BR9915149A - Tratamento com anticorpo anti-cd20 quimérico de pacientes recebendo transplantes de bmt ou de pbsc - Google Patents
Tratamento com anticorpo anti-cd20 quimérico de pacientes recebendo transplantes de bmt ou de pbscInfo
- Publication number
- BR9915149A BR9915149A BR9915149-9A BR9915149A BR9915149A BR 9915149 A BR9915149 A BR 9915149A BR 9915149 A BR9915149 A BR 9915149A BR 9915149 A BR9915149 A BR 9915149A
- Authority
- BR
- Brazil
- Prior art keywords
- patients receiving
- chimeric anti
- transplants
- antibody treatment
- pbsc
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"TRATAMENTO COM ANTICORPO ANTI-CD20 QUIMéRICO DE PACIENTES RECEBENDO TRANSPLANTES DE BMT OU DE PBSC"<D>. é divulgado o uso de um anticorpo anti-CD20 quimérico, o RITUXAN^ (r)^, como um agente de purgação in vivo ou in vitro, de pacientes recebendo transplante de medula óssea ou de células-tronco de sangue periférico, durante o tratamento de malignidades relacionadas às células B, por exemplo, os linfomas de células B ou as leucemias. Tal purgação pode intensificar a implantação e/ou prevenir a recorrência da doença em tais pacientes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10765798P | 1998-11-09 | 1998-11-09 | |
PCT/US1999/024012 WO2000027433A1 (en) | 1998-11-09 | 1999-11-09 | Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transplants |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9915149A true BR9915149A (pt) | 2001-08-07 |
Family
ID=22317746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9915149-9A BR9915149A (pt) | 1998-11-09 | 1999-11-09 | Tratamento com anticorpo anti-cd20 quimérico de pacientes recebendo transplantes de bmt ou de pbsc |
Country Status (21)
Country | Link |
---|---|
US (5) | US20040213784A1 (pt) |
EP (1) | EP1131096B1 (pt) |
JP (1) | JP2002529429A (pt) |
KR (1) | KR20010099788A (pt) |
CN (1) | CN1330554A (pt) |
AT (1) | ATE454166T1 (pt) |
AU (1) | AU761516B2 (pt) |
BR (1) | BR9915149A (pt) |
CA (1) | CA2350064C (pt) |
CY (1) | CY1110681T1 (pt) |
DE (1) | DE69941903D1 (pt) |
DK (1) | DK1131096T3 (pt) |
ES (1) | ES2338287T3 (pt) |
HK (1) | HK1041811A1 (pt) |
MX (1) | MXPA01004649A (pt) |
MY (1) | MY155913A (pt) |
PT (1) | PT1131096E (pt) |
TR (1) | TR200101302T2 (pt) |
TW (1) | TWI253934B (pt) |
WO (1) | WO2000027433A1 (pt) |
ZA (1) | ZA200103716B (pt) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
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US7744877B2 (en) | 1992-11-13 | 2010-06-29 | Biogen Idec Inc. | Expression and use of anti-CD20 Antibodies |
CA2149329C (en) | 1992-11-13 | 2008-07-15 | Darrell R. Anderson | Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma |
EP1946775A3 (en) | 1998-08-11 | 2008-08-06 | Biogen Idec Inc. | Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody |
WO2000027433A1 (en) * | 1998-11-09 | 2000-05-18 | Idec Pharmaceuticals Corporation | Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transplants |
KR101092132B1 (ko) | 1998-11-09 | 2011-12-12 | 바이오겐 아이덱 인크. | 키메라 항-cd20항체를 이용한 순환성 종양세포와 관련된 혈액학적 악성종양의 치료법 |
US7820161B1 (en) | 1999-05-07 | 2010-10-26 | Biogen Idec, Inc. | Treatment of autoimmune diseases |
US8557244B1 (en) | 1999-08-11 | 2013-10-15 | Biogen Idec Inc. | Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody |
AU2002213357A1 (en) * | 2000-10-20 | 2002-05-06 | Idec Pharmaceuticals Corporation | Variant igg3 rituxan r and therapeutic use thereof |
US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
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EP2330130B1 (en) | 2002-10-17 | 2014-08-27 | Genmab A/S | Human monoclonal antibodies against CD20 |
BRPI0316779B8 (pt) | 2002-12-16 | 2023-02-28 | Genentech Inc | Anticorpo anti-cd20 humano ou fragmento de ligação ao antígeno do mesmo, seus usos, composição, artigo manufaturado e formulação líquida |
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EP2960251A1 (en) * | 2003-05-09 | 2015-12-30 | Duke University | CD20-specific antibodies and methods of employing same |
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US7850962B2 (en) | 2004-04-20 | 2010-12-14 | Genmab A/S | Human monoclonal antibodies against CD20 |
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-
1999
- 1999-11-09 WO PCT/US1999/024012 patent/WO2000027433A1/en not_active Application Discontinuation
- 1999-11-09 ES ES99958649T patent/ES2338287T3/es not_active Expired - Lifetime
- 1999-11-09 KR KR1020017005715A patent/KR20010099788A/ko active Search and Examination
- 1999-11-09 AT AT99958649T patent/ATE454166T1/de active
- 1999-11-09 TR TR2001/01302T patent/TR200101302T2/xx unknown
- 1999-11-09 AU AU15970/00A patent/AU761516B2/en not_active Expired
- 1999-11-09 DK DK99958649.8T patent/DK1131096T3/da active
- 1999-11-09 TW TW088119554A patent/TWI253934B/zh not_active IP Right Cessation
- 1999-11-09 JP JP2000580662A patent/JP2002529429A/ja active Pending
- 1999-11-09 BR BR9915149-9A patent/BR9915149A/pt not_active Application Discontinuation
- 1999-11-09 CA CA2350064A patent/CA2350064C/en not_active Expired - Lifetime
- 1999-11-09 EP EP99958649A patent/EP1131096B1/en not_active Expired - Lifetime
- 1999-11-09 CN CN99814330A patent/CN1330554A/zh active Pending
- 1999-11-09 PT PT99958649T patent/PT1131096E/pt unknown
- 1999-11-09 MY MYPI99004860A patent/MY155913A/en unknown
- 1999-11-09 MX MXPA01004649A patent/MXPA01004649A/es active IP Right Grant
- 1999-11-09 DE DE69941903T patent/DE69941903D1/de not_active Expired - Lifetime
-
2001
- 2001-05-08 ZA ZA200103716A patent/ZA200103716B/en unknown
-
2002
- 2002-05-02 HK HK02103278.5A patent/HK1041811A1/zh unknown
-
2004
- 2004-05-21 US US10/850,712 patent/US20040213784A1/en not_active Abandoned
-
2008
- 2008-04-09 US US12/100,303 patent/US20090074760A1/en not_active Abandoned
-
2010
- 2010-03-18 CY CY20101100247T patent/CY1110681T1/el unknown
-
2011
- 2011-03-18 US US13/051,054 patent/US20110165159A1/en not_active Abandoned
-
2013
- 2013-06-10 US US13/914,421 patent/US20130273041A1/en not_active Abandoned
-
2014
- 2014-01-14 US US14/154,956 patent/US20140363424A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20090074760A1 (en) | 2009-03-19 |
DE69941903D1 (de) | 2010-02-25 |
EP1131096A1 (en) | 2001-09-12 |
ATE454166T1 (de) | 2010-01-15 |
CA2350064C (en) | 2012-05-08 |
KR20010099788A (ko) | 2001-11-09 |
TR200101302T2 (tr) | 2001-10-22 |
ZA200103716B (en) | 2002-08-08 |
EP1131096A4 (en) | 2002-03-20 |
MXPA01004649A (es) | 2002-05-06 |
ES2338287T3 (es) | 2010-05-05 |
DK1131096T3 (da) | 2010-05-17 |
HK1041811A1 (zh) | 2002-07-26 |
CY1110681T1 (el) | 2015-06-10 |
EP1131096B1 (en) | 2010-01-06 |
US20110165159A1 (en) | 2011-07-07 |
AU761516B2 (en) | 2003-06-05 |
CN1330554A (zh) | 2002-01-09 |
TWI253934B (en) | 2006-05-01 |
MY155913A (en) | 2015-12-15 |
US20040213784A1 (en) | 2004-10-28 |
AU1597000A (en) | 2000-05-29 |
CA2350064A1 (en) | 2000-05-18 |
US20140363424A1 (en) | 2014-12-11 |
WO2000027433A1 (en) | 2000-05-18 |
JP2002529429A (ja) | 2002-09-10 |
US20130273041A1 (en) | 2013-10-17 |
PT1131096E (pt) | 2010-04-14 |
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