AU3565999A - Synthesis of azetidine derivatives - Google Patents

Synthesis of azetidine derivatives

Info

Publication number
AU3565999A
AU3565999A AU35659/99A AU3565999A AU3565999A AU 3565999 A AU3565999 A AU 3565999A AU 35659/99 A AU35659/99 A AU 35659/99A AU 3565999 A AU3565999 A AU 3565999A AU 3565999 A AU3565999 A AU 3565999A
Authority
AU
Australia
Prior art keywords
synthesis
azetidine derivatives
azetidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35659/99A
Inventor
Zhengming Chen
Zhi-Min Huang
Hatmuth C. Kolb
Paul Richardson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coelacanth Chemical Corp
Original Assignee
Coelacanth Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coelacanth Chemical Corp filed Critical Coelacanth Chemical Corp
Publication of AU3565999A publication Critical patent/AU3565999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
AU35659/99A 1999-04-16 1999-04-16 Synthesis of azetidine derivatives Abandoned AU3565999A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/008361 WO2000063168A1 (en) 1999-04-16 1999-04-16 Synthesis of azetidine derivatives

Publications (1)

Publication Number Publication Date
AU3565999A true AU3565999A (en) 2000-11-02

Family

ID=22272579

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35659/99A Abandoned AU3565999A (en) 1999-04-16 1999-04-16 Synthesis of azetidine derivatives

Country Status (2)

Country Link
AU (1) AU3565999A (en)
WO (1) WO2000063168A1 (en)

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PL2474545T3 (en) 2005-12-13 2017-04-28 Incyte Holdings Corporation Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
HUE043732T2 (en) 2007-06-13 2019-09-30 Incyte Holdings Corp Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
AU2009223640B2 (en) 2008-03-11 2013-07-04 Incyte Holdings Corporation Azetidine and cyclobutane derivatives as jak inhibitors
US8435977B2 (en) 2009-04-22 2013-05-07 Janssen Pharmaceutica, Nv Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
RS53235B (en) 2009-04-22 2014-08-29 Janssen Pharmaceutica N.V. Azetidinyl diamides as monoacylglycerol lipase inhibitors
AU2010249380B2 (en) 2009-05-22 2015-08-20 Incyte Holdings Corporation N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as Janus kinase inhibitors
CA2761954C (en) 2009-05-22 2018-07-31 Incyte Corporation 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
TW201113285A (en) 2009-09-01 2011-04-16 Incyte Corp Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
AR081315A1 (en) 2010-03-10 2012-08-08 Incyte Corp HETEROCICLIC DERIVATIVES OF PIPERIDIN AND PIRIMIDIN -4-IL-AZETIDINA, A CRYSTALLINE FORM OF THE SALT OF ACETONITRILADIPICO ACID OF A PYRIMIDINIC DERIVATIVE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE OF THE SAME THINGS WITH THE TREATMENT OF INJECTION , T
NZ603686A (en) 2010-05-21 2014-11-28 Incyte Corp Topical formulation for a jak inhibitor
JP2013536852A (en) 2010-09-03 2013-09-26 ヤンセン ファーマシューティカ エヌ．ベー． Di-azetidinyl diamides as monoacylglycerol lipase inhibitors
WO2012044613A1 (en) 2010-09-27 2012-04-05 Janssen Pharmaceutica Nv Oxopiperazine-azetidine amides and oxodiazepine-azetidine amides as monoacylglycerol lipase inhibitors
WO2012054721A1 (en) 2010-10-22 2012-04-26 Janssen Pharmaceutical Nv Amino-pyrrolidine-azetidine diamides as monoacylglycerol lipase inhibitors
US8513423B2 (en) 2010-10-22 2013-08-20 Janssen Pharmaceutica, Nv Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors
JP5917544B2 (en) 2010-11-19 2016-05-18 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Heterocyclic substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
EA026201B1 (en) 2010-11-19 2017-03-31 Инсайт Холдингс Корпорейшн Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
AR086983A1 (en) 2011-06-20 2014-02-05 Incyte Corp DERIVATIVES OF AZETIDINIL FENIL, PIRIDIL OR PIRAZINIL CARBOXAMIDA AS JAK INHIBITORS
TW201313721A (en) 2011-08-18 2013-04-01 Incyte Corp Cyclohexyl azetidine derivatives as JAK inhibitors
UA111854C2 (en) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн METHODS AND INTERMEDIATE COMPOUNDS FOR JAK INHIBITORS
AR091079A1 (en) 2012-05-18 2014-12-30 Incyte Corp DERIVATIVES OF PIRROLOPIRIMIDINA AND PIRROLOPIRIDINA REPLACED WITH PIPERIDINILCICLOBUTILO AS JAK INHIBITORS
PL2919766T3 (en) 2012-11-15 2021-10-04 Incyte Holdings Corporation Sustained-release dosage forms of ruxolitinib
AU2014225938B2 (en) 2013-03-06 2018-07-19 Incyte Holdings Corporation Processes and intermediates for making a JAK inhibitor
MX2016001639A (en) 2013-08-07 2016-10-07 Incyte Corp Sustained release dosage forms for a jak1 inhibitor.
WO2015184305A1 (en) 2014-05-30 2015-12-03 Incyte Corporation TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
WO2018174266A1 (en) 2017-03-24 2018-09-27 湧永製薬株式会社 Novel pyridone carboxylic acid derivative or salt thereof
US10596161B2 (en) 2017-12-08 2020-03-24 Incyte Corporation Low dose combination therapy for treatment of myeloproliferative neoplasms
DK3746429T3 (en) 2018-01-30 2022-05-02 Incyte Corp PROCEDURES FOR THE PREPARATION OF (1- (3-FLUORO-2- (TRIFLUOROMETHYL) ISONICOTINYL) PIPERIDIN-4-ON)
UA127925C2 (en) 2018-03-30 2024-02-14 Інсайт Корпорейшн Treatment of hidradenitis suppurativa using jak inhibitors
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

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US4705853A (en) * 1982-09-30 1987-11-10 A. H. Robins Company, Inc. Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof
FR2560194B1 (en) * 1984-02-27 1987-08-07 Midy Spa 3-AMINOAZETIDINE, ITS SALTS, PROCESS FOR THEIR PREPARATION AND SYNTHESIS INTERMEDIATES
US4960776A (en) * 1987-01-28 1990-10-02 A. H. Robins Company, Inc. 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides
FR2645862B1 (en) * 1989-04-18 1991-07-12 Esteve Labor Dr SUBSTITUTED ISOTHIAZOLO-PYRYDONE AZETIDINYL DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2649100B1 (en) * 1989-06-29 1994-03-04 Laboratorios Dr Esteve Sa NOVEL AZETIDINES, THEIR PREPARATION AND THEIR APPLICATION AS INTERMEDIATES FOR THE PREPARATION OF COMPOUNDS WITH ANTIMICROBIAL ACTIVITY
TW209870B (en) * 1990-01-18 1993-07-21 Pfizer
US5442044A (en) * 1991-01-04 1995-08-15 Pfizer Inc. Orally active renin inhibitors
FR2681865B1 (en) * 1991-10-01 1993-11-19 Bel Laboratoire Roger NOVEL BENZONAPHTYRIDINE-1,8 DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
US5849780A (en) * 1992-01-30 1998-12-15 Sanofi 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present
KR970703324A (en) * 1994-05-18 1997-07-03 쇼오다 오사무 Novel pyrimidine derivatives (NOVEL PYRIMIDINE DERIVATIVE)
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
AU8150198A (en) * 1997-06-18 1999-01-04 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
AU1089599A (en) * 1997-10-15 1999-05-03 Coelacanth Chemical Corporation Synthesis of azetidine derivatives

Also Published As

Publication number Publication date
WO2000063168A1 (en) 2000-10-26

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase