JP2021504314A5 - - Google Patents
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- Publication number
- JP2021504314A5 JP2021504314A5 JP2020527906A JP2020527906A JP2021504314A5 JP 2021504314 A5 JP2021504314 A5 JP 2021504314A5 JP 2020527906 A JP2020527906 A JP 2020527906A JP 2020527906 A JP2020527906 A JP 2020527906A JP 2021504314 A5 JP2021504314 A5 JP 2021504314A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- kat
- compound according
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*C1CCOCC1 Chemical compound C*C1CCOCC1 0.000 description 12
- XDTMQSROBMDMFD-UHFFFAOYSA-N C1CCCCC1 Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- AIUUAKHKOQFCKF-UHFFFAOYSA-N CCC1COCC1 Chemical compound CCC1COCC1 AIUUAKHKOQFCKF-UHFFFAOYSA-N 0.000 description 1
- ATCIGAHWUUTLKA-UHFFFAOYSA-N CCCS1(C)C(C)NCC1 Chemical compound CCCS1(C)C(C)NCC1 ATCIGAHWUUTLKA-UHFFFAOYSA-N 0.000 description 1
- XLTFIQXBBLAFOT-UHFFFAOYSA-N CCC[N]1(C)C=C(CCCC(C)C)OCC1 Chemical compound CCC[N]1(C)C=C(CCCC(C)C)OCC1 XLTFIQXBBLAFOT-UHFFFAOYSA-N 0.000 description 1
- VJUXYFQNFGMPSV-UHFFFAOYSA-N CSC1=CNC=CC1 Chemical compound CSC1=CNC=CC1 VJUXYFQNFGMPSV-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762592215P | 2017-11-29 | 2017-11-29 | |
| US62/592,215 | 2017-11-29 | ||
| PCT/US2018/063110 WO2019108824A1 (en) | 2017-11-29 | 2018-11-29 | Myst family histone acetyltransferase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021504314A JP2021504314A (ja) | 2021-02-15 |
| JP2021504314A5 true JP2021504314A5 (https=) | 2022-01-06 |
Family
ID=66665802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020527906A Pending JP2021504314A (ja) | 2017-11-29 | 2018-11-29 | Ｍｙｓｔファミリーヒストンアセチルトランスフェラーゼ阻害剤 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11685732B2 (https=) |
| EP (1) | EP3716964A4 (https=) |
| JP (1) | JP2021504314A (https=) |
| KR (1) | KR20200103005A (https=) |
| CN (1) | CN111565717A (https=) |
| AU (1) | AU2018375724A1 (https=) |
| BR (1) | BR112020010628A2 (https=) |
| CA (1) | CA3083616A1 (https=) |
| CL (1) | CL2020001447A1 (https=) |
| CO (1) | CO2020007895A2 (https=) |
| EA (1) | EA202091337A1 (https=) |
| IL (1) | IL274685A (https=) |
| MA (1) | MA51226A (https=) |
| MX (1) | MX2020007131A (https=) |
| SG (1) | SG11202004390VA (https=) |
| WO (1) | WO2019108824A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3137472A1 (en) | 2019-04-25 | 2020-10-29 | Bayer Aktiengesellschaft | Acyl sulfonamides for treating cancer |
| TWI879949B (zh) | 2020-04-27 | 2025-04-11 | 南韓商奧土擇破利悟股份有限公司 | 用於ｕｂｒ盒結構域配體之化合物、組成物以及醫藥組成物 |
| CN112138162B (zh) * | 2020-09-29 | 2021-12-28 | 中国科学院动物研究所 | 降低kat7含量或活性的物质在预防衰老和治疗肝纤维化中的应用 |
| US20240279207A1 (en) * | 2020-10-16 | 2024-08-22 | The Broad Institute, Inc. | Substituted acyl sulfonamides for treating cancer |
| WO2022081842A1 (en) * | 2020-10-16 | 2022-04-21 | The Broad Institute, Inc. | Substituted acyl sulfonamides for treating cancer |
| US20250145637A1 (en) | 2021-08-10 | 2025-05-08 | Jiangsu Hengrui Pharmaceuticals Co. Ltd. | Sulfonamide derivative, preparation method therefor and medical use thereof |
| CN118556053A (zh) | 2021-11-16 | 2024-08-27 | 英矽智能科技知识产权有限公司 | 赖氨酸乙酰基转移酶6a(kat6a)抑制剂及其用途 |
| KR20250143814A (ko) | 2023-02-10 | 2025-10-02 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 설폰아미드 유도체 결정 형태 및 이의 제조 방법 |
| WO2024189598A2 (en) * | 2023-03-16 | 2024-09-19 | Olema Pharmaceuticals, Inc. | Acylsulfonamide kat6a inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4735959A (en) | 1981-01-10 | 1988-04-05 | Dr. Karl Thomae Gmbh | Carboxylic acid amides and pharmaceutical compositions containing them |
| JP2002512633A (ja) * | 1997-06-26 | 2002-04-23 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
| GB201510019D0 (en) * | 2015-06-09 | 2015-07-22 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| EP3548480A1 (en) * | 2016-11-29 | 2019-10-09 | Epizyme, Inc. | Compounds containing a sulfonic group as kat inhibitors |
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2018
- 2018-11-29 MX MX2020007131A patent/MX2020007131A/es unknown
- 2018-11-29 KR KR1020207018039A patent/KR20200103005A/ko not_active Ceased
- 2018-11-29 SG SG11202004390VA patent/SG11202004390VA/en unknown
- 2018-11-29 CA CA3083616A patent/CA3083616A1/en active Pending
- 2018-11-29 AU AU2018375724A patent/AU2018375724A1/en not_active Abandoned
- 2018-11-29 EA EA202091337A patent/EA202091337A1/ru unknown
- 2018-11-29 CN CN201880083981.7A patent/CN111565717A/zh active Pending
- 2018-11-29 WO PCT/US2018/063110 patent/WO2019108824A1/en not_active Ceased
- 2018-11-29 EP EP18883537.5A patent/EP3716964A4/en not_active Withdrawn
- 2018-11-29 JP JP2020527906A patent/JP2021504314A/ja active Pending
- 2018-11-29 BR BR112020010628-3A patent/BR112020010628A2/pt not_active IP Right Cessation
- 2018-11-29 US US16/766,890 patent/US11685732B2/en active Active
- 2018-11-29 MA MA051226A patent/MA51226A/fr unknown
-
2020
- 2020-05-14 IL IL274685A patent/IL274685A/en unknown
- 2020-05-29 CL CL2020001447A patent/CL2020001447A1/es unknown
- 2020-06-26 CO CONC2020/0007895A patent/CO2020007895A2/es unknown
-
2023
- 2023-02-16 US US18/170,319 patent/US20230357208A1/en not_active Abandoned