|
WO1998005351A1
(en)
|
1996-08-08 |
1998-02-12 |
Amylin Pharmaceuticals, Inc. |
Methods for regulating gastrointestinal motility
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
IL128332A0
(en)
*
|
1996-08-30 |
2000-01-31 |
Novo Nordisk As |
GLP-1 derivatives
|
|
US7235627B2
(en)
|
1996-08-30 |
2007-06-26 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
US6268343B1
(en)
|
1996-08-30 |
2001-07-31 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
UA65549C2
(uk)
|
1996-11-05 |
2004-04-15 |
Елі Ліллі Енд Компані |
Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
|
|
US6380357B2
(en)
|
1997-12-16 |
2002-04-30 |
Eli Lilly And Company |
Glucagon-like peptide-1 crystals
|
|
EP1061946B1
(en)
*
|
1998-02-27 |
2004-04-28 |
Novo Nordisk A/S |
Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates
|
|
ATE466026T1
(de)
*
|
1998-02-27 |
2010-05-15 |
Novo Nordisk As |
Derivate von glp-1 und exendin mit verlängertem wirkdauer-profil
|
|
JP2002512175A
(ja)
|
1998-02-27 |
2002-04-23 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−1類似体の誘導体類
|
|
EP1062240B1
(en)
|
1998-02-27 |
2010-04-28 |
Novo Nordisk A/S |
N-terminally modified glp-1 derivatives
|
|
JP2003522099A
(ja)
|
1998-02-27 |
2003-07-22 |
ノボ ノルディスク アクティーゼルスカブ |
遅延作用プロファイルを有するglp−1のglp−1誘導体及びエキセンジン
|
|
AU2610599A
(en)
*
|
1998-02-27 |
1999-09-15 |
Novo Nordisk A/S |
N-terminally truncated glp-1 derivatives
|
|
JP4394279B2
(ja)
|
1998-03-09 |
2010-01-06 |
ジーランド ファーマ アクティーゼルスカブ |
酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体
|
|
AU5027299A
(en)
*
|
1998-07-31 |
2000-02-28 |
Novo Nordisk A/S |
Use of glp-1 and analogues for preventing type ii diabetes
|
|
WO2000012116A1
(en)
*
|
1998-08-28 |
2000-03-09 |
Eli Lilly And Company |
Method for administering insulinotropic peptides
|
|
US6720407B1
(en)
|
1998-08-28 |
2004-04-13 |
Eli Lilly And Company |
Method for administering insulinotropic peptides
|
|
EP1666054A1
(en)
*
|
1998-08-28 |
2006-06-07 |
Eli Lilly & Company |
Method for administering insulinotropic peptides
|
|
CN1317967A
(zh)
|
1998-09-17 |
2001-10-17 |
伊莱利利公司 |
蛋白质制剂
|
|
MY155270A
(en)
*
|
1998-09-24 |
2015-09-30 |
Lilly Co Eli |
Use of glp-1 or analogs in treatment of stroke
|
|
EP1359159A3
(en)
*
|
1998-12-07 |
2004-07-21 |
Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. |
Analogues of GLP-1
|
|
JP2002538081A
(ja)
|
1998-12-07 |
2002-11-12 |
ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス |
Glp−1の類似体
|
|
DE69922043T2
(de)
|
1998-12-07 |
2005-11-24 |
Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. |
Glp-1 analoge
|
|
NZ512663A
(en)
*
|
1999-01-14 |
2004-05-28 |
Amylin Pharmaceuticals Inc |
Novel exendin agonist formulations and methods of administration thereof
|
|
WO2000055203A1
(en)
|
1999-03-15 |
2000-09-21 |
Novo Nordisk A/S |
Ion exchange chromatographic separation of glp-1 and related peptides
|
|
US6451987B1
(en)
|
1999-03-15 |
2002-09-17 |
Novo Nordisk A/S |
Ion exchange chromatography of proteins and peptides
|
|
US6444788B1
(en)
|
1999-03-15 |
2002-09-03 |
Novo Nordisk A/S |
Ion exchange chromatography of GLP-1, analogs and derivatives thereof
|
|
US6451974B1
(en)
|
1999-03-17 |
2002-09-17 |
Novo Nordisk A/S |
Method of acylating peptides and novel acylating agents
|
|
JP4949557B2
(ja)
*
|
1999-03-17 |
2012-06-13 |
ノヴォ ノルディスク アー/エス |
ペプチドのアシル化方法及び新規アシル化剤
|
|
EP1956000B1
(en)
|
1999-03-17 |
2016-10-05 |
Novo Nordisk A/S |
Acylating agents useful for acylating peptides
|
|
JP2002544127A
(ja)
*
|
1999-04-30 |
2002-12-24 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
修飾されたエキセンジンおよびエキセンジン・アゴニスト
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
CA2363712C
(en)
|
1999-05-17 |
2011-05-10 |
Conjuchem Inc. |
Long lasting insulinotropic peptides
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
EP1076066A1
(en)
|
1999-07-12 |
2001-02-14 |
Zealand Pharmaceuticals A/S |
Peptides for lowering blood glucose levels
|
|
US6569832B1
(en)
|
1999-11-12 |
2003-05-27 |
Novo Nordisk A/S |
Inhibition of beta cell degeneration
|
|
EP1239871A1
(en)
*
|
1999-11-12 |
2002-09-18 |
Novo Nordisk A/S |
Use of glp-1 agonists for the inhibition of beta cell degeneration
|
|
US6844321B2
(en)
*
|
2000-01-31 |
2005-01-18 |
Novo Nordisk A/S |
Crystallization of a GLP-1 analogue
|
|
JP2003525908A
(ja)
|
2000-03-08 |
2003-09-02 |
ノボ ノルディスク アクティーゼルスカブ |
血清脂質の低下
|
|
DE10013895A1
(de)
|
2000-03-21 |
2001-10-04 |
Dmc2 Degussa Metals Catalysts Cerdec Ag |
Verfahren zur katalytischen Umsetzung von Kohlenmonoxid in einem Wasserstoff enthaltenden Gasgemisch
|
|
WO2002010195A2
(en)
*
|
2000-08-02 |
2002-02-07 |
Theratechnologies Inc. |
Modified peptides with increased potency
|
|
CA2430934C
(en)
|
2000-12-01 |
2011-06-21 |
Takeda Chemical Industries, Ltd. |
A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
|
|
BR0116024A
(pt)
*
|
2000-12-07 |
2005-12-13 |
Lilly Co Eli |
Proteìna de fusão heteróloga e uso da mesma
|
|
HRP20030498A2
(en)
|
2000-12-21 |
2005-04-30 |
Aventis Pharma Deutschland Gmbh |
Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
|
|
AU2002231688A1
(en)
|
2000-12-21 |
2002-07-01 |
Sanofi-Aventis Deutschland Gmbh |
Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
|
|
AU2002235731A1
(en)
|
2001-03-07 |
2002-09-19 |
Novo Nordisk A/S |
Combined use of derivatives of glp-1 analogs and ppar ligands
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
|
DE10142660A1
(de)
|
2001-08-31 |
2003-03-20 |
Aventis Pharma Gmbh |
Verwendung von Derivaten von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
|
|
EP1385867B1
(en)
*
|
2001-05-02 |
2006-08-30 |
Novo Nordisk A/S |
Preparation of bile acids
|
|
US6653492B2
(en)
|
2001-05-02 |
2003-11-25 |
Novo Nordick A/S |
Preparation of bile acids
|
|
PE20021091A1
(es)
|
2001-05-25 |
2003-02-04 |
Aventis Pharma Gmbh |
Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion
|
|
AU2002316811A1
(en)
|
2001-06-28 |
2003-03-03 |
Novo Nordisk A/S |
Stable formulation of modified glp-1
|
|
US20030082671A1
(en)
|
2001-07-24 |
2003-05-01 |
Thomas Hoeg-Jensen |
Method for making acylated polypeptides
|
|
US7595172B2
(en)
*
|
2001-07-24 |
2009-09-29 |
Novo Nordisk A/S |
Method for making acylated polypeptides
|
|
NZ531293A
(en)
|
2001-08-22 |
2005-08-26 |
Aventis Pharma Gmbh |
Pharamceuticals containing 1,4-benzothiepine-1,1-dioxide derivatives and another active substances such as ezetimibe, pamaqueside or tiqueside for treating lipid metabolism and atherosclerotic disorders
|
|
HRP20040199A2
(en)
|
2001-08-31 |
2005-04-30 |
Aventis Pharma Deutschland Gmbh |
Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators
|
|
DE10142667B4
(de)
|
2001-08-31 |
2004-06-09 |
Aventis Pharma Deutschland Gmbh |
C2-substituierte Indan-1-ole und ihre Derivate und ihre Verwendung als Arzneimittel
|
|
US6884812B2
(en)
|
2001-08-31 |
2005-04-26 |
Aventis Pharma Deutschland Gmbh |
Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
|
|
DE10142659A1
(de)
|
2001-08-31 |
2003-03-20 |
Aventis Pharma Gmbh |
Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
|
|
DE10142666A1
(de)
|
2001-08-31 |
2003-03-20 |
Aventis Pharma Gmbh |
Verwendung von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
|
|
DE10142665B4
(de)
|
2001-08-31 |
2004-05-06 |
Aventis Pharma Deutschland Gmbh |
C2-Disubstituierte Indan-1-one und ihre Derivate
|
|
DE10142668A1
(de)
|
2001-08-31 |
2003-03-20 |
Aventis Pharma Gmbh |
Verwendung von C2-substituierten Indan-1-on-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
|
|
DE10142662B4
(de)
|
2001-08-31 |
2004-07-08 |
Aventis Pharma Deutschland Gmbh |
Derivate von C2-substituierten Indan-1-ol-Systemen und ihre Verwendung als Arzneimittel
|
|
DE10142663B4
(de)
|
2001-08-31 |
2004-08-19 |
Aventis Pharma Deutschland Gmbh |
C2-Disubstituierte Indan-1-ol-Systeme
|
|
DE10142661B4
(de)
|
2001-08-31 |
2004-06-09 |
Aventis Pharma Deutschland Gmbh |
Mehrfach substituierte Indan-1-ol-Systeme und ihre Verwendung als Arzneimittel
|
|
DE10142722A1
(de)
|
2001-08-31 |
2003-03-27 |
Aventis Pharma Deutschland GmbH, 65929 Frankfurt |
C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US7399777B2
(en)
|
2001-08-31 |
2008-07-15 |
Sanofi-Aventis Deutschland Gmbh |
Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmceuticals
|
|
KR100989647B1
(ko)
|
2001-09-24 |
2010-10-26 |
오레곤 헬스 앤드 사이언스 유니버시티 |
식습관의 변화
|
|
EP2243776A1
(en)
|
2001-10-12 |
2010-10-27 |
High Point Pharmaceuticals, LLC |
Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor
|
|
CA2463908A1
(en)
|
2001-10-18 |
2003-04-24 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
US7238671B2
(en)
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
WO2003055482A1
(en)
|
2001-12-21 |
2003-07-10 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
|
JP2005518408A
(ja)
|
2001-12-29 |
2005-06-23 |
ノボ ノルディスク アクティーゼルスカブ |
異常脂肪血症を治療するための、glp−1化合物と他の薬物との組み合わせ使用
|
|
MXPA04006679A
(es)
*
|
2002-01-08 |
2004-11-10 |
Lilly Co Eli |
Analogos extendidos de peptido-1 de tipo glucagon.
|
|
EP1474163A2
(en)
*
|
2002-01-10 |
2004-11-10 |
Imperial College Innovations Limited |
Modification of feeding behavior
|
|
US8058233B2
(en)
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
CN1332711C
(zh)
|
2002-02-20 |
2007-08-22 |
埃米球科技有限公司 |
施用glp-1分子的方法
|
|
US7223796B2
(en)
|
2002-04-11 |
2007-05-29 |
Sanofi-Aventis Deutschland Gmbh |
Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
|
|
US7049341B2
(en)
|
2002-06-07 |
2006-05-23 |
Aventis Pharma Deutschland Gmbh |
N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use
|
|
US7176193B2
(en)
|
2002-06-19 |
2007-02-13 |
Sanofi-Aventis Deutschland Gmbh |
Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
|
|
US7176194B2
(en)
|
2002-06-19 |
2007-02-13 |
Sanofi-Aventis Deutschland Gmbh |
Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
|
|
US7671047B2
(en)
|
2002-06-19 |
2010-03-02 |
Sanofi-Aventis Deutschland Gmbh |
Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
|
|
BR0312023A
(pt)
|
2002-06-27 |
2005-03-22 |
Novo Nordisk As |
Composto, composto ativador da glicose cinase, método para evitar a hipoglicemia, uso de um composto, e, composição farmacêutica
|
|
EP1525219B1
(en)
*
|
2002-07-04 |
2009-05-27 |
Zealand Pharma A/S |
Glp-1 and methods for treating diabetes
|
|
US7262220B2
(en)
|
2002-07-11 |
2007-08-28 |
Sanofi-Aventis Deutschland Gmbh |
Urea- and urethane-substituted acylureas, process for their preparation and their use
|
|
DE10231370B4
(de)
|
2002-07-11 |
2006-04-06 |
Sanofi-Aventis Deutschland Gmbh |
Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
|
RS20050019A
(sr)
|
2002-07-12 |
2007-09-21 |
Sanofi - Aventis Pharma Deutschland Gmbh., |
Heterociklično supstituisani benzoilkarbamidi,postupak za njihovu proizvodnju i njihova primena kao leka
|
|
US7141561B2
(en)
|
2002-07-25 |
2006-11-28 |
Sanofi-Aventis Deutschland Gmbh |
Substituted diaryl heterocycles, process for their preparation and their use as medicaments
|
|
US8821915B2
(en)
|
2002-08-09 |
2014-09-02 |
Veroscience, Llc |
Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
|
|
CA2500123A1
(en)
*
|
2002-09-25 |
2004-04-08 |
Novo Nordisk A/S |
Method for producing acylated peptides
|
|
CA2500021A1
(en)
*
|
2002-09-25 |
2004-04-08 |
Theratechnologies Inc. |
Modified glp-1 peptides with increased biological potency
|
|
US7273921B2
(en)
|
2002-09-25 |
2007-09-25 |
Novo Nordisk A/S |
Method for producing acylated peptides
|
|
US20040157922A1
(en)
|
2002-10-04 |
2004-08-12 |
Aventis Pharma Deutschland Gmbh |
Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
|
|
US7208504B2
(en)
|
2002-10-12 |
2007-04-24 |
Sanofi-Aventis Deutschland Gmbh |
Bicyclic inhibitors of hormone sensitive lipase
|
|
WO2004035624A2
(en)
*
|
2002-10-14 |
2004-04-29 |
Novo Nordisk A/S |
Glucagon - like peptide - 2 variants
|
|
DE10258007B4
(de)
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
|
US7655618B2
(en)
|
2002-12-27 |
2010-02-02 |
Diobex, Inc. |
Compositions and methods for the prevention and control of insulin-induced hypoglycemia
|
|
CA2509755A1
(en)
|
2002-12-27 |
2004-07-22 |
Diobex, Inc. |
Compositions and methods for the prevention and control of insulin-induced hypoglycemia
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
US20040242583A1
(en)
|
2003-01-20 |
2004-12-02 |
Aventis Pharma Deutschland Gmbh |
Pyrimido[5,4-e][1,2,4]triazine-5,7-diones, processes for preparing them and their use
|
|
US7179941B2
(en)
|
2003-01-23 |
2007-02-20 |
Sanofi-Aventis Deutschland Gmbh |
Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
|
|
DE602004031927D1
(de)
|
2003-02-04 |
2011-05-05 |
Novo Nordisk As |
Injektionsvorrichtung mit drehbarer dosiseinstellungsvorrichtung
|
|
US7390814B2
(en)
|
2003-02-13 |
2008-06-24 |
Sanofi-Aventis Deutschland Gmbh |
Substituted hexahydropyrazino [1,2-a] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments
|
|
US7652007B2
(en)
|
2003-02-13 |
2010-01-26 |
Sanofi-Aventis Deutschland Gmbh |
Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments
|
|
DE10306250A1
(de)
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
DE10308352A1
(de)
|
2003-02-27 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
|
|
DE10308355A1
(de)
|
2003-02-27 |
2004-12-23 |
Aventis Pharma Deutschland Gmbh |
Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
|
|
DE10308351A1
(de)
|
2003-02-27 |
2004-11-25 |
Aventis Pharma Deutschland Gmbh |
1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
DE10308353A1
(de)
|
2003-02-27 |
2004-12-02 |
Aventis Pharma Deutschland Gmbh |
Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US7148246B2
(en)
|
2003-02-27 |
2006-12-12 |
Sanofi-Aventis Deutschland Gmbh |
Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
|
|
WO2004078195A1
(ja)
|
2003-03-07 |
2004-09-16 |
Ajinomoto Co., Inc. |
腸管細胞のインスリン産生細胞への変換誘導剤、及び糖尿病治療剤
|
|
US7501440B2
(en)
|
2003-03-07 |
2009-03-10 |
Sanofi-Aventis Deutschland Gmbh |
Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use
|
|
EP1605897B1
(en)
|
2003-03-19 |
2012-07-25 |
Eli Lilly And Company |
Polyethelene glycol link glp-1 compounds
|
|
CN102134577A
(zh)
|
2003-03-28 |
2011-07-27 |
独立行政法人农业生物资源研究所 |
高产重组蛋白的植物贮藏器官的生产方法以及新型重组蛋白
|
|
DE10314610A1
(de)
|
2003-04-01 |
2004-11-04 |
Aventis Pharma Deutschland Gmbh |
Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
|
|
ATE467616T1
(de)
|
2003-04-11 |
2010-05-15 |
High Point Pharmaceuticals Llc |
Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase
|
|
EP1617888B1
(en)
|
2003-04-23 |
2019-06-12 |
Valeritas, Inc. |
Hydraulically actuated pump for long duration medicament administration
|
|
EP1633391B1
(en)
|
2003-06-03 |
2011-10-19 |
Novo Nordisk A/S |
Stabilized pharmaceutical peptide compositions
|
|
ATE541582T1
(de)
|
2003-06-03 |
2012-02-15 |
Novo Nordisk As |
Stabilisierte pharmazeutische glp-1 peptid zusammensetzungen
|
|
EP1664108B1
(en)
|
2003-08-21 |
2009-10-14 |
Novo Nordisk A/S |
Separation of polypeptides comprising a racemized amino acid
|
|
WO2005023291A2
(en)
*
|
2003-09-11 |
2005-03-17 |
Novo Nordisk A/S |
Use of glp1-agonists in the treatment of patients with type i diabetes
|
|
CN100444898C
(zh)
*
|
2003-09-19 |
2008-12-24 |
诺沃挪第克公司 |
治疗肽的清蛋白结合型衍生物
|
|
EP1684793B1
(en)
*
|
2003-11-13 |
2011-09-21 |
Novo Nordisk A/S |
Pharmaceutical composition comprising an insulinotropic glp-1(7-37) analogue, asp(b28)-insulin, and a surfactant
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
TR201906789T4
(tr)
|
2003-11-20 |
2019-05-21 |
Novo Nordisk As |
Üretim ve enjeksiyon cihazlarında kullanım için en uygun olan propilen glikol ihtiva eden peptit formülasyonları.
|
|
ATE498404T1
(de)
|
2003-12-09 |
2011-03-15 |
Novo Nordisk As |
Regulierung der nahrungspräferenz mit glp-1- agonisten
|
|
EP1711523B1
(en)
*
|
2003-12-16 |
2012-10-10 |
Ipsen Pharma |
Analogues of glp-1
|
|
US7521527B2
(en)
|
2003-12-16 |
2009-04-21 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
GLP-1 pharmaceutical compositions
|
|
MXPA06006745A
(es)
|
2003-12-18 |
2006-08-18 |
Novo Nordisk As |
Compuestos glp-1 novedosos.
|
|
US20060286129A1
(en)
|
2003-12-19 |
2006-12-21 |
Emisphere Technologies, Inc. |
Oral GLP-1 formulations
|
|
JP4834840B2
(ja)
|
2004-01-06 |
2011-12-14 |
ノヴォ ノルディスク アー/エス |
ヘテロアリール尿素およびグルコキナーゼ活性化剤としてのその使用
|
|
US7538185B2
(en)
|
2004-01-08 |
2009-05-26 |
Theratechnologies Inc. |
Glucagon-like peptide-1 analogs with long duration of action
|
|
EP2033662B1
(en)
|
2004-01-21 |
2012-10-17 |
Novo Nordisk Health Care AG |
Transglutaminase mediated conjugation of peptides
|
|
US7241787B2
(en)
|
2004-01-25 |
2007-07-10 |
Sanofi-Aventis Deutschland Gmbh |
Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
|
|
US7470706B2
(en)
|
2004-01-31 |
2008-12-30 |
Sanofi-Aventis Deutschland Gmbh |
Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
|
|
US7498341B2
(en)
|
2004-01-31 |
2009-03-03 |
Sanofi Aventis Deutschland Gmbh |
Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
|
|
US7402674B2
(en)
|
2004-01-31 |
2008-07-22 |
Sanofi-Aventis Deutschland Gmbh, |
7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
|
|
DE102004005172A1
(de)
|
2004-02-02 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
|
|
KR100564618B1
(ko)
|
2004-03-11 |
2006-03-28 |
삼성전자주식회사 |
디스크 드라이브의 층간 탐색 방법
|
|
EP1586573B1
(en)
|
2004-04-01 |
2007-02-07 |
Sanofi-Aventis Deutschland GmbH |
Oxadiazolones, processes for their preparation and their use as pharmaceuticals
|
|
GT200500063A
(es)
|
2004-04-01 |
2005-10-14 |
|
Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
|
|
EP1604988A1
(en)
|
2004-05-18 |
2005-12-14 |
Sanofi-Aventis Deutschland GmbH |
Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals
|
|
JP2008501765A
(ja)
|
2004-06-11 |
2008-01-24 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−1アゴニストを用いた薬剤誘発性肥満の中和
|
|
WO2006014425A1
(en)
|
2004-07-02 |
2006-02-09 |
Biovalve Technologies, Inc. |
Methods and devices for delivering glp-1 and uses thereof
|
|
US8710181B2
(en)
|
2004-08-31 |
2014-04-29 |
Novo Nordisk A/S |
Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
|
|
EP1841749A1
(en)
|
2004-09-02 |
2007-10-10 |
Metabasis Therapeutics, Inc. |
Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
|
|
US8030273B2
(en)
|
2004-10-07 |
2011-10-04 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
|
US7893017B2
(en)
|
2004-10-07 |
2011-02-22 |
Novo Nordisk A/S |
Protracted GLP-1 compounds
|
|
RU2413530C9
(ru)
*
|
2004-11-12 |
2021-05-18 |
Ново Нордиск А/С |
Стабильные препараты инсулинотропных пептидов
|
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
|
CN101137631A
(zh)
|
2004-12-03 |
2008-03-05 |
转化技术制药公司 |
杂芳族葡糖激酶激活剂
|
|
TWI376234B
(en)
*
|
2005-02-01 |
2012-11-11 |
Msd Oss Bv |
Conjugates of a polypeptide and an oligosaccharide
|
|
EP1846447B1
(en)
|
2005-02-02 |
2013-08-21 |
Novo Nordisk A/S |
Insulin derivatives
|
|
WO2006082204A1
(en)
|
2005-02-02 |
2006-08-10 |
Novo Nordisk A/S |
Insulin derivatives
|
|
JP5755398B2
(ja)
|
2005-03-18 |
2015-07-29 |
ノヴォ ノルディスク アー/エス |
伸長されたglp−1化合物
|
|
US8840586B2
(en)
|
2006-08-23 |
2014-09-23 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir filling and infusion medium delivery
|
|
US7905868B2
(en)
|
2006-08-23 |
2011-03-15 |
Medtronic Minimed, Inc. |
Infusion medium delivery device and method with drive device for driving plunger in reservoir
|
|
US8277415B2
(en)
|
2006-08-23 |
2012-10-02 |
Medtronic Minimed, Inc. |
Infusion medium delivery device and method with drive device for driving plunger in reservoir
|
|
US8512288B2
(en)
|
2006-08-23 |
2013-08-20 |
Medtronic Minimed, Inc. |
Infusion medium delivery device and method with drive device for driving plunger in reservoir
|
|
US7686787B2
(en)
|
2005-05-06 |
2010-03-30 |
Medtronic Minimed, Inc. |
Infusion device and method with disposable portion
|
|
US8137314B2
(en)
|
2006-08-23 |
2012-03-20 |
Medtronic Minimed, Inc. |
Infusion medium delivery device and method with compressible or curved reservoir or conduit
|
|
US20080097291A1
(en)
|
2006-08-23 |
2008-04-24 |
Hanson Ian B |
Infusion pumps and methods and delivery devices and methods with same
|
|
EP1889618A4
(en)
*
|
2005-05-27 |
2010-11-24 |
Daiichi Sankyo Co Ltd |
Combined drug for treating diabetes
|
|
DE102005026762A1
(de)
|
2005-06-09 |
2006-12-21 |
Sanofi-Aventis Deutschland Gmbh |
Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
|
|
ES2372617T3
(es)
|
2005-06-30 |
2012-01-24 |
High Point Pharmaceuticals, Llc |
Ácidos fenoxiacéticos como activadores de ppar-delta.
|
|
RU2499795C2
(ru)
|
2005-07-04 |
2013-11-27 |
Хай Пойнт Фармасьютикалс, ЛЛС |
Антагонисты гистаминовых н3-рецепторов
|
|
US7884210B2
(en)
|
2005-07-14 |
2011-02-08 |
Novo Nordisk A/S |
Ureido-thiazole glucokinase activators
|
|
EP1910317B1
(en)
|
2005-07-20 |
2013-07-03 |
Eli Lilly And Company |
1-amino linked compounds
|
|
PL1767545T3
(pl)
|
2005-09-22 |
2010-04-30 |
Biocompatibles Uk Ltd |
Polipeptydy fuzyjne GLP-1 (glukagonopodobny peptyd-1) o zwiększonej odporności na peptydazy
|
|
ES2393757T3
(es)
|
2005-11-17 |
2012-12-27 |
Eli Lilly & Company |
Antagonistas de receptor de glucagón, preparación y usos terapéuticos
|
|
JP5096363B2
(ja)
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Glp−1のポリマ複合体
|
|
CN103224477A
(zh)
|
2005-12-22 |
2013-07-31 |
高点制药有限责任公司 |
作为PPAR-δ活化剂的苯氧基乙酸
|
|
MX2008009125A
(es)
|
2006-01-18 |
2008-10-23 |
Qps Llc |
Composiciones farmaceuticas con estabilidad mejorada.
|
|
US11027058B2
(en)
|
2006-02-09 |
2021-06-08 |
Deka Products Limited Partnership |
Infusion pump assembly
|
|
US11478623B2
(en)
|
2006-02-09 |
2022-10-25 |
Deka Products Limited Partnership |
Infusion pump assembly
|
|
US12151080B2
(en)
|
2006-02-09 |
2024-11-26 |
Deka Products Limited Partnership |
Adhesive and peripheral systems and methods for medical devices
|
|
CN103736165B
(zh)
|
2006-02-09 |
2017-05-10 |
德卡产品有限公司 |
流体分配器件、流体流的测量方法和系统及流体输送系统
|
|
US11497846B2
(en)
|
2006-02-09 |
2022-11-15 |
Deka Products Limited Partnership |
Patch-sized fluid delivery systems and methods
|
|
US11364335B2
(en)
|
2006-02-09 |
2022-06-21 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
US12274857B2
(en)
|
2006-02-09 |
2025-04-15 |
Deka Products Limited Partnership |
Method and system for shape-memory alloy wire control
|
|
US12370305B2
(en)
|
2006-02-09 |
2025-07-29 |
Deka Products Limited Partnership |
Patch-sized fluid delivery systems and methods
|
|
US12070574B2
(en)
|
2006-02-09 |
2024-08-27 |
Deka Products Limited Partnership |
Apparatus, systems and methods for an infusion pump assembly
|
|
US11318249B2
(en)
|
2006-02-09 |
2022-05-03 |
Deka Products Limited Partnership |
Infusion pump assembly
|
|
AU2007225088B2
(en)
|
2006-03-13 |
2012-09-13 |
Kyorin Pharmaceutical Co., Ltd |
Aminoquinolones as GSK-3 inhibitors
|
|
JP5312054B2
(ja)
|
2006-03-15 |
2013-10-09 |
ノボ・ノルデイスク・エー/エス |
アミリンとインスリンの混合物
|
|
MX2008011123A
(es)
|
2006-03-28 |
2008-09-30 |
High Point Pharmaceuticals Llc |
Benzotiazoles que tienen actividad de receptor h3 de histamina.
|
|
CN103239773B
(zh)
|
2006-03-30 |
2015-08-26 |
瓦莱里塔斯公司 |
多筒式流体递送器械
|
|
EP2049475B1
(en)
|
2006-04-24 |
2012-02-01 |
Eli Lilly & Company |
Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
|
ATE444741T1
(de)
|
2006-05-10 |
2009-10-15 |
Biocompatibles Uk Ltd |
Glp-1 peptide enthaltende kugelförmige mikrokapseln, deren produktion und deren verwendung
|
|
SG163547A1
(en)
|
2006-05-29 |
2010-08-30 |
High Point Pharmaceuticals Llc |
3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist
|
|
DE102006028862A1
(de)
|
2006-06-23 |
2007-12-27 |
Merck Patent Gmbh |
3-Amino-imidazo[1,2-a]pyridinderivate
|
|
EP2054073B1
(en)
|
2006-07-11 |
2014-11-26 |
Foresee Pharmaceuticals, Inc. |
Pharmaceutical compositions for sustained release delivery of peptides
|
|
AU2007275294A1
(en)
|
2006-07-18 |
2008-01-24 |
Centocor, Inc. |
Human GLP-1 mimetibodies, compositions, methods and uses
|
|
JP2010500300A
(ja)
|
2006-08-08 |
2010-01-07 |
サノフィ−アベンティス |
アリールアミノアリール−アルキル−置換イミダゾリジン−2,4−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
|
|
US7736338B2
(en)
|
2006-08-23 |
2010-06-15 |
Medtronic Minimed, Inc. |
Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
|
|
US7828764B2
(en)
|
2006-08-23 |
2010-11-09 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir filling and infusion medium delivery
|
|
US7811262B2
(en)
|
2006-08-23 |
2010-10-12 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir filling and infusion medium delivery
|
|
US7794434B2
(en)
|
2006-08-23 |
2010-09-14 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir filling and infusion medium delivery
|
|
WO2008025856A2
(en)
|
2006-09-01 |
2008-03-06 |
Novo Nordisk Health Care Ag |
Modified glycoproteins
|
|
JP2010502670A
(ja)
|
2006-09-07 |
2010-01-28 |
ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング |
真性糖尿病のための組合せ治療
|
|
ES2377322T3
(es)
|
2006-11-15 |
2012-03-26 |
High Point Pharmaceuticals, Llc |
Nuevas 2-(2-hidroxifenil)benzotiadiazinas útiles para el tratamiento de la obesidad y la diabetes
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
WO2008084044A1
(en)
|
2007-01-11 |
2008-07-17 |
Novo Nordisk A/S |
Urea glucokinase activators
|
|
DE102007002260A1
(de)
|
2007-01-16 |
2008-07-31 |
Sanofi-Aventis |
Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
JP2010517700A
(ja)
|
2007-02-09 |
2010-05-27 |
デカ・プロダクツ・リミテッド・パートナーシップ |
自動挿入アセンブリ
|
|
DE102007008420A1
(de)
|
2007-02-21 |
2008-08-28 |
Merck Patent Gmbh |
Benzimidazolderivate
|
|
EP1975176A1
(en)
*
|
2007-03-27 |
2008-10-01 |
Biocompatibles UK Limited |
Novel glp-1 fusion peptides, their production and use
|
|
US8613725B2
(en)
|
2007-04-30 |
2013-12-24 |
Medtronic Minimed, Inc. |
Reservoir systems and methods
|
|
US8323250B2
(en)
|
2007-04-30 |
2012-12-04 |
Medtronic Minimed, Inc. |
Adhesive patch systems and methods
|
|
US7963954B2
(en)
|
2007-04-30 |
2011-06-21 |
Medtronic Minimed, Inc. |
Automated filling systems and methods
|
|
US7959715B2
(en)
|
2007-04-30 |
2011-06-14 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir air bubble management
|
|
US8434528B2
(en)
|
2007-04-30 |
2013-05-07 |
Medtronic Minimed, Inc. |
Systems and methods for reservoir filling
|
|
US8597243B2
(en)
|
2007-04-30 |
2013-12-03 |
Medtronic Minimed, Inc. |
Systems and methods allowing for reservoir air bubble management
|
|
WO2008136845A2
(en)
|
2007-04-30 |
2008-11-13 |
Medtronic Minimed, Inc. |
Reservoir filling, bubble management, and infusion medium delivery systems and methods with same
|
|
ES2465216T3
(es)
|
2007-06-04 |
2014-06-05 |
Ben Gurion University Of The Negev Research And Development Authority |
Compuestos de triarilo y composiciones que comprenden los mismos
|
|
US20080319221A1
(en)
|
2007-06-22 |
2008-12-25 |
Bernd Junker |
Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
|
|
JP2009019027A
(ja)
*
|
2007-07-16 |
2009-01-29 |
Hanmi Pharmaceutical Co Ltd |
アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
|
|
WO2009010428A1
(en)
|
2007-07-16 |
2009-01-22 |
Novo Nordisk A/S |
Protease stabilized, pegylated insulin analogues
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2009030774A1
(en)
*
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
|
EP2190872B1
(en)
*
|
2007-09-05 |
2018-03-14 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
|
US20100261637A1
(en)
|
2007-09-05 |
2010-10-14 |
Novo Nordisk A/S |
Peptides derivatized with a-b-c-d- and their therapeutical use
|
|
WO2009035634A2
(en)
|
2007-09-11 |
2009-03-19 |
Activx Biosciences, Inc. |
Cyanoaminoquinolones and tetrazoloaminoquinolones as gsk-3 inhibitors
|
|
CN102344457B
(zh)
|
2007-09-12 |
2015-07-22 |
杏林制药株式会社 |
作为 gsk-3 抑制剂的螺环状氨基喹诺酮
|
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
|
DE102007054497B3
(de)
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
|
JP5241849B2
(ja)
|
2007-11-16 |
2013-07-17 |
ノボ・ノルデイスク・エー/エス |
インスリン及びインスリン分泌性ペプチドを含む薬学的組成物
|
|
US20100317057A1
(en)
|
2007-12-28 |
2010-12-16 |
Novo Nordisk A/S |
Semi-recombinant preparation of glp-1 analogues
|
|
US10080704B2
(en)
|
2007-12-31 |
2018-09-25 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
US10188787B2
(en)
|
2007-12-31 |
2019-01-29 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
US8491570B2
(en)
|
2007-12-31 |
2013-07-23 |
Deka Products Limited Partnership |
Infusion pump assembly
|
|
US8900188B2
(en)
|
2007-12-31 |
2014-12-02 |
Deka Products Limited Partnership |
Split ring resonator antenna adapted for use in wirelessly controlled medical device
|
|
US9456955B2
(en)
|
2007-12-31 |
2016-10-04 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
US8881774B2
(en)
|
2007-12-31 |
2014-11-11 |
Deka Research & Development Corp. |
Apparatus, system and method for fluid delivery
|
|
US12447265B2
(en)
|
2007-12-31 |
2025-10-21 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
AU2008347241B2
(en)
|
2007-12-31 |
2014-09-18 |
Deka Products Limited Partnership |
Infusion pump assembly
|
|
DE102008003568A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
EP2229406B1
(de)
|
2008-01-09 |
2015-04-22 |
Sanofi-Aventis Deutschland GmbH |
Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
|
|
DE102008003566A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008025007A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
CN102007143B
(zh)
|
2008-01-09 |
2015-08-26 |
塞诺菲-安万特德国有限公司 |
具有超延迟时效特征的新型胰岛素衍生物
|
|
DE102008025008A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
WO2009109927A2
(en)
*
|
2008-03-05 |
2009-09-11 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Glp-1 receptor agonists and related active pharmaceutical ingredients for treatment of cancer
|
|
CN102037008B
(zh)
|
2008-03-18 |
2016-08-31 |
诺沃-诺迪斯克有限公司 |
蛋白酶稳定化的、酰化胰岛素类似物
|
|
DE102008017590A1
(de)
|
2008-04-07 |
2009-10-08 |
Merck Patent Gmbh |
Glucopyranosidderivate
|
|
CN101555214B
(zh)
|
2008-04-08 |
2012-07-11 |
北京嘉事联博医药科技有限公司 |
苯基环丁基酰胺衍生物及其光学异构体、制备方法和用途
|
|
EP3412300A1
(en)
|
2008-06-27 |
2018-12-12 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
KR20110039348A
(ko)
|
2008-08-06 |
2011-04-15 |
노보 노르디스크 헬스 케어 악티엔게젤샤프트 |
연장된 생체내 효능을 가지는 콘쥬게이트된 단백질
|
|
US8637647B2
(en)
|
2008-09-12 |
2014-01-28 |
Novo Nordisk A/S |
Method of acylating a peptide or protein
|
|
CA3037726C
(en)
|
2008-09-15 |
2021-11-16 |
Deka Products Limited Partnership |
Systems and methods for fluid delivery
|
|
CN102256618A
(zh)
|
2008-10-17 |
2011-11-23 |
赛诺菲-安万特德国有限公司 |
胰岛素和glp-1激动剂的组合
|
|
DE102008051834A1
(de)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008053048A1
(de)
|
2008-10-24 |
2010-04-29 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102009038210A1
(de)
|
2009-08-20 |
2011-03-03 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
WO2010054326A2
(en)
|
2008-11-07 |
2010-05-14 |
The General Hospital Corporation |
C-terminal fragments of glucagon-like peptide-1 (glp-1)
|
|
IT1392655B1
(it)
|
2008-11-20 |
2012-03-16 |
Bio Ker S R L |
Site-specific monoconjugated insulinotropic glp-1 peptides.
|
|
JP2012509879A
(ja)
|
2008-11-21 |
2012-04-26 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
アダマンチルベンズアミド化合物
|
|
CA2745524C
(en)
|
2008-12-05 |
2020-06-09 |
Angiochem Inc. |
Conjugates of neurotensin or neurotensin analogs and uses thereof
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
US8685919B2
(en)
|
2008-12-15 |
2014-04-01 |
Zealand Pharma A/S |
Glucagon analogues
|
|
KR20110126592A
(ko)
|
2008-12-15 |
2011-11-23 |
질랜드 파마 에이/에스 |
글루카곤 유사체
|
|
JP5635531B2
(ja)
|
2008-12-15 |
2014-12-03 |
ジーランド ファーマ アクティーゼルスカブ |
グルカゴン類似体
|
|
WO2010070255A1
(en)
|
2008-12-15 |
2010-06-24 |
Zealand Pharma A/S |
Glucagon analogues
|
|
JP5816097B2
(ja)
|
2009-01-22 |
2015-11-18 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
安定な成長ホルモン化合物
|
|
BRPI1007313A2
(pt)
|
2009-01-23 |
2016-02-10 |
Novo Nordisk As |
derivados de fgf21 com ligante de albumina a-b-c-d-e e seu uso.
|
|
CN101824087A
(zh)
*
|
2009-03-05 |
2010-09-08 |
连云港恒邦医药科技有限公司 |
胰高血糖素样肽-2类似物及其制备方法和用途
|
|
BRPI1008974A2
(pt)
|
2009-03-11 |
2017-06-06 |
Kyorin Seiyaku Kk |
composto, composição farmacêutica, e, método para tratar, prevenir ou melhorar uma doença mediada com gsk-3
|
|
US9352025B2
(en)
|
2009-06-05 |
2016-05-31 |
Veroscience Llc |
Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
|
|
EP2437732B1
(en)
*
|
2009-06-05 |
2018-05-09 |
VeroScience LLC |
Combination of dopamine agonists plus first phase insulin secretagouges for the treatment of metabolic disorders
|
|
AU2014265118B2
(en)
*
|
2009-06-05 |
2016-11-17 |
Veroscience Llc |
Combination of dopamine agonists plus first phase insulin secretagouges for the treatment of metabolic disorders
|
|
EP2440235A1
(en)
*
|
2009-06-11 |
2012-04-18 |
Novo Nordisk A/S |
Glp-1 and fgf21 combinations for treatment of diabetes type 2
|
|
PL2451437T3
(pl)
|
2009-07-06 |
2017-05-31 |
Sanofi-Aventis Deutschland Gmbh |
Wodne preparaty insuliny zawierające metioninę
|
|
AP3329A
(en)
|
2009-07-13 |
2015-06-30 |
Zealand Pharma As |
Acylated glucagon analogues
|
|
EP2453948B1
(en)
|
2009-07-15 |
2015-02-18 |
DEKA Products Limited Partnership |
Apparatus, systems and methods for an infusion pump assembly
|
|
US8614182B2
(en)
|
2009-07-30 |
2013-12-24 |
Jiangsu Hansoh Pharmaceuticals Co., Ltd. |
GLP-1 analogues and their pharmaceutical salts and uses
|
|
CN101987868B
(zh)
*
|
2009-07-30 |
2013-09-04 |
江苏豪森医药集团有限公司 |
Glp-1类似物的衍生物或其可药用盐和用途
|
|
JP6086528B2
(ja)
|
2009-08-06 |
2017-03-01 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
長期のインビボ有効性を有する成長ホルモン
|
|
MX2012001729A
(es)
|
2009-08-26 |
2012-06-13 |
Sanofi Sa |
Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
|
|
KR20120091174A
(ko)
|
2009-10-02 |
2012-08-17 |
사노피 |
골질환 치료제의 제조를 위한 sglt-1/sglt-2 억제제 활성을 갖는 화합물의 용도
|
|
WO2011048614A2
(en)
|
2009-10-22 |
2011-04-28 |
Cadila Healthcare Limited |
Short chain peptidomimetics based orally active glp-1 agonist and glucagon receptor antagonist
|
|
TR201809460T4
(tr)
|
2009-11-13 |
2018-07-23 |
Sanofi Aventis Deutschland |
Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim.
|
|
NZ599847A
(en)
|
2009-11-13 |
2013-09-27 |
Sanofi Aventis Deutschland |
Pharmaceutical composition comprising a glp-1 agonist and methionine
|
|
EP2512518A1
(en)
|
2009-12-16 |
2012-10-24 |
Novo Nordisk A/S |
Glp-1 receptor agonist compounds with a modified n-terminus
|
|
CA3033439C
(en)
|
2010-01-22 |
2021-04-06 |
Deka Products Limited Partnership |
Method and system for shape-memory alloy wire control
|
|
JP5980689B2
(ja)
|
2010-01-22 |
2016-08-31 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
安定な成長ホルモン化合物
|
|
CN118767117A
(zh)
|
2010-01-22 |
2024-10-15 |
诺沃—诺迪斯克保健股份有限公司 |
体内功效延长的生长激素
|
|
EP2539364A1
(en)
|
2010-02-26 |
2013-01-02 |
Novo Nordisk A/S |
Peptides for treatment of obesity
|
|
BR112012021231A2
(pt)
|
2010-02-26 |
2015-09-08 |
Basf Plant Science Co Gmbh |
método para acentuar o rendimento em plantas, planta, construto, uso de um construto, método para a produção de uma planta transgênica, partes coletáveis de uma planta, produtos derivados de uma planta, uso de um ácido nucleíco e método para a produção de um produto
|
|
JP5992836B2
(ja)
|
2010-03-01 |
2016-09-14 |
ノヴォ ノルディスク アー/エス |
ペプチドを精製するための分取rp−hplc法
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2552950A1
(en)
|
2010-03-26 |
2013-02-06 |
Novo Nordisk A/S |
Novel glucagon analogues
|
|
US9168288B2
(en)
|
2010-04-09 |
2015-10-27 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a GLP-1 agonist
|
|
DE102010015123A1
(de)
|
2010-04-16 |
2011-10-20 |
Sanofi-Aventis Deutschland Gmbh |
Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
EA023925B1
(ru)
|
2010-04-27 |
2016-07-29 |
Зилэнд Фарма А/С |
Пептидные конъюгаты агонистов рецептора glp-1 и их применение
|
|
WO2011136361A1
(ja)
|
2010-04-30 |
2011-11-03 |
株式会社 三和化学研究所 |
生理活性物質等の生体内安定性向上のためのペプチド及び生体内安定性が向上した生理活性物質
|
|
WO2011157827A1
(de)
|
2010-06-18 |
2011-12-22 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
UY33462A
(es)
|
2010-06-23 |
2012-01-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
PH12012502472A1
(en)
|
2010-06-24 |
2013-03-25 |
Zealand Pharma As |
Glucagon analogues
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
WO2012028172A1
(en)
|
2010-08-30 |
2012-03-08 |
Sanofi-Aventis Deutschland Gmbh |
Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
|
|
US9040481B2
(en)
|
2010-11-02 |
2015-05-26 |
The General Hospital Corporation |
Methods for treating steatotic disease
|
|
EP2637698B1
(en)
|
2010-11-09 |
2022-04-20 |
Novo Nordisk A/S |
Double-acylated glp-1 derivatives
|
|
MX377589B
(es)
|
2010-12-16 |
2025-03-10 |
Novo Nordisk As |
Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico.
|
|
US20140004198A1
(en)
|
2011-01-19 |
2014-01-02 |
Novo Nordisk A/S |
Glp-1 particles and compositions
|
|
US20140045754A1
(en)
|
2011-01-19 |
2014-02-13 |
Joern Drustrup |
Glp-1 compositions
|
|
KR20140043709A
(ko)
|
2011-01-20 |
2014-04-10 |
질랜드 파마 에이/에스 |
아실화 글루카곤 유사체와 인슐린 유사체의 조합
|
|
WO2012104834A1
(en)
|
2011-02-03 |
2012-08-09 |
Pharmedica Ltd. |
New oral dissolving films for insulin administration, for treating diabetes
|
|
EP2683702B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8828995B2
(en)
|
2011-03-08 |
2014-09-09 |
Sanofi |
Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
WO2012120052A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683701B1
(de)
|
2011-03-08 |
2014-12-24 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683705B1
(de)
|
2011-03-08 |
2015-04-22 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683699B1
(de)
|
2011-03-08 |
2015-06-24 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8895547B2
(en)
|
2011-03-08 |
2014-11-25 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
|
US8871758B2
(en)
|
2011-03-08 |
2014-10-28 |
Sanofi |
Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
|
JP2014510739A
(ja)
|
2011-03-28 |
2014-05-01 |
ノヴォ ノルディスク アー/エス |
新規のグルカゴン類似体
|
|
WO2012150503A2
(en)
|
2011-05-03 |
2012-11-08 |
Zealand Pharma A/S |
Glu-glp-1 dual agonist signaling-selective compounds
|
|
WO2012153196A2
(en)
|
2011-05-10 |
2012-11-15 |
Zealand Pharma A/S |
Glu-glp-1 dual agonist signaling-selective compounds
|
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
|
WO2013006692A2
(en)
|
2011-07-06 |
2013-01-10 |
The General Hospital Corporation |
Methods of treatment using a pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1)
|
|
AR087693A1
(es)
|
2011-08-29 |
2014-04-09 |
Sanofi Aventis Deutschland |
Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
|
|
TWI559929B
(en)
|
2011-09-01 |
2016-12-01 |
Sanofi Aventis Deutschland |
Pharmaceutical composition for use in the treatment of a neurodegenerative disease
|
|
WO2013029279A1
(zh)
*
|
2011-09-03 |
2013-03-07 |
深圳市健元医药科技有限公司 |
新的glp-ⅰ类似物及其制备方法和用途
|
|
EP2753642B8
(en)
*
|
2011-09-06 |
2017-12-13 |
Novo Nordisk A/S |
Glp-1 derivatives
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
RU2610175C2
(ru)
|
2011-09-23 |
2017-02-08 |
Ново Нордиск А/С |
Новые аналоги глюкагона
|
|
TW201315742A
(zh)
|
2011-09-26 |
2013-04-16 |
Novartis Ag |
治療代謝病症之雙功能蛋白質
|
|
EP2760862B1
(en)
|
2011-09-27 |
2015-10-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
PL2763690T3
(pl)
|
2011-10-04 |
2016-04-29 |
Sanofi Aventis Deutschland |
Liksysenatyd do stosowania w leczeniu stenozy i/lub niedrożności w układzie przewodów trzustkowych
|
|
WO2013050378A1
(en)
|
2011-10-04 |
2013-04-11 |
Sanofi-Aventis Deutschland Gmbh |
Glp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
|
|
MX2014005351A
(es)
|
2011-11-03 |
2014-05-28 |
Zealand Pharma As |
Conjugados de gastrina peptidicos de agonistas de receptor glp-1.
|
|
WO2013083826A2
(en)
|
2011-12-09 |
2013-06-13 |
Novo Nordisk A/S |
Glp-1 agonists
|
|
JP6046161B2
(ja)
|
2011-12-29 |
2016-12-14 |
ノヴォ ノルディスク アー/エス |
非タンパク質新生アミノ酸を含むジペプチド
|
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
|
SMT201700488T1
(it)
|
2012-02-15 |
2017-11-15 |
Novo Nordisk As |
Anticorpi che legano e bloccano il recettore d'innesco espresso sulle cellule mieloidi-1 (trem-1)
|
|
JP6400480B2
(ja)
|
2012-02-15 |
2018-10-03 |
ノヴォ ノルディスク アー/エス |
ペプチドグリカン認識タンパク質1に結合する抗体
|
|
WO2013134519A2
(en)
|
2012-03-07 |
2013-09-12 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
EP3542790B1
(en)
|
2012-03-22 |
2023-09-13 |
Novo Nordisk A/S |
Compositions comprising a delivery agent and preparation thereof
|
|
CN104203266B
(zh)
|
2012-03-22 |
2017-12-26 |
诺和诺德股份有限公司 |
Glp‑1肽组合物及其制备
|
|
AU2013255752B2
(en)
|
2012-05-03 |
2017-11-09 |
Zealand Pharma A/S |
Glucagon-like-peptide-2 (GLP-2) analogues
|
|
JP6228187B2
(ja)
|
2012-05-03 |
2017-11-08 |
ジーランド ファーマ アクティーゼルスカブ |
Gip−glp−1デュアルアゴニスト化合物及び方法
|
|
ES2629735T3
(es)
*
|
2012-05-08 |
2017-08-14 |
Novo Nordisk A/S |
Derivados de GLP-1 doblemente acilados
|
|
JP6250034B2
(ja)
*
|
2012-05-08 |
2017-12-20 |
ノヴォ ノルディスク アー/エス |
二重アシル化されたglp−1誘導体
|
|
EP2664374A1
(en)
*
|
2012-05-15 |
2013-11-20 |
F. Hoffmann-La Roche AG |
Lysin-glutamic acid dipeptide derivatives
|
|
JP6517690B2
(ja)
|
2012-06-20 |
2019-05-22 |
ノヴォ ノルディスク アー/エス |
ペプチド及び送達剤を含む錠剤製剤
|
|
HRP20251088T1
(hr)
|
2012-07-01 |
2025-11-07 |
Novo Nordisk A/S |
Upotreba dugodjelujućih peptida glp‑1
|
|
EP2873422A4
(en)
|
2012-07-10 |
2015-12-30 |
Takeda Pharmaceutical |
PHARMACEUTICAL PREPARATION FOR INJECTION
|
|
AU2013295035B2
(en)
|
2012-07-23 |
2017-08-03 |
Zealand Pharma A/S |
Glucagon analogues
|
|
FR2994848B1
(fr)
|
2012-08-30 |
2014-08-22 |
Univ Paris Curie |
Traitement de l'arthrose par les hormones incretines ou leurs analogues
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
US20150273069A1
(en)
|
2012-10-17 |
2015-10-01 |
Novo Nordisk A/S |
Fatty acid acylated amino acids for oral peptide delivery
|
|
WO2014064215A1
(en)
|
2012-10-24 |
2014-05-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
|
|
WO2014093696A2
(en)
|
2012-12-12 |
2014-06-19 |
Massachusetts Institute Of Technology |
Insulin derivatives for diabetes treatment
|
|
HK1211232A1
(en)
|
2012-12-21 |
2016-05-20 |
Sanofi |
Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists
|
|
CN103059127B
(zh)
*
|
2013-01-07 |
2014-12-17 |
天津嘉宏科技有限公司 |
Glp-1类似物及其制备方法与应用
|
|
JP6368722B2
(ja)
|
2013-03-01 |
2018-08-01 |
フンダシオ オスピタル ウニベルシタリ バル デブロン−インスティテュート デ レセルカ |
網膜神経変性疾患の、特に、初期の糖尿病性網膜症及び神経変性が本質的な役割を果たす他の網膜疾患における局所治療における使用のためのペプチド
|
|
DK2968443T3
(da)
|
2013-03-15 |
2021-12-06 |
Protagonist Therapeutics Inc |
Hepcidinanaloger og anvendelser deraf
|
|
US11045523B2
(en)
|
2013-04-05 |
2021-06-29 |
Novo Nordisk Healthcare Ag |
Formulation of growth hormone albumin-binder conjugate
|
|
SI2986313T1
(sl)
|
2013-04-18 |
2019-09-30 |
Novo Nordisk A/S |
Stabilni koagonisti GLP-1 / glukagonskega receptorja z dolgotrajnim učinkom za medicinsko uporabo
|
|
JP6672140B2
(ja)
|
2013-05-02 |
2020-03-25 |
ノヴォ ノルディスク アー/エス |
Glp−1化合物の経口投薬
|
|
CA3130345A1
(en)
|
2013-07-03 |
2015-01-08 |
Deka Products Limited Partnership |
Apparatus, system and method for fluid delivery
|
|
US10266577B2
(en)
|
2013-08-15 |
2019-04-23 |
Novo Nordisk A/S |
GLP-1 derivatives, and uses thereof
|
|
GB201315335D0
(en)
|
2013-08-29 |
2013-10-09 |
Of Singapore |
Amino diacids containing peptide modifiers
|
|
WO2015055801A1
(en)
|
2013-10-17 |
2015-04-23 |
Zealand Pharma A/S |
Acylated glucagon analogues
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
CR20160207A
(es)
|
2013-11-05 |
2016-08-10 |
Ben Gurion Univ Of The Negev Res And Dev Authority |
Compuestos para el tratamiento de la diabetes y las complicaciones que surgen de la misma enfermedad
|
|
AU2014345570B2
(en)
|
2013-11-06 |
2019-01-24 |
Zealand Pharma A/S |
Glucagon-GLP-1-GIP triple agonist compounds
|
|
MX2016005556A
(es)
|
2013-11-06 |
2016-07-15 |
Zealand Pharma As |
Compuestos agonistas duales de gip-glp-1 y procedimientos.
|
|
TW201609799A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重glp-1/gip受體促效劑
|
|
WO2015086733A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/glucagon receptor agonists
|
|
EP3080152A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
WO2015086728A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
CN103884846B
(zh)
*
|
2014-03-06 |
2016-06-08 |
杭州九源基因工程有限公司 |
一种利拉鲁肽生物学活性的检测方法
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
US10689429B2
(en)
|
2014-04-07 |
2020-06-23 |
Novo Nordisk A/S |
Double-acylated GLP-1 compounds
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
PT3139948T
(pt)
*
|
2014-05-07 |
2020-05-22 |
Novo Nordisk As |
Tratamento de diabetes usando glp-1 e anti-il-21
|
|
SI3139948T1
(sl)
*
|
2014-05-07 |
2020-07-31 |
Novo Nordisk A/S |
Zdravljenje diabetesa tipa 1 z uporabo GLP-1 in anti-IL-21
|
|
PT3143037T
(pt)
|
2014-05-16 |
2021-09-24 |
Protagonist Therapeutics Inc |
Antagonistas peptídicos tioéter de integrina alfa4beta7
|
|
US10570184B2
(en)
|
2014-06-04 |
2020-02-25 |
Novo Nordisk A/S |
GLP-1/glucagon receptor co-agonists for medical use
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CN104987383A
(zh)
*
|
2014-07-08 |
2015-10-21 |
四川百利药业有限责任公司 |
一种glp-1衍生物
|
|
GB2528436A
(en)
|
2014-07-15 |
2016-01-27 |
Lancaster Univ Business Entpr Ltd |
Treatment of neurological diseases
|
|
US9624268B2
(en)
|
2014-07-17 |
2017-04-18 |
Protagonist Therapeutics, Inc. |
Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
|
|
EP3172232B1
(en)
|
2014-07-17 |
2023-12-27 |
Novo Nordisk A/S |
Site directed mutagenesis of trem-1 antibodies for decreasing viscosity.
|
|
US10968266B2
(en)
|
2014-09-05 |
2021-04-06 |
University Of Copenhagen |
GIP peptide analogues
|
|
KR20170108936A
(ko)
|
2014-10-01 |
2017-09-27 |
프로타고니스트 테라퓨틱스, 인코포레이티드 |
신규한 α4β7 펩타이드 단량체 및 이량체 길항제
|
|
EP3201217A4
(en)
|
2014-10-01 |
2018-07-18 |
Protagonist Therapeutics Inc. |
Novel cyclic monomer and dimer peptides having integrin antagonist activity
|
|
DK3006045T3
(en)
|
2014-10-07 |
2017-07-17 |
Cyprumed Gmbh |
Pharmaceutical formulations for oral administration of peptide or protein drugs
|
|
US10253078B2
(en)
|
2014-10-29 |
2019-04-09 |
Zealand Pharma A/S |
GIP agonist compounds and methods
|
|
JP6730278B2
(ja)
*
|
2014-11-27 |
2020-07-29 |
ノヴォ ノルディスク アー/エス |
Glp−1誘導体及びその使用
|
|
PE20171622A1
(es)
|
2014-12-12 |
2017-11-02 |
Sanofi Aventis Deutschland |
Formulacion de relacion fija de insulina glargina/lixisenatida
|
|
AR103246A1
(es)
|
2014-12-23 |
2017-04-26 |
Novo Nordiks As |
Derivados de fgf21 y sus usos
|
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
|
AR103954A1
(es)
|
2015-03-18 |
2017-06-14 |
Zealand Pharma As |
Análogos de amilina
|
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
|
US10426818B2
(en)
|
2015-03-24 |
2019-10-01 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Method and pharmaceutical composition for use in the treatment of diabetes
|
|
AR105319A1
(es)
|
2015-06-05 |
2017-09-27 |
Sanofi Sa |
Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|
|
US10787490B2
(en)
|
2015-07-15 |
2020-09-29 |
Protaganist Therapeutics, Inc. |
Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
|
|
EP3359181A1
(en)
|
2015-10-07 |
2018-08-15 |
Cyprumed GmbH |
Pharmaceutical formulations for the oral delivery of peptide drugs
|
|
US20190002503A1
(en)
|
2015-12-30 |
2019-01-03 |
Protagonist Therapeutics, Inc. |
Analogues of hepcidin mimetics with improved in vivo half lives
|
|
EP3196206A1
(en)
|
2016-01-20 |
2017-07-26 |
Lonza Ltd |
Method for preparation of liraglutide
|
|
EP3405476B1
(en)
|
2016-01-20 |
2022-05-18 |
Polypeptide Laboratories Holding (PPL) AB |
METHOD FOR PREPARATION OF PEPTIDES WITH psWANG LINKER
|
|
EP3205660A1
(en)
|
2016-02-10 |
2017-08-16 |
Polypeptide Laboratories Holding (PPL) AB |
Method for preparation of peptides with pswang linker
|
|
EP3205664A1
(en)
|
2016-02-11 |
2017-08-16 |
Polypeptide Laboratories Holding (PPL) AB |
Method for preparation of liraglutide using bal linker
|
|
WO2017149070A1
(en)
|
2016-03-03 |
2017-09-08 |
Novo Nordisk A/S |
Glp-1 derivatives and uses thereof
|
|
WO2017149109A1
(en)
|
2016-03-04 |
2017-09-08 |
Novo Nordisk A/S |
Liraglutide in diabetic foot ulcer
|
|
MA43684A
(fr)
|
2016-03-04 |
2018-11-28 |
Novo Nordisk As |
Liraglutide utilisé dans le traitement de maladies rénales
|
|
JP7011643B2
(ja)
|
2016-03-23 |
2022-02-10 |
バッヘン・ホールディング・アクチエンゲゼルシャフト |
グルカゴン様ペプチド1類似体の精製
|
|
WO2017165676A1
(en)
|
2016-03-23 |
2017-09-28 |
Protagonist Therapeutics, Inc. |
METHODS FOR SYNTHESIZING α4β7 PEPTIDE ANTAGONISTS
|
|
US11117946B2
(en)
|
2016-03-23 |
2021-09-14 |
Bachem Holding Ag |
Method for preparing glucagon-like peptides
|
|
TWI784968B
(zh)
|
2016-09-09 |
2022-12-01 |
丹麥商西蘭製藥公司 |
澱粉素類似物
|
|
EP3515408A1
(en)
|
2016-09-23 |
2019-07-31 |
Delpor, Inc. |
Stable compositions for incretin mimetic compounds
|
|
WO2018065634A1
(en)
|
2016-10-07 |
2018-04-12 |
Cyprumed Gmbh |
Pharmaceutical compositions for the nasal delivery of peptide or protein drugs
|
|
WO2018096164A1
(en)
|
2016-11-28 |
2018-05-31 |
Novo Nordisk A/S |
Insulin degludec for treating diabetes
|
|
WO2018096162A1
(en)
|
2016-11-28 |
2018-05-31 |
Novo Nordisk A/S |
Insulin degludec in cardiovascular conditions
|
|
MA46890A
(fr)
|
2016-11-28 |
2021-04-28 |
Novo Nordisk As |
Insuline degludec pour l'amélioration du contrôle glycémique et la réduction des complications du diabète aigu et à long terme
|
|
US11285180B2
(en)
|
2016-12-06 |
2022-03-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
|
|
JP2020500890A
(ja)
|
2016-12-09 |
2020-01-16 |
ジーランド・ファーマ・ア/エス |
Glp−1/glp−2二重アゴニスト
|
|
WO2018104558A1
(en)
|
2016-12-09 |
2018-06-14 |
Zealand Pharma A/S |
Acylated glp-1/glp-2 dual agonists
|
|
WO2018103868A1
(en)
|
2016-12-09 |
2018-06-14 |
Zealand Pharma A/S |
Acylated glp-1/glp-2 dual agonists
|
|
AU2017371516C1
(en)
|
2016-12-09 |
2021-09-02 |
Zealand Pharma A/S |
Acylated GLP-1/GLP-2 dual agonists
|
|
GB201621987D0
(en)
|
2016-12-22 |
2017-02-08 |
Archer Virgil L See Archer Sheri A Arecor Ltd |
Novel composition
|
|
JP2020514365A
(ja)
|
2017-03-15 |
2020-05-21 |
ノヴォ ノルディスク アー/エス |
メラノコルチン4受容体に結合可能な二環式化合物
|
|
WO2018210919A1
(en)
|
2017-05-17 |
2018-11-22 |
Novo Nordisk A/S |
Glp-1 compositions and uses thereof
|
|
PL3630806T3
(pl)
|
2017-05-31 |
2024-05-13 |
The University Of Copenhagen |
Analogi peptydów gip o długotrwałym działaniu
|
|
HRP20240485T1
(hr)
|
2017-08-24 |
2024-07-05 |
Novo Nordisk A/S |
Pripravci glp-1 i njihova upotreba
|
|
CN111163795A
(zh)
|
2017-09-10 |
2020-05-15 |
诺沃挪第克公司 |
用于治疗肥胖症的mic-1和glp-1
|
|
EP3681900A4
(en)
|
2017-09-11 |
2021-09-08 |
Protagonist Therapeutics, Inc. |
OPIOID AGONIST PEPTIDES AND THEIR USES
|
|
EP3728303A1
(en)
|
2017-12-19 |
2020-10-28 |
Novo Nordisk A/S |
Solubility of glp-1 peptide
|
|
PL3746111T3
(pl)
|
2018-02-02 |
2024-01-15 |
Novo Nordisk A/S |
Stałe kompozycje zawierające agonistę glp-1 i sól kwasu n-(8-(2- hydroksybenzoilo)amino kaprylowego i substancję poślizgową
|
|
EP3749345A4
(en)
|
2018-02-08 |
2022-04-06 |
Protagonist Therapeutics, Inc. |
CONJUGATED HEPCIDIN MIMETICS
|
|
PE20201254A1
(es)
|
2018-02-27 |
2020-11-16 |
Zp Spv 3 K/S |
Analogos de compstatina y sus usos medicos
|
|
EP3774902A1
(en)
|
2018-04-02 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
|
RS63523B1
(sr)
|
2018-04-05 |
2022-09-30 |
Sun Pharmaceutical Ind Ltd |
Novi glp-1 analozi
|
|
EP3773475A1
(en)
|
2018-04-06 |
2021-02-17 |
Cyprumed GmbH |
Pharmaceutical compositions for the transmucosal delivery of therapeutic peptides and proteins
|
|
WO2019200594A1
(zh)
|
2018-04-19 |
2019-10-24 |
杭州先为达生物科技有限公司 |
酰化的glp-1衍生物
|
|
WO2019209963A1
(en)
|
2018-04-24 |
2019-10-31 |
Deka Products Limited Partnership |
Apparatus and system for fluid delivery
|
|
TWI829687B
(zh)
|
2018-05-07 |
2024-01-21 |
丹麥商諾佛 儂迪克股份有限公司 |
包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
|
|
WO2019219714A1
(en)
|
2018-05-15 |
2019-11-21 |
Novo Nordisk A/S |
Compounds capable of binding to melanocortin 4 receptor
|
|
TW201946930A
(zh)
*
|
2018-05-15 |
2019-12-16 |
展旺生命科技股份有限公司 |
製備利拉魯肽衍生物的方法
|
|
US10905738B2
(en)
|
2018-07-05 |
2021-02-02 |
Biozeus Desenvolvimento De Produtos Biofarmacêuticos |
Synthetic peptides, prodrugs, pharmaceutical compositions and uses
|
|
TW202019948A
(zh)
|
2018-07-12 |
2020-06-01 |
美商領導醫療有限公司 |
介白素-23受體之肽抑制劑及其治療發炎疾病之用途
|
|
KR102919209B1
(ko)
|
2018-08-10 |
2026-01-28 |
다이아핀 테라퓨틱스, 엘엘씨 |
트리-펩타이드 그리고 대사, 심장혈관 및 염증성 장애의 치료
|
|
WO2020053414A1
(en)
|
2018-09-14 |
2020-03-19 |
Novo Nordisk A/S |
Bicyclic compounds capable of acting as melanocortin 4 receptor agonists
|
|
CN121449721A
(zh)
|
2018-12-03 |
2026-02-03 |
安泰博医药 |
经修饰的gip肽类似物
|
|
US20220315632A1
(en)
|
2019-03-15 |
2022-10-06 |
Diet4Life Aps |
Combination of dietary peptides
|
|
CN120518763A
(zh)
|
2019-04-01 |
2025-08-22 |
诺和诺德股份有限公司 |
针对利拉鲁肽的抗体及其用途
|
|
BR112021020941A2
(pt)
|
2019-06-14 |
2021-12-21 |
Zealand Pharma As |
Composição farmacêutica parenteral isotônica, método para melhoria da estabilidade química da dita composição e uso de manitol
|
|
CN114341161A
(zh)
|
2019-07-10 |
2022-04-12 |
领导医疗有限公司 |
白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途
|
|
ES3049784T3
(en)
|
2019-08-27 |
2025-12-18 |
Zp Spv 3 K/S |
Compstatin analogues and their medical uses
|
|
US20210061872A1
(en)
|
2019-09-03 |
2021-03-04 |
Protagonist Therapeutics, Inc. |
Conjugated hepcidin mimetics
|
|
CA3154744A1
(en)
|
2019-11-06 |
2021-05-14 |
Sarah FRIEDRICH |
Glp-1 receptor agonists in dementia
|
|
CN114641276A
(zh)
|
2019-11-07 |
2022-06-17 |
诺和诺德股份有限公司 |
包含glp-1激动剂、sglt2抑制剂和n-(8-(2-羟基苯甲酰基)氨基)辛酸的盐的固体组合物
|
|
WO2021105393A1
(en)
|
2019-11-29 |
2021-06-03 |
Novo Nordisk A/S |
Processes for obtaining stable glp-1 compositions
|
|
CN111040022B
(zh)
|
2019-12-23 |
2021-12-14 |
万新医药科技(苏州)有限公司 |
针对胰高血糖素样肽-1受体、胰高血糖素受体、以及抑胃肽受体的三重激动剂
|
|
CN119529057A
(zh)
|
2019-12-30 |
2025-02-28 |
甘李药业股份有限公司 |
长效glp-1化合物
|
|
HRP20250769T1
(hr)
|
2020-01-15 |
2025-08-29 |
Janssen Biotech, Inc. |
Peptidni inhibitori receptora za interleukin-23 i njihova uporaba u liječenju upalnih bolesti
|
|
AU2021209086A1
(en)
|
2020-01-15 |
2022-08-04 |
Janssen Biotech, Inc. |
Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
|
|
PE20230819A1
(es)
|
2020-02-18 |
2023-05-19 |
Novo Nordisk As |
Composiciones y usos de glp-1
|
|
EP4126004A1
(en)
|
2020-03-30 |
2023-02-08 |
Zealand Pharma A/S |
Agonist combination
|
|
EP4126003A1
(en)
|
2020-03-30 |
2023-02-08 |
Zealand Pharma A/S |
Glp-1/glp-2 dual agonists
|
|
US11478533B2
(en)
|
2020-04-27 |
2022-10-25 |
Novo Nordisk A/S |
Semaglutide for use in medicine
|
|
EP4142695B1
(en)
|
2020-04-29 |
2025-11-05 |
Novo Nordisk A/S |
Solid compositions comprising a glp-1 agonist and histidine
|
|
EP4146221A1
(en)
|
2020-05-07 |
2023-03-15 |
Frederiksberg Hospital |
Treatment of hyperuricemia
|
|
WO2022049310A1
(en)
|
2020-09-07 |
2022-03-10 |
Cyprumed Gmbh |
Improved pharmaceutical formulations of glp-1 receptor agonists
|
|
CN114729060B
(zh)
*
|
2020-09-30 |
2022-11-25 |
北京质肽生物医药科技有限公司 |
多肽缀合物和使用方法
|
|
AU2021383828A1
(en)
|
2020-11-20 |
2023-07-06 |
Janssen Pharmaceutica Nv |
Compositions of peptide inhibitors of interleukin-23 receptor
|
|
US20250325469A1
(en)
|
2021-01-24 |
2025-10-23 |
Michael David FORREST |
Inhibitors of atp synthase - cosmetic and therapeutic uses
|
|
FR3120189B1
(fr)
|
2021-03-01 |
2024-11-29 |
Farid Bennis |
Composition pharmaceutique pour une administration par voie orale d’un agoniste du récepteur du GLP-1
|
|
CN113025675B
(zh)
*
|
2021-05-21 |
2021-08-20 |
凯莱英医药集团(天津)股份有限公司 |
多肽的制备方法
|
|
WO2023285334A1
(en)
|
2021-07-12 |
2023-01-19 |
Novo Nordisk A/S |
Novel fatty acid modified urocortin 2 derivatives and the uses thereof
|
|
CA3224743A1
(en)
|
2021-07-14 |
2023-01-19 |
Beijing Ql Biopharmaceutical Co., Ltd. |
Fusion polypeptides for metabolic disorders
|
|
WO2023288019A2
(en)
|
2021-07-14 |
2023-01-19 |
Janssen Biotech, Inc. |
Lipidated peptide inhibitors of interleukin-23 receptor
|
|
WO2023012263A1
(en)
|
2021-08-04 |
2023-02-09 |
Novo Nordisk A/S |
Solid oral peptide formulations
|
|
AU2022339044A1
(en)
|
2021-09-03 |
2024-03-14 |
Zealand Pharma A/S |
Dosage regime
|
|
WO2023038039A1
(ja)
|
2021-09-08 |
2023-03-16 |
塩野義製薬株式会社 |
抗肥満作用の関与する疾患の予防及び治療用医薬
|
|
WO2023192873A1
(en)
*
|
2022-03-28 |
2023-10-05 |
Bristol-Myers Squibb Company |
Macrocyclic immunomodulators
|
|
EP4323413A4
(en)
|
2022-03-30 |
2025-10-15 |
Beijing Ql Biopharmaceutical Co Ltd |
LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF
|
|
WO2024061919A1
(en)
|
2022-09-19 |
2024-03-28 |
Zealand Pharma A/S |
Combination therapy
|
|
WO2024068848A1
(en)
|
2022-09-28 |
2024-04-04 |
Zealand Pharma A/S |
Methods for treating obesity
|
|
EP4345104B1
(en)
|
2022-09-30 |
2024-08-28 |
Bachem Holding AG |
Method for preparing liraglutide
|
|
TW202421645A
(zh)
|
2022-11-25 |
2024-06-01 |
丹麥商諾佛 儂迪克股份有限公司 |
如glp—1之肽治療劑的口服投與
|
|
WO2024123812A1
(en)
|
2022-12-05 |
2024-06-13 |
Shattuck Labs, Inc. |
Fusion proteins for the treatment of cardiometabolic diseases
|
|
JP2026502943A
(ja)
|
2022-12-30 |
2026-01-27 |
アルギファルマ エーエス |
経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法
|
|
WO2024165571A2
(en)
|
2023-02-06 |
2024-08-15 |
E-Therapeutics Plc |
Inhibitors of expression and/or function
|
|
EP4724471A1
(en)
|
2023-06-09 |
2026-04-15 |
Sun Pharmaceutical Industries Limited |
Glp-1/gip dual, glp-1/gcg dual and glp-1/gip/gcg triple receptor agonists
|
|
EP4727524A1
(en)
|
2023-06-15 |
2026-04-22 |
Novo Nordisk A/S |
Pharmaceutical formulations of an amylin receptor agonist and a glp-1 receptor agonist comprising a cyclodextrin
|
|
CN121358489A
(zh)
|
2023-06-21 |
2026-01-16 |
西兰制药公司 |
具有改善特性的类似物
|
|
TW202504913A
(zh)
|
2023-06-21 |
2025-02-01 |
丹麥商西蘭製藥公司 |
減重
|
|
AU2024306538A1
(en)
|
2023-06-30 |
2025-12-04 |
Zealand Pharma A/S |
Combination therapy
|
|
WO2025069009A1
(en)
|
2023-09-29 |
2025-04-03 |
Graviton Bioscience Bv |
Rock2 inhibitors in the treatment of obesity
|
|
WO2025122721A1
(en)
*
|
2023-12-05 |
2025-06-12 |
Shattuck Labs, Inc. |
Chimeric proteins and uses thereof
|
|
WO2025125576A2
(en)
|
2023-12-15 |
2025-06-19 |
E-Therapeutics Plc |
Inhibitors of expression and/or function
|
|
WO2025133348A1
(en)
|
2023-12-22 |
2025-06-26 |
E-Therapeutics Plc |
Inhibitors of expression and/or function
|
|
EP4686757A1
(en)
|
2024-07-31 |
2026-02-04 |
e-therapeutics PLC |
Inhibitors of expression and/or function
|
|
WO2025196502A1
(en)
|
2024-03-20 |
2025-09-25 |
North Carolina Agricultural & Technical State University |
Choline kinase inhibitors as a therapeutic treatment for obesity
|
|
WO2026073030A1
(en)
|
2024-09-27 |
2026-04-02 |
Carmot Therapeutics Inc. |
Combination therapy of peptide tyrosine-tyrosine (pyy) analogues and glp-1r agonists
|
|
DK182293B1
(en)
|
2025-01-16 |
2026-02-25 |
Novo Nordisk As |
Semaglutide for use in medical therapy including weight management
|