JP2023542541A5 - - Google Patents
Info
- Publication number
- JP2023542541A5 JP2023542541A5 JP2023518858A JP2023518858A JP2023542541A5 JP 2023542541 A5 JP2023542541 A5 JP 2023542541A5 JP 2023518858 A JP2023518858 A JP 2023518858A JP 2023518858 A JP2023518858 A JP 2023518858A JP 2023542541 A5 JP2023542541 A5 JP 2023542541A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- heterocyclyl
- aryl
- cycloalkyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063083638P | 2020-09-25 | 2020-09-25 | |
| US63/083,638 | 2020-09-25 | ||
| US202163145407P | 2021-02-03 | 2021-02-03 | |
| US63/145,407 | 2021-02-03 | ||
| US202163211987P | 2021-06-17 | 2021-06-17 | |
| US63/211,987 | 2021-06-17 | ||
| PCT/US2021/052044 WO2022067094A1 (en) | 2020-09-25 | 2021-09-24 | Modulators of mas-related g-protein receptor x2 and related products and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023542541A JP2023542541A (ja) | 2023-10-10 |
| JP2023542541A5 true JP2023542541A5 (https=) | 2024-10-02 |
Family
ID=78302949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023518858A Pending JP2023542541A (ja) | 2020-09-25 | 2021-09-24 | Ｍａｓ関連ｇタンパク質受容体ｘ２のモジュレーター、並びに関連製品及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11919864B2 (https=) |
| EP (1) | EP4217345A1 (https=) |
| JP (1) | JP2023542541A (https=) |
| KR (1) | KR20230097015A (https=) |
| CN (1) | CN116406357A (https=) |
| AU (1) | AU2021347360A1 (https=) |
| CA (1) | CA3193207A1 (https=) |
| IL (1) | IL301575A (https=) |
| MX (1) | MX2023003476A (https=) |
| WO (1) | WO2022067094A1 (https=) |
| ZA (1) | ZA202304729B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023003476A (es) * | 2020-09-25 | 2023-06-22 | Escient Pharmaceuticals Inc | Moduladores del receptor x2 de proteína g relacionado con mas y productos y métodos relacionados. |
| US11970452B2 (en) * | 2020-10-21 | 2024-04-30 | Escient Pharmaceuticals, Inc. | Modulators of mas-related G-protein receptor X2 and related products and methods |
| CR20240463A (es) | 2022-03-30 | 2025-02-05 | Escient Pharmaceuticals Inc | Derivados de quinolina como moduladores del receptor x2 de la proteína g relacionados con mas y productos relacionados |
| CN115850250B (zh) * | 2022-10-25 | 2025-12-23 | 南京师范大学 | 一种可控可视化的一氧化碳释放剂及其制备方法和应用 |
| CN121532382A (zh) * | 2023-07-13 | 2026-02-13 | 北京普祺医药科技股份有限公司 | Mas相关g蛋白受体x2的拮抗剂及其用途 |
| WO2025042736A1 (en) | 2023-08-18 | 2025-02-27 | Incyte Corporation | Bicyclic heterocycles as mrgprx2 antagonists |
| CN119504738A (zh) * | 2023-08-25 | 2025-02-25 | 武汉人福创新药物研发中心有限公司 | 作为mrgprx2拮抗剂的化合物及其制备方法和应用 |
| WO2025119372A2 (zh) * | 2023-12-08 | 2025-06-12 | 武汉人福创新药物研发中心有限公司 | Mrgprx2拮抗剂及用途 |
| WO2025153014A1 (zh) * | 2024-01-17 | 2025-07-24 | 武汉人福创新药物研发中心有限公司 | Mas相关g蛋白受体x2拮抗剂及用途 |
| WO2025160430A1 (en) | 2024-01-25 | 2025-07-31 | Incyte Corporation | Bicyclic heterocycles as mrgprx2 antagonists |
| WO2025222040A1 (en) | 2024-04-19 | 2025-10-23 | Escient Pharmaceuticals, Inc. | Mrgprx2 modulators for use in treating mrgprx2 dependent conditions in subjects with low ige |
| WO2025223036A1 (zh) * | 2024-04-23 | 2025-10-30 | 凯复(苏州)生物医药有限公司 | Mrgprx2拮抗剂、包含其的药物组合物及其用途 |
| WO2025264860A2 (en) | 2024-06-18 | 2025-12-26 | Yale University | Methods of treating post-covid airway disease |
| JP2026009006A (ja) * | 2024-07-01 | 2026-01-19 | 日本たばこ産業株式会社 | ピリダジノン化合物及びその医薬用途 |
| WO2026037254A1 (zh) * | 2024-08-10 | 2026-02-19 | 杭州英创医药科技有限公司 | 作为mrgprx2拮抗剂的化合物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1509184A (zh) * | 2001-03-19 | 2004-06-30 | �ձ���ҩ��ʽ���� | 止痒剂 |
| AU2002331621B2 (en) * | 2001-08-15 | 2008-06-05 | Icos Corporation | 2H-phthalazin-1-ones and methods for use thereof |
| WO2004078114A2 (en) * | 2003-02-28 | 2004-09-16 | Encysive Pharmaceuticals Inc. | Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-ii receptor antagonists. |
| US7320989B2 (en) * | 2003-02-28 | 2008-01-22 | Encysive Pharmaceuticals, Inc. | Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists |
| EP1706384A1 (en) * | 2004-01-07 | 2006-10-04 | AstraZeneca AB | Therapeutic agents i |
| JP2006124387A (ja) * | 2004-09-30 | 2006-05-18 | Taisho Pharmaceut Co Ltd | 新規なキノリン、テトラヒドロキナゾリン、及びピリミジン誘導体と、これらを使用することに関連した治療方法 |
| CN102625799A (zh) * | 2009-06-25 | 2012-08-01 | 安姆根有限公司 | 杂环化合物及其用途 |
| PH12014500888A1 (en) * | 2011-11-08 | 2014-06-09 | Arena Pharm Inc | Modulators of the g protein-coupled mas receptor and the treatment of disorders related thereto |
| WO2014120995A2 (en) * | 2013-02-01 | 2014-08-07 | Wellstat Therapeutics Corporation | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity |
| MX2023003476A (es) * | 2020-09-25 | 2023-06-22 | Escient Pharmaceuticals Inc | Moduladores del receptor x2 de proteína g relacionado con mas y productos y métodos relacionados. |
-
2021
- 2021-09-24 MX MX2023003476A patent/MX2023003476A/es unknown
- 2021-09-24 CN CN202180075369.7A patent/CN116406357A/zh active Pending
- 2021-09-24 WO PCT/US2021/052044 patent/WO2022067094A1/en not_active Ceased
- 2021-09-24 EP EP21795105.2A patent/EP4217345A1/en active Pending
- 2021-09-24 AU AU2021347360A patent/AU2021347360A1/en active Pending
- 2021-09-24 JP JP2023518858A patent/JP2023542541A/ja active Pending
- 2021-09-24 IL IL301575A patent/IL301575A/en unknown
- 2021-09-24 CA CA3193207A patent/CA3193207A1/en active Pending
- 2021-09-24 KR KR1020237013945A patent/KR20230097015A/ko not_active Ceased
- 2021-09-24 US US17/484,993 patent/US11919864B2/en active Active
-
2023
- 2023-04-24 ZA ZA2023/04729A patent/ZA202304729B/en unknown
- 2023-11-30 US US18/525,253 patent/US12275707B2/en active Active