ES2633311T3 - Variantes de inmunoglobulina y usos de las mismas - Google Patents

Variantes de inmunoglobulina y usos de las mismas Download PDF

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Publication number
ES2633311T3
ES2633311T3 ES10179942.7T ES10179942T ES2633311T3 ES 2633311 T3 ES2633311 T3 ES 2633311T3 ES 10179942 T ES10179942 T ES 10179942T ES 2633311 T3 ES2633311 T3 ES 2633311T3
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Spain
Prior art keywords
antibody
cells
antigen
antibodies
human
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Expired - Lifetime
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ES10179942.7T
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English (en)
Spanish (es)
Inventor
Camellia W. Adams
Andrew C. Chan
Craig W. Crowley
Henry B. Lowman
Gerald R. Nakamura
Leonard G. Presta
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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