MX339402B - Composiciones y metodos que comprenden variantes de serina proteasa. - Google Patents

Composiciones y metodos que comprenden variantes de serina proteasa.

Info

Publication number
MX339402B
MX339402B MX2011004818A MX2011004818A MX339402B MX 339402 B MX339402 B MX 339402B MX 2011004818 A MX2011004818 A MX 2011004818A MX 2011004818 A MX2011004818 A MX 2011004818A MX 339402 B MX339402 B MX 339402B
Authority
MX
Mexico
Prior art keywords
serine protease
protease variants
compositions
methods
present
Prior art date
Application number
MX2011004818A
Other languages
English (en)
Other versions
MX2011004818A (es
Inventor
David A Estell
James T Kellis Jr
Ayrookaran J Poulose
Frits Goedegebuur
Wolfgang Aehle
Luis G Cascao-Pereira
Brian F Schmidt
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of MX2011004818A publication Critical patent/MX2011004818A/es
Publication of MX339402B publication Critical patent/MX339402B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609—Protease or amylase in solid compositions only
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618—Protease or amylase in liquid compositions only
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38654—Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a métodos para fabricación por ingeniería de proteína y variantes de serina proteasa producidos de ellos. Específicamente, la presente invención proporciona variantes de serina proteasa que tienen una o más sustituciones como se compara con una serina proteasa de referencia. Además, la presente invención proporciona composiciones que comprenden estas variantes de serina proteasa. En algunas modalidades, la presente invención proporciona composiciones de limpieza que comprenden al menos una de estas variantes de serina proteasa.
MX2011004818A 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa. MX339402B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11354808P 2008-11-11 2008-11-11
US11355208P 2008-11-11 2008-11-11
US11354508P 2008-11-11 2008-11-11
US21880209P 2009-06-19 2009-06-19
PCT/US2009/063808 WO2010056640A2 (en) 2008-11-11 2009-11-10 Compositions and methods comprising serine protease variants

Publications (2)

Publication Number Publication Date
MX2011004818A MX2011004818A (es) 2011-05-31
MX339402B true MX339402B (es) 2016-05-25

Family

ID=42025792

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011004818A MX339402B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.
MX2015014217A MX383346B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2015014217A MX383346B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.

Country Status (11)

Country Link
US (4) US20100192985A1 (es)
EP (3) EP2362897A2 (es)
JP (4) JP5727378B2 (es)
KR (1) KR20110091671A (es)
CN (3) CN103396904B (es)
AR (1) AR073420A1 (es)
BR (2) BRPI0922084B1 (es)
CA (1) CA2743047A1 (es)
MX (2) MX339402B (es)
RU (1) RU2011123911A (es)
WO (1) WO2010056640A2 (es)

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2367505T3 (es) * 1997-10-23 2011-11-04 Danisco Us Inc. Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes.
CA2472725C (en) * 2002-01-16 2015-08-11 Genencor International, Inc. Multiply-substituted protease variants
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
CN104694519B (zh) 2008-06-06 2023-10-27 丹尼斯科美国公司 包含微生物蛋白酶变体的组合物和方法
MX339402B (es) * 2008-11-11 2016-05-25 Danisco Us Inc Composiciones y metodos que comprenden variantes de serina proteasa.
EP4159833A3 (en) 2009-12-09 2023-07-26 The Procter & Gamble Company Fabric and home care products
US20110281327A1 (en) * 2010-04-15 2011-11-17 Danisco Us Inc. Compositions And Methods Comprising Variant Proteases
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
CN108410585A (zh) * 2010-05-06 2018-08-17 宝洁公司 具有蛋白酶变体的消费品
DE102010063458A1 (de) * 2010-12-17 2012-06-21 Henkel Ag & Co. Kgaa Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Amylase
BR112013028440A2 (pt) * 2011-05-05 2016-11-29 Procter & Gamble composições e métodos que compreendem variantes de serina protease
JP5933688B2 (ja) * 2011-05-05 2016-06-15 ザ プロクター アンド ギャンブル カンパニー セリンプロテアーゼ変異体を含む組成物及び方法
CN103764823B (zh) * 2011-05-05 2018-05-11 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
US10093911B2 (en) * 2012-02-17 2018-10-09 Novozymes A/S Subtilisin variants and polynucleotides encoding same
JP6282270B2 (ja) 2012-07-09 2018-02-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 組み換えにより生成されたパエニバシラス・ポリミキサに由来する中性プロテアーゼ
JP6294228B2 (ja) * 2012-09-14 2018-03-14 天野エンザイム株式会社 糖質酸化酵素とその製造方法並びに用途
EP3354728B1 (en) 2012-12-21 2020-04-22 Danisco US Inc. Alpha-amylase variants
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
CN110777132B (zh) 2013-03-11 2024-03-22 丹尼斯科美国公司 α-淀粉酶组合变体
EP4159854A1 (en) 2013-05-29 2023-04-05 Danisco US Inc Novel metalloproteases
WO2014194117A2 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
WO2014194054A1 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
RU2016102045A (ru) 2013-06-27 2017-08-01 Новозимс А/С Варианты субтилаз и кодирующие их полинуклеотиды
US10647974B2 (en) * 2013-06-27 2020-05-12 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2015057619A1 (en) 2013-10-15 2015-04-23 Danisco Us Inc. Clay granule
EP3068879B1 (en) 2013-11-14 2019-12-25 Danisco US Inc. Stable enzymes by glycation reduction
WO2015089447A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of the bacillus gibsonii-clade
EP3514230B1 (en) 2013-12-13 2021-09-22 Danisco US Inc. Serine proteases of bacillus species
AU2014366222B2 (en) 2013-12-16 2018-07-19 Nutrition & Biosciences USA 4, Inc. Use of poly alpha-1,3-glucan ethers as viscosity modifiers
JP6559139B2 (ja) 2013-12-18 2019-08-14 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ カチオン性ポリα−１，３−グルカンエーテル
EP3097172A1 (en) 2014-01-22 2016-11-30 The Procter & Gamble Company Method of treating textile fabrics
WO2015112339A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Fabric treatment composition
WO2015112340A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Method of treating textile fabrics
EP3097175B1 (en) 2014-01-22 2018-10-17 The Procter and Gamble Company Fabric treatment composition
US20150232785A1 (en) 2014-02-14 2015-08-20 E I Du Pont De Nemours And Company Polysaccharides for viscosity modification
ES2734726T3 (es) 2014-03-11 2019-12-11 Du Pont Poli alfa-1,2-glucano oxidado como reforzante de detergente
JP6585698B2 (ja) 2014-03-21 2019-10-02 ダニスコ・ユーエス・インク バチルス（Ｂａｃｉｌｌｕｓ）種のセリンプロテアーゼ
US20170204352A1 (en) * 2014-04-01 2017-07-20 Novozymes A/S Detergent Composition
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3158043B1 (en) 2014-06-19 2021-03-10 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US10626388B2 (en) 2014-07-04 2020-04-21 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3878960A1 (en) 2014-07-04 2021-09-15 Novozymes A/S Subtilase variants and polynucleotides encoding same
GB201414130D0 (en) * 2014-08-08 2014-09-24 Agency Science Tech & Res Mutants of the bacteriophage lambda integrase
WO2016036209A1 (ko) * 2014-09-05 2016-03-10 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 향상된 미생물 및 이를 이용한 l-쓰레오닌 생산방법
HUE050610T2 (hu) * 2014-09-05 2021-01-28 Cj Cheiljedang Corp Javított L-treonin termelésére képes mikroorganizmus, és eljárás L-treonin elõállítására annak alkalmazásával
US10138268B2 (en) 2014-10-10 2018-11-27 Enzypep B.V. Peptide fragment condensation and cyclisation using a subtilisin variant with improved synthesis over hydrolysis ratio
EP3207129B1 (en) 2014-10-17 2019-11-20 Danisco US Inc. Serine proteases of bacillus species
BR112017007949A2 (pt) 2014-10-24 2018-01-23 Danisco Us Inc método para produção de álcool pelo uso de uma tripeptidil-peptidase
EP3957729A1 (en) 2014-10-27 2022-02-23 Danisco US Inc. Serine proteases
WO2016069552A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
EP3212781B1 (en) 2014-10-27 2019-09-18 Danisco US Inc. Serine proteases
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
US20180010074A1 (en) * 2014-10-27 2018-01-11 Danisco Us Inc. Serine proteases of bacillus species
AT516457B1 (de) * 2014-11-07 2017-03-15 Erber Ag Polypeptid zur enzymatischen Detoxifizierung von Zearalenon, sowie isoliertes Polynukleotid, sowie Zusatzstoff, Verwendung und Verfahren desselben
MX2017006377A (es) 2014-11-17 2017-08-21 Procter & Gamble Composiciones de suministro de agentes beneficos.
CN116286218A (zh) * 2014-12-04 2023-06-23 诺维信公司 包括蛋白酶变体的液体清洁组合物
EP3690037A1 (en) 2014-12-04 2020-08-05 Novozymes A/S Subtilase variants and polynucleotides encoding same
DK3399031T3 (da) * 2014-12-15 2020-01-20 Henkel Ag & Co Kgaa Detergentsammensætning med subtilasevarianter
JP2018512109A (ja) 2014-12-23 2018-05-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 酵素により製造されるセルロース
US20180216090A1 (en) * 2015-03-12 2018-08-02 Danisco Us Inc. Compositions and methods comprising lg12-clade protease variants
DK3088505T3 (da) 2015-04-29 2020-08-03 Procter & Gamble Fremgangsmåde til behandling af et tekstilstof
US20160319227A1 (en) 2015-04-29 2016-11-03 The Procter & Gamble Company Method of treating a fabric
CN107532116B (zh) 2015-04-29 2021-05-07 宝洁公司 处理织物的方法
WO2016176280A1 (en) 2015-04-29 2016-11-03 The Procter & Gamble Company Method of treating a fabric
JP2018521149A (ja) 2015-04-29 2018-08-02 ザ プロクター アンド ギャンブル カンパニー 洗剤組成物
EP3294884B1 (en) * 2015-05-13 2021-01-27 Danisco US Inc. Aprl-clade protease variants and uses thereof
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
EP4234693A3 (en) 2015-06-17 2023-11-01 Danisco US Inc Bacillus gibsonii-clade serine proteases
WO2017079751A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus sp. mannanases
WO2017079756A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus and bacillus spp. mannanases
CN108350438B (zh) * 2015-11-06 2022-06-24 天野酶株式会社 新型葡萄糖脱氢酶
JP7045313B2 (ja) 2015-11-13 2022-03-31 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
WO2017083229A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
WO2017089093A1 (en) 2015-11-25 2017-06-01 Unilever N.V. A liquid detergent composition
EP3387124B1 (en) 2015-12-09 2021-05-19 Danisco US Inc. Alpha-amylase combinatorial variants
US20180362946A1 (en) 2015-12-18 2018-12-20 Danisco Us Inc. Polypeptides with endoglucanase activity and uses thereof
CN108779449A (zh) 2016-02-06 2018-11-09 诺维信公司 具有蛋白酶活性的多肽以及编码其的多核苷酸
EP4095152A3 (en) 2016-03-04 2022-12-28 Danisco US Inc. Engineered ribosomal promoters for protein production in microorganisms
CA3022875A1 (en) * 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
US11661567B2 (en) 2016-05-31 2023-05-30 Danisco Us Inc. Protease variants and uses thereof
CN110129300B (zh) * 2016-06-02 2021-08-03 天津科技大学 一种磷脂酶d
MX2018015559A (es) 2016-06-17 2019-06-06 Danisco Us Inc Variantes de proteasa y sus usos.
EP3275988B1 (en) * 2016-07-26 2020-07-08 The Procter and Gamble Company Automatic dishwashing detergent composition
JP6970101B2 (ja) * 2016-09-15 2021-11-24 花王株式会社 変異糸状菌、及びそれを用いたｃ４ジカルボン酸の製造方法
WO2018062178A1 (ja) * 2016-09-28 2018-04-05 国立研究開発法人理化学研究所 ジホスホメバロン酸デカルボキシラーゼ変異体、及びそれを用いたオレフィン化合物の製造方法
WO2018078014A1 (en) 2016-10-27 2018-05-03 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
CN106566818B (zh) * 2016-10-28 2019-05-17 中国农业科学院饲料研究所 酸性嗜热多聚半乳糖醛酸酶TePG28A及其编码基因和应用
EP3535365A2 (en) 2016-11-07 2019-09-11 Danisco US Inc. Laundry detergent composition
MX2019006422A (es) 2016-12-02 2019-08-01 Procter & Gamble Composiciones de limpieza que incluyen enzimas.
US10550443B2 (en) 2016-12-02 2020-02-04 The Procter & Gamble Company Cleaning compositions including enzymes
WO2018102478A1 (en) 2016-12-02 2018-06-07 The Procter & Gamble Company Cleaning compositions including enzymes
EP4424805A3 (en) 2016-12-21 2024-11-20 Danisco Us Inc Bacillus gibsonii-clade serine proteases
US20200392477A1 (en) 2016-12-21 2020-12-17 Danisco Us Inc. Protease variants and uses thereof
US11155793B2 (en) * 2017-01-15 2021-10-26 Feed Research Institute Chinese Academy Of Agricul Phytase variants YeAPPA having improved gastric protein resistance and acid resistance, and increased catalytic efficiency
JP7054092B2 (ja) * 2017-02-01 2022-04-13 国立研究開発法人理化学研究所 ジホスホメバロン酸デカルボキシラーゼ変異体、及びそれを用いたオレフィン化合物の製造方法
US11051520B2 (en) * 2017-02-20 2021-07-06 Novozymes A/S Lipolytic enzyme for use in baking
WO2018169750A1 (en) 2017-03-15 2018-09-20 Danisco Us Inc Trypsin-like serine proteases and uses thereof
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
CN110494553B (zh) * 2017-04-13 2023-07-04 协和发酵生化株式会社 茶氨酸的制造方法
ES2949068T3 (es) * 2017-05-03 2023-09-25 Firmenich & Cie Sesquiterpeno sintasas para la producción de drimenol y mezclas de los mismos
JP7680825B2 (ja) 2017-06-30 2025-05-21 ダニスコ・ユーエス・インク 低凝集の酵素含有粒子
AU2018334514B2 (en) * 2017-09-13 2025-01-30 Nutrition & Biosciences USA 4, Inc. Engineered glucosyltransferases
WO2019089898A1 (en) 2017-11-02 2019-05-09 Danisco Us Inc Freezing point depressed solid matrix compositions for melt granulation of enzymes
WO2019108599A1 (en) 2017-11-29 2019-06-06 Danisco Us Inc Subtilisin variants having improved stability
EP3502245B1 (en) * 2017-12-19 2025-03-05 The Procter & Gamble Company Automatic dishwashing detergent composition
CN111742041B (zh) 2017-12-21 2023-06-06 丹尼斯科美国公司 包含耐热干燥剂的含酶的热熔细粒
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
JP7124338B2 (ja) * 2018-02-27 2022-08-24 味の素株式会社 変異型グルタチオン合成酵素、及び、γ－グルタミルバリルグリシンの製造法
WO2019195842A1 (en) * 2018-04-06 2019-10-10 Braskem S.A. Novel nadh-dependent enzyme mutants to convert acetone into isopropanol
US11034980B2 (en) * 2018-05-29 2021-06-15 Massachusetts Institute Of Technology Microbial engineering for the production of isoprenoids
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
EP3799601A1 (en) 2018-06-19 2021-04-07 Danisco US Inc. Subtilisin variants
EP3599282B1 (en) * 2018-07-24 2021-03-17 Evonik Operations GmbH Method for the fermentative production of l-lysine
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
WO2020068486A1 (en) 2018-09-27 2020-04-02 Danisco Us Inc Compositions for medical instrument cleaning
JP7078900B2 (ja) * 2018-10-05 2022-06-01 トヨタ自動車株式会社 形質転換酵母及びこれを用いたエタノールの製造方法
US12509672B2 (en) * 2018-11-28 2025-12-30 Danisco Us Inc. Subtilisin variants having improved stability
CN109481336B (zh) * 2018-12-19 2021-10-26 广州立白企业集团有限公司 口腔护理组合物及其应用
CN109456957B (zh) * 2018-12-19 2021-01-01 广州立白企业集团有限公司 蛋白酶变体、液体洗涤剂组合物及其应用
US10829746B2 (en) * 2019-01-23 2020-11-10 Evonik Operations Gmbh Method for the fermentative production of L-lysine
CN114174504A (zh) 2019-05-24 2022-03-11 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP3976775A1 (en) 2019-05-24 2022-04-06 The Procter & Gamble Company Automatic dishwashing detergent composition
CN114174486A (zh) 2019-06-06 2022-03-11 丹尼斯科美国公司 用于清洁的方法和组合物
US11492571B2 (en) 2019-10-24 2022-11-08 The Procter & Gamble Company Automatic dishwashing detergent composition comprising a protease
KR102316445B1 (ko) * 2019-11-29 2021-10-26 씨제이제일제당 주식회사 신규 세린 프로테아제 변이체
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
EP4204554A4 (en) * 2020-08-28 2024-08-21 Codexis, Inc. MODIFIED PROTEASE VARIANTS
EP4204547A1 (en) * 2020-08-28 2023-07-05 Novozymes A/S Protease variants with improved solubility
EP4284906A1 (en) 2021-01-29 2023-12-06 Danisco US Inc. Compositions for cleaning and methods related thereto
WO2022171667A1 (en) * 2021-02-12 2022-08-18 Fresenius Kabi Ipsum S.R.L. Subtilisin variants and their use
CN112725316B (zh) * 2021-03-04 2022-09-06 宁夏夏盛实业集团有限公司 碱性蛋白酶2018突变体及其制备方法
KR102613549B1 (ko) 2021-03-12 2023-12-13 씨제이제일제당 주식회사 신규 세린 프로테아제 변이체
US20240294888A1 (en) 2021-06-30 2024-09-05 Danisco Us Inc. Variant enzymes and uses thereof
EP4396320A2 (en) 2021-09-03 2024-07-10 Danisco US Inc. Laundry compositions for cleaning
CN117957318A (zh) 2021-09-13 2024-04-30 丹尼斯科美国公司 含有生物活性物质的颗粒
CN118679252A (zh) 2021-12-16 2024-09-20 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
US20250051748A1 (en) 2021-12-16 2025-02-13 Danisco Us Inc. Subtilisin variants and methods of use
EP4448750A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and uses thereof
CN118974227A (zh) 2022-03-01 2024-11-15 丹尼斯科美国公司 用于清洁的酶和酶组合物
US12416044B2 (en) * 2022-03-21 2025-09-16 Abclonal Science, Inc. T4 DNA ligase variants with increased ligation efficiency
CA3257053A1 (en) 2022-05-14 2023-11-23 Novozymes A/S COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS
CN119487167A (zh) 2022-06-21 2025-02-18 丹尼斯科美国公司 用于清洁的包含具有嗜热菌蛋白酶活性的多肽的组合物和方法
DE102022208891A1 (de) 2022-08-16 2024-02-22 Henkel Ag & Co. Kgaa Leistungsverbesserte protease-varianten x
DE102022208890A1 (de) 2022-08-16 2024-02-22 Henkel Ag & Co. Kgaa Leistungsverbesserte protease-varianten ix
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
EP4581138A1 (en) 2022-09-02 2025-07-09 Danisco US Inc. Subtilisin variants and methods related thereto
CA3265943A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. DETERGENT COMPOSITIONS AND ASSOCIATED PROCESSES
CN120693402A (zh) 2022-11-04 2025-09-23 巴斯夫欧洲公司 用于在洗涤剂组合物中使用的具有蛋白酶活性的多肽
WO2024094735A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2024094733A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4615968A1 (en) * 2022-11-09 2025-09-17 Danisco US Inc. Subtilisin variants and methods of use
EP4658776A1 (en) 2023-02-01 2025-12-10 Danisco US Inc. Subtilisin variants and methods of use
CN116064490B (zh) * 2023-03-05 2025-12-12 中国农业科学院北京畜牧兽医研究所 一种提高碱性蛋白酶热稳定性的方法及突变体ThAPT3-M3、ThAPT3-M4和应用
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP4680013A1 (en) 2023-03-16 2026-01-21 Nutrition & Biosciences USA 4, Inc. Brevibacillus fermentate extracts for cleaning and malodor control and use thereof
CN116676296A (zh) * 2023-06-08 2023-09-01 江南大学 酶活提高的β-1,3-葡聚糖酶突变体
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
CN117535273B (zh) * 2023-11-07 2024-06-07 南京诺唯赞生物科技股份有限公司 温敏型碱性蛋白酶变体及其应用
WO2025202372A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4624572A1 (en) 2024-03-27 2025-10-01 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202379A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202369A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202382A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in cleaning compositions
WO2025202374A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2026024921A1 (en) 2024-07-25 2026-01-29 The Procter & Gamble Company Detergent composition comprising a subtilisin variant and methods of use
DE102024207057A1 (de) 2024-07-26 2026-01-29 Henkel Ag & Co. Kgaa Protease-varianten mit verbesserter lagerstabilität
WO2026050315A1 (en) 2024-08-29 2026-03-05 Danisco Us Inc. Subtilisin variants and methods of use
CN119530204B (zh) * 2024-12-09 2025-11-04 湖北大学 水解胶原蛋白的酶及应用

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (es) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB2048606B (en) 1979-02-28 1983-03-16 Barr & Stroud Ltd Optical scanning system
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
GR76237B (es) * 1981-08-08 1984-08-04 Procter & Gamble
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5801038A (en) * 1984-05-29 1998-09-01 Genencor International Inc. Modified subtilisins having amino acid alterations
US5972682A (en) 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK171161B1 (da) 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
US5024943A (en) 1985-11-07 1991-06-18 Gist-Brocades Regulatory region cloning and analysis plasmid for bacillus
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US4810414A (en) 1986-08-29 1989-03-07 Novo Industri A/S Enzymatic detergent additive
GB8629837D0 (en) 1986-12-13 1987-01-21 Interox Chemicals Ltd Bleach activation
EP0322429B1 (en) 1987-05-29 1994-10-19 Genencor International, Inc. Cutinase cleaning composition
EP0305216B1 (en) 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
JPH0633189Y2 (ja) 1987-09-14 1994-08-31 立山アルミニウム工業株式会社 サッシ枠の連結装置
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
DE68923398T2 (de) 1988-05-12 1996-01-25 Procter & Gamble Flüssige Universalwaschmittel, welche anionische und nichtionische oberflächenaktive Mittel, Gerüststoffe und proteolytisches Enzym enthalten.
US4883195A (en) * 1988-11-02 1989-11-28 Restaurant Technology, Inc. Pizza container
WO1990009446A1 (en) 1989-02-17 1990-08-23 Plant Genetic Systems N.V. Cutinase
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
DE59101948D1 (de) 1990-04-14 1994-07-21 Kali Chemie Ag Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren.
US5354559A (en) * 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
ES2174820T3 (es) 1991-01-16 2002-11-16 Procter & Gamble Composiciones detergentes compactas con celulasa de alta actividad.
GB9108136D0 (en) 1991-04-17 1991-06-05 Unilever Plc Concentrated detergent powder compositions
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
BR9307576A (pt) 1992-12-01 1999-06-15 Novo Nordisk As Processo para oxidar um substrato com uma enzima peroxidase ou um composto atuando como peroxidase na presença de uma fonte de peróxido de hidrogênio aditivo detergente e composição detergente
CA2154157C (en) 1993-01-18 1999-08-03 Fiona Susan Macbeath Machine dishwashing detergent compositions
DK0697036T3 (da) 1993-05-08 2000-01-31 Henkel Kgaa Sølvkorrosionsbeskyttelsesmiddel II
DE59405259D1 (de) 1993-05-08 1998-03-19 Henkel Kgaa Silberkorrosionsschutzmittel i
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
US5698504A (en) 1993-07-01 1997-12-16 The Procter & Gamble Company Machine dishwashing composition containing oxygen bleach and paraffin oil and benzotriazole compound silver tarnishing inhibitors
US5486303A (en) * 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
ATE245185T1 (de) * 1993-10-14 2003-08-15 Procter & Gamble Proteasen enthaltende bleichmittelzusammensetzungen
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US5691295A (en) * 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
EP1921147B1 (en) 1994-02-24 2011-06-08 Henkel AG & Co. KGaA Improved enzymes and detergents containing them
US5686014A (en) 1994-04-07 1997-11-11 The Procter & Gamble Company Bleach compositions comprising manganese-containing bleach catalysts
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
WO1995035362A1 (en) 1994-06-17 1995-12-28 Genencor International Inc. Cleaning compositions containing plant cell wall degrading enzymes and their use in cleaning methods
GB2294268A (en) 1994-07-07 1996-04-24 Procter & Gamble Bleaching composition for dishwasher use
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
DK0796317T3 (da) 1994-12-09 2000-06-05 Procter & Gamble Diacylperoxidpartikelholdig sammensætning til automatisk opvask
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
CA2217162A1 (en) 1995-05-05 1996-11-07 Unilever Plc Subtilisin variants
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
CN1192774A (zh) 1995-06-16 1998-09-09 普罗格特-甘布尔公司 包含钴催化剂的自动洗餐具用组合物
US5565422A (en) * 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
DE19530816A1 (de) * 1995-08-23 1997-02-27 Cognis Bio Umwelt Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
DE69635936T2 (de) 1995-09-18 2006-12-28 The Procter & Gamble Company, Cincinnati Riechstofffreisetzungssystem
MA24137A1 (fr) * 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
AU6226198A (en) 1997-03-07 1998-09-22 Procter & Gamble Company, The Improved methods of making cross-bridged macropolycycles
CN1262632C (zh) * 1997-03-07 2006-07-05 普罗格特-甘布尔公司 含有金属漂白催化剂和漂白活化剂和/或有机过羧酸的漂白组合物
EP0985042B1 (en) * 1997-06-04 2006-09-06 Genecor International, Inc. Protease enzymes for tough cleaning and/or spot and film reduction and compositions incorporating same
GB2327947A (en) 1997-08-02 1999-02-10 Procter & Gamble Detergent tablet
DE19736591A1 (de) 1997-08-22 1999-02-25 Peter Prof Dr Hegemann Verfahren zum Herstellen von Nukleinsäurepolymeren
ES2367505T3 (es) * 1997-10-23 2011-11-04 Danisco Us Inc. Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes.
MA24811A1 (fr) 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
DE69830743T2 (de) 1997-11-21 2006-04-27 Novozymes A/S Protease-varianten und zusammensetzungen
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
CA2313950A1 (en) 1997-12-24 1999-07-08 James T. Kellis, Jr. An improved method of assaying for a preferred enzyme and /or preferred detergent composition
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
MXPA00012241A (es) 1998-06-10 2002-06-04 Novozymes As Mananasas novedosas.
US6376450B1 (en) * 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
EP1135392A2 (en) 1998-11-30 2001-09-26 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
CN100415880C (zh) * 1999-05-20 2008-09-03 诺沃奇梅兹有限公司 在97与98位之间具有至少一个额外氨基酸残基的i-s1和i-s2亚组枯草杆菌酶
ATE408680T1 (de) * 1999-05-20 2008-10-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 128 und 129
US6946128B1 (en) * 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
MXPA02000837A (es) * 1999-07-22 2002-07-30 Procter & Gamble Conjugados de proteasa que tienen regiones epitopes protegidas estericamente.
AU6085800A (en) * 1999-07-22 2001-02-13 Procter & Gamble Company, The Subtilisin protease variants having amino acid substitutions in defined epitope regions
ATE400648T1 (de) 2000-08-11 2008-07-15 Genencor Int Transformation von bacillus, transformanten und mutanten-bibliotheken
US6440991B1 (en) 2000-10-02 2002-08-27 Wyeth Ethers of 7-desmethlrapamycin
CA2424720C (en) * 2000-10-02 2012-04-03 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6582914B1 (en) * 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
DK200101090A (da) * 2001-07-12 2001-08-16 Novozymes As Subtilase variants
CA2795814A1 (en) * 2001-12-31 2003-07-17 Genencor International, Inc. Proteases producing an altered immunogenic response and methods of making and using the same
CA2472725C (en) * 2002-01-16 2015-08-11 Genencor International, Inc. Multiply-substituted protease variants
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DE10260805A1 (de) 2002-12-23 2004-07-22 Geneart Gmbh Verfahren und Vorrichtung zum Optimieren einer Nucleotidsequenz zur Expression eines Proteins
ES2361838T3 (es) 2003-12-03 2011-06-22 Danisco Us Inc. Perhidrolasa.
US7417133B2 (en) * 2004-02-27 2008-08-26 Institut Pasteur Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same
EP2385112B1 (en) * 2005-07-08 2016-11-30 Novozymes A/S Subtilase variants
AR055444A1 (es) 2005-10-12 2007-08-22 Procter & Gamble Uso y produccion de metalopretasa neutra estable al almacenamiento
CA2652678A1 (en) 2006-06-05 2007-12-21 The Procter & Gamble Company Detergent compositions comprising polysaccharides as enzyme stabilizers
KR20150115023A (ko) * 2006-07-18 2015-10-13 다니스코 유에스 인크. 광범위한 온도에 걸쳐 활성인 프로테아제 변이형
EP2100947A1 (en) * 2008-03-14 2009-09-16 The Procter and Gamble Company Automatic dishwashing detergent composition
CN104694519B (zh) * 2008-06-06 2023-10-27 丹尼斯科美国公司 包含微生物蛋白酶变体的组合物和方法
BRPI0921827A2 (pt) * 2008-11-11 2016-09-27 Danisco Us Inc composições e métodos compreendendo uma variante de subtilisina
EP2362902B1 (en) * 2008-11-11 2012-10-24 Danisco US, Inc., Genencor Division Compositions and methods comprising a subtilisin variant
EP2362896A2 (en) * 2008-11-11 2011-09-07 Danisco US Inc. Bacillus subtilisin comprising one or more combinable mutations
MX339402B (es) * 2008-11-11 2016-05-25 Danisco Us Inc Composiciones y metodos que comprenden variantes de serina proteasa.
EP2480650B1 (en) * 2009-09-25 2017-03-22 Novozymes A/S Subtilase variants
EP4159833A3 (en) * 2009-12-09 2023-07-26 The Procter & Gamble Company Fabric and home care products
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
US20110281327A1 (en) * 2010-04-15 2011-11-17 Danisco Us Inc. Compositions And Methods Comprising Variant Proteases
EP3569611A1 (en) * 2013-04-23 2019-11-20 Novozymes A/S Liquid automatic dish washing detergent compositions with stabilised subtilisin

Also Published As

Publication number Publication date
CN102209778A (zh) 2011-10-05
JP2013240328A (ja) 2013-12-05
WO2010056640A3 (en) 2010-10-07
CN103396904A (zh) 2013-11-20
BR122013014156A2 (pt) 2015-07-14
MX383346B (es) 2025-03-13
US20150132825A1 (en) 2015-05-14
EP2589651A3 (en) 2013-08-28
CN103396904B (zh) 2015-12-23
JP2015164423A (ja) 2015-09-17
EP2647692A2 (en) 2013-10-09
JP2012508030A (ja) 2012-04-05
CN102209778B (zh) 2014-10-15
JP5911825B2 (ja) 2016-04-27
US20150031589A1 (en) 2015-01-29
RU2011123911A (ru) 2012-12-20
EP2589651A2 (en) 2013-05-08
JP5727378B2 (ja) 2015-06-03
AR073420A1 (es) 2010-11-03
BRPI0922084A2 (pt) 2015-01-27
CN104293751A (zh) 2015-01-21
WO2010056640A2 (en) 2010-05-20
CN104293751B (zh) 2018-11-27
EP2362897A2 (en) 2011-09-07
BRPI0922084B1 (pt) 2020-12-29
US10093887B2 (en) 2018-10-09
KR20110091671A (ko) 2011-08-12
CA2743047A1 (en) 2010-05-20
EP2647692A3 (en) 2014-01-22
JP2015177797A (ja) 2015-10-08
MX2011004818A (es) 2011-05-31
US20100192985A1 (en) 2010-08-05
US20190194577A1 (en) 2019-06-27
JP6021983B2 (ja) 2016-11-09

Similar Documents

Publication Publication Date Title
MX339402B (es) Composiciones y metodos que comprenden variantes de serina proteasa.
MX382899B (es) Composiciones y métodos que comprenden variantes de proteasa termolisina.
MX336737B (es) Composiciones y metodos que comprenden variantes de proteasa serina.
MX2013012690A (es) Composiciones y metodos que comprenden variantes de proteasa serina.
AR087745A1 (es) Composiciones y metodos que comprenden una variante de enzima lipolitica
MX338884B (es) Composiciones y metodos que comprenden variantes de proteasa.
MX2018016021A (es) Composiciones y metodos que comprenden variante de enzima lipolitica.
MX383345B (es) Composiciones y metodos que comprenden proteasas microbianas variantes.
MX371497B (es) Composiciones y metodos que comprenden una variante de enzima lipolitica.
AR070498A1 (es) Composicion detergente que comprende lipasa
MX342388B (es) Variantes y composiciones que comprenden variantes con alta estabilidad en presencia de un agente quelante.
CO6571886A2 (es) Antagonistas de pcsk9
MX379016B (es) Composiciones y metodos para tratar enfermedad de gaucher.
MX2018004683A (es) Composicion detergente que comprende variantes de amilasa y proteasa.
EA201001639A1 (ru) Композиции и способы их получения и применения
MX2010007867A (es) Composiciones de limpieza personal concentradas.
BRPI0923731A2 (pt) "formulações injetáveis de toxinas botulínicas".
MA32369B1 (fr) Composes de benzene sulfonamide thiazole et oxazole
MX390779B (es) Composición farmacéutica.
MX2012000475A (es) Variantes de plasminogeno y plasmina.
MX337248B (es) Variantes de plasminogeno y plasmina.
EA201201406A1 (ru) Фунгицидные смеси ii, содержащие хиназолины
JO3437B1 (ar) أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
MX341064B (es) Variantes de la familia il-1.
MX2011008179A (es) Peptidos para vacuna.

Legal Events

Date Code Title Description
FG Grant or registration