MX2011007736A - Compuestos de hormona del crecimiento estables. - Google Patents

Compuestos de hormona del crecimiento estables.

Info

Publication number
MX2011007736A
MX2011007736A MX2011007736A MX2011007736A MX2011007736A MX 2011007736 A MX2011007736 A MX 2011007736A MX 2011007736 A MX2011007736 A MX 2011007736A MX 2011007736 A MX2011007736 A MX 2011007736A MX 2011007736 A MX2011007736 A MX 2011007736A
Authority
MX
Mexico
Prior art keywords
growth hormone
stable growth
hormone compounds
compounds
stable
Prior art date
Application number
MX2011007736A
Other languages
English (en)
Inventor
Ole Hvilsted Olsen
Peter Thygesen
Christine Bruun Schioedt
Leif Noerskov-Lauritsen
Jens Breinholt
Helle Demuth
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of MX2011007736A publication Critical patent/MX2011007736A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a compuestos de hormona del crecimiento (GH) estables, que a través de la introducción de residuos de cisteína tienen puentes de disulfuro, que hacen a los compuestos resistentes a la degradación proteolítica.
MX2011007736A 2009-01-22 2010-01-22 Compuestos de hormona del crecimiento estables. MX2011007736A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09151108 2009-01-22
US14811909P 2009-01-29 2009-01-29
PCT/EP2010/050725 WO2010084173A1 (en) 2009-01-22 2010-01-22 Stable growth hormone compounds

Publications (1)

Publication Number Publication Date
MX2011007736A true MX2011007736A (es) 2011-09-06

Family

ID=40521462

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007736A MX2011007736A (es) 2009-01-22 2010-01-22 Compuestos de hormona del crecimiento estables.

Country Status (14)

Country Link
US (1) US8513192B2 (es)
EP (1) EP2389389B1 (es)
JP (2) JP5816097B2 (es)
KR (1) KR20110122100A (es)
CN (1) CN102292349B (es)
AU (1) AU2010207725B2 (es)
CA (1) CA2747825A1 (es)
ES (1) ES2542202T3 (es)
IL (1) IL213686A0 (es)
MX (1) MX2011007736A (es)
RU (1) RU2539797C2 (es)
TW (1) TWI504405B (es)
WO (1) WO2010084173A1 (es)
ZA (1) ZA201105419B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0917000A2 (pt) 2008-08-06 2016-02-16 Novo Nordisk Healthcare Ag proteínas conjugadas com eficácia in vivo prolongada
EP2389389B1 (en) 2009-01-22 2015-04-15 Novo Nordisk Health Care AG Stable growth hormone compounds
US8841249B2 (en) 2009-08-06 2014-09-23 Novo Nordisk A/S Growth hormones with prolonged in-vivo efficacy
CA2787895A1 (en) 2010-01-22 2011-07-28 Novo Nordisk Health Care Ag Stable growth hormone compounds
MX345736B (es) 2010-01-22 2017-02-14 Novo Nordisk Healthcare Ag Hormonas de crecimiento con eficacia in vivo prolongada.
WO2012010516A1 (en) * 2010-07-22 2012-01-26 Novo Nordisk Health Care Ag Growth hormone conjugates
JP6464145B2 (ja) 2013-04-05 2019-02-06 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 成長ホルモン化合物製剤

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Also Published As

Publication number Publication date
AU2010207725A1 (en) 2011-07-21
EP2389389B1 (en) 2015-04-15
EP2389389A1 (en) 2011-11-30
US8513192B2 (en) 2013-08-20
TWI504405B (zh) 2015-10-21
AU2010207725B2 (en) 2015-06-11
ZA201105419B (en) 2012-04-25
RU2539797C2 (ru) 2015-01-27
JP5816097B2 (ja) 2015-11-18
TW201032819A (en) 2010-09-16
IL213686A0 (en) 2011-07-31
CA2747825A1 (en) 2010-07-29
KR20110122100A (ko) 2011-11-09
RU2011133926A (ru) 2013-02-27
WO2010084173A1 (en) 2010-07-29
CN102292349A (zh) 2011-12-21
CN102292349B (zh) 2016-04-13
JP2015193636A (ja) 2015-11-05
US20110306548A1 (en) 2011-12-15
ES2542202T3 (es) 2015-08-03
JP2012515748A (ja) 2012-07-12

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