JP2020511452A5 - - Google Patents
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- Publication number
- JP2020511452A5 JP2020511452A5 JP2019548905A JP2019548905A JP2020511452A5 JP 2020511452 A5 JP2020511452 A5 JP 2020511452A5 JP 2019548905 A JP2019548905 A JP 2019548905A JP 2019548905 A JP2019548905 A JP 2019548905A JP 2020511452 A5 JP2020511452 A5 JP 2020511452A5
- Authority
- JP
- Japan
- Prior art keywords
- fluoro
- pyridine
- aminopiperidine
- benzodiazole
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762472480P | 2017-03-16 | 2017-03-16 | |
| US62/472,480 | 2017-03-16 | ||
| PCT/US2018/022665 WO2018170284A1 (en) | 2017-03-16 | 2018-03-15 | Somatostatin modulators and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020511452A JP2020511452A (ja) | 2020-04-16 |
| JP2020511452A5 true JP2020511452A5 (https=) | 2022-06-23 |
| JP7106564B2 JP7106564B2 (ja) | 2022-07-26 |
Family
ID=63523267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548905A Active JP7106564B2 (ja) | 2017-03-16 | 2018-03-15 | ソマトスタチンモジュレータとその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US11072598B2 (https=) |
| EP (1) | EP3596062A4 (https=) |
| JP (1) | JP7106564B2 (https=) |
| KR (1) | KR20190121404A (https=) |
| CN (1) | CN110650951B (https=) |
| AU (1) | AU2018234806A1 (https=) |
| BR (1) | BR112019019168A2 (https=) |
| CA (1) | CA3056131A1 (https=) |
| EA (1) | EA201992083A1 (https=) |
| IL (1) | IL269241B (https=) |
| MX (1) | MX2019010949A (https=) |
| NZ (1) | NZ757081A (https=) |
| SG (1) | SG11201908512YA (https=) |
| TW (1) | TW201840550A (https=) |
| UA (1) | UA127346C2 (https=) |
| WO (1) | WO2018170284A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3596062A4 (en) | 2017-03-16 | 2020-08-26 | Crinetics Pharmaceuticals, Inc. | SOMATOSTATIN MODULATORS AND THEIR USES |
| MA51840A (fr) | 2018-02-12 | 2021-05-19 | Crinetics Pharmaceuticals Inc | Modulateurs de somatostatine et leurs utilisations |
| WO2019240246A1 (ja) * | 2018-06-15 | 2019-12-19 | 小野薬品工業株式会社 | ピペリジノール誘導体の新規な塩および新規結晶形 |
| SMT202500155T1 (it) | 2018-09-18 | 2025-05-12 | Crinetics Pharmaceuticals Inc | Modulatori della somatostatina e loro usi |
| TWI841768B (zh) | 2019-08-14 | 2024-05-11 | 美商克林提克斯醫藥股份有限公司 | 非肽生長抑制素(somatostatin)5型受體激動劑及其用途 |
| WO2021076448A1 (en) * | 2019-10-14 | 2021-04-22 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators for treating pituitary adenomas |
| US12509444B2 (en) * | 2019-12-06 | 2025-12-30 | Plexxikon Inc. | Compounds and methods for CD73 modulation and indications therefor |
| AR121682A1 (es) | 2020-03-31 | 2022-06-29 | Takeda Pharmaceuticals Co | Derivados de n-(heterociclil y heterociclilalquil)-3-bencilpiridin-2-amina como agonistas de sstr4 |
| CA3191084A1 (en) | 2020-09-09 | 2022-03-17 | Gerald Burke | Formulations of a somatostatin modulator |
| JP2024506715A (ja) | 2021-02-17 | 2024-02-14 | クリネティックス ファーマシューティカルズ，インク． | ソマトスタチンモジュレーターの結晶形態 |
| CN117377495A (zh) * | 2021-06-09 | 2024-01-09 | 克林提克斯医药股份有限公司 | 非肽靶向治疗剂及其用途 |
| CN114591326B (zh) * | 2022-02-28 | 2024-02-27 | 上海筛杰生物医药有限公司 | Cct-251921的中间体及其制备方法 |
| IL320483A (en) * | 2022-10-28 | 2025-06-01 | Basecamp Bio Inc | Somatostatin receptor 2 agonists and uses thereof |
| TW202440164A (zh) * | 2022-12-13 | 2024-10-16 | 美商克林提克斯醫藥股份有限公司 | 生長抑素亞型-2受體（sst2r）靶向治療劑及其用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127343A (en) | 1996-05-14 | 2000-10-03 | Novo Nordisk A/S | Somatostatin agonists and antagonists |
| US6025372A (en) | 1997-04-04 | 2000-02-15 | Merck & Co., Inc. | Somatostatin agonists |
| FR2802206B1 (fr) * | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
| US20060281764A1 (en) * | 2005-06-10 | 2006-12-14 | Gaul Michael D | Aminopyrimidines as kinase modulators |
| AU2007309708A1 (en) | 2006-03-13 | 2008-05-02 | Merck Sharp & Dohme Corp. | Somatostatin agonists |
| WO2008019967A2 (en) | 2006-08-15 | 2008-02-21 | F. Hoffmann-La Roche Ag | Phenyl, pyridine and quinoline derivatives |
| WO2009051705A1 (en) | 2007-10-18 | 2009-04-23 | Merck & Co., Inc. | Substituted 1,2,4-oxadiazoles and analogs thereof as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases |
| JP2011526294A (ja) | 2008-06-25 | 2011-10-06 | エンビボ ファーマシューティカルズ インコーポレイテッド | ホスホジエステラーゼ１０阻害剤としての二置換フェニル化合物 |
| GB0818241D0 (en) | 2008-10-06 | 2008-11-12 | Cancer Res Technology | Compounds and their use |
| JP2013503846A (ja) | 2009-09-01 | 2013-02-04 | ファイザー・インク | ベンズイミダゾール誘導体 |
| AU2011256444B2 (en) | 2010-05-18 | 2014-07-10 | Merck Sharp & Dohme Corp. | Spiro isoxazoline compounds as SSTR5 antagonists |
| GB201008290D0 (en) | 2010-05-18 | 2010-06-30 | Syngenta Ltd | Chemical compounds |
| WO2014007228A1 (ja) | 2012-07-03 | 2014-01-09 | 小野薬品工業株式会社 | ソマトスタチン受容体作動活性を有する化合物およびその医薬用途 |
| US9643951B2 (en) | 2013-09-30 | 2017-05-09 | Ono Pharmaceutical Co., Ltd. | Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof |
| ES2675504T3 (es) | 2013-10-02 | 2018-07-11 | Kuraray Co., Ltd. | Composición de resina, lámina de múltiples capas, material de envasado y recipiente |
| IL264178B2 (en) | 2016-07-14 | 2024-05-01 | Crinetics Pharmaceuticals Inc | Somatostatin modulators and uses thereof |
| AU2018219644A1 (en) | 2017-02-08 | 2019-08-29 | Ono Pharmaceutical Co., Ltd. | Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof |
| EP3596062A4 (en) | 2017-03-16 | 2020-08-26 | Crinetics Pharmaceuticals, Inc. | SOMATOSTATIN MODULATORS AND THEIR USES |
| EP3658560A4 (en) | 2017-07-25 | 2021-01-06 | Crinetics Pharmaceuticals, Inc. | SOMATOSTAT IN MODULATORS AND USES THEREOF |
| MA51840A (fr) | 2018-02-12 | 2021-05-19 | Crinetics Pharmaceuticals Inc | Modulateurs de somatostatine et leurs utilisations |
| SMT202500155T1 (it) | 2018-09-18 | 2025-05-12 | Crinetics Pharmaceuticals Inc | Modulatori della somatostatina e loro usi |
-
2018
- 2018-03-15 EP EP18767082.3A patent/EP3596062A4/en active Pending
- 2018-03-15 NZ NZ757081A patent/NZ757081A/en unknown
- 2018-03-15 KR KR1020197030515A patent/KR20190121404A/ko not_active Withdrawn
- 2018-03-15 IL IL269241A patent/IL269241B/en unknown
- 2018-03-15 SG SG11201908512Y patent/SG11201908512YA/en unknown
- 2018-03-15 UA UAA201910112A patent/UA127346C2/uk unknown
- 2018-03-15 BR BR112019019168A patent/BR112019019168A2/pt not_active Application Discontinuation
- 2018-03-15 MX MX2019010949A patent/MX2019010949A/es unknown
- 2018-03-15 WO PCT/US2018/022665 patent/WO2018170284A1/en not_active Ceased
- 2018-03-15 EA EA201992083A patent/EA201992083A1/ru unknown
- 2018-03-15 CA CA3056131A patent/CA3056131A1/en not_active Abandoned
- 2018-03-15 AU AU2018234806A patent/AU2018234806A1/en not_active Abandoned
- 2018-03-15 CN CN201880033113.8A patent/CN110650951B/zh active Active
- 2018-03-15 JP JP2019548905A patent/JP7106564B2/ja active Active
- 2018-03-16 TW TW107109163A patent/TW201840550A/zh unknown
-
2019
- 2019-09-16 US US16/572,453 patent/US11072598B2/en active Active