JP2023526248A5 - - Google Patents

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Publication number
JP2023526248A5
JP2023526248A5 JP2022568794A JP2022568794A JP2023526248A5 JP 2023526248 A5 JP2023526248 A5 JP 2023526248A5 JP 2022568794 A JP2022568794 A JP 2022568794A JP 2022568794 A JP2022568794 A JP 2022568794A JP 2023526248 A5 JP2023526248 A5 JP 2023526248A5
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JP
Japan
Prior art keywords
alkyl
optionally substituted
compound
substituents independently
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2022568794A
Other languages
English (en)
Japanese (ja)
Other versions
JP7606537B2 (ja
JP2023526248A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/031979 external-priority patent/WO2021231565A1/en
Publication of JP2023526248A publication Critical patent/JP2023526248A/ja
Publication of JP2023526248A5 publication Critical patent/JP2023526248A5/ja
Priority to JP2024218934A priority Critical patent/JP7715911B2/ja
Application granted granted Critical
Publication of JP7606537B2 publication Critical patent/JP7606537B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022568794A 2020-05-13 2021-05-12 神経筋疾患の処置のためのピリダジノン化合物 Active JP7606537B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024218934A JP7715911B2 (ja) 2020-05-13 2024-12-13 神経筋疾患の処置のためのピリダジノン化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063024439P 2020-05-13 2020-05-13
US63/024,439 2020-05-13
PCT/US2021/031979 WO2021231565A1 (en) 2020-05-13 2021-05-12 Pyridazinone compounds for the treatment of neuromuscular diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024218934A Division JP7715911B2 (ja) 2020-05-13 2024-12-13 神経筋疾患の処置のためのピリダジノン化合物

Publications (3)

Publication Number Publication Date
JP2023526248A JP2023526248A (ja) 2023-06-21
JP2023526248A5 true JP2023526248A5 (https=) 2024-05-22
JP7606537B2 JP7606537B2 (ja) 2024-12-25

Family

ID=76284178

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022568794A Active JP7606537B2 (ja) 2020-05-13 2021-05-12 神経筋疾患の処置のためのピリダジノン化合物
JP2024218934A Active JP7715911B2 (ja) 2020-05-13 2024-12-13 神経筋疾患の処置のためのピリダジノン化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024218934A Active JP7715911B2 (ja) 2020-05-13 2024-12-13 神経筋疾患の処置のためのピリダジノン化合物

Country Status (4)

Country Link
US (1) US20230159513A1 (https=)
EP (2) EP4149620B1 (https=)
JP (2) JP7606537B2 (https=)
WO (1) WO2021231565A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2958954T3 (es) 2018-11-06 2024-02-16 Edgewise Therapeutics Inc Compuestos de piridazinona y usos de los mismos
WO2020097258A1 (en) 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP3877052B1 (en) 2018-11-06 2023-08-16 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP4433473A1 (en) * 2021-11-17 2024-09-25 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP4509505A4 (en) * 2022-04-15 2026-04-15 Wuhan Humanwell Innovative Drug Res And Development Center Limited Company KIF18A INHIBITOR AND ITS USAGE
EP4688756A1 (en) 2023-03-27 2026-02-11 Edgewise Therapeutics, Inc. Quinazoline dione compounds and uses thereof
WO2024206339A1 (en) 2023-03-27 2024-10-03 Edgewise Therapeutics, Inc. Quinolinone amide compounds and uses thereof
WO2025207622A1 (en) * 2024-03-26 2025-10-02 Edgewise Therapeutics, Inc. Quinolinone, benzoxazinone, and quinoline compounds and uses thereof
WO2025207677A1 (en) * 2024-03-26 2025-10-02 Edgewise Therapeutics, Inc. Quinazolinone compounds and uses thereof
WO2025207665A1 (en) * 2024-03-26 2025-10-02 Edgewise Therapeutics, Inc. Quinolinone compounds and uses thereof
WO2025207679A1 (en) * 2024-03-26 2025-10-02 Edgewise Therapeutics, Inc. Quinazoline dione compounds and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376667A (en) * 1992-12-31 1994-12-27 Entropin, Inc. Derivatives of benzoylecgonine, ecgonine and their multiple pharmacological properties
ES2293638T3 (es) 1994-03-25 2008-03-16 Isotechnika, Inc. Mejora de la eficacia de farmacos por deuteracion.
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
AR081331A1 (es) * 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
US8759380B2 (en) * 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
WO2018081378A1 (en) * 2016-10-26 2018-05-03 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for modulating cftr
CN110573161A (zh) 2017-03-28 2019-12-13 勃林格殷格翰国际有限公司 用于治疗肌营养不良的方法的尼达尼布
US11065243B2 (en) * 2017-10-27 2021-07-20 Sonic Master Limited Inhibitors of DUX4 induction for regulation of muscle function
ES2958954T3 (es) * 2018-11-06 2024-02-16 Edgewise Therapeutics Inc Compuestos de piridazinona y usos de los mismos
WO2020097258A1 (en) * 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP3877052B1 (en) * 2018-11-06 2023-08-16 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP4433473A1 (en) * 2021-11-17 2024-09-25 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof

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