JP2015523339A5 - - Google Patents

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Publication number
JP2015523339A5
JP2015523339A5 JP2015514446A JP2015514446A JP2015523339A5 JP 2015523339 A5 JP2015523339 A5 JP 2015523339A5 JP 2015514446 A JP2015514446 A JP 2015514446A JP 2015514446 A JP2015514446 A JP 2015514446A JP 2015523339 A5 JP2015523339 A5 JP 2015523339A5
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Japan
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cycloalkyl
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JP2015514446A
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Japanese (ja)
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JP6163695B2 (ja
JP2015523339A (ja
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Priority claimed from PCT/EP2013/060844 external-priority patent/WO2013178575A1/en
Publication of JP2015523339A publication Critical patent/JP2015523339A/ja
Publication of JP2015523339A5 publication Critical patent/JP2015523339A5/ja
Application granted granted Critical
Publication of JP6163695B2 publication Critical patent/JP6163695B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015514446A 2012-05-30 2013-05-27 新しいインダニルオキシフェニルシクロプロパンカルボン酸 Expired - Fee Related JP6163695B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12170057.9 2012-05-30
EP12170057 2012-05-30
PCT/EP2013/060844 WO2013178575A1 (en) 2012-05-30 2013-05-27 New indanyloxyphenylcyclopropanecarb oxylic acids

Publications (3)

Publication Number Publication Date
JP2015523339A JP2015523339A (ja) 2015-08-13
JP2015523339A5 true JP2015523339A5 (https=) 2016-07-21
JP6163695B2 JP6163695B2 (ja) 2017-07-19

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ID=48536855

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015514446A Expired - Fee Related JP6163695B2 (ja) 2012-05-30 2013-05-27 新しいインダニルオキシフェニルシクロプロパンカルボン酸

Country Status (4)

Country Link
US (1) US8633182B2 (https=)
EP (1) EP2855419B1 (https=)
JP (1) JP6163695B2 (https=)
WO (1) WO2013178575A1 (https=)

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WO2016019587A1 (en) 2014-08-08 2016-02-11 Merck Sharp & Dohme Corp. [7, 6]-fused bicyclic antidiabetic compounds
KR102431436B1 (ko) 2014-08-29 2022-08-10 테스 파마 에스.알.엘. α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
EP3331860B1 (en) * 2015-08-07 2019-07-17 Boehringer Ingelheim International GmbH Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
CN107216317B (zh) * 2016-03-21 2020-04-07 上海医药工业研究院 一种阿法替尼中间体的制备方法
CN110088089B (zh) 2016-10-25 2023-08-29 勃林格殷格翰国际有限公司 苄基氨基吡啶基环丙烷甲酸、药物组合物及其用途
US10125101B2 (en) 2016-11-28 2018-11-13 Boehringer Ingelheim International Gmbh Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
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JP7050792B2 (ja) 2017-01-26 2022-04-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンジルオキシピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用
CN110214135B (zh) * 2017-01-26 2023-02-21 勃林格殷格翰国际有限公司 茚满基氨基吡嗪基环丙烷羧酸、药物组合物及其用途
EP3573959B1 (en) 2017-01-26 2021-07-28 Boehringer Ingelheim International GmbH Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
CN110177773B (zh) * 2017-01-26 2023-08-25 勃林格殷格翰国际有限公司 苄基氨基吡啶基环丙烷羧酸、其药物组合物及其用途
US10913720B2 (en) 2017-01-26 2021-02-09 Boehringer Ingelheim International Gmbh Benzyloxypyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
US10550127B1 (en) 2017-02-08 2020-02-04 Boehringer Ingelheim International Gmbh Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes
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TWI707849B (zh) 2018-02-13 2020-10-21 美商基利科學股份有限公司 Pd‐1/pd‐l1抑制劑
US12083118B2 (en) 2018-03-29 2024-09-10 Arbutus Biopharma Corporation Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same
KR102591947B1 (ko) 2018-04-19 2023-10-25 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
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