JP2022534434A5 - - Google Patents
Info
- Publication number
- JP2022534434A5 JP2022534434A5 JP2021571021A JP2021571021A JP2022534434A5 JP 2022534434 A5 JP2022534434 A5 JP 2022534434A5 JP 2021571021 A JP2021571021 A JP 2021571021A JP 2021571021 A JP2021571021 A JP 2021571021A JP 2022534434 A5 JP2022534434 A5 JP 2022534434A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrimidine
- pyrido
- amine
- methyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19177610 | 2019-05-31 | ||
| EP19177610.3 | 2019-05-31 | ||
| EP19201165.8 | 2019-10-02 | ||
| EP19201165 | 2019-10-02 | ||
| PCT/EP2020/064915 WO2020239953A1 (en) | 2019-05-31 | 2020-05-28 | Pyridopyrimidines derivatives as p2x3 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534434A JP2022534434A (ja) | 2022-07-29 |
| JP2022534434A5 true JP2022534434A5 (https=) | 2023-06-06 |
| JP7797204B2 JP7797204B2 (ja) | 2026-01-13 |
Family
ID=70857198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571021A Active JP7797204B2 (ja) | 2019-05-31 | 2020-05-28 | Ｐ２ｘ３阻害剤としてのピリドピリミジン誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12606562B2 (https=) |
| EP (1) | EP3976609A1 (https=) |
| JP (1) | JP7797204B2 (https=) |
| KR (1) | KR102923602B1 (https=) |
| CN (1) | CN114222741B (https=) |
| AU (1) | AU2020281924B2 (https=) |
| BR (1) | BR112021020279A2 (https=) |
| CA (1) | CA3136024A1 (https=) |
| MA (1) | MA56020A (https=) |
| MX (1) | MX2021014116A (https=) |
| WO (1) | WO2020239953A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3139018A1 (en) | 2019-05-31 | 2020-12-03 | Chiesi Farmaceutici S.P.A. | Amino quinazoline derivatives as p2x3 inhibitors |
| JP7797204B2 (ja) | 2019-05-31 | 2026-01-13 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | Ｐ２ｘ３阻害剤としてのピリドピリミジン誘導体 |
| WO2022160931A1 (zh) * | 2021-01-28 | 2022-08-04 | 浙江海正药业股份有限公司 | 吡啶并嘧啶类衍生物及其制备方法和用途 |
| AR132737A1 (es) | 2023-05-22 | 2025-07-23 | Chiesi Farm Spa | Proceso e intermedios para la preparación de un inhibidor p2x3 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH31122A (en) | 1993-03-31 | 1998-02-23 | Eisai Co Ltd | Nitrogen-containing fused-heterocycle compounds. |
| JP4342007B2 (ja) * | 1998-08-10 | 2009-10-14 | 大日本住友製薬株式会社 | キナゾリン誘導体 |
| CA2557372C (en) | 2004-03-05 | 2013-01-08 | F. Hoffmann-La Roche Ag | Diaminopyrimidines as p2x3 and p2x2/3 antagonists |
| CN101300012B (zh) * | 2005-09-01 | 2011-09-14 | 弗·哈夫曼-拉罗切有限公司 | 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物在制备治疗呼吸系统疾病的药物中的应用 |
| MX2008014689A (es) | 2006-05-23 | 2008-11-27 | Hoffmann La Roche | Derivados de piridopirimidininona. |
| EP2038264B1 (en) | 2006-06-29 | 2016-10-26 | F.Hoffmann-La Roche Ag | Tetrazole-substituted arylamides |
| TW200840584A (en) | 2006-12-26 | 2008-10-16 | Gilead Sciences Inc | Pyrido(3,2-d)pyrimidines useful for treating viral infections |
| EP2136639B1 (en) | 2007-04-02 | 2016-03-09 | Evotec AG | Pyrid-2-yl fused heterocyclic compounds, and compositions and uses thereof |
| PT2139334E (pt) | 2007-04-17 | 2013-10-02 | Evotec Ag | Compostos heterocíclicos fusionados de 2-cianofenilo, e composições e utilizações dos mesmos |
| CA2715835C (en) | 2008-02-29 | 2017-03-21 | Renovis, Inc. | Amide compounds, compositions and uses thereof |
| JP5608655B2 (ja) | 2008-09-18 | 2014-10-15 | エヴォテック アーゲー | Ｐ２ｘ３受容体活性のモジュレーター |
| BRPI0919488A2 (pt) | 2008-09-30 | 2015-12-01 | Astrazeneca Ab | composto, uso de um composto, método para tratar câncer em um animal de sangue quente, composição farmacêutica, e, processo para preparar um composto |
| PL2399910T3 (pl) | 2009-02-13 | 2014-09-30 | Shionogi & Co | Pochodne triazyny jako antagoniści receptora p2x3 i/albo p2x2/3 i kompozycja farmaceutyczna zawierająca je |
| WO2011041655A1 (en) * | 2009-10-01 | 2011-04-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Quinazolin-4-amine derivatives; and methods of use |
| JP2013545749A (ja) | 2010-11-10 | 2013-12-26 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 複素環化合物及びその使用 |
| KR101685862B1 (ko) | 2012-12-27 | 2016-12-20 | 에프. 호프만-라 로슈 아게 | Comt 억제제 |
| WO2016053794A1 (en) | 2014-09-30 | 2016-04-07 | Bristol-Myers Squibb Company | Quinazoline-based kinase inhibitors |
| JPWO2016084922A1 (ja) | 2014-11-28 | 2017-09-07 | 塩野義製薬株式会社 | １，２，４−トリアジン誘導体およびその医薬組成物 |
| WO2016088838A1 (ja) | 2014-12-04 | 2016-06-09 | 塩野義製薬株式会社 | プリン誘導体およびその医薬組成物 |
| EP3230281B1 (en) | 2014-12-09 | 2021-05-26 | Bayer Aktiengesellschaft | 1,3-thiazol-2-yl substituted benzamides |
| WO2017011729A1 (en) | 2015-07-16 | 2017-01-19 | Patara Pharma, LLC | Combination therapies for the treatment of lung diseases |
| DK3355889T3 (da) | 2015-09-29 | 2023-05-15 | Afferent Pharmaceuticals Inc | Diaminopyrimidin-p2x3- og p2x2/3-receptormodulatorer til anvendelse i behandling af hoste |
| JP6882289B2 (ja) * | 2015-11-25 | 2021-06-02 | コンバージーン・リミテッド・ライアビリティ・カンパニーＣｏｎｖｅｒｇｅｎｅ Ｌｌｃ | 二環式ｂｅｔブロモドメイン阻害剤及びその使用 |
| CN106565684B (zh) | 2016-03-18 | 2019-06-18 | 南方医科大学 | 6-吡唑取代喹唑啉类化合物及其衍生物、合成方法及其应用 |
| CA3029457A1 (en) | 2016-06-30 | 2018-01-04 | Gilead Sciences, Inc. | 4,6-diaminoquinazolines as cot modulators and methods of use thereof |
| GB201700814D0 (en) | 2017-01-17 | 2017-03-01 | Liverpool School Tropical Medicine | Compounds |
| US11000491B2 (en) | 2017-05-05 | 2021-05-11 | Hepanova, Inc. | Amino-aryl-benzamide compounds and methods of use thereof |
| RS63661B1 (sr) * | 2018-07-25 | 2022-11-30 | Faes Farma Sa | Piridopirimidini kao inhibitori histaminskog h4-receptora |
| CN109721554A (zh) | 2019-01-08 | 2019-05-07 | 贵州大学 | 一类4-氨基喹唑啉类化合物及其制备方法和应用 |
| JP7797204B2 (ja) | 2019-05-31 | 2026-01-13 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | Ｐ２ｘ３阻害剤としてのピリドピリミジン誘導体 |
| CA3139018A1 (en) | 2019-05-31 | 2020-12-03 | Chiesi Farmaceutici S.P.A. | Amino quinazoline derivatives as p2x3 inhibitors |
-
2020
- 2020-05-28 JP JP2021571021A patent/JP7797204B2/ja active Active
- 2020-05-28 CA CA3136024A patent/CA3136024A1/en active Pending
- 2020-05-28 WO PCT/EP2020/064915 patent/WO2020239953A1/en not_active Ceased
- 2020-05-28 BR BR112021020279A patent/BR112021020279A2/pt unknown
- 2020-05-28 US US17/615,012 patent/US12606562B2/en active Active
- 2020-05-28 MX MX2021014116A patent/MX2021014116A/es unknown
- 2020-05-28 CN CN202080038831.1A patent/CN114222741B/zh active Active
- 2020-05-28 AU AU2020281924A patent/AU2020281924B2/en active Active
- 2020-05-28 KR KR1020217038473A patent/KR102923602B1/ko active Active
- 2020-05-28 MA MA056020A patent/MA56020A/fr unknown
- 2020-05-28 EP EP20728500.8A patent/EP3976609A1/en active Pending
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