GB0115393D0 - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- GB0115393D0 GB0115393D0 GBGB0115393.1A GB0115393A GB0115393D0 GB 0115393 D0 GB0115393 D0 GB 0115393D0 GB 0115393 A GB0115393 A GB 0115393A GB 0115393 D0 GB0115393 D0 GB 0115393D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (35)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0115393.1A GB0115393D0 (en) | 2001-06-23 | 2001-06-23 | Chemical compounds |
| YU99203A RS51698B (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as Protein Kinase Inhibitors |
| HR20031049A HRP20031049A2 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| MEP-193/08A MEP19308A (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| CZ20033443A CZ20033443A3 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| HU0400300A HUP0400300A3 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| KR1020037016809A KR100875380B1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidine as a Protein Kinase Inhibitor |
| HK05100184.1A HK1068134B (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| AU2002314325A AU2002314325B8 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| PL02374096A PL374096A1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| EP02740895A EP1404676A1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| TR2003/02242T TR200302242T2 (en) | 2001-06-23 | 2002-06-21 | Pyrolopyrimidines as protein kinase inhibitors |
| IL15950602A IL159506A0 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| CNB028119320A CN1294135C (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| APAP/P/2003/002929A AP2003002929A0 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| PCT/GB2002/002835 WO2003000695A1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| UA2004010502A UA76760C2 (en) | 2001-06-23 | 2002-06-21 | Pyrrole pyrimidines as protein kinase inhibitors |
| JP2003507098A JP4344607B2 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| MXPA03011998A MXPA03011998A (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors. |
| EA200400073A EA007415B1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| OA1200300335A OA12632A (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors. |
| SK1588-2003A SK15882003A3 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| BR0210652-3A BR0210652A (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| CA002451932A CA2451932C (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| TNPCT/GB2002/002835A TNSN03144A1 (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| EEP200400003A EE05432B1 (en) | 2001-06-23 | 2002-06-21 | P rrolop rimidines as protein kinase inhibitors |
| NZ529766A NZ529766A (en) | 2001-06-23 | 2002-06-21 | Pyrrolopyrimidines as protein kinase inhibitors |
| CR7193A CR7193A (en) | 2001-06-23 | 2003-12-10 | PIRROLOPIRIMIDINAS AS INHIBITORS OF THE KINASA PROTENINE |
| BG108453A BG108453A (en) | 2001-06-23 | 2003-12-15 | Pyrrolopyrimidines as protein kinase inhibitors |
| MA27444A MA27129A1 (en) | 2001-06-23 | 2003-12-16 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS. |
| NO20035728A NO20035728L (en) | 2001-06-23 | 2003-12-19 | Pyrrolopyrimidines as protein kinase inhibitors |
| CO03111600A CO5540313A2 (en) | 2001-06-23 | 2003-12-22 | PIRROLOPIRIMIDINAS AS INHIBITORS OF PROTEIN QUINASA |
| IL159506A IL159506A (en) | 2001-06-23 | 2003-12-22 | Pyrrolopyrimidines as protein kinase inhibitors |
| US10/744,478 US7259154B2 (en) | 2001-06-23 | 2003-12-23 | Pyrrolopyrimidines |
| EC2003004922A ECSP034922A (en) | 2001-06-23 | 2003-12-23 | PIRROLOPIRIMIDINES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0115393.1A GB0115393D0 (en) | 2001-06-23 | 2001-06-23 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0115393D0 true GB0115393D0 (en) | 2001-08-15 |
Family
ID=9917225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0115393.1A Ceased GB0115393D0 (en) | 2001-06-23 | 2001-06-23 | Chemical compounds |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1404676A1 (en) |
| JP (1) | JP4344607B2 (en) |
| CN (1) | CN1294135C (en) |
| AU (1) | AU2002314325B8 (en) |
| BR (1) | BR0210652A (en) |
| CA (1) | CA2451932C (en) |
| CZ (1) | CZ20033443A3 (en) |
| EA (1) | EA007415B1 (en) |
| EC (1) | ECSP034922A (en) |
| EE (1) | EE05432B1 (en) |
| GB (1) | GB0115393D0 (en) |
| HU (1) | HUP0400300A3 (en) |
| ME (1) | MEP19308A (en) |
| NZ (1) | NZ529766A (en) |
| OA (1) | OA12632A (en) |
| PL (1) | PL374096A1 (en) |
| RS (1) | RS51698B (en) |
| SK (1) | SK15882003A3 (en) |
| TN (1) | TNSN03144A1 (en) |
| TR (1) | TR200302242T2 (en) |
| UA (1) | UA76760C2 (en) |
| WO (1) | WO2003000695A1 (en) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| GB0202679D0 (en) * | 2002-02-05 | 2002-03-20 | Glaxo Group Ltd | Novel compounds |
| IL166241A0 (en) | 2002-07-29 | 2006-01-15 | Rigel Pharmaceuticals Inc | Method of treating or preventing autoimmune diseases with 2,4-pyrimidinedinediamine compounds |
| US8178671B2 (en) | 2003-07-30 | 2012-05-15 | Rigel Pharmaceuticals, Inc. | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds |
| MXPA06005578A (en) | 2003-11-17 | 2006-08-11 | Pfizer Prod Inc | Pyrrolopyrimidine compounds useful in treatment of cancer. |
| BRPI0416909A (en) * | 2003-11-25 | 2007-01-16 | Pfizer Prod Inc | atherosclerosis treatment method |
| US20050250829A1 (en) * | 2004-04-23 | 2005-11-10 | Takeda San Diego, Inc. | Kinase inhibitors |
| WO2006023931A2 (en) | 2004-08-18 | 2006-03-02 | Takeda San Diego, Inc. | Kinase inhibitors |
| FR2876103B1 (en) | 2004-10-01 | 2008-02-22 | Aventis Pharma Sa | NOVEL BIS-AZAINDOL DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE AS INHIBITORS OF KINASES |
| ATE479687T1 (en) | 2004-10-15 | 2010-09-15 | Takeda Pharmaceutical | KINASE INHIBITORS |
| FR2878849B1 (en) | 2004-12-06 | 2008-09-12 | Aventis Pharma Sa | SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING SAME, METHOD OF MANUFACTURE AND USE |
| US7576053B2 (en) | 2005-06-13 | 2009-08-18 | Rigel Pharmaceuticals, Inc. | Methods and compositions for treating degenerative bone disorders |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| DK3184526T3 (en) | 2005-12-13 | 2019-01-14 | Incyte Holdings Corp | PYRROLO [2,3-D] PYRIMIDINE DERIVATIVES AS A JANUS-KINASE INHIBITOR |
| BRPI0719883A2 (en) | 2006-10-09 | 2015-05-05 | Takeda Pharmaceutical | Kinase Inhibitors |
| EP2740731B1 (en) | 2007-06-13 | 2016-03-23 | Incyte Holdings Corporation | Crystalline salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| AP2010005347A0 (en) | 2008-01-11 | 2010-08-31 | Natco Pharma Ltd | Novel pyrazolo [3,4-D] pyrimidine derivatives as anti-cancer agents |
| UY31881A (en) | 2008-06-10 | 2010-01-29 | Abbott Lab | SUBSTITUTED DERIVATIVES OF IMIDAZO [1,5-A] PIRROLO [2,3-E] PIRAZINAS AND IMIDAZO [1,2-A] PIRROLO [2,3-E] PIRAZINAS, ITS SALTS, PRODROGAS, BIOLOGICAL METABOLITES E STEREOISÓMEROS E PHARMACEUTICALLY ACCEPTABLE ISOMERS. |
| WO2010135621A1 (en) | 2009-05-22 | 2010-11-25 | Incyte Corporation | 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors |
| ES2487542T3 (en) | 2009-05-22 | 2014-08-21 | Incyte Corporation | N- (hetero) aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo [2,3-d] pyrimidines and pyrrol-3-yl-pyrrolo [2,3-d] pyrimidines as Janus kinase inhibitors |
| WO2011018894A1 (en) * | 2009-08-10 | 2011-02-17 | Raqualia Pharma Inc. | Pyrrolopyrimidine derivatives as potassium channel modulators |
| WO2011028685A1 (en) | 2009-09-01 | 2011-03-10 | Incyte Corporation | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| US9029359B2 (en) | 2009-09-04 | 2015-05-12 | Biogen Idec Ma, Inc. | Heteroaryl Btk inhibitors |
| CA2991896A1 (en) * | 2009-12-01 | 2011-06-09 | Abbvie Inc. | Novel tricyclic compounds as protein kinase inhibitors |
| SMT201800137T1 (en) | 2010-03-10 | 2018-07-17 | Incyte Holdings Corp | Piperidin-4-yl azetidine derivatives as jak1 inhibitors |
| PH12012502296B1 (en) | 2010-05-21 | 2017-10-06 | Incyte Holdings Corp | Topical formulation for a jak inhibitor |
| ES2536415T3 (en) | 2010-11-19 | 2015-05-25 | Incyte Corporation | Pyrrolopyridines and heterocyclic substituted pyrrolopyrimidines as JAK inhibitors |
| SG190839A1 (en) | 2010-11-19 | 2013-07-31 | Incyte Corp | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors |
| CN103476776B (en) * | 2011-01-07 | 2016-09-28 | 北京赛林泰医药技术有限公司 | 2,4-diaminourea-6,7-dihydro-5H-pyrrolo-[2,3] pyrimidine derivatives as FAK/Pyk2 inhibitor |
| CN102093364B (en) * | 2011-01-07 | 2015-01-28 | 北京赛林泰医药技术有限公司 | 2,4-diamido-6,7-dihydro-5H-pyrrolo [2,3] pyrimidine derivative as focal adhesion kinase/pyruvate kinase 2 (FAK/Pyk2) inhibitor |
| WO2012177606A1 (en) | 2011-06-20 | 2012-12-27 | Incyte Corporation | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors |
| TW201313721A (en) | 2011-08-18 | 2013-04-01 | Incyte Corp | Cyclohexyl azetidine derivatives as JAK inhibitors |
| UA111854C2 (en) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | METHODS AND INTERMEDIATE COMPOUNDS FOR JAK INHIBITORS |
| JP6182593B2 (en) | 2012-04-20 | 2017-08-16 | アドヴィーナス セラピューティクス リミテッド | Substituted heterobicyclic compounds, compositions and medicaments and uses thereof |
| WO2013173720A1 (en) | 2012-05-18 | 2013-11-21 | Incyte Corporation | Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors |
| PT2877467T (en) | 2012-07-26 | 2017-01-02 | Glaxo Group Ltd | 2-(azaindol-2-yl)benzimidazoles as pad4 inhibitors |
| JP6318156B2 (en) * | 2012-09-06 | 2018-04-25 | プレキシコン インコーポレーテッドPlexxikon Inc. | Compounds and methods for modulating kinases and indicators thereof |
| PE20151157A1 (en) | 2012-11-15 | 2015-08-19 | Incyte Corp | SUSTAINED RELEASE RUXOLITINIB DOSAGE FORMS |
| LT3489239T (en) | 2013-03-06 | 2022-03-10 | Incyte Holdings Corporation | JAK INHIBITOR MANUFACTURING METHODS AND INTERMEDIATES |
| CN105189481A (en) | 2013-03-13 | 2015-12-23 | 艾伯维公司 | Pyridine cdk9 kinase inhibitors |
| MX2015012386A (en) | 2013-03-13 | 2016-02-03 | Abbvie Inc | Cdk9 kinase inhibitors. |
| UY35419A (en) | 2013-03-14 | 2014-10-31 | Abbvie Inc | PIRROLO KINASA CDK9 INHIBITORS (2,3- B) PIRIDINE |
| CA2903538A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | Pyrrolopyrimindine cdk9 kinase inhibitors |
| BR112015023356A2 (en) | 2013-03-14 | 2017-07-18 | Abbvie Inc | pyrrol [2,3-b] pyridine cdk9 kinase inhibitors |
| UA120499C2 (en) | 2013-08-07 | 2019-12-26 | Інсайт Корпорейшн | TREATMENT OF DISEASES WITH THE USE OF DELAYED DOSAGE FORMS FOR JAK1 INHIBITOR |
| CN104804001B9 (en) * | 2014-01-24 | 2022-02-08 | 江苏柯菲平医药股份有限公司 | 4-substituted pyrrolo [2,3-d ] pyrimidine compounds and uses thereof |
| WO2015184305A1 (en) | 2014-05-30 | 2015-12-03 | Incyte Corporation | TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1 |
| US11512092B2 (en) | 2015-10-16 | 2022-11-29 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| SG10201913989QA (en) | 2015-10-16 | 2020-03-30 | Abbvie Inc | PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF |
| US11524964B2 (en) | 2015-10-16 | 2022-12-13 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US11365198B2 (en) | 2015-10-16 | 2022-06-21 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US11773106B2 (en) | 2015-10-16 | 2023-10-03 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US10550126B2 (en) | 2015-10-16 | 2020-02-04 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US12365689B2 (en) | 2015-10-16 | 2025-07-22 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| MX2019010733A (en) | 2017-03-09 | 2019-11-01 | Abbvie Inc | Methods of treating crohn's disease and ulcerative colitis. |
| US11564922B2 (en) | 2017-03-09 | 2023-01-31 | Abbvie Inc. | Methods of treating crohn's disease and ulcerative colitis |
| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| IL276302B2 (en) | 2018-01-30 | 2023-11-01 | Incyte Corp | Processes for preparing [1-(3-fluoro-2-tripluoromethyl(isonicotinyl)piperidine-one] |
| SMT202400306T1 (en) | 2018-03-30 | 2024-09-16 | Incyte Corp | Treatment of hidradenitis suppurativa using jak inhibitors |
| RS65335B1 (en) | 2018-10-05 | 2024-04-30 | Annapurna Bio Inc | Compounds and compositions for treating conditions associated with apj receptor activity |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE217873T1 (en) * | 1996-01-23 | 2002-06-15 | Novartis Erfind Verwalt Gmbh | PYRROLOPYRIMIDINES AND METHOD FOR THE PRODUCTION THEREOF |
| KR20000057228A (en) * | 1996-11-27 | 2000-09-15 | 디. 제이. 우드, 스피겔 알렌 제이 | Fused bicyclic pyrimidine derivatives |
| CZ20004727A3 (en) * | 1998-06-19 | 2002-03-13 | Pfizer Products Inc. | Derivatives of pyrrolo[2,3-d]pyrimidine |
| PA8474101A1 (en) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | PYROLEUM [2,3-D] PIRIMIDINE COMPOUNDS |
| CN1326457A (en) * | 1998-09-18 | 2001-12-12 | 巴斯福股份公司 | 4-aminopyrrolopyrimidines as kinase inhibitors |
| AU777911B2 (en) * | 1999-12-10 | 2004-11-04 | Pfizer Products Inc. | Pyrrolo(2,3-d)pyrimidine compounds |
-
2001
- 2001-06-23 GB GBGB0115393.1A patent/GB0115393D0/en not_active Ceased
-
2002
- 2002-06-21 EE EEP200400003A patent/EE05432B1/en not_active IP Right Cessation
- 2002-06-21 ME MEP-193/08A patent/MEP19308A/en unknown
- 2002-06-21 AU AU2002314325A patent/AU2002314325B8/en not_active Ceased
- 2002-06-21 HU HU0400300A patent/HUP0400300A3/en unknown
- 2002-06-21 EP EP02740895A patent/EP1404676A1/en not_active Withdrawn
- 2002-06-21 PL PL02374096A patent/PL374096A1/en not_active Application Discontinuation
- 2002-06-21 NZ NZ529766A patent/NZ529766A/en not_active IP Right Cessation
- 2002-06-21 CN CNB028119320A patent/CN1294135C/en not_active Expired - Fee Related
- 2002-06-21 CZ CZ20033443A patent/CZ20033443A3/en unknown
- 2002-06-21 TR TR2003/02242T patent/TR200302242T2/en unknown
- 2002-06-21 OA OA1200300335A patent/OA12632A/en unknown
- 2002-06-21 RS YU99203A patent/RS51698B/en unknown
- 2002-06-21 UA UA2004010502A patent/UA76760C2/en unknown
- 2002-06-21 JP JP2003507098A patent/JP4344607B2/en not_active Expired - Fee Related
- 2002-06-21 TN TNPCT/GB2002/002835A patent/TNSN03144A1/en unknown
- 2002-06-21 SK SK1588-2003A patent/SK15882003A3/en not_active Application Discontinuation
- 2002-06-21 BR BR0210652-3A patent/BR0210652A/en not_active Application Discontinuation
- 2002-06-21 WO PCT/GB2002/002835 patent/WO2003000695A1/en not_active Ceased
- 2002-06-21 EA EA200400073A patent/EA007415B1/en not_active IP Right Cessation
- 2002-06-21 CA CA002451932A patent/CA2451932C/en not_active Expired - Fee Related
-
2003
- 2003-12-23 EC EC2003004922A patent/ECSP034922A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2451932C (en) | 2009-12-29 |
| TR200302242T2 (en) | 2004-12-21 |
| CA2451932A1 (en) | 2003-01-03 |
| EP1404676A1 (en) | 2004-04-07 |
| CN1294135C (en) | 2007-01-10 |
| WO2003000695A1 (en) | 2003-01-03 |
| SK15882003A3 (en) | 2004-07-07 |
| JP4344607B2 (en) | 2009-10-14 |
| EE200400003A (en) | 2004-02-16 |
| PL374096A1 (en) | 2005-09-19 |
| CN1518552A (en) | 2004-08-04 |
| AU2002314325B2 (en) | 2009-01-08 |
| AU2002314325B8 (en) | 2009-01-29 |
| JP2005508300A (en) | 2005-03-31 |
| TNSN03144A1 (en) | 2005-12-23 |
| ECSP034922A (en) | 2004-04-28 |
| EA200400073A1 (en) | 2004-08-26 |
| MEP19308A (en) | 2010-06-10 |
| HUP0400300A3 (en) | 2010-12-28 |
| EE05432B1 (en) | 2011-06-15 |
| HUP0400300A2 (en) | 2007-08-28 |
| BR0210652A (en) | 2004-08-10 |
| RS51698B (en) | 2011-10-31 |
| UA76760C2 (en) | 2006-09-15 |
| WO2003000695A8 (en) | 2004-03-11 |
| EA007415B1 (en) | 2006-10-27 |
| NZ529766A (en) | 2008-11-28 |
| OA12632A (en) | 2006-06-14 |
| CZ20033443A3 (en) | 2004-03-17 |
| RS99203A (en) | 2006-12-15 |
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