JP2021514001A5 - - Google Patents
Info
- Publication number
- JP2021514001A5 JP2021514001A5 JP2020544510A JP2020544510A JP2021514001A5 JP 2021514001 A5 JP2021514001 A5 JP 2021514001A5 JP 2020544510 A JP2020544510 A JP 2020544510A JP 2020544510 A JP2020544510 A JP 2020544510A JP 2021514001 A5 JP2021514001 A5 JP 2021514001A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkylene
- salt according
- salt
- alkyl
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024009496A JP2024056735A (ja) | 2018-02-23 | 2024-01-25 | Ｅｇｆｒ二量体撹乱剤およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862634452P | 2018-02-23 | 2018-02-23 | |
| US62/634,452 | 2018-02-23 | ||
| PCT/US2019/019391 WO2019165358A1 (en) | 2018-02-23 | 2019-02-25 | Egfr dimer disruptors and use of the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024009496A Division JP2024056735A (ja) | 2018-02-23 | 2024-01-25 | Ｅｇｆｒ二量体撹乱剤およびその使用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514001A JP2021514001A (ja) | 2021-06-03 |
| JPWO2019165358A5 JPWO2019165358A5 (https=) | 2022-03-03 |
| JP2021514001A5 true JP2021514001A5 (https=) | 2022-03-03 |
| JP7497046B2 JP7497046B2 (ja) | 2024-06-10 |
Family
ID=67688515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544510A Active JP7497046B2 (ja) | 2018-02-23 | 2019-02-25 | Ｅｇｆｒ二量体撹乱剤およびその使用 |
| JP2024009496A Pending JP2024056735A (ja) | 2018-02-23 | 2024-01-25 | Ｅｇｆｒ二量体撹乱剤およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024009496A Pending JP2024056735A (ja) | 2018-02-23 | 2024-01-25 | Ｅｇｆｒ二量体撹乱剤およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11358965B2 (https=) |
| EP (1) | EP3755323A4 (https=) |
| JP (2) | JP7497046B2 (https=) |
| KR (1) | KR102748047B1 (https=) |
| CN (1) | CN111886009A (https=) |
| AU (1) | AU2019223168B2 (https=) |
| BR (1) | BR112020017184A2 (https=) |
| CA (1) | CA3091834A1 (https=) |
| EA (1) | EA202092000A1 (https=) |
| MX (1) | MX2020008767A (https=) |
| WO (1) | WO2019165358A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3091834A1 (en) * | 2018-02-23 | 2019-08-29 | The Regents Of The University Of Michigan | Egfr dimer disruptors and use of the same |
| CN114286676A (zh) * | 2019-08-22 | 2022-04-05 | 密歇根大学董事会 | 治疗kras相关癌症的方法 |
| CA3172812A1 (en) * | 2020-03-05 | 2021-09-10 | The Regents Of The University Of Michigan | Inhibitors of egfr, kras, braf, and other targets and use of the same |
| MX2022010977A (es) * | 2020-03-05 | 2022-12-02 | Univ Michigan Regents | Inhibidores de egfr, kras, braf y otros objetivos y uso de los mismos. |
| IL301532A (en) | 2020-09-23 | 2023-05-01 | Scorpion Therapeutics Inc | History Pyrrolo[2,3-C]pyridin-4-one is useful in cancer treatment |
| WO2022072632A1 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Bicyclic compounds for use in the treatment cancer |
| WO2022072645A2 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| TW202229282A (zh) | 2020-09-30 | 2022-08-01 | 美商史考皮恩治療有限公司 | 治療癌症之方法 |
| BR112023006531A2 (pt) | 2020-10-09 | 2023-10-03 | Scorpion Therapeutics Inc | Inibidores heterocílicos de egfr e/ou her2, para uso no tratamento de câncer |
| EP4225304B1 (en) * | 2020-10-12 | 2025-12-17 | The Regents of The University of Michigan | Synthesis of egfr modulators |
| WO2022077154A1 (en) * | 2020-10-12 | 2022-04-21 | The Regents Of The University Of Michigan | Synthesis of egfr modulators |
| WO2022094271A1 (en) | 2020-10-30 | 2022-05-05 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| WO2022098992A1 (en) | 2020-11-05 | 2022-05-12 | Scorpion Therapeutics, Inc. | Use of macrocyclic compounds in methods of treating cancer |
| WO2022197913A1 (en) | 2021-03-18 | 2022-09-22 | Scorpion Therapeutics, Inc. | Bicyclic derivatives which can be used to treat cancer |
| EP4323356A1 (en) | 2021-04-13 | 2024-02-21 | Nuvalent, Inc. | Amino-substituted heterocycles for treating cancers with egfr mutations |
| WO2023173083A1 (en) | 2022-03-11 | 2023-09-14 | Scorpion Therapeutics, Inc. | Tetrahydroindole derivatives as egfr and/or her2 inhibtors useful for the treatment of cancer |
| CN121909190A (zh) | 2023-06-08 | 2026-04-21 | 安塔列斯疗法股份有限公司 | 1,5-二氢-4H-吡咯并[3,2-c]吡啶-4-酮用于癌症治疗 |
| CN121712773A (zh) | 2023-06-08 | 2026-03-20 | 安塔列斯疗法股份有限公司 | 1,5-二氢-4h-吡咯并[3,2-c]吡啶-4-酮用于癌症治疗 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3547977A (en) | 1967-10-27 | 1970-12-15 | Velsicol Chemical Corp | Novel carbanilates |
| US5466468A (en) | 1990-04-03 | 1995-11-14 | Ciba-Geigy Corporation | Parenterally administrable liposome formulation comprising synthetic lipids |
| CA2709784A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2012087943A2 (en) | 2010-12-20 | 2012-06-28 | The Regents Of The University Of Michigan | Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction |
| WO2014176475A2 (en) * | 2013-04-26 | 2014-10-30 | The Regents Of The University Of Michigan | Egfr inhibitors and uses thereof |
| US9499551B2 (en) * | 2014-01-24 | 2016-11-22 | Confluence Life Sciences, Inc. | Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases |
| CN113563332B (zh) * | 2014-12-23 | 2024-12-17 | 达纳－法伯癌症研究所公司 | 作为egfr抑制剂的新的嘧啶和治疗病症的方法 |
| CA3091834A1 (en) | 2018-02-23 | 2019-08-29 | The Regents Of The University Of Michigan | Egfr dimer disruptors and use of the same |
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2019
- 2019-02-25 CA CA3091834A patent/CA3091834A1/en active Pending
- 2019-02-25 EP EP19757355.3A patent/EP3755323A4/en active Pending
- 2019-02-25 MX MX2020008767A patent/MX2020008767A/es unknown
- 2019-02-25 WO PCT/US2019/019391 patent/WO2019165358A1/en not_active Ceased
- 2019-02-25 US US16/970,655 patent/US11358965B2/en active Active
- 2019-02-25 KR KR1020207027147A patent/KR102748047B1/ko active Active
- 2019-02-25 EA EA202092000A patent/EA202092000A1/ru unknown
- 2019-02-25 CN CN201980020234.3A patent/CN111886009A/zh active Pending
- 2019-02-25 JP JP2020544510A patent/JP7497046B2/ja active Active
- 2019-02-25 AU AU2019223168A patent/AU2019223168B2/en active Active
- 2019-02-25 BR BR112020017184-0A patent/BR112020017184A2/pt unknown
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2022
- 2022-05-09 US US17/739,358 patent/US11999731B2/en active Active
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2024
- 2024-01-25 JP JP2024009496A patent/JP2024056735A/ja active Pending