BR9913284A - Métodos para administrar peptìdeos insulinotrópicos - Google Patents
Métodos para administrar peptìdeos insulinotrópicosInfo
- Publication number
- BR9913284A BR9913284A BR9913284-2A BR9913284A BR9913284A BR 9913284 A BR9913284 A BR 9913284A BR 9913284 A BR9913284 A BR 9913284A BR 9913284 A BR9913284 A BR 9913284A
- Authority
- BR
- Brazil
- Prior art keywords
- administering
- methods
- insulinotropic peptides
- peptide
- glucagon
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
Patente de Invenção: <B>"MéTODOS PARA ADMINISTRAR PEPTìDEOS INSULINOTRóPICOS"<D>. A invenção reivindicada refere-se a um método de administrar moléculas de peptídeo-1 tipo glucagon por inalação, um método para tratar diabetes administrando moléculas de peptídeo-1 tipo glucagon por inalação, em um método para tratar hiperglicemia administrando moléculas de peptídeo-1 tipo glucagon por inalação.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9827398P | 1998-08-28 | 1998-08-28 | |
US10001298P | 1998-09-11 | 1998-09-11 | |
PCT/US1999/019348 WO2000012116A1 (en) | 1998-08-28 | 1999-08-24 | Method for administering insulinotropic peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9913284A true BR9913284A (pt) | 2001-05-15 |
Family
ID=26794577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9913284-2A BR9913284A (pt) | 1998-08-28 | 1999-08-24 | Métodos para administrar peptìdeos insulinotrópicos |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0997151B1 (pt) |
JP (1) | JP2002523466A (pt) |
KR (1) | KR20010073033A (pt) |
CN (1) | CN1314818A (pt) |
AR (1) | AR022368A1 (pt) |
AT (1) | ATE347902T1 (pt) |
AU (1) | AU764371B2 (pt) |
BR (1) | BR9913284A (pt) |
CA (1) | CA2341454A1 (pt) |
CO (1) | CO5090908A1 (pt) |
CZ (1) | CZ2001690A3 (pt) |
DE (1) | DE69934380D1 (pt) |
EA (1) | EA200100289A1 (pt) |
HR (1) | HRP20010141A2 (pt) |
HU (1) | HUP0103369A3 (pt) |
IL (1) | IL141241A0 (pt) |
NO (1) | NO20010982L (pt) |
PE (1) | PE20001031A1 (pt) |
PL (1) | PL346317A1 (pt) |
TR (1) | TR200100600T2 (pt) |
WO (1) | WO2000012116A1 (pt) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
WO2001051071A2 (en) * | 2000-01-11 | 2001-07-19 | Novo Nordisk A/S | Transepithelial delivery of glp-1 derivatives |
US6540983B1 (en) * | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
WO2001093837A2 (en) * | 2000-06-08 | 2001-12-13 | Eli Lilly And Company | Protein powder for pulmonary delivery |
NZ523693A (en) * | 2000-07-10 | 2004-08-27 | Chiron Corp | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
AU2002308706A1 (en) * | 2001-06-01 | 2002-12-16 | Eli Lilly And Company | Glp-1 formulations with protracted time action |
US7238671B2 (en) | 2001-10-18 | 2007-07-03 | Bristol-Myers Squibb Company | Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions |
WO2003033671A2 (en) | 2001-10-18 | 2003-04-24 | Bristol-Myers Squibb Company | Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions |
EP1997829A1 (en) | 2001-12-21 | 2008-12-03 | Human Genome Sciences, Inc. | Albumin fusion proteins |
CA2479751C (en) | 2002-03-20 | 2008-06-03 | Trent Poole | Inhalation apparatus |
JP4828940B2 (ja) * | 2002-08-01 | 2011-11-30 | マンカインド コーポレイション | 細胞輸送組成物およびこれらの使用 |
US8921311B2 (en) | 2003-08-01 | 2014-12-30 | Mannkind Corporation | Method for treating hyperglycemia |
RU2006120079A (ru) | 2003-12-18 | 2008-01-27 | Ново Нордиск А/С (DK) | Производные глюкагоноподобного пептида-1 (glp-1) |
KR101273120B1 (ko) | 2004-08-20 | 2013-06-13 | 맨카인드 코포레이션 | 다이케토피페라진 합성의 촉매 작용 |
KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
KR100704447B1 (ko) * | 2005-05-16 | 2007-04-09 | 정용현 | 3단계로 코팅되는 김치 유산균의 코팅방법 및 그로부터 제조된 코팅된 김치유산균 및 코팅된 김치 유산균이 함유된 조성물 |
KR101486397B1 (ko) | 2005-09-14 | 2015-01-28 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
HUE029798T2 (en) * | 2005-11-04 | 2017-03-28 | Glaxosmithkline Llc | Methods of administering hypoglycemic agents |
ES2390286T3 (es) | 2005-12-16 | 2012-11-08 | Nektar Therapeutics | Conjugados poliméricos de GLP-1 |
BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
PE20121528A1 (es) * | 2006-09-13 | 2012-12-12 | Smithkline Beecham Corp | Metodos para administrar agentes hipoglucemiantes de larga duracion |
EP2502618A3 (en) * | 2007-04-30 | 2012-10-03 | Novo Nordisk A/S | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
JP2009019027A (ja) * | 2007-07-16 | 2009-01-29 | Hanmi Pharmaceutical Co Ltd | アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体 |
PL2211842T3 (pl) * | 2007-10-24 | 2015-12-31 | Mannkind Corp | Preparat suchego proszku do inhalacji zawierający glp-1 do stosowania w leczeniu hiperglikemii i cukrzycy w podawaniu płucnym |
CN104491962B (zh) | 2008-06-13 | 2018-10-23 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PT2379100E (pt) | 2009-01-08 | 2015-02-09 | Mannkind Corp | Tratamento de hiperglicemia com glp-1 |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
US8734845B2 (en) | 2009-06-12 | 2014-05-27 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
US9016147B2 (en) | 2009-11-03 | 2015-04-28 | Mannkind Corporation | Apparatus and method for simulating inhalation efforts |
EP2582421A1 (en) | 2010-06-21 | 2013-04-24 | MannKind Corporation | Dry powder drug delivery system and methods |
SG10201606220QA (en) | 2011-04-01 | 2016-09-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
KR20140095483A (ko) | 2011-10-24 | 2014-08-01 | 맨카인드 코포레이션 | 통증을 치료하기 위한 방법 및 조성물 |
JP6312262B2 (ja) | 2012-07-12 | 2018-04-18 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
SG11201507564PA (en) | 2013-03-15 | 2015-10-29 | Mannkind Corp | Microcrystalline diketopiperazine compositions and methods |
AU2014290438B2 (en) | 2013-07-18 | 2019-11-07 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
WO2018155254A1 (ja) | 2017-02-21 | 2018-08-30 | Jfeスチール株式会社 | 高炭素熱延鋼板およびその製造方法 |
GB201917723D0 (en) | 2019-12-04 | 2020-01-15 | Nv Rose Llc | Stable liquid formulations of glucagon-like peptide 1 or analogues thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545618A (en) * | 1990-01-24 | 1996-08-13 | Buckley; Douglas I. | GLP-1 analogs useful for diabetes treatment |
DK36492D0 (da) * | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Praeparat |
HU225496B1 (en) * | 1993-04-07 | 2007-01-29 | Scios Inc | Pharmaceutical compositions of prolonged delivery, containing peptides |
US5512549A (en) * | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
RU2214419C2 (ru) * | 1996-08-30 | 2003-10-20 | Ново Нордиск А/С | Glp-1 производные |
UA65549C2 (uk) * | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
AU748756B2 (en) * | 1997-07-18 | 2002-06-13 | Infimed Therapeutics, Inc. | Biodegradable macromers for the controlled release of biologically active substances |
-
1999
- 1999-08-24 EA EA200100289A patent/EA200100289A1/ru unknown
- 1999-08-24 AR ARP990104231A patent/AR022368A1/es unknown
- 1999-08-24 CZ CZ2001690A patent/CZ2001690A3/cs unknown
- 1999-08-24 CA CA002341454A patent/CA2341454A1/en not_active Abandoned
- 1999-08-24 CO CO99053457A patent/CO5090908A1/es unknown
- 1999-08-24 JP JP2000567230A patent/JP2002523466A/ja not_active Withdrawn
- 1999-08-24 KR KR1020017002518A patent/KR20010073033A/ko not_active Application Discontinuation
- 1999-08-24 IL IL14124199A patent/IL141241A0/xx unknown
- 1999-08-24 PL PL99346317A patent/PL346317A1/xx not_active Application Discontinuation
- 1999-08-24 BR BR9913284-2A patent/BR9913284A/pt not_active IP Right Cessation
- 1999-08-24 AU AU55841/99A patent/AU764371B2/en not_active Ceased
- 1999-08-24 TR TR2001/00600T patent/TR200100600T2/xx unknown
- 1999-08-24 HU HU0103369A patent/HUP0103369A3/hu unknown
- 1999-08-24 CN CN99810174A patent/CN1314818A/zh active Pending
- 1999-08-24 WO PCT/US1999/019348 patent/WO2000012116A1/en not_active Application Discontinuation
- 1999-08-25 EP EP99306733A patent/EP0997151B1/en not_active Revoked
- 1999-08-25 AT AT99306733T patent/ATE347902T1/de not_active IP Right Cessation
- 1999-08-25 DE DE69934380T patent/DE69934380D1/de not_active Expired - Lifetime
- 1999-08-25 PE PE1999000857A patent/PE20001031A1/es not_active Application Discontinuation
-
2001
- 2001-02-27 NO NO20010982A patent/NO20010982L/no not_active Application Discontinuation
- 2001-02-27 HR HR20010141A patent/HRP20010141A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2341454A1 (en) | 2000-03-09 |
HUP0103369A2 (hu) | 2002-02-28 |
HUP0103369A3 (en) | 2002-03-28 |
NO20010982L (no) | 2001-04-27 |
HRP20010141A2 (en) | 2002-02-28 |
IL141241A0 (en) | 2002-03-10 |
ATE347902T1 (de) | 2007-01-15 |
EA200100289A1 (ru) | 2001-10-22 |
PL346317A1 (en) | 2002-01-28 |
CZ2001690A3 (cs) | 2002-04-17 |
DE69934380D1 (de) | 2007-01-25 |
EP0997151A3 (en) | 2000-09-20 |
AU5584199A (en) | 2000-03-21 |
CN1314818A (zh) | 2001-09-26 |
AU764371B2 (en) | 2003-08-14 |
WO2000012116A1 (en) | 2000-03-09 |
JP2002523466A (ja) | 2002-07-30 |
KR20010073033A (ko) | 2001-07-31 |
EP0997151A2 (en) | 2000-05-03 |
NO20010982D0 (no) | 2001-02-27 |
PE20001031A1 (es) | 2000-10-12 |
EP0997151B1 (en) | 2006-12-13 |
TR200100600T2 (tr) | 2001-07-23 |
AR022368A1 (es) | 2002-09-04 |
CO5090908A1 (es) | 2001-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007. |