JP2023542541A5 - - Google Patents

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Publication number
JP2023542541A5
JP2023542541A5 JP2023518858A JP2023518858A JP2023542541A5 JP 2023542541 A5 JP2023542541 A5 JP 2023542541A5 JP 2023518858 A JP2023518858 A JP 2023518858A JP 2023518858 A JP2023518858 A JP 2023518858A JP 2023542541 A5 JP2023542541 A5 JP 2023542541A5
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JP
Japan
Application number
JP2023518858A
Other languages
Japanese (ja)
Other versions
JPWO2022067094A5 (https=
JP2023542541A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/052044 external-priority patent/WO2022067094A1/en
Publication of JP2023542541A publication Critical patent/JP2023542541A/ja
Publication of JPWO2022067094A5 publication Critical patent/JPWO2022067094A5/ja
Publication of JP2023542541A5 publication Critical patent/JP2023542541A5/ja
Pending legal-status Critical Current

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JP2023518858A 2020-09-25 2021-09-24 Mas関連gタンパク質受容体x2のモジュレーター、並びに関連製品及び方法 Pending JP2023542541A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063083638P 2020-09-25 2020-09-25
US63/083,638 2020-09-25
US202163145407P 2021-02-03 2021-02-03
US63/145,407 2021-02-03
US202163211987P 2021-06-17 2021-06-17
US63/211,987 2021-06-17
PCT/US2021/052044 WO2022067094A1 (en) 2020-09-25 2021-09-24 Modulators of mas-related g-protein receptor x2 and related products and methods

Publications (3)

Publication Number Publication Date
JP2023542541A JP2023542541A (ja) 2023-10-10
JPWO2022067094A5 JPWO2022067094A5 (https=) 2024-10-02
JP2023542541A5 true JP2023542541A5 (https=) 2024-10-02

Family

ID=78302949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023518858A Pending JP2023542541A (ja) 2020-09-25 2021-09-24 Mas関連gタンパク質受容体x2のモジュレーター、並びに関連製品及び方法

Country Status (11)

Country Link
US (2) US11919864B2 (https=)
EP (1) EP4217345A1 (https=)
JP (1) JP2023542541A (https=)
KR (1) KR20230097015A (https=)
CN (1) CN116406357A (https=)
AU (1) AU2021347360A1 (https=)
CA (1) CA3193207A1 (https=)
IL (1) IL301575A (https=)
MX (1) MX2023003476A (https=)
WO (1) WO2022067094A1 (https=)
ZA (1) ZA202304729B (https=)

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Publication number Priority date Publication date Assignee Title
JP2023542541A (ja) * 2020-09-25 2023-10-10 エサイエント ファーマシューティカルズ,インコーポレイティド Mas関連gタンパク質受容体x2のモジュレーター、並びに関連製品及び方法
EP4232042A1 (en) * 2020-10-21 2023-08-30 Escient Pharmaceuticals, Inc. Modulators of mas-related g-protein receptor x2 and related products and their use
CA3245969A1 (en) 2022-03-30 2023-10-05 Escient Pharmaceuticals, Inc. QUINOLINE DERIVATIVES AS MRGPRX2 RECEIVER MODULATORS AND RELATED PRODUCTS
CN115850250B (zh) * 2022-10-25 2025-12-23 南京师范大学 一种可控可视化的一氧化碳释放剂及其制备方法和应用
CN121532382A (zh) * 2023-07-13 2026-02-13 北京普祺医药科技股份有限公司 Mas相关g蛋白受体x2的拮抗剂及其用途
US20250084063A1 (en) 2023-08-18 2025-03-13 Incyte Corporation Bicyclic heterocycles as mrgprx2 antagonists
CN119504738A (zh) * 2023-08-25 2025-02-25 武汉人福创新药物研发中心有限公司 作为mrgprx2拮抗剂的化合物及其制备方法和应用
WO2025119372A2 (zh) * 2023-12-08 2025-06-12 武汉人福创新药物研发中心有限公司 Mrgprx2拮抗剂及用途
WO2025153014A1 (zh) * 2024-01-17 2025-07-24 武汉人福创新药物研发中心有限公司 Mas相关g蛋白受体x2拮抗剂及用途
US20250243208A1 (en) 2024-01-25 2025-07-31 Incyte Corporation Bicyclic heterocycles as mrgprx2 antagonists
WO2025222040A1 (en) 2024-04-19 2025-10-23 Escient Pharmaceuticals, Inc. Mrgprx2 modulators for use in treating mrgprx2 dependent conditions in subjects with low ige
WO2025223036A1 (zh) * 2024-04-23 2025-10-30 凯复(苏州)生物医药有限公司 Mrgprx2拮抗剂、包含其的药物组合物及其用途
WO2025264860A2 (en) 2024-06-18 2025-12-26 Yale University Methods of treating post-covid airway disease
WO2026009854A1 (ja) * 2024-07-01 2026-01-08 日本たばこ産業株式会社 ピリダジノン化合物及びその医薬用途
WO2026037254A1 (zh) * 2024-08-10 2026-02-19 杭州英创医药科技有限公司 作为mrgprx2拮抗剂的化合物

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
KR20030085005A (ko) * 2001-03-19 2003-11-01 니뽄 신야쿠 가부시키가이샤 진양제
KR100955015B1 (ko) * 2001-08-15 2010-04-28 이코스 코포레이션 2h-프탈라진-1-온 및 이것의 사용 방법
US7320989B2 (en) * 2003-02-28 2008-01-22 Encysive Pharmaceuticals, Inc. Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
EP1603884A4 (en) * 2003-02-28 2008-05-28 Encysive Pharmaceuticals Inc PYRIDINE, PYRIMIDINE, QUINOLINE, QUINAZOLINE AND NAPHTHALENE UROTENSIN II RECEPTOR ANTAGONISTS
JP2007517868A (ja) * 2004-01-07 2007-07-05 アストラゼネカ アクチボラグ 治療薬i
JP2006124387A (ja) * 2004-09-30 2006-05-18 Taisho Pharmaceut Co Ltd 新規なキノリン、テトラヒドロキナゾリン、及びピリミジン誘導体と、これらを使用することに関連した治療方法
CN102625799A (zh) * 2009-06-25 2012-08-01 安姆根有限公司 杂环化合物及其用途
CA2853833A1 (en) * 2011-11-08 2013-05-16 Arena Pharmaceuticals, Inc. Modulators of the g protein-coupled mas receptor and the treatment of disorders related thereto
DK2950649T3 (da) * 2013-02-01 2020-05-04 Wellstat Therapeutics Corp Aminforbindelser med antiinflammations-, antisvampe-, antiparasit- og anticanceraktivitet
JP2023542541A (ja) * 2020-09-25 2023-10-10 エサイエント ファーマシューティカルズ,インコーポレイティド Mas関連gタンパク質受容体x2のモジュレーター、並びに関連製品及び方法

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