MX339402B - Composiciones y metodos que comprenden variantes de serina proteasa. - Google Patents

Composiciones y metodos que comprenden variantes de serina proteasa.

Info

Publication number
MX339402B
MX339402B MX2011004818A MX2011004818A MX339402B MX 339402 B MX339402 B MX 339402B MX 2011004818 A MX2011004818 A MX 2011004818A MX 2011004818 A MX2011004818 A MX 2011004818A MX 339402 B MX339402 B MX 339402B
Authority
MX
Mexico
Prior art keywords
serine protease
protease variants
compositions
methods
present
Prior art date
Application number
MX2011004818A
Other languages
English (en)
Other versions
MX2011004818A (es
Inventor
David A Estell
James T Kellis Jr
Ayrookaran J Poulose
Frits Goedegebuur
Wolfgang Aehle
Luis G Cascao-Pereira
Brian F Schmidt
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of MX2011004818A publication Critical patent/MX2011004818A/es
Publication of MX339402B publication Critical patent/MX339402B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609Protease or amylase in solid compositions only
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618Protease or amylase in liquid compositions only
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38636Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38654Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21062Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a métodos para fabricación por ingeniería de proteína y variantes de serina proteasa producidos de ellos. Específicamente, la presente invención proporciona variantes de serina proteasa que tienen una o más sustituciones como se compara con una serina proteasa de referencia. Además, la presente invención proporciona composiciones que comprenden estas variantes de serina proteasa. En algunas modalidades, la presente invención proporciona composiciones de limpieza que comprenden al menos una de estas variantes de serina proteasa.
MX2011004818A 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa. MX339402B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11354808P 2008-11-11 2008-11-11
US11355208P 2008-11-11 2008-11-11
US11354508P 2008-11-11 2008-11-11
US21880209P 2009-06-19 2009-06-19
PCT/US2009/063808 WO2010056640A2 (en) 2008-11-11 2009-11-10 Compositions and methods comprising serine protease variants

Publications (2)

Publication Number Publication Date
MX2011004818A MX2011004818A (es) 2011-05-31
MX339402B true MX339402B (es) 2016-05-25

Family

ID=42025792

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011004818A MX339402B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.
MX2015014217A MX383346B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2015014217A MX383346B (es) 2008-11-11 2009-11-10 Composiciones y metodos que comprenden variantes de serina proteasa.

Country Status (11)

Country Link
US (4) US20100192985A1 (es)
EP (3) EP2362897A2 (es)
JP (4) JP5727378B2 (es)
KR (1) KR20110091671A (es)
CN (3) CN104293751B (es)
AR (1) AR073420A1 (es)
BR (2) BR122013014156A2 (es)
CA (1) CA2743047A1 (es)
MX (2) MX339402B (es)
RU (1) RU2011123911A (es)
WO (1) WO2010056640A2 (es)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2368718T3 (es) * 1997-10-23 2011-11-21 Danisco Us Inc. Variantes de subtilisina con múltiples sustituciones.
ATE450606T1 (de) * 2002-01-16 2009-12-15 Genencor Int Mehrfachsubstituierte proteasevarianten
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
BRPI0915681A2 (pt) 2008-06-06 2015-08-04 Danisco Us Inc Composições e métodos compreendendo proteases microbianas variantes
AR073420A1 (es) * 2008-11-11 2010-11-03 Danisco Us Inc Variantes de serina proteasas, composiciones y metodos de limpieza que las comprenden
CN102652175B (zh) 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
JP6018044B2 (ja) * 2010-04-15 2016-11-02 ダニスコ・ユーエス・インク プロテアーゼ変異体を含む組成物及び方法
ES2745011T3 (es) * 2010-05-06 2020-02-27 Procter & Gamble Productos de consumo con variantes de proteasa
DE102010063458A1 (de) * 2010-12-17 2012-06-21 Henkel Ag & Co. Kgaa Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Amylase
BR112013028440A2 (pt) * 2011-05-05 2016-11-29 Procter & Gamble composições e métodos que compreendem variantes de serina protease
WO2012151480A2 (en) * 2011-05-05 2012-11-08 The Procter & Gamble Company Compositions and methods comprising serine protease variants
ES2707869T3 (es) * 2011-05-05 2019-04-05 Danisco Us Inc Composiciones y métodos comprendiendo variantes de serina proteasa
WO2013120948A1 (en) * 2012-02-17 2013-08-22 Novozymes A/S Subtilisin variants and polynucleotides encoding same
ES2701763T3 (es) * 2012-07-09 2019-02-25 Hoffmann La Roche Proteasa neutra producida de forma recombinante procedente de Paenibacillus polymyxa
CN104640981B (zh) * 2012-09-14 2017-08-04 天野酶制品株式会社 糖质氧化酶、其制备方法以及用途
EP3354728B1 (en) 2012-12-21 2020-04-22 Danisco US Inc. Alpha-amylase variants
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
US20160017305A1 (en) 2013-03-11 2016-01-21 Danisco Us Inc. Alpha-amylase combinatorial variants
US20160108387A1 (en) 2013-05-29 2016-04-21 Danisco Us Inc. Novel metalloproteases
WO2014194054A1 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
EP3110833B1 (en) 2013-05-29 2020-01-08 Danisco US Inc. Novel metalloproteases
EP3013956B1 (en) 2013-06-27 2023-03-01 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2014207228A1 (en) * 2013-06-27 2014-12-31 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2015057619A1 (en) 2013-10-15 2015-04-23 Danisco Us Inc. Clay granule
DK3068879T3 (da) 2013-11-14 2020-03-16 Danisco Us Inc Stabile enzymer opnået ved glykeringsreduktion
EP3080262B1 (en) 2013-12-13 2019-02-06 Danisco US Inc. Serine proteases of bacillus species
US10533165B2 (en) 2013-12-13 2020-01-14 Danisco Us Inc Serine proteases of the bacillus gibsonii-clade
CA2932498C (en) 2013-12-16 2023-03-14 E. I. Du Pont De Nemours And Company Use of poly alpha-1,3-glucan ethers as viscosity modifiers
EP3789407B1 (en) 2013-12-18 2024-07-24 Nutrition & Biosciences USA 4, Inc. Cationic poly alpha-1,3-glucan ethers
WO2015112338A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Method of treating textile fabrics
EP3097173B1 (en) 2014-01-22 2020-12-23 The Procter and Gamble Company Fabric treatment composition
WO2015112341A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Fabric treatment composition
EP3097174A1 (en) 2014-01-22 2016-11-30 The Procter & Gamble Company Method of treating textile fabrics
CN105992796A (zh) 2014-02-14 2016-10-05 纳幕尔杜邦公司 用于粘度调节的聚-α-1,3-1,6-葡聚糖
MX2016011467A (es) 2014-03-11 2016-11-16 Du Pont Poli alfa-1,3-glucano oxidado como mejorador de detergente.
EP4155398A1 (en) 2014-03-21 2023-03-29 Danisco US Inc. Serine proteases of bacillus species
EP3126480A4 (en) * 2014-04-01 2017-08-16 Novozymes A/S Detergent composition
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3158043B1 (en) 2014-06-19 2021-03-10 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3878960A1 (en) 2014-07-04 2021-09-15 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2016001450A2 (en) * 2014-07-04 2016-01-07 Novozymes A/S Subtilase variants and polynucleotides encoding same
GB201414130D0 (en) * 2014-08-08 2014-09-24 Agency Science Tech & Res Mutants of the bacteriophage lambda integrase
WO2016036209A1 (ko) * 2014-09-05 2016-03-10 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 향상된 미생물 및 이를 이용한 l-쓰레오닌 생산방법
PL3144385T3 (pl) * 2014-09-05 2020-12-14 Cj Cheiljedang Corporation Mikroorganizm o ulepszonej produktywności l-treoniny i sposób produkcji l-treoniny z jego wykorzystaniem
JP7017409B2 (ja) * 2014-10-10 2022-02-08 エンザイペプ ビー.ブイ. 加水分解に対する合成の比が改善したスブチリシン変異体を使用するペプチド断片縮合及び環化
US20170233710A1 (en) 2014-10-17 2017-08-17 Danisco Us Inc. Serine proteases of bacillus species
BR112017007949A2 (pt) 2014-10-24 2018-01-23 Danisco Us Inc método para produção de álcool pelo uso de uma tripeptidil-peptidase
EP3212662B1 (en) 2014-10-27 2020-04-08 Danisco US Inc. Serine proteases
CN107148472A (zh) * 2014-10-27 2017-09-08 丹尼斯科美国公司 芽孢杆菌属物种的丝氨酸蛋白酶
EP3212782B1 (en) 2014-10-27 2019-04-17 Danisco US Inc. Serine proteases
EP3212781B1 (en) 2014-10-27 2019-09-18 Danisco US Inc. Serine proteases
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
AT516457B1 (de) * 2014-11-07 2017-03-15 Erber Ag Polypeptid zur enzymatischen Detoxifizierung von Zearalenon, sowie isoliertes Polynukleotid, sowie Zusatzstoff, Verwendung und Verfahren desselben
BR112017010239A2 (pt) 2014-11-17 2018-01-02 Procter & Gamble composições para liberação de agente de benefício
US10260024B2 (en) * 2014-12-04 2019-04-16 Novozymes A/S Liquid cleaning compositions comprising protease variants
CN107075493B (zh) 2014-12-04 2020-09-01 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
US10760036B2 (en) * 2014-12-15 2020-09-01 Henkel Ag & Co. Kgaa Detergent composition comprising subtilase variants
CN107109450A (zh) 2014-12-23 2017-08-29 纳幕尔杜邦公司 酶促产生的纤维素
EP3611259A1 (en) * 2015-03-12 2020-02-19 Danisco US Inc. Compositions and methods comprising lg12-clade protease variants
EP3088505B1 (en) 2015-04-29 2020-06-03 The Procter and Gamble Company Method of treating a fabric
EP3088506B1 (en) 2015-04-29 2018-05-23 The Procter and Gamble Company Detergent composition
EP3088504B1 (en) 2015-04-29 2021-07-21 The Procter & Gamble Company Method of treating a fabric
PL3088503T3 (pl) 2015-04-29 2018-10-31 The Procter & Gamble Company Sposób prania tkanin
PL3088502T3 (pl) 2015-04-29 2018-10-31 The Procter & Gamble Company Sposób obróbki tkaniny
US20180112204A1 (en) 2015-05-13 2018-04-26 Danisco Us Inc. AprL-CLADE PROTEASE VARIANTS AND USES THEREOF
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
EP3307427B1 (en) 2015-06-09 2023-08-16 Danisco US Inc. Osmotic burst encapsulates
US11499146B2 (en) 2015-06-17 2022-11-15 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
CN108603183B (zh) 2015-11-05 2023-11-03 丹尼斯科美国公司 类芽孢杆菌属物种和芽孢杆菌属物种甘露聚糖酶
CN109072208A (zh) 2015-11-05 2018-12-21 丹尼斯科美国公司 类芽孢杆菌属物种甘露聚糖酶
WO2017077924A1 (ja) * 2015-11-06 2017-05-11 天野エンザイム株式会社 新規グルコースデヒドロゲナーゼ
JP7045313B2 (ja) 2015-11-13 2022-03-31 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
WO2017083229A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
WO2017089093A1 (en) 2015-11-25 2017-06-01 Unilever N.V. A liquid detergent composition
JP2019500058A (ja) 2015-12-09 2019-01-10 ダニスコ・ユーエス・インク α−アミラーゼ組み合わせ変異体
EP3390625B1 (en) 2015-12-18 2023-09-06 Danisco US Inc. Polypeptides with endoglucanase activity and uses thereof
EP3411477A4 (en) * 2016-02-06 2019-07-10 Novozymes A/S POLYPEPTIDES WITH PROTEASE ACTIVITY AND POLYNUCLEOTIDES FOR CODING THEREOF
CN109071615A (zh) 2016-03-04 2018-12-21 丹尼斯科美国公司 用于在微生物中产生蛋白质的工程化核糖体启动子
BR112018072530A2 (pt) * 2016-05-03 2019-03-26 Danisco Us Inc variantes de protease e usos das mesmas
CN109477112B (zh) 2016-05-31 2024-09-06 丹尼斯科美国公司 蛋白酶变体及其用途
CN110129298B (zh) * 2016-06-02 2021-08-03 天津科技大学 一种磷脂酶d突变体及其应用
MX2018015559A (es) 2016-06-17 2019-06-06 Danisco Us Inc Variantes de proteasa y sus usos.
EP3275988B1 (en) * 2016-07-26 2020-07-08 The Procter and Gamble Company Automatic dishwashing detergent composition
CN109689871B (zh) * 2016-09-15 2022-07-01 花王株式会社 突变丝状菌和使用其制造c4二羧酸的方法
US10961548B2 (en) * 2016-09-28 2021-03-30 Riken Diphosphomevalonate decarboxylase variant and method for producing olefin compound by using the same
CA3040585A1 (en) 2016-10-27 2018-05-03 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
CN106566818B (zh) * 2016-10-28 2019-05-17 中国农业科学院饲料研究所 酸性嗜热多聚半乳糖醛酸酶TePG28A及其编码基因和应用
US20190264138A1 (en) 2016-11-07 2019-08-29 Danisco Us Inc. Laundry detergent composition
US10550443B2 (en) 2016-12-02 2020-02-04 The Procter & Gamble Company Cleaning compositions including enzymes
DK3330349T3 (da) 2016-12-02 2024-07-15 Procter & Gamble Rengøringssammensætninger, der indbefatter enzymer
CA3044415C (en) 2016-12-02 2022-06-07 The Procter & Gamble Company Cleaning compositions including enzymes
EP3559226B1 (en) 2016-12-21 2023-01-04 Danisco US Inc. Bacillus gibsonii-clade serine proteases
WO2018118917A1 (en) 2016-12-21 2018-06-28 Danisco Us Inc. Protease variants and uses thereof
EP3569703A4 (en) * 2017-01-15 2020-11-18 Feed Research Institute Chinese Academy of Agricultural Sciences YEAPPA PHYTASE MUTANTS WITH ENHANCED GASTRIC PROTEIN RESISTANCE AND ACID RESISTANCE AS WELL AS INCREASED CATALYTIC EFFICIENCY
US10988751B2 (en) * 2017-02-01 2021-04-27 Riken Diphosphomevalonate decarboxylase variant and method for manufacturing olefin compound using same
ES3014686T3 (en) 2017-02-20 2025-04-24 Novozymes As Lipolytic enzyme for use in baking
US11453871B2 (en) 2017-03-15 2022-09-27 Danisco Us Inc. Trypsin-like serine proteases and uses thereof
EP3601515A1 (en) 2017-03-31 2020-02-05 Danisco US Inc. Delayed release enzyme formulations for bleach-containing detergents
WO2018190398A1 (ja) * 2017-04-13 2018-10-18 協和発酵バイオ株式会社 テアニンの製造方法
CN110582568B (zh) * 2017-05-03 2024-04-16 弗门尼舍有限公司 用于产生补身醇及其混合物的倍半萜合酶
CA3067837A1 (en) 2017-06-30 2019-01-03 Danisco Us Inc Low-agglomeration, enzyme-containing particles
CN111344401A (zh) * 2017-09-13 2020-06-26 纳幕尔杜邦公司 工程化的葡糖基转移酶
EP3703661A1 (en) 2017-11-02 2020-09-09 Danisco US Inc. Freezing point depressed solid matrix compositions for melt granulation of enzymes
CN111373039A (zh) * 2017-11-29 2020-07-03 丹尼斯科美国公司 具有改善的稳定性的枯草杆菌蛋白酶变体
EP3502245B1 (en) * 2017-12-19 2025-03-05 The Procter & Gamble Company Automatic dishwashing detergent composition
MX2020006518A (es) 2017-12-21 2020-10-28 Danisco Us Inc Gránulos de fusión en caliente, que contienen enzimas, que comprenden un desecante termotolerante.
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
JP7124338B2 (ja) * 2018-02-27 2022-08-24 味の素株式会社 変異型グルタチオン合成酵素、及び、γ-グルタミルバリルグリシンの製造法
BR112020020285A2 (pt) 2018-04-06 2021-01-19 Braskem S.A. Mutantes de enzima dependentes de nadh para converter acetona em isopropanol
WO2019232025A2 (en) * 2018-05-29 2019-12-05 Massachusetts Institute Of Technology Microbial engineering for the production of isoprenoids
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US20210363470A1 (en) 2018-06-19 2021-11-25 Danisco Us Inc Subtilisin variants
EP3599282B1 (en) * 2018-07-24 2021-03-17 Evonik Operations GmbH Method for the fermentative production of l-lysine
WO2020047215A1 (en) 2018-08-30 2020-03-05 Danisco Us Inc Enzyme-containing granules
EP3856882A1 (en) 2018-09-27 2021-08-04 Danisco US Inc. Compositions for medical instrument cleaning
JP7078900B2 (ja) * 2018-10-05 2022-06-01 トヨタ自動車株式会社 形質転換酵母及びこれを用いたエタノールの製造方法
WO2020112599A1 (en) 2018-11-28 2020-06-04 Danisco Us Inc Subtilisin variants having improved stability
CN109481336B (zh) * 2018-12-19 2021-10-26 广州立白企业集团有限公司 口腔护理组合物及其应用
CN109456957B (zh) * 2018-12-19 2021-01-01 广州立白企业集团有限公司 蛋白酶变体、液体洗涤剂组合物及其应用
US10829746B2 (en) * 2019-01-23 2020-11-10 Evonik Operations Gmbh Method for the fermentative production of L-lysine
EP3976775A1 (en) 2019-05-24 2022-04-06 The Procter & Gamble Company Automatic dishwashing detergent composition
CN114174504A (zh) 2019-05-24 2022-03-11 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP3980517A1 (en) 2019-06-06 2022-04-13 Danisco US Inc. Methods and compositions for cleaning
US11492571B2 (en) 2019-10-24 2022-11-08 The Procter & Gamble Company Automatic dishwashing detergent composition comprising a protease
KR102316445B1 (ko) * 2019-11-29 2021-10-26 씨제이제일제당 주식회사 신규 세린 프로테아제 변이체
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
CN116323932A (zh) * 2020-08-28 2023-06-23 诺维信公司 具有改善的溶解度的蛋白酶变体
CA3191867A1 (en) * 2020-08-28 2022-03-03 Codexis, Inc. Engineered protease variants
WO2022165107A1 (en) 2021-01-29 2022-08-04 Danisco Us Inc Compositions for cleaning and methods related thereto
KR20230144058A (ko) * 2021-02-12 2023-10-13 프레제니우스 카비 입섬 에스. 알. 엘. 서브틸리신 변이체 및 그의 용도
CN112725316B (zh) * 2021-03-04 2022-09-06 宁夏夏盛实业集团有限公司 碱性蛋白酶2018突变体及其制备方法
EP4363565A1 (en) 2021-06-30 2024-05-08 Danisco US Inc. Variant lipases and uses thereof
US20240384205A1 (en) 2021-09-03 2024-11-21 Danisco Us Inc. Laundry compositions for cleaning
CN117957318A (zh) 2021-09-13 2024-04-30 丹尼斯科美国公司 含有生物活性物质的颗粒
EP4448749A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and methods of use
US20250051748A1 (en) 2021-12-16 2025-02-13 Danisco Us Inc. Subtilisin variants and methods of use
CN118715318A (zh) 2021-12-16 2024-09-27 丹尼斯科美国公司 枯草杆菌蛋白酶变体及其用途
US20250163396A1 (en) 2022-03-01 2025-05-22 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
US12416044B2 (en) * 2022-03-21 2025-09-16 Abclonal Science, Inc. T4 DNA ligase variants with increased ligation efficiency
PE20251535A1 (es) 2022-05-14 2025-06-05 Novozymes As Composiciones y metodos para prevenir, tratar, suprimir y/o eliminar infecciones e infestaciones fitopatogenas
WO2023250301A1 (en) 2022-06-21 2023-12-28 Danisco Us Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
DE102022208890A1 (de) 2022-08-16 2024-02-22 Henkel Ag & Co. Kgaa Leistungsverbesserte protease-varianten ix
DE102022208891A1 (de) 2022-08-16 2024-02-22 Henkel Ag & Co. Kgaa Leistungsverbesserte protease-varianten x
EP4581137A1 (en) 2022-09-02 2025-07-09 Danisco Us Inc Mannanase variants and methods of use
CN120112635A (zh) 2022-09-02 2025-06-06 丹尼斯科美国公司 枯草杆菌蛋白酶变体及其相关方法
CN119855892A (zh) 2022-09-02 2025-04-18 丹尼斯科美国公司 洗涤剂组合物及其相关方法
WO2024094733A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
CN120153068A (zh) 2022-11-04 2025-06-13 巴斯夫欧洲公司 用于在洗涤剂组合物中使用的具有蛋白酶活性的多肽
EP4612286A1 (en) 2022-11-04 2025-09-10 Basf Se Polypeptides having protease activity for use in detergent compositions
CN120303400A (zh) * 2022-11-09 2025-07-11 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP4658776A1 (en) 2023-02-01 2025-12-10 Danisco US Inc. Subtilisin variants and methods of use
CN116064490B (zh) * 2023-03-05 2025-12-12 中国农业科学院北京畜牧兽医研究所 一种提高碱性蛋白酶热稳定性的方法及突变体ThAPT3-M3、ThAPT3-M4和应用
WO2024186819A1 (en) 2023-03-06 2024-09-12 Danisco Us Inc. Subtilisin variants and methods of use
CN120813242A (zh) 2023-03-16 2025-10-17 营养与生物科学美国第四公司 用于清洁和臭味控制的短芽孢杆菌发酵物提取物及其用途
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
CN117535273B (zh) * 2023-11-07 2024-06-07 南京诺唯赞生物科技股份有限公司 温敏型碱性蛋白酶变体及其应用
EP4624572A1 (en) 2024-03-27 2025-10-01 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202374A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202369A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202382A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in cleaning compositions
WO2025202372A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202379A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
CN119530204B (zh) * 2024-12-09 2025-11-04 湖北大学 水解胶原蛋白的酶及应用

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (es) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB2048606B (en) 1979-02-28 1983-03-16 Barr & Stroud Ltd Optical scanning system
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
GR76237B (es) * 1981-08-08 1984-08-04 Procter & Gamble
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5763257A (en) 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US5972682A (en) * 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK171161B1 (da) 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
US5024943A (en) 1985-11-07 1991-06-18 Gist-Brocades Regulatory region cloning and analysis plasmid for bacillus
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
EP0258068B1 (en) 1986-08-29 1994-08-31 Novo Nordisk A/S Enzymatic detergent additive
GB8629837D0 (en) 1986-12-13 1987-01-21 Interox Chemicals Ltd Bleach activation
EP0322429B1 (en) 1987-05-29 1994-10-19 Genencor International, Inc. Cutinase cleaning composition
ES2076939T3 (es) 1987-08-28 1995-11-16 Novo Nordisk As Lipasa recombinante de humicola y procedimiento para la produccion de lipasas recombinantes de humicola.
JPH0633189Y2 (ja) 1987-09-14 1994-08-31 立山アルミニウム工業株式会社 サッシ枠の連結装置
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
JP2624859B2 (ja) 1988-01-07 1997-06-25 ノボ‐ノルディスク アクティーゼルスカブ 酵素洗剤
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
EP0342177B1 (en) 1988-05-12 1995-07-12 The Procter & Gamble Company Heavy duty liquid laundry detergents containing anionic and nonionic surfactant, builder and proteolytic enzyme
US4883195A (en) * 1988-11-02 1989-11-28 Restaurant Technology, Inc. Pizza container
WO1990009446A1 (en) 1989-02-17 1990-08-23 Plant Genetic Systems N.V. Cutinase
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
DE4111321A1 (de) * 1990-04-14 1991-10-17 Kali Chemie Ag Alkalische bacillus-lipasen, hierfuer codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren
US5354559A (en) 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
EP0495257B1 (en) 1991-01-16 2002-06-12 The Procter & Gamble Company Compact detergent compositions with high activity cellulase
GB9108136D0 (en) 1991-04-17 1991-06-05 Unilever Plc Concentrated detergent powder compositions
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
KR100303620B1 (ko) 1992-12-01 2001-11-22 피아 스타르 효소반응의증강법
CA2154157C (en) * 1993-01-18 1999-08-03 Fiona Susan Macbeath Machine dishwashing detergent compositions
DK0697035T3 (da) 1993-05-08 1998-09-28 Henkel Kgaa Sølvbeskyttelsesmiddel med korrosion I
ES2134944T3 (es) 1993-05-08 1999-10-16 Henkel Kgaa Agente anticorrosivo de plata ii.
DK77393D0 (da) * 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
US5698504A (en) * 1993-07-01 1997-12-16 The Procter & Gamble Company Machine dishwashing composition containing oxygen bleach and paraffin oil and benzotriazole compound silver tarnishing inhibitors
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
CN1177921C (zh) * 1993-10-14 2004-12-01 普罗格特-甘布尔公司 含有蛋白酶的漂白组合物
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
DK0701605T3 (da) 1994-02-24 2008-07-28 Henkel Ag & Co Kgaa Forbedrede enzymer og detergenter indeholdende disse
US5686014A (en) * 1994-04-07 1997-11-11 The Procter & Gamble Company Bleach compositions comprising manganese-containing bleach catalysts
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
ES2180645T3 (es) 1994-06-17 2003-02-16 Genencor Int Metodo de limpieza basado en composiciones que contienen una enzima capaz de degradar las paredes celulares de las plantas y su uso en metodos de limpieza.
GB2294268A (en) 1994-07-07 1996-04-24 Procter & Gamble Bleaching composition for dishwasher use
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5489392A (en) * 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
US5691297A (en) * 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
ATE190090T1 (de) 1994-12-09 2000-03-15 Procter & Gamble Diacylperoxydteilchen enthaltende zusammensetzungen für automatische geschirreinigung
US5534179A (en) * 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
CA2217162A1 (en) 1995-05-05 1996-11-07 Unilever Plc Subtilisin variants
ES2158320T3 (es) 1995-06-16 2001-09-01 Procter & Gamble Composiciones para lavavajillas automaticos que comprenden catalizadores de cobalto.
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
DE19530816A1 (de) 1995-08-23 1997-02-27 Cognis Bio Umwelt Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
ATE214729T1 (de) 1995-09-18 2002-04-15 Procter & Gamble Freisetzungssysteme
MA24137A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
CA2282466C (en) * 1997-03-07 2005-09-20 The Procter & Gamble Company Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids
CN1134443C (zh) 1997-03-07 2004-01-14 普罗格特-甘布尔公司 制备交联桥大环化合物的改进方法
US6369011B1 (en) * 1997-06-04 2002-04-09 The Procter & Gamble Company Protease enzymes for tough cleaning and/or spot and film reduction and compositions incorporating same
GB2327947A (en) 1997-08-02 1999-02-10 Procter & Gamble Detergent tablet
DE19736591A1 (de) 1997-08-22 1999-02-25 Peter Prof Dr Hegemann Verfahren zum Herstellen von Nukleinsäurepolymeren
MA24811A1 (fr) 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
ES2368718T3 (es) * 1997-10-23 2011-11-21 Danisco Us Inc. Variantes de subtilisina con múltiples sustituciones.
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
CN1279715A (zh) 1997-11-21 2001-01-10 诺沃挪第克公司 蛋白酶变体及组合物
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
DK1042501T3 (da) 1997-12-24 2007-08-13 Genencor Int Fremgangsmåde til analyse af vaskeevnen af et enzym
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
EP2284272B1 (en) 1998-06-10 2014-08-13 Novozymes A/S Mannanases
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
WO2000032601A2 (en) 1998-11-30 2000-06-08 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
ATE408680T1 (de) * 1999-05-20 2008-10-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 128 und 129
MXPA01011836A (es) * 1999-05-20 2002-06-21 Novozymes As Enzimas subtilasas de los sub-grupos i-s1 e i-s2 que tienen al menos un residuo de un aminoacido adicional entre las posiciones 97 y 98.
BR0012660A (pt) * 1999-07-22 2002-04-09 Procter & Gamble Variante de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
US6946128B1 (en) * 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
BR0012692A (pt) * 1999-07-22 2002-04-09 Procter & Gamble Conjugado de protease, composição de limpeza e composição de tratamento pessoal
ATE400648T1 (de) 2000-08-11 2008-07-15 Genencor Int Transformation von bacillus, transformanten und mutanten-bibliotheken
US6440991B1 (en) * 2000-10-02 2002-08-27 Wyeth Ethers of 7-desmethlrapamycin
WO2002040997A2 (en) * 2000-10-02 2002-05-23 Genencor International, Inc. Production and use of proteins producing an altered immunogenic response
US6582914B1 (en) * 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
DK200101090A (da) * 2001-07-12 2001-08-16 Novozymes As Subtilase variants
US7332320B2 (en) * 2001-12-31 2008-02-19 Genencor International, Inc. Protease producing an altered immunogenic response and methods of making and using the same
ATE450606T1 (de) * 2002-01-16 2009-12-15 Genencor Int Mehrfachsubstituierte proteasevarianten
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DE10260805A1 (de) * 2002-12-23 2004-07-22 Geneart Gmbh Verfahren und Vorrichtung zum Optimieren einer Nucleotidsequenz zur Expression eines Proteins
WO2005056782A2 (en) 2003-12-03 2005-06-23 Genencor International, Inc. Perhydrolase
US7417133B2 (en) * 2004-02-27 2008-08-26 Institut Pasteur Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same
CN103555697A (zh) * 2005-07-08 2014-02-05 诺维信公司 枯草蛋白酶变体
JP5507843B2 (ja) 2005-10-12 2014-05-28 ジェネンコー・インターナショナル・インク 保存安定的な中性金属プロテアーゼの使用及び生産
BRPI0712374A2 (pt) 2006-06-05 2012-06-12 Procter & Gamble estabilizante de enzimas
NZ573467A (en) 2006-07-18 2012-02-24 Danisco Us Inc Genencor Div Subtilisin variants active over a broad temperature range
EP2100947A1 (en) 2008-03-14 2009-09-16 The Procter and Gamble Company Automatic dishwashing detergent composition
BRPI0915681A2 (pt) * 2008-06-06 2015-08-04 Danisco Us Inc Composições e métodos compreendendo proteases microbianas variantes
CA2743060C (en) * 2008-11-11 2017-03-07 Danisco Us Inc. Compositions and methods comprising a subtilisin variant
AR073420A1 (es) * 2008-11-11 2010-11-03 Danisco Us Inc Variantes de serina proteasas, composiciones y metodos de limpieza que las comprenden
BRPI0921827A2 (pt) * 2008-11-11 2016-09-27 Danisco Us Inc composições e métodos compreendendo uma variante de subtilisina
CN102209775A (zh) * 2008-11-11 2011-10-05 丹尼斯科美国公司 包含一种或多种可组合的突变的芽孢杆菌属枯草杆菌蛋白酶
MX339581B (es) * 2009-09-25 2016-06-01 Novozymes As Variantes de subtilasa.
CN102652175B (zh) * 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
JP6018044B2 (ja) * 2010-04-15 2016-11-02 ダニスコ・ユーエス・インク プロテアーゼ変異体を含む組成物及び方法
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
WO2014173980A2 (en) * 2013-04-23 2014-10-30 Novozymes A/S Liquid automatic dish washing detergent compositions

Also Published As

Publication number Publication date
US20150031589A1 (en) 2015-01-29
CN103396904A (zh) 2013-11-20
RU2011123911A (ru) 2012-12-20
CN103396904B (zh) 2015-12-23
AR073420A1 (es) 2010-11-03
US20190194577A1 (en) 2019-06-27
CN102209778A (zh) 2011-10-05
US10093887B2 (en) 2018-10-09
BRPI0922084B1 (pt) 2020-12-29
KR20110091671A (ko) 2011-08-12
JP2015177797A (ja) 2015-10-08
JP2012508030A (ja) 2012-04-05
MX2011004818A (es) 2011-05-31
BR122013014156A2 (pt) 2015-07-14
BRPI0922084A2 (pt) 2015-01-27
EP2647692A3 (en) 2014-01-22
JP5911825B2 (ja) 2016-04-27
US20100192985A1 (en) 2010-08-05
EP2589651A2 (en) 2013-05-08
WO2010056640A3 (en) 2010-10-07
CN104293751B (zh) 2018-11-27
EP2647692A2 (en) 2013-10-09
CN104293751A (zh) 2015-01-21
EP2589651A3 (en) 2013-08-28
WO2010056640A2 (en) 2010-05-20
US20150132825A1 (en) 2015-05-14
MX383346B (es) 2025-03-13
CA2743047A1 (en) 2010-05-20
JP2015164423A (ja) 2015-09-17
JP2013240328A (ja) 2013-12-05
JP5727378B2 (ja) 2015-06-03
EP2362897A2 (en) 2011-09-07
CN102209778B (zh) 2014-10-15
JP6021983B2 (ja) 2016-11-09

Similar Documents

Publication Publication Date Title
MX339402B (es) Composiciones y metodos que comprenden variantes de serina proteasa.
MX382899B (es) Composiciones y métodos que comprenden variantes de proteasa termolisina.
MX336737B (es) Composiciones y metodos que comprenden variantes de proteasa serina.
MX338925B (es) Composiciones y metodos que comprenden variantes de proteasa serina.
AR087745A1 (es) Composiciones y metodos que comprenden una variante de enzima lipolitica
MX338884B (es) Composiciones y metodos que comprenden variantes de proteasa.
MX2018016021A (es) Composiciones y metodos que comprenden variante de enzima lipolitica.
MX383345B (es) Composiciones y metodos que comprenden proteasas microbianas variantes.
MX371497B (es) Composiciones y metodos que comprenden una variante de enzima lipolitica.
AR070498A1 (es) Composicion detergente que comprende lipasa
MX342388B (es) Variantes y composiciones que comprenden variantes con alta estabilidad en presencia de un agente quelante.
CO6571886A2 (es) Antagonistas de pcsk9
MX379016B (es) Composiciones y metodos para tratar enfermedad de gaucher.
BR112016005286A2 (pt) composições e métodos compreendendo variantes de protease do clado lg12
MX2018004683A (es) Composicion detergente que comprende variantes de amilasa y proteasa.
EA201001639A1 (ru) Композиции и способы их получения и применения
BRPI0923731A2 (pt) "formulações injetáveis de toxinas botulínicas".
MA32369B1 (fr) Composes de benzene sulfonamide thiazole et oxazole
MX390779B (es) Composición farmacéutica.
MX2012000475A (es) Variantes de plasminogeno y plasmina.
MX2013007791A (es) Variantes de plasminogeno y plasmina.
JO3118B1 (ar) تراكيب وطرق لبروتين c5 المتمم يستهدف الأجسام المضادة
HN2006011218A (es) Composiciones de tigeciclina y métodos de preparación
JO3437B1 (ar) أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
MX341064B (es) Variantes de la familia il-1.

Legal Events

Date Code Title Description
FG Grant or registration