JP2024528036A5 - - Google Patents
Info
- Publication number
- JP2024528036A5 JP2024528036A5 JP2024505223A JP2024505223A JP2024528036A5 JP 2024528036 A5 JP2024528036 A5 JP 2024528036A5 JP 2024505223 A JP2024505223 A JP 2024505223A JP 2024505223 A JP2024505223 A JP 2024505223A JP 2024528036 A5 JP2024528036 A5 JP 2024528036A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163226557P | 2021-07-28 | 2021-07-28 | |
| US63/226,557 | 2021-07-28 | ||
| US202263305103P | 2022-01-31 | 2022-01-31 | |
| US63/305,103 | 2022-01-31 | ||
| US202263368034P | 2022-07-08 | 2022-07-08 | |
| US63/368,034 | 2022-07-08 | ||
| PCT/US2022/038577 WO2023009663A1 (en) | 2021-07-28 | 2022-07-27 | Substituted pyridine derivatives as sarm1 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024528036A JP2024528036A (ja) | 2024-07-26 |
| JP2024528036A5 true JP2024528036A5 (https=) | 2025-07-14 |
| JPWO2023009663A5 JPWO2023009663A5 (https=) | 2025-07-14 |
Family
ID=85087993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024505223A Pending JP2024528036A (ja) | 2021-07-28 | 2022-07-27 | Sarm1阻害剤としての置換ピリジン誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11629136B1 (https=) |
| EP (1) | EP4376840A4 (https=) |
| JP (1) | JP2024528036A (https=) |
| KR (1) | KR20240041987A (https=) |
| AU (1) | AU2022320699A1 (https=) |
| CA (1) | CA3226869A1 (https=) |
| CL (1) | CL2024000239A1 (https=) |
| CO (1) | CO2024001716A2 (https=) |
| IL (1) | IL310403A (https=) |
| MX (1) | MX2024001322A (https=) |
| TW (1) | TW202313009A (https=) |
| WO (1) | WO2023009663A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4192828A1 (en) | 2020-08-04 | 2023-06-14 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| CN116438171A (zh) | 2020-09-16 | 2023-07-14 | 努拉生物公司 | 作为sarm1抑制剂的取代的吡啶衍生物 |
| US20240208923A1 (en) | 2021-03-10 | 2024-06-27 | Jnana Therapeutics Inc. | Small molecule inhibitors of mammalian slc6a19 function |
| CN113655155A (zh) * | 2021-07-28 | 2021-11-16 | 任贤金 | 一种测定sph3127有关物质的方法 |
| MX2024001322A (es) | 2021-07-28 | 2024-04-30 | Nura Bio Inc | Derivados de piridina sustituida como inhibidores de sarm1. |
| EP4562001A1 (en) * | 2022-07-27 | 2025-06-04 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| CN120424050A (zh) * | 2024-02-05 | 2025-08-05 | 科辉智药(深圳)新药研究中心有限公司 | 作为sarm1酶活性抑制剂的吡啶类化合物及其应用 |
| WO2025179205A1 (en) * | 2024-02-23 | 2025-08-28 | Nura Bio, Inc. | Methods for the treatment of neurological disorders |
| WO2026080488A1 (en) | 2024-10-09 | 2026-04-16 | Genentech, Inc. | Heterocyclic compounds for the treatment of neurodegenerative diseases |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999018096A1 (en) | 1997-10-02 | 1999-04-15 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| WO2003022274A2 (en) | 2001-09-13 | 2003-03-20 | Synta Pharmaceuticals Corp. | 2-aroylimidazole compounds for treating cancer |
| DE102004009933A1 (de) | 2004-02-26 | 2005-09-15 | Merck Patent Gmbh | Verwendung von Thiadiazolharnstoffderivaten |
| US7531556B2 (en) | 2004-04-28 | 2009-05-12 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of rock and other protein kinases |
| PE20060426A1 (es) * | 2004-06-02 | 2006-06-28 | Schering Corp | DERIVADOS DE ACIDO TARTARICO COMO INHIBIDORES DE MMPs, ADAMs, TACE Y TNF-alfa |
| EP2197849B1 (en) | 2007-10-09 | 2013-02-27 | Merck Patent GmbH | N- ( pyrazole- 3 -yl) -benzamide derivatives as glucokinase activators |
| US20110105436A1 (en) | 2008-03-10 | 2011-05-05 | Auckland Uniservices Limited | Heteroaryl compounds, compositions, and methods of use in cancer treatment |
| WO2010093849A2 (en) | 2009-02-13 | 2010-08-19 | Amgen Inc. | Phenylalanine amide derivatives useful for treating insulin-related diseases and conditions |
| ES2532703T3 (es) | 2010-10-13 | 2015-03-31 | Glaxo Group Limited | Derivados de 3-amino-pirazol útiles contra la tuberculosis |
| JP2012102088A (ja) | 2010-10-14 | 2012-05-31 | Sumitomo Chemical Co Ltd | ヘテロ芳香環化合物およびその有害生物防除用途 |
| MX370188B (es) | 2013-03-14 | 2019-12-04 | Dart Neuroscience Cayman Ltd | Compuestos de piridina y pirazina sustituidos como inhibidores de pde4. |
| AR096393A1 (es) | 2013-05-23 | 2015-12-30 | Bayer Cropscience Ag | Compuestos heterocíclicos pesticidas |
| WO2015140130A1 (en) | 2014-03-17 | 2015-09-24 | Remynd Nv | Oxadiazole compounds |
| WO2015175704A1 (en) | 2014-05-14 | 2015-11-19 | The Regents Of The University Of California | Inhibitors of bacterial dna gyrase with efficacy against gram-negative bacteria |
| WO2016012474A1 (en) | 2014-07-24 | 2016-01-28 | Bayer Pharma Aktiengesellschaft | Glucose transport inhibitors |
| HK1248070A1 (zh) | 2015-05-18 | 2018-10-12 | 转化药物开发有限责任公司 | 作为激酶抑制剂的杂环化合物 |
| US20170355708A1 (en) | 2016-06-09 | 2017-12-14 | Cadent Therapeutics, Inc. | Potassium channel modulators |
| US10807966B2 (en) | 2016-11-21 | 2020-10-20 | Translational Drug Development, Llc | Heterocyclic compounds as kinase inhibitors |
| JP7481329B2 (ja) | 2018-06-07 | 2024-05-10 | ディスアーム セラピューティクス, インコーポレイテッド | Sarm1阻害剤 |
| CA3131930A1 (en) | 2019-02-28 | 2020-09-03 | Kezar Life Sciences | Thiazole derivatives as protein secretion inhibitors |
| EP3980011B1 (en) | 2019-06-06 | 2025-12-17 | Disarm Therapeutics, Inc. | Inhibitors of sarm1 |
| CA3141404A1 (en) * | 2019-06-14 | 2020-12-17 | Disarm Therapeutics, Inc. | Inhibitors of sarm1 |
| JP7534390B2 (ja) * | 2019-09-12 | 2024-08-14 | ディスアーム セラピューティクス, インコーポレイテッド | Sarm1の阻害剤 |
| CR20220375A (es) * | 2020-01-07 | 2022-09-22 | Disarm Therapeutics Inc | Inhibidores de sarm1 |
| CN115916764B (zh) | 2020-04-09 | 2024-09-20 | 达萨玛治疗公司 | 作为sarm1抑制剂的吲唑衍生物 |
| EP4192828A1 (en) | 2020-08-04 | 2023-06-14 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| TW202334117A (zh) | 2020-08-24 | 2023-09-01 | 美商達薩瑪治療公司 | Sarm1之抑制劑 |
| CN116438171A (zh) | 2020-09-16 | 2023-07-14 | 努拉生物公司 | 作为sarm1抑制剂的取代的吡啶衍生物 |
| MX2024001322A (es) | 2021-07-28 | 2024-04-30 | Nura Bio Inc | Derivados de piridina sustituida como inhibidores de sarm1. |
| EP4562001A1 (en) | 2022-07-27 | 2025-06-04 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
-
2022
- 2022-07-27 MX MX2024001322A patent/MX2024001322A/es unknown
- 2022-07-27 WO PCT/US2022/038577 patent/WO2023009663A1/en not_active Ceased
- 2022-07-27 JP JP2024505223A patent/JP2024528036A/ja active Pending
- 2022-07-27 IL IL310403A patent/IL310403A/en unknown
- 2022-07-27 US US17/875,301 patent/US11629136B1/en active Active
- 2022-07-27 AU AU2022320699A patent/AU2022320699A1/en active Pending
- 2022-07-27 KR KR1020247006685A patent/KR20240041987A/ko active Pending
- 2022-07-27 EP EP22850281.1A patent/EP4376840A4/en active Pending
- 2022-07-27 CA CA3226869A patent/CA3226869A1/en active Pending
- 2022-07-27 TW TW111128145A patent/TW202313009A/zh unknown
-
2023
- 2023-03-03 US US18/178,325 patent/US12110285B2/en active Active
-
2024
- 2024-01-26 CL CL2024000239A patent/CL2024000239A1/es unknown
- 2024-02-19 CO CONC2024/0001716A patent/CO2024001716A2/es unknown