|
IE52535B1
(en)
*
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
US4637905A
(en)
*
|
1982-03-04 |
1987-01-20 |
Batelle Development Corporation |
Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones
|
|
FR2537980B1
(fr)
*
|
1982-12-17 |
1986-12-19 |
Sandoz Sa |
Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation
|
|
US4652443A
(en)
*
|
1983-06-07 |
1987-03-24 |
Japan Atomic Energy Research Institute |
Slow-release composite and process for producing the same
|
|
CA1196864A
(en)
*
|
1983-06-10 |
1985-11-19 |
Mattheus F.A. Goosen |
Controlled release of injectable and implantable insulin compositions
|
|
CH656884A5
(de)
*
|
1983-08-26 |
1986-07-31 |
Sandoz Ag |
Polyolester, deren herstellung und verwendung.
|
|
CH661206A5
(fr)
*
|
1983-09-23 |
1987-07-15 |
Debiopharm Sa |
Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
|
|
JPS6097918A
(ja)
*
|
1983-11-01 |
1985-05-31 |
Sumitomo Chem Co Ltd |
インタ−フエロン持続性製剤
|
|
JPS60100516A
(ja)
*
|
1983-11-04 |
1985-06-04 |
Takeda Chem Ind Ltd |
徐放型マイクロカプセルの製造法
|
|
JPS60181029A
(ja)
*
|
1984-02-29 |
1985-09-14 |
Toyo Jozo Co Ltd |
徐放性製剤の製法
|
|
GB8416234D0
(en)
*
|
1984-06-26 |
1984-08-01 |
Ici Plc |
Biodegradable amphipathic copolymers
|
|
CA1236641A
(en)
*
|
1984-07-06 |
1988-05-10 |
Motoaki Tanaka |
Copolymer of lactic acid and glycolic acid and method for producing same
|
|
US4666885A
(en)
*
|
1985-02-08 |
1987-05-19 |
Fernand Labrie |
Combination therapy for treatment of female breast cancer
|
|
US4760053A
(en)
*
|
1984-08-02 |
1988-07-26 |
Fernand Labrie |
Combination therapy for selected sex steroid dependent cancers
|
|
US4880635B1
(en)
*
|
1984-08-08 |
1996-07-02 |
Liposome Company |
Dehydrated liposomes
|
|
DE3434345A1
(de)
*
|
1984-09-19 |
1986-03-27 |
Hoechst Ag, 6230 Frankfurt |
Verwendung von (alpha)-interferonen zur bekaempfung von durchfaellen
|
|
DE3678308D1
(de)
*
|
1985-02-07 |
1991-05-02 |
Takeda Chemical Industries Ltd |
Verfahren zur herstellung von mikrokapseln.
|
|
FR2581544B1
(fr)
*
|
1985-05-10 |
1989-11-03 |
Univ Melbourne |
Procede pour provoquer une ovulation chez les juments et vehicule pharmaceutique associe
|
|
US5169633A
(en)
*
|
1985-07-29 |
1992-12-08 |
American Cyanamid Company |
Continuous release phenylethanolamine derivative compositions
|
|
US5137874A
(en)
*
|
1985-07-29 |
1992-08-11 |
American Cyanamid Co. |
Partially coated C10 -C20 fatty acid salts of peptides having molecular weights up to about 5,000
|
|
US5059422A
(en)
*
|
1985-07-29 |
1991-10-22 |
American Cyanamid Company |
Continuous release phenylethanolamine derivative compositions
|
|
US5102872A
(en)
*
|
1985-09-20 |
1992-04-07 |
Cetus Corporation |
Controlled-release formulations of interleukin-2
|
|
US4643191A
(en)
*
|
1985-11-29 |
1987-02-17 |
Ethicon, Inc. |
Crystalline copolymers of p-dioxanone and lactide and surgical devices made therefrom
|
|
JPH0725688B2
(ja)
*
|
1986-03-31 |
1995-03-22 |
住友製薬株式会社 |
Csf徐放性製剤
|
|
GB8609537D0
(en)
*
|
1986-04-18 |
1986-05-21 |
Ici Plc |
Polyesters
|
|
EP0248531A3
(en)
*
|
1986-05-02 |
1988-09-28 |
Southern Research Institute |
Encapsulated nucleic acids
|
|
CA1257199A
(en)
*
|
1986-05-20 |
1989-07-11 |
Paul Y. Wang |
Preparation containing bioactive macromolecular substance for multi-months release in vivo
|
|
US4962091A
(en)
*
|
1986-05-23 |
1990-10-09 |
Syntex (U.S.A.) Inc. |
Controlled release of macromolecular polypeptides
|
|
US6150328A
(en)
|
1986-07-01 |
2000-11-21 |
Genetics Institute, Inc. |
BMP products
|
|
JPH0725689B2
(ja)
*
|
1986-10-07 |
1995-03-22 |
中外製薬株式会社 |
顆粒球コロニ−刺激因子を含有する徐放性製剤
|
|
US5811128A
(en)
*
|
1986-10-24 |
1998-09-22 |
Southern Research Institute |
Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
|
|
US4981696A
(en)
*
|
1986-12-22 |
1991-01-01 |
E. I. Du Pont De Nemours And Company |
Polylactide compositions
|
|
DE3701625A1
(de)
*
|
1987-01-21 |
1988-08-04 |
Boehringer Ingelheim Kg |
Perorale arzneimittelzubereitung mit verzoegerter wirkstofffreigabe
|
|
DE3710175A1
(de)
*
|
1987-02-12 |
1988-08-25 |
Hoechst Ag |
Mehrteilige implantierbare arzneizubereitung mit langzeitwirkung
|
|
AU606383B2
(en)
*
|
1987-03-06 |
1991-02-07 |
Research Triangle Institute |
Polymer blends for selective biodegradability
|
|
US5028430A
(en)
*
|
1987-05-08 |
1991-07-02 |
Syntex (U.S.A.) Inc. |
Delivery systems for the controlled administration of LHRH analogs
|
|
US5000886A
(en)
*
|
1987-05-26 |
1991-03-19 |
American Cyanamid Company |
Silicone-hardened pharmaceutical microcapsules and process of making the same
|
|
GB8716324D0
(en)
*
|
1987-07-10 |
1987-08-19 |
Sandoz Ltd |
Organic compounds
|
|
DE3845000C2
(de)
*
|
1987-07-10 |
1998-11-19 |
Novartis Ag |
Anwendung von Octreotid zur Behandlung von Brustkrebs
|
|
US4866226A
(en)
*
|
1987-07-13 |
1989-09-12 |
Mitsubishi Denki Kabushiki Kaisha |
Multi-phase circuit breaker employing arc extinguishing apparatus
|
|
JPH0613602B2
(ja)
*
|
1987-07-14 |
1994-02-23 |
三井東圧化学株式会社 |
d▲l▼−乳酸−グリコール酸共重合物の製造方法
|
|
US4897268A
(en)
*
|
1987-08-03 |
1990-01-30 |
Southern Research Institute |
Drug delivery system and method of making the same
|
|
US5212154A
(en)
*
|
1987-08-14 |
1993-05-18 |
Akzo N.V. |
Preparation for treating complications in diabetes
|
|
NZ226171A
(en)
*
|
1987-09-18 |
1990-06-26 |
Ethicon Inc |
Gel formulation containing polypeptide growth factor
|
|
US5457093A
(en)
*
|
1987-09-18 |
1995-10-10 |
Ethicon, Inc. |
Gel formulations containing growth factors
|
|
GB2209937B
(en)
*
|
1987-09-21 |
1991-07-03 |
Depiopharm S A |
Water insoluble polypeptides
|
|
US5187150A
(en)
*
|
1987-10-14 |
1993-02-16 |
Debiopharm S.A. |
Polyester-based composition for the controlled release of polypeptide medicinal substances
|
|
JP2670680B2
(ja)
*
|
1988-02-24 |
1997-10-29 |
株式会社ビーエムジー |
生理活性物質含有ポリ乳酸系微小球およびその製造法
|
|
US4902515A
(en)
*
|
1988-04-28 |
1990-02-20 |
E. I. Dupont De Nemours And Company |
Polylactide compositions
|
|
FR2634770B1
(fr)
*
|
1988-07-29 |
1990-10-05 |
Rhone Poulenc Chimie |
Composition polyester erodable contenant de l'iode pour le traitement des eaux
|
|
US5424346A
(en)
*
|
1988-08-08 |
1995-06-13 |
Ecopol, Llc |
Biodegradable replacement of crystal polystyrene
|
|
US5252642A
(en)
*
|
1989-03-01 |
1993-10-12 |
Biopak Technology, Ltd. |
Degradable impact modified polyactic acid
|
|
US5444113A
(en)
*
|
1988-08-08 |
1995-08-22 |
Ecopol, Llc |
End use applications of biodegradable polymers
|
|
US6323307B1
(en)
|
1988-08-08 |
2001-11-27 |
Cargill Dow Polymers, Llc |
Degradation control of environmentally degradable disposable materials
|
|
US5180765A
(en)
*
|
1988-08-08 |
1993-01-19 |
Biopak Technology, Ltd. |
Biodegradable packaging thermoplastics from lactides
|
|
US5216050A
(en)
*
|
1988-08-08 |
1993-06-01 |
Biopak Technology, Ltd. |
Blends of polyactic acid
|
|
US5502158A
(en)
*
|
1988-08-08 |
1996-03-26 |
Ecopol, Llc |
Degradable polymer composition
|
|
US5250584A
(en)
*
|
1988-08-31 |
1993-10-05 |
G-C Dental Industrial Corp. |
Periodontium-regenerative materials
|
|
US5633002A
(en)
*
|
1988-10-04 |
1997-05-27 |
Boehringer Ingelheim Gmbh |
Implantable, biodegradable system for releasing active substance
|
|
US5247013A
(en)
*
|
1989-01-27 |
1993-09-21 |
Mitsui Toatsu Chemicals, Inc. |
Biocompatible polyester and production thereof
|
|
US4990336A
(en)
*
|
1989-02-08 |
1991-02-05 |
Biosearch, Inc. |
Sustained release dosage form
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
IL93693A
(en)
*
|
1989-03-10 |
2000-01-31 |
Endorech Inc |
Pharmaceutical compositions for the treatment of estrogen sensitive diseases
|
|
NZ234227A
(en)
*
|
1989-06-30 |
1991-08-27 |
Smithkline Beecham Corp |
Delayed release dosage form
|
|
PH30995A
(en)
*
|
1989-07-07 |
1997-12-23 |
Novartis Inc |
Sustained release formulations of water soluble peptides.
|
|
US5538739A
(en)
*
|
1989-07-07 |
1996-07-23 |
Sandoz Ltd. |
Sustained release formulations of water soluble peptides
|
|
HU221294B1
(en)
*
|
1989-07-07 |
2002-09-28 |
Novartis Ag |
Process for producing retarde compositions containing the active ingredient in a polymeric carrier
|
|
JP3350048B2
(ja)
*
|
1989-07-07 |
2002-11-25 |
アンドルシェルシュ・インコーポレイテッド |
アンドロゲン関連疾患の治療方法
|
|
WO1991000732A1
(en)
*
|
1989-07-07 |
1991-01-24 |
Endorecherche Inc. |
Androgen derivatives for use in the inhibition of sex steroid activity
|
|
CH679207A5
(no)
*
|
1989-07-28 |
1992-01-15 |
Debiopharm Sa |
|
|
US5439688A
(en)
*
|
1989-07-28 |
1995-08-08 |
Debio Recherche Pharmaceutique S.A. |
Process for preparing a pharmaceutical composition
|
|
US5225205A
(en)
*
|
1989-07-28 |
1993-07-06 |
Debiopharm S.A. |
Pharmaceutical composition in the form of microparticles
|
|
EP0423484B1
(de)
*
|
1989-10-16 |
1993-11-03 |
PCD-Polymere Gesellschaft m.b.H. |
Pressling mit retardierter Wirkstofffreisetzung
|
|
US5126147A
(en)
*
|
1990-02-08 |
1992-06-30 |
Biosearch, Inc. |
Sustained release dosage form
|
|
US6517859B1
(en)
|
1990-05-16 |
2003-02-11 |
Southern Research Institute |
Microcapsules for administration of neuroactive agents
|
|
DE69133136T2
(de)
*
|
1990-05-16 |
2003-06-18 |
Southern Research Institute, Birmingham |
Mikrokapseln mit gesteuerter freigabe sowie deren verwendung zur stimulierung des nervenfaserwachstums
|
|
CA2046830C
(en)
*
|
1990-07-19 |
1999-12-14 |
Patrick P. Deluca |
Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
|
|
IE912365A1
(en)
*
|
1990-07-23 |
1992-01-29 |
Zeneca Ltd |
Continuous release pharmaceutical compositions
|
|
US5620959A
(en)
*
|
1990-07-31 |
1997-04-15 |
Glaxo Wellcome Inc. |
Bombesin antagonists
|
|
GB9016885D0
(en)
*
|
1990-08-01 |
1990-09-12 |
Scras |
Sustained release pharmaceutical compositions
|
|
US6353030B1
(en)
|
1990-08-01 |
2002-03-05 |
Novartis Ag |
Relating to organic compounds
|
|
NZ240214A
(en)
*
|
1990-10-16 |
1993-02-25 |
Takeda Chemical Industries Ltd |
Polymer compositions comprising a polylactic acid and a copolymer of glycolic acid and a hydroxycarboxylic acid; use as carrier for prolonged release pharmaceutical compositions of water soluble drugs
|
|
US5342557A
(en)
*
|
1990-11-27 |
1994-08-30 |
United States Surgical Corporation |
Process for preparing polymer particles
|
|
US7285531B1
(en)
*
|
1991-04-10 |
2007-10-23 |
Acorda Therapeutics, Inc. |
Method for prophylaxis or treatment of a nervous system, pathophysiological condition involving a glial growth factor sensitive cell by administration of a glial growth factor
|
|
US5403595A
(en)
*
|
1991-05-07 |
1995-04-04 |
Dynagen, Inc. |
Controlled, sustained release delivery system for smoking cessation
|
|
US5486362A
(en)
*
|
1991-05-07 |
1996-01-23 |
Dynagen, Inc. |
Controlled, sustained release delivery system for treating drug dependency
|
|
HU222501B1
(hu)
*
|
1991-06-28 |
2003-07-28 |
Endorecherche Inc. |
MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
|
|
ZA924811B
(en)
*
|
1991-06-28 |
1993-12-29 |
Endorecherche Inc |
Controlled release systems and low dose androgens
|
|
CH683149A5
(fr)
*
|
1991-07-22 |
1994-01-31 |
Debio Rech Pharma Sa |
Procédé pour la préparation de microsphères en matériau polymère biodégradable.
|
|
EP0612348B1
(en)
|
1991-11-04 |
2003-04-23 |
Genetics Institute, LLC |
Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
|
|
US5876452A
(en)
*
|
1992-02-14 |
1999-03-02 |
Board Of Regents, University Of Texas System |
Biodegradable implant
|
|
US6013853A
(en)
*
|
1992-02-14 |
2000-01-11 |
The University Of Texas System |
Continuous release polymeric implant carrier
|
|
US5912015A
(en)
*
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
|
WO1993017668A1
(en)
*
|
1992-03-12 |
1993-09-16 |
Alkermes Controlled Therapeutics, Inc. |
Controlled release acth containing microspheres
|
|
US5656297A
(en)
*
|
1992-03-12 |
1997-08-12 |
Alkermes Controlled Therapeutics, Incorporated |
Modulated release from biocompatible polymers
|
|
US5429822A
(en)
*
|
1992-03-13 |
1995-07-04 |
Cambridge Scientific, Inc. |
Biodegradable bursting release system
|
|
US5780051A
(en)
*
|
1992-04-02 |
1998-07-14 |
Dynagen, Inc. |
Methods and articles of manufacture for nicotine cessation and monitoring nicotine use
|
|
AU4258493A
(en)
*
|
1992-05-21 |
1993-12-13 |
Endorecherche Inc. |
Inhibitors of testosterone 5alpha-reductase activity
|
|
GB9211268D0
(en)
*
|
1992-05-28 |
1992-07-15 |
Ici Plc |
Salts of basic peptides with carboxyterminated polyesters
|
|
US5674534A
(en)
*
|
1992-06-11 |
1997-10-07 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
|
US20030035845A1
(en)
*
|
1992-06-11 |
2003-02-20 |
Zale Stephen E. |
Composition for sustained release of non-aggregated erythropoietin
|
|
US5716644A
(en)
*
|
1992-06-11 |
1998-02-10 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
|
JP2651320B2
(ja)
*
|
1992-07-16 |
1997-09-10 |
田辺製薬株式会社 |
徐放性マイクロスフェア製剤の製造方法
|
|
FR2693905B1
(fr)
*
|
1992-07-27 |
1994-09-02 |
Rhone Merieux |
Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
|
|
US5922340A
(en)
*
|
1992-09-10 |
1999-07-13 |
Children's Medical Center Corporation |
High load formulations and methods for providing prolonged local anesthesia
|
|
US5281419A
(en)
*
|
1992-09-28 |
1994-01-25 |
Thomas Jefferson University |
Biodegradable drug delivery system for the prevention and treatment of osteomyelitis
|
|
CA2150803C
(en)
*
|
1992-12-02 |
2006-01-31 |
Henry Auer |
Controlled release growth hormone containing microspheres
|
|
UA61046C2
(en)
|
1992-12-07 |
2003-11-17 |
Takeda Chemical Industries Ltd |
Sustained-release preparation and method for its manufacture
|
|
TW333456B
(en)
*
|
1992-12-07 |
1998-06-11 |
Takeda Pharm Ind Co Ltd |
A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
|
|
US5672659A
(en)
*
|
1993-01-06 |
1997-09-30 |
Kinerton Limited |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
|
RU2185393C2
(ru)
*
|
1993-01-06 |
2002-07-20 |
Кинертон Лимитед |
Сложный полиэфир и конъюгат на его основе
|
|
US5863985A
(en)
*
|
1995-06-29 |
1999-01-26 |
Kinerton Limited |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
|
US6221958B1
(en)
|
1993-01-06 |
2001-04-24 |
Societe De Conseils De Recherches Et D'applications Scientifiques, Sas |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
|
US5456917A
(en)
*
|
1993-04-12 |
1995-10-10 |
Cambridge Scientific, Inc. |
Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
|
|
US5569467A
(en)
*
|
1993-05-15 |
1996-10-29 |
Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) |
Process for the preparation of microballs and microballs thus obtained
|
|
GB9310030D0
(en)
*
|
1993-05-15 |
1993-06-30 |
Scras |
Dry processed particles and process for the preparation of the same
|
|
US6440457B1
(en)
|
1993-05-27 |
2002-08-27 |
Alza Corporation |
Method of administering antidepressant dosage form
|
|
US5635216A
(en)
*
|
1993-12-16 |
1997-06-03 |
Eli Lilly And Company |
Microparticle compositions containing peptides, and methods for the preparation thereof
|
|
JPH08512056A
(ja)
*
|
1993-06-30 |
1996-12-17 |
ジェネンテク・インコーポレイテッド |
リポソームの製造法
|
|
EP0723402B1
(en)
|
1993-08-30 |
2010-08-18 |
Baylor College Of Medicine |
Senescent cell-derived inhibitors of dna synthesis
|
|
US6291206B1
(en)
|
1993-09-17 |
2001-09-18 |
Genetics Institute, Inc. |
BMP receptor proteins
|
|
US5496923A
(en)
*
|
1993-09-20 |
1996-03-05 |
Mitsui Toatsu Chemicals, Inc. |
Purification process of aliphatic polyester
|
|
US6080429A
(en)
*
|
1993-10-25 |
2000-06-27 |
Genentech, Inc. |
Method for drying microspheres
|
|
US5643605A
(en)
*
|
1993-10-25 |
1997-07-01 |
Genentech, Inc. |
Methods and compositions for microencapsulation of adjuvants
|
|
US6913767B1
(en)
|
1993-10-25 |
2005-07-05 |
Genentech, Inc. |
Compositions for microencapsulation of antigens for use as vaccines
|
|
EP0733109B9
(en)
|
1993-12-07 |
2006-07-05 |
Genetics Institute, LLC |
Bmp-12, bmp-13 and tendon-inducing compositions thereof
|
|
US5763416A
(en)
*
|
1994-02-18 |
1998-06-09 |
The Regent Of The University Of Michigan |
Gene transfer into bone cells and tissues
|
|
US5962427A
(en)
*
|
1994-02-18 |
1999-10-05 |
The Regent Of The University Of Michigan |
In vivo gene transfer methods for wound healing
|
|
US6074840A
(en)
|
1994-02-18 |
2000-06-13 |
The Regents Of The University Of Michigan |
Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
|
|
US5942496A
(en)
*
|
1994-02-18 |
1999-08-24 |
The Regent Of The University Of Michigan |
Methods and compositions for multiple gene transfer into bone cells
|
|
US20020193338A1
(en)
*
|
1994-02-18 |
2002-12-19 |
Goldstein Steven A. |
In vivo gene transfer methods for wound healing
|
|
DE4406172C2
(de)
*
|
1994-02-25 |
2003-10-02 |
Sanol Arznei Schwarz Gmbh |
Polyester
|
|
US6551618B2
(en)
*
|
1994-03-15 |
2003-04-22 |
University Of Birmingham |
Compositions and methods for delivery of agents for neuronal regeneration and survival
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
GB9412273D0
(en)
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
US6093697A
(en)
*
|
1994-11-07 |
2000-07-25 |
The University Of Virginia Patent Foundation |
Synthetic insulin mimetic substances
|
|
US5607686A
(en)
*
|
1994-11-22 |
1997-03-04 |
United States Surgical Corporation |
Polymeric composition
|
|
AU4611496A
(en)
*
|
1995-02-28 |
1996-09-18 |
Innapharma, Inc. |
Elcatonin controlled release microsphere formulation for treatment of osteoporosis
|
|
US6479457B2
(en)
*
|
1995-06-06 |
2002-11-12 |
Kinerton Limited |
Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
|
|
US5665702A
(en)
*
|
1995-06-06 |
1997-09-09 |
Biomeasure Incorporated |
Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
|
|
US5599535A
(en)
*
|
1995-06-07 |
1997-02-04 |
Regents Of The University Of California |
Methods for the cyto-protection of the trabecular meshwork
|
|
US5968542A
(en)
*
|
1995-06-07 |
1999-10-19 |
Southern Biosystems, Inc. |
High viscosity liquid controlled delivery system as a device
|
|
US6413536B1
(en)
|
1995-06-07 |
2002-07-02 |
Southern Biosystems, Inc. |
High viscosity liquid controlled delivery system and medical or surgical device
|
|
US5674888A
(en)
*
|
1995-06-07 |
1997-10-07 |
University Of California |
Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
|
|
US7833543B2
(en)
*
|
1995-06-07 |
2010-11-16 |
Durect Corporation |
High viscosity liquid controlled delivery system and medical or surgical device
|
|
US5747058A
(en)
*
|
1995-06-07 |
1998-05-05 |
Southern Biosystems, Inc. |
High viscosity liquid controlled delivery system
|
|
FI970522L
(fi)
|
1995-06-09 |
1997-04-07 |
Euro Celtique Sa |
Koostumukset ja menetelmät pidennetyn paikallisanestesian aikaansaamiseksi
|
|
US5955574A
(en)
|
1995-07-13 |
1999-09-21 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. |
Analogs of parathyroid hormone
|
|
US5925351A
(en)
|
1995-07-21 |
1999-07-20 |
Biogen, Inc. |
Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
|
|
US6020473A
(en)
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
|
DE69611513T2
(de)
*
|
1995-08-29 |
2001-07-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Verfahren zur herstellung von polyhydroxycarbonsäure
|
|
EP0850051A2
(en)
*
|
1995-08-31 |
1998-07-01 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of an agent
|
|
US5942253A
(en)
*
|
1995-10-12 |
1999-08-24 |
Immunex Corporation |
Prolonged release of GM-CSF
|
|
CA2192773C
(en)
|
1995-12-15 |
2008-09-23 |
Hiroaki Okada |
Production of sustained-release preparation for injection
|
|
US5980945A
(en)
*
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
|
EP0823448A4
(en)
*
|
1996-02-23 |
1998-08-12 |
Kyowa Hakko Kogyo Kk |
PROCESS FOR THE PREPARATION OF POLYHYDROXYCARBOXYLIC ACID
|
|
US5747060A
(en)
*
|
1996-03-26 |
1998-05-05 |
Euro-Celtique, S.A. |
Prolonged local anesthesia with colchicine
|
|
IE960308A1
(en)
*
|
1996-04-23 |
1997-11-05 |
Kinerton Ltd |
Sustained release ionic conjugate
|
|
ES2234014T3
(es)
*
|
1996-04-23 |
2005-06-16 |
Ipsen Manufacturing Ireland Limited |
Polimeros polilacticos acidos.
|
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
|
US5766877A
(en)
*
|
1996-05-10 |
1998-06-16 |
Amgen Inc. |
Genes encoding art, an agouti-related transcript
|
|
US5817343A
(en)
*
|
1996-05-14 |
1998-10-06 |
Alkermes, Inc. |
Method for fabricating polymer-based controlled-release devices
|
|
EP0954301A4
(en)
|
1996-06-24 |
2006-03-08 |
Euro Celtique Sa |
SAFE METHODS OF LOCAL ANESTHESIA
|
|
US6046187A
(en)
*
|
1996-09-16 |
2000-04-04 |
Children's Medical Center Corporation |
Formulations and methods for providing prolonged local anesthesia
|
|
US5952455A
(en)
*
|
1996-10-11 |
1999-09-14 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for producing polyhydroxycarboxylic acid
|
|
PT939804E
(pt)
|
1996-10-25 |
2005-11-30 |
Human Genome Sciences Inc |
Neutroquina alfa
|
|
DK0839525T3
(da)
|
1996-10-31 |
2004-11-29 |
Takeda Pharmaceutical |
Præparat med forlænget frigivelse
|
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US6156728A
(en)
|
1996-11-01 |
2000-12-05 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US6919373B1
(en)
|
1996-11-12 |
2005-07-19 |
Alza Corporation |
Methods and devices for providing prolonged drug therapy
|
|
US7390891B1
(en)
|
1996-11-15 |
2008-06-24 |
Amgen Inc. |
Polynucleotides encoding a telomerase component TP2
|
|
US5919656A
(en)
*
|
1996-11-15 |
1999-07-06 |
Amgen Canada Inc. |
Genes encoding telomerase protein 1
|
|
US20020111603A1
(en)
|
1996-12-02 |
2002-08-15 |
Societe De Conseils De Recherches Et D'application |
Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process
|
|
US7138511B1
(en)
|
1997-01-28 |
2006-11-21 |
The Regents Of The University Of California |
Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
|
|
US6475724B1
(en)
|
1997-01-28 |
2002-11-05 |
The Regents Of The University Of California |
Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
|
|
US6171788B1
(en)
|
1997-01-28 |
2001-01-09 |
The Regents Of The University Of California |
Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
|
|
US7235524B2
(en)
*
|
1997-01-31 |
2007-06-26 |
Applied Research System Ars Holding N.V. |
Medicaments for initiating ovulation
|
|
US5945126A
(en)
*
|
1997-02-13 |
1999-08-31 |
Oakwood Laboratories L.L.C. |
Continuous microsphere process
|
|
US6071982A
(en)
*
|
1997-04-18 |
2000-06-06 |
Cambridge Scientific, Inc. |
Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same
|
|
US20060025328A1
(en)
*
|
1997-05-28 |
2006-02-02 |
Burns Patrick J |
Compositions suitable for controlled release of the hormone GnRH and its analogs
|
|
EP1015477B1
(en)
|
1997-05-30 |
2010-11-10 |
Human Genome Sciences, Inc. |
32 Human secreted proteins
|
|
US6867181B1
(en)
|
1997-06-02 |
2005-03-15 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
|
|
US6113947A
(en)
*
|
1997-06-13 |
2000-09-05 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
US6663899B2
(en)
|
1997-06-13 |
2003-12-16 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
KR100367144B1
(ko)
|
1997-07-02 |
2003-01-14 |
유로-셀티크 소시에떼 아노뉨 |
관절과 체강(body space)내에서 연장된 마취
|
|
US6977074B2
(en)
*
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6994851B1
(en)
|
1997-07-10 |
2006-02-07 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6300127B1
(en)
|
1997-07-30 |
2001-10-09 |
Emory University |
Bone mineralization proteins, DNA, vectors, expression systems
|
|
US7923250B2
(en)
|
1997-07-30 |
2011-04-12 |
Warsaw Orthopedic, Inc. |
Methods of expressing LIM mineralization protein in non-osseous cells
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
EP1015488B1
(en)
|
1997-09-17 |
2009-09-09 |
Human Genome Sciences, Inc. |
Interleukin-17 receptor-like protein
|
|
WO1999024061A1
(en)
|
1997-11-07 |
1999-05-20 |
Chiron Corporation |
Method for producing igf-1 sustained-release formulations
|
|
US6372880B1
(en)
|
1997-12-25 |
2002-04-16 |
Mitsui Chemicals, Inc. |
Copolymer and process for preparing the same
|
|
US5906979A
(en)
*
|
1998-01-27 |
1999-05-25 |
Insmed Pharmaceuticals, Inc. |
Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
|
|
EP1051194B9
(en)
|
1998-01-29 |
2003-11-05 |
Kinerton Limited |
Process for making absorbable microparticles
|
|
EP1053020B1
(en)
*
|
1998-01-29 |
2004-03-31 |
Poly-Med Inc. |
Absorbable microparticles
|
|
NZ525914A
(en)
|
1998-03-10 |
2004-03-26 |
Genentech Inc |
Novel polypeptides and nucleic acids encoding the same
|
|
US20030180368A1
(en)
*
|
1998-03-14 |
2003-09-25 |
Cenes Drug Delivery Limited |
Production of microparticles
|
|
ES2389387T3
(es)
|
1998-03-17 |
2012-10-25 |
Genentech, Inc. |
Polipéptidos homólogos de VEGF y de BMP1
|
|
WO1999047538A1
(en)
|
1998-03-19 |
1999-09-23 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
|
AR020650A1
(es)
*
|
1998-08-10 |
2002-05-22 |
Poly Med Inc |
Polimeros fosforilados y conjugados de los mismos
|
|
US20030007991A1
(en)
*
|
1998-09-25 |
2003-01-09 |
Masters David B. |
Devices including protein matrix materials and methods of making and using thereof
|
|
US6344541B1
(en)
|
1998-09-25 |
2002-02-05 |
Amgen Inc. |
DKR polypeptides
|
|
US7662409B2
(en)
*
|
1998-09-25 |
2010-02-16 |
Gel-Del Technologies, Inc. |
Protein matrix materials, devices and methods of making and using thereof
|
|
EA006703B1
(ru)
|
1998-10-09 |
2006-02-24 |
Байоджен Айдек Эмэй Инк. |
СПОСОБ ЛЕЧЕНИЯ ИНДИВИДУУМА, СТРАДАЮЩЕГО ОТ ВЫЗВАННОГО ВИРУСОМ СИСТЕМНОГО ШОКА И/ИЛИ РАССТРОЙСТВА ДЫХАНИЯ, И СПОСОБ ИНДУЦИРОВАНИЯ ПРОТИВОВИРУСНОГО ОТВЕТА У ДАННОГО ИНДИВИДУУМА ПУТЕМ БЛОКАДЫ ПУТИ МЕТАБОЛИЗМА ЛИМФОТОКСИНА-β
|
|
US6270802B1
(en)
|
1998-10-28 |
2001-08-07 |
Oakwood Laboratories L.L.C. |
Method and apparatus for formulating microspheres and microcapsules
|
|
US6565874B1
(en)
*
|
1998-10-28 |
2003-05-20 |
Atrix Laboratories |
Polymeric delivery formulations of leuprolide with improved efficacy
|
|
US6143314A
(en)
*
|
1998-10-28 |
2000-11-07 |
Atrix Laboratories, Inc. |
Controlled release liquid delivery compositions with low initial drug burst
|
|
WO2000025826A1
(en)
*
|
1998-11-02 |
2000-05-11 |
Societe De Conseils De Recherches Et D'applications Scientifiques Sas |
Lactone bearing absorbable polymers
|
|
AUPP785098A0
(en)
|
1998-12-21 |
1999-01-21 |
Victor Chang Cardiac Research Institute, The |
Treatment of heart disease
|
|
US6365173B1
(en)
|
1999-01-14 |
2002-04-02 |
Efrat Biopolymers Ltd. |
Stereocomplex polymeric carriers for drug delivery
|
|
US6303749B1
(en)
|
1999-01-29 |
2001-10-16 |
Amgen Inc. |
Agouti and agouti-related peptide analogs
|
|
US6727224B1
(en)
|
1999-02-01 |
2004-04-27 |
Genetics Institute, Llc. |
Methods and compositions for healing and repair of articular cartilage
|
|
US7435796B1
(en)
|
1999-02-03 |
2008-10-14 |
Amgen Inc. |
Antibodies which bind B7RP1
|
|
US7708993B2
(en)
|
1999-02-03 |
2010-05-04 |
Amgen Inc. |
Polypeptides involved in immune response
|
|
US8624010B1
(en)
|
1999-02-03 |
2014-01-07 |
Steven K. Yoshinaga |
Nucleic acids encoding B7RP1
|
|
PT1149114E
(pt)
|
1999-02-03 |
2014-05-22 |
Amgen Inc |
Polipéptidos envolvidos na resposta imunitária
|
|
AU3501700A
(en)
|
1999-02-26 |
2000-09-14 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
|
EP1156781B1
(en)
|
1999-02-26 |
2005-06-08 |
Chiron Corporation |
Microemulsions with adsorbed macromolecules and microparticles
|
|
JP2002539172A
(ja)
|
1999-03-17 |
2002-11-19 |
ノバルティス アクチエンゲゼルシャフト |
Tgf−ベータを含む医薬組成物
|
|
WO2000058479A1
(en)
|
1999-03-26 |
2000-10-05 |
Amgen Inc. |
Beta secretase genes and polypeptides
|
|
US6635249B1
(en)
|
1999-04-23 |
2003-10-21 |
Cenes Pharmaceuticals, Inc. |
Methods for treating congestive heart failure
|
|
US20030166561A1
(en)
*
|
1999-06-18 |
2003-09-04 |
Cooper Garth J. S. |
Peptide
|
|
MXPA01013236A
(es)
|
1999-06-28 |
2002-06-21 |
Genentech Inc |
Metodos para hacer ligando apo-2 mediante el uso de iones metalicos divalentes.
|
|
US7713739B1
(en)
*
|
2000-11-17 |
2010-05-11 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticle-based transfection and activation of dendritic cells
|
|
US7408047B1
(en)
|
1999-09-07 |
2008-08-05 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7189392B1
(en)
|
1999-10-15 |
2007-03-13 |
Genetics Institute, Llc |
Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
|
|
US7078382B1
(en)
|
1999-11-02 |
2006-07-18 |
Genentech, Inc. |
Modulation of eNOS activity and therapeutic uses thereof
|
|
US6682754B2
(en)
|
1999-11-24 |
2004-01-27 |
Willmar Poultry Company, Inc. |
Ovo delivery of an immunogen containing implant
|
|
US6465425B1
(en)
|
2000-02-10 |
2002-10-15 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
|
|
US20030103978A1
(en)
|
2000-02-23 |
2003-06-05 |
Amgen Inc. |
Selective binding agents of osteoprotegerin binding protein
|
|
WO2001072323A2
(en)
*
|
2000-03-24 |
2001-10-04 |
Genentech, Inc. |
Use of insulin for the treatment of cartilagenous disorders
|
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
|
EP1278767A4
(en)
|
2000-04-12 |
2003-11-12 |
Principia Pharmaceutical Corp |
ALBUMIN FUSED PROTEINS
|
|
HK1053987A1
(zh)
*
|
2000-05-24 |
2003-11-14 |
L. Holtzman Jordan |
提高脑chaperonin水平的物剂及方法
|
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
|
US20040170665A1
(en)
*
|
2000-06-02 |
2004-09-02 |
Allergan, Inc. |
Intravitreal botulinum toxin implant
|
|
US6306423B1
(en)
|
2000-06-02 |
2001-10-23 |
Allergan Sales, Inc. |
Neurotoxin implant
|
|
CA2413160A1
(en)
|
2000-06-15 |
2001-12-20 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
|
EP2168980A1
(en)
|
2000-06-23 |
2010-03-31 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogensis
|
|
EP2275549A1
(en)
|
2000-06-23 |
2011-01-19 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
MXPA02012747A
(es)
|
2000-06-28 |
2003-09-25 |
Amgen Inc |
Moleculas del receptor de linfopoietina estromica timica y sus usos.
|
|
AU2001276733A1
(en)
*
|
2000-08-07 |
2002-02-18 |
Takeda Chemical Industries Ltd. |
Lactic acid polymer and process for producing the same
|
|
US6362308B1
(en)
|
2000-08-10 |
2002-03-26 |
Alkermes Controlled Therapeutics Inc. Ii |
Acid end group poly(d,l-lactide-co-glycolide) copolymers high glycolide content
|
|
US6565888B1
(en)
|
2000-08-23 |
2003-05-20 |
Alkermes Controlled Therapeutics, Inc. |
Methods and compositions for the targeted delivery of biologically active agents
|
|
EP2260867A1
(en)
|
2000-09-14 |
2010-12-15 |
Biogen Idec MA Inc. |
TWEAK receptor agonists as anti-angiogenic agents
|
|
AU2001296770A1
(en)
*
|
2000-10-06 |
2002-04-15 |
Durect Corporation |
Devices and methods for management of inflammation
|
|
DE10055742B4
(de)
|
2000-11-10 |
2006-05-11 |
Schwarz Pharma Ag |
Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen
|
|
US8470359B2
(en)
|
2000-11-13 |
2013-06-25 |
Qlt Usa, Inc. |
Sustained release polymer
|
|
AU2003267309A1
(en)
|
2000-11-16 |
2004-04-08 |
Microspherix Llc |
Flexible and/or elastic brachytherapy seed or strand
|
|
JP4236925B2
(ja)
|
2000-11-28 |
2009-03-11 |
アムジエン・インコーポレーテツド |
免疫応答に関与する新規ポリペプチド
|
|
US6989247B2
(en)
|
2000-11-28 |
2006-01-24 |
Celltech R & D, Inc. |
Compositions and methods for diagnosing or treating psoriasis
|
|
EP1404516A2
(en)
|
2000-12-13 |
2004-04-07 |
Purdue Research Foundation |
Microencapsulation of drugs by solvent exchange
|
|
EP1363602A4
(en)
*
|
2001-01-25 |
2006-01-11 |
Euro Celtique Sa |
LOCAL ANESTHESIA, AND METHOD OF USE
|
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
GB0111628D0
(en)
|
2001-05-11 |
2001-07-04 |
Scancell Ltd |
Binding member
|
|
ATE393573T1
(de)
|
2001-06-01 |
2008-05-15 |
Wyeth Corp |
Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
|
|
AUPR546801A0
(en)
|
2001-06-05 |
2001-06-28 |
Commonwealth Scientific And Industrial Research Organisation |
Recombinant antibodies
|
|
TWI267378B
(en)
|
2001-06-08 |
2006-12-01 |
Wyeth Corp |
Calcium phosphate delivery vehicles for osteoinductive proteins
|
|
JP2004535431A
(ja)
|
2001-06-22 |
2004-11-25 |
サザン バイオシステムズ, インコーポレイテッド |
ゼロ次長期放出同軸インプラント
|
|
ES2675735T3
(es)
|
2001-06-26 |
2018-07-12 |
Amgen Inc. |
Anticuerpos para OPGL
|
|
TWI332407B
(en)
|
2001-06-29 |
2010-11-01 |
Takeda Chemical Industries Ltd |
Controlled release composition and method of producting the same
|
|
WO2003018754A2
(en)
|
2001-08-24 |
2003-03-06 |
Neuronz Limited |
Neural regeneration peptide and methods for their use in treatment of brain damage
|
|
MXPA04001720A
(es)
|
2001-08-29 |
2004-05-31 |
Genentech Inc |
Acido nucleicos bv8 y polipeptidos con actividad mitogenica.
|
|
WO2003018782A2
(en)
*
|
2001-08-30 |
2003-03-06 |
Stem Cell Therapeutics Inc. |
Differentiation of neural stem cells and therapeutic use theeof
|
|
GB0122113D0
(en)
*
|
2001-09-11 |
2001-10-31 |
Astrazeneca Ab |
Composition
|
|
US7393830B2
(en)
*
|
2001-09-14 |
2008-07-01 |
Stem Cell Therapeutics Inc. |
Prolactin induced increase in neural stem cell numbers
|
|
US20030054551A1
(en)
*
|
2001-09-18 |
2003-03-20 |
Stem Cell Therapeutics Inc. |
Effect of growth hormone and IGF-1 on neural stem cells
|
|
NZ532427A
(en)
|
2001-09-24 |
2008-07-31 |
Imp Innovations Ltd |
Modification of feeding behavior using PYY (peptide YY) and its agonists such as NPY (neuropeptide Y)
|
|
EP2348043A1
(en)
|
2001-10-02 |
2011-07-27 |
Genentech, Inc. |
APO-2 ligand variants and uses thereof
|
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
EP2316485A1
(en)
|
2001-10-12 |
2011-05-04 |
Schering Corporation |
Use of bispecific antibodies to regulate immune responses
|
|
EP2322165A1
(en)
|
2001-11-13 |
2011-05-18 |
Genentech, Inc. |
Apo2 ligand/TRAIL formulations
|
|
NZ533434A
(en)
*
|
2001-11-14 |
2006-11-30 |
Alza Corp |
Thixotropic gel composition for injectable deposition
|
|
CU23043A1
(es)
|
2001-12-20 |
2005-05-20 |
Ct Ingenieria Genetica Biotech |
Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico.
|
|
EP2277889B1
(en)
|
2001-12-21 |
2014-07-09 |
Human Genome Sciences, Inc. |
Fusion proteins of albumin and interferon beta
|
|
JP4733922B2
(ja)
|
2002-01-10 |
2011-07-27 |
インペリアル・イノベ−ションズ・リミテッド |
摂食行動の修正
|
|
US8058233B2
(en)
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
US7662924B2
(en)
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
|
WO2003079990A2
(en)
*
|
2002-03-19 |
2003-10-02 |
Purdue Research Foundation |
Microencapsulation using ultrasonic atomizers
|
|
EP1494714A4
(en)
|
2002-04-05 |
2008-03-05 |
Amgen Inc |
HUMAN ANTI-OPGL NEUTRALIZING ANTIBODIES AS SELECTIVE OPGL PATH HEMMER
|
|
JP4386741B2
(ja)
|
2002-04-15 |
2009-12-16 |
中外製薬株式会社 |
scDbライブラリーの作成方法
|
|
EP1505148B1
(en)
|
2002-04-26 |
2009-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of screening for agonistic antibodies
|
|
CA2483778A1
(en)
|
2002-04-29 |
2003-11-13 |
Gel-Del Technologies, Inc. |
Biomatrix structural containment and fixation systems and methods of use thereof
|
|
AU2002304965A1
(en)
|
2002-05-24 |
2003-12-12 |
Zensun (Shanghai) Sci-Tech.Ltd |
Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
|
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
DE10227232A1
(de)
*
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
|
EP2500032A1
(en)
|
2002-06-24 |
2012-09-19 |
Genentech, Inc. |
APO-2 ligand/trail variants and uses thereof
|
|
US20040001889A1
(en)
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
|
US20050232995A1
(en)
|
2002-07-29 |
2005-10-20 |
Yam Nyomi V |
Methods and dosage forms for controlled delivery of paliperidone and risperidone
|
|
EP1546198A1
(en)
*
|
2002-07-31 |
2005-06-29 |
Stem Cell Therapeutics Inc. |
Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
|
|
US20040142393A1
(en)
*
|
2002-08-01 |
2004-07-22 |
Cooper Garth James Smith |
Methods of use of compounds with preptin function
|
|
US8075585B2
(en)
*
|
2002-08-29 |
2011-12-13 |
Stryker Corporation |
Device and method for treatment of a vascular defect
|
|
NZ605429A
(en)
|
2002-09-06 |
2014-08-29 |
Amgen Inc |
Therapeutic human anti-il-1r1 monoclonal antibody
|
|
AU2003285874A1
(en)
|
2002-10-16 |
2004-05-04 |
Amgen Inc. |
HUMAN ANTI-IFN-Gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-Gamma PATHWAY INHIBITORS
|
|
US20040086532A1
(en)
*
|
2002-11-05 |
2004-05-06 |
Allergan, Inc., |
Botulinum toxin formulations for oral administration
|
|
CN1849142A
(zh)
|
2002-11-15 |
2006-10-18 |
埃迪尼克斯(开曼)有限公司 |
2′-支链核苷和黄病毒突变
|
|
RU2377253C2
(ru)
|
2002-12-02 |
2009-12-27 |
Амген Фремонт,Инк. |
Антитела, специфичные к фактору некроза опухолей, и их применение
|
|
AU2003299659A1
(en)
|
2002-12-13 |
2004-07-09 |
Durect Corporation |
Oral drug delivery system comprising high viscosity liquid carrier materials
|
|
US7022481B2
(en)
|
2002-12-19 |
2006-04-04 |
Rosetta Inpharmatics Llc |
Methods of using glucan synthase pathway reporter genes to screen for antifungal compounds
|
|
MXPA05007019A
(es)
|
2002-12-30 |
2005-08-18 |
Amgen Inc |
Terapia de combinacion con factores co-estimuladores.
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
EP1440992A1
(fr)
*
|
2003-01-21 |
2004-07-28 |
Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) |
Système catalytique de (co)polymérisation du lactide et du glycolide
|
|
BRPI0407071B8
(pt)
|
2003-01-28 |
2021-05-25 |
Ironwood Pharmaceuticals Inc |
peptídeo purificado, seu método de produção e composição farmacêutica para o tratamento de distúrbios gastrointestinais
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
GB0304726D0
(en)
*
|
2003-03-01 |
2003-04-02 |
Ardana Bioscience Ltd |
New Process
|
|
WO2005032496A2
(en)
|
2003-03-07 |
2005-04-14 |
Diversa Corporation |
Hydrolases, nucleic acids encoding them and mehods for making and using them
|
|
KR101118340B1
(ko)
|
2003-03-12 |
2012-04-12 |
제넨테크, 인크. |
조혈을 촉진하기 위한 bv8 및(또는) eg-vegf의용도
|
|
JP4489761B2
(ja)
*
|
2003-03-14 |
2010-06-23 |
ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク |
マイクロ流体無膜交換装置を有する血液ベースの治療のためのシステム及び方法
|
|
US20060076295A1
(en)
|
2004-03-15 |
2006-04-13 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
|
|
DK1613750T3
(en)
|
2003-03-19 |
2016-01-18 |
Amgen Fremont Inc |
ANTIBODIES TO T CELL AND MUCINDO immunoglobulin-binding domain 1 (TIM-1) antigen and uses thereof
|
|
US7785829B2
(en)
|
2003-03-19 |
2010-08-31 |
Biogen Idec Ma, Inc. |
Nogo receptor binding protein
|
|
AU2004233851B2
(en)
*
|
2003-04-25 |
2009-07-30 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions comprising cationic microparticles and HCV E1E2 DNA and methods of use thereof
|
|
WO2004103390A2
(en)
|
2003-05-15 |
2004-12-02 |
Trustees Of Tufts College |
Stable analogs of peptide and polypeptide therapeutics
|
|
US7375076B2
(en)
|
2003-05-20 |
2008-05-20 |
The Regents Of The University Of Michigan |
Methods of reducing vascular permeability in tissue by inhibition of tissue plasminogen activator (tPA) and tPA inhibitors useful therein
|
|
US7736644B2
(en)
|
2003-06-27 |
2010-06-15 |
Amgen Fremont Inc. |
Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof
|
|
EP2462923A3
(en)
*
|
2003-07-18 |
2012-08-29 |
Oakwood Laboratories L.L.C. |
Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
|
|
US8609090B2
(en)
|
2003-07-18 |
2013-12-17 |
Amgen Inc. |
Specific binding agents to hepatocyte growth factor
|
|
US8541051B2
(en)
*
|
2003-08-14 |
2013-09-24 |
Halliburton Energy Services, Inc. |
On-the fly coating of acid-releasing degradable material onto a particulate
|
|
WO2005020933A2
(en)
*
|
2003-09-02 |
2005-03-10 |
University Of South Florida |
Nanoparticles for drug-delivery
|
|
GB0320806D0
(en)
*
|
2003-09-05 |
2003-10-08 |
Astrazeneca Ab |
Therapeutic treatment
|
|
ATE357244T1
(de)
|
2003-09-12 |
2007-04-15 |
Wyeth Corp |
Injizierbare feste calciumphosphat-stäbe zur abgabe von osteogenen proteinen
|
|
ES2373783T3
(es)
|
2003-09-12 |
2012-02-08 |
Tercica, Inc. |
Métodos para el tratamiento de la deficiencia de factor 1 de crecimiento similar a la insulina (igf-1).
|
|
US20050080313A1
(en)
*
|
2003-10-10 |
2005-04-14 |
Stewart Daren L. |
Applicator for radiation treatment of a cavity
|
|
US7309232B2
(en)
*
|
2003-10-10 |
2007-12-18 |
Dentigenix Inc. |
Methods for treating dental conditions using tissue scaffolds
|
|
WO2005035753A1
(ja)
|
2003-10-10 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
|
US7783006B2
(en)
*
|
2003-10-10 |
2010-08-24 |
Xoft, Inc. |
Radiation treatment using x-ray source
|
|
EP1693448A4
(en)
|
2003-10-14 |
2008-03-05 |
Chugai Pharmaceutical Co Ltd |
DOUBLE SPECIFICITY ANTIBODY FOR FUNCTIONAL PROTEIN SUBSTITUTION
|
|
CA2543484C
(en)
|
2003-10-27 |
2014-02-04 |
Amgen Inc. |
Modulation of immune response to an immunogen with ctla-4 and tnfbp
|
|
AU2004287875B2
(en)
|
2003-11-05 |
2011-06-02 |
Bausch + Lomb Ireland Limited |
Modulators of cellular adhesion
|
|
EP2286791B1
(en)
|
2003-12-30 |
2014-03-26 |
Durect Corporation |
Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents
|
|
CN100534527C
(zh)
*
|
2003-12-30 |
2009-09-02 |
杜雷科特公司 |
用于控制释放优选为GnRH的活性剂的优选含有PEG和PLG的混合物的聚合植入物
|
|
AU2004313242A1
(en)
*
|
2004-01-07 |
2005-07-28 |
Trimeris, Inc. |
HIV gp41 HR2-derived synthetic peptides, and their use in therapy to inhibit transmission of human immunodeficiency virus
|
|
BRPI0507169A
(pt)
|
2004-02-02 |
2007-06-26 |
Ambrx Inc |
polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
|
|
US20070066525A1
(en)
*
|
2004-02-04 |
2007-03-22 |
Lee John C |
Compositions and therapeutic methods using morphogenic proteins
|
|
JP4990634B2
(ja)
|
2004-02-13 |
2012-08-01 |
ステム セル セラピューティクス コーポレイション |
神経幹細胞の増殖および神経発生のための黄体化ホルモン(LH)、および絨毛性ゴナドトロピン(hCG)の使用
|
|
WO2005090564A1
(ja)
|
2004-03-19 |
2005-09-29 |
Genomidea Inc. |
血管内皮増殖促進遺伝子
|
|
AU2005227313A1
(en)
|
2004-03-19 |
2005-10-06 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through V gene manipulation
|
|
CN1980957A
(zh)
|
2004-03-23 |
2007-06-13 |
比奥根艾迪克Ma公司 |
受体偶联剂及其治疗用途
|
|
GB0410627D0
(en)
|
2004-05-12 |
2004-06-16 |
Scancell Ltd |
Specific binding members
|
|
EP1598428A1
(en)
|
2004-05-18 |
2005-11-23 |
Georg Dewald |
Methods and kits to detect Hereditary angioedema type III
|
|
EP1751115A4
(en)
|
2004-05-23 |
2010-10-20 |
Gerard M Housey |
THERAMUTEINMODULATOREN
|
|
CA2567405A1
(en)
|
2004-05-25 |
2005-12-08 |
Stryker Corporation |
Use of morphogenic proteins for treating cartilage defects
|
|
WO2006009901A2
(en)
|
2004-06-18 |
2006-01-26 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
|
JP4852539B2
(ja)
|
2004-06-22 |
2012-01-11 |
ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ |
腫瘍細胞増殖をFOXM1siRNAによって阻害する方法
|
|
BRPI0512500A
(pt)
|
2004-06-24 |
2008-03-11 |
Biogen Idec Inc |
tratamento ou condições envolvendo desmielinação
|
|
WO2006004774A2
(en)
*
|
2004-06-28 |
2006-01-12 |
Stanford University |
Laulimalide analogues as therapeutic agents
|
|
US20060004185A1
(en)
*
|
2004-07-01 |
2006-01-05 |
Leese Richard A |
Peptide antibiotics and peptide intermediates for their prepartion
|
|
ME00226B
(me)
|
2004-07-15 |
2011-02-10 |
Medarex Llc |
Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
|
|
JP2008507280A
(ja)
|
2004-07-21 |
2008-03-13 |
アンブレツクス・インコーポレイテツド |
非天然コードアミノ酸を用いた生合成ポリペプチド
|
|
WO2006017673A2
(en)
|
2004-08-03 |
2006-02-16 |
Biogen Idec Ma Inc. |
Taj in neuronal function
|
|
US8541028B2
(en)
*
|
2004-08-04 |
2013-09-24 |
Evonik Corporation |
Methods for manufacturing delivery devices and devices thereof
|
|
JP4840939B2
(ja)
|
2004-08-04 |
2011-12-21 |
アムジェン インコーポレイテッド |
Dkk−1に対する抗体
|
|
CN101035512B
(zh)
|
2004-08-12 |
2012-01-18 |
昌达生物科技公司 |
用于生物活性化合物可控制释放递送的药物组合物
|
|
CN101106997A
(zh)
|
2004-08-17 |
2008-01-16 |
约翰·霍普金斯大学 |
Pde5抑制剂组合物及治疗心脏病征候的方法
|
|
EP1802326A2
(en)
*
|
2004-09-09 |
2007-07-04 |
Stryker Corporation |
Methods for treating bone tumors using bone morphogenic proteins
|
|
WO2006033948A2
(en)
*
|
2004-09-17 |
2006-03-30 |
Durect Corporation |
Sustained local anesthetic composition containing preferably a sugar ester such as saib
|
|
CA2583061C
(en)
|
2004-10-06 |
2015-02-17 |
Kwang Guan Tay |
Antibody production method
|
|
FR2876379B1
(fr)
*
|
2004-10-08 |
2008-09-05 |
Isochem Sa |
Procede de polymerisation des o-carboxy anhydrides
|
|
WO2006041048A1
(ja)
|
2004-10-15 |
2006-04-20 |
Mie University |
肝再生・修復制御剤
|
|
ATE492563T1
(de)
|
2004-11-17 |
2011-01-15 |
Amgen Inc |
Vollständige humane monoklonale antikörper gegen il-13
|
|
US7619007B2
(en)
|
2004-11-23 |
2009-11-17 |
Adamas Pharmaceuticals, Inc. |
Method and composition for administering an NMDA receptor antagonist to a subject
|
|
GB0425854D0
(en)
*
|
2004-11-25 |
2004-12-29 |
Astrazeneca Ab |
Therapeutic treatment
|
|
EP1838737B1
(en)
|
2004-12-20 |
2011-04-06 |
Amgen Fremont Inc. |
Binding proteins specific for human matriptase
|
|
EP2284194A1
(en)
|
2004-12-21 |
2011-02-16 |
AstraZeneca AB |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
EP1828224B1
(en)
|
2004-12-22 |
2016-04-06 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
|
|
NZ584597A
(en)
|
2004-12-22 |
2011-09-30 |
Ambrx Inc |
Modified human growth hormone
|
|
CN101163464A
(zh)
*
|
2004-12-23 |
2008-04-16 |
杜雷科特公司 |
优选含有PEG和PLG混合物的控制释放GnRH的聚合物植入物
|
|
EP2351577A1
(en)
*
|
2004-12-29 |
2011-08-03 |
Mannkind Corporation |
Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
|
|
ES2395953T3
(es)
|
2005-01-26 |
2013-02-18 |
Amgen Fremont Inc. |
Anticuerpos frente a interleucina-1 beta
|
|
AU2006244297A1
(en)
*
|
2005-04-06 |
2006-11-16 |
Adamas Pharmaceuticals, Inc. |
Methods and compositions for treatment of CNS disorders
|
|
JP4917024B2
(ja)
|
2005-04-08 |
2012-04-18 |
中外製薬株式会社 |
血液凝固第viii因子の機能代替抗体
|
|
WO2006112737A1
(en)
*
|
2005-04-20 |
2006-10-26 |
Protemix Discovery Limited |
Vesiculins
|
|
WO2006116565A2
(en)
*
|
2005-04-25 |
2006-11-02 |
Amgen Inc. |
Biodegradable peptide sustained release compositions containing porogens
|
|
US7342048B2
(en)
|
2005-04-28 |
2008-03-11 |
Nipro Corporation |
Bioabsorbable pharmaceutical formulation
|
|
US7417072B2
(en)
|
2005-05-12 |
2008-08-26 |
Wisconsin Alumni Research Foundation |
Blockade of Pin1 prevents cytokine production by activated immune cells
|
|
WO2006125119A1
(en)
|
2005-05-17 |
2006-11-23 |
Sarcode Corporation |
Compositions and methods for treatment of eye disorders
|
|
US8431110B2
(en)
|
2005-05-23 |
2013-04-30 |
Hmi Medical Innovations, Llc. |
Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
|
|
JP5068167B2
(ja)
|
2005-06-10 |
2012-11-07 |
中外製薬株式会社 |
メグルミンを含有するタンパク質製剤の安定化剤、およびその利用
|
|
EP3348639A3
(en)
|
2005-06-10 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Sc(fv)2 site-directed mutant
|
|
EP1909831A4
(en)
|
2005-06-14 |
2013-02-20 |
Amgen Inc |
SELF-BUFFING PROTEIN FORMULATIONS
|
|
ES2827247T3
(es)
|
2005-06-21 |
2021-05-20 |
Xoma Us Llc |
Anticuerpos y fragmentos de los mismos que se unen a IL-1beta
|
|
PL1904104T3
(pl)
|
2005-07-08 |
2014-02-28 |
Biogen Ma Inc |
Przeciwciała SP35 i ich zastosowania
|
|
SI1915398T1
(sl)
|
2005-07-18 |
2016-07-29 |
Amgen Inc. |
Humana nevtralizacijska protitelesa proti b7rp1
|
|
US20070027105A1
(en)
|
2005-07-26 |
2007-02-01 |
Alza Corporation |
Peroxide removal from drug delivery vehicle
|
|
US20100004156A1
(en)
|
2005-07-27 |
2010-01-07 |
Shalesh Kaushal |
Small Compounds That Correct Protein Misfolding and Uses Thereof
|
|
KR20080052649A
(ko)
|
2005-09-08 |
2008-06-11 |
트러스티즈 오브 터프츠 칼리지 |
안정화된 glp―1 유사체
|
|
EP1928488A4
(en)
*
|
2005-09-27 |
2009-07-22 |
Stem Cell Therapeutics Corp |
REGULATION OF OLIGODENDROCYTE PRECURSOR CELL PROLIFERATION WITH PROLACTIN
|
|
EP3586846A1
(en)
|
2005-09-29 |
2020-01-01 |
Ipsen Pharma |
Compositions and methods for stimulating gastrointestinal motility
|
|
US8852638B2
(en)
|
2005-09-30 |
2014-10-07 |
Durect Corporation |
Sustained release small molecule drug formulation
|
|
EP1933873A4
(en)
|
2005-10-13 |
2009-12-02 |
Human Genome Sciences Inc |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF PATIENTS WITH POSITIVE DISEASES FOR SELF-ANTIBODIES
|
|
BRPI0617378B8
(pt)
|
2005-10-14 |
2022-09-20 |
Chugai Pharmaceutical Co Ltd |
Uso de um inibidor de il-6 para produzir uma composição farmacêutica para suprimir dano a um ilhota transplantada depois do transplante de ilhota; e aperfeiçoar a viabilidade de uma ilhota em um transplante de ilhota
|
|
BRPI0617664B8
(pt)
|
2005-10-21 |
2021-05-25 |
Chugai Pharmaceutical Co Ltd |
uso de um anticorpo que reconhece a il-6 para a produção de uma composição farmacêutica para tratar o enfarte do miocárdio ou suprimir a remodelagem ventricular esquerda depois do enfarte do miocárdio
|
|
KR20080080109A
(ko)
|
2005-11-04 |
2008-09-02 |
바이오겐 아이덱 엠에이 인코포레이티드 |
도파민성 뉴런의 신경돌기 성장 및 생존의 촉진 방법
|
|
US20070106271A1
(en)
*
|
2005-11-09 |
2007-05-10 |
Searete Llc, A Limited Liability Corporation |
Remote control of substance delivery system
|
|
EP2548583A3
(en)
|
2005-11-10 |
2013-02-27 |
Curagen Corporation |
Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen
|
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
|
US8128934B2
(en)
|
2005-11-14 |
2012-03-06 |
Ribomic, Inc. |
Method for treatment or prevention of disease associated with functional disorder of regulatory T cell
|
|
AR057582A1
(es)
|
2005-11-15 |
2007-12-05 |
Nat Hospital Organization |
Agentes para suprimir la induccion de linfocitos t citotoxicos
|
|
CN106443006A
(zh)
|
2005-11-16 |
2017-02-22 |
Ambrx公司 |
包括非天然氨基酸的方法和组合物
|
|
WO2007061029A1
(ja)
|
2005-11-25 |
2007-05-31 |
Keio University |
前立腺癌治療剤
|
|
US20100003287A1
(en)
|
2005-12-01 |
2010-01-07 |
The Provost, Fellows And Scholars Of The Coll. Of The Holy And Undivided Trinity Of Queen Elizabeth |
Compositions and Methods Relating to Treatment of Cancer and Infectious Diseases
|
|
AU2006320479B2
(en)
|
2005-12-02 |
2012-11-08 |
Biogen Ma Inc. |
Treatment of conditions involving demyelination
|
|
US20070213264A1
(en)
|
2005-12-02 |
2007-09-13 |
Mingdong Zhou |
Neuregulin variants and methods of screening and using thereof
|
|
AU2006322887A1
(en)
|
2005-12-05 |
2007-06-14 |
The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin |
Compositions and methods for modulating an immune response
|
|
US8158588B2
(en)
|
2005-12-05 |
2012-04-17 |
Simon Delagrave |
Loop-variant PDZ domains as biotherapeutics, diagnostics and research reagents
|
|
JP5302007B2
(ja)
|
2005-12-13 |
2013-10-02 |
アストラゼネカ アクチボラグ |
インスリン様増殖因子に特異的な結合タンパク質およびその使用
|
|
AU2005339101B2
(en)
|
2005-12-14 |
2013-01-10 |
Herantis Pharma Plc. |
Novel neurotrophic factor protein and uses thereof
|
|
CN101370519B
(zh)
|
2005-12-15 |
2013-07-24 |
阿斯利康(瑞典)有限公司 |
治疗癌症的促血管生成素-2拮抗剂和VEGF-A、KDR和/或Flt1拮抗剂的组合
|
|
US20070154546A1
(en)
*
|
2005-12-30 |
2007-07-05 |
Zhang Jack Y |
Sustained release pharmaceutical compositions
|
|
EP3363455A1
(en)
|
2005-12-30 |
2018-08-22 |
Zensun (Shanghai) Science & Technology, Co., Ltd. |
Extended release of neuregulin for improved cardiac function
|
|
JPWO2007083644A1
(ja)
|
2006-01-17 |
2009-06-11 |
ディナベック株式会社 |
新規タンパク質発現系
|
|
DK1984009T3
(da)
|
2006-01-18 |
2013-01-28 |
Qps Llc |
Farmaceutiske sammensætninger med forbedret stabilitet
|
|
CA2640423C
(en)
|
2006-01-27 |
2016-03-15 |
Biogen Idec Ma Inc. |
Nogo receptor antagonists
|
|
JP5033643B2
(ja)
|
2006-01-27 |
2012-09-26 |
学校法人慶應義塾 |
脈絡膜血管新生を伴う疾患の治療剤
|
|
US7756524B1
(en)
|
2006-01-31 |
2010-07-13 |
Nextel Communications Inc. |
System and method for partially count-based allocation of vocoder resources
|
|
CU23388B6
(es)
|
2006-01-31 |
2009-07-16 |
Ct Ingenieria Genetica Biotech |
Composición farmacéutica de microesferas para prevenir la amputación del pie diabético
|
|
US20070178138A1
(en)
*
|
2006-02-01 |
2007-08-02 |
Allergan, Inc. |
Biodegradable non-opthalmic implants and related methods
|
|
AR059300A1
(es)
|
2006-02-02 |
2008-03-26 |
Trimeris Inc |
Peptidos inhibidores de la fusion de vih con propiedades biologicas mejoradas
|
|
US20090324574A1
(en)
|
2006-02-02 |
2009-12-31 |
Verenium Corporation |
Esterases and Related Nucleic Acids and Methods
|
|
US8333974B2
(en)
*
|
2006-03-17 |
2012-12-18 |
Stem Cell Therapeutics Corp. |
Continuous dosing regimens for neural stem cell proliferating agents and neural stem cell differentiating agents
|
|
EP1837014A1
(en)
*
|
2006-03-21 |
2007-09-26 |
Hexal Ag |
Subcutaneous implants containing a degradation-resistant polylactide polymer and a LH-RH analogue
|
|
WO2007116962A1
(ja)
|
2006-04-07 |
2007-10-18 |
Osaka University |
筋再生促進剤
|
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
|
CA2652549A1
(en)
|
2006-05-17 |
2007-12-13 |
Stryker Corporation |
Use of a soluble morphogenic protein complex for treating cartilage defects
|
|
AU2007254243B2
(en)
|
2006-05-17 |
2013-06-13 |
Ludwig Institute For Cancer Research |
Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases
|
|
US7403325B2
(en)
*
|
2006-05-19 |
2008-07-22 |
Xerox Corporation |
Electrophoretic display device
|
|
JP2010506599A
(ja)
*
|
2006-05-22 |
2010-03-04 |
ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク |
第1流体と第2流体との間で成分を交換する方法、第1流体から第1成分を清浄する方法、血液の処理方法、流体処理装置、第1流体と第1及び第2成分を含む第2流体との間で成分を交換する装置、第1流体と第2流体との間で成分を交換する装置、血漿から血球を分離する方法
|
|
US20100022457A1
(en)
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
EP2049570B1
(en)
|
2006-06-01 |
2016-08-10 |
President and Fellows of Harvard College |
Purification of a bivalently active antibody using a non-chromatographic method
|
|
ES2429407T3
(es)
|
2006-06-08 |
2013-11-14 |
Chugai Seiyaku Kabushiki Kaisha |
Agente preventivo o remedio para enfermedades inflamatorias
|
|
GB0611405D0
(en)
|
2006-06-09 |
2006-07-19 |
Univ Belfast |
FKBP-L: A novel inhibitor of angiogenesis
|
|
CN101517075A
(zh)
|
2006-07-13 |
2009-08-26 |
中外制药株式会社 |
细胞死亡诱导剂
|
|
EP2046435A4
(en)
*
|
2006-07-13 |
2012-06-27 |
Medtronic Inc |
METHOD AND FORMULATIONS FOR OPTIMAL LOCAL ADMINISTRATION OF CELL THERAPY BY MEANS OF MINIMALLY INVASIVE PROCEDURES
|
|
JP5175729B2
(ja)
|
2006-07-21 |
2013-04-03 |
中外製薬株式会社 |
腎疾患治療剤
|
|
JP5693004B2
(ja)
|
2006-07-28 |
2015-04-01 |
チルドレンズ メモリアル ホスピタル |
ヒト胚性幹細胞の微小環境を使用して腫瘍細胞の悪性度を抑制する方法
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
US9505823B2
(en)
|
2006-08-07 |
2016-11-29 |
TEV A Biopharmaceuticals USA, Inc. |
Albumin-insulin fusion proteins
|
|
CA2663083A1
(en)
|
2006-09-08 |
2008-03-13 |
Ambrx, Inc. |
Modified human plasma polypeptide or fc scaffolds and their uses
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
CA2666934A1
(en)
|
2006-10-20 |
2008-04-24 |
Biogen Idec Ma Inc. |
Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor
|
|
US8338376B2
(en)
|
2006-10-20 |
2012-12-25 |
Biogen Idec Ma Inc. |
Compositions comprising variant LT-B-R-IG fusion proteins
|
|
AU2007325918B2
(en)
|
2006-11-03 |
2013-10-17 |
Durect Corporation |
Transdermal delivery systems comprising bupivacaine
|
|
JP2010509612A
(ja)
|
2006-11-14 |
2010-03-25 |
ジェネンテック インコーポレイテッド |
ニューロン再生の活性調節因子
|
|
EA019661B1
(ru)
|
2006-12-08 |
2014-05-30 |
Лексикон Фармасьютикалз, Инк. |
Моноклональные антитела против angptl3
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
EP2094246B1
(en)
|
2006-12-18 |
2020-04-01 |
Takeda Pharmaceutical Company Limited |
Sustained-release composition and method for producing the same
|
|
WO2008077145A2
(en)
|
2006-12-20 |
2008-06-26 |
Xoma Technology Ltd. |
Treatment of il-1-beta related diseases
|
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
|
NO2740744T3
(no)
|
2007-01-09 |
2018-08-25 |
|
|
|
TWI438208B
(zh)
|
2007-01-23 |
2014-05-21 |
Chugai Pharmaceutical Co Ltd |
抑制慢性排斥反應之藥劑
|
|
CN101631559A
(zh)
|
2007-02-02 |
2010-01-20 |
比奥根艾迪克Ma公司 |
脑信号蛋白6a促进髓鞘形成和少突胶质细胞分化的用途
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
CL2008000719A1
(es)
|
2007-03-12 |
2008-09-05 |
Univ Tokushima Chugai Seiyaku |
Agente terapeutico para cancer resistente a agentes quimioterapeuticos que comprende un anticuerpo que reconoce hla de clase i como ingrediente activo; composicion farmaceutica que comprende dicho anticuerpo; y metodo para tratar cancer resistente a
|
|
CN107501407B
(zh)
|
2007-03-30 |
2022-03-18 |
Ambrx公司 |
经修饰fgf-21多肽和其用途
|
|
CA2682848A1
(en)
*
|
2007-04-03 |
2008-10-16 |
Trimeris, Inc. |
Novel formulations for delivery of antiviral peptide therapeutics
|
|
US20100290982A1
(en)
*
|
2007-04-13 |
2010-11-18 |
University Of North Texas Health Science Center At Fort Worth |
Solid in oil/water emulsion-diffusion-evaporation formulation for preparing curcumin-loaded plga nanoparticles
|
|
BRPI0810899A2
(pt)
|
2007-04-13 |
2014-10-29 |
Univ North Texas |
Formulação de nanopartículas de plga ativadas carregadas com agente ativo para substâncias nano-terapêuticas anticâncer direcionais.
|
|
US20110065673A1
(en)
|
2007-05-11 |
2011-03-17 |
Bizen Chemical Co., Ltd. |
Novel leukotriene receptor agonist
|
|
AU2008254538B2
(en)
|
2007-05-18 |
2013-11-07 |
Durect Corporation |
Improved depot formulations
|
|
CN101801415B
(zh)
|
2007-05-25 |
2015-09-23 |
Rb医药品有限公司 |
利培酮化合物的持续递送制剂
|
|
DK2170930T3
(da)
|
2007-06-04 |
2012-11-05 |
Synergy Pharmaceuticals Inc |
Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
GB0710976D0
(en)
|
2007-06-07 |
2007-07-18 |
Bioalvo |
Am Screening method
|
|
HRP20182146T1
(hr)
*
|
2007-06-14 |
2019-02-08 |
Biogen Ma Inc. |
Formulacije protutijela natalizumab
|
|
AU2008268461B2
(en)
|
2007-06-22 |
2015-04-09 |
Children's Medical Center Corporation |
Methods and uses thereof of prosaposin
|
|
CN101932602B
(zh)
|
2007-06-27 |
2017-05-24 |
新加坡国立大学 |
用于Artemin及相关配体的多肽和多核苷酸,及其使用方法
|
|
JP5424330B2
(ja)
|
2007-07-26 |
2014-02-26 |
国立大学法人大阪大学 |
インターロイキン6受容体阻害剤を有効成分とする眼炎症疾患治療剤
|
|
DE102007036101A1
(de)
*
|
2007-08-01 |
2009-02-05 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue glycolidreiche Copolymere
|
|
TW200916113A
(en)
|
2007-08-08 |
2009-04-16 |
Sod Conseils Rech Applic |
Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
|
|
SG10201500328QA
(en)
|
2007-08-21 |
2015-03-30 |
Amgen Inc |
Human c-fms antigen binding proteins
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
EP2615113A3
(en)
|
2007-08-23 |
2013-11-13 |
Amgen Inc. |
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
|
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
|
US20090156488A1
(en)
|
2007-09-12 |
2009-06-18 |
Zensun (Shanghai) Science & Technology Limited |
Use of neuregulin for organ preservation
|
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
|
EP2040075A1
(en)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Compounds and markers for surface-enhanced raman scattering
|
|
CN101874038A
(zh)
*
|
2007-09-25 |
2010-10-27 |
特里梅里斯公司 |
治疗性抗-hiv肽的合成方法
|
|
EP2207809B1
(en)
|
2007-09-26 |
2013-07-03 |
U3 Pharma GmbH |
Heparin-binding epidermal growth factor-like growth factor antigen binding proteins
|
|
US20110172305A1
(en)
*
|
2007-10-02 |
2011-07-14 |
Ester Fride |
Endocannabinoids for Enhancing Growth and Development in Infants
|
|
WO2009044774A1
(ja)
|
2007-10-02 |
2009-04-09 |
Chugai Seiyaku Kabushiki Kaisha |
インターロイキン6受容体阻害剤を有効成分とする移植片対宿主病治療剤
|
|
WO2009046299A2
(en)
*
|
2007-10-04 |
2009-04-09 |
Boston Scientific Scimed, Inc |
Implantable drug depot for intrathecal drug delivery system for pain management
|
|
CN101873797A
(zh)
|
2007-10-19 |
2010-10-27 |
萨可德公司 |
用于治疗糖尿病性视网膜病的组合物和方法
|
|
WO2009064442A1
(en)
*
|
2007-11-13 |
2009-05-22 |
Brookwood Pharmaceuticals, Inc. |
Viscous terpolymers as drug delivery platform
|
|
DK2207568T3
(en)
|
2007-11-16 |
2017-09-18 |
Univ Rockefeller |
ANTIBODIES SPECIFIC TO THE PROTOFIBRILE FORM OF BETA AMYLOID PROTEIN
|
|
MX338336B
(es)
|
2007-11-20 |
2016-04-07 |
Ambrx Inc |
Polipeptidos de insulina modificados y sus usos.
|
|
KR20160074019A
(ko)
|
2007-12-05 |
2016-06-27 |
추가이 세이야쿠 가부시키가이샤 |
항nr10 항체 및 그의 이용
|
|
US8431127B2
(en)
|
2007-12-05 |
2013-04-30 |
Chugai Seiyaku Kabushiki Kaisha |
Method for treating pruritus comprising administering an NR10 antagonist
|
|
CA2706931C
(en)
|
2007-12-06 |
2015-05-12 |
Durect Corporation |
Oral pharmaceutical dosage forms
|
|
JPWO2009075344A1
(ja)
|
2007-12-12 |
2011-04-28 |
独立行政法人国立がん研究センター |
M−csf受容体を分子標的とするmll白血病及びmoz白血病治療剤、およびその利用
|
|
AU2008343085B2
(en)
|
2007-12-20 |
2015-03-12 |
Xoma (Us) Llc |
Methods for the treatment of gout
|
|
US20090181068A1
(en)
*
|
2008-01-14 |
2009-07-16 |
Dunn Richard L |
Low Viscosity Liquid Polymeric Delivery System
|
|
EP2249899A4
(en)
*
|
2008-02-04 |
2011-05-11 |
Univ Columbia |
FLUID DISTRIBUTION DEVICES, SYSTEMS AND METHODS
|
|
CA2712606A1
(en)
|
2008-02-08 |
2009-08-13 |
Ambrx, Inc. |
Modified leptin polypeptides and their uses
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
WO2009104706A1
(ja)
*
|
2008-02-22 |
2009-08-27 |
東レ株式会社 |
マイクロ粒子およびその医薬品組成物
|
|
US8080562B2
(en)
|
2008-04-15 |
2011-12-20 |
Sarcode Bioscience Inc. |
Crystalline pharmaceutical and methods of preparation and use thereof
|
|
FI20080326A0
(fi)
|
2008-04-30 |
2008-04-30 |
Licentia Oy |
Neurotroofinen tekijä MANF ja sen käytöt
|
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
|
EP2328910B1
(en)
|
2008-06-04 |
2014-08-06 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
CA2728243C
(en)
|
2008-06-05 |
2020-03-10 |
National Cancer Center |
Il-6 inhibitor for suppressing neuroinvasion in pancreatic cancer
|
|
ES2714453T3
(es)
|
2008-06-09 |
2019-05-28 |
Univ Muenchen Ludwig Maximilians |
Fármacos para inhibir la agregación de proteínas implicadas en enfermedades relacionadas con enfermedades neurodegenerativas y/o agregación de proteínas
|
|
EP2307456B1
(en)
|
2008-06-27 |
2014-10-15 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
CA2997870A1
(en)
|
2008-07-09 |
2010-01-14 |
Biogen Ma Inc. |
Compositions comprising antibodies to lingo or fragments thereof
|
|
ES2624828T3
(es)
|
2008-07-16 |
2017-07-17 |
Synergy Pharmaceuticals Inc. |
Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
|
|
UA118536C2
(uk)
|
2008-07-23 |
2019-02-11 |
Амбркс, Інк. |
Модифікований поліпептид бичачого гранулоцитарного колонієстимулювального фактора та його застосування
|
|
EP2907531A1
(en)
|
2008-07-30 |
2015-08-19 |
Mesynthes Limited |
Method of separating or decellularising layers of tissue
|
|
US8153391B2
(en)
|
2008-08-29 |
2012-04-10 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
|
US8198062B2
(en)
|
2008-08-29 |
2012-06-12 |
Dsm Ip Assets B.V. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
|
US8357503B2
(en)
|
2008-08-29 |
2013-01-22 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
|
JP5859307B2
(ja)
|
2008-09-10 |
2016-02-10 |
ジェネンテック, インコーポレイテッド |
眼の血管新生を阻害する方法
|
|
CA2735900A1
(en)
|
2008-09-19 |
2010-03-25 |
Medimmune, Llc |
Antibodies directed to dll4 and uses thereof
|
|
NZ592249A
(en)
|
2008-09-26 |
2013-03-28 |
Ambrx Inc |
Non-natural amino acid replication-dependent microorganisms and vaccines
|
|
HUE035168T2
(en)
|
2008-09-26 |
2018-05-02 |
Ambrx Inc |
Modified animal erythropoietin polypeptides and their applications
|
|
JP5878757B2
(ja)
|
2008-10-10 |
2016-03-08 |
アムジエン・インコーポレーテツド |
Fgf21変異体およびその使用
|
|
WO2010042890A2
(en)
|
2008-10-10 |
2010-04-15 |
Anaphore, Inc. |
Polypeptides that bind trail-ri and trail-r2
|
|
CA2741089A1
(en)
|
2008-10-22 |
2010-04-29 |
Genentech, Inc. |
Modulation of axon degeneration
|
|
BRPI0919979A2
(pt)
|
2008-10-29 |
2015-12-15 |
Wyeth Llc |
formulações de moléculas de ligação de antígeno de domínio único
|
|
US20100260844A1
(en)
|
2008-11-03 |
2010-10-14 |
Scicinski Jan J |
Oral pharmaceutical dosage forms
|
|
US8722052B2
(en)
|
2008-11-17 |
2014-05-13 |
The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin |
Vaccinia virus protein A46 peptide and use thereof
|
|
WO2010062383A2
(en)
|
2008-11-26 |
2010-06-03 |
Amgen Inc. |
Stabilized receptor polypeptides and uses thereof
|
|
EP2382235B1
(en)
|
2008-12-19 |
2016-02-24 |
Christiane Hilger |
Novel caviidae allergen and uses thereof
|
|
WO2010072684A1
(en)
|
2008-12-22 |
2010-07-01 |
Universität Regensburg |
Norrin in the treatment of diseases associated with an increased tgf-beta activity
|
|
AR074874A1
(es)
|
2008-12-23 |
2011-02-16 |
Biosource Pharm Inc |
Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
|
|
US9415197B2
(en)
|
2008-12-23 |
2016-08-16 |
Surmodics, Inc. |
Implantable suction cup composites and implants comprising same
|
|
US20100158978A1
(en)
*
|
2008-12-23 |
2010-06-24 |
Peter Markland |
Bioactive spray coating compositions and methods of making and uses thereof
|
|
US20100168807A1
(en)
*
|
2008-12-23 |
2010-07-01 |
Burton Kevin W |
Bioactive terpolymer compositions and methods of making and using same
|
|
US8974808B2
(en)
*
|
2008-12-23 |
2015-03-10 |
Surmodics, Inc. |
Elastic implantable composites and implants comprising same
|
|
AU2009331528A1
(en)
|
2008-12-23 |
2011-08-11 |
Astrazeneca Ab |
Targeted binding agents directed to alpha5beta1 and uses thereof
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
US8951546B2
(en)
|
2008-12-23 |
2015-02-10 |
Surmodics Pharmaceuticals, Inc. |
Flexible implantable composites and implants comprising same
|
|
US20110294733A1
(en)
|
2009-01-20 |
2011-12-01 |
Hanall Biopharma Co., Ltd. |
Modified human thrombopoietin polypeptide fragment and manufacturing method thereof
|
|
CA2749997A1
(en)
*
|
2009-01-23 |
2010-07-29 |
Surmodics Pharmaceuticals, Inc. |
Polymer mixtures comprising polymers having different non-repeating units and methods for making and using same
|
|
EP2389161A2
(en)
*
|
2009-01-23 |
2011-11-30 |
Surmodics Pharmaceuticals, Inc. |
Controlled release systems from polymer blends
|
|
US20110014190A1
(en)
|
2009-02-12 |
2011-01-20 |
Human Genome Sciences, Inc. |
Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
|
|
JP2012517801A
(ja)
|
2009-02-13 |
2012-08-09 |
ノバルティス アーゲー |
非リボソームペプチドシンターゼをコードする生合成クラスターの核酸分子およびその使用
|
|
TW201031436A
(en)
*
|
2009-02-16 |
2010-09-01 |
Univ Nat Taiwan |
Pharmaceutical composition for inhalation delivery and fabrication method thereof
|
|
WO2010094624A1
(en)
|
2009-02-18 |
2010-08-26 |
Bayer Schering Pharma Aktiengesellschaft |
Particles comprising drospirenone encapsulated in a polymer
|
|
JP2010210772A
(ja)
|
2009-03-13 |
2010-09-24 |
Dainippon Screen Mfg Co Ltd |
液晶表示装置の製造方法
|
|
JP2012525847A
(ja)
|
2009-05-05 |
2012-10-25 |
アムジエン・インコーポレーテツド |
Fgf21変異体およびその使用
|
|
BRPI1011404B1
(pt)
|
2009-05-05 |
2022-05-03 |
Amgen Inc |
Polipeptídeos mutantes fgf21, polipeptídeo de fusão, multímero, composição farmacêutica, ácido nucleico isolado, vetor e célula hospedeira
|
|
EP2260857A1
(en)
|
2009-06-11 |
2010-12-15 |
Alfact Innovation |
Novel applications of HIP/PAP or derivatives thereof
|
|
WO2010144797A2
(en)
|
2009-06-12 |
2010-12-16 |
Vaccine Technologies, Incorporated |
Influenza vaccines with enhanced immunogenicity and uses thereof
|
|
IN2012DN00352A
(no)
|
2009-06-16 |
2015-08-21 |
Bikam Pharmaceuticals Inc |
|
|
US8324160B2
(en)
|
2009-06-17 |
2012-12-04 |
Amgen Inc. |
Chimeric polypeptides and uses thereof
|
|
WO2011010132A1
(en)
|
2009-07-21 |
2011-01-27 |
Astrazeneca Ab |
Sustained-release composition comprising compound 600
|
|
WO2011010131A1
(en)
|
2009-07-21 |
2011-01-27 |
Astrazeneca Ab |
Compositions comprising an oxoisoquinoline methylbenzamide and a polymer
|
|
MY161541A
(en)
|
2009-07-31 |
2017-04-28 |
Shin Maeda |
Cancer metastasis inhibitor
|
|
TW201118166A
(en)
|
2009-09-24 |
2011-06-01 |
Chugai Pharmaceutical Co Ltd |
HLA class I-recognizing antibodies
|
|
EP2305285A1
(en)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Means and methods for treating ischemic conditions
|
|
EP2305810A1
(en)
|
2009-10-02 |
2011-04-06 |
Technische Universität München |
miRNAs in the treatment of fibrosis
|
|
EP2308478A1
(en)
|
2009-10-06 |
2011-04-13 |
Abbott GmbH & Co. KG |
Delivery system for sustained release of a calcium-channel blocking agent
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
CN102711772A
(zh)
|
2009-10-16 |
2012-10-03 |
奥克兰联合服务有限公司 |
Artemin拮抗剂的抗肿瘤用途
|
|
US9068019B2
(en)
|
2009-10-19 |
2015-06-30 |
Hanall Biopharma Co., Ltd. |
Modified human tumor necrosis factor receptor-1 polypeptide or fragment thereof, and method for preparing same
|
|
WO2011050175A1
(en)
|
2009-10-21 |
2011-04-28 |
Sarcode Corporation |
Crystalline pharmaceutical and methods of preparation and use thereof
|
|
RU2012120783A
(ru)
|
2009-10-22 |
2013-11-27 |
Женентек, Инк. |
Модуляция дегенерации аксона
|
|
WO2011056650A2
(en)
|
2009-10-27 |
2011-05-12 |
Michael Zasloff |
Methods and compositions for treating and preventing viral infections
|
|
JP6199033B2
(ja)
|
2009-11-02 |
2017-09-20 |
ユニヴァーシティ オブ ワシントン |
治療用ヌクレアーゼ組成物および方法
|
|
CA2780763A1
(en)
|
2009-11-13 |
2011-05-19 |
Puget Sound Blood Center |
Factor viii b cell epitope variants having reduced immunogenicity
|
|
DK2504364T3
(da)
|
2009-11-24 |
2017-11-06 |
Medimmune Ltd |
Målrettede bindemidler mod b7-h1
|
|
US8623416B2
(en)
|
2009-11-25 |
2014-01-07 |
Michael Zasloff |
Formulations comprising aminosterols
|
|
US8491927B2
(en)
|
2009-12-02 |
2013-07-23 |
Nimble Epitech, Llc |
Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
|
|
EP3132793A1
(en)
|
2009-12-02 |
2017-02-22 |
Adamas Pharmaceuticals, Inc. |
Amantadine compositions and methods of use
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
AU2010339794B2
(en)
|
2009-12-17 |
2016-09-22 |
Children's Medical Center Corporation |
Saposin-A derived peptides and uses thereof
|
|
EA201290541A1
(ru)
|
2009-12-21 |
2013-05-30 |
Амбркс, Инк. |
Модифицированные бычьи соматотропиновые полипептиды и их применение
|
|
EP2516455A4
(en)
|
2009-12-21 |
2013-05-22 |
Ambrx Inc |
MODIFIED SWINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES
|
|
KR20120113265A
(ko)
|
2010-01-15 |
2012-10-12 |
유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 |
골 치료를 촉진시키기 위한 바나듐 화합물의 용도
|
|
EP2525792A1
(en)
|
2010-01-19 |
2012-11-28 |
Medizinische Universität Wien |
Pharmaceutical compositions comprising lignans and their derivatives for the medical management of angiogenesis and hypovascularity
|
|
WO2011094430A2
(en)
|
2010-01-27 |
2011-08-04 |
Children's Medical Center Corporation |
Pro-angiogenic fragments of prominin-1 and uses thereof
|
|
JP2013517782A
(ja)
|
2010-01-28 |
2013-05-20 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
因子vii融合ポリペプチド
|
|
US8778416B2
(en)
|
2010-02-10 |
2014-07-15 |
Nayacure Therapeutics Ltd. |
Pharmaceutical compositions and methods for the treatment and prevention of cancer
|
|
GB201003559D0
(en)
|
2010-03-03 |
2010-04-21 |
Proteo Biotech Ag |
Novel use of elafin
|
|
JP2013525271A
(ja)
|
2010-03-12 |
2013-06-20 |
チルドレンズ メディカル センター コーポレーション |
免疫原およびそのスクリーニング方法
|
|
CN103038255A
(zh)
|
2010-03-26 |
2013-04-10 |
国立大学法人德岛大学 |
新抗cd98抗体及其用途
|
|
MX2012011986A
(es)
|
2010-04-15 |
2013-03-05 |
Amgen Inc |
RECEPTOR FGF HUMANO Y PROTEINAS ENLAZADAS A ß-KLOTHO.
|
|
US20130116304A1
(en)
|
2010-04-19 |
2013-05-09 |
Ernst R. Werner |
Tmem195 encodes for tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity
|
|
US8993572B2
(en)
|
2010-04-22 |
2015-03-31 |
Intra-Cellular Therapies, Inc. |
Pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines derivatives and [1,4]oxazino[2,3,4-hi]pyrido[4,3-b]indole derivatives
|
|
GB201007531D0
(en)
|
2010-05-05 |
2010-06-23 |
Imp Innovations Ltd |
Composition
|
|
US9320756B2
(en)
|
2010-05-07 |
2016-04-26 |
Centre National De La Recherche Scientifique |
UCP1 (thermogenin)—inducing agents for use in the treatment of a disorder of the energy homeostasis
|
|
EP3190187A1
(en)
|
2010-05-21 |
2017-07-12 |
Peptimed, Inc. |
Reagents and methods for treating cancer
|
|
JP5904552B2
(ja)
|
2010-05-28 |
2016-04-13 |
国立研究開発法人国立がん研究センター |
膵癌治療剤
|
|
ES2932398T3
(es)
|
2010-05-28 |
2023-01-18 |
Chugai Pharmaceutical Co Ltd |
Potenciador de la respuesta de las células T antitumorales
|
|
US20130115237A1
(en)
|
2010-06-09 |
2013-05-09 |
Vaccine Technologies, Incorporated |
Therapeutic immunization in hiv infected subjects to augment antiretroviral treatment
|
|
SG186333A1
(en)
|
2010-06-16 |
2013-01-30 |
Endorech Inc |
Methods of treating or preventing estrogen-related diseases
|
|
WO2011157819A2
(en)
|
2010-06-18 |
2011-12-22 |
Xiberscience Gmbh |
Peptides as active agents to stabilize biological barriers
|
|
US8415307B1
(en)
|
2010-06-23 |
2013-04-09 |
Biosource Pharm, Inc. |
Antibiotic compositions for the treatment of gram negative infections
|
|
US9364518B2
(en)
|
2010-06-24 |
2016-06-14 |
Torrent Pharmaceuticals Limited |
Pharmaceutical composition containing goserelin for in-situ implant
|
|
US9211175B2
(en)
|
2010-07-08 |
2015-12-15 |
Covidien Lp |
Self-detachable medical devices
|
|
FR2962646B1
(fr)
|
2010-07-16 |
2012-06-22 |
Sofradim Production |
Prothese avec element radio-opaque
|
|
CA2805572A1
(en)
|
2010-07-16 |
2012-01-19 |
Martin Hegen |
Modified single domain antigen binding molecules and uses thereof
|
|
UY33517A
(es)
|
2010-07-19 |
2012-02-29 |
Astrazeneca Ab |
Depósito farmacéutico para 5-fluoro-2-[[(1S)-1-(5-fluoro-2-piridil)etil]amino]-6-[(5-isopropoxi-1H-pirazol-3-il)amino]piridin-3-carbonitrilo?.
|
|
KR101963460B1
(ko)
|
2010-08-17 |
2019-03-28 |
암브룩스, 인코포레이티드 |
변형된 릴랙신 폴리펩타이드 및 그것의 용도
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
WO2012030822A1
(en)
|
2010-08-30 |
2012-03-08 |
Surmodics Pharmaceuticals, Inc. |
Process for reducing moisture in a biodegradable implant device
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
|
WO2012043533A1
(ja)
|
2010-09-28 |
2012-04-05 |
積水化学工業株式会社 |
抗ヒトccr7抗体、ハイブリドーマ、核酸、ベクター、細胞、医薬組成物、並びに、抗体固定化担体
|
|
US9572907B2
(en)
|
2010-10-01 |
2017-02-21 |
Covidien Lp |
Implantable polymeric films
|
|
MX2013003599A
(es)
|
2010-10-01 |
2013-07-29 |
Biogen Idec Inc |
Interferon-beta para uso como monoterapia o en combinacion con otras terapias de cancer.
|
|
US9861590B2
(en)
|
2010-10-19 |
2018-01-09 |
Covidien Lp |
Self-supporting films for delivery of therapeutic agents
|
|
US8632839B2
(en)
|
2010-10-19 |
2014-01-21 |
Covidien Lp |
Methods of forming self-supporting films for delivery of therapeutic agents
|
|
US8920867B2
(en)
|
2010-10-19 |
2014-12-30 |
Covidien Lp |
Methods of forming self-supporting films for delivery of therapeutic agents
|
|
EP2632481A1
(en)
|
2010-10-25 |
2013-09-04 |
Regents Of The University Of Minnesota |
Therapeutic composition for treatment of glioblastoma
|
|
AU2011319843C1
(en)
|
2010-10-27 |
2017-02-02 |
Amgen Inc. |
DKK1 antibodies and methods of use
|
|
WO2012061443A2
(en)
|
2010-11-01 |
2012-05-10 |
NanoOncology, Inc. |
Compositions of a peptide-based system for cell-specific targeting
|
|
GB201019467D0
(en)
|
2010-11-17 |
2010-12-29 |
Biotecnol Sa |
Therapeutic agent
|
|
TWI629355B
(zh)
|
2010-11-17 |
2018-07-11 |
中外製藥股份有限公司 |
具有替代血液凝固第viii因子之功能的多重專一性抗原結合分子
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
PT2643019T
(pt)
|
2010-11-24 |
2019-04-23 |
Lexicon Pharmaceuticals Inc |
Anticorpos para notum pectinacetilesterase
|
|
TWI736437B
(zh)
|
2010-11-30 |
2021-08-11 |
日商中外製藥股份有限公司 |
細胞傷害誘導治療劑
|
|
JP5819439B2
(ja)
|
2010-12-23 |
2015-11-24 |
ハノル バイオファーマ カンパニー リミテッド |
修飾されたヒト腫瘍壊死因子受容体−1ポリペプチドまたはその断片及びその製造方法
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
US9144634B2
(en)
|
2011-01-14 |
2015-09-29 |
Covidien Lp |
Medical device with intrapore films
|
|
SG10201600531TA
(en)
|
2011-01-24 |
2016-02-26 |
Univ Singapore |
Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
|
|
BR112013018898B1
(pt)
|
2011-01-27 |
2021-10-05 |
Neuren Pharmaceuticals Limited |
Uso de ácido glicil-l-2-metilprolil-l-glutâmico e análogos do mesmo para o tratamento de transtornos do espectro do autismo
|
|
JP2014509588A
(ja)
|
2011-03-01 |
2014-04-21 |
アムジエン・インコーポレーテツド |
二特異性結合剤
|
|
JP2014507483A
(ja)
|
2011-03-10 |
2014-03-27 |
ジェネンテック, インコーポレイテッド |
血管バリヤー機能変化を伴う疾患の治療
|
|
MX356426B
(es)
|
2011-04-04 |
2018-05-29 |
Univ Iowa Res Found |
Metodos para mejorar inmunogenicidad de vacuna.
|
|
SG194111A1
(en)
|
2011-04-07 |
2013-11-29 |
Amgen Inc |
Novel egfr binding proteins
|
|
AU2012240102C1
(en)
|
2011-04-08 |
2016-09-08 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using growth differentiation factor 15 (GDF-15)
|
|
HUE052864T2
(hu)
|
2011-04-25 |
2021-05-28 |
Shan Dong Luye Pharm Co Ltd |
Nyújtott leadású risperidon mikrogömb készítmény
|
|
IL300276B2
(en)
|
2011-04-29 |
2024-11-01 |
Univ Washington |
Therapeutic nuclease compositions and methods
|
|
CA2834776A1
(en)
|
2011-05-03 |
2012-11-08 |
Genentech, Inc. |
Therapeutic apo2l/trail polypeptides and death receptor agonist antibodies
|
|
CA2835018C
(en)
|
2011-05-04 |
2020-04-21 |
Balance Therapeutics, Inc. |
Pentylenetetrazole derivatives
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
US20140189893A1
(en)
|
2011-05-10 |
2014-07-03 |
Amgen Inc. |
Method of identifying compounds that specifically modulate the interaction of fgfr1 and beta klotho
|
|
CA2835630A1
(en)
|
2011-05-11 |
2012-11-15 |
Richard Malley |
Modified biotin-binding protein, fusion proteins thereof and applications
|
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
|
WO2012174064A1
(en)
|
2011-06-14 |
2012-12-20 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
AU2012271329A1
(en)
|
2011-06-17 |
2013-12-19 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using Clec-2
|
|
FR2977790B1
(fr)
|
2011-07-13 |
2013-07-19 |
Sofradim Production |
Prothese pour hernie ombilicale
|
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
US8579924B2
(en)
|
2011-07-26 |
2013-11-12 |
Covidien Lp |
Implantable devices including a mesh and a pivotable film
|
|
WO2013017656A1
(en)
|
2011-08-02 |
2013-02-07 |
Medizinische Universität Wien |
Antagonists of ribonucleases for treating obesity
|
|
CA2843369A1
(en)
|
2011-08-16 |
2013-02-21 |
Evotec (Munchen) Gmbh |
Markers for susceptibility to an inhibitor of an src-family kinase
|
|
WO2013025939A2
(en)
|
2011-08-16 |
2013-02-21 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
|
EP2744828A4
(en)
|
2011-08-16 |
2014-12-31 |
Univ Emory |
JAML-SPECIFIC BINDING AGENTS, ANTIBODIES AND USES THEREOF
|
|
ES2664224T3
(es)
|
2011-08-19 |
2018-04-18 |
Children's Medical Center Corporation |
Proteína de unión a VEGF para el bloqueo de la angiogénesis
|
|
US9782957B2
(en)
|
2011-08-24 |
2017-10-10 |
Covidien Lp |
Medical device films
|
|
CA2845357A1
(en)
|
2011-08-31 |
2013-03-07 |
Amgen Inc. |
Method of treating or ameliorating type 1 diabetes using fgf21
|
|
WO2013039916A1
(en)
|
2011-09-12 |
2013-03-21 |
The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services |
Compositions for and methods of treatment and enhanced detection of non-pituitary tumors
|
|
SG10201800158XA
(en)
|
2011-09-22 |
2018-02-27 |
Amgen Inc |
Cd27l antigen binding proteins
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
US9006400B2
(en)
|
2011-09-26 |
2015-04-14 |
Novartis Ag |
Fibroblast growth factor-21-Fc fusion proteins
|
|
KR102492584B1
(ko)
|
2011-09-30 |
2023-01-27 |
추가이 세이야쿠 가부시키가이샤 |
표적 항원에 대한 면역응답을 유도하는 항원 결합 분자
|
|
DE102011114864A1
(de)
|
2011-10-05 |
2013-04-11 |
Acino Ag |
Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat
|
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun (Shanghai)Science & Technology Limited |
Compositions and methods for treating heart failure
|
|
US8906860B2
(en)
|
2011-10-14 |
2014-12-09 |
The Board Of Trustees Of The University Of Illinois |
Methods and compositions inhibiting tumor cell proliferation
|
|
US20130172265A1
(en)
|
2011-10-14 |
2013-07-04 |
The Board Of Trustees Of The University Of Illinois |
Methods and Compositions for Inhibiting Tumor Cell Proliferation
|
|
EP2768307B1
(en)
|
2011-10-19 |
2020-03-18 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
US8932621B2
(en)
|
2011-10-25 |
2015-01-13 |
Covidien Lp |
Implantable film/mesh composite
|
|
US9005308B2
(en)
|
2011-10-25 |
2015-04-14 |
Covidien Lp |
Implantable film/mesh composite for passage of tissue therebetween
|
|
US9179994B2
(en)
|
2011-10-25 |
2015-11-10 |
Covidien Lp |
Implantable film/mesh composite
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
WO2013075048A1
(en)
|
2011-11-16 |
2013-05-23 |
Amgen Inc. |
Methods of treating epidermal growth factor deletion mutant viii related disorders
|
|
GR1007832B
(el)
|
2011-11-21 |
2013-02-14 |
Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, |
Αδρανοποιητες της ακτιβινης και χρηση τους για την θεραπεια ασθενειων που σχετιζονται με παρεκκλινουσα ενεργοποιηση της "αμυντικης αποκρισης του ξενιστη"
|
|
EP4556010A3
(en)
|
2011-11-30 |
2025-07-23 |
Emory University |
Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
|
|
BR112014012997A2
(pt)
|
2011-11-30 |
2017-06-13 |
Bikam Pharmaceuticals Inc |
ligantes que se ligam à opsina, composições e métodos de uso
|
|
AU2012346537A1
(en)
|
2011-12-01 |
2014-07-17 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
WO2013086443A1
(en)
|
2011-12-08 |
2013-06-13 |
Amgen Inc. |
Agonistic human lcat antigen binding proteins and their use in therapy
|
|
US9376715B2
(en)
|
2011-12-09 |
2016-06-28 |
Roche Molecular Systems, Inc |
Methods for detecting mutations in the catalytic subunit of the phosphoinositol-3 kinase (PIK3CA) gene
|
|
BR112014015003A2
(pt)
|
2011-12-19 |
2019-09-24 |
Amgen Inc |
composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral
|
|
EP2794657B1
(en)
|
2011-12-19 |
2017-10-11 |
Xoma (Us) Llc |
Methods for treating acne
|
|
US10736935B2
(en)
|
2011-12-22 |
2020-08-11 |
Children's Medical Center Corporation |
Saposin-A derived peptides and uses thereof
|
|
EP3663314A1
(en)
|
2012-01-09 |
2020-06-10 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
WO2013106485A2
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
|
JP2015504674A
(ja)
|
2012-01-11 |
2015-02-16 |
アリゾナ ボード オブ リージェンツ ア ボディ コーポレート オブ ザ ステイト オブ アリゾナ アクティング フォー アンド オン ビハーフ オブ アリゾナ ステイト ユニバーシティーArizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
神経疾患タンパク質の二重特異性抗体フラグメントおよび使用方法
|
|
EP2807266B1
(en)
|
2012-01-26 |
2020-01-15 |
Amgen Inc. |
Growth differentiation factor 15 (gdf-15) polypeptides
|
|
EP2626066A1
(en)
|
2012-02-10 |
2013-08-14 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Combination therapy comprising selective VEGFR-2 inhibitors and MEK inhibitors
|
|
WO2013148165A1
(en)
|
2012-03-29 |
2013-10-03 |
The Regents Of The University Of Colorado, A Body Corporate |
Click nucleic acids
|
|
US10206769B2
(en)
|
2012-03-30 |
2019-02-19 |
Covidien Lp |
Implantable devices including a film providing folding characteristics
|
|
US8753643B1
(en)
|
2012-04-11 |
2014-06-17 |
Life-Science Innovations, Llc |
Spray dried compositions and methods of use
|
|
ES2727815T3
(es)
|
2012-04-14 |
2019-10-18 |
Intra Cellular Therapies Inc |
Tratamiento del TEPT y de trastornos del control de impulsos
|
|
CA2871417C
(en)
|
2012-04-23 |
2021-08-31 |
Genefrontier Corporation |
Anti-human cd69 antibody, and use thereof for medical purposes
|
|
EA039663B1
(ru)
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
|
EA030716B1
(ru)
|
2012-05-14 |
2018-09-28 |
Байоджен Ма Инк. |
Антагонисты lingo-2 для лечения заболеваний, в которых участвуют двигательные нейроны
|
|
JO3623B1
(ar)
|
2012-05-18 |
2020-08-27 |
Amgen Inc |
البروتينات المرتبطة بمولد المستضاد st2
|
|
WO2013177187A2
(en)
|
2012-05-22 |
2013-11-28 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-pk il-2 and therapeutic agents
|
|
FR2992662B1
(fr)
|
2012-06-28 |
2014-08-08 |
Sofradim Production |
Tricot avec picots
|
|
FR2992547B1
(fr)
|
2012-06-29 |
2015-04-24 |
Sofradim Production |
Prothese pour hernie
|
|
CA2877441A1
(en)
|
2012-07-02 |
2014-01-09 |
Medizinische Universitat Wien |
Complement split product c4d for the treatment of inflammatory conditions
|
|
EP2687225A1
(en)
|
2012-07-19 |
2014-01-22 |
Alfact Innovation |
HIP/PAP protein and derivatives thereof for use in treating cancer
|
|
EP4406950A3
(en)
|
2012-07-25 |
2025-04-23 |
Bausch + Lomb Ireland Limited |
Lfa-1 inhibitor and polymorph thereof
|
|
DE102013011399A1
(de)
|
2012-07-31 |
2014-02-06 |
Amw Gmbh |
Implantat mit Risperidon
|
|
EP2695950A1
(en)
|
2012-08-10 |
2014-02-12 |
Blackfield AG |
Markers for responsiveness to an inhibitor of the fibroblast growth factor receptor
|
|
CA2881818A1
(en)
|
2012-08-21 |
2014-02-27 |
Genesys Research Institute |
Compositions and methods for treating or preventing anthracycline induced cardiotoxicity
|
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
|
RS58122B1
(sr)
|
2012-10-17 |
2019-02-28 |
Vascular Biogenics Ltd |
Adenovirus koji eksprimira fas-himer i njegova upotreba u postupcima lečenja kancera
|
|
CN108424453B
(zh)
|
2012-11-09 |
2021-08-06 |
基因先端领域株式会社 |
用于治疗癌症的抗adam28抗体
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
MX363188B
(es)
|
2012-11-30 |
2019-03-13 |
Hoffmann La Roche |
Identificación de pacientes con necesidad de coterapia del inhibidor de pd-l1.
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
AU2013361587A1
(en)
|
2012-12-20 |
2015-06-18 |
Medimmune, Llc |
Liquid antibody formulation with improved aggregation properties
|
|
US9920121B2
(en)
|
2013-01-25 |
2018-03-20 |
Amgen Inc. |
Antibodies targeting CDH19 for melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
AU2014212014A1
(en)
|
2013-02-01 |
2015-08-27 |
Amgen Inc. |
Administration of an anti-activin-A compound to a subject
|
|
EP2953638B1
(en)
|
2013-02-07 |
2023-07-05 |
Children's Medical Center Corporation |
Protein antigens that provide protection against pneumococcal colonization and/or disease
|
|
US9545446B2
(en)
|
2013-02-25 |
2017-01-17 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
|
EA033537B1
(ru)
|
2013-03-11 |
2019-10-31 |
Durect Corp |
Инъекционная композиция с контролируемым высвобождением, содержащая жидкий носитель с высокой вязкостью
|
|
US20140308352A1
(en)
|
2013-03-11 |
2014-10-16 |
Zogenix Inc. |
Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
|
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
|
PH12022550138A1
(en)
|
2013-03-13 |
2023-03-06 |
Amgen Inc |
Proteins specific for baff and b7rp1 and uses thereof
|
|
CA2904337A1
(en)
|
2013-03-14 |
2014-10-02 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
|
ES2753950T3
(es)
|
2013-03-15 |
2020-04-15 |
Amgen Res Munich Gmbh |
Moléculas de unión monocatenarias que comprenden ABP del extremo N
|
|
CA2905438A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
|
CA2906737C
(en)
|
2013-03-15 |
2023-08-15 |
Amgen Inc. |
Human pac1 antibodies
|
|
EP2970446A1
(en)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Antibody constructs for influenza m2 and cd3
|
|
US9486494B2
(en)
|
2013-03-15 |
2016-11-08 |
Synergy Pharmaceuticals, Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
US9708375B2
(en)
|
2013-03-15 |
2017-07-18 |
Amgen Inc. |
Inhibitory polypeptides specific to WNT inhibitors
|
|
EP2968480B1
(en)
|
2013-03-15 |
2020-10-14 |
Amgen Inc. |
Treating metabolic disorders using pla2g12a polypeptides and pla2g12a mutant polypeptides
|
|
WO2014144553A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Secreted frizzle-related protein 5 (sfrp5) binding proteins and methods of treatment
|
|
PL2968320T3
(pl)
|
2013-03-15 |
2021-05-17 |
Intra-Cellular Therapies, Inc. |
Związki organiczne
|
|
CN105120659A
(zh)
|
2013-03-15 |
2015-12-02 |
度瑞公司 |
用于降低溶解可变性的具有流变改性剂的组合物
|
|
JP6469644B2
(ja)
|
2013-03-15 |
2019-02-13 |
アムジエン・インコーポレーテツド |
抗ccr7抗原結合タンパク質に関係する方法および組成物
|
|
ES2716384T3
(es)
*
|
2013-04-18 |
2019-06-12 |
Shandong luye pharmaceutical co ltd |
Composición farmacéutica de microesferas de liberación sostenida de goserelina
|
|
US10501803B2
(en)
|
2013-05-21 |
2019-12-10 |
Max-Planck Gesellschaft zur Förderung der Wissenschaften e.V. |
Isoforms of GATA6 and NKX2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy
|
|
RU2015154737A
(ru)
|
2013-05-22 |
2017-06-27 |
Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. |
Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности
|
|
US20160130585A1
(en)
|
2013-05-28 |
2016-05-12 |
The Johns Hopkins University |
Aptamers for the treatment of sickle cell disease
|
|
PL3004167T3
(pl)
|
2013-05-30 |
2019-01-31 |
Kiniksa Pharmaceuticals, Ltd. |
Białka wiążące antygen receptora onkostatyny m
|
|
EP2810648A1
(en)
|
2013-06-04 |
2014-12-10 |
Daniel Rauh |
Targeting domain-domain interaction for the identification of kinase modulators
|
|
EP3009518B1
(en)
|
2013-06-11 |
2020-08-12 |
National Center of Neurology and Psychiatry |
Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (rrms) patient, and method for determining applicability of novel therapy
|
|
JP6869720B2
(ja)
|
2013-06-13 |
2021-05-12 |
アンチセンス セラピューティクス リミテッド |
併用療法
|
|
WO2014204933A1
(en)
|
2013-06-17 |
2014-12-24 |
Adamas Pharmaceuticals, Inc. |
Amantadine compositions and methods of use
|
|
EP2835135A3
(en)
|
2013-06-19 |
2015-06-24 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
Means and methods for treating pseudomonas infection
|
|
WO2014209384A1
(en)
|
2013-06-28 |
2014-12-31 |
Amgen Inc. |
Methods for treating homozygous familial hypercholesterolema
|
|
EP3022224A2
(en)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
CA2918370A1
(en)
|
2013-07-18 |
2015-01-22 |
Fabrus, Inc. |
Humanized antibodies with ultralong complementarity determining regions
|
|
AP2016009011A0
(en)
|
2013-07-31 |
2016-01-31 |
Amgen Inc |
Growth differentiation factor 15 (gdf-15) constructs
|
|
WO2015022326A1
(en)
|
2013-08-12 |
2015-02-19 |
Xiber Science Gmbh |
Peptides as active agents for treating primary graft dysfunction
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
EP3041863A4
(en)
|
2013-09-05 |
2017-08-16 |
Amgen Inc. |
Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
|
|
AU2014318748B2
(en)
|
2013-09-11 |
2019-02-28 |
Duquesne University Of The Holy Ghost |
Novel anthranilic amides and the use thereof
|
|
CA2924109A1
(en)
|
2013-09-13 |
2015-03-19 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
|
TWI688401B
(zh)
|
2013-09-13 |
2020-03-21 |
美商安進公司 |
用於治療骨髓性白血病的表觀遺傳因子與靶向cd33及cd3之雙特異性化合物的組合
|
|
DK2808338T3
(da)
|
2013-09-16 |
2016-06-06 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Mutant calreticulin til diagnose af myeloide maligniteter
|
|
US20160229922A1
(en)
|
2013-09-20 |
2016-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Treatment for hemorrhagic diseases by anti-protein-c antibody
|
|
GB201316738D0
(en)
|
2013-09-20 |
2013-11-06 |
Rainbow Medical Engineering Ltd |
Implantable Medical Devices
|
|
WO2015048331A1
(en)
|
2013-09-25 |
2015-04-02 |
Cornell University |
Compounds for inducing anti-tumor immunity and methods thereof
|
|
US20150104392A1
(en)
|
2013-10-04 |
2015-04-16 |
Aptose Biosciences Inc. |
Compositions, biomarkers and their use in the treatment of cancer
|
|
MY176976A
(en)
|
2013-10-10 |
2020-08-28 |
Bausch Health Ireland Ltd |
Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
|
|
WO2015057852A1
(en)
|
2013-10-15 |
2015-04-23 |
The California Institute For Biomedical Research |
Chimeric antigen receptor t cell switches and uses thereof
|
|
AU2014337367B2
(en)
|
2013-10-15 |
2020-04-30 |
The Scripps Research Institute |
Peptidic chimeric antigen receptor T cell switches and uses thereof
|
|
ES2983249T3
(es)
|
2013-10-15 |
2024-10-22 |
Genefrontier Corp |
Anticuerpo humano frente a especies de ADAMTS de tipo agrecanasa para agentes terapéuticos de enfermedades relacionadas con agrecanasa
|
|
EP3057605A1
(en)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Methods of treating diabetes and related disorders
|
|
JP6495270B2
(ja)
|
2013-10-30 |
2019-04-03 |
ザ ユニバーシティ オブ ウェスタン オーストラリア |
神経保護ペプチドを含有する医薬組成物
|
|
HRP20192080T1
(hr)
|
2013-10-31 |
2020-02-07 |
Resolve Therapeutics, Llc |
Terapeutske fuzije nukleaza-albumine i postupci
|
|
GB201319374D0
(en)
|
2013-11-01 |
2013-12-18 |
Univ Nottingham |
Glycans as functional cancer targets abd antibodies thereto
|
|
AU2014360452C1
(en)
|
2013-12-03 |
2019-05-16 |
Intra-Cellular Therapies, Inc. |
Novel methods
|
|
JP6572497B2
(ja)
|
2013-12-18 |
2019-09-11 |
ザ・スクリップス・リサーチ・インスティテュート |
修飾された治療剤、ステープル留めされたペプチド脂質複合体、及びそれらの組成物
|
|
CN103965357B
(zh)
|
2013-12-31 |
2016-08-17 |
嘉和生物药业有限公司 |
一种抗人rankl抗体
|
|
WO2015110930A1
(en)
|
2014-01-24 |
2015-07-30 |
Pfizer Inc. |
Modified interleukin 21 receptor proteins
|
|
WO2015120187A1
(en)
|
2014-02-05 |
2015-08-13 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants
|
|
US10532083B2
(en)
|
2014-02-13 |
2020-01-14 |
Technische Universität München |
Methods for inducing differentiation or conversion of white adipocytes and/or preadipocytes to brown adipocites using FGF8
|
|
CA2939626C
(en)
|
2014-02-20 |
2023-01-17 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
SG10202104175YA
(en)
|
2014-02-27 |
2021-06-29 |
Allergan Inc |
COMPLEMENT FACTOR Bb ANTIBODIES
|
|
CA2941716A1
(en)
|
2014-03-07 |
2015-09-11 |
The Johns Hopkins University |
Inhibitors of histone lysine specific demethylase (lsd1) and histone deacetylases (hdacs)
|
|
US10472334B2
(en)
|
2014-03-14 |
2019-11-12 |
The University Of North Carolina At Chapel Hill |
Small molecules for inhibiting male fertility
|
|
JP6712952B2
(ja)
|
2014-03-31 |
2020-06-24 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
固形腫瘍悪性病変を処置するための、抗ctla−4抗体および/または抗pd−1抗体と組み合わせた、細菌、細菌産物、および他の免疫調節性実体の使用
|
|
WO2015154030A1
(en)
|
2014-04-04 |
2015-10-08 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
|
KR20170012210A
(ko)
|
2014-04-04 |
2017-02-02 |
인트라-셀룰라 써래피스, 인코퍼레이티드. |
유기 화합물
|
|
US10507227B2
(en)
|
2014-04-15 |
2019-12-17 |
The Hospital For Sick Children |
Cationic antimicrobial peptides
|
|
EP3131532A1
(de)
|
2014-04-16 |
2017-02-22 |
Veyx-Pharma GmbH |
Veterinärpharmazeutische zusammensetzung und deren verwendung
|
|
US20170073690A1
(en)
|
2014-05-15 |
2017-03-16 |
CEMM - Forschungzentrum Fuer Molekulare Medizin GMBH |
Antagonists of slc38a9 and their use in therapy
|
|
US20170119851A1
(en)
|
2014-05-19 |
2017-05-04 |
Novartis Ag |
Methods of treating anorexia
|
|
WO2015184260A2
(en)
|
2014-05-30 |
2015-12-03 |
The Johns Hopkins University |
Methods for treating mendelian disorders of the epigenetic machinery
|
|
MY191346A
(en)
|
2014-06-03 |
2022-06-17 |
Xbiotech Inc |
Compositions and methods for treating and preventing staphylococcus aureus infections
|
|
WO2015191554A1
(en)
|
2014-06-09 |
2015-12-17 |
Intra-Cellular Therapies, Inc. |
Compounds and methods of use to treat schizophrenia
|
|
BR112016028567A2
(pt)
|
2014-06-09 |
2018-01-30 |
Kyowa Hakko Kirin Co Ltd |
método para utilizar ligante anti-fgf23 e para tratar doença e/ou condição relacionada com fgf23 e para aumentar a remodelação óssea
|
|
EA201692568A1
(ru)
|
2014-06-13 |
2017-05-31 |
Санта Мария Биотерапевтикс, Инк. |
Составы с полипептидами-рецепторами и связанные с ними способы
|
|
TWI831106B
(zh)
|
2014-06-20 |
2024-02-01 |
日商中外製藥股份有限公司 |
用於因第viii凝血因子及/或活化的第viii凝血因子的活性降低或欠缺而發病及/或進展的疾病之預防及/或治療之醫藥組成物
|
|
WO2016007919A2
(en)
|
2014-07-11 |
2016-01-14 |
Regents Of The University Of Minnesota |
Antibody fragments for detecting cancer and methods of use
|
|
EP2977758A1
(en)
|
2014-07-24 |
2016-01-27 |
Université De Nice Sophia Antipolis |
Methods and kits for monitoring membranous nephropathy
|
|
EP3174901B1
(en)
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Optimized cross-species specific bispecific single chain antibody constructs
|
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
JP6800141B2
(ja)
|
2014-08-12 |
2020-12-16 |
マサチューセッツ インスティテュート オブ テクノロジー |
Il−2およびインテグリン結合性fc融合タンパク質による相乗的な腫瘍処置
|
|
US20170216403A1
(en)
|
2014-08-12 |
2017-08-03 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
|
CA2958879A1
(en)
|
2014-08-22 |
2016-02-25 |
Auckland Uniservices Limited |
Channel modulators
|
|
SG11201701402QA
(en)
|
2014-08-27 |
2017-03-30 |
Peptimed Inc |
Anti-tumor compositions and methods
|
|
WO2016040767A2
(en)
|
2014-09-12 |
2016-03-17 |
Amgen Inc. |
Chrdl-1 epitopes and antibodies
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
TWI749433B
(zh)
|
2014-10-21 |
2021-12-11 |
開曼群島商賽生製藥國際有限公司 |
用免疫刺激物治療癌症
|
|
HUE055311T2
(hu)
|
2014-10-24 |
2021-11-29 |
Bristol Myers Squibb Co |
Módosított FGF-21 polipeptidek és azok felhasználása
|
|
WO2016069889A1
(en)
|
2014-10-31 |
2016-05-06 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-transferrin fusions and methods
|
|
WO2016079321A1
(en)
|
2014-11-20 |
2016-05-26 |
Cemm Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of setdb2 for use in the therapy of infectious diseases
|
|
EP3085709B1
(en)
|
2014-12-28 |
2019-08-21 |
Genor Biopharma Co., Ltd |
Humanized anti-human rankl antibody, pharmaceutical composition and use thereof
|
|
JP2018504400A
(ja)
|
2015-01-08 |
2018-02-15 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
Lingo‐1拮抗薬及び脱髄障害の治療のための使用
|
|
JP6912386B2
(ja)
|
2015-01-26 |
2021-08-04 |
ザ ユニバーシティー オブ シカゴ |
癌特異的なIL13Rα2を認識するCAR T細胞
|
|
HK1245287A1
(zh)
|
2015-01-26 |
2018-08-24 |
The University Of Chicago |
IL13RAα2结合剂和其在癌症治疗中的用途
|
|
US9375478B1
(en)
|
2015-01-30 |
2016-06-28 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
|
US10906948B2
(en)
|
2015-02-23 |
2021-02-02 |
Seagull Therapeutics Sas |
Non-natural Semaphorins 3 and their medical use
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
MX2017012966A
(es)
|
2015-04-10 |
2018-06-06 |
Amgen Inc |
Muteinas de interleuquina 2 para la expansion de celulas t regulatorias.
|
|
WO2016164937A2
(en)
|
2015-04-10 |
2016-10-13 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
WO2016168773A2
(en)
|
2015-04-15 |
2016-10-20 |
The California Institute For Biomedical Research |
Optimized pne-based chimeric receptor t cell switches and uses thereof
|
|
JP6907124B2
(ja)
|
2015-04-17 |
2021-07-21 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH |
Cdh3及びcd3に対する二重特異性抗体構築物
|
|
WO2016186977A1
(en)
|
2015-05-15 |
2016-11-24 |
The Johns Hopkins University |
Novel fluoride prenatal dietary supplement
|
|
US20160361380A1
(en)
|
2015-06-12 |
2016-12-15 |
Nymox Corporation |
Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations
|
|
US20190000928A1
(en)
|
2015-06-17 |
2019-01-03 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
|
WO2017007955A1
(en)
|
2015-07-07 |
2017-01-12 |
The Research Foundation For The State University Of New York |
Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
|
|
ES2546566B2
(es)
*
|
2015-07-23 |
2016-09-14 |
Universidade De Santiago De Compostela |
Sistema para la administración de sustancias biológicamente activas preparado por técnicas de espumado empleando gases comprimidos o fluidos supercríticos
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
CN108135875B
(zh)
|
2015-07-31 |
2021-12-31 |
约翰霍普金斯大学 |
用于治疗代谢重编程病症的方法和组合物
|
|
CA2994162A1
(en)
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Glutamine antagonists for the treatment of cognitive deficits
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
KR102666477B1
(ko)
|
2015-07-31 |
2024-05-17 |
더 존스 홉킨스 유니버시티 |
글루타민 유사체의 프로드럭
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
US10842763B2
(en)
|
2015-07-31 |
2020-11-24 |
The Johns Hopkins University |
Methods for cancer and immunotherapy using prodrugs of glutamine analogs
|
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
|
JP2018529729A
(ja)
|
2015-10-01 |
2018-10-11 |
アムジエン・インコーポレーテツド |
胆汁酸障害の処置
|
|
JP2019503985A
(ja)
|
2015-11-03 |
2019-02-14 |
グリコミメティクス, インコーポレイテッド |
モノクローナル抗体、造血幹細胞の産生のための方法および組成物、ならびにそれらを使用する方法
|
|
CA3004048A1
(en)
|
2015-11-03 |
2017-05-11 |
Regents Of The University Of Minnesota |
Cd200 inhibitors and methods of use thereof
|
|
CA3002573A1
(en)
|
2015-11-03 |
2017-05-11 |
Ambrx, Inc. |
Anti-cd3 antibodies and their uses
|
|
WO2017086419A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
|
WO2017096262A1
(en)
|
2015-12-04 |
2017-06-08 |
Jomoco, Corp. |
Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
|
|
CN108778320A
(zh)
|
2015-12-18 |
2018-11-09 |
泰伦基国际有限公司 |
一种预防和治疗心血管病的新方法
|
|
MY197023A
(en)
|
2015-12-23 |
2023-05-22 |
Amgen Inc |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
|
JP6954842B2
(ja)
|
2015-12-25 |
2021-10-27 |
中外製薬株式会社 |
増強された活性を有する抗体及びその改変方法
|
|
JP2019506383A
(ja)
|
2016-01-11 |
2019-03-07 |
シナジー ファーマシューティカルズ インコーポレイテッド |
潰瘍性大腸炎を治療するための製剤および方法
|
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
IL309536B2
(en)
|
2016-01-26 |
2025-07-01 |
Intra Cellular Therapies Inc |
Pharmaceutical preparation for injection containing (Sa10, Rb6)-3-)8-(4-fluorophenoxy)propyl)-b6, 7, 8, 9, 10, 10a- hexahydro-H1- pyrido[3',4' :4,5]pyrrolo[1,2,3 -de]quinoxalin-2(H3)-one
|
|
WO2017134158A1
(en)
|
2016-02-03 |
2017-08-10 |
Amgen Research (Munich) Gmbh |
Psma and cd3 bispecific t cell engaging antibody constructs
|
|
KR102688969B1
(ko)
|
2016-02-03 |
2024-07-30 |
암젠 리서치 (뮌헨) 게엠베하 |
Bcma 및 cd3 이중특이성 t 세포 맞물림 항체 작제물
|
|
US10098909B2
(en)
|
2016-02-05 |
2018-10-16 |
University Of South Florida |
Ionic cocrystal of lithium, lispro, for the treatment of fragile X syndrome
|
|
CA3013904C
(en)
|
2016-02-10 |
2023-12-12 |
Rutgers, The State University Of New Jersey |
Novel anti-lam and anti-pim6/lam monoclonal antibodies for diagnosis and treatment of mycobacterium tuberculosis infections
|
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
|
RU2746754C2
(ru)
|
2016-03-14 |
2021-04-20 |
Чугаи Сейяку Кабусики Кайся |
Индуцирующее повреждение клеток терапевтическое лекарственное средство, предназначенное для противораковой терапии
|
|
US10688097B2
(en)
|
2016-03-25 |
2020-06-23 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
|
EP3436083A4
(en)
|
2016-03-28 |
2019-11-27 |
Intra-Cellular Therapies, Inc. |
NOVEL COMPOSITIONS AND METHOD
|
|
US10183058B2
(en)
|
2016-06-17 |
2019-01-22 |
Nymox Corporation |
Method of preventing or reducing the progression of prostate cancer
|
|
AU2017290389B2
(en)
|
2016-07-01 |
2024-09-26 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
|
AU2017292791B2
(en)
|
2016-07-06 |
2023-05-25 |
Orient Pharma Co., Ltd. |
Oral dosage form with drug composition, barrier layer and drug layer
|
|
WO2018013924A1
(en)
|
2016-07-15 |
2018-01-18 |
Massachusetts Institute Of Technology |
Synthetic nanoparticles for delivery of immunomodulatory compounds
|
|
US10172910B2
(en)
|
2016-07-28 |
2019-01-08 |
Nymox Corporation |
Method of preventing or reducing the incidence of acute urinary retention
|
|
AU2017310412A1
(en)
|
2016-08-08 |
2019-02-21 |
Amgen Inc. |
Method of improving connective tissue attachment using anti-sclerostin antibodies
|
|
WO2018044970A1
(en)
|
2016-08-31 |
2018-03-08 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
|
|
RU2766233C2
(ru)
|
2016-09-06 |
2022-02-10 |
Чугаи Сейяку Кабусики Кайся |
Способы применения биспецифического антитела, которое распознает фактор свертывания ix и/или активированный фактор свертывания ix и фактор свертывания x и/или активированный фактор свертывания x
|
|
US10532081B2
(en)
|
2016-09-07 |
2020-01-14 |
Nymox Corporation |
Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
|
|
WO2018053222A1
(en)
|
2016-09-16 |
2018-03-22 |
Research Traingle Institute |
Tetrahydroisoquinoline kappa opioid antagonists
|
|
JP7013454B2
(ja)
|
2016-10-12 |
2022-02-15 |
イントラ-セルラー・セラピーズ・インコーポレイテッド |
アモルファス固体分散体
|
|
KR102613430B1
(ko)
|
2016-10-19 |
2023-12-18 |
더 스크립스 리서치 인스티튜트 |
인간화된 표적화 모이어티 및/또는 최적화된 키메라 항원 수용체-상호작용 도메인을 갖는 키메라 항원 수용체 효과기 세포 스위치 및 이의 용도
|
|
JP7242057B2
(ja)
|
2016-12-15 |
2023-03-20 |
タレンゲン インターナショナル リミテッド |
薬物性腎損傷を予防及び治療するための方法
|
|
CA3047175A1
(en)
|
2016-12-15 |
2018-06-21 |
Talengen International Limited |
Method for mitigating heart disease
|
|
CA3047176C
(en)
|
2016-12-15 |
2021-11-30 |
Talengen International Limited |
Use of plasminogen for promoting secretion of insulin in treatment of diabetes
|
|
US11207387B2
(en)
|
2016-12-15 |
2021-12-28 |
Talengen International Limited |
Method and drug for preventing and treating obesity
|
|
TWI750189B
(zh)
|
2016-12-15 |
2021-12-21 |
大陸商深圳瑞健生命科學研究院有限公司 |
一種治療冠狀動脈粥樣硬化及其併發症的方法
|
|
TWI734798B
(zh)
|
2016-12-15 |
2021-08-01 |
大陸商深圳瑞健生命科學研究院有限公司 |
一種預防和治療肺纖維化的方法
|
|
TW201828976A
(zh)
|
2016-12-15 |
2018-08-16 |
大陸商深圳瑞健生命科學硏究院有限公司 |
纖溶酶原在製備預防和治療骨質疏鬆及其相關病症的藥物中的用途和包含纖溶酶原用於預防或治療骨質疏鬆的藥劑
|
|
US10906906B2
(en)
|
2016-12-29 |
2021-02-02 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
|
US10961245B2
(en)
|
2016-12-29 |
2021-03-30 |
Intra-Cellular Therapies, Inc. |
Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
|
|
CA3049110A1
(en)
|
2017-01-06 |
2018-07-12 |
Abl Bio Inc. |
Anti-.alpha.-syn antibody and use thereof
|
|
US12049493B2
(en)
|
2017-01-06 |
2024-07-30 |
Abl Bio Inc. |
Anti-alpha-synuclein antibodies and uses thereof
|
|
WO2018129470A1
(en)
|
2017-01-09 |
2018-07-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Reversing deficient hedgehog signaling restores deficient skeletal regeneration
|
|
CA3049656A1
(en)
|
2017-01-10 |
2018-07-19 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-fc fusion protein and immune modulator
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
US20190328792A1
(en)
|
2017-01-11 |
2019-10-31 |
Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung |
Mesenchymal stem cell-derived extracellular vesicles and their medical use
|
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
|
AU2018219283B2
(en)
|
2017-02-08 |
2022-05-19 |
Bristol-Myers Squibb Company |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
|
US10335453B2
(en)
|
2017-03-01 |
2019-07-02 |
Nymox Corporation |
Compositions and methods for improving sexual function
|
|
US11021529B2
(en)
|
2017-03-03 |
2021-06-01 |
Massachusetts Institute Of Technology |
Antimicrobial constructs and uses thereof
|
|
US10421968B2
(en)
|
2017-03-15 |
2019-09-24 |
Versitech Limited |
Amphiphilic dendrimers complexed with siRNA for treatment of cancer
|
|
JP7132939B2
(ja)
|
2017-03-24 |
2022-09-07 |
イントラ-セルラー・セラピーズ・インコーポレイテッド |
新規組成物および方法
|
|
KR102587810B1
(ko)
|
2017-04-25 |
2023-10-11 |
프로테라 바이오로직스, 인크. |
인터-알파 억제제 단백질을 정량화하는 방법
|
|
JP7185884B2
(ja)
|
2017-05-02 |
2022-12-08 |
国立研究開発法人国立精神・神経医療研究センター |
Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法
|
|
US20200071372A1
(en)
|
2017-05-04 |
2020-03-05 |
Helsingin Yliopisto |
C-terminal CDNF and MANF fragments, pharmaceutical compositions comprising same and uses thereof
|
|
IL270239B2
(en)
|
2017-05-05 |
2025-01-01 |
Amgen Inc |
Pharmaceutical composition containing bispecific antibody constructs for improved storage and delivery
|
|
CA3062749A1
(en)
|
2017-05-12 |
2018-11-15 |
Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. |
Compounds for use in the treatment or prevention of melanoma
|
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
|
US20190062428A1
(en)
|
2017-06-19 |
2019-02-28 |
Surface Oncology, Inc. |
Combination of anti-cd47 antibodies and cell death-inducing agents, and uses thereof
|
|
ES3036897T3
(en)
|
2017-06-19 |
2025-09-25 |
Talengen Int Ltd |
Plasminogen for use in treating parkinson's and alzheimer's disease
|
|
PE20200013A1
(es)
|
2017-06-20 |
2020-01-06 |
Amgen Inc |
Metodo para tratar o mejorar trastornos metabolicos con proteinas de union para el receptor peptidico inhibidor gastrico (gipr) en combinacion con agonistas de glp-1
|
|
MA49459A
(fr)
|
2017-06-21 |
2020-04-29 |
Amgen Inc |
Méthode de traitement ou d'amélioration des troubles métaboliques à l'aide de protéines de liaison antagonistes pour protéines de fusion agonistes du récepteur du peptide inhibiteur gastrique (gipr)/récepteur glp-1
|
|
MY202336A
(en)
|
2017-07-11 |
2024-04-24 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
|
JP2020528054A
(ja)
|
2017-07-19 |
2020-09-17 |
オークランド ユニサービシズ リミテッド |
サイトカインモジュレーション
|
|
EP3658145A4
(en)
|
2017-07-26 |
2021-04-21 |
Intra-Cellular Therapies, Inc. |
ORGANIC COMPOUNDS
|
|
US11427587B2
(en)
|
2017-07-26 |
2022-08-30 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
|
CN111164104A
(zh)
|
2017-08-09 |
2020-05-15 |
麻省理工学院 |
白蛋白结合肽缀合物及其方法
|
|
WO2019036605A2
(en)
|
2017-08-17 |
2019-02-21 |
Massachusetts Institute Of Technology |
MULTIPLE SPECIFICITY BINDING AGENTS OF CXC CHEMOKINES AND USES THEREOF
|
|
BR112020003670A2
(pt)
|
2017-08-22 |
2020-09-01 |
Sanabio, Llc |
receptores de interferon solúveis e usos dos mesmos
|
|
CA3076337A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
US12269898B2
(en)
|
2017-10-04 |
2025-04-08 |
Amgen Inc. |
Transthyretin immunoglobulin fusions
|
|
KR102771895B1
(ko)
|
2017-10-20 |
2025-02-21 |
가꼬우호우징 효고 이카다이가쿠 |
항il-6 수용체 항체를 함유하는 수술 후의 유착을 억제하기 위한 의약 조성물
|
|
MA50536A
(fr)
|
2017-10-30 |
2020-09-09 |
Enterin Inc |
Nouvelles formes solides de squalamine et procédés pour les produire
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
AR113491A1
(es)
|
2017-12-11 |
2020-05-06 |
Amgen Inc |
Proceso de elaboración continuo para productos de anticuerpos biespecíficos
|
|
WO2019117685A2
(ko)
|
2017-12-14 |
2019-06-20 |
에이비엘바이오 주식회사 |
항-igf1r 항체 및 그 용도
|
|
WO2019114839A1
(zh)
|
2017-12-15 |
2019-06-20 |
泰伦基国际有限公司 |
一种预防或治疗骨关节炎的方法和药物
|
|
CA3086205A1
(en)
|
2017-12-19 |
2019-06-27 |
Massachusetts Institute Of Technology |
Antigen-adjuvant coupling reagents and methods of use
|
|
JP7314146B2
(ja)
|
2017-12-28 |
2023-07-25 |
中外製薬株式会社 |
細胞傷害誘導治療剤
|
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
|
US20210363238A1
(en)
|
2018-01-31 |
2021-11-25 |
Motokazu Kato |
Therapeutic agent for asthma containing il-6 inhibitor
|
|
BR112020016144A2
(pt)
|
2018-02-09 |
2020-12-15 |
Nestlé Skin Health Sa |
Nemolizumabe no tratamento de dermatite atópica com escoriação moderada a grave
|
|
AU2019235842B2
(en)
|
2018-03-14 |
2022-02-03 |
Surface Oncology, Inc. |
Antibodies that bind CD39 and uses thereof
|
|
EP3765021A4
(en)
|
2018-03-16 |
2022-03-09 |
Intra-Cellular Therapies, Inc. |
NOVEL PROCESSES
|
|
SG11202008707YA
(en)
|
2018-03-22 |
2020-10-29 |
Surface Oncology Inc |
Anti-il-27 antibodies and uses thereof
|
|
WO2019183546A1
(en)
|
2018-03-23 |
2019-09-26 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
|
BR112020019119A2
(pt)
|
2018-03-23 |
2021-01-12 |
Intra-Cellular Therapies, Inc. |
Compostos orgânicos
|
|
TW202003015A
(zh)
|
2018-03-29 |
2020-01-16 |
赫爾辛基大學 |
C端腦部多巴胺神經滋養因子(cdnf)及中腦星狀細胞-衍生之神經滋養因子(manf)片段、包含彼之醫藥組成物及其用途
|
|
JP7405764B2
(ja)
|
2018-03-30 |
2023-12-26 |
アムジエン・インコーポレーテツド |
C末端抗体改変体
|
|
MA52205A
(fr)
|
2018-04-09 |
2021-02-17 |
Amgen Inc |
Protéines de fusion du facteur de différenciation de croissance 15
|
|
WO2019200357A1
(en)
|
2018-04-12 |
2019-10-17 |
Surface Oncology, Inc. |
Biomarker for cd47 targeting therapeutics and uses therefor
|
|
CN119286871A
(zh)
|
2018-04-19 |
2025-01-10 |
查美特制药公司 |
合成rig-i样受体激动剂
|
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
EP3797120A1
(en)
|
2018-05-21 |
2021-03-31 |
Compass Therapeutics LLC |
Compositions and methods for enhancing the killing of target cells by nk cells
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
|
CA3102948A1
(en)
|
2018-06-08 |
2019-12-12 |
Intra-Cellular Therapies, Inc. |
Novel methods
|
|
KR102778034B1
(ko)
|
2018-06-11 |
2025-03-12 |
인트라-셀룰라 써래피스, 인코퍼레이티드. |
치환된 헤테로환 융합 감마-카르볼린 합성
|
|
AU2019284362A1
(en)
|
2018-06-11 |
2021-01-07 |
University Of Florida Research Foundation, Inc. |
Materials and methods for treating stress-related disorders and cancer
|
|
CN112912110A
(zh)
|
2018-06-12 |
2021-06-04 |
安吉克公司 |
抗体-寡核苷酸缀合物
|
|
WO2020011938A1
(en)
|
2018-07-11 |
2020-01-16 |
Medizinische Universität Wien |
Glucocorticoids for the topical treatment of autoimmune gastritis
|
|
WO2020018715A1
(en)
|
2018-07-17 |
2020-01-23 |
Massachusetts Institute Of Technology |
Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
|
|
US12460004B2
(en)
|
2018-08-09 |
2025-11-04 |
Compass Therapeutics Llc |
Antibodies that bind CD277 and uses thereof
|
|
WO2020033925A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
|
WO2020033923A1
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antigen binding agents that bind cd277 and uses thereof
|
|
US12377294B2
(en)
|
2018-08-28 |
2025-08-05 |
Ambrx, Inc. |
Anti-CD3 antibody folate bioconjugates and their uses
|
|
JP2022500362A
(ja)
|
2018-08-29 |
2022-01-04 |
イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. |
新規組成物および方法
|
|
WO2020047408A1
(en)
|
2018-08-31 |
2020-03-05 |
Intra-Cellular Therapies, Inc. |
Novel methods
|
|
CN112584837A
(zh)
|
2018-08-31 |
2021-03-30 |
细胞内治疗公司 |
新方法
|
|
EP4389145A3
(en)
|
2018-09-11 |
2024-08-21 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and their uses
|
|
WO2020053808A1
(en)
|
2018-09-12 |
2020-03-19 |
Georg Dewald |
Method of diagnosing vasoregulatory disorders
|
|
EP3856763A1
(en)
|
2018-09-28 |
2021-08-04 |
Massachusetts Institute of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
JP7644706B2
(ja)
|
2018-10-11 |
2025-03-12 |
アムジエン・インコーポレーテツド |
二重特異性抗体コンストラクトの下流プロセシング
|
|
EP3867265A1
(en)
|
2018-10-19 |
2021-08-25 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
|
AU2019399474A1
(en)
|
2018-12-13 |
2021-06-03 |
Surface Oncology, LLC |
Anti-IL-27 antibodies and uses thereof
|
|
CN113423568A
(zh)
|
2018-12-17 |
2021-09-21 |
细胞内治疗公司 |
有机化合物
|
|
JP7499257B2
(ja)
|
2019-01-04 |
2024-06-13 |
リゾルブ セラピューティクス, エルエルシー |
ヌクレアーゼ融合タンパク質によるシェーグレン病の処置
|
|
US11680105B2
(en)
|
2019-01-17 |
2023-06-20 |
Regents Of The University Of Minnesota |
Antibody fragments for detecting cancer and methods of use
|
|
EP3914289A1
(en)
|
2019-01-23 |
2021-12-01 |
Massachusetts Institute of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
|
US11236157B2
(en)
|
2019-01-28 |
2022-02-01 |
Galderma Holding SA |
Treatment of skin lesions and pruritus in prurigo nodularis patients
|
|
GB201901305D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Specific binding molecules
|
|
JP7695885B2
(ja)
|
2019-02-12 |
2025-06-19 |
アンブルックス,インコーポレイテッド |
抗体-tlrアゴニストコンジュゲートを含有する組成物、その方法、及び使用
|
|
EP3941511A2
(en)
|
2019-03-20 |
2022-01-26 |
Massachusetts Institute of Technology |
Uses of amphiphiles in immune cell therapy and compositions therefor
|
|
US12357620B2
(en)
|
2019-03-22 |
2025-07-15 |
New York Medical College |
Use of rifaximin on circulating aged neutrophils in sickle cell disease
|
|
EP3949989A4
(en)
|
2019-03-29 |
2022-12-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti il-6 receptor antibody-containing inhibitor for inhibiting deterioration of bbb function
|
|
KR20220019670A
(ko)
|
2019-04-17 |
2022-02-17 |
고쿠리츠다이가쿠호진 히로시마다이가쿠 |
Il-6 저해제 및 ccr2 저해제를 조합하여 투여하는 것을 특징으로 하는 비뇨기암의 치료제
|
|
JP7455457B2
(ja)
|
2019-05-10 |
2024-03-26 |
タレンゲン インターナショナル リミテッド |
筋萎縮性側索硬化症を治療するための方法と薬剤
|
|
CN113924119A
(zh)
|
2019-05-31 |
2022-01-11 |
国立大学法人大阪大学 |
新型的消化器官癌治疗剂及其筛选方法
|
|
CA3142676A1
(en)
|
2019-06-05 |
2020-12-10 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody cleavage site binding molecule
|
|
KR102486064B1
(ko)
|
2019-06-10 |
2023-01-06 |
추가이 세이야쿠 가부시키가이샤 |
사이토카인 저해제와 조합하여 사용하기 위한 항t세포 항원 결합 분자
|
|
EP3983520A1
(en)
|
2019-06-13 |
2022-04-20 |
Amgen, Inc |
Automated biomass-based perfusion control in the manufacturing of biologics
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質-金属水酸化物錯体およびその方法
|
|
MX2022000143A
(es)
|
2019-07-07 |
2022-02-17 |
Intra Cellular Therapies Inc |
Metodos novedosos.
|
|
MX2021015976A
(es)
|
2019-07-08 |
2022-02-10 |
Amgen Inc |
Fusiones de inmunoglobulina y transtiretina multiespecificas.
|
|
MX2022000111A
(es)
|
2019-07-10 |
2022-02-10 |
Chugai Pharmaceutical Co Ltd |
Moleculas de union a claudina-6 y usos de las mismas.
|
|
MX2022000988A
(es)
|
2019-07-26 |
2022-05-03 |
Amgen Inc |
Proteinas de union a antigeno anti-il13.
|
|
GB201910899D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Binding members
|
|
GB201910900D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
|
|
TW202120534A
(zh)
|
2019-08-13 |
2021-06-01 |
美商安進公司 |
用於擴增調節性t細胞之介白素-2突變蛋白
|
|
GB201912657D0
(en)
|
2019-09-03 |
2019-10-16 |
Scancell Ltd |
Binding members
|
|
GB201912882D0
(en)
|
2019-09-06 |
2019-10-23 |
Scancell Ltd |
Ssea-4 binding members
|
|
EP4031178A1
(en)
|
2019-09-16 |
2022-07-27 |
Surface Oncology, Inc. |
Anti-cd39 antibody compositions and methods
|
|
WO2021062244A1
(en)
|
2019-09-25 |
2021-04-01 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
WO2021070885A1
(ja)
|
2019-10-11 |
2021-04-15 |
中外製薬株式会社 |
後天性血友病aの予防および/または治療に用いられる医薬組成物、および当該医薬組成物を含む製品
|
|
US20220378817A1
(en)
|
2019-10-23 |
2022-12-01 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
CA3158893A1
(en)
|
2019-10-24 |
2021-04-29 |
Minotaur Therapeutics, Inc. |
Chimeric cytokine modified antibodies and methods of use thereof
|
|
US11459389B2
(en)
|
2019-10-24 |
2022-10-04 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human CD161
|
|
WO2021097344A1
(en)
|
2019-11-13 |
2021-05-20 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
|
CA3160364A1
(en)
|
2019-11-19 |
2021-05-27 |
Modag Gmbh |
Compounds, and their use for the diagnosis, treatment and prevention of diseases associated with the aggregation of alpha-synuclein
|
|
JP7261942B2
(ja)
|
2019-12-11 |
2023-04-20 |
イントラ-セルラー・セラピーズ・インコーポレイテッド |
有機化合物
|
|
CA3162705A1
(en)
|
2019-12-17 |
2021-06-24 |
Amgen Inc. |
Dual interleukin-2 /tnf receptor agonist for use in therapy
|
|
EP3838912A1
(en)
|
2019-12-20 |
2021-06-23 |
Herantis Pharma Oyj |
Retro-inverso peptides
|
|
EP3838345A1
(en)
|
2019-12-20 |
2021-06-23 |
Herantis Pharma Oyj |
Macrocyclic peptides
|
|
TWI845803B
(zh)
|
2020-01-06 |
2024-06-21 |
美商法西尼克斯股份有限公司 |
抗ccr8抗體及其用途
|
|
WO2021146215A1
(en)
|
2020-01-13 |
2021-07-22 |
Durect Corporation |
Sustained release drug delivery systems with reduced impurities and related methods
|
|
CA3165026A1
(en)
|
2020-01-17 |
2021-07-22 |
Jinan Li |
Method for treatment of nerve injury and related disease
|
|
TWI787732B
(zh)
|
2020-02-06 |
2022-12-21 |
大陸商深圳瑞健生命科學研究院有限公司 |
一種預防和治療多發性硬化症的方法和藥物
|
|
WO2021160092A1
(zh)
|
2020-02-11 |
2021-08-19 |
泰伦基国际有限公司 |
一种治疗病毒性肺炎的方法和药物
|
|
WO2021173889A1
(en)
|
2020-02-26 |
2021-09-02 |
Ambrx, Inc. |
Uses of anti-cd3 antibody folate bioconjugates
|
|
US20230139956A1
(en)
|
2020-02-26 |
2023-05-04 |
Talengen International Limited |
Method and drug for preventing and treating abnormal blood pressure condition
|
|
JP2023517595A
(ja)
|
2020-03-11 |
2023-04-26 |
アンブルックス,インコーポレイテッド |
インターロイキン-2ポリペプチド結合物およびその使用方法
|
|
AU2021240028A1
(en)
|
2020-03-19 |
2022-09-15 |
Amgen Inc. |
Antibodies against mucin 17 and uses thereof
|
|
TWI868333B
(zh)
|
2020-03-24 |
2025-01-01 |
大陸商深圳瑞健生命科學研究院有限公司 |
一種治療阿茲海默症的方法和藥物
|
|
US20230141921A1
(en)
|
2020-03-24 |
2023-05-11 |
Talengen International Limited |
Method and medicine for treating huntington's disease
|
|
CN115697386A
(zh)
|
2020-03-24 |
2023-02-03 |
泰伦基国际有限公司 |
一种治疗帕金森病的方法和药物
|
|
JP2023518564A
(ja)
|
2020-03-24 |
2023-05-02 |
タレンゲン インターナショナル リミテッド |
ミスフォールドタンパク質およびその凝集体の分解を促進する方法及び薬剤
|
|
JP2023106635A
(ja)
|
2020-04-17 |
2023-08-02 |
中外製薬株式会社 |
二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法
|
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US20230181699A1
(en)
|
2020-05-11 |
2023-06-15 |
Talengen International Limited |
Method and drug for treating spinal muscular atrophy
|
|
EP4161520A1
(en)
|
2020-06-05 |
2023-04-12 |
The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone |
Acvr1 (alk2) receptor inhibition to treat neurological diseases
|
|
GB202101299D0
(en)
|
2020-06-09 |
2021-03-17 |
Avacta Life Sciences Ltd |
Diagnostic polypetides and methods
|
|
MX2022015764A
(es)
|
2020-06-19 |
2023-01-19 |
Chugai Pharmaceutical Co Ltd |
Molecula de union al antigeno anti-celulas t para usarse en combinacion con un inhibidor de angiogenesis.
|
|
US20230355722A1
(en)
|
2020-06-29 |
2023-11-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren’s syndrome with nuclease fusion proteins
|
|
WO2022023292A2
(en)
|
2020-07-31 |
2022-02-03 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Corona virus spike protein-targeting antibodies and use thereof
|
|
TW202220677A
(zh)
|
2020-07-31 |
2022-06-01 |
日商中外製藥股份有限公司 |
含有表現嵌合受體之細胞的醫藥組成物
|
|
WO2022040596A1
(en)
|
2020-08-20 |
2022-02-24 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
|
AU2021331410A1
(en)
|
2020-08-26 |
2023-04-06 |
Scancell Limited |
Nucleic acids encoding a polypeptide comprising a modified fc region of a human IGG1 and at least one heterologous antigen
|
|
WO2022081436A1
(en)
|
2020-10-15 |
2022-04-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody specific for sars-cov-2 receptor binding domain and therapeutic methods
|
|
WO2022087274A1
(en)
|
2020-10-21 |
2022-04-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that neutralize type-i interferon (ifn) activity
|
|
CN116323671A
(zh)
|
2020-11-06 |
2023-06-23 |
安进公司 |
具有增加的选择性的多靶向性双特异性抗原结合分子
|
|
EP4249504A4
(en)
|
2020-11-17 |
2024-07-24 |
Talengen International Limited |
Method and drug for increasing ngf level
|
|
TW202222337A
(zh)
|
2020-11-17 |
2022-06-16 |
大陸商深圳瑞健生命科學研究院有限公司 |
一種提高bdnf水平的方法和藥物
|
|
KR20230145053A
(ko)
|
2021-01-12 |
2023-10-17 |
듀렉트 코퍼레이션 |
지속 방출 약물 전달 시스템 및 관련 방법
|
|
WO2022178255A2
(en)
|
2021-02-19 |
2022-08-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
|
US20240158518A1
(en)
|
2021-03-12 |
2024-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for treatment or prevention of myasthenia gravis
|
|
JP2024512775A
(ja)
|
2021-04-03 |
2024-03-19 |
アンブルックス,インコーポレイテッド |
抗her2抗体薬物コンジュゲート及びその使用
|
|
CN118251420A
(zh)
|
2021-04-28 |
2024-06-25 |
米诺陶治疗公司 |
人源化嵌合牛抗体和使用方法
|
|
CA3217180A1
(en)
|
2021-05-06 |
2022-11-10 |
Amgen Research (Munich) Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
|
US20220389089A1
(en)
|
2021-05-07 |
2022-12-08 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
KR20240035394A
(ko)
|
2021-05-14 |
2024-03-15 |
클라리스 바이오쎄라퓨틱스, 인코포레이티드 |
안질환 치료를 위한 성장 인자 조성물
|
|
WO2023031881A1
(en)
|
2021-09-03 |
2023-03-09 |
University Of Bern |
Compositions and methods for treating long qt syndrome
|
|
JPWO2023053282A1
(no)
|
2021-09-29 |
2023-04-06 |
|
|
|
EP4426433A1
(en)
|
2021-11-03 |
2024-09-11 |
Affimed GmbH |
Bispecific cd16a binders
|
|
MX2024005106A
(es)
|
2021-11-03 |
2024-07-02 |
Affimed Gmbh |
Ligandos biespecificos de cd16a.
|
|
KR102707065B1
(ko)
|
2022-03-08 |
2024-09-19 |
동국제약 주식회사 |
코아세르베이션법을 이용하여 현탁성이 개선된 미립구의 제조방법
|
|
CA3255899A1
(en)
|
2022-04-19 |
2023-10-26 |
Philera New Zealand Ltd |
TREATMENT OF BRAIN COPPER DISORDERS
|
|
IL316597A
(en)
|
2022-05-12 |
2024-12-01 |
Amgen Res Munich Gmbh |
Multi-chain, multi-purpose, bispecific antigen-binding compounds with enhanced sensitivity
|
|
EP4525874A1
(en)
|
2022-05-18 |
2025-03-26 |
Intra-Cellular Therapies, Inc. |
Novel methods
|
|
US12414948B2
(en)
|
2022-05-18 |
2025-09-16 |
Intra-Cellular Therapies, Inc. |
Methods
|
|
US20240026001A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
US20240025987A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
JPWO2023243689A1
(no)
|
2022-06-16 |
2023-12-21 |
|
|
|
KR20250081950A
(ko)
|
2022-09-02 |
2025-06-05 |
갈더마 홀딩 소시에떼 아노님 |
결절성 양진의 치료법
|
|
AR130384A1
(es)
|
2022-09-02 |
2024-12-04 |
Univ Of Bern |
Composiciones y métodos para tratar el síndrome de qt largo
|
|
TW202421650A
(zh)
|
2022-09-14 |
2024-06-01 |
美商安進公司 |
雙特異性分子穩定組成物
|
|
WO2024076995A1
(en)
|
2022-10-03 |
2024-04-11 |
Insigna Inc. |
Compositions for non-surgical prevention of boar taint and aggressive behavior
|
|
EP4606896A1
(en)
|
2022-10-18 |
2025-08-27 |
NB Health Laboratory Co. Ltd. |
Antibody, nucleic acid, cell, and pharmaceutical
|
|
CN120152733A
(zh)
|
2022-11-04 |
2025-06-13 |
泰伦基国际有限公司 |
一种促进泛素蛋白酶体系统和自噬溶酶体系统对病理性蛋白清除的方法和药物
|
|
EP4613286A4
(en)
|
2022-11-04 |
2025-11-05 |
Talengen Int Ltd |
METHOD FOR PROMOTING THE PATHOLOGICAL DEGRADATION OF TDP-43 PROTEIN AND MEDICINE
|
|
EP4630537A1
(en)
|
2022-12-07 |
2025-10-15 |
Fondazione Matilde Tettamanti e Menotti de Marchi Onlus |
Methods for generating genetically modified cytokine induced killer (cik) cells
|
|
CN115804830B
(zh)
*
|
2022-12-16 |
2024-08-20 |
浙江圣兆药物科技股份有限公司 |
一种缩短迟滞期的戈舍瑞林缓释植入剂
|
|
EP4642458A1
(en)
|
2022-12-30 |
2025-11-05 |
Intra-Cellular Therapies, Inc. |
Heterocycle fused gamma-carbolines acting on the serotonine 5-ht2a receptor
|
|
WO2024173901A1
(en)
|
2023-02-17 |
2024-08-22 |
Intra-Cellular Therapies, Inc. |
Lumateperone and derivatives thereof for modulating the nervous system
|
|
WO2025006676A2
(en)
|
2023-06-27 |
2025-01-02 |
Firecyte Therapeutics, Inc. |
Insulin-like growth factor binding protein like 1 (igfbpl1) compositions and methods of use thereof
|
|
WO2025111568A1
(en)
|
2023-11-22 |
2025-05-30 |
Intra-Cellular Therapies, Inc. |
Lumateperone and analogues, as 5-ht2a or 5-ht2a/d2 receptor modulators, for use in the treatment of psychiatric disorders caused by viral, bacterial, or autoimmune encephalitis, and of psychiatric symptoms thereof
|
|
WO2025147696A1
(en)
|
2024-01-05 |
2025-07-10 |
Resolve Therapeutics, Llc |
Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
|
|
WO2025155602A1
(en)
|
2024-01-16 |
2025-07-24 |
Genentech, Inc. |
Method of treating hemophilia a
|
|
WO2025191291A1
(en)
|
2024-03-14 |
2025-09-18 |
Universidad Complutense De Madrid |
Methods for the prevention or treatment of erectile dysfunction (ed) by administering slpis (secretory leukocyte protease inhibitors)
|
|
WO2025198912A1
(en)
|
2024-03-21 |
2025-09-25 |
Hoffmann-La Roche Inc. |
Methods of treating myasthenia gravis
|
|
WO2025226603A1
(en)
|
2024-04-22 |
2025-10-30 |
Surface Oncology, LLC |
Methods for treating cancer using anti-ccr8 antibodies
|