CL2008001709A1 - Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras. - Google Patents

Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.

Info

Publication number
CL2008001709A1
CL2008001709A1 CL2008001709A CL2008001709A CL2008001709A1 CL 2008001709 A1 CL2008001709 A1 CL 2008001709A1 CL 2008001709 A CL2008001709 A CL 2008001709A CL 2008001709 A CL2008001709 A CL 2008001709A CL 2008001709 A1 CL2008001709 A1 CL 2008001709A1
Authority
CL
Chile
Prior art keywords
psoriasis
modulators
pyrimidine
cancer
pharmaceutical composition
Prior art date
Application number
CL2008001709A
Other languages
English (en)
Inventor
James D Rodgers
Argyrios G Arvanitis
Jack Guoen Shi
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US94369507P priority Critical
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CL2008001709A1 publication Critical patent/CL2008001709A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Abstract

Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composición farmacéutica; y uso en el tratamiento de enfermedades, tales como, cáncer, psoriasis, artritis reumatoide, entre otras.
CL2008001709A 2007-06-13 2008-06-10 Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras. CL2008001709A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US94369507P true 2007-06-13 2007-06-13

Publications (1)

Publication Number Publication Date
CL2008001709A1 true CL2008001709A1 (es) 2008-11-03

Family

ID=40029276

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008001709A CL2008001709A1 (es) 2007-06-13 2008-06-10 Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.

Country Status (25)

Country Link
US (3) US7834022B2 (es)
EP (1) EP2173751B1 (es)
JP (1) JP5479331B2 (es)
KR (1) KR20100049008A (es)
CN (1) CN101815717B (es)
AR (1) AR067024A1 (es)
AU (1) AU2008266182B8 (es)
BR (1) BRPI0812563A2 (es)
CA (1) CA2689158C (es)
CL (1) CL2008001709A1 (es)
CO (1) CO6251255A2 (es)
CR (1) CR11149A (es)
EA (1) EA017790B1 (es)
EC (1) ECSP099821A (es)
ES (1) ES2448868T3 (es)
GE (1) GEP20125534B (es)
HK (1) HK1141020A1 (es)
IL (1) IL202429D0 (es)
MX (2) MX339139B (es)
NZ (1) NZ581801A (es)
PT (1) PT2173751E (es)
TW (1) TWI426911B (es)
UA (1) UA99465C2 (es)
WO (1) WO2008157207A2 (es)
ZA (1) ZA200908820B (es)

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GEP20125534B (en) 2012-05-25
US8889697B2 (en) 2014-11-18
AU2008266182B8 (en) 2014-09-18
EA201070012A1 (ru) 2010-06-30
EP2173751A2 (en) 2010-04-14
CA2689158A1 (en) 2008-12-24
IL202429D0 (en) 2010-06-30
CA2689158C (en) 2015-10-06
US20080312258A1 (en) 2008-12-18
CR11149A (es) 2010-02-04
MX339139B (es) 2016-05-13
TW200911264A (en) 2009-03-16
US7834022B2 (en) 2010-11-16
KR20100049008A (ko) 2010-05-11
TWI426911B (zh) 2014-02-21
ECSP099821A (es) 2010-01-29
AU2008266182A8 (en) 2014-09-18
JP5479331B2 (ja) 2014-04-23
ES2448868T3 (es) 2014-03-17
BRPI0812563A2 (pt) 2015-02-10
HK1141020A1 (en) 2014-07-11
AU2008266182A1 (en) 2008-12-24
EA017790B1 (ru) 2013-03-29
JP2010529208A (ja) 2010-08-26
NZ581801A (en) 2012-04-27
AU2008266182B2 (en) 2014-05-08
CN101815717B (zh) 2014-06-25
AR067024A1 (es) 2009-09-30
MX2009013403A (es) 2010-02-24
CO6251255A2 (es) 2011-02-21
PT2173751E (pt) 2014-02-14
EP2173751B1 (en) 2013-11-27
US20170326144A1 (en) 2017-11-16
CN101815717A (zh) 2010-08-25
US20110082159A1 (en) 2011-04-07
US20150164900A1 (en) 2015-06-18
UA99465C2 (xx) 2012-08-27
WO2008157207A2 (en) 2008-12-24
ZA200908820B (en) 2013-05-29
WO2008157207A3 (en) 2009-02-26

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