
2005-03-04 |
2006-11-23 |
Jacoby Douglas B |
Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
|
|
EP2290363B1
(en)
|
2005-03-11 |
2014-01-08 |
Firalis SAS |
Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds
|
|
JP4793806B2
(ja)
|
2005-03-22 |
2011-10-12 |
Ｔｔｉ・エルビュー株式会社 |
イオントフォレーシス装置
|
|
US8415325B2
(en)
|
2005-03-31 |
2013-04-09 |
University Of Delaware |
Cell-mediated delivery and targeted erosion of noncovalently crosslinked hydrogels
|
|
EP2083088A3
(en)
|
2005-04-07 |
2009-10-14 |
Novartis Vaccines and Diagnostics, Inc. |
Cancer-related genes
|
|
AU2006235276A1
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics Inc. |
CACNA1E in cancer diagnosis, detection and treatment
|
|
US8273339B2
(en)
|
2005-04-12 |
2012-09-25 |
Nektar Therapeutics |
Polymer-based compositions and conjugates of antimicrobial agents
|
|
CN101203611B
(zh)
|
2005-04-19 |
2013-08-14 |
巴斯福植物科学有限公司 |
控制基因表达的改良方法
|
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
|
US7850656B2
(en)
|
2005-04-29 |
2010-12-14 |
Warsaw Orthopedic, Inc. |
Devices and methods for delivering medical agents
|
|
DK2161336T4
(en)
|
2005-05-09 |
2017-04-24 |
Ono Pharmaceutical Co |
Human monoclonal antibodies for programmed death 1 (PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapies
|
|
US20070072175A1
(en)
|
2005-05-13 |
2007-03-29 |
Biogen Idec Ma Inc. |
Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof
|
|
US20060265771A1
(en)
|
2005-05-17 |
2006-11-23 |
Lewis David L |
Monitoring microrna expression and function
|
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
|
HUE027013T2
(en)
|
2005-05-27 |
2016-10-28 |
Ospedale San Raffaele Srl |
A gene vector containing MI-RNA
|
|
US20090208500A1
(en)
|
2005-06-03 |
2009-08-20 |
Genentech, Inc. |
Method of producing antibodies with improved function
|
|
JP2008541737A
(ja)
|
2005-06-03 |
2008-11-27 |
サウザーン アデレード ヘルス サービス−ファインダーズ メディカル センター |
マイクロｒｎａ発現の変化した細胞を標的とすること
|
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
|
US7691086B2
(en)
|
2005-06-14 |
2010-04-06 |
Tengiz Tkebuchava |
Catheter for introduction of medications to the tissues of a heart or other organ
|
|
BRPI0611872B8
(pt)
|
2005-06-16 |
2021-05-25 |
Nektar Therapeutics |
reagente polimérico, conjugado, método para preparação de um conjugado e composição farmacêutica
|
|
US20110182805A1
(en)
|
2005-06-17 |
2011-07-28 |
Desimone Joseph M |
Nanoparticle fabrication methods, systems, and materials
|
|
US8202835B2
(en)
|
2005-06-17 |
2012-06-19 |
Yitzchak Hillman |
Disease treatment via antimicrobial peptides or their inhibitors
|
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
KR20080025181A
(ko)
|
2005-06-30 |
2008-03-19 |
아케믹스 코포레이션 |
완전 2'-변형된 핵산 전사체를 생성하기 위한 물질 및 방법
|
|
WO2007014363A2
(en)
|
2005-07-27 |
2007-02-01 |
Genentech, Inc. |
Vectors for inducible expression of hairpin rna and use thereof
|
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
|
HUE043492T2
(hu)
|
2005-08-23 |
2019-08-28 |
Univ Pennsylvania |
Módosított nukleozidokat tartalmazó RNS és eljárások az alkalmazására
|
|
US20070048741A1
(en)
|
2005-08-24 |
2007-03-01 |
Getts Robert C |
Methods and kits for sense RNA synthesis
|
|
CA2620420A1
(en)
|
2005-08-24 |
2007-03-01 |
The Scripps Research Institute |
Translation enhancer-element dependent vector systems
|
|
ES2443529T3
(es)
|
2005-09-01 |
2014-02-19 |
Novartis Vaccines And Diagnostics Gmbh |
Vacunación múltiple incluyendo meningococo del serogrupo C
|
|
ATE499112T1
(de)
|
2005-09-01 |
2011-03-15 |
Celgene Corp |
Immunologische verwendungen von immunmodulatorischen verbindungen für einen impfstoff und therapie gegen infektionskrankheiten
|
|
US8420605B2
(en)
|
2005-09-07 |
2013-04-16 |
The University Of Strathclyde |
Hydrogel compositions
|
|
US20120021042A1
(en)
|
2005-09-15 |
2012-01-26 |
Steffen Panzner |
Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances
|
|
US20070185432A1
(en)
|
2005-09-19 |
2007-08-09 |
Transport Pharmaceuticals, Inc. |
Electrokinetic system and method for delivering methotrexate
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
US20070087437A1
(en)
|
2005-10-14 |
2007-04-19 |
Jifan Hu |
Methods for rejuvenating cells in vitro and in vivo
|
|
US8012096B2
(en)
|
2005-10-17 |
2011-09-06 |
Cardiogenesis Corporation |
Surgical device and method for performing combination revascularization and therapeutic substance delivery to tissue
|
|
ATE539765T1
(de)
|
2005-11-04 |
2012-01-15 |
Novartis Vaccines & Diagnostic |
Grippeimpfstoffe mit kombinationen aus teilchenförmigen adjuvantien und immunverstärkern
|
|
US20070105124A1
(en)
|
2005-11-08 |
2007-05-10 |
Getts Robert C |
Methods and kits for nucleic acid amplification
|
|
AU2006314757A1
(en)
|
2005-11-18 |
2007-05-24 |
Bioline Limited |
A method for enhancing enzymatic DNA polymerase reactions
|
|
KR101866623B1
(ko)
|
2005-11-28 |
2018-07-04 |
젠맵 에이/에스 |
재조합 １가 항체 및 그의 제조 방법
|
|
AU2005338632B2
(en)
|
2005-11-30 |
2010-05-20 |
Epicentre Technologies Corporation |
Selective terminal tagging of nucleic acids
|
|
TWI389709B
(zh)
|
2005-12-01 |
2013-03-21 |
Novartis Ag |
經皮治療系統
|
|
US8603457B2
(en)
|
2005-12-02 |
2013-12-10 |
University Of Rochester |
Nonsense suppression and genetic codon alteration by targeted modification
|
|
EP1954252B1
(en)
|
2005-12-02 |
2016-02-03 |
GlaxoSmithKline Biologicals SA |
Nanoparticles for use in immunogenic compositions
|
|
EP1969000A2
(en)
|
2005-12-06 |
2008-09-17 |
Centre National de la Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
US7579318B2
(en)
|
2005-12-06 |
2009-08-25 |
Centre De La Recherche De La Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
RU2008127252A
(ru)
|
2005-12-08 |
2010-01-20 |
Новартис АГ (CH) |
Эффекты ингибиторов fgfr3 на транскрипцию генов
|
|
EP4223769A3
(en)
|
2005-12-13 |
2023-11-01 |
Kyoto University |
Nuclear reprogramming factor
|
|
JP2009519033A
(ja)
|
2005-12-16 |
2009-05-14 |
ディアト |
核酸を細胞に送達するための細胞貫通ペプチド結合体
|
|
ES2536423T3
(es)
|
2006-01-05 |
2015-05-25 |
The Ohio State University Research Foundation |
Métodos basados en microARN para el diagnóstico de cáncer de próstata
|
|
WO2007081680A2
(en)
|
2006-01-05 |
2007-07-19 |
The Ohio State University Research Foundation |
Microrna expression abnormalities in pancreatic endocrine and acinar tumors
|
|
CA2636867C
(en)
|
2006-01-13 |
2015-12-01 |
The Trustees Of The University Of Pennsylvania |
Vaccines and immunotherapeutics using codon optimized il-15 and methods for using the same
|
|
JP5342881B2
(ja)
|
2006-01-27 |
2013-11-13 |
アイシス ファーマシューティカルズ， インコーポレーテッド |
６−修飾された二環式核酸類似体
|
|
US20070178103A1
(en)
|
2006-01-30 |
2007-08-02 |
Fey Georg H |
CD19-specific immunotoxin and treatment method
|
|
US8476234B2
(en)
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
|
EP1991560B1
(en)
|
2006-02-20 |
2018-04-04 |
Ewha University-Industry Collaboration Foundation |
Peptide having cell membrane penetrating activity
|
|
KR101513732B1
(ko)
|
2006-02-21 |
2015-04-21 |
넥타르 테라퓨틱스 |
분할된 분해가능한 폴리머 및 이로부터 제조된 컨주게이트
|
|
US20080038278A1
(en)
|
2006-02-24 |
2008-02-14 |
Jingsong Cao |
GPAT3 encodes a mammalian, microsomal acyl-coa:glycerol 3- phosphate acyltransferase
|
|
JP2009527572A
(ja)
|
2006-02-24 |
2009-07-30 |
ノバルティス アーゲー |
免疫原性組成物に使用するための生分解性ポリマーおよびカチオン性多糖を含むミクロ粒子
|
|
US7910152B2
(en)
|
2006-02-28 |
2011-03-22 |
Advanced Cardiovascular Systems, Inc. |
Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
|
|
CA3127202A1
(en)
|
2006-02-28 |
2007-09-07 |
Biogen Ma Inc. |
Methods of treating inflammatory and autoimmune diseases with natalizumab
|
|
EP1991706B1
(en)
|
2006-03-02 |
2014-01-15 |
The Ohio State University Research Foundation |
Microrna expression profile associated with pancreatic cancer
|
|
GB0605217D0
(en)
|
2006-03-15 |
2006-04-26 |
Novartis Ag |
Method and compositions for assessing acute rejection
|
|
WO2007109244A2
(en)
|
2006-03-21 |
2007-09-27 |
Morehouse School Of Medicine |
Novel nanoparticles for delivery of active agents
|
|
JP2009534309A
(ja)
|
2006-03-31 |
2009-09-24 |
マサチューセッツ インスティテュート オブ テクノロジー |
治療剤の標的化送達のためのシステム
|
|
CN101415405A
(zh)
|
2006-04-04 |
2009-04-22 |
Stc.Unm公司 |
用于药物递送的可溶胀颗粒
|
|
WO2007120863A2
(en)
|
2006-04-14 |
2007-10-25 |
Epicentre Technologies |
Kits and methods for generating 5' capped rna
|
|
EP1852127A1
(en)
|
2006-05-02 |
2007-11-07 |
Charité - Universitätsmedizin Berlin |
Use of a B-cell-depleting antibody for treatment of polyoma virus infections
|
|
EP2019691B1
(en)
|
2006-05-15 |
2020-08-12 |
Massachusetts Institute of Technology |
Polymers for functional particles
|
|
CA2649810A1
(en)
|
2006-05-24 |
2007-11-29 |
Laboratoires Serono S.A. |
Cladribine regimen for treating multiple sclerosis
|
|
EP3045532A1
(en)
|
2006-06-02 |
2016-07-20 |
President and Fellows of Harvard College |
Protein surface remodeling
|
|
US20090018566A1
(en)
|
2006-06-30 |
2009-01-15 |
Artheromed, Inc. |
Atherectomy devices, systems, and methods
|
|
EP2046383B1
(en)
|
2006-07-04 |
2014-11-19 |
Genmab A/S |
Cd20 binding molecules for the treatment of copd
|
|
ES2362376T3
(es)
|
2006-07-07 |
2011-07-04 |
Aarhus Universitet |
Nanopartículas para la administración de ácido nucleico.
|
|
DK2038310T3
(da)
|
2006-07-12 |
2010-09-27 |
Novartis Ag |
Aktinisk tværbindelige copolymerer til fremstilling af kontaktlinser
|
|
WO2008011519A2
(en)
|
2006-07-20 |
2008-01-24 |
Novartis Ag |
Amigo-2 inhibitors for treating, diagnosing or detecting cancer
|
|
EP2054036B1
(en)
|
2006-07-24 |
2019-12-18 |
Singh-Broemer and Company, Inc. |
Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
|
|
JP2009544754A
(ja)
|
2006-07-28 |
2009-12-17 |
アプライド バイオシステムズ， エルエルシー |
ジヌクレオチドｍｒｎａキャップアナログ
|
|
EP2046954A2
(en)
|
2006-07-31 |
2009-04-15 |
Curevac GmbH |
NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT
|
|
DE102006035618A1
(de)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
|
CA2659337A1
(en)
|
2006-08-07 |
2008-02-14 |
Genzyme Corporation |
Combination therapy
|
|
US8658211B2
(en)
|
2006-08-18 |
2014-02-25 |
Arrowhead Madison Inc. |
Polyconjugates for in vivo delivery of polynucleotides
|
|
AU2007286059A1
(en)
|
2006-08-18 |
2008-02-21 |
Mdrna, Inc. |
Dicer substrate RNA peptide conjugates and methods for RNA therapeutics
|
|
WO2008030988A2
(en)
|
2006-09-06 |
2008-03-13 |
The Regents Of The University Of California |
Selectively targeted antimicrobial peptides and the use thereof
|
|
MY170607A
(en)
|
2006-09-07 |
2019-08-20 |
Crucell Holland Bv |
Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof
|
|
DE602007012559D1
(de)
|
2006-09-08 |
2011-03-31 |
Univ Johns Hopkins |
H die schleimhaut
|
|
DE602007010807D1
(de)
|
2006-09-08 |
2011-01-05 |
Arbel Medical Ltd |
Vorrichtung für kombinierte behandlung
|
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
|
EP2115138A2
(en)
|
2006-09-19 |
2009-11-11 |
Asuragen, Inc. |
Micrornas differentially expressed in pancreatic diseases and uses thereof
|
|
GB0619182D0
(en)
|
2006-09-29 |
2006-11-08 |
Leuven K U Res & Dev |
Oligonucleotide arrays
|
|
MX2009003548A
(es)
|
2006-10-03 |
2009-04-15 |
Alnylam Pharmaceuticals Inc |
Formulaciones que contienen lipidos.
|
|
RU2492872C2
(ru)
|
2006-10-05 |
2013-09-20 |
Дзе Джонс Хопкинс Юниверсити |
Вододиспергируемые пероральные, парентеральные и местные композиции для плохо растворимых в воде лекарственных препаратов, включающие улучшающие их свойства полимерные наночастицы
|
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
|
EP2087135B8
(en)
|
2006-11-01 |
2013-07-24 |
The Ohio State University Research Foundation |
Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma
|
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
|
US7999087B2
(en)
|
2006-11-15 |
2011-08-16 |
Agilent Technologies, Inc. |
2′-silyl containing thiocarbonate protecting groups for RNA synthesis
|
|
US8242258B2
(en)
|
2006-12-03 |
2012-08-14 |
Agilent Technologies, Inc. |
Protecting groups for RNA synthesis
|
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
|
CN101553252A
(zh)
|
2006-12-06 |
2009-10-07 |
诺华有限公司 |
包含来自于四株流感病毒的抗原的疫苗
|
|
WO2008073915A2
(en)
|
2006-12-08 |
2008-06-19 |
Asuragen, Inc. |
Micrornas differentially expressed in leukemia and uses thereof
|
|
US9034348B2
(en)
|
2006-12-11 |
2015-05-19 |
Chi2Gel Ltd. |
Injectable chitosan mixtures forming hydrogels
|
|
EP2124999B1
(en)
|
2006-12-18 |
2012-10-03 |
Acceleron Pharma, Inc. |
Activin-actrii antagonists and uses for treating anemia
|
|
EP2120859B1
(en)
|
2006-12-21 |
2013-11-20 |
Stryker Corporation |
Sustained-release formulations comprising bmp-7 crystals
|
|
DK2104739T3
(da)
|
2006-12-21 |
2013-10-07 |
Novozymes Inc |
Modificerede messenger-RNA-stabiliseringssekvenser til ekspression af gener i bakterieceller
|
|
DE102006061015A1
(de)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC
|
|
AU2007337810B2
(en)
|
2006-12-22 |
2014-02-13 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
US7699803B2
(en)
|
2007-01-03 |
2010-04-20 |
Medtronic Vascular, Inc. |
Devices and methods for injection of multiple-component therapies
|
|
US8338166B2
(en)
|
2007-01-04 |
2012-12-25 |
Lawrence Livermore National Security, Llc |
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
WO2008091799A2
(en)
|
2007-01-22 |
2008-07-31 |
The Trustees Of Columbia University In The City Of New York |
Cell-based methods for identifying inhibitors of parkinson's disease-associated lrrk2 mutants
|
|
JP4866467B2
(ja)
|
2007-01-30 |
2012-02-01 |
エピバックス インコーポレーテッド |
調節性ｔ細胞エピトープ、組成物およびその使用
|
|
TWI432449B
(zh)
|
2007-02-02 |
2014-04-01 |
Acceleron Pharma Inc |
衍生自ＡｃｔＲＩＩＢ的變體與其用途
|
|
US8859229B2
(en)
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
|
WO2008096370A2
(en)
|
2007-02-05 |
2008-08-14 |
Natco Pharma Limited |
An efficient and novel purification method of recombinant hg-csf
|
|
US8333799B2
(en)
|
2007-02-12 |
2012-12-18 |
C. R. Bard, Inc. |
Highly flexible stent and method of manufacture
|
|
EP2131848A4
(en)
|
2007-02-16 |
2012-06-27 |
Merck Sharp & Dohme |
COMPOSITIONS AND METHODS FOR REINFORCED ACTIVITY OF BIOLOGICAL ACTIVE MOLECULES
|
|
US8242087B2
(en)
|
2007-02-27 |
2012-08-14 |
K.U.Leuven Research & Development |
Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents
|
|
JP5467415B2
(ja)
|
2007-03-02 |
2014-04-09 |
ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
タンパク質製造の改良
|
|
EP1964922A1
(en)
|
2007-03-02 |
2008-09-03 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Improvement of protein production
|
|
US8029496B2
(en)
|
2007-03-05 |
2011-10-04 |
Ebrahim Versi |
Method and device for delivering drug to the trigone of the bladder
|
|
JP5249248B2
(ja)
|
2007-03-05 |
2013-07-31 |
ワシントン ユニバーシティー |
膜組み込みペプチドのためのナノ粒子輸送システム
|
|
JP2010521966A
(ja)
|
2007-03-20 |
2010-07-01 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
α４β７インテグリンに結合するヒト化免疫グロブリンをコードする核酸
|
|
EP2152358B1
(en)
|
2007-04-27 |
2011-03-02 |
Echo Therapeutics, Inc. |
Skin permeation device for analyte sensing or transdermal drug delivery
|
|
US20100086554A1
(en)
|
2007-04-30 |
2010-04-08 |
Smithkline Beecham Corporation |
Methods for administering anti-il-5 antibodies
|
|
WO2008135855A2
(en)
|
2007-05-03 |
2008-11-13 |
Pfizer Products Inc. |
Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
|
|
NZ580707A
(en)
|
2007-05-04 |
2011-11-25 |
Marina Biotech Inc |
Acylated cationic amino acids and uses thereof
|
|
US7682789B2
(en)
|
2007-05-04 |
2010-03-23 |
Ventana Medical Systems, Inc. |
Method for quantifying biomolecules conjugated to a nanoparticle
|
|
WO2009023311A2
(en)
|
2007-05-07 |
2009-02-19 |
Alba Therapeutics Corporation |
Transcutaneous delivery of therapeutic agents
|
|
JP5296328B2
(ja)
|
2007-05-09 |
2013-09-25 |
独立行政法人理化学研究所 |
１本鎖環状ｒｎａおよびその製造方法
|
|
EP2476689B1
(en)
|
2007-05-10 |
2015-10-21 |
Agilent Technologies, Inc. |
Thiocarbon-protecting groups for RNA synthesis
|
|
WO2008144365A2
(en)
|
2007-05-17 |
2008-11-27 |
Novartis Ag |
Method for making dry powder compositions containing ds-rna based on supercritical fluid technology
|
|
JP2010529954A
(ja)
|
2007-05-22 |
2010-09-02 |
ノバルティス アーゲー |
Ｆｇｆ２１関連障害を処置、診断および検出する方法
|
|
WO2008147974A1
(en)
|
2007-05-23 |
2008-12-04 |
University Of South Florida |
Micro-rnas modulating immunity and inflammation
|
|
EP2160464B1
(en)
|
2007-05-30 |
2014-05-21 |
Northwestern University |
Nucleic acid functionalized nanoparticles for therapeutic applications
|
|
WO2008151058A2
(en)
|
2007-05-30 |
2008-12-11 |
The General Hospital Corporation |
Methods of generating pluripotent cells from somatic cells
|
|
WO2008154098A2
(en)
|
2007-06-07 |
2008-12-18 |
Wisconsin Alumni Research Foundation |
Reagents and methods for mirna expression analysis and identification of cancer biomarkers
|
|
SI2167523T1
(sl)
|
2007-06-19 |
2014-09-30 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Sinteza in uporaba anti-reverznih fosforotioatnih analogov kape obveščevalne RNA
|
|
US8039214B2
(en)
|
2007-06-29 |
2011-10-18 |
Cellscript, Inc. |
Synthesis of tagged nucleic acids
|
|
US8367318B2
(en)
|
2007-07-23 |
2013-02-05 |
Dharmacon, Inc. |
Screening of micro-RNA cluster inhibitor pools
|
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
|
ES2868136T3
(es)
|
2007-08-14 |
2021-10-21 |
Hutchinson Fred Cancer Res |
Disposición de matriz de agujas y método para administrar agentes terapéuticos
|
|
WO2009024599A1
(en)
|
2007-08-23 |
2009-02-26 |
Novartis Ag |
Methods for detecting oligonucleotides
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
ES2449070T3
(es)
|
2007-09-05 |
2014-03-18 |
F. Hoffmann-La Roche Ag |
Terapia de combinación con anticuerpos anti-CD20 de tipo I y tipo II
|
|
US8506928B2
(en)
|
2007-09-07 |
2013-08-13 |
The Regents Of The University Of California |
Methods and compounds for targeting tissues
|
|
US20130108663A1
(en)
|
2007-09-14 |
2013-05-02 |
Vrije Universiteit Brussel |
Enhancing the t-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and their use in vaccination
|
|
WO2009039198A2
(en)
|
2007-09-17 |
2009-03-26 |
The Trustees Of The University Of Pennsylvania |
Generation of hyperstable mrnas
|
|
EP3156414B1
(en)
|
2007-09-26 |
2019-12-04 |
Intrexon Corporation |
Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
|
|
AU2008304313B2
(en)
|
2007-09-26 |
2013-01-10 |
Oregon Health & Science University |
Cyclic undecapeptides and derivatives as multiple sclerosis therapies
|
|
JP5410434B2
(ja)
|
2007-09-28 |
2014-02-05 |
バインド セラピューティックス インコーポレイテッド |
ナノ粒子を用いた癌細胞の標的化
|
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
|
US8470560B2
(en)
|
2007-10-03 |
2013-06-25 |
The United States Of America As Represented By The Secretary Of The Army |
CR-2 binding peptide P28 as molecular adjuvant for DNA vaccines
|
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
|
EP2620157A3
(en)
|
2007-10-12 |
2013-10-16 |
Massachusetts Institute of Technology |
Vaccine nanotechnology
|
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
|
EP2205277B1
(en)
|
2007-10-22 |
2017-07-26 |
Genmab A/S |
Novel antibody therapies
|
|
KR20100113478A
(ko)
|
2007-11-01 |
2010-10-21 |
유니버시티 오브 로체스터 |
증가된 안정성을 갖는 재조합 인자 ⅴⅰⅰⅰ
|
|
KR20100088621A
(ko)
|
2007-11-09 |
2010-08-09 |
노파르티스 아게 |
항-ｃｄ40 항체의 용도
|
|
WO2009062348A1
(en)
|
2007-11-14 |
2009-05-22 |
Institute Of Microbiology, Chinese Academy Of Sciences |
Methods for inhibiting influenza virus infection and their drugs
|
|
US20090137945A1
(en)
|
2007-11-28 |
2009-05-28 |
Claire Marquez |
Electro Collagen Induction Therapy Device
|
|
WO2009070653A1
(en)
|
2007-11-30 |
2009-06-04 |
The Ohio State University Research Foundation |
Microrna expression profiling and targeting in peripheral blood in lung cancer
|
|
DE112008003232T5
(de)
|
2007-11-30 |
2011-02-24 |
Glaxo Group Limited, Greenford |
Antigen-Bindungskonstrukte
|
|
EP2617828B1
(en)
|
2007-12-10 |
2014-09-24 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expression of factor VII gene
|
|
EP2584038B1
(en)
|
2007-12-11 |
2014-06-25 |
The Scripps Research Institute |
Compositions and methods related to mRNA translational enhancer elements
|
|
AU2008334948B2
(en)
|
2007-12-13 |
2014-11-20 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for prevention or treatment of RSV infection
|
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
|
JP2011507897A
(ja)
|
2007-12-21 |
2011-03-10 |
ジェネンテック， インコーポレイテッド |
リツキシマブ抵抗性関節リウマチ患者の治療
|
|
JP5645044B2
(ja)
*
|
2008-01-22 |
2014-12-24 |
独立行政法人医薬基盤研究所 |
遺伝子発現制御機構を含む新規Ａｄベクター
|
|
EP2248906A4
(en)
|
2008-01-23 |
2012-07-11 |
Ajinomoto Kk |
PROCESS FOR THE PREPARATION OF L-AMINO ACID
|
|
US20100297750A1
(en)
|
2008-01-24 |
2010-11-25 |
Toru Natsume |
Polynucleotide or analogue thereof, and gene expression regulation method using the polynucleotide or the analogue thereof
|
|
KR101483715B1
(ko)
|
2008-01-31 |
2015-01-19 |
큐어백 게엠바하 |
면역증강제／애주번트인 화학식（ＮｕＧｌＸｍＧｎＮｖ）ａ를 포함하는 핵산 및 이의 유도체
|
|
EP2260110B1
(en)
|
2008-02-08 |
2014-11-12 |
Asuragen, INC. |
miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
|
|
WO2009101407A2
(en)
|
2008-02-11 |
2009-08-20 |
Cambridge Enterprise Limited |
Improved reprogramming of mammalian cells, and the cells obtained
|
|
DK2240155T3
(da)
|
2008-02-13 |
2012-09-17 |
Intarcia Therapeutics Inc |
Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
|
|
DE102008009920A1
(de)
|
2008-02-15 |
2009-08-20 |
Aj Innuscreen Gmbh |
Mobiles Gerät für die Nukleinsäureisolierung
|
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
|
JP2011517932A
(ja)
|
2008-02-28 |
2011-06-23 |
ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション |
ヒト慢性リンパ球性白血病（ｃｃｌ）と関連するマイクロｒｎａシグネチャーおよびその使用
|
|
US20100004313A1
(en)
|
2008-02-29 |
2010-01-07 |
Tbd |
Modified Poloxamers for Gene Expression and Associated Methods
|
|
JP2011514423A
(ja)
|
2008-03-14 |
2011-05-06 |
エーゲン、インコーポレイテッド |
生分解性架橋分枝状ポリ（アルキレンイミン）
|
|
EA201001467A1
(ru)
|
2008-03-14 |
2011-06-30 |
Биокон Лимитед |
Моноклональное антитело и способ его использования
|
|
CA2719786A1
(en)
|
2008-03-28 |
2009-10-01 |
Glaxosmithkline Llc |
Methods of treatment
|
|
ES2638448T3
(es)
|
2008-04-15 |
2017-10-20 |
Protiva Biotherapeutics Inc. |
Novedosas formulaciones de lípidos para la administración de ácidos nucleicos
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
EP2112235A1
(en)
|
2008-04-24 |
2009-10-28 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Compositions and methods for microRNA expression profiling of nasopharyngeal carcinoma
|
|
CN102036652B
(zh)
|
2008-04-25 |
2016-04-13 |
西北大学 |
适于螯合胆甾醇的纳米结构
|
|
EP2297182A4
(en)
|
2008-04-28 |
2012-08-15 |
Harvard College |
HIGHLY CHARGED PROTEINS USED FOR CELL PENETRATION
|
|
WO2009134717A1
(en)
|
2008-04-30 |
2009-11-05 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention |
Chimeric west nile/dengue viruses
|
|
US9394538B2
(en)
|
2008-05-07 |
2016-07-19 |
Shi-Lung Lin |
Development of universal cancer drugs and vaccines
|
|
EP2323716B1
(en)
|
2008-05-08 |
2015-03-04 |
MiniPumps, LLC |
Drug-delivery pumps
|
|
US8697098B2
(en)
|
2011-02-25 |
2014-04-15 |
South Dakota State University |
Polymer conjugated protein micelles
|
|
EP2620161A1
(en)
|
2008-05-13 |
2013-07-31 |
University of Washington |
Diblock copolymers and polynucleotide complexes thereof for delivery into cells
|
|
US9738680B2
(en)
|
2008-05-21 |
2017-08-22 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
5′ triphosphate oligonucleotide with blunt end and uses thereof
|
|
FR2931824B1
(fr)
|
2008-05-29 |
2014-11-28 |
Centre Nat Rech Scient |
Procede de synthese d'arn par voie chimique.
|
|
EP2297197B1
(en)
|
2008-05-29 |
2012-03-07 |
HanAll Biopharma Co., Ltd. |
Modified erythropoietin (epo)polypeptides that exhibit increased protease resistance and pharmaceutical compositions thereof
|
|
WO2009148528A2
(en)
|
2008-05-30 |
2009-12-10 |
Millennium Pharmaceuticals, Inc. |
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
|
|
US8540678B2
(en)
|
2008-06-06 |
2013-09-24 |
Wockhardt Ltd. |
Device and a system for delivery of biological material
|
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
|
TWI451876B
(zh)
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
|
JP2012501966A
(ja)
|
2008-06-16 |
2012-01-26 |
バインド バイオサイエンシズ インコーポレイテッド |
ビンカアルカロイド含有治療用ポリマーナノ粒子並びにその製造方法及び使用方法
|
|
PT2285350T
(pt)
|
2008-06-16 |
2018-01-04 |
Pfizer |
Métodos para a preparação de copolímeros em dibloco funcionalizados com agente de direcionamento para utilização no fabrico de nanopartículas terapêuticas
|
|
EA020954B1
(ru)
|
2008-06-16 |
2015-03-31 |
Бинд Терапьютикс, Инк. |
Загруженные лекарственным средством полимерные наночастицы, фармацевтическая композиция и способ лечения рака
|
|
US7799016B2
(en)
|
2008-06-20 |
2010-09-21 |
Pharmaco-Kinesis Corporation |
Magnetic breather pump and a method for treating a brain tumor using the same
|
|
CN105902482A
(zh)
|
2008-06-25 |
2016-08-31 |
Fe3医学有限公司 |
用于经皮递送治疗有效量的铁的贴片和方法
|
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
|
WO2010009065A2
(en)
|
2008-07-15 |
2010-01-21 |
Novartis Ag |
Amphipathic peptide compositions
|
|
WO2010009277A2
(en)
|
2008-07-15 |
2010-01-21 |
Novartis Ag |
Immunogenic amphipathic peptide compositions
|
|
WO2010018563A2
(en)
|
2008-08-12 |
2010-02-18 |
Rosetta Genomics Ltd. |
Compositions and methods for the prognosis of lymphoma
|
|
EP2326331A4
(en)
|
2008-08-18 |
2013-05-15 |
Merck Sharp & Dohme |
NEW LIPID NANOPARTICLES AND NEW COMPONENTS FOR THE RELEASE OF NUCLEIC ACIDS
|
|
WO2010024871A1
(en)
|
2008-08-26 |
2010-03-04 |
Med Institute, Inc. |
Balloon catheters having a plurality of needles for the injection of one or more therapeutic agents
|
|
WO2010025510A1
(en)
|
2008-09-03 |
2010-03-11 |
Xenome Ltd |
Libraries of peptide conjugates and methods for making them
|
|
US8309707B2
(en)
|
2008-09-06 |
2012-11-13 |
Chemgenes Corporation |
RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end
|
|
WO2010027903A2
(en)
|
2008-09-08 |
2010-03-11 |
Fred Hutchinson Cancer Research Center |
Lung cancer diagnosis
|
|
US20100087337A1
(en)
|
2008-09-10 |
2010-04-08 |
Bind Biosciences, Inc. |
High Throughput Fabrication of Nanoparticles
|
|
TW201438738A
(zh)
|
2008-09-16 |
2014-10-16 |
建南德克公司 |
治療進展型多發性硬化症之方法
|
|
WO2010033906A2
(en)
|
2008-09-19 |
2010-03-25 |
President And Fellows Of Harvard College |
Efficient induction of pluripotent stem cells using small molecule compounds
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
WO2010042490A1
(en)
|
2008-10-06 |
2010-04-15 |
Boston Medical Center Corporation |
A single lentiviral vector system for induced pluripotent (ips) stem cells derivation
|
|
EP2743265B1
(en)
|
2008-10-09 |
2017-03-15 |
Arbutus Biopharma Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
|
EP2349100B1
(en)
|
2008-10-10 |
2014-07-16 |
Kirk Promotion LTD. |
Infusion of drugs
|
|
US8535655B2
(en)
|
2008-10-10 |
2013-09-17 |
Polyactiva Pty Ltd. |
Biodegradable polymer—bioactive moiety conjugates
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
ITVI20080239A1
(it)
|
2008-10-14 |
2010-04-15 |
Antoine Assaf |
Apparato medicale per iniezioni multiple.
|
|
PT2937418T
(pt)
|
2008-10-20 |
2018-01-23 |
Alnylam Pharmaceuticals Inc |
Composições e métodos de inibição da expressão de transtirretina
|
|
US8603532B2
(en)
|
2008-10-20 |
2013-12-10 |
Massachusetts Institute Of Technology |
Nanostructures for drug delivery
|
|
US20120015899A1
(en)
|
2008-10-25 |
2012-01-19 |
Plant Bioscience, Limited |
Modified plant virus particles and uses therefor
|
|
US8969353B2
(en)
|
2008-11-07 |
2015-03-03 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
EA037404B1
(ru)
|
2008-11-10 |
2021-03-24 |
Арбутус Биофарма Корпорэйшн |
Липиды и композиции для доставки лекарственных средств
|
|
EP2364362B1
(en)
|
2008-11-12 |
2015-10-21 |
Ospedale San Raffaele S.r.l. |
Gene vector for inducing transgene-specific immune tolerance
|
|
US9074206B2
(en)
|
2008-11-13 |
2015-07-07 |
Fudan University |
Compositions and methods for micro-RNA expression profiling of colorectal cancer
|
|
WO2010057203A2
(en)
|
2008-11-17 |
2010-05-20 |
The Board Of Regents Of The University Of Texas System |
Hdl particles for delivery of nucleic acids
|
|
EP2191840A1
(en)
|
2008-11-28 |
2010-06-02 |
Sanofi-Aventis |
Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
|
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
|
EP2358902A1
(en)
|
2008-12-10 |
2011-08-24 |
Universität Regensburg |
Compositions and methods for micro-rna expression profiling of cancer stem cells
|
|
US8512964B2
(en)
|
2008-12-12 |
2013-08-20 |
The Regents Of The University Of California |
Targets for treatment of hypercholesterolemia
|
|
US8563041B2
(en)
|
2008-12-12 |
2013-10-22 |
Bind Therapeutics, Inc. |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
|
ES2776126T3
(es)
|
2008-12-15 |
2020-07-29 |
Pfizer |
Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos
|
|
WO2010080724A1
(en)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
|
JP2012515217A
(ja)
|
2009-01-16 |
2012-07-05 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
ベンダムスチンおよび抗−ｃｄ２０抗体の組合せを用いた癌治療
|
|
WO2010084371A1
(en)
|
2009-01-26 |
2010-07-29 |
Mitoprod |
Novel circular interfering rna molecules
|
|
EP2391343B1
(en)
|
2009-01-29 |
2017-03-01 |
Arbutus Biopharma Corporation |
Improved lipid formulation for the delivery of nucleic acids
|
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
|
US20140141089A1
(en)
|
2009-02-11 |
2014-05-22 |
Colorado School Of Mines |
Nanoparticles, Compositions Thereof, and Methods of Use, and Methods of Making the Same
|
|
KR20110126717A
(ko)
|
2009-02-24 |
2011-11-23 |
더 스크립스 리서치 인스티튜트 |
단백질 생성 증강을 위한 ｍｒｎａ １차 구조의 재구조화
|
|
WO2010141135A2
(en)
|
2009-03-05 |
2010-12-09 |
Trustees Of Boston University |
Bacteriophages expressing antimicrobial peptides and uses thereof
|
|
WO2010102066A1
(en)
|
2009-03-05 |
2010-09-10 |
Bend Research, Inc. |
Dextran polymer powder for inhalation administration of pharmaceuticals
|
|
KR20110128345A
(ko)
|
2009-03-13 |
2011-11-29 |
에젠, 인코포레이티드 |
생물학적 활성 ｒｎａ의 전달을 위한 조성물 및 방법
|
|
AU2010226434A1
(en)
|
2009-03-20 |
2011-10-13 |
Egen, Inc. |
Polyamine derivatives
|
|
US20120095077A1
(en)
|
2009-03-23 |
2012-04-19 |
University Of Utah Research Foundation |
Methods and compositions related to modified guanine bases for controlling off-target effects in rna interference
|
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
|
HUE026855T2
(en)
|
2009-04-03 |
2016-07-28 |
Univ Chicago |
Compositions and methods related to protein a (spa) variants
|
|
US9724404B2
(en)
|
2009-04-13 |
2017-08-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
HPV particles and uses thereof
|
|
EP2419137A4
(en)
|
2009-04-17 |
2013-01-09 |
Biogen Idec Inc |
COMPOSITIONS AND METHOD FOR TREATING ACUTE MYELOGENIC LEUKEMIA
|
|
KR20120022984A
(ko)
|
2009-04-21 |
2012-03-12 |
셀렉타 바이오사이언시즈, 인크. |
Ｔｈ１ 편향 반응을 제공하는 면역나노치료법
|
|
US10837020B2
(en)
*
|
2009-04-22 |
2020-11-17 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long RNA molecules
|
|
WO2010123501A1
(en)
|
2009-04-22 |
2010-10-28 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
|
EP3275900A1
(en)
|
2009-04-27 |
2018-01-31 |
Novartis AG |
Compositions and methods for increasing muscle growth
|
|
US8715736B2
(en)
|
2009-04-30 |
2014-05-06 |
Florida Agricultural And Mechanical University |
Nanoparticle formulations for skin delivery
|
|
US8287910B2
(en)
|
2009-04-30 |
2012-10-16 |
Intezyne Technologies, Inc. |
Polymeric micelles for polynucleotide encapsulation
|
|
CA3042927C
(en)
|
2009-05-05 |
2022-05-17 |
Arbutus Biopharma Corporation |
Lipid compositions for the delivery of therapeutic agents
|
|
EP2427574A2
(en)
|
2009-05-08 |
2012-03-14 |
The Ohio State University Research Foundation |
Microrna expression profiling and targeting in chronic obstructive pulmonary disease (copd) lung tissue and methods of use thereof
|
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
|
JP6282395B2
(ja)
|
2009-05-27 |
2018-02-21 |
セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． |
異なる放出速度の構成要素を有するナノキャリア
|
|
US8574835B2
(en)
|
2009-05-29 |
2013-11-05 |
Life Technologies Corporation |
Scaffolded nucleic acid polymer particles and methods of making and using
|
|
EP2440556A1
(en)
|
2009-06-10 |
2012-04-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of phosphatidylinositol 3-kinase
|
|
HRP20211619T1
(hr)
|
2009-06-10 |
2022-02-04 |
Arbutus Biopharma Corporation |
Poboljšana formulacija lipida
|
|
NZ597504A
(en)
|
2009-06-15 |
2013-10-25 |
Alnylam Pharmaceuticals Inc |
Lipid formulated dsrna targeting the pcsk9 gene
|
|
US20110097329A1
(en)
|
2009-06-26 |
2011-04-28 |
Massachusetts Institute Of Technology |
Compositions and methods for treating cancer and modulating stress granule formation
|
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
|
CA2767225A1
(en)
*
|
2009-07-06 |
2011-01-13 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for enhancing production of a biological product
|
|
WO2011005799A2
(en)
|
2009-07-06 |
2011-01-13 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
|
ES2587963T3
(es)
*
|
2009-07-31 |
2016-10-27 |
Ethris Gmbh |
ARN con una combinación de nucleótidos no modificados y modificados para la expresión de proteínas
|
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
|
US9181295B2
(en)
|
2009-08-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
Cationic lipids with various head groups for oligonucleotide delivery
|
|
WO2011028175A1
(en)
|
2009-09-01 |
2011-03-10 |
Agency For Science, Technology And Research |
Terminal device and method for processing an encrypted bit stream
|
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
|
US20110070227A1
(en)
|
2009-09-18 |
2011-03-24 |
Anna-Marie Novotney-Barry |
Treatment of Autoimmune and Inflammatory Diseases
|
|
EP2485770A4
(en)
|
2009-10-08 |
2013-04-10 |
Merck Sharp & Dohme |
Novel cationic lipids with short lipid chains for oligonucleotide delivery
|
|
US8859284B2
(en)
|
2009-10-22 |
2014-10-14 |
The United States Of America, As Represented By The Secretary Of The Navy |
Delivery of nanoparticles to neurons
|
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
|
WO2011060250A1
(en)
|
2009-11-13 |
2011-05-19 |
Bend Research, Inc. |
Cationic dextran polymer derivatives
|
|
WO2011062965A2
(en)
|
2009-11-18 |
2011-05-26 |
University Of Washington Through Its Center For Commercialization |
Targeting monomers and polymers having targeting blocks
|
|
US8530429B2
(en)
|
2009-11-24 |
2013-09-10 |
Arch Cancer Therapeutics, Inc. |
Brain tumor targeting peptides and methods
|
|
DK3338765T3
(en)
|
2009-12-01 |
2019-03-04 |
Translate Bio Inc |
STEROID DERIVATIVE FOR THE SUPPLY OF MRNA IN HUMANGENETIC DISEASES
|
|
DE102009056884B4
(de)
|
2009-12-03 |
2021-03-18 |
Novartis Ag |
Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
|
|
US20110245756A1
(en)
|
2009-12-03 |
2011-10-06 |
Rishi Arora |
Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
|
|
ME02964B
(me)
|
2009-12-06 |
2018-07-20 |
|
Himerni i hibridni polipeptidi faktora viii-fc, i postupci za njihovu upotrebu
|
|
US20130189741A1
(en)
|
2009-12-07 |
2013-07-25 |
Cellscript, Inc. |
Compositions and methods for reprogramming mammalian cells
|
|
LT3112467T
(lt)
|
2009-12-07 |
2018-06-25 |
The Trustees Of The University Of Pennsylvania |
Išgrynintą modifikuotą rnr apimantys rnr preparatai, skirti ląstelių perprogramavimui
|
|
WO2011071860A2
(en)
|
2009-12-07 |
2011-06-16 |
Alnylam Pharmaceuticals, Inc. |
Compositions for nucleic acid delivery
|
|
WO2011069528A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Lyophilization of nucleic acids in lactate-containing solutions
|
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
|
CN102811743B
(zh)
|
2009-12-11 |
2015-11-25 |
佰恩德治疗股份有限公司 |
冻干治疗颗粒的稳定制剂
|
|
WO2011084521A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticles comprising epothilone and methods of making and using same
|
|
WO2011084518A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticles comprising corticosteroids and methods of making and using same
|
|
EA201290499A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Композиции терапевтических полимерных наночастиц с высокой температурой стеклования и высокомолекулярными сополимерами
|
|
IN2012DN05099A
(OSRAM)
|
2009-12-16 |
2015-10-09 |
Brigham & Womens Hospital |
|
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
|
EP3494963A1
(en)
|
2009-12-18 |
2019-06-12 |
The University of British Columbia |
Methods and compositions for delivery of nucleic acids
|
|
EP2338520A1
(de)
|
2009-12-21 |
2011-06-29 |
Ludwig Maximilians Universität |
Konjugat mit Zielfindungsligand und dessen Verwendung
|
|
SG181904A1
(en)
|
2009-12-23 |
2012-07-30 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
|
WO2011076142A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expession profiling in plasma of colorectal cancer
|
|
WO2011076143A1
(en)
|
2009-12-24 |
2011-06-30 |
Fudan University |
Compositions and methods for microrna expression profiling of lung cancer
|
|
EP2341145A1
(en)
|
2009-12-30 |
2011-07-06 |
febit holding GmbH |
miRNA fingerprint in the diagnosis of diseases
|
|
US20110171248A1
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
WO2011088309A1
(en)
|
2010-01-14 |
2011-07-21 |
Regulus Therapeutics Inc. |
Microrna compositions and methods
|
|
EP2525781A1
(en)
|
2010-01-22 |
2012-11-28 |
Schering Corporation |
Novel cationic lipids for oligonucleotide delivery
|
|
WO2011094683A2
(en)
|
2010-01-29 |
2011-08-04 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Method of identifying myelodysplastic syndromes
|
|
EP2354246A1
(en)
|
2010-02-05 |
2011-08-10 |
febit holding GmbH |
miRNA in the diagnosis of ovarian cancer
|
|
NZ601737A
(en)
|
2010-02-24 |
2013-06-28 |
Arrowhead Res Corp |
Compositions for targeted delivery of sirna
|
|
WO2011106702A2
(en)
|
2010-02-25 |
2011-09-01 |
The Johns Hopkins University |
Sustained delivery of therapeutic agents to an eye compartment
|
|
WO2011112608A1
(en)
|
2010-03-08 |
2011-09-15 |
University Of Rochester |
Synthesis of nanoparticles using reducing gases
|
|
WO2011113030A2
(en)
|
2010-03-11 |
2011-09-15 |
H.Lee Moffitt Cancer Center & Research Institute |
Human cancer micro-rna expression profiles predictive of chemo-response
|
|
WO2011116072A1
(en)
|
2010-03-16 |
2011-09-22 |
Escape Therapeutics, Inc. |
Hybrid hydrogel scaffold compositions and methods of use
|
|
KR20130006663A
(ko)
|
2010-03-16 |
2013-01-17 |
유니버시티 오브 유타 리서치 파운데이션 |
뉴클레오티드 전달을 높이기 위한 환원가능한 폴리(아미도 에틸렌이민)으로의 절단성 변형법
|
|
US20110230816A1
(en)
|
2010-03-18 |
2011-09-22 |
Tyco Healthcare Group Lp |
Gels for Transdermal Delivery
|
|
WO2011115862A1
(en)
|
2010-03-18 |
2011-09-22 |
Merck Sharp & Dohme Corp. |
Endosomolytic poly(amidoamine) disulfide polymers for the delivery of oligonucleotides
|
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
|
GB201005005D0
(en)
|
2010-03-25 |
2010-05-12 |
Angeletti P Ist Richerche Bio |
New vaccine
|
|
US8349308B2
(en)
|
2010-03-26 |
2013-01-08 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
|
US20110247090A1
(en)
|
2010-04-02 |
2011-10-06 |
Intrexon Corporation |
Synthetic 5'UTRs, Expression Vectors, and Methods for Increasing Transgene Expression
|
|
EP2555794A4
(en)
|
2010-04-05 |
2014-01-15 |
Univ Chicago |
COMPOSITIONS AND METHODS RELATING TO PROTEIN A (SPA) ANTIBODIES AS IMMUNE REACTION AMPLIFIERS
|
|
WO2011127316A1
(en)
|
2010-04-07 |
2011-10-13 |
Novartis Ag |
Method for generating a parvovirus b19 virus-like particle
|
|
US20130037977A1
(en)
|
2010-04-08 |
2013-02-14 |
Paul A. Burke |
Preparation of Lipid Nanoparticles
|
|
JP6043278B2
(ja)
|
2010-04-09 |
2016-12-14 |
パシラ ファーマシューティカルズ インコーポレーテッド |
多小胞リポソームを作製するための方法、大直径合成膜小胞を調製するための方法、および蒸発装置
|
|
JP5652830B2
(ja)
|
2010-04-09 |
2015-01-14 |
国立大学法人 東京大学 |
マイクロｒｎａ制御組換えワクシニアウイルス及びその使用
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
KR101196667B1
(ko)
|
2010-04-15 |
2012-11-02 |
포항공과대학교 산학협력단 |
피에이치 민감성 금속 나노 입자를 이용한 항암제 전달 시스템
|
|
CA2796464C
(en)
|
2010-04-16 |
2021-08-03 |
Immune Disease Institute, Inc. |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
EP2558577B1
(en)
|
2010-04-16 |
2018-12-12 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
|
EP2377938A1
(en)
|
2010-04-16 |
2011-10-19 |
Eukarys |
Capping-prone RNA polymerase enzymes and their applications
|
|
WO2011133868A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
|
DK2826860T3
(en)
*
|
2010-04-23 |
2018-12-03 |
Univ Massachusetts |
CNS targeting AAV vectors and methods for their use
|
|
US9629979B2
(en)
|
2010-04-28 |
2017-04-25 |
Sanovas, Inc. |
Pressure/Vacuum actuated catheter drug delivery probe
|
|
EP2563455A4
(en)
|
2010-04-28 |
2014-02-19 |
Kimberly Clark Co |
METHOD FOR INCREASING THE PERMEABILITY OF AN EPITHELIAL BARRIER
|
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
|
MX2012012615A
(es)
|
2010-04-30 |
2012-12-17 |
Novartis Ag |
Marcadores predictivos utiles en el tratamiento del sindrome fragil x (fxs).
|
|
WO2011143230A1
(en)
|
2010-05-10 |
2011-11-17 |
Alnylam Pharmaceuticals |
Methods and compositions for delivery of active agents
|
|
US10077232B2
(en)
|
2010-05-12 |
2018-09-18 |
Arbutus Biopharma Corporation |
Cyclic cationic lipids and methods of use
|
|
EP2569276B1
(en)
|
2010-05-12 |
2021-02-24 |
Arbutus Biopharma Corporation |
Novel cationic lipids and methods of use thereof
|
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
|
NO2575876T3
(OSRAM)
|
2010-05-26 |
2018-05-05 |
|
|
|
DK2575767T3
(en)
|
2010-06-04 |
2017-03-13 |
Sirna Therapeutics Inc |
HOWEVER UNKNOWN LOW MOLECULAR CATIONIC LIPIDS TO PROCESS OIGONUCLEOTIDES
|
|
AU2011267078B2
(en)
|
2010-06-14 |
2014-09-25 |
F. Hoffmann-La Roche Ag |
Cell-penetrating peptides and uses therof
|
|
WO2011157294A1
(en)
|
2010-06-16 |
2011-12-22 |
Universita' Degli Studi Di Padova |
Compositions for use in treating or preventing cancer, breast cancer, lung cancer, ovarian cancer, metastasis, heart failure, cardiac remodelling, dilated cardiomyopathy, autoimmune diseases, or diseases or disorders related thereto
|
|
US20130236968A1
(en)
|
2010-06-21 |
2013-09-12 |
Alnylam Pharmaceuticals, Inc. |
Multifunctional copolymers for nucleic acid delivery
|
|
WO2011163264A2
(en)
|
2010-06-21 |
2011-12-29 |
Candela Corporation |
Driving microneedle arrays into skin and delivering rf energy
|
|
EP2585106A1
(en)
|
2010-06-25 |
2013-05-01 |
Novartis AG |
Combinations of meningococcal factor h binding proteins
|
|
WO2012002760A2
(ko)
|
2010-07-01 |
2012-01-05 |
포항공과대학교 산학협력단 |
세균유래 마이크로베시클을 이용한 암치료 및 암진단 방법
|
|
KR101130137B1
(ko)
|
2010-07-02 |
2012-03-28 |
연세대학교 산학협력단 |
발광다이오드 모듈
|
|
SG186290A1
(en)
|
2010-07-02 |
2013-01-30 |
Univ Chicago |
Compositions and methods related to protein a (spa) variants
|
|
US8353871B2
(en)
|
2010-07-05 |
2013-01-15 |
Roller Jet Ltd. |
Drug delivery device with needles and roller
|
|
WO2012006380A2
(en)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
PL2591114T3
(pl)
|
2010-07-06 |
2017-08-31 |
Glaxosmithkline Biologicals Sa |
Immunizacja dużych ssaków małymi dawkami rna
|
|
ES2557382T3
(es)
|
2010-07-06 |
2016-01-25 |
Glaxosmithkline Biologicals Sa |
Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN
|
|
FI4005592T3
(fi)
|
2010-07-06 |
2023-01-13 |
|
Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille
|
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
PL3243526T3
(pl)
|
2010-07-06 |
2020-05-18 |
Glaxosmithkline Biologicals S.A. |
Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych
|
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
|
EP2591101B1
(en)
|
2010-07-09 |
2018-11-07 |
Bioverativ Therapeutics Inc. |
Systems for factor viii processing and methods thereof
|
|
AU2011274414B2
(en)
|
2010-07-09 |
2016-10-06 |
Bioverativ Therapeutics Inc. |
Factor IX polypeptides and methods of use thereof
|
|
US20130177523A1
(en)
|
2010-07-13 |
2013-07-11 |
University Of Utah Research Foundation |
Gold particles and methods of making and using the same in cancer treatment
|
|
WO2012009644A2
(en)
|
2010-07-16 |
2012-01-19 |
Arizona Board Of Regents |
Methods to identify synthetic and natural rna elements that enhance protein translation
|
|
GB201012410D0
(en)
|
2010-07-23 |
2010-09-08 |
Medical Res Council |
Intracellular immunity
|
|
BR112013002298A2
(pt)
|
2010-07-30 |
2016-05-24 |
Curevac Gmbh |
complexação de ácidos nucleicos com componentes catiônicos reticulados com dissulfeto para transfecção e estimulação imunológica.
|
|
EP3578205A1
(en)
|
2010-08-06 |
2019-12-11 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
|
WO2012021516A2
(en)
|
2010-08-09 |
2012-02-16 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucletide hybrid structures and methods of use thereof
|
|
WO2012019630A1
(en)
*
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
|
CA2808965C
(en)
|
2010-08-20 |
2020-01-07 |
Novartis Ag |
Soluble needle arrays for delivery of influenza vaccines
|
|
MX2013002048A
(es)
|
2010-08-20 |
2013-07-03 |
Cerulean Pharma Inc |
Conjugados, particulas, composiciones y metodos relacionados.
|
|
US20130142868A1
(en)
|
2010-08-20 |
2013-06-06 |
University Of Washington |
Circumferential Aerosol Device for Delivering Drugs to Olfactory Epithelium and Brain
|
|
WO2012024621A2
(en)
|
2010-08-20 |
2012-02-23 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza a virus hemagglutinin
|
|
EP3406730B1
(en)
|
2010-08-31 |
2022-02-23 |
Sirna Therapeutics, Inc. |
Novel single chemical entities and methods for delivery of oligonucleotides
|
|
HUE061068T2
(hu)
|
2010-08-31 |
2023-05-28 |
Glaxosmithkline Biologicals Sa |
Pegilált liposzómák immunogént kódoló RNS szállítására
|
|
EP2611465A4
(en)
|
2010-08-31 |
2014-06-04 |
Theraclone Sciences Inc |
ANTIBODIES FOR NEUTRALIZING THE HUMAN IMMUNODICITY VIRUS (HIV)
|
|
MX341989B
(es)
|
2010-08-31 |
2016-09-09 |
Novartis Ag * |
Liposomas pequeños para el suministro de arn que codifica el inmunogeno.
|
|
EP3542789A3
(en)
|
2010-08-31 |
2020-01-01 |
GlaxoSmithKline Biologicals SA |
Lipids suitable for liposomal delivery of protein-coding rna
|
|
US9549901B2
(en)
|
2010-09-03 |
2017-01-24 |
The Brigham And Women's Hospital, Inc. |
Lipid-polymer hybrid particles
|
|
EP2614074A1
(en)
|
2010-09-09 |
2013-07-17 |
The University of Chicago |
Methods and compositions involving protective staphylococcal antigens
|
|
US20130236419A1
(en)
|
2010-09-09 |
2013-09-12 |
The University Of Chicago |
Compositions and methods related to attenuated staphylococcal strains
|
|
WO2012039979A2
(en)
|
2010-09-10 |
2012-03-29 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
|
BR112013004585B1
(pt)
|
2010-09-20 |
2021-09-08 |
Merck Sharp & Dohme Corp |
Lipídeo catiônico, composição de lnp, e, uso de um lipídeo catiônico
|
|
WO2012038448A1
(en)
|
2010-09-21 |
2012-03-29 |
Riboxx Gmbh |
Method for synthesizing rna using dna template
|
|
JP2013540757A
(ja)
|
2010-09-24 |
2013-11-07 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド |
カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル
|
|
WO2012050975A2
(en)
|
2010-09-29 |
2012-04-19 |
The University Of North Carolina At Chapel Hill |
Novel circular mammalian rna molecules and uses thereof
|
|
JP2013545723A
(ja)
|
2010-09-30 |
2013-12-26 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチドの送達のための低分子量カチオン性脂質
|
|
CN103429606A
(zh)
|
2010-10-01 |
2013-12-04 |
现代治疗公司 |
设计核酸及其使用方法
|
|
US10078075B2
(en)
|
2011-12-09 |
2018-09-18 |
Vanderbilt University |
Integrated organ-on-chip systems and applications of the same
|
|
EP4098324A1
(en)
|
2010-10-11 |
2022-12-07 |
GlaxoSmithKline Biologicals S.A. |
Antigen delivery platforms
|
|
EP2629802B1
(en)
|
2010-10-21 |
2019-12-04 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
|
JP2013543844A
(ja)
|
2010-10-22 |
2013-12-09 |
バインド セラピューティックス インコーポレイテッド |
高分子コポリマーを含む治療用ナノ粒子
|
|
SG10201801947YA
(en)
|
2010-10-29 |
2018-04-27 |
Merck Sharp & Dohme |
Recombinant subunit dengue virus vaccine
|
|
CA3054532C
(en)
|
2010-11-05 |
2022-07-12 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
|
WO2012061259A2
(en)
|
2010-11-05 |
2012-05-10 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery
|
|
AU2011326732B2
(en)
|
2010-11-09 |
2016-07-21 |
The Regents Of The University Of California |
Skin permeating and cell entering (space) peptides and methods of use thereof
|
|
KR101939150B1
(ko)
|
2010-11-12 |
2019-01-17 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
공통 전립선 항원, 이것을 암호화하는 핵산 분자, 그리고 이것을 포함하는 백신 및 용도
|
|
BR112013012195A2
(pt)
|
2010-11-16 |
2018-07-10 |
Selecta Biosciences Inc |
oligonucleotídeo imunoestimulatórios
|
|
SI2640842T1
(sl)
|
2010-11-17 |
2018-09-28 |
Aduro Biotech, Inc. |
Postopki in sestavki za induciranje imunskega odziva na EGFRvIII
|
|
EP3213770B1
(en)
|
2010-11-19 |
2021-02-24 |
Idera Pharmaceuticals, Inc. |
Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
|
|
WO2012068187A1
(en)
|
2010-11-19 |
2012-05-24 |
Merck Sharp & Dohme Corp. |
Poly(amide) polymers for the delivery of oligonucleotides
|
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
|
WO2012072096A1
(en)
|
2010-12-03 |
2012-06-07 |
Biontech Ag |
Method for cellular rna expression
|
|
AU2011358150B2
(en)
|
2010-12-16 |
2016-11-03 |
Sprna Gmbh |
Pharmaceutical composition consisting of RNA having alkali metal as counter ion and formulated with dications
|
|
WO2012082574A1
(en)
|
2010-12-17 |
2012-06-21 |
Merck Sharp & Dohme Corp. |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides
|
|
US8501930B2
(en)
|
2010-12-17 |
2013-08-06 |
Arrowhead Madison Inc. |
Peptide-based in vivo siRNA delivery system
|
|
AU2011348204B2
(en)
|
2010-12-22 |
2017-03-02 |
President And Fellows Of Harvard College |
Continuous directed evolution
|
|
BR122020024394B1
(pt)
|
2010-12-29 |
2021-05-11 |
F. Hoffmann-La Roche Ag |
conjugado e composição farmacêutica
|
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
EP2661255B1
(en)
|
2011-01-04 |
2021-03-10 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
|
WO2012094574A2
(en)
|
2011-01-06 |
2012-07-12 |
The Johns Hopkins University |
Stabilized polyribonucleotide nanoparticles
|
|
WO2012094653A2
(en)
|
2011-01-07 |
2012-07-12 |
Massachusetts Institute Of Technology |
Compositions and methods for macromolecular drug delivery
|
|
DK3202760T3
(da)
|
2011-01-11 |
2019-11-25 |
Alnylam Pharmaceuticals Inc |
Pegylerede lipider og deres anvendelse til lægemiddelfremføring
|
|
DE102011082231A1
(de)
|
2011-01-12 |
2012-07-12 |
Robert Bosch Gmbh |
Zündspule, insbesondere für kleinbauende Motoren
|
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
|
JP2014505064A
(ja)
|
2011-01-26 |
2014-02-27 |
セニックス バイオサイエンス ゲーエムベーハー |
自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート
|
|
US10363309B2
(en)
|
2011-02-04 |
2019-07-30 |
Case Western Reserve University |
Targeted nanoparticle conjugates
|
|
WO2012109121A1
(en)
|
2011-02-07 |
2012-08-16 |
Purdue Research Foundation |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
|
US20120207840A1
(en)
|
2011-02-10 |
2012-08-16 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
|
|
JP2014507149A
(ja)
|
2011-02-14 |
2014-03-27 |
スウィフト バイオサイエンシーズ， インコーポレイテッド |
ポリヌクレオチドプライマーおよびプローブ
|
|
WO2012112689A1
(en)
|
2011-02-15 |
2012-08-23 |
The University Of North Carolina At Chapel Hill |
Nanoparticle, liposomes, polymers, agents and proteins modified with reversible linkers
|
|
CA2827118A1
(en)
|
2011-02-15 |
2012-08-23 |
Merrimack Pharmaceuticals, Inc. |
Compositions and methods for delivering nucleic acid to a cell
|
|
EP2489371A1
(en)
|
2011-02-18 |
2012-08-22 |
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria |
Carrier peptides for drug delivery
|
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
|
EP2678433B1
(en)
|
2011-02-22 |
2017-05-03 |
California Institute of Technology |
Delivery of proteins using adeno-associated virus (aav) vectors
|
|
US8696637B2
(en)
|
2011-02-28 |
2014-04-15 |
Kimberly-Clark Worldwide |
Transdermal patch containing microneedles
|
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
|
WO2012117377A1
(en)
|
2011-03-02 |
2012-09-07 |
Novartis Ag |
Combination vaccines with lower doses of antigen and/or adjuvant
|
|
CA2832807A1
(en)
|
2011-03-07 |
2012-09-13 |
Massachusetts Institute Of Technology |
Methods for transfecting cells with nucleic acids
|
|
WO2012125680A1
(en)
|
2011-03-16 |
2012-09-20 |
Novartis Ag |
Methods of treating vasculitis using an il-17 binding molecule
|
|
US20140212503A1
(en)
|
2011-03-17 |
2014-07-31 |
Hyukjin Lee |
Delivery system
|
|
AU2012229107A1
(en)
|
2011-03-17 |
2013-09-19 |
Novartis Ag |
FGFR and ligands thereof as biomarkers for breast cancer in HR positive subjects
|
|
EP2688590B1
(en)
|
2011-03-24 |
2020-02-12 |
GlaxoSmithKline Biologicals SA |
Adjuvant nanoemulsions with phospholipids
|
|
US20140005070A1
(en)
|
2011-03-28 |
2014-01-02 |
Novartis Ag |
Markers associated with cyclin-dependent kinase inhibitors
|
|
US9238716B2
(en)
|
2011-03-28 |
2016-01-19 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
CA2831613A1
(en)
|
2011-03-31 |
2012-10-04 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
US10086043B2
(en)
*
|
2011-04-03 |
2018-10-02 |
The General Hospital Corporation |
Efficient protein expression in vivo using modified RNA (MOD-RNA)
|
|
ES2587512T3
(es)
|
2011-04-04 |
2016-10-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Derivados de 2'-O-aminooximetil nucleósido para su uso en la síntesis y modificación de nucleósidos, nucleótidos y oligonucleótidos
|
|
WO2012142132A1
(en)
|
2011-04-11 |
2012-10-18 |
Life Technologies Corporation |
Polymer particles and methods of making and using same
|
|
WO2012142240A1
(en)
|
2011-04-13 |
2012-10-18 |
The Trustees Of The University Of Pennsylvania |
Coated mesoporous nanoparticles
|
|
WO2013158127A1
(en)
|
2012-04-16 |
2013-10-24 |
Molecular Transfer, Inc. |
Agents for improved delivery of nucleic acids to eukaryotic cells
|
|
US20140178894A1
(en)
|
2011-04-20 |
2014-06-26 |
Novartis Forschungsstiftung, Zweigniederlassung |
Culture medium suitable for the culture of undifferentiated cells
|
|
WO2012149045A2
(en)
|
2011-04-26 |
2012-11-01 |
Molecular Express, Inc. |
Liposomal formulations
|
|
JP2014512409A
(ja)
|
2011-04-28 |
2014-05-22 |
エスティーシー． ユーエヌエム |
標的送達用の多孔性ナノ粒子に担持された脂質二重層（プロトセル）及びその使用方法
|
|
US20160272697A2
(en)
|
2011-04-28 |
2016-09-22 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Neutralizing Antibodies to Nipah and Hendra Virus
|
|
US20140056912A1
(en)
|
2011-04-29 |
2014-02-27 |
Novartis Ag |
Methods of treating squamous cell carcinoma
|
|
CN103501812A
(zh)
|
2011-04-29 |
2014-01-08 |
西莱克塔生物科技公司 |
用于过敏症治疗的致耐受性合成纳米载体
|
|
WO2012151212A1
(en)
|
2011-05-01 |
2012-11-08 |
University Of Rochester |
Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof
|
|
EP3777538B1
(en)
|
2011-05-02 |
2023-06-28 |
Wayne State University |
A protein-induced pluripotent cell technology and uses thereof
|
|
UA116189C2
(uk)
|
2011-05-02 |
2018-02-26 |
Мілленніум Фармасьютікалз, Інк. |
КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
|
|
US8945588B2
(en)
|
2011-05-06 |
2015-02-03 |
The University Of Chicago |
Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
|
|
CA2835179A1
(en)
|
2011-05-06 |
2012-11-15 |
Xentech |
Markers for cancer prognosis and therapy and methods of use
|
|
CN103547350A
(zh)
|
2011-05-10 |
2014-01-29 |
巴斯夫欧洲公司 |
水包油乳液
|
|
CN103687624B
(zh)
|
2011-05-11 |
2018-02-02 |
雷蒙特亚特特拉维夫大学有限公司 |
靶向的聚合缀合物和其用途
|
|
WO2012152910A1
(en)
|
2011-05-12 |
2012-11-15 |
Helmut Vockner |
Novel pharmaceutical formulation
|
|
JP2014519493A
(ja)
|
2011-05-12 |
2014-08-14 |
イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド |
ポリマー共役脂質を含むリポソームおよび関連用途
|
|
BR112013029169B1
(pt)
|
2011-05-13 |
2021-09-28 |
Novartis Ag |
Polipeptídeo f pré-fusão do vírus sincicial respiratório (rsv), composição imunogênica e uso da mesma
|
|
JP2014520084A
(ja)
|
2011-05-17 |
2014-08-21 |
モデルナ セラピューティクス インコーポレイテッド |
非ヒト脊椎動物用の改変核酸及びその使用方法
|
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
|
US8978170B2
(en)
|
2011-05-20 |
2015-03-17 |
Kohler Co. |
Toilet installation system and method
|
|
LT3892295T
(lt)
|
2011-05-24 |
2023-07-10 |
BioNTech SE |
Individualizuotos vakcinos nuo vėžio
|
|
WO2012160177A1
(en)
|
2011-05-25 |
2012-11-29 |
Novartis Ag |
Biomarkers for lung cancer
|
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
|
EP3412282B1
(en)
|
2011-06-02 |
2024-10-09 |
The Regents of the University of California |
Membrane encapsulated nanoparticles and method of use
|
|
WO2012166241A1
(en)
|
2011-06-02 |
2012-12-06 |
Novartis Ag |
Biomarkers for hedgehog inhibitor therapy
|
|
EP2717911A1
(en)
|
2011-06-06 |
2014-04-16 |
Novartis Forschungsstiftung, Zweigniederlassung |
Protein tyrosine phosphatase, non-receptor type 11 (ptpn11) and triple-negative breast cancer
|
|
JP6184945B2
(ja)
|
2011-06-08 |
2017-08-23 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
ｍＲＮＡ送達のための脂質ナノ粒子組成物および方法
|
|
ES2987057T3
(es)
|
2011-06-08 |
2024-11-13 |
Translate Bio Inc |
Lípidos escindibles
|
|
US8636696B2
(en)
|
2011-06-10 |
2014-01-28 |
Kimberly-Clark Worldwide, Inc. |
Transdermal device containing microneedles
|
|
WO2012170607A2
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Use of pcsk9 antagonists
|
|
CA2836805C
(en)
|
2011-06-10 |
2023-03-07 |
Novartis Ag |
Bovine vaccines and methods
|
|
WO2012168491A1
(en)
|
2011-06-10 |
2012-12-13 |
Novartis Ag |
Pharmaceutical formulations of pcsk9 antagonists
|
|
US8916696B2
(en)
|
2011-06-12 |
2014-12-23 |
City Of Hope |
Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
|
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
|
EP2720740A1
(en)
|
2011-06-15 |
2014-04-23 |
ChronTech Pharma AB |
Injection needle and device
|
|
US20140193408A1
(en)
|
2011-06-16 |
2014-07-10 |
Novartis Ag |
Soluble proteins for use as therapeutics
|
|
RU2612900C2
(ru)
|
2011-06-20 |
2017-03-13 |
Юниверсити Оф Питтсбург - Оф Зе Коммонвэлс Систем Оф Хайе Эдьюкейшн |
Антигены вируса гриппа h1n1 с широким спектром активности, оптимизированные с применением вычислительных средств
|
|
US9862926B2
(en)
|
2011-06-27 |
2018-01-09 |
Cellscript, Llc. |
Inhibition of innate immune response
|
|
CN103687644B
(zh)
|
2011-06-28 |
2016-11-09 |
艾诺奥医药品有限公司 |
微创性皮肤电穿孔装置
|
|
DK2726099T3
(en)
|
2011-07-01 |
2018-11-05 |
Novartis Ag |
Method of treating metabolic disorders
|
|
EP2729182A4
(en)
|
2011-07-04 |
2014-12-24 |
Commw Scient Ind Res Org |
NUCLEIC COMPLEX
|
|
CA2840989A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic combination compositions and uses thereof
|
|
EP4115875A1
(en)
|
2011-07-06 |
2023-01-11 |
GlaxoSmithKline Biologicals S.A. |
Liposomes having useful n:p ratio for delivery of rna molecules
|
|
CA2841047A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
|
SG10201605512WA
(en)
|
2011-07-06 |
2016-09-29 |
Novartis Ag |
Oil-in-water emulsions that contain nucleic acids
|
|
BR112014000235A8
(pt)
|
2011-07-06 |
2018-03-06 |
Novartis Ag |
emulsões de óleo em água catiônicas
|
|
WO2013006824A2
(en)
|
2011-07-07 |
2013-01-10 |
Life Technologies Corporation |
Polymer particles, nucleic acid polymer particles and methods of making and using the same
|
|
EP2758458A4
(en)
|
2011-07-10 |
2015-10-21 |
Harvard College |
COMPOSITIONS AND METHODS FOR SELF-ASSEMBLING POLYMERS WITH COMPLEMENTARY MACROSCOPIC AND MICROSCOPIC SCALE UNITS
|
|
WO2013009717A1
(en)
|
2011-07-10 |
2013-01-17 |
Elisabet De Los Pinos |
Virion derived protein nanoparticles for delivering diagnostic or therapeutic agents for the treatment of skin-related diseases
|
|
US20130012566A1
(en)
|
2011-07-10 |
2013-01-10 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia
|
|
DK2732052T3
(en)
|
2011-07-15 |
2017-02-20 |
Leo Pharma As |
Diagnostic microRNA profiling in cutaneous T cell lymphoma (CTCL)
|
|
GB2492999A
(en)
|
2011-07-20 |
2013-01-23 |
Univ Central Lancashire |
Neutron detector
|
|
US20140148503A1
(en)
|
2011-07-20 |
2014-05-29 |
University Of Iowa Research Foundation |
Nucleic acid aptamers
|
|
ES2670944T3
(es)
|
2011-07-21 |
2018-06-04 |
Croda International Plc |
Copolímeros de bloques de poliéter-poliamida ramificados y métodos de preparación y uso de los mismos
|
|
WO2013016460A1
(en)
|
2011-07-25 |
2013-01-31 |
Novartis Ag |
Compositions and methods for assessing functional immunogenicity of parvovirus vaccines
|
|
US9493549B2
(en)
|
2011-07-25 |
2016-11-15 |
The Rockefeller University |
Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
|
|
US20130039954A1
(en)
|
2011-07-29 |
2013-02-14 |
Selecta Biosciences, Inc. |
Control of antibody responses to synthetic nanocarriers
|
|
BR112014003315A2
(pt)
|
2011-08-15 |
2017-03-01 |
Univ Chicago |
composições e métodos relacionados a anticorpos para a proteína a estafilocócica
|
|
JP2014531476A
(ja)
|
2011-08-26 |
2014-11-27 |
アローヘッド リサーチ コーポレイション |
インビボ核酸送達のためのポリ（ビニルエステル）ポリマー
|
|
EP2750707B1
(en)
|
2011-08-31 |
2018-10-24 |
GlaxoSmithKline Biologicals SA |
Pegylated liposomes for delivery of immunogen-encoding rna
|
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
|
KR20140067070A
(ko)
|
2011-08-31 |
2014-06-03 |
말린크로트 엘엘씨 |
Ｈ-포스포네이트에 의한 나노입자 ｐｅｇ 개질
|
|
CN104039783A
(zh)
|
2011-09-01 |
2014-09-10 |
Irm责任有限公司 |
作为pdgfr激酶抑制剂的化合物和组合物
|
|
WO2013033640A1
(en)
|
2011-09-01 |
2013-03-07 |
Allegro Diagnostics Corp. |
Methods and compositions for detecting cancer based on mirna expression profiles
|
|
CN103930547A
(zh)
|
2011-09-02 |
2014-07-16 |
诺华股份有限公司 |
用于治疗hsf1相关疾病的有机组合物
|
|
WO2013039857A1
(en)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Engineered nucleic acids and methods of use thereof
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2755693A4
(en)
|
2011-09-12 |
2015-05-20 |
Moderna Therapeutics Inc |
MANIPULATED NUCLEIC ACIDS AND METHOD OF APPLICATION THEREFOR
|
|
US9358284B2
(en)
|
2011-09-14 |
2016-06-07 |
Glaxosmithkline Biologicals Sa |
Methods for making saccharide-protein glycoconjugates
|
|
WO2013040557A2
(en)
|
2011-09-16 |
2013-03-21 |
The Trustees Of The University Of Pennsylvania |
Rna engineered t cells for the treatment of cancer
|
|
US20150017245A1
(en)
|
2011-09-22 |
2015-01-15 |
Bind Therapeutics, Inc. |
Methods of treating cancers with therapeutic nanoparticles
|
|
US9375388B2
(en)
|
2011-09-23 |
2016-06-28 |
Indian Institute Of Technology, Bombay |
Nanoparticle based cosmetic composition
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
US9006400B2
(en)
|
2011-09-26 |
2015-04-14 |
Novartis Ag |
Fibroblast growth factor-21-Fc fusion proteins
|
|
AU2012315965A1
(en)
|
2011-09-27 |
2014-04-03 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted PEGylated lipids
|
|
WO2013045505A1
(en)
|
2011-09-28 |
2013-04-04 |
Novartis Ag |
Biomarkers for raas combination therapy
|
|
KR20190099538A
(ko)
|
2011-10-03 |
2019-08-27 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도
|
|
WO2013055971A1
(en)
|
2011-10-11 |
2013-04-18 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Polymers for delivering a substance into a cell
|
|
MX2014004214A
(es)
|
2011-10-11 |
2014-05-07 |
Novartis Ag |
Moleculas de acido ribonucleico policistronicas auto-replicantes recombinantes.
|
|
WO2013055331A1
(en)
|
2011-10-12 |
2013-04-18 |
The Curators Of The University Of Missouri |
Pentablock polymers
|
|
WO2014066811A1
(en)
|
2012-10-25 |
2014-05-01 |
The Johns Hopkins University |
Bioreducible poly (b-amino ester)s for sirna delivery
|
|
WO2013056132A2
(en)
|
2011-10-14 |
2013-04-18 |
Stc.Unm |
Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery including transdermal delivery of cargo and methods thereof
|
|
EP3653222A1
(en)
|
2011-10-14 |
2020-05-20 |
Novartis AG |
Antibodies and methods for wnt pathway-related diseases
|
|
US20140371717A1
(en)
|
2011-10-18 |
2014-12-18 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2768958B1
(en)
|
2011-10-18 |
2019-08-14 |
Dicerna Pharmaceuticals, Inc. |
Amine cationic lipids and uses thereof
|
|
AU2012324458B2
(en)
|
2011-10-20 |
2016-05-19 |
Novartis Ag |
Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
|
|
US20140248320A1
(en)
|
2011-10-20 |
2014-09-04 |
Novartis Ag |
Adjuvanted influenza b virus vaccines for pediatric priming
|
|
EP2770980A4
(en)
|
2011-10-25 |
2015-11-04 |
Univ British Columbia |
LOW SIZE LIPID NANOPARTICLES AND METHODS THEREOF
|
|
US20130110043A1
(en)
|
2011-10-26 |
2013-05-02 |
Nanopass Technologies Ltd. |
Microneedle Intradermal Drug Delivery Device with Auto-Disable Functionality
|
|
US20140243240A1
(en)
|
2011-10-26 |
2014-08-28 |
Georgetown University |
microRNA EXPRESSION PROFILING OF THYROID CANCER
|
|
EP3574950B1
(en)
|
2011-10-27 |
2021-02-17 |
Sorrento Therapeutics, Inc. |
Transdermal delivery of high viscosity bioactive agents
|
|
EA032088B1
(ru)
|
2011-10-27 |
2019-04-30 |
Массачусетс Инститьют Оф Текнолоджи |
Аминокислотные производные, функционализованные на n-конце, способные образовывать микросферы, инкапсулирующие лекарственное средство
|
|
WO2013062140A1
(en)
|
2011-10-28 |
2013-05-02 |
Kyoto University |
Method for efficiently inducing differentiation of pluripotent stem cells into hepatic lineage cells
|
|
AU2012328457A1
(en)
|
2011-10-28 |
2014-04-24 |
Presage Biosciences, Inc. |
Methods for drug delivery
|
|
WO2013063510A1
(en)
|
2011-10-28 |
2013-05-02 |
Integritybio Inc. |
Protein formulations containing amino acids
|
|
WO2013066903A1
(en)
|
2011-10-31 |
2013-05-10 |
Mallinckrodt Llc |
Combinational liposome compositions for cancer therapy
|
|
EP2773662A4
(en)
|
2011-10-31 |
2015-07-01 |
Hoffmann La Roche |
ANTIBODY FORMULATIONS
|
|
CN103906503B
(zh)
|
2011-11-04 |
2016-12-14 |
日东电工株式会社 |
用于无菌制备脂质-核酸颗粒的单次使用系统
|
|
US9579338B2
(en)
|
2011-11-04 |
2017-02-28 |
Nitto Denko Corporation |
Method of producing lipid nanoparticles for drug delivery
|
|
EP3290442A1
(en)
|
2011-11-04 |
2018-03-07 |
Novartis AG |
Low density lipoprotein-related protein 6 (lrp6) half-life extender constructs
|
|
WO2013067537A1
(en)
|
2011-11-04 |
2013-05-10 |
Univertiy Of Notre Dame Du Lac |
Nanoparticle-based drug delivery
|
|
WO2013066274A1
(en)
|
2011-11-04 |
2013-05-10 |
Agency For Science, Technology And Research |
Self-assembled composite ultrasmall peptide-polymer hydrogels
|
|
US20130115247A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
|
US20130116408A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
|
US20140287510A1
(en)
|
2011-11-08 |
2014-09-25 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute |
Rod cell-specific promoter
|
|
EP2776013B8
(en)
|
2011-11-08 |
2023-08-30 |
The Board of Trustees of the University of Arkansas |
Methods and compositions for x-ray induced release from ph sensitive liposomes
|
|
EP2776022A1
(en)
|
2011-11-08 |
2014-09-17 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
New treatment for neurodegenerative diseases
|
|
WO2013068432A1
(en)
|
2011-11-08 |
2013-05-16 |
Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research |
Early diagnostic of neurodegenerative diseases
|
|
US9581590B2
(en)
|
2011-11-09 |
2017-02-28 |
Board Of Trustees Of Michigan State University |
Metallic nanoparticle synthesis with carbohydrate capping agent
|
|
DK2776567T3
(da)
|
2011-11-11 |
2021-04-26 |
Variation Biotechnologies Inc |
Sammensætninger og fremgangsmåder til behandling af cytomegalovirus.
|
|
WO2013071047A1
(en)
|
2011-11-11 |
2013-05-16 |
Children's Medical Center Corporation |
Compositions and methods for in vitro transcription of rna
|
|
RU2014124154A
(ru)
|
2011-11-14 |
2015-12-27 |
Новартис Аг |
Иммуногенные комплексы полианионных карбомеров и полипептидов env и способы их получения и применения
|
|
WO2013072392A1
(en)
|
2011-11-15 |
2013-05-23 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research |
Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2-signal transducer and activator of transcription 5 pathway
|
|
RU2768492C2
(ru)
|
2011-11-18 |
2022-03-24 |
Ридженерон Фармасьютикалз, Инк. |
Полимерные белковые микрочастицы
|
|
KR20140097178A
(ko)
|
2011-11-21 |
2014-08-06 |
노파르티스 아게 |
IL-17 길항제 및 건선성 관절염 (PsA) 반응 또는 비-반응 대립유전자를 이용하여 PsA를 치료하는 방법
|
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
|
TR201111743A2
(tr)
|
2011-11-28 |
2012-04-24 |
Nesl�Han G�Rsoy Reyhan |
Kanser tedavisinde kullanılmak üzere yağ bazlı nanotaşıyıcı sistemler.
|
|
EP2785326A2
(en)
|
2011-11-29 |
2014-10-08 |
The University of North Carolina at Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
|
BR112014013151B1
(pt)
|
2011-11-30 |
2022-02-08 |
3M Innovative Properties Company |
Dispositivo médico compreendendo microagulhas incluindo um agente terapêutico peptídeo e um aminoácido, métodos para produzir o dispositivo e método para estabilizar um agente terapêutico peptídeo
|
|
US9364549B2
(en)
|
2011-11-30 |
2016-06-14 |
Andreas Voigt |
Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
|
|
WO2013082590A1
(en)
|
2011-12-02 |
2013-06-06 |
Invivo Therapeutics Corporation |
Peg based hydrogel for peripheral nerve injury applications and compositions and method of use of synthetic hydrogel sealants
|
|
BR112014013175B1
(pt)
|
2011-12-02 |
2022-08-09 |
Pegasus Laboratories, Inc |
Processo para preparar comprimidos de composição de liberação prolongada
|
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
|
US9814867B2
(en)
|
2011-12-05 |
2017-11-14 |
Nano Precision Medical, Inc. |
Device having titania nanotube membrane for drug delivery
|
|
BR112014013664A2
(pt)
|
2011-12-05 |
2020-11-03 |
Factor Bioscience Inc. |
métodos e produtos para transfectar células
|
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
|
US9061063B2
(en)
|
2011-12-07 |
2015-06-23 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
|
AU2012347605B2
(en)
|
2011-12-07 |
2017-09-21 |
Alnylam Pharmaceuticals, Inc. |
Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents
|
|
US20140308304A1
(en)
|
2011-12-07 |
2014-10-16 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
|
WO2013086502A1
(en)
|
2011-12-09 |
2013-06-13 |
President And Fellows Of Harvard College |
Organ chips and uses thereof
|
|
EP2787977A4
(en)
|
2011-12-09 |
2015-05-06 |
Univ California |
LIPOSOMAL ACTIVE INVERTING
|
|
US9725687B2
(en)
|
2011-12-09 |
2017-08-08 |
President And Fellows Of Harvard College |
Integrated human organ-on-chip microphysiological systems
|
|
AU2012352455B2
(en)
|
2011-12-12 |
2016-01-21 |
The Trustees Of The University Of Pennsylvania |
Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections
|
|
JP6182458B2
(ja)
|
2011-12-12 |
2017-08-16 |
協和発酵キリン株式会社 |
カチオン性脂質の組み合わせを含有する脂質ナノ粒子
|
|
WO2013089151A1
(ja)
|
2011-12-12 |
2013-06-20 |
協和発酵キリン株式会社 |
カチオン性脂質を含有するドラッグデリバリーシステムのための脂質ナノ粒子
|
|
HUE052136T2
(hu)
|
2011-12-13 |
2021-04-28 |
Engeneic Molecular Delivery Pty Ltd |
Bakteriális eredetû intakt minisejtek terápiás szerek agydaganatokba történõ bejuttatására
|
|
EP2604253A1
(en)
|
2011-12-13 |
2013-06-19 |
Otto Glatter |
Water-in-oil emulsions and methods for their preparation
|
|
US20150000936A1
(en)
|
2011-12-13 |
2015-01-01 |
Schlumberger Technology Corporation |
Energization of an element with a thermally expandable material
|
|
US20140378538A1
(en)
|
2011-12-14 |
2014-12-25 |
Moderma Therapeutics, Inc. |
Methods of responding to a biothreat
|
|
US20140343129A1
(en)
|
2011-12-14 |
2014-11-20 |
Moderna Therapeutics, Inc. |
Modified nucleic acids, and acute care uses thereof
|
|
EP2790674B1
(en)
|
2011-12-15 |
2017-11-01 |
BioNTech AG |
Particles comprising single stranded rna and double stranded rna for immunomodulation
|
|
WO2013090897A1
(en)
|
2011-12-15 |
2013-06-20 |
The Trustees Of The University Of Pennsylvania |
Using adaptive immunity to detect drug resistance
|
|
EP2791169B1
(en)
|
2011-12-16 |
2017-07-19 |
Synthon Biopharmaceuticals B.V. |
Compounds and methods for treating inflammatory diseases
|
|
CA2859583C
(en)
|
2011-12-16 |
2020-02-18 |
Allergan, Inc. |
Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer
|
|
JP2015500712A
(ja)
|
2011-12-16 |
2015-01-08 |
ノバルティス アーゲー |
吸入プロファイルに依存しない薬剤送達のためのエアロゾル投与装置
|
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
|
CA2859205A1
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Alpha-aminoamidine polymers and uses thereof
|
|
EP4144378A1
(en)
|
2011-12-16 |
2023-03-08 |
ModernaTX, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
WO2013091001A1
(en)
|
2011-12-19 |
2013-06-27 |
The University Of Sydney |
A peptide-hydrogel composite
|
|
US9241829B2
(en)
|
2011-12-20 |
2016-01-26 |
Abbott Medical Optics Inc. |
Implantable intraocular drug delivery apparatus, system and method
|
|
CA2859691A1
(en)
|
2011-12-21 |
2013-06-27 |
Moderna Therapeutics, Inc. |
Methods of increasing the viability or longevity of an organ or organ explant
|
|
EP2793941A1
(en)
|
2011-12-23 |
2014-10-29 |
F.Hoffmann-La Roche Ag |
Articles of manufacture and methods for co-administration of antibodies
|
|
US10814115B2
(en)
|
2011-12-27 |
2020-10-27 |
Massachusetts Institute Of Technology |
Microneedle devices and uses thereof
|
|
US10596246B2
(en)
|
2011-12-29 |
2020-03-24 |
Glaxosmithkline Biological Sa |
Adjuvanted combinations of meningococcal factor H binding proteins
|
|
US20140371302A1
(en)
|
2011-12-29 |
2014-12-18 |
Modema Therapeutics, Inc. |
Modified mrnas encoding cell-penetrating polypeptides
|
|
LT3144389T
(lt)
|
2011-12-30 |
2018-08-10 |
Cellscript, Llc |
In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį
|
|
WO2013103659A1
(en)
*
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
|
WO2013103842A1
(en)
|
2012-01-06 |
2013-07-11 |
Michigan Life Therapeutics, Llc |
Methods of reducing risk of cardiovascular disease
|
|
US20150030576A1
(en)
|
2012-01-10 |
2015-01-29 |
Moderna Therapeutics, Inc. |
Methods and compositions for targeting agents into and across the blood-brain barrier
|
|
US9879254B2
(en)
|
2012-01-18 |
2018-01-30 |
The General Hosptial Corporation |
Targeting RNAs to microvesicles
|
|
SG11201404014PA
(en)
|
2012-01-26 |
2014-08-28 |
Life Technologies Corp |
Methods for increasing the infectivity of viruses
|
|
EP2807252B1
(en)
|
2012-01-26 |
2017-05-10 |
Life Technologies Corporation |
Methods for increasing the infectivity of viruses
|
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
JP6170074B2
(ja)
|
2012-02-09 |
2017-07-26 |
ライフ テクノロジーズ コーポレーション |
親水性ポリマー粒子およびその製造方法
|
|
WO2013120499A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
|
|
WO2013120500A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigen
|
|
WO2013120498A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded allergenic antigen or an autoimmune self-antigen
|
|
WO2013120497A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
|
|
EP3597209A1
(en)
|
2012-02-22 |
2020-01-22 |
Northwestern University |
Nanostructures for treating cancers and other conditions
|
|
US20140037573A1
(en)
|
2012-02-22 |
2014-02-06 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
|
US20130243867A1
(en)
|
2012-02-23 |
2013-09-19 |
University Of South Florida (A Florida Non-Profit Corporation) |
Micelle compositions and methods for their use
|
|
EP2819651A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget AS |
Use of an antibody and a particulate immunomodulator in therapy
|
|
EP2819652A1
(en)
|
2012-02-27 |
2015-01-07 |
Epitarget As |
Use of a particulate immunomodulator in cancer therapy
|
|
US20130224268A1
(en)
|
2012-02-27 |
2013-08-29 |
Newgen Biopharma Corp. |
Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same
|
|
US20150037334A1
(en)
|
2012-03-01 |
2015-02-05 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
|
US20130236504A1
(en)
|
2012-03-06 |
2013-09-12 |
Medical University Of South Carolina |
Delivery System for Enhancing Drug Efficacy
|
|
WO2013136234A1
(en)
|
2012-03-13 |
2013-09-19 |
University Of Kwazulu-Natal |
Transdermal delivery devices
|
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
|
US10159743B2
(en)
|
2012-03-16 |
2018-12-25 |
The Johns Hopkins University |
Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
|
|
HK1206270A1
(en)
|
2012-03-16 |
2016-01-08 |
The Johns Hopkins University |
Controlled release formulations for the delivery of hif-1 inhibitors
|
|
SG11201405552VA
(en)
|
2012-03-16 |
2014-10-30 |
Merck Patent Gmbh |
Targeting aminoacid lipids
|
|
WO2013142349A1
(en)
|
2012-03-23 |
2013-09-26 |
University Of Chicago |
Compositions and methods related to staphylococcal sbi
|
|
US9610346B2
(en)
|
2012-03-23 |
2017-04-04 |
International Aids Vaccine Initiative |
Recombinant viral vectors
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
EP2830991A1
(en)
|
2012-03-26 |
2015-02-04 |
President and Fellows of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
|
RU2660565C2
(ru)
|
2012-03-27 |
2018-07-06 |
Кьюрвак Аг |
Молекулы искусственной нуклеиновой кислоты, содержащие 5'utr гена top
|
|
DK2830594T3
(en)
|
2012-03-27 |
2018-08-13 |
Sirna Therapeutics Inc |
DIETHER-BASED BIOLOGICALLY DEGRADABLE CATIONIC LIPIDS FOR siRNA RELEASE
|
|
MX357803B
(es)
|
2012-03-27 |
2018-07-24 |
Curevac Ag |
Moléculas de ácido nucleico artificiales.
|
|
RU2658490C2
(ru)
|
2012-03-27 |
2018-06-21 |
Кьюрвак Аг |
Искусственные молекулы нуклеиновых кислот для улучшенной экспрессии белков или пептидов
|
|
CA2868030C
(en)
|
2012-03-29 |
2021-05-25 |
Shire Human Genetic Therapies, Inc. |
Lipid-derived neutral nanoparticles
|
|
AU2013243949A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
|
AU2013243954A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US20140275229A1
(en)
|
2012-04-02 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Modified polynucleotides encoding udp glucuronosyltransferase 1 family, polypeptide a1
|
|
US20150050354A1
(en)
|
2012-04-02 |
2015-02-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the treatment of otic diseases and conditions
|
|
US20150064115A1
(en)
|
2012-04-05 |
2015-03-05 |
University Of Florida Research Foundation, Inc. |
Neurophilic nanoparticles
|
|
WO2013151771A1
(en)
|
2012-04-05 |
2013-10-10 |
Massachusetts Institute Of Technology |
Immunostimulatory compositions and methods of use thereof
|
|
WO2013152351A2
(en)
|
2012-04-06 |
2013-10-10 |
The Trustees Of Columbia University In The City Of New York |
Fusion polypeptides and methods of use thereof
|
|
WO2013153550A2
(en)
|
2012-04-08 |
2013-10-17 |
Theracoat Ltd |
Reverse thermal hydrogel preparations for use in the treatment of disorders of the urothelium
|
|
EP3000833B1
(en)
|
2012-04-11 |
2019-09-04 |
Intezyne Technologies Inc. |
Micelles comprising a triblock copolymer and a therapeutic agent
|
|
US9603800B2
(en)
|
2012-04-12 |
2017-03-28 |
Yale University |
Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
|
|
WO2013155513A1
(en)
|
2012-04-13 |
2013-10-17 |
President And Fellows Of Harvard College |
Devices and methods for in vitro aerosol delivery
|
|
WO2013154766A1
(en)
|
2012-04-13 |
2013-10-17 |
New York University |
Microrna control of ldl receptor pathway
|
|
CA2842041A1
(en)
|
2012-04-18 |
2013-10-24 |
Arrowhead Research Corporation |
Poly(acrylate) polymers for in vivo nucleic acid delivery
|
|
EP2838877B1
(en)
|
2012-04-19 |
2018-09-12 |
Sirna Therapeutics, Inc. |
Novel diester and triester based low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
|
EP2841056A4
(en)
|
2012-04-23 |
2015-09-16 |
Massachusetts Inst Technology |
STABLE LAYER COATED PARTICLES
|
|
BR112014026639A8
(pt)
|
2012-04-25 |
2018-01-16 |
Regulus Therapeutics Inc |
compostos , métodos de inibição da atividade de mir-21 , método para diminuir a expressão de colágeno , método para tratar , prevenir ou atrasar o início de uma doença , método de tratamento de um distúrbio fibroproliferativo e usos de um composto.
|
|
JP6360039B2
(ja)
|
2012-05-03 |
2018-07-18 |
カラ ファーマシューティカルズ インコーポレイテッド |
複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法
|
|
WO2013166498A1
(en)
|
2012-05-04 |
2013-11-07 |
The Johns Hopkins University |
Lipid-based drug carriers for rapid penetration through mucus linings
|
|
US20150087671A1
(en)
|
2012-05-16 |
2015-03-26 |
Micell Technologies, Inc. |
Low burst sustained release lipophilic and biologic agent compositions
|
|
US9399672B2
(en)
|
2012-05-17 |
2016-07-26 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Hepatitis C virus neutralizing antibody
|
|
WO2013173693A1
(en)
|
2012-05-18 |
2013-11-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Nanoparticles with enhanced entry into cancer cells
|
|
US10307490B2
(en)
|
2012-05-23 |
2019-06-04 |
The Ohio State University |
Lipid nanoparticle compositions for antisense oligonucleotides delivery
|
|
US20150306249A1
(en)
|
2012-05-25 |
2015-10-29 |
Curevac Gmbh |
Reversible immobilization and/or controlled release of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
|
|
JP6335886B2
(ja)
|
2012-06-06 |
2018-05-30 |
ロマ ヴィスタ メディカル、インコーポレイテッド |
膨張可能な医療デバイス
|
|
US10245229B2
(en)
|
2012-06-08 |
2019-04-02 |
Translate Bio, Inc. |
Pulmonary delivery of mRNA to non-lung target cells
|
|
DK2858677T3
(da)
|
2012-06-08 |
2020-08-31 |
Ethris Gmbh |
Pulmonær levering af messenger rna
|
|
BR112014030714B1
(pt)
|
2012-06-08 |
2020-12-22 |
Nitto Denko Corporation |
composto de lipídeo ionizável, composição, veículo de fármaco e formulação farmacêutica
|
|
US20150218252A1
(en)
|
2012-06-20 |
2015-08-06 |
President And Fellows Of Harvard College |
Self-assembling peptides, peptide nanostructures and uses thereof
|
|
CN104507458B
(zh)
|
2012-06-20 |
2018-05-22 |
滑铁卢大学 |
粘膜粘合剂纳米颗粒递送系统
|
|
WO2014004436A2
(en)
|
2012-06-27 |
2014-01-03 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human il-23 antibodies
|
|
US9150841B2
(en)
|
2012-06-29 |
2015-10-06 |
Shire Human Genetic Therapies, Inc. |
Cells for producing recombinant iduronate-2-sulfatase
|
|
US9956291B2
(en)
|
2012-07-10 |
2018-05-01 |
Shaker A. Mousa |
Nanoformulation and methods of use of thyroid receptor beta1 agonists for liver targeting
|
|
WO2014014890A1
(en)
|
2012-07-16 |
2014-01-23 |
Nanoderm Sciences, Inc. |
Targeted therapeutic nanoparticles
|
|
EP2687252A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
|
EP2687251A1
(en)
|
2012-07-17 |
2014-01-22 |
Sanofi-Aventis Deutschland GmbH |
Drug delivery device
|
|
CN112587658A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
WO2014015334A1
(en)
|
2012-07-20 |
2014-01-23 |
Brown University |
System and methods for nanostructure protected delivery of treatment agent and selective release thereof
|
|
WO2014018675A1
(en)
|
2012-07-24 |
2014-01-30 |
President And Fellows Of Harvard College |
Self-assembly of nucleic acid nanostructures
|
|
GB201213624D0
(en)
|
2012-07-27 |
2012-09-12 |
Univ Ulster The |
Method and system for production of conjugated nanoparticles
|
|
WO2014015422A1
(en)
|
2012-07-27 |
2014-01-30 |
Ontario Institute For Cancer Research |
Cellulose-based nanoparticles for drug delivery
|
|
WO2014024193A1
(en)
|
2012-08-07 |
2014-02-13 |
Prodel Pharma Ltd. |
Compositions and methods for rapid transmucosal delivery of pharmaceutical ingredients
|
|
US9931418B2
(en)
|
2012-08-07 |
2018-04-03 |
Northeastern University |
Compositions for the delivery of RNA and drugs into cells
|
|
CN104582747B
(zh)
|
2012-08-08 |
2016-12-21 |
南洋理工大学 |
用于制造具有活细胞的水凝胶微粒的方法和用于制造组织工程支架的组合物
|
|
EP2882474A4
(en)
|
2012-08-08 |
2016-05-11 |
Presage Biosciences Inc |
EXTRUSION METHODS AND DEVICES FOR ACTIVE INGREDIENT RELIEF
|
|
AU2013299641A1
(en)
|
2012-08-10 |
2015-03-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids
|
|
EP2882706A1
(en)
|
2012-08-13 |
2015-06-17 |
Massachusetts Institute of Technology |
Amine-containing lipidoids and uses thereof
|
|
WO2014027006A1
(en)
|
2012-08-13 |
2014-02-20 |
Edko Pazarlama Tanitim Ticaret Limited Sirketi |
Bioadhesive formulations for use in drug delivery
|
|
US9512456B2
(en)
|
2012-08-14 |
2016-12-06 |
Modernatx, Inc. |
Enzymes and polymerases for the synthesis of RNA
|
|
WO2014026284A1
(en)
|
2012-08-14 |
2014-02-20 |
Froese Aaron |
Internal structured self assembling liposomes
|
|
US9827321B2
(en)
|
2012-08-14 |
2017-11-28 |
The Trustees Of The University Of Pennsylvania |
Stabilizing shear-thinning hydrogels
|
|
WO2014028763A1
(en)
|
2012-08-15 |
2014-02-20 |
The University Of Chicago |
Exosome-based therapeutics against neurodegenerative disorders
|
|
US10179134B2
(en)
|
2012-09-05 |
2019-01-15 |
Creighton University |
Polymeric nanoparticles in a thermosensitive gel for coital-independent vaginal prophylaxis of HIV
|
|
US8703197B2
(en)
|
2012-09-13 |
2014-04-22 |
International Business Machines Corporation |
Branched polyamines for delivery of biologically active materials
|
|
EP2895156B1
(en)
|
2012-09-17 |
2019-05-08 |
Pfizer Inc. |
Process for preparing therapeutic nanoparticles
|
|
WO2014047649A1
(en)
|
2012-09-24 |
2014-03-27 |
The Regents Of The University Of California |
Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
|
|
WO2014052634A1
(en)
|
2012-09-27 |
2014-04-03 |
The University Of North Carolina At Chapel Hill |
Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof
|
|
US20150307542A1
(en)
|
2012-10-03 |
2015-10-29 |
Moderna Therapeutics, Inc. |
Modified nucleic acid molecules and uses thereof
|
|
US20140100178A1
(en)
|
2012-10-04 |
2014-04-10 |
Aslam Ansari |
Composition and methods for site-specific drug delivery to treat malaria and other liver diseases
|
|
WO2014053882A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
WO2014053881A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
EP2716655A1
(en)
|
2012-10-04 |
2014-04-09 |
Institut Pasteur |
Neutralizing antibodies directed against Hepatitis C virus ectodomain glycoprotein E2
|
|
WO2014053879A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
WO2014053880A1
(en)
|
2012-10-04 |
2014-04-10 |
Centre National De La Recherche Scientifique |
Cell penetrating peptides for intracellular delivery of molecules
|
|
WO2014054026A1
(en)
|
2012-10-04 |
2014-04-10 |
University Of The Witwatersrand, Johannesburg |
Liposomal drug delivery system
|
|
WO2014064534A2
(en)
|
2012-10-05 |
2014-05-01 |
Chrontech Pharma Ab |
Injection needle, device, immunogenic compositions and method of use
|
|
EP2716689A1
(en)
|
2012-10-05 |
2014-04-09 |
National University of Ireland, Galway |
Polymer comprising a plurality of branches having at least one disulfide group and/or at least one vinyl group
|
|
US9931410B2
(en)
|
2012-10-09 |
2018-04-03 |
The Brigham And Women's Hospital, Inc. |
Nanoparticles for targeted delivery of multiple therapeutic agents and methods of use
|
|
US20140106260A1
(en)
|
2012-10-11 |
2014-04-17 |
The Trustees Of The University Of Pennsylvania |
Core-shell nanoparticulate compositions and methods
|
|
EP2908818A4
(en)
|
2012-10-16 |
2016-07-13 |
Endocyte Inc |
CONJUGATES OF DRUG DELIVERY CONTAINING ARTIFICIAL AMINO ACIDS AND METHODS OF USE
|
|
EA201992107A1
(ru)
|
2012-10-18 |
2020-04-30 |
Рокфеллер Юниверсити (Дзе) |
Нейтрализующие анти-вич-антитела широкого спектра действия
|
|
CN104918639B
(zh)
|
2012-10-22 |
2018-01-26 |
萨拜格Rfa公司 |
用于将治疗剂递送到活细胞和细胞核中的系统
|
|
US10172956B2
(en)
|
2012-10-26 |
2019-01-08 |
Vanderbilt University |
Polymeric nanoparticles
|
|
JP2016503394A
(ja)
|
2012-10-26 |
2016-02-04 |
エヌライフ、セラピューティックス、ソシエダッド、リミターダＮｌｉｆｅ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｓ．Ｌ． |
細胞型へのオリゴヌクレオチド分子の選択的送達のための組成物および方法
|
|
WO2014066898A1
(en)
|
2012-10-26 |
2014-05-01 |
The Johns Hopkins University |
A layer-by-layer approach to co-deliver dna and sirna via aunps: a potential platform for modifying release kinetics
|
|
WO2014067551A1
(en)
|
2012-10-29 |
2014-05-08 |
Technische Universität Dortmund |
T7 rna polymerase variants and methods of using the same
|
|
BR122019025681B1
(pt)
|
2012-11-01 |
2023-04-18 |
Factor Bioscience Inc |
Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula
|
|
WO2014071072A2
(en)
|
2012-11-02 |
2014-05-08 |
Pungente Michael D |
Novel cationic carotenoid-based lipids for cellular nucleic acid uptake
|
|
US10017767B2
(en)
|
2012-11-05 |
2018-07-10 |
Fondazione Centro San Raffaele |
Targets in multiple myeloma and other disorders
|
|
US9975916B2
(en)
|
2012-11-06 |
2018-05-22 |
President And Fellows Of Harvard College |
Compositions and methods relating to complex nucleic acid nanostructures
|
|
ES2962574T3
(es)
|
2012-11-06 |
2024-03-19 |
Rochal Tech Llc |
Administración de agentes biológicamente activos utilizando disolventes volátiles hidrófobos
|
|
EP2916873B1
(en)
|
2012-11-07 |
2017-07-26 |
Council of Scientific & Industrial Research |
Nanocomplex containing amphipathic peptide useful for efficient transfection of biomolecules
|
|
EP2916874B1
(en)
|
2012-11-07 |
2018-08-29 |
Council of Scientific and Industrial Research |
Nanocomplex containing cationic peptide for biomolecule delivery
|
|
TW201428101A
(zh)
|
2012-11-08 |
2014-07-16 |
Inviragen Inc |
登革熱病毒血清型４型之建構物的組成物、方法及用途
|
|
EP3721872B1
(en)
|
2012-11-08 |
2025-01-22 |
Clearside Biomedical Inc. |
Methods for the treatment of ocular disease in human subjects
|
|
JP6487328B2
(ja)
|
2012-11-08 |
2019-03-20 |
アルブミディクス リミティド |
アルブミン変異体
|
|
CN104903349B
(zh)
|
2012-11-08 |
2018-10-19 |
十一生物治疗股份有限公司 |
Il-6拮抗剂及其应用
|
|
WO2014072468A1
(en)
|
2012-11-09 |
2014-05-15 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
|
US9200119B2
(en)
|
2012-11-09 |
2015-12-01 |
Momentive Performance Materials Inc. |
Silicon-containing zwitterionic linear copolymer composition
|
|
WO2014071963A1
(en)
|
2012-11-09 |
2014-05-15 |
Biontech Ag |
Method for cellular rna expression
|
|
TR201809547T4
(tr)
|
2012-11-09 |
2018-07-23 |
Biontech Rna Pharmaceuticals Gmbh |
Hücresel RNA ifadesine yönelik yöntem.
|
|
US9833502B2
(en)
|
2012-11-12 |
2017-12-05 |
Genvec, Inc. |
Malaria antigens and methods of use
|
|
GB201220354D0
(en)
|
2012-11-12 |
2012-12-26 |
Medpharm Ltd |
Dermal compositions
|
|
JP2016500058A
(ja)
|
2012-11-12 |
2016-01-07 |
レッドウッド バイオサイエンス， インコーポレイテッド |
化合物および抱合体を生成するための方法
|
|
WO2014078399A1
(en)
|
2012-11-13 |
2014-05-22 |
Baylor College Of Medicine |
Multi-arm biodegradable polymers for nucleic acid delivery
|
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
WO2014078636A1
(en)
|
2012-11-16 |
2014-05-22 |
President And Fellows Of Harvard College |
Nucleic acid hydrogel self-assembly
|
|
EP2732825B1
(en)
|
2012-11-19 |
2015-07-01 |
Invivogen |
Conjugates of a TLR7 and/or TLR8 agonist and a TLR2 agonist
|
|
WO2014076709A1
(en)
|
2012-11-19 |
2014-05-22 |
Technion Research And Development Foundation Ltd. |
Liposomes for in-vivo delivery
|
|
WO2014081849A1
(en)
|
2012-11-20 |
2014-05-30 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
|
US20140141037A1
(en)
|
2012-11-20 |
2014-05-22 |
Novartis Ag |
Rsv f prefusion trimers
|
|
WO2014081300A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Channel protein activatable liposomes
|
|
FI2922574T3
(fi)
|
2012-11-22 |
2023-08-11 |
Tagworks Pharmaceuticals B V |
Kemiallisesti pilkkoutuva ryhmä
|
|
WO2014081299A1
(en)
|
2012-11-22 |
2014-05-30 |
Tagworks Pharmaceuticals B.V. |
Activatable liposomes
|
|
DK2922554T3
(en)
*
|
2012-11-26 |
2022-05-23 |
Modernatx Inc |
Terminalt modificeret rna
|
|
US20150315541A1
(en)
|
2012-12-13 |
2015-11-05 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for altering cell phenotype
|
|
JP2016506416A
(ja)
|
2013-01-10 |
2016-03-03 |
ノバルティス アーゲー |
インフルエンザウイルス免疫原性組成物およびその使用
|
|
JP2016504050A
(ja)
|
2013-01-17 |
2016-02-12 |
モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
細胞表現型の改変のためのシグナルセンサーポリヌクレオチド
|
|
EP2964234A4
(en)
|
2013-03-09 |
2016-12-07 |
Moderna Therapeutics Inc |
Heterologous untranslated regions for mrna
|
|
WO2014158795A1
(en)
|
2013-03-12 |
2014-10-02 |
Moderna Therapeutics, Inc. |
Diagnosis and treatment of fibrosis
|
|
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(en)
|
2013-03-13 |
2016-01-20 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
|
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(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
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(en)
|
2013-03-15 |
2017-03-01 |
Moderna Therapeutics, Inc. |
Ion exchange purification of mrna
|
|
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(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Analysis of mrna heterogeneity and stability
|
|
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(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Removal of dna fragments in mrna production process
|
|
EP3578652B1
(en)
|
2013-03-15 |
2023-07-12 |
ModernaTX, Inc. |
Ribonucleic acid purification
|
|
US20160032273A1
(en)
|
2013-03-15 |
2016-02-04 |
Moderna Therapeutics, Inc. |
Characterization of mrna molecules
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
WO2014152027A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Manufacturing methods for production of rna transcripts
|
|
DK3019619T3
(da)
|
2013-07-11 |
2021-10-11 |
Modernatx Inc |
Sammensætninger, der omfatter syntetiske polynukleotider, som koder for crispr-beslægtede proteiner, og syntetiske sgrna'er, og anvendelsesfremgangsmåder
|
|
WO2015007871A2
(en)
|
2013-07-17 |
2015-01-22 |
Ospedale San Raffaele S.R.L. |
Micrornas and autoimmune-immune mediated inflammatory disease
|
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
AU2014315287A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
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(en)
|
2013-09-13 |
2015-03-19 |
Moderna Therapeutics, Inc. |
Polynucleotide compositions containing amino acids
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
BR112016007255A2
(pt)
|
2013-10-03 |
2017-09-12 |
Moderna Therapeutics Inc |
polinucleotídeos que codificam receptor de lipoproteína de baixa densidade
|
|
CA2927393A1
(en)
|
2013-10-18 |
2015-04-23 |
Moderna Therapeutics, Inc. |
Compositions and methods for tolerizing cellular systems
|
|
US20170202979A1
(en)
|
2014-07-17 |
2017-07-20 |
Modernatx, Inc. |
Terminal modifications of polynucleotides
|
|
EP3041948B1
(en)
*
|
2014-11-10 |
2019-01-09 |
Modernatx, Inc. |
Alternative nucleic acid molecules containing reduced uracil content and uses thereof
|
|
RU2749113C2
(ru)
|
2015-04-22 |
2021-06-04 |
Куревак Аг |
Содержащая рнк композиция для лечения опухолевых заболеваний
|
|
SI3394093T1
(sl)
|
2015-12-23 |
2022-05-31 |
Modernatx, Inc. |
Metode uporabe liganda OX40, ki kodira polinukleotid
|