JP2016534134A5 - - Google Patents
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- JP2016534134A5 JP2016534134A5 JP2016540436A JP2016540436A JP2016534134A5 JP 2016534134 A5 JP2016534134 A5 JP 2016534134A5 JP 2016540436 A JP2016540436 A JP 2016540436A JP 2016540436 A JP2016540436 A JP 2016540436A JP 2016534134 A5 JP2016534134 A5 JP 2016534134A5
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- Japan
- Prior art keywords
- hydroxy
- alkyl
- cyano
- compound
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- Prior art date
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- 0 *#Cc(c([C@]1N=O)c2CC1(F)F)ccc2Oc1cc(F)cc(F)c1 Chemical compound *#Cc(c([C@]1N=O)c2CC1(F)F)ccc2Oc1cc(F)cc(F)c1 0.000 description 6
- ZGVWZAJMWJIHNT-HNNXBMFYSA-N CS(c(c([C@@H]1O)c2CC1(F)F)ccc2Oc1cc(F)cc(F)c1)(=O)=O Chemical compound CS(c(c([C@@H]1O)c2CC1(F)F)ccc2Oc1cc(F)cc(F)c1)(=O)=O ZGVWZAJMWJIHNT-HNNXBMFYSA-N 0.000 description 1
- YSQBDUMLHQLQBH-HPGBDJQBSA-N C[S@](c(cc1)c([C@@H](C(C2)(F)F)O)c2c1Oc1cc(C#N)cc(F)c1)(=NC#N)=O Chemical compound C[S@](c(cc1)c([C@@H](C(C2)(F)F)O)c2c1Oc1cc(C#N)cc(F)c1)(=NC#N)=O YSQBDUMLHQLQBH-HPGBDJQBSA-N 0.000 description 1
- KXKBSLFAMIIKMT-UHFFFAOYSA-N OC(C(Cc1c(cc2)Oc(cc3)c(cn[nH]4)c4c3F)(F)F)c1c2S(C(F)(F)F)(=O)=O Chemical compound OC(C(Cc1c(cc2)Oc(cc3)c(cn[nH]4)c4c3F)(F)F)c1c2S(C(F)(F)F)(=O)=O KXKBSLFAMIIKMT-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361875674P | 2013-09-09 | 2013-09-09 | |
| US61/875,674 | 2013-09-09 | ||
| US201461978421P | 2014-04-11 | 2014-04-11 | |
| US61/978,421 | 2014-04-11 | ||
| PCT/US2014/054375 WO2015035223A1 (en) | 2013-09-09 | 2014-09-05 | Aryl ethers and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019018100A Division JP6746733B2 (ja) | 2013-09-09 | 2019-02-04 | アリールエーテルおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016534134A JP2016534134A (ja) | 2016-11-04 |
| JP2016534134A5 true JP2016534134A5 (https=) | 2017-10-12 |
| JP6486940B2 JP6486940B2 (ja) | 2019-03-20 |
Family
ID=52628976
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540436A Active JP6486940B2 (ja) | 2013-09-09 | 2014-09-05 | アリールエーテルおよびその使用 |
| JP2019018100A Active JP6746733B2 (ja) | 2013-09-09 | 2019-02-04 | アリールエーテルおよびその使用 |
| JP2019052947A Active JP6918039B2 (ja) | 2013-09-09 | 2019-03-20 | アリールエーテルおよびその使用 |
| JP2019052946A Pending JP2019089855A (ja) | 2013-09-09 | 2019-03-20 | アリールエーテルおよびその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019018100A Active JP6746733B2 (ja) | 2013-09-09 | 2019-02-04 | アリールエーテルおよびその使用 |
| JP2019052947A Active JP6918039B2 (ja) | 2013-09-09 | 2019-03-20 | アリールエーテルおよびその使用 |
| JP2019052946A Pending JP2019089855A (ja) | 2013-09-09 | 2019-03-20 | アリールエーテルおよびその使用 |
Country Status (33)
| Country | Link |
|---|---|
| US (7) | US9908845B2 (https=) |
| EP (4) | EP3043784B9 (https=) |
| JP (4) | JP6486940B2 (https=) |
| KR (1) | KR102153772B1 (https=) |
| CN (2) | CN110372550B (https=) |
| AU (1) | AU2014318025B2 (https=) |
| BR (1) | BR112016005262B1 (https=) |
| CA (1) | CA2919397C (https=) |
| CU (1) | CU24385B1 (https=) |
| CY (3) | CY1122144T1 (https=) |
| DK (1) | DK3043784T3 (https=) |
| EA (1) | EA032124B1 (https=) |
| ES (3) | ES2739433T3 (https=) |
| FI (1) | FIC20253001I1 (https=) |
| FR (1) | FR25C1018I2 (https=) |
| HR (2) | HRP20201701T8 (https=) |
| HU (3) | HUE045462T2 (https=) |
| IL (1) | IL243888B (https=) |
| LT (3) | LT3417851T (https=) |
| MX (1) | MX2016002974A (https=) |
| MY (1) | MY199426A (https=) |
| NL (1) | NL301327I2 (https=) |
| NO (1) | NO2025022I1 (https=) |
| PE (1) | PE20160434A1 (https=) |
| PL (2) | PL3417851T3 (https=) |
| PT (2) | PT3043784T (https=) |
| RS (2) | RS58960B1 (https=) |
| SG (1) | SG11201601616SA (https=) |
| SI (2) | SI3043784T1 (https=) |
| SM (1) | SMT201900479T1 (https=) |
| TW (2) | TW201936572A (https=) |
| UY (1) | UY35731A (https=) |
| WO (1) | WO2015035223A1 (https=) |
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| AU2014318979B2 (en) | 2013-09-10 | 2019-03-28 | Chromocell Corporation | Sodium channel modulators for the treatment of pain and diabetes |
| US9884843B2 (en) | 2013-12-16 | 2018-02-06 | Peloton Therapeutics, Inc. | Cyclic sulfone and sulfoximine analogs and uses thereof |
| WO2016057242A1 (en) * | 2014-10-10 | 2016-04-14 | The Board Of Regents Of The University Of Texas System | HIF-2α INHIBITORS FOR TREATING IRON OVERLOAD DISORDERS |
| US10512626B2 (en) * | 2015-03-11 | 2019-12-24 | Peloton Therapeautics, Inc. | Compositions for use in treating glioblastoma |
| WO2016144826A1 (en) * | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
| WO2016145236A1 (en) * | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Hif-2-alpha inhibitor polymorphs |
| WO2016144825A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
| US10278942B2 (en) | 2015-03-11 | 2019-05-07 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
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| US9796697B2 (en) | 2015-06-12 | 2017-10-24 | Peloton Therapeutics, Inc. | Tricyclic inhibitors of HIF-2-alpha and uses thereof |
| CN105566406A (zh) * | 2015-12-30 | 2016-05-11 | 江西胜富化工有限公司 | 一种氟代脱氧呋喃核糖的制备方法 |
| WO2018031680A1 (en) * | 2016-08-10 | 2018-02-15 | Fronthera U.S. Pharmaceuticals Llc | Novel compounds, uses and methods for their preparation |
| CN110167939B (zh) * | 2017-01-11 | 2021-12-31 | 江苏豪森药业集团有限公司 | 吡咯并[2,3-c]吡啶类衍生物、其制备方法及其在医药上的应用 |
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| UA129778C2 (uk) | 2019-10-28 | 2025-07-30 | Мерк Шарп Енд Доум Елелсі | Низькомолекулярні інгібітори g12c-мутантного kras |
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| TW202136248A (zh) | 2019-11-25 | 2021-10-01 | 德商拜耳廠股份有限公司 | 作為殺蟲劑之新穎雜芳基-三唑化合物 |
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