HRP20201595T1 - Anti-pd-l1 protutijela i njihova uporaba - Google Patents

Anti-pd-l1 protutijela i njihova uporaba Download PDF

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Publication number
HRP20201595T1
HRP20201595T1 HRP20201595TT HRP20201595T HRP20201595T1 HR P20201595 T1 HRP20201595 T1 HR P20201595T1 HR P20201595T T HRP20201595T T HR P20201595TT HR P20201595 T HRP20201595 T HR P20201595T HR P20201595 T1 HRP20201595 T1 HR P20201595T1
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HR
Croatia
Prior art keywords
hvr
antibody
seq
cancer
sequence
Prior art date
Application number
HRP20201595TT
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English (en)
Croatian (hr)
Inventor
Horacio G. Nastri
Christel IFFLAND
Olivier Leger
Qi AN
Mark Cartwright
Sean D. Mckenna
Vanita D. Sood
Gang Hao
Original Assignee
Merck Patent Gmbh
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47221305&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20201595(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HRP20201595T1 publication Critical patent/HRP20201595T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
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HRP20201595TT 2011-11-28 2012-11-21 Anti-pd-l1 protutijela i njihova uporaba HRP20201595T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161563903P 2011-11-28 2011-11-28
PCT/EP2012/004822 WO2013079174A1 (en) 2011-11-28 2012-11-21 Anti-pd-l1 antibodies and uses thereof
EP12790432.4A EP2785375B1 (en) 2011-11-28 2012-11-21 Anti-pd-l1 antibodies and uses thereof

Publications (1)

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HRP20201595T1 true HRP20201595T1 (hr) 2020-12-11

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HRP20201595TT HRP20201595T1 (hr) 2011-11-28 2012-11-21 Anti-pd-l1 protutijela i njihova uporaba

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US (4) US9624298B2 (enExample)
EP (2) EP2785375B1 (enExample)
JP (2) JP6138813B2 (enExample)
KR (2) KR101981873B1 (enExample)
CN (1) CN103987405B (enExample)
AR (1) AR089010A1 (enExample)
AU (2) AU2012344260B2 (enExample)
BR (1) BR112014012819B1 (enExample)
CA (1) CA2856895C (enExample)
CY (2) CY1123435T1 (enExample)
DK (1) DK2785375T3 (enExample)
EA (1) EA036814B9 (enExample)
ES (1) ES2808152T3 (enExample)
FR (1) FR20C1068I2 (enExample)
HR (1) HRP20201595T1 (enExample)
HU (2) HUE051954T2 (enExample)
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