|
US20060106020A1
(en)
*
|
2004-04-28 |
2006-05-18 |
Rodgers James D |
Tetracyclic inhibitors of Janus kinases
|
|
AR054416A1
(es)
|
2004-12-22 |
2007-06-27 |
Incyte Corp |
Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas.
|
|
EP1928874A1
(en)
*
|
2005-09-16 |
2008-06-11 |
AstraZeneca AB |
Heterobicyclic compounds as glucokinase activators
|
|
CA2621261C
(en)
|
2005-09-22 |
2014-05-20 |
Incyte Corporation |
Azepine inhibitors of janus kinases
|
|
US8604042B2
(en)
*
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
US8133900B2
(en)
*
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
|
JP5191391B2
(ja)
*
|
2005-11-01 |
2013-05-08 |
ターゲジェン インコーポレーティッド |
キナーゼのビ−アリールメタ−ピリミジン阻害剤
|
|
SG10202003901UA
(en)
|
2005-12-13 |
2020-05-28 |
Incyte Holdings Corp |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors
|
|
EA200870117A1
(ru)
*
|
2005-12-23 |
2008-12-30 |
Смитклайн Бичам Корпорейшн |
Азаиндоловые ингибиторы аурора-киназ
|
|
PL2003132T3
(pl)
*
|
2006-04-03 |
2014-10-31 |
Astellas Pharma Inc |
Pochodne oksadiazolu jako agoniści S1P1
|
|
SG170828A1
(en)
*
|
2006-04-05 |
2011-05-30 |
Vertex Pharmaceuticals Inc Us |
Deazapurines useful as inhibitors of janus kinases
|
|
AU2007322033B2
(en)
|
2006-11-20 |
2013-07-11 |
President And Fellows Of Harvard College |
Methods, compositions, and kits for treating pain and pruritis
|
|
CA2673038C
(en)
*
|
2006-12-22 |
2015-12-15 |
Incyte Corporation |
Substituted tricyclic heteroaryl compounds as janus kinase inhibitors
|
|
KR20150036210A
(ko)
*
|
2007-06-13 |
2015-04-07 |
인사이트 코포레이션 |
야누스 키나제 억제제(R)―3―(4―(7H―피롤로[2,3-d]피리미딘―4―일)―1H―피라졸―1―일)―3―사이클로펜틸프로판니트릴의 염
|
|
CL2008001709A1
(es)
*
|
2007-06-13 |
2008-11-03 |
Incyte Corp |
Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
|
|
CA2692379A1
(en)
*
|
2007-07-02 |
2009-01-08 |
Boehringer Ingelheim International Gmbh |
Antiproliferative compounds based on 5-membered heterocycles
|
|
WO2009032338A1
(en)
*
|
2007-09-09 |
2009-03-12 |
University Of Florida Research Foundation |
Apratoxin therapeutic agents: mechanism and methods of treatment
|
|
WO2009049028A1
(en)
*
|
2007-10-09 |
2009-04-16 |
Targegen Inc. |
Pyrrolopyrimidine compounds and their use as janus kinase modulators
|
|
EP2211620B1
(en)
*
|
2007-10-25 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
3-PYRAZIN SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AS JANUS KINASE INHIBITORS FOR THE TREATMENT OF CANCER DISEASES
|
|
UA104849C2
(uk)
*
|
2007-11-16 |
2014-03-25 |
Інсайт Корпорейшн |
4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus
|
|
PE20091485A1
(es)
*
|
2008-02-06 |
2009-10-26 |
Novartis Ag |
DERIVADOS DE PIRROLO-[2,3-d]-PIRIMIDINA COMO INHIBIDORES DE CINASAS
|
|
WO2009114552A1
(en)
*
|
2008-03-10 |
2009-09-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Heteroaryl compounds, compositions, and methods of use in cancer treatment
|
|
HUE029767T2
(en)
|
2008-03-11 |
2017-04-28 |
Incyte Holdings Corp |
JAK inhibitor azetidine and cyclobutane derivatives
|
|
EP2278969B1
(en)
*
|
2008-04-21 |
2013-02-13 |
Merck Sharp & Dohme Corp. |
Inhibitors of Janus kinases
|
|
EP2274288A2
(en)
*
|
2008-04-24 |
2011-01-19 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
|
CL2009001152A1
(es)
|
2008-05-13 |
2009-10-16 |
Array Biopharma Inc |
Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa.
|
|
EP2299816B1
(en)
*
|
2008-06-18 |
2013-11-13 |
Merck Sharp & Dohme Corp. |
Inhibitors of janus kinases
|
|
WO2009155565A1
(en)
*
|
2008-06-20 |
2009-12-23 |
Genentech, Inc. |
Triazolopyridine jak inhibitor compounds and methods
|
|
CN102131389A
(zh)
*
|
2008-06-20 |
2011-07-20 |
健泰科生物技术公司 |
三唑并吡啶jak抑制剂化合物和方法
|
|
CL2009001884A1
(es)
*
|
2008-10-02 |
2010-05-14 |
Incyte Holdings Corp |
Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
|
|
AT507187B1
(de)
|
2008-10-23 |
2010-03-15 |
Helmut Dr Buchberger |
Inhalator
|
|
TWI720517B
(zh)
*
|
2009-01-15 |
2021-03-01 |
美商英塞特公司 |
製造jak抑制劑之方法及相關中間化合物
|
|
WO2010085597A1
(en)
*
|
2009-01-23 |
2010-07-29 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
|
SI2432472T1
(sl)
*
|
2009-05-22 |
2019-11-29 |
Incyte Holdings Corp |
3-(4-(7H-pirolo(2,3-d)pirimidin-4-il)-1H-pirazol-1-il)oktan- ali heptan-nitril kot inhibitorji JAK
|
|
AR076794A1
(es)
*
|
2009-05-22 |
2011-07-06 |
Incyte Corp |
Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen
|
|
ES2540964T3
(es)
|
2009-06-08 |
2015-07-15 |
Takeda Pharmaceutical Company Limited |
Compuestos de dihidropirrolonaftiridinona como inhibidores de JAK
|
|
KR101763656B1
(ko)
|
2009-06-29 |
2017-08-01 |
인사이트 홀딩스 코포레이션 |
Pi3k 저해물질로서의 피리미디논
|
|
JP6205133B2
(ja)
|
2009-07-10 |
2017-09-27 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
|
|
TWI466885B
(zh)
|
2009-07-31 |
2015-01-01 |
Japan Tobacco Inc |
含氮螺環化合物及其醫藥用途
|
|
TW201113285A
(en)
|
2009-09-01 |
2011-04-16 |
Incyte Corp |
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
|
EP2485589A4
(en)
*
|
2009-09-04 |
2013-02-06 |
Biogen Idec Inc |
HETEROARYL-BTK INHIBITORS
|
|
JP5658756B2
(ja)
|
2009-09-10 |
2015-01-28 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Jakの阻害剤
|
|
EP2482815B1
(en)
|
2009-10-02 |
2018-05-02 |
Avexxin AS |
Antiinflammatory 2-oxothiazoles and 2-oxooxazoles
|
|
EA021478B1
(ru)
*
|
2009-10-09 |
2015-06-30 |
Инсайт Корпорейшн |
ГИДРОКСИЛЬНЫЕ, КЕТО И ГЛЮКУРОНИДНЫЕ ПРОИЗВОДНЫЕ 3-(4-(7Н-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)-1Н-ПИРАЗОЛ-1-ИЛ)-3-ЦИКЛОПЕНТИЛПРОПАННИТРИЛА
|
|
US8389728B2
(en)
*
|
2009-11-06 |
2013-03-05 |
The Arizona Board Of Regents |
Pollen tube stimulants from Arabidopsis pistils
|
|
JP5858434B2
(ja)
*
|
2010-02-18 |
2016-02-10 |
インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation |
Janusキナーゼ阻害薬としてのシクロブタンおよびメチルシクロブタン誘導体
|
|
WO2011109217A2
(en)
*
|
2010-03-02 |
2011-09-09 |
Immunodiagnostics, Inc. |
Methods of treating or preventing rna polymerase dependent viral disorders by administration of jak2 kinase inhibitors
|
|
EP3354652B1
(en)
|
2010-03-10 |
2020-05-06 |
Incyte Holdings Corporation |
Piperidin-4-yl azetidine derivatives as jak1 inhibitors
|
|
AU2015205858B2
(en)
*
|
2010-03-10 |
2017-04-13 |
Incyte Holdings Corporation |
Piperidin-4-yl azetidine derivatives as jak1 inhibitors
|
|
KR20130094710A
(ko)
*
|
2010-04-14 |
2013-08-26 |
어레이 바이오파마 인크. |
Jak 키나아제의 억제제로서 5,7-치환된-이미다조[1,2-c]피리미딘
|
|
AR081626A1
(es)
|
2010-04-23 |
2012-10-10 |
Cytokinetics Inc |
Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
|
|
US9133123B2
(en)
|
2010-04-23 |
2015-09-15 |
Cytokinetics, Inc. |
Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
|
|
AR081331A1
(es)
|
2010-04-23 |
2012-08-08 |
Cytokinetics Inc |
Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
|
|
PE20130216A1
(es)
|
2010-05-21 |
2013-02-27 |
Incyte Corp |
Formulacion topica para un inhibidor de jak
|
|
KR101541086B1
(ko)
*
|
2010-08-20 |
2015-08-03 |
허치슨 메디파르마 리미티드 |
피롤로피리미딘 화합물 및 그 용도
|
|
WO2012040527A2
(en)
*
|
2010-09-24 |
2012-03-29 |
The Regents Of The University Of Michigan |
Deubiquitinase inhibitors and methods for use of the same
|
|
US9056855B2
(en)
|
2010-10-28 |
2015-06-16 |
Viamet Pharmaceuticals, Inc. |
Metalloenzyme inhibitor compounds
|
|
AU2010363329A1
(en)
|
2010-11-07 |
2013-05-09 |
Targegen, Inc. |
Compositions and methods for treating myelofibrosis
|
|
US9034884B2
(en)
|
2010-11-19 |
2015-05-19 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
|
|
PE20140146A1
(es)
*
|
2010-11-19 |
2014-02-06 |
Incyte Corp |
Derivados de pirrolopiridina y pirrolopirimidina sustituidos con ciclobutilo como inhibidores de jak
|
|
EA036970B1
(ru)
*
|
2010-11-19 |
2021-01-21 |
Инсайт Холдингс Корпорейшн |
Применение {1-{1-[3-фтор-2-(трифтометил)изоникотиноил] пиперидин-4-ил}-3-[4-(7h-пирроло[2,3-d]пиримидин-4-ил)-1н-пиразол-1-ил]азетидин-3-ил}ацетонитрила для лечения заболеваний, связанных с активностью jak1
|
|
JP6097998B2
(ja)
*
|
2010-12-16 |
2017-03-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ロイコトリエン生成のビアリールアミドインヒビター
|
|
EP3660016A1
(en)
|
2010-12-20 |
2020-06-03 |
Incyte Holdings Corporation |
N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
|
|
CA2824970C
(en)
|
2011-02-11 |
2016-05-03 |
Batmark Limited |
Inhaler component
|
|
ES2547916T3
(es)
|
2011-02-18 |
2015-10-09 |
Novartis Pharma Ag |
Terapia de combinación de inhibidores de mTOR/JAK
|
|
AR085392A1
(es)
*
|
2011-02-24 |
2013-09-25 |
Cephalon Inc |
Compuestos de azufre aromaticos sustituidos y metodos para su uso en el tratamiento y prevencion del cancer
|
|
CN103547580B
(zh)
|
2011-03-22 |
2016-12-07 |
阿迪维纳斯疗法有限公司 |
取代的稠合三环化合物、其组合物及医药用途
|
|
US8759380B2
(en)
|
2011-04-22 |
2014-06-24 |
Cytokinetics, Inc. |
Certain heterocycles, compositions thereof, and methods for their use
|
|
CN103502249A
(zh)
*
|
2011-05-17 |
2014-01-08 |
普林斯匹亚生物制药公司 |
作为酪氨酸激酶抑制剂的氮杂吲哚衍生物
|
|
PH12013502523A1
(en)
|
2011-06-14 |
2019-10-11 |
Novartis Ag |
Combination of panobinostat and ruxolitinib in the treatment of cancer such as a myeloproliferative neoplasm
|
|
CN103797010B
(zh)
*
|
2011-06-20 |
2016-02-24 |
因塞特控股公司 |
作为jak抑制剂的氮杂环丁烷基苯基、吡啶基或吡嗪基甲酰胺衍生物
|
|
ES2548414T3
(es)
|
2011-07-08 |
2015-10-16 |
Novartis Ag |
Novedosos derivados de pirrolo pirimidina
|
|
EP2741747A1
(en)
|
2011-08-10 |
2014-06-18 |
Novartis Pharma AG |
JAK P13K/mTOR COMBINATION THERAPY
|
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
|
PT3513793T
(pt)
|
2011-09-02 |
2021-05-10 |
Incyte Holdings Corp |
Heterociclilaminas como inibidores de pi3k
|
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
|
CA2849168A1
(en)
|
2011-09-22 |
2013-03-28 |
Merck Sharp & Dohme Corp. |
Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors
|
|
CN103987713A
(zh)
*
|
2011-10-12 |
2014-08-13 |
阵列生物制药公司 |
5,7-取代的咪唑并[1,2-c]嘧啶
|
|
ES3018133T3
(en)
|
2011-11-30 |
2025-05-14 |
Univ Emory |
Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
|
|
US10821111B2
(en)
|
2011-11-30 |
2020-11-03 |
Emory University |
Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
|
|
EP2788000B1
(en)
*
|
2011-12-06 |
2018-05-30 |
Merck Sharp & Dohme Corp. |
Pyrrolopyrimidines as janus kinase inhibitors
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
WO2013173506A2
(en)
|
2012-05-16 |
2013-11-21 |
Rigel Pharmaceuticals, Inc. |
Method of treating muscular degradation
|
|
TW201406761A
(zh)
|
2012-05-18 |
2014-02-16 |
Incyte Corp |
做爲jak抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
|
|
HRP20250965T1
(hr)
|
2012-06-15 |
2025-10-10 |
Sun Pharmaceutical Industries, Inc. |
Deuterirani derivati ruksolitiniba
|
|
JP6280546B2
(ja)
|
2012-06-26 |
2018-02-14 |
デル マー ファーマシューティカルズ |
ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
|
|
US20150246043A1
(en)
*
|
2012-07-27 |
2015-09-03 |
Ratiopharm Gmbh |
Oral dosage forms for modified release comprising ruxolitinib
|
|
BR112015002152B1
(pt)
|
2012-08-02 |
2021-04-27 |
Nerviano Medical Sciences S.R.L. |
Compostos de pirróis substituídos ativos como inibidores de quinases, processo para a preparação de tais compostos, composição farmacêutica, método in vitro para a inibição da atividade de proteínas quinases da família jak e produto compreendendo os referidos compostos
|
|
US9593115B2
(en)
|
2012-09-21 |
2017-03-14 |
Advinus Therapeutics Ltd. |
Substituted fused tricyclic compounds, compositions, and medicinal applications thereof
|
|
KR20150060839A
(ko)
*
|
2012-10-26 |
2015-06-03 |
에프. 호프만-라 로슈 아게 |
브루톤 티로신 키나아제의 억제제
|
|
TWI646099B
(zh)
|
2012-11-01 |
2019-01-01 |
英塞特控股公司 |
作爲jak抑制劑之三環稠合噻吩衍生物
|
|
PH12020551186B1
(en)
|
2012-11-15 |
2024-03-20 |
Incyte Holdings Corp |
Sustained-release dosage forms of ruxolitinib
|
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
US10130632B2
(en)
|
2012-11-27 |
2018-11-20 |
Beth Israel Deaconess Medical Center, Inc. |
Methods for treating renal disease
|
|
WO2014089296A2
(en)
*
|
2012-12-06 |
2014-06-12 |
Institute For Hepatitis And Virus Research |
Functionalized benzamide derivatives as antiviral agents against hbv infection
|
|
US9260426B2
(en)
*
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
|
EP2951164B1
(en)
|
2013-01-29 |
2019-06-05 |
Avexxin AS |
Antiinflammatory and antitumor 2-oxothiazoles compounds
|
|
WO2014124280A1
(en)
|
2013-02-08 |
2014-08-14 |
Institute For Myeloma & Bone Cancer Research |
Improved diagnostic, prognostic, and monitoring methods for multiple myeloma, chronic lymphocytic leukemia, and b-cell non-hodgkin lymphoma
|
|
US20150380681A1
(en)
*
|
2013-02-12 |
2015-12-31 |
Konica Minolta, Inc. |
Organic electroluminescent element and lighting device
|
|
RS62867B1
(sr)
|
2013-03-06 |
2022-02-28 |
Incyte Holdings Corp |
Postupci i intermedijeri za dobijanje inhibitora jak
|
|
US20140343034A1
(en)
|
2013-04-25 |
2014-11-20 |
Japan Tobacco Inc. |
Skin barrier function improving agent
|
|
HUE033587T2
(hu)
|
2013-05-17 |
2017-12-28 |
Incyte Corp |
Bipirazol-származékok mint JAK inhibitorok
|
|
SMT202000315T1
(it)
|
2013-08-07 |
2020-07-08 |
Incyte Corp |
Forme di dosaggio a rilascio prolungato per un inibitore di jak1
|
|
CA2921568A1
(en)
*
|
2013-08-20 |
2015-02-25 |
Incyte Corporation |
Survival benefit in patients with solid tumors with elevated c-reactive protein levels
|
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
US9611263B2
(en)
|
2013-10-08 |
2017-04-04 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
|
CN105636962B
(zh)
*
|
2013-10-15 |
2017-10-13 |
靳博涵 |
新型化合物、用途及其制备方法
|
|
MX2016006894A
(es)
|
2013-11-27 |
2016-08-17 |
Novartis Ag |
Terapia de combinacion que comprende un inhibidor de jak, cdk y pim.
|
|
SI3077395T1
(en)
|
2013-12-05 |
2018-03-30 |
Pfizer Inc. |
Pyrrolo(2,3-d)pyrimidinyl, pyrrolo(2,3-b)pyrazinyl and pyrrolo(2,3-d)pyridinyl acrylamides
|
|
JP6367545B2
(ja)
*
|
2013-12-17 |
2018-08-01 |
コンサート ファーマシューティカルズ インコーポレイテッド |
ルキソリチニブの重水素化誘導体
|
|
CN110229159B
(zh)
*
|
2013-12-18 |
2021-08-24 |
康塞特医药品有限公司 |
卢索替尼的氘代衍生物
|
|
KR102261733B1
(ko)
*
|
2013-12-18 |
2021-06-04 |
콘서트 파마슈티컬즈, 인크. |
룩소리티닙의 중수소화된 유도체
|
|
PE20170255A1
(es)
|
2014-01-24 |
2017-03-22 |
Dana Farber Cancer Inst Inc |
Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
|
|
HUE045065T2
(hu)
|
2014-01-31 |
2019-12-30 |
Novartis Ag |
TIM-3 antitest molekulák és felhasználásaik
|
|
WO2015131080A1
(en)
|
2014-02-28 |
2015-09-03 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
|
KR20160136323A
(ko)
|
2014-02-28 |
2016-11-29 |
인사이트 코포레이션 |
골수형성이상증후군 치료용 jak1 억제제
|
|
KR102442436B1
(ko)
|
2014-03-14 |
2022-09-15 |
노파르티스 아게 |
Lag-3에 대한 항체 분자 및 그의 용도
|
|
SI3129021T1
(sl)
|
2014-04-08 |
2021-07-30 |
Incyte Corporation |
Zdravljenje malignosti B-celic s kombinacijo zaviralcev JAK in PI3K
|
|
MA39987A
(fr)
|
2014-04-30 |
2017-03-08 |
Incyte Corp |
Procédés de préparation d'un inhibiteur de jak1 et nouvelles formes associées
|
|
RU2564891C1
(ru)
*
|
2014-05-27 |
2015-10-10 |
Александр Александрович Кролевец |
Способ получения нанокапсул цитокининов
|
|
WO2015184087A2
(en)
*
|
2014-05-28 |
2015-12-03 |
Institute For Myeloma & Bone Cancer Research |
Anti-cancer effects of jak2 inhibitors in combination with thalidomide derivatives and glucocorticoids
|
|
US9498467B2
(en)
|
2014-05-30 |
2016-11-22 |
Incyte Corporation |
Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
|
|
CN105218548A
(zh)
*
|
2014-06-09 |
2016-01-06 |
上海海和药物研究开发有限公司 |
一种新型杂环化合物及其制备方法和作为激酶抑制剂的用途
|
|
WO2015191677A1
(en)
|
2014-06-11 |
2015-12-17 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
|
|
NZ629796A
(en)
*
|
2014-07-14 |
2015-12-24 |
Signal Pharm Llc |
Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
|
|
WO2016010886A1
(en)
*
|
2014-07-14 |
2016-01-21 |
Signal Pharmaceuticals, Llc |
Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof
|
|
GB201413695D0
(en)
|
2014-08-01 |
2014-09-17 |
Avexxin As |
Compound
|
|
AR101504A1
(es)
|
2014-08-11 |
2016-12-21 |
Acerta Pharma Bv |
Combinaciones terapéuticas de un inhibidor de la btk, un inhibidor de la pi3k, un inhibidor de la jak-2, y/o un inhibidor de la cdk4/6
|
|
TW201618775A
(zh)
|
2014-08-11 |
2016-06-01 |
艾森塔製藥公司 |
Btk抑制劑、pi3k抑制劑、jak-2抑制劑、pd-1抑制劑及/或pd-l1抑制劑之治療組合物
|
|
PL3179991T3
(pl)
|
2014-08-11 |
2022-02-14 |
Acerta Pharma B.V. |
Kombinacje terapeutyczne inhibitora btk i inhibitora bcl-2
|
|
CN117088931A
(zh)
|
2014-08-12 |
2023-11-21 |
莫纳什大学 |
定向淋巴的前药
|
|
EP3183252B1
(en)
*
|
2014-08-21 |
2021-05-12 |
ratiopharm GmbH |
Oxalate salt of ruxolitinib
|
|
KR20170060042A
(ko)
|
2014-09-13 |
2017-05-31 |
노파르티스 아게 |
Alk 억제제의 조합 요법
|
|
CN105524067A
(zh)
*
|
2014-09-28 |
2016-04-27 |
江苏柯菲平医药股份有限公司 |
4-取代吡咯并[2,3-d]嘧啶化合物及其用途
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
EP4245376A3
(en)
|
2014-10-14 |
2023-12-13 |
Novartis AG |
Antibody molecules to pd-l1 and uses thereof
|
|
WO2016063294A2
(en)
*
|
2014-10-20 |
2016-04-28 |
Msn Laboratories Private Limited |
Process for the preparation of (r)-3-(4-(7h-pyrrolo[2,3-d], pyrimidin-4-yl)-1 h-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate and its polymorphs thereof
|
|
CN107148425B
(zh)
|
2014-10-29 |
2021-08-03 |
拜斯科阿迪有限公司 |
对mt1-mmp特异性的双环肽配体
|
|
GB2535427A
(en)
|
2014-11-07 |
2016-08-24 |
Nicoventures Holdings Ltd |
Solution
|
|
CZ2014773A3
(cs)
|
2014-11-10 |
2016-05-18 |
Zentiva, K.S. |
Soli (3R)-3-cyklopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propannitrilu
|
|
CN105777754B
(zh)
*
|
2014-12-16 |
2019-07-26 |
北京赛林泰医药技术有限公司 |
吡咯并嘧啶化合物
|
|
SG10201907576SA
(en)
|
2015-02-27 |
2019-09-27 |
Incyte Corp |
Salts of pi3k inhibitor and processes for their preparation
|
|
TWI788655B
(zh)
|
2015-02-27 |
2023-01-01 |
美商林伯士拉克許米公司 |
酪胺酸蛋白質激酶2(tyk2)抑制劑及其用途
|
|
EA035817B1
(ru)
|
2015-03-10 |
2020-08-14 |
Адуро Байотек, Инк. |
Композиции и способы для активации сигналинга, зависимого от "гена стимулятора интерферона"
|
|
KR101859170B1
(ko)
*
|
2015-04-17 |
2018-05-17 |
광주과학기술원 |
트리아졸 화합물 및 이의 용도
|
|
AU2016254385B2
(en)
*
|
2015-04-29 |
2018-05-10 |
Wuxi Fortune Pharmaceutical Co., Ltd |
JAK inhibitors
|
|
US9840503B2
(en)
|
2015-05-11 |
2017-12-12 |
Incyte Corporation |
Heterocyclic compounds and uses thereof
|
|
US9732097B2
(en)
|
2015-05-11 |
2017-08-15 |
Incyte Corporation |
Process for the synthesis of a phosphoinositide 3-kinase inhibitor
|
|
US9988401B2
(en)
|
2015-05-11 |
2018-06-05 |
Incyte Corporation |
Crystalline forms of a PI3K inhibitor
|
|
WO2017004134A1
(en)
|
2015-06-29 |
2017-01-05 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
CZ2015496A3
(cs)
|
2015-07-14 |
2017-01-25 |
Zentiva, K.S. |
Krystalické formy solí (3R)-3-cyklopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propannitrilu a jejich příprava
|
|
WO2017011720A1
(en)
*
|
2015-07-16 |
2017-01-19 |
Signal Pharmaceuticals, Llc |
Solod forms 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d] oxazol-6-yl)17h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
|
HRP20211058T8
(hr)
|
2015-07-29 |
2021-11-26 |
Novartis Ag |
Kombinirane terapije koje sadrže molekule antitijela protiv lag-3
|
|
KR20180069782A
(ko)
|
2015-08-03 |
2018-06-25 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
하전 이온 채널 블록커 및 이용 방법
|
|
US9708333B2
(en)
|
2015-08-12 |
2017-07-18 |
Incyte Corporation |
Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
|
|
WO2017035366A1
(en)
*
|
2015-08-26 |
2017-03-02 |
Incyte Corporation |
Pyrrolopyrimidine derivatives as tam inhibitors
|
|
TWI707852B
(zh)
|
2015-09-02 |
2020-10-21 |
美商林伯士拉克許米公司 |
Tyk2 抑制劑及其用途
|
|
US11738087B2
(en)
|
2015-09-08 |
2023-08-29 |
Monash University |
Lymph directing prodrugs
|
|
US10683308B2
(en)
|
2015-09-11 |
2020-06-16 |
Navitor Pharmaceuticals, Inc. |
Rapamycin analogs and uses thereof
|
|
GB2542838B
(en)
|
2015-10-01 |
2022-01-12 |
Nicoventures Trading Ltd |
Aerosol provision system
|
|
AU2016342027B2
(en)
|
2015-10-23 |
2021-05-13 |
Navitor Pharmaceuticals, Inc. |
Modulators of Sestrin-GATOR2 interaction and uses thereof
|
|
PE20181326A1
(es)
|
2015-11-03 |
2018-08-20 |
Janssen Biotech Inc |
Anticuerpos que se unen especificamente a pd-1 y sus usos
|
|
PT3371190T
(pt)
|
2015-11-06 |
2022-07-08 |
Incyte Corp |
Compostos heterocíclicos como inibidores de pi3k-gamma
|
|
EP3373937B1
(en)
|
2015-11-09 |
2021-12-22 |
R.P. Scherer Technologies, LLC |
Anti-cd22 antibody-maytansine conjugates and methods of use thereof
|
|
RU2601410C1
(ru)
*
|
2015-11-13 |
2016-11-10 |
ЗАО "Р-Фарм" |
{3-[(7H-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)АЗОЛИЛ]АЗЕТИДИН-3-ИЛ}АЦЕТОНИТРИЛЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ЯНУС КИНАЗ
|
|
EP3389664A4
(en)
|
2015-12-14 |
2020-01-08 |
Raze Therapeutics Inc. |
MTHFD2 CAFFEIN INHIBITORS AND USES THEREOF
|
|
CN108368115B
(zh)
*
|
2015-12-15 |
2020-01-03 |
正大天晴药业集团股份有限公司 |
吡咯并嘧啶化合物的盐
|
|
US20200261573A1
(en)
|
2015-12-17 |
2020-08-20 |
Novartis Ag |
Combination of c-met inhibitor with antibody molecule to pd-1 and uses thereof
|
|
ES2986067T3
(es)
|
2015-12-17 |
2024-11-08 |
Novartis Ag |
Moléculas de anticuerpos frente a PD-1 y usos de las mismas
|
|
US9630968B1
(en)
|
2015-12-23 |
2017-04-25 |
Arqule, Inc. |
Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
|
|
US10562904B2
(en)
|
2015-12-31 |
2020-02-18 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Synthesis process of ruxolitinib
|
|
ES2898329T3
(es)
|
2016-01-12 |
2022-03-07 |
Oncotracker Inc |
Métodos mejorados para supervisar el estado inmunitario de un sujeto
|
|
CZ201629A3
(cs)
|
2016-01-22 |
2017-08-02 |
Zentiva, K.S. |
Krystalické modifikace solí (3R)-3-cyklopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propannitrilu a způsoby jejich přípravy
|
|
CN106905322B
(zh)
*
|
2016-01-26 |
2019-10-15 |
杭州华东医药集团新药研究院有限公司 |
吡咯嘧啶五元氮杂环衍生物及其应用
|
|
CN105541891B
(zh)
*
|
2016-02-04 |
2017-11-28 |
东南大学 |
巴瑞替尼的中间体及其制备方法及由该中间体制备巴瑞替尼的方法
|
|
DK3426243T3
(da)
|
2016-03-09 |
2021-07-19 |
Raze Therapeutics Inc |
3-phosphoglyceratdehydrogenase-inhibitorer og anvendelser deraf
|
|
EP4234552A3
(en)
|
2016-03-09 |
2023-10-18 |
Raze Therapeutics, Inc. |
3-phosphoglycerate dehydrogenase inhibitors and uses thereof
|
|
GB201604318D0
(en)
|
2016-03-14 |
2016-04-27 |
Avexxin As |
Combination therapy
|
|
KR102483020B1
(ko)
|
2016-03-28 |
2023-01-04 |
인사이트 코포레이션 |
Tam 저해제로서의 피롤로트리아진 화합물
|
|
CA3019394A1
(en)
|
2016-04-08 |
2017-10-12 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
|
ES2988629T3
(es)
|
2016-05-04 |
2024-11-21 |
Sun Pharmaceutical Ind Inc |
Tratamiento de trastornos de pérdida de cabello con inhibidores de JAK deuterados
|
|
MX394560B
(es)
|
2016-06-01 |
2025-03-24 |
Bayer Pharma AG |
Uso de indazoles sustituidos para el tratamiento y la prevencion de enfermedades en animales.
|
|
CN107513067A
(zh)
*
|
2016-06-16 |
2017-12-26 |
北京赛林泰医药技术有限公司 |
含有取代环戊基的吡咯并嘧啶化合物
|
|
CN107513069A
(zh)
*
|
2016-06-16 |
2017-12-26 |
正大天晴药业集团股份有限公司 |
手性吡咯并嘧啶化合物的制备方法
|
|
CN107759600A
(zh)
*
|
2016-06-16 |
2018-03-06 |
正大天晴药业集团股份有限公司 |
作为jak抑制剂的吡咯并嘧啶化合物的结晶
|
|
ES2870920T3
(es)
|
2016-06-21 |
2021-10-28 |
X4 Pharmaceuticals Inc |
Inhibidores de CXCR4 y usos de los mismos
|
|
CN109640988A
(zh)
|
2016-06-21 |
2019-04-16 |
X4 制药有限公司 |
Cxcr4抑制剂及其用途
|
|
EP3472129A4
(en)
|
2016-06-21 |
2019-12-04 |
X4 Pharmaceuticals, Inc. |
CXCR4 INHIBITORS AND USES THEREOF
|
|
MX388591B
(es)
|
2016-06-30 |
2025-03-20 |
Daewoong Pharmaceutical Co Ltd |
Derivados de pirazolopirimidina como inhibidor de cinasa.
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
KR102598246B1
(ko)
*
|
2016-07-26 |
2023-11-02 |
톈진 롱보진 파마시우티컬 씨오., 엘티디. |
Jak 저해제로서 헤테로사이클릭 화합물, 및 이의 염 및 치료학적 용도
|
|
TW201811795A
(zh)
|
2016-08-24 |
2018-04-01 |
美商亞闊股份有限公司 |
胺基-吡咯并嘧啶酮化合物及其用途
|
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
|
IT201600092051A1
(it)
*
|
2016-09-13 |
2018-03-13 |
Alessandro Antonelli |
Composto medicale per il trattamento di tumori della tiroide
|
|
US10323036B2
(en)
|
2016-10-14 |
2019-06-18 |
Nimbus Lakshmi, Inc. |
TYK2 inhibitors and uses thereof
|
|
EP3528816A4
(en)
|
2016-10-21 |
2020-04-08 |
Nimbus Lakshmi, Inc. |
TYK2 INHIBITORS AND USES THEREOF
|
|
WO2018089499A1
(en)
|
2016-11-08 |
2018-05-17 |
Navitor Pharmaceuticals, Inc. |
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
|
|
CA3043768A1
(en)
|
2016-11-29 |
2018-06-07 |
PureTech Health LLC |
Exosomes for delivery of therapeutic agents
|
|
US11091451B2
(en)
|
2016-12-05 |
2021-08-17 |
Raze Therapeutics, Inc. |
SHMT inhibitors and uses thereof
|
|
RU2644155C1
(ru)
*
|
2016-12-12 |
2018-02-08 |
Закрытое акционерное общество "Р-Фарм" (ЗАО "Р-Фарм") |
2-(3-(4-(7H-пирроло[2,3-d]пиримидин-4-ил)-1H-пиразол-1-ил)-1-(этилсульфонил)азетидин-3-ил)ацетонитрила геминафтилдисульфонат в качестве ингибитора Янус киназ
|
|
WO2018115203A1
(en)
|
2016-12-23 |
2018-06-28 |
Bicyclerd Limited |
Peptide derivatives having novel linkage structures
|
|
US10624968B2
(en)
|
2017-01-06 |
2020-04-21 |
Bicyclerd Limited |
Compounds for treating cancer
|
|
EA039352B1
(ru)
*
|
2017-01-19 |
2022-01-17 |
Сучжоу Лонгбайотек Фармасьютикалз Ко., Лтд. |
Соединение в качестве селективного ингибитора jak и его соли и терапевтическое применение
|
|
TW202515876A
(zh)
|
2017-03-08 |
2025-04-16 |
日商武田藥品工業股份有限公司 |
Tyk2抑制劑及其用途
|
|
EP3375784A1
(en)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aza-dihydro-acridone derivatives
|
|
EP3375778A1
(en)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aryl-piperidine derivatives
|
|
WO2018191146A1
(en)
|
2017-04-10 |
2018-10-18 |
Navitor Pharmaceuticals, Inc. |
Heteroaryl rheb inhibitors and uses thereof
|
|
JOP20180036A1
(ar)
|
2017-04-18 |
2019-01-30 |
Vifor Int Ag |
أملاح لمثبطات فروبورتين جديدة
|
|
PL3615019T3
(pl)
|
2017-04-26 |
2026-01-19 |
Navitor Pharmaceuticals, Inc. |
Modulator interakcji sestryna-gator2 do zastosowania w leczeniu depresji opornej na leczenie
|
|
US10857196B2
(en)
|
2017-04-27 |
2020-12-08 |
Bicycletx Limited |
Bicyclic peptide ligands and uses thereof
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
PH12019502605A1
(en)
|
2017-05-23 |
2020-10-26 |
Theravance Biopharma R&D Ip Llc |
Glucuronide prodrugs of janus kinase inhibitors
|
|
US11635435B2
(en)
|
2017-06-13 |
2023-04-25 |
Oncotracker, Inc. |
Diagnostic, prognostic, and monitoring methods for solid tumor cancers
|
|
MY204117A
(en)
|
2017-06-22 |
2024-08-08 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
EP3645549A1
(en)
|
2017-06-26 |
2020-05-06 |
BicycleRD Limited |
Bicyclic peptide ligands with detectable moieties and uses thereof
|
|
CN107298680A
(zh)
*
|
2017-07-12 |
2017-10-27 |
海门华祥医药科技有限公司 |
一种4‑氯‑7‑氮杂吲哚的生产工艺
|
|
SI3658557T1
(sl)
|
2017-07-28 |
2024-10-30 |
Takeda Pharmaceutical Company Limited |
Zaviralci TYK2 in njihova uporaba
|
|
JP7670481B2
(ja)
|
2017-08-04 |
2025-04-30 |
バイスクルテクス・リミテッド |
Cd137に対して特異的な二環式ペプチドリガンド
|
|
WO2019034866A1
(en)
|
2017-08-14 |
2019-02-21 |
Bicyclerd Limited |
BICYCLIC PEPTIDE LIGANDS CONJUGATES AND USES THEREOF
|
|
WO2019034868A1
(en)
|
2017-08-14 |
2019-02-21 |
Bicyclerd Limited |
CONJUGATES PEPTIDE BICYCLIC-LIGAND PPR-A AND USES THEREOF
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
CA3077739A1
(en)
|
2017-08-29 |
2019-03-07 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
WO2019060742A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc |
AGENTS FOR DEGRADING PROTEINS AND USES THEREOF
|
|
US11358948B2
(en)
|
2017-09-22 |
2022-06-14 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
|
MA50655B1
(fr)
|
2017-09-27 |
2021-11-30 |
Incyte Corp |
Sels de dérivés de pyrrolotriazine utiles en tant qu'inhibiteurs de tam
|
|
CN109651424B
(zh)
*
|
2017-10-11 |
2021-01-22 |
新发药业有限公司 |
一种7-保护基-4-(1-氢-吡唑-4-基)吡咯[2,3-d]嘧啶的合成方法
|
|
WO2019090143A1
(en)
*
|
2017-11-03 |
2019-05-09 |
Aclaris Therapeutics, Inc. |
Pyrazolyl pyrrolo[2,3-b]pyrimidine-5-carboxylate analogs and methods of making the same
|
|
KR102821964B1
(ko)
|
2017-11-03 |
2025-06-19 |
어클라리스 쎄라퓨틱스, 인코포레이티드 |
치환된 피롤로피리미딘 jak 억제제 및 이의 제조 및 사용 방법
|
|
KR102034538B1
(ko)
|
2017-11-28 |
2019-10-21 |
주식회사한국파마 |
Jak 저해제 화합물, 및 이의 제조방법
|
|
WO2019113487A1
(en)
|
2017-12-08 |
2019-06-13 |
Incyte Corporation |
Low dose combination therapy for treatment of myeloproliferative neoplasms
|
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
EP3727362A4
(en)
|
2017-12-19 |
2021-10-06 |
PureTech LYT, Inc. |
MYCOPHENOLIC ACID LIPID PRODRUGS AND THEIR USES
|
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
|
TWI825046B
(zh)
|
2017-12-19 |
2023-12-11 |
英商拜西可泰克斯有限公司 |
Epha2特用之雙環胜肽配位基
|
|
GB201721265D0
(en)
|
2017-12-19 |
2018-01-31 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for EphA2
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
WO2019140380A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
JP7229257B2
(ja)
|
2018-01-29 |
2023-02-28 |
メルク パテント ゲーエムベーハー |
Gcn2阻害剤およびその使用
|
|
BR112020015396A2
(pt)
|
2018-01-29 |
2020-12-08 |
Merck Patent Gmbh |
Inididores de gcn2 e usos dos mesmos
|
|
SG11202007164UA
(en)
|
2018-01-30 |
2020-08-28 |
Incyte Corp |
Processes for preparing (1 -(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one)
|
|
KR102925957B1
(ko)
|
2018-02-16 |
2026-02-11 |
인사이트 코포레이션 |
사이토카인-관련 장애의 치료를 위한 jak1 경로 억제제
|
|
CN111902429A
(zh)
|
2018-02-23 |
2020-11-06 |
拜斯科技术开发有限公司 |
多聚体双环肽配体
|
|
JP7050165B2
(ja)
|
2018-02-26 |
2022-04-07 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hbv複製阻害剤としての置換ピロリジン化合物
|
|
EP3759086A1
(en)
|
2018-02-27 |
2021-01-06 |
Artax Biopharma Inc. |
Chromene derivatives as inhibitors of tcr-nck interaction
|
|
CA3092931A1
(en)
|
2018-03-08 |
2019-09-12 |
Novartis Ag |
Use of an anti-p-selectin antibody
|
|
CN110357887B
(zh)
*
|
2018-03-26 |
2022-09-16 |
武汉誉祥医药科技有限公司 |
取代的7H-吡咯并[2,3-d]嘧啶衍生物及其制备方法和用途
|
|
MA52655A
(fr)
|
2018-03-30 |
2021-02-17 |
Incyte Corp |
Biomarqueurs pour maladie cutanée inflammatoire
|
|
SMT202400306T1
(it)
|
2018-03-30 |
2024-09-16 |
Incyte Corp |
Trattamento dell'idrosadenite suppurativa utilizzando inibitori di jak.
|
|
CA3097025A1
(en)
|
2018-04-13 |
2019-10-17 |
Incyte Corporation |
Biomarkers for graft-versus-host disease
|
|
ES2969982T3
(es)
|
2018-04-24 |
2024-05-23 |
Vertex Pharma |
Compuestos de pteridinona y usos de los mismos
|
|
HRP20241163T1
(hr)
|
2018-04-24 |
2024-11-22 |
Merck Patent Gmbh |
Antiproliferacijski spojevi i njihova uporaba
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
SG11202011680YA
(en)
|
2018-06-01 |
2020-12-30 |
Incyte Corp |
Dosing regimen for the treatment of pi3k related disorders
|
|
EP3805219A4
(en)
*
|
2018-06-06 |
2022-03-23 |
Gengle Therapeutics, Inc. |
PYRAZOLOPYRIMIDI DERIVATIVE, ITS USE AND PHARMACEUTICAL COMPOSITION
|
|
WO2019241789A1
(en)
|
2018-06-15 |
2019-12-19 |
Navitor Pharmaceuticals, Inc. |
Rapamycin analogs and uses thereof
|
|
IL279489B2
(en)
|
2018-06-22 |
2025-10-01 |
Bicycletx Ltd |
Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
|
|
GB201810316D0
(en)
|
2018-06-22 |
2018-08-08 |
Bicyclerd Ltd |
Peptide ligands for binding to EphA2
|
|
AR117600A1
(es)
|
2018-06-29 |
2021-08-18 |
Incyte Corp |
Formulaciones de un inhibidor de axl / mer
|
|
JP6830460B2
(ja)
*
|
2018-07-05 |
2021-02-17 |
コンサート ファーマシューティカルズ インコーポレイテッド |
ルキソリチニブの重水素化誘導体
|
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
CN117285467A
(zh)
|
2018-07-31 |
2023-12-26 |
罗索肿瘤学公司 |
喷雾干燥的分散体和制剂
|
|
CN119080779A
(zh)
|
2018-08-10 |
2024-12-06 |
阿克拉瑞斯治疗股份有限公司 |
吡咯并嘧啶itk抑制剂
|
|
WO2020039401A1
(en)
|
2018-08-24 |
2020-02-27 |
Novartis Ag |
Treatment comprising il-1βeta binding antibodies and combinations thereof
|
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
|
WO2020051424A1
(en)
|
2018-09-07 |
2020-03-12 |
Pic Therapeutics |
Eif4e inhibitors and uses thereof
|
|
CN113271940A
(zh)
|
2018-10-15 |
2021-08-17 |
林伯士拉克许米公司 |
Tyk2抑制剂和其用途
|
|
WO2020084305A1
(en)
|
2018-10-23 |
2020-04-30 |
Bicycletx Limited |
Bicyclic peptide ligands and uses thereof
|
|
EP3870158A4
(en)
|
2018-10-24 |
2022-08-10 |
Navitor Pharmaceuticals, Inc. |
Polymorphic compounds and uses thereof
|
|
CA3117969A1
(en)
|
2018-10-31 |
2020-05-07 |
Incyte Corporation |
Combination therapy for treatment of hematological diseases
|
|
CA3120866A1
(en)
|
2018-11-30 |
2020-06-04 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
|
CA3119773A1
(en)
|
2018-11-30 |
2020-06-04 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
CN109394768B
(zh)
*
|
2018-12-10 |
2019-08-23 |
牡丹江医学院 |
一种治疗湿疹的药物及其制备方法
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
CN111320633B
(zh)
*
|
2018-12-14 |
2022-09-27 |
中国医药研究开发中心有限公司 |
吡咯/咪唑并六元杂芳环类化合物及其制备方法和医药用途
|
|
US12351571B2
(en)
|
2018-12-19 |
2025-07-08 |
Array Biopharma Inc. |
Substituted quinoxaline compounds as inhibitors of FGFR tyrosine kinases
|
|
EP3898626A1
(en)
|
2018-12-19 |
2021-10-27 |
Array Biopharma, Inc. |
Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
US20220040324A1
(en)
|
2018-12-21 |
2022-02-10 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and kinase inhibitor
|
|
WO2020128527A1
(en)
|
2018-12-21 |
2020-06-25 |
Bicyclerd Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
US12492224B2
(en)
|
2018-12-21 |
2025-12-09 |
Bicycletx Limited |
Bicyclic peptide ligands specific for PD-L1
|
|
CN113348021B
(zh)
|
2019-01-23 |
2025-07-11 |
武田药品工业株式会社 |
Tyk2抑制剂和其用途
|
|
WO2020165600A1
(en)
|
2019-02-14 |
2020-08-20 |
Bicycletx Limited |
Bicyclic peptide ligand sting conjugates and uses thereof
|
|
CN111620873B
(zh)
*
|
2019-02-28 |
2021-12-28 |
沈阳药科大学 |
一类含哌啶的吡咯并[2,3-d]嘧啶衍生物及其制备和用途
|
|
WO2020181034A1
(en)
|
2019-03-05 |
2020-09-10 |
Incyte Corporation |
Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction
|
|
AU2020235888A1
(en)
|
2019-03-11 |
2021-09-30 |
Nocion Therapeutics, Inc. |
Charged ION channel blockers and methods for use
|
|
US10828287B2
(en)
|
2019-03-11 |
2020-11-10 |
Nocion Therapeutics, Inc. |
Charged ion channel blockers and methods for use
|
|
MX2021010869A
(es)
|
2019-03-11 |
2022-01-19 |
Nocion Therapeutics Inc |
Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso.
|
|
US10934263B2
(en)
|
2019-03-11 |
2021-03-02 |
Nocion Therapeutics, Inc. |
Charged ion channel blockers and methods for use
|
|
US10780083B1
(en)
|
2019-03-11 |
2020-09-22 |
Nocion Therapeutics, Inc. |
Charged ion channel blockers and methods for use
|
|
US11624751B2
(en)
|
2019-03-19 |
2023-04-11 |
Incyte Corporation |
Biomarkers for vitiligo
|
|
EA202192575A1
(ru)
|
2019-03-21 |
2022-01-14 |
Онксео |
Соединения dbait в сочетании с ингибиторами киназ для лечения рака
|
|
SG11202110828UA
(en)
|
2019-04-02 |
2021-10-28 |
Bicycletx Ltd |
Bicycle toxin conjugates and uses thereof
|
|
CN120574283A
(zh)
|
2019-04-05 |
2025-09-02 |
凯麦拉医疗公司 |
Stat降解剂和其用途
|
|
US11548895B2
(en)
|
2019-04-24 |
2023-01-10 |
Elanco Us Inc. |
Process for making crystalline 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile
|
|
CA3138544A1
(en)
|
2019-05-02 |
2020-11-05 |
Aclaris Therapeutics, Inc. |
Substituted pyrrolopyridines as jak inhibitors
|
|
KR102286372B1
(ko)
|
2019-05-27 |
2021-08-05 |
주식회사한국파마 |
Jak 저해제 화합물, 및 이를 포함하는 의약 조성물
|
|
CN110028509B
(zh)
*
|
2019-05-27 |
2020-10-09 |
上海勋和医药科技有限公司 |
作为选择性jak2抑制剂的吡咯并嘧啶类化合物、其合成方法及用途
|
|
AU2020284742B2
(en)
*
|
2019-05-28 |
2026-03-05 |
Mankind Pharma Ltd. |
Novel compounds for inhibition of Janus Kinase 1
|
|
CA3141826A1
(en)
|
2019-05-31 |
2020-12-03 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
JP7532511B2
(ja)
|
2019-06-10 |
2024-08-13 |
インサイト・コーポレイション |
Jak阻害剤による尋常性白斑の局所治療
|
|
WO2020251972A1
(en)
|
2019-06-10 |
2020-12-17 |
Kymera Therapeutics, Inc. |
Smarca degraders and uses thereof
|
|
WO2020261219A1
(en)
|
2019-06-27 |
2020-12-30 |
Crispr Therapeutics Ag |
Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer
|
|
PH12022500002A1
(en)
|
2019-06-28 |
2023-04-03 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
WO2021011868A1
(en)
|
2019-07-17 |
2021-01-21 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
CN110305140B
(zh)
|
2019-07-30 |
2020-08-04 |
上海勋和医药科技有限公司 |
二氢吡咯并嘧啶类选择性jak2抑制剂
|
|
TWI860386B
(zh)
|
2019-07-30 |
2024-11-01 |
英商拜西可泰克斯有限公司 |
異質雙環肽複合物
|
|
US20220235043A1
(en)
*
|
2019-07-31 |
2022-07-28 |
Aclaris Therapeutics, Inc. |
Substituted sulfonamide pyrrolopyridines as jak inhibitors
|
|
WO2021022076A1
(en)
*
|
2019-08-01 |
2021-02-04 |
St. Jude Children's Research Hospital |
Molecules and methods related to treatment of uncontrolled cellular proliferation
|
|
US11845724B2
(en)
|
2019-09-11 |
2023-12-19 |
Vincere Biosciences, Inc. |
USP30 inhibitors and uses thereof
|
|
MX2022002877A
(es)
|
2019-09-13 |
2022-08-08 |
Nimbus Saturn Inc |
Antagonistas de cinasa progenitora hematopoyetica 1 (hpk1) y sus usos.
|
|
WO2021053490A1
(en)
|
2019-09-16 |
2021-03-25 |
Novartis Ag |
Use of high-affinity, ligand-blocking, humanized anti-t-cell immunoglobulin domain and mucin domain-3 (tim-3) igg4 antibody for the treatment of myelofibrosis
|
|
BR112022004225A2
(pt)
|
2019-09-16 |
2022-05-31 |
Novartis Ag |
Uso de um inibidor de mdm2 para o tratamento de mielofibrose
|
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
|
US20220372135A1
(en)
|
2019-09-27 |
2022-11-24 |
Disc Medicine, Inc. |
Methods for treating myelofibrosis and related conditions
|
|
CN110538183B
(zh)
*
|
2019-10-09 |
2021-05-04 |
吉林大学 |
一种预防和治疗小儿湿疹的组合物及其制备方法
|
|
WO2021072098A1
(en)
|
2019-10-10 |
2021-04-15 |
Incyte Corporation |
Biomarkers for graft-versus-host disease
|
|
EP4041204A1
(en)
|
2019-10-10 |
2022-08-17 |
Incyte Corporation |
Biomarkers for graft-versus-host disease
|
|
JP7518900B2
(ja)
|
2019-10-16 |
2024-07-18 |
インサイト・コーポレイション |
皮膚エリテマトーデス及び扁平苔癬(lp)の治療のためのjak1阻害剤の使用
|
|
US11992490B2
(en)
|
2019-10-16 |
2024-05-28 |
Incyte Corporation |
Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
|
|
US11723890B2
(en)
|
2019-11-01 |
2023-08-15 |
Navitor Pharmaceuticals, Inc. |
Methods of treatment using an mTORC1 modulator
|
|
CN114828845A
(zh)
|
2019-11-06 |
2022-07-29 |
诺西恩医疗公司 |
带电的离子通道阻滞剂及其使用方法
|
|
US10933055B1
(en)
|
2019-11-06 |
2021-03-02 |
Nocion Therapeutics, Inc. |
Charged ion channel blockers and methods for use
|
|
CN114761006A
(zh)
|
2019-11-08 |
2022-07-15 |
Inserm(法国国家健康医学研究院) |
对激酶抑制剂产生耐药性的癌症的治疗方法
|
|
JP7717065B2
(ja)
|
2019-11-22 |
2025-08-01 |
インサイト コーポレーション |
Alk2阻害剤及びjak2阻害剤を含む併用療法
|
|
AU2020397938A1
(en)
|
2019-12-05 |
2022-06-23 |
Janssen Pharmaceutica Nv |
Rapamycin analogs and uses thereof
|
|
WO2021119159A1
(en)
|
2019-12-10 |
2021-06-17 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
KR20220145325A
(ko)
|
2019-12-17 |
2022-10-28 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak 분해제 및 이의 용도
|
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
|
EP4081308A4
(en)
|
2019-12-23 |
2024-01-24 |
Kymera Therapeutics, Inc. |
Smarca degraders and uses thereof
|
|
WO2021133917A1
(en)
|
2019-12-23 |
2021-07-01 |
Kymera Therapeutics, Inc. |
Smarca inhibitors and uses thereof
|
|
CN115210229A
(zh)
|
2020-01-03 |
2022-10-18 |
博格有限责任公司 |
多环酰胺作为治疗癌症的ube2k调节剂
|
|
WO2021148581A1
(en)
|
2020-01-22 |
2021-07-29 |
Onxeo |
Novel dbait molecule and its use
|
|
IL295362A
(en)
|
2020-02-05 |
2022-10-01 |
Puretech Lyt Inc |
Lipid drug inhibitors of neurosteroids
|
|
CN111728975A
(zh)
*
|
2020-02-25 |
2020-10-02 |
广东省检迅检测科技有限公司 |
用于减少运动损伤和促进运动损伤修复的组合物
|
|
TW202146393A
(zh)
|
2020-03-03 |
2021-12-16 |
美商皮克醫療公司 |
Eif4e抑制劑及其用途
|
|
WO2021178779A1
(en)
|
2020-03-06 |
2021-09-10 |
Incyte Corporation |
Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors
|
|
US12162851B2
(en)
|
2020-03-11 |
2024-12-10 |
Nocion Therapeutics, Inc. |
Charged ion channel blockers and methods for use
|
|
CN119118953A
(zh)
|
2020-03-11 |
2024-12-13 |
诺西恩医疗公司 |
带电的离子通道阻滞剂及其使用方法
|
|
KR20230005160A
(ko)
|
2020-03-19 |
2023-01-09 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Mdm2 분해제 및 이의 용도
|
|
US11324750B2
(en)
|
2020-04-09 |
2022-05-10 |
Children's Hospital Medical Center |
Compositions and methods for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
|
|
WO2021206766A1
(en)
|
2020-04-09 |
2021-10-14 |
Children's Hospital Medical Center |
Sars-cov-2 infection biomarkers and uses thereof
|
|
EP3892280A3
(en)
|
2020-04-09 |
2022-01-12 |
Children's Hospital Medical Center |
Sars-cov-2 infection biomarkers and uses thereof
|
|
US20230218644A1
(en)
|
2020-04-16 |
2023-07-13 |
Som Innovation Biotech, S.A. |
Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
|
|
KR20230012539A
(ko)
|
2020-05-13 |
2023-01-26 |
디스크 메디슨, 인크. |
골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
|
|
WO2021236139A1
(en)
|
2020-05-21 |
2021-11-25 |
Concert Pharmaceuticals, Inc. |
Novel deuterated jak inhibitor and uses thereof
|
|
MX2022015221A
(es)
|
2020-06-02 |
2023-03-08 |
Incyte Corp |
Procesos para preparar un inhibidor de cinasa jano 1 (jak1).
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
US20230250110A1
(en)
|
2020-06-03 |
2023-08-10 |
Kymera Therapeutics, Inc. |
Deuterated irak degraders and uses thereof
|
|
PT4161528T
(pt)
|
2020-06-03 |
2026-01-23 |
Incyte Corp |
Combinação de ruxolitinib com incb057643 para utilização no tratamento de neoplasias mieloproliferativas
|
|
US11345681B1
(en)
|
2020-06-05 |
2022-05-31 |
Kinnate Biopharma Inc. |
Inhibitors of fibroblast growth factor receptor kinases
|
|
WO2021260657A1
(en)
|
2020-06-26 |
2021-12-30 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19
|
|
EP3944859A1
(en)
|
2020-07-30 |
2022-02-02 |
Assistance Publique Hôpitaux de Paris |
Method for treating immune toxicities induced by immune checkpoint inhibitors
|
|
AU2021322934A1
(en)
|
2020-08-03 |
2023-03-30 |
Bicycletx Limited |
Peptide-based linkers
|
|
US11751108B2
(en)
*
|
2020-08-05 |
2023-09-05 |
Qualcomm Incorporated |
Execution of reduced signaling handover
|
|
CA3194469A1
(en)
*
|
2020-08-12 |
2022-02-17 |
Concert Pharmaceuticals, Inc. |
Process for preparing enantiomerically enriched jak inhibitors
|
|
CA3186504A1
(en)
|
2020-08-17 |
2022-02-24 |
Stephen J. Blakemore |
Bicycle conjugates specific for nectin-4 and uses thereof
|
|
PE20231743A1
(es)
|
2020-08-18 |
2023-10-31 |
Incyte Corp |
Proceso e intermediarios para preparar un inhibidor de jak
|
|
IL300557A
(en)
|
2020-08-18 |
2023-04-01 |
Incyte Corp |
Process and intermediates for preparing a JAK1 inhibitor
|
|
WO2022061351A1
(en)
|
2020-09-16 |
2022-03-24 |
Incyte Corporation |
Topical treatment of vitiligo
|
|
WO2022060094A1
(ko)
*
|
2020-09-16 |
2022-03-24 |
주식회사 엑세쏘바이오파마 |
피리미도 피리미디논 화합물 및 그를 포함하는 약제학적 조성물
|
|
EP4221711A1
(en)
|
2020-10-02 |
2023-08-09 |
Incyte Corporation |
Topical ruxolitinib for treating lichen planus
|
|
EP4225317A1
(en)
|
2020-10-08 |
2023-08-16 |
Novartis AG |
Use of an erk inhibitor for the treatment of myelofibrosis
|
|
EP4225316A1
(en)
|
2020-10-08 |
2023-08-16 |
Novartis AG |
Use of an erk inhibitor for the treatment of myelofibrosis
|
|
US12331046B2
(en)
|
2020-10-23 |
2025-06-17 |
Nimbus Clotho, Inc. |
CTPS1 inhibitors and uses thereof
|
|
CN114437079B
(zh)
*
|
2020-10-30 |
2024-11-01 |
杭州邦顺制药有限公司 |
吡咯嘧啶五元氮杂环化合物的晶型
|
|
KR102551758B1
(ko)
|
2020-11-30 |
2023-07-05 |
주식회사한국파마 |
신규한 jak 특이 저해제 화합물, 및 이의 제조방법
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
CA3200814A1
(en)
|
2020-12-02 |
2022-06-09 |
Alfredo C. Castro |
Tead inhibitors and uses thereof
|
|
HUE071614T2
(hu)
|
2020-12-04 |
2025-09-28 |
Incyte Corp |
JAK-inhibitor D-vitamin-analóggal bõrbetegségek kezelésére
|
|
CA3204374A1
(en)
|
2020-12-08 |
2022-06-16 |
Incyte Corporation |
Jak1 pathway inhibitors for the treatment of vitiligo
|
|
EP4259144A4
(en)
|
2020-12-09 |
2025-08-20 |
Kymera Therapeutics Inc |
SMARCA DEGRADING AGENTS AND THEIR USES
|
|
MX2023007150A
(es)
|
2020-12-18 |
2023-09-04 |
Boehringer Ingelheim Animal Health Usa Inc |
Compuestos de pirazol que contienen boro, composiciones que los comprenden, métodos y usos de los mismos.
|
|
CN116867758A
(zh)
|
2020-12-30 |
2023-10-10 |
凯麦拉医疗公司 |
Irak降解剂和其用途
|
|
TW202237083A
(zh)
|
2021-01-11 |
2022-10-01 |
美商英塞特公司 |
包含jak路徑抑制劑及rock抑制劑之組合療法
|
|
US20240174662A1
(en)
*
|
2021-02-01 |
2024-05-30 |
Janssen Biotech, Inc. |
Small molecule inhibitors of salt inducible kinases
|
|
MX2023009060A
(es)
|
2021-02-02 |
2023-09-29 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 y usos de estos.
|
|
US12378229B2
(en)
|
2021-02-02 |
2025-08-05 |
Liminal Biosciences Limited |
GPR84 antagonists and uses thereof
|
|
WO2022166796A1
(zh)
*
|
2021-02-05 |
2022-08-11 |
上海齐鲁制药研究中心有限公司 |
嘧啶或吡啶并杂环类腺苷受体抑制剂及其制备方法和用途
|
|
EP4291235A4
(en)
|
2021-02-12 |
2025-01-08 |
Nimbus Saturn, Inc. |
HPK1 ANTAGONISTS AND USES THEREOF
|
|
US12171768B2
(en)
|
2021-02-15 |
2024-12-24 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and uses thereof
|
|
CN116867494A
(zh)
|
2021-02-15 |
2023-10-10 |
凯麦拉医疗公司 |
Irak4降解剂和其用途
|
|
MX2023009858A
(es)
|
2021-02-25 |
2023-09-12 |
Impact Biomedicines Inc |
Uso de inhibidores de proteina de bromodominio y motivo extraterminal (bet) solo o en combinacion con fedratinib o ruxolitinib como tratamiento para una malignidad hematologica tal como la mielofibrosis.
|
|
US11926625B2
(en)
|
2021-03-05 |
2024-03-12 |
Nimbus Saturn, Inc. |
HPK1 antagonists and uses thereof
|
|
WO2022213062A1
(en)
|
2021-03-29 |
2022-10-06 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
US12325697B2
(en)
|
2021-04-09 |
2025-06-10 |
Nimbus Clio, Inc. |
CBL-B modulators and uses thereof
|
|
WO2022221866A1
(en)
|
2021-04-16 |
2022-10-20 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
UA129643C2
(uk)
|
2021-05-03 |
2025-06-18 |
Інсайт Корпорейшн |
Інгібітори шляху jak1 для лікування вузлуватого свербця
|
|
KR20240020735A
(ko)
|
2021-05-07 |
2024-02-15 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Cdk2 분해제 및 그 용도
|
|
US12071439B2
(en)
|
2021-07-12 |
2024-08-27 |
Incyte Corporation |
Process and intermediates for preparing a JAK inhibitor
|
|
CA3228505A1
(en)
|
2021-08-11 |
2023-02-16 |
Sun Pharmaceutical Industries, Inc. |
Treatment of hair loss disorders with deuterated jak inhibitors
|
|
CA3229560A1
(en)
|
2021-08-25 |
2023-03-02 |
Christopher L. Vandeusen |
Eif4e inhibitors and uses thereof
|
|
US12157732B2
(en)
|
2021-08-25 |
2024-12-03 |
PIC Therapeutics, Inc. |
eIF4E inhibitors and uses thereof
|
|
KR102718345B1
(ko)
*
|
2021-09-16 |
2024-10-17 |
광주과학기술원 |
신규한 트리아졸릴피롤로피리미딘 유도체 및 이의 용도
|
|
CA3231996A1
(en)
*
|
2021-09-18 |
2023-03-23 |
Satya Srinivas HANUMARA |
An improved process for the preparation of ruxolitinib phosphate
|
|
EP4423086A1
(en)
|
2021-10-25 |
2024-09-04 |
Kymera Therapeutics, Inc. |
Tyk2 degraders and uses thereof
|
|
CA3236265A1
(en)
|
2021-10-29 |
2023-05-04 |
William Leong |
Irak4 degraders and synthesis thereof
|
|
US12290565B2
(en)
|
2021-11-17 |
2025-05-06 |
Altrubio Inc. |
Methods of using anti-PSGL-1 antibodies in combination with JAK inhibitors to treat T-cell mediated inflammatory diseases or cancers
|
|
WO2023102559A1
(en)
|
2021-12-03 |
2023-06-08 |
Incyte Corporation |
Topical formulations of ruxolitinib with an organic amine ph adjusting agent for treatment of skin diseases
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
CN114044777B
(zh)
*
|
2022-01-10 |
2022-04-19 |
南京佰麦生物技术有限公司 |
一种磷酸芦可替尼的制备方法
|
|
CA3243560A1
(en)
|
2022-01-31 |
2023-08-03 |
Kymera Therapeutics, Inc. |
Iraqi Degradation Agents and Their Uses
|
|
CN114456181A
(zh)
*
|
2022-02-21 |
2022-05-10 |
浙江乐普药业股份有限公司 |
一种芦可替尼的制备方法
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
US11878958B2
(en)
|
2022-05-25 |
2024-01-23 |
Ikena Oncology, Inc. |
MEK inhibitors and uses thereof
|
|
AU2023293093A1
(en)
*
|
2022-06-14 |
2025-01-02 |
Incyte Corporation |
Solid forms of a jak inhibitor and process of preparing the same
|
|
CN117384163B
(zh)
*
|
2022-07-05 |
2026-02-17 |
盛世泰科生物医药技术(苏州)股份有限公司 |
一种含偕二氟基的化合物及其制备方法和用途
|
|
KR20250056924A
(ko)
|
2022-08-02 |
2025-04-28 |
리미널 바이오사이언시스 리미티드 |
치환된 피리돈 gpr84 길항제 및 이의 용도
|
|
US20260028330A1
(en)
|
2022-08-02 |
2026-01-29 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
|
IL318577A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND THEIR USES
|
|
WO2024028193A1
(en)
|
2022-08-03 |
2024-02-08 |
Medichem, S.A. |
Stable oral pharmaceutical formulation containing ruxolitinib hemifumarate
|
|
WO2024042448A1
(en)
*
|
2022-08-22 |
2024-02-29 |
Granules India Limited |
An improved process for the preparation of ruxolitinib
|
|
WO2024099396A1
(zh)
*
|
2022-11-11 |
2024-05-16 |
浙江奥翔药业股份有限公司 |
芦可替尼晶体及其药物组合物
|
|
WO2024112894A1
(en)
|
2022-11-22 |
2024-05-30 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
WO2024184926A1
(en)
*
|
2023-03-08 |
2024-09-12 |
Aarti Pharmalabs Limited |
Process for preparation of chiral ruxolitinib and salts thereof
|
|
WO2024187415A1
(en)
*
|
2023-03-15 |
2024-09-19 |
Zhejiang Qizheng Pharmaceutical Co., Ltd. |
Pharmaceutical composition comprising ruxolitinib
|
|
WO2024187416A1
(en)
*
|
2023-03-15 |
2024-09-19 |
Zhejiang Qizheng Pharmaceutical Co., Ltd. |
Pharmaceutical composition comprising ruxolitinib
|
|
WO2024243225A1
(en)
|
2023-05-21 |
2024-11-28 |
Incyte Corporation |
Topical ruxolitinib foam
|
|
AU2024312190A1
(en)
|
2023-06-23 |
2025-07-03 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
EP4491175A1
(en)
|
2023-07-10 |
2025-01-15 |
Genepharm S.A. |
A solid oral composition of ruxolitinib
|
|
CN121194977A
(zh)
|
2023-09-04 |
2025-12-23 |
印度颗粒有限公司 |
用于制备芦可替尼及其新晶型的改良方法
|
|
IT202300018879A1
(it)
|
2023-09-14 |
2025-03-14 |
Chemelectiva S R L |
Processo enzimatico per la preparazione di (r)-3-(4-bromo-1h-pirazol-1-il)-3- ciclopentilpropanenitrile, quale intermedio nella sintesi di ruxolitinib
|
|
AU2024344754A1
(en)
|
2023-09-21 |
2026-04-02 |
Takeda Pharmaceutical Company Limited |
Tyk2 inhibitors for use in the treatment of inflammatory bowel disease
|
|
US12364699B2
(en)
|
2023-10-10 |
2025-07-22 |
Sun Pharmaceuticals Industries, Inc. |
Method of treating hair loss disorders
|
|
WO2025117642A1
(en)
|
2023-12-01 |
2025-06-05 |
Incyte Corporation |
Ruxolitinib for treating hidradenitis suppurativa (hs)
|
|
EP4621803A1
(en)
|
2024-03-22 |
2025-09-24 |
Assistance Publique - Hôpitaux de Paris |
Method for identifying patients in need for ici-induced myotoxicity treatment
|
|
US20260001893A1
(en)
*
|
2024-03-27 |
2026-01-01 |
Gilead Sciences, Inc. |
Small molecule modulators of stat6
|
|
WO2025226637A1
(en)
|
2024-04-22 |
2025-10-30 |
Incyte Corporation |
Combination therapy with an anti-colony stimulating factor 1 receptor antibody and a jak inhibitor
|
|
US20260053743A1
(en)
|
2024-08-26 |
2026-02-26 |
Incyte Corporation |
Topical skin formulations of a pharmaceutically acceptable salt of ruxolitinib
|