PL2320940T3 - Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3), oraz ich zastosowania - Google Patents

Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3), oraz ich zastosowania

Info

Publication number
PL2320940T3
PL2320940T3 PL09807162T PL09807162T PL2320940T3 PL 2320940 T3 PL2320940 T3 PL 2320940T3 PL 09807162 T PL09807162 T PL 09807162T PL 09807162 T PL09807162 T PL 09807162T PL 2320940 T3 PL2320940 T3 PL 2320940T3
Authority
PL
Poland
Prior art keywords
lag
human antibodies
lymphocyte activation
activation gene
bind lymphocyte
Prior art date
Application number
PL09807162T
Other languages
English (en)
Inventor
Kent B Thudium
Alan J Korman
Heidi Leblanc
Mark Yamanaka
Mark Selby
Kyra D Zens
Original Assignee
Squibb & Sons Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41669613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2320940(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Squibb & Sons Llc filed Critical Squibb & Sons Llc
Publication of PL2320940T3 publication Critical patent/PL2320940T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL09807162T 2008-08-11 2009-08-11 Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3), oraz ich zastosowania PL2320940T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18854808P 2008-08-11 2008-08-11
PCT/US2009/053405 WO2010019570A2 (en) 2008-08-11 2009-08-11 Human antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof
EP09807162.4A EP2320940B1 (en) 2008-08-11 2009-08-11 Human antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof

Publications (1)

Publication Number Publication Date
PL2320940T3 true PL2320940T3 (pl) 2015-08-31

Family

ID=41669613

Family Applications (3)

Application Number Title Priority Date Filing Date
PL19186310.9T PL3597216T3 (pl) 2008-08-11 2009-08-11 Przeciwciała ludzkie wiążące gen aktywacji limfocytów-3 (lag-3) oraz ich zastosowania
PL09807162T PL2320940T3 (pl) 2008-08-11 2009-08-11 Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3), oraz ich zastosowania
PL15156647T PL2905030T3 (pl) 2008-08-11 2009-08-11 Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3) oraz ich zastosowania

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL19186310.9T PL3597216T3 (pl) 2008-08-11 2009-08-11 Przeciwciała ludzkie wiążące gen aktywacji limfocytów-3 (lag-3) oraz ich zastosowania

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL15156647T PL2905030T3 (pl) 2008-08-11 2009-08-11 Przeciwciała ludzkie, które wiążą gen aktywacji limfocytów-3 (LAG-3) oraz ich zastosowania

Country Status (32)

Country Link
US (13) US20110150892A1 (pl)
EP (4) EP2320940B1 (pl)
JP (6) JP5647981B2 (pl)
KR (6) KR20170010901A (pl)
CN (4) CN102176921B (pl)
AR (3) AR072999A1 (pl)
AU (2) AU2009282134B2 (pl)
BR (1) BRPI0917470B8 (pl)
CA (1) CA2734335C (pl)
CL (4) CL2011000308A1 (pl)
CO (1) CO6351751A2 (pl)
CY (2) CY1116582T1 (pl)
DK (3) DK3597216T3 (pl)
EA (2) EA201590777A1 (pl)
ES (3) ES2768576T3 (pl)
HK (2) HK1151985A1 (pl)
HR (3) HRP20221191T1 (pl)
HU (2) HUE060029T2 (pl)
IL (4) IL210731A (pl)
LT (2) LT3597216T (pl)
MX (2) MX2011001250A (pl)
NZ (3) NZ602780A (pl)
PE (3) PE20190373A1 (pl)
PL (3) PL3597216T3 (pl)
PT (3) PT2905030T (pl)
SG (1) SG10201706497QA (pl)
SI (2) SI2905030T1 (pl)
SM (1) SMT201500125B (pl)
TN (1) TN2011000025A1 (pl)
TW (1) TWI491408B (pl)
WO (1) WO2010019570A2 (pl)
ZA (1) ZA201101009B (pl)

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