JP2022511477A5 - - Google Patents
Info
- Publication number
- JP2022511477A5 JP2022511477A5 JP2021531523A JP2021531523A JP2022511477A5 JP 2022511477 A5 JP2022511477 A5 JP 2022511477A5 JP 2021531523 A JP2021531523 A JP 2021531523A JP 2021531523 A JP2021531523 A JP 2021531523A JP 2022511477 A5 JP2022511477 A5 JP 2022511477A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862774794P | 2018-12-03 | 2018-12-03 | |
| US62/774,794 | 2018-12-03 | ||
| PCT/US2019/063921 WO2020117635A1 (en) | 2018-12-03 | 2019-12-02 | Ire1 small molecule inhibitors |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022511477A JP2022511477A (ja) | 2022-01-31 |
| JPWO2020117635A5 JPWO2020117635A5 (https=) | 2022-12-02 |
| JP2022511477A5 true JP2022511477A5 (https=) | 2022-12-02 |
| JP7546299B2 JP7546299B2 (ja) | 2024-09-06 |
Family
ID=69024615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531523A Active JP7546299B2 (ja) | 2018-12-03 | 2019-12-02 | Ｉｒｅ１小分子阻害物質 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12071426B2 (https=) |
| EP (1) | EP3891137B1 (https=) |
| JP (1) | JP7546299B2 (https=) |
| AU (1) | AU2019393754A1 (https=) |
| CA (1) | CA3121755A1 (https=) |
| IL (1) | IL283433A (https=) |
| SG (1) | SG11202105690TA (https=) |
| WO (1) | WO2020117635A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI831829B (zh) | 2018-09-12 | 2024-02-11 | 美商建南德克公司 | 苯氧基-吡啶基-嘧啶化合物及使用方法 |
| EP3891137B1 (en) | 2018-12-03 | 2024-10-09 | Cornell University | Ire1 small molecule inhibitors |
| JP7539892B2 (ja) | 2019-01-03 | 2024-08-26 | ジェネンテック， インコーポレイテッド | 癌疾患の処置のためのエンドリボヌクレアーゼのイノシトール要求酵素ｉ（ｉｒｅｉアルファ）の阻害剤としてのピリド－ピリミジノン化合物及びプテリジノン化合物 |
| CN113795307A (zh) * | 2019-02-18 | 2021-12-14 | 基因泰克公司 | 吡啶并嘧啶基化合物及其使用方法 |
| WO2020232403A1 (en) * | 2019-05-15 | 2020-11-19 | Cornell University | Treatment of fibrosis with ire1 small molecule inhibitors |
| WO2020252165A1 (en) * | 2019-06-11 | 2020-12-17 | Genentech, Inc. | Quinazolinyl compounds and methods of use |
| US11840523B2 (en) * | 2020-11-13 | 2023-12-12 | The Regents Of The University Of California | IRE1α inhibitors and uses thereof |
| MX2023005747A (es) | 2020-11-18 | 2023-07-28 | Deciphera Pharmaceuticals Llc | Inhibidores de gcn2 y perk quinasas y metodos de uso de los mismos. |
| KR20240113496A (ko) | 2021-12-03 | 2024-07-22 | 데시페라 파마슈티칼스, 엘엘씨. | Gcn2 및 perk 키나아제 억제제로서의 헤테로고리 화합물 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8664230B2 (en) * | 2011-03-17 | 2014-03-04 | The Asan Foundation | Pyridopyrimidine derivatives and use thereof |
| EP3548476A4 (en) * | 2016-12-02 | 2020-05-20 | Quentis Therapeutics, Inc. | SMALL MOLECULAR IRE1 INHIBITORS |
| CN108239074B (zh) | 2016-12-26 | 2021-07-06 | 中国医学科学院药物研究所 | 喹唑啉类化合物及其制备方法、用途和药物组合物 |
| AR111281A1 (es) * | 2017-03-17 | 2019-06-26 | Genentech Inc | Compuestos de pirimidinil-piridiloxi-naftil y métodos para tratar enfermedades y trastornos relacionados con ire1 |
| CA3064837A1 (en) * | 2017-06-01 | 2018-12-06 | Quentis Therapeutics, Inc. | Ire1 small molecule inhibitors |
| US10745379B2 (en) * | 2017-11-10 | 2020-08-18 | Cornell University | IRE1 small molecule inhibitors |
| EP3891137B1 (en) | 2018-12-03 | 2024-10-09 | Cornell University | Ire1 small molecule inhibitors |
-
2019
- 2019-12-02 EP EP19828388.9A patent/EP3891137B1/en active Active
- 2019-12-02 US US17/299,684 patent/US12071426B2/en active Active
- 2019-12-02 AU AU2019393754A patent/AU2019393754A1/en not_active Abandoned
- 2019-12-02 JP JP2021531523A patent/JP7546299B2/ja active Active
- 2019-12-02 CA CA3121755A patent/CA3121755A1/en not_active Abandoned
- 2019-12-02 WO PCT/US2019/063921 patent/WO2020117635A1/en not_active Ceased
- 2019-12-02 SG SG11202105690TA patent/SG11202105690TA/en unknown
-
2021
- 2021-05-25 IL IL283433A patent/IL283433A/en unknown