|
ES2434961T5
(es)
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
RU2321630C2
(ru)
|
2001-08-03 |
2008-04-10 |
Гликарт Биотекнолоджи АГ |
Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
JP5416338B2
(ja)
|
2003-05-09 |
2014-02-12 |
デューク ユニバーシティ |
Cd20特異的抗体およびその使用方法
|
|
RS55723B1
(sr)
*
|
2003-11-05 |
2017-07-31 |
Roche Glycart Ag |
Molekuli koji se vezuju za antigen sa povećanim afinitetom vezivanja za fc receptor i efektornom funkcijom
|
|
AU2005267028A1
(en)
*
|
2004-07-22 |
2006-02-02 |
Genentech, Inc. |
Method of treating Sjogren's syndrome
|
|
AU2005274905B2
(en)
|
2004-08-04 |
2010-12-23 |
Mentrik Biotech, Llc |
Variant Fc regions
|
|
AU2005294666A1
(en)
|
2004-10-05 |
2006-04-20 |
Genentech, Inc. |
Method for treating vasculitis
|
|
KR101569300B1
(ko)
|
2005-02-07 |
2015-11-13 |
로슈 글리카트 아게 |
Egfr 에 결합하는 항원 결합 분자, 이를 코딩하는 벡터, 및 그의 용도
|
|
BRPI0611445A2
(pt)
*
|
2005-05-09 |
2010-09-08 |
Glycart Biotechnology Ag |
molécula de ligação a antìgeno glicomanipulada, polinucleotìdeo, polipeptìdeo, vetor, célula hospedeira, método para produção, uso e composição farmacêutica
|
|
EP1902320B1
(en)
|
2005-05-20 |
2010-03-10 |
Genentech, Inc. |
Pretreatment of a biological sample from an autoimmune disease subject
|
|
CA2608818A1
(en)
*
|
2005-06-03 |
2006-12-14 |
Genentech, Inc. |
Method of producing antibodies with modified fucosylation level
|
|
SG164379A1
(en)
|
2005-07-21 |
2010-09-29 |
Genmab As |
Potency assays for antibody drug substance binding to an fc receptor
|
|
AU2012216702B2
(en)
*
|
2005-08-26 |
2014-12-04 |
Roche Glycart Ag |
Modified antigen binding molecules with altered cell signaling activity
|
|
CN103204935B
(zh)
*
|
2005-08-26 |
2014-12-10 |
罗氏格黎卡特股份公司 |
具有改变的细胞信号传导活性的修饰的抗原结合分子
|
|
WO2007055916A2
(en)
*
|
2005-11-07 |
2007-05-18 |
The Rockefeller University |
Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
|
|
US20080206246A1
(en)
*
|
2006-04-05 |
2008-08-28 |
Ravetch Jeffrey V |
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
|
|
US8470318B2
(en)
*
|
2005-11-07 |
2013-06-25 |
The Rockefeller University |
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
WO2007126439A2
(en)
|
2005-12-02 |
2007-11-08 |
Genentech, Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
|
|
TWI596111B
(zh)
|
2006-01-05 |
2017-08-21 |
建南德克公司 |
抗ephb4抗體及使用該抗體之方法
|
|
WO2007095506A1
(en)
*
|
2006-02-10 |
2007-08-23 |
Invitrogen Corporation |
Oligosaccharide modification and labeling of proteins
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
US10167332B2
(en)
*
|
2006-04-05 |
2019-01-01 |
The Rockefeller University |
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
|
|
NZ597251A
(en)
|
2006-05-30 |
2013-08-30 |
Genentech Inc |
Antibodies and immunoconjugates and uses therefor
|
|
WO2007143689A2
(en)
*
|
2006-06-06 |
2007-12-13 |
Genentech, Inc. |
Compositions and methods for modulating vascular development
|
|
AR062223A1
(es)
|
2006-08-09 |
2008-10-22 |
Glycart Biotechnology Ag |
Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas
|
|
CL2007002926A1
(es)
|
2006-10-12 |
2008-05-16 |
Genentech Inc |
Anticuerpo antilinfotoxina alfa (lt-alfa); composicion con el anticuerpo; hibridoma pta-7538; acido nucleico codificante del anticuerpo; vector y celula huesped que comprenden el acido nucleico; metodo para inhibir la proliferacion celular activada p
|
|
RU2483080C2
(ru)
|
2006-10-27 |
2013-05-27 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты и их применение
|
|
AU2013202392B2
(en)
*
|
2006-12-20 |
2016-02-25 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
|
EP2716657A3
(en)
|
2006-12-20 |
2014-10-08 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
|
EP2377527B1
(en)
|
2007-01-22 |
2013-07-17 |
Genentech, Inc. |
Polyelectrolyte precipitation and purification of antibodies
|
|
WO2008091222A1
(en)
*
|
2007-01-26 |
2008-07-31 |
Bioinvent International Ab |
Dll4 signaling inhibitors and uses thereof
|
|
EP2125896A2
(en)
|
2007-02-09 |
2009-12-02 |
Genetech, Inc. |
Anti-robo4 antibodies and uses therefor
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
FR2915398B1
(fr)
*
|
2007-04-25 |
2012-12-28 |
Lab Francais Du Fractionnement |
"ensemble de moyens pour le traitement d'une pathologie maligne, d'une maladie auto-immune ou d'une maladie infectieuse"
|
|
US20100291073A1
(en)
|
2007-05-14 |
2010-11-18 |
Medimmune, Llc |
Methods of reducing eosinophil levels
|
|
KR101573086B1
(ko)
|
2007-06-25 |
2015-11-30 |
에스바테크 - 어 노바티스 컴파니 엘엘씨 |
항체를 변형시키는 방법, 및 기능적 특성이 개선된 변형된 항체
|
|
JP5469600B2
(ja)
|
2007-07-16 |
2014-04-16 |
ジェネンテック, インコーポレイテッド |
抗CD79b抗体及びイムノコンジュゲートとその使用方法
|
|
SG183044A1
(en)
|
2007-07-16 |
2012-08-30 |
Genentech Inc |
Humanized anti-cd79b antibodies and immunoconjugatesand methods of use
|
|
RU2595383C2
(ru)
*
|
2007-09-05 |
2016-08-27 |
Ф.Хоффманн-Ля Рош Аг |
Комбинированная терапия антителами анти-cd20 типа i и типа ii
|
|
WO2009041613A1
(ja)
|
2007-09-26 |
2009-04-02 |
Chugai Seiyaku Kabushiki Kaisha |
抗体定常領域改変体
|
|
US20090098118A1
(en)
*
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
|
US20090110688A1
(en)
*
|
2007-10-24 |
2009-04-30 |
Georg Fertig |
Combination therapy of type ii anti-cd20 antibody with a proteasome inhibitor
|
|
NO2514436T3
(OSRAM)
|
2007-11-07 |
2018-05-19 |
|
|
|
AR069501A1
(es)
|
2007-11-30 |
2010-01-27 |
Genentech Inc |
Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
AU2008342956A1
(en)
*
|
2007-12-21 |
2009-07-09 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
|
ES2511844T3
(es)
*
|
2007-12-21 |
2014-10-23 |
F. Hoffmann-La Roche Ag |
Formulación de anticuerpo
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
UA106586C2
(uk)
|
2008-01-31 |
2014-09-25 |
Дженентек, Інк. |
Анти-cd79b антитіла, і імунокон'югати та способи їх застосування
|
|
TWI500624B
(zh)
*
|
2008-03-25 |
2015-09-21 |
Hoffmann La Roche |
具有增進之抗體依賴型細胞毒性之第ii型抗-cd20抗體之組合療法
|
|
NZ588853A
(en)
*
|
2008-03-31 |
2013-07-26 |
Genentech Inc |
Compositions and methods for treating and diagnosing asthma
|
|
MX2010011598A
(es)
*
|
2008-04-22 |
2010-12-15 |
Univ Rockefeller |
Metodos para identificar compuestos anti-inflamatorios.
|
|
US20090269339A1
(en)
*
|
2008-04-29 |
2009-10-29 |
Genentech, Inc. |
Responses to immunizations in rheumatoid arthritis patients treated with a cd20 antibody
|
|
KR101054362B1
(ko)
*
|
2008-07-03 |
2011-08-05 |
재단법인 목암생명공학연구소 |
재조합 단백질의 푸코스 함량을 감소시키는 방법
|
|
ES2442024T3
(es)
|
2008-07-15 |
2014-02-07 |
Academia Sinica |
Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
|
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
|
PL2352521T3
(pl)
|
2008-10-14 |
2021-03-08 |
Genentech, Inc. |
Warianty immunoglobuliny i ich zastosowania
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
EP3318573A1
(en)
|
2008-12-23 |
2018-05-09 |
F. Hoffmann-La Roche AG |
Mmunoglobulin variants with altered binding to protein a
|
|
NZ594665A
(en)
|
2009-03-20 |
2013-08-30 |
Genentech Inc |
Bispecific anti-her antibodies
|
|
AR075925A1
(es)
|
2009-03-25 |
2011-05-04 |
Genentech Inc |
Anticuerpos anti-alfa5beta1 (alfa5beta1: glicoproteina integrina) y sus usos
|
|
PE20120553A1
(es)
|
2009-03-25 |
2012-05-18 |
Genentech Inc |
Anticuerpos anti-fgfr3
|
|
AR075982A1
(es)
|
2009-03-31 |
2011-05-11 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo afucosilado y una o mas de las citoquinas seleccionadas de gm- csf humano, m -csf humano y/o il-3 humano y composicion
|
|
CN102369215B
(zh)
|
2009-04-02 |
2015-01-21 |
罗切格利卡特公司 |
包含全长抗体和单链Fab片段的多特异性抗体
|
|
ES2537100T3
(es)
|
2009-04-07 |
2015-06-02 |
Roche Glycart Ag |
Anticuerpos biespecíficos trivalentes
|
|
PE20120550A1
(es)
|
2009-04-07 |
2012-05-21 |
Roche Glycart Ag |
ANTICUERPOS BIESPECIFICOS ANTI-ErbB-3/ANTI-C-MET
|
|
CN102361883A
(zh)
|
2009-04-07 |
2012-02-22 |
罗氏格黎卡特股份公司 |
双特异性抗-ErbB-1/抗-c-Met抗体
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
US20100316639A1
(en)
|
2009-06-16 |
2010-12-16 |
Genentech, Inc. |
Biomarkers for igf-1r inhibitor therapy
|
|
EP2456547B2
(en)
|
2009-07-24 |
2024-03-06 |
F. Hoffmann-La Roche AG |
Stirrer system
|
|
AR077595A1
(es)
|
2009-07-27 |
2011-09-07 |
Genentech Inc |
Tratamientos de combinacion
|
|
NZ597531A
(en)
|
2009-07-31 |
2014-05-30 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
|
RU2012109451A
(ru)
|
2009-08-14 |
2013-09-27 |
Роше Гликарт Аг |
Комбинированная терапия на основе афукозилированного антитела к cd20 в сочетании с флударабином и/или митоксантроном
|
|
TWI409079B
(zh)
|
2009-08-14 |
2013-09-21 |
Roche Glycart Ag |
非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法
|
|
GB0914691D0
(en)
|
2009-08-21 |
2009-09-30 |
Lonza Biologics Plc |
Immunoglobulin variants
|
|
TWI412375B
(zh)
|
2009-08-28 |
2013-10-21 |
Roche Glycart Ag |
人類化抗cdcp1抗體
|
|
TW201113037A
(en)
|
2009-08-28 |
2011-04-16 |
Hoffmann La Roche |
Antibodies against CDCP1 for the treatment of cancer
|
|
ES2599076T3
(es)
|
2009-09-02 |
2017-01-31 |
Genentech, Inc. |
Smoothened mutante y métodos de utilización del mismo
|
|
AR078161A1
(es)
*
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
|
JP6091894B2
(ja)
|
2009-09-16 |
2017-03-15 |
ジェネンテック, インコーポレイテッド |
コイルドコイルおよび/またはテザー含有タンパク質複合体およびその使用
|
|
BR112012007760A2
(pt)
|
2009-10-07 |
2015-08-25 |
Macrogenics Inc |
Método de atenuar fucosilação pós translacional de uma região fc de igc humana, anticorpo que se liga especificamente a um antigeno de câncer caracteristico de um cancêr polipeptideo
|
|
JP5814925B2
(ja)
|
2009-10-22 |
2015-11-17 |
ジェネンテック, インコーポレイテッド |
抗ヘプシン抗体及びその使用方法
|
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
SMT201700248T1
(it)
|
2009-11-02 |
2017-07-18 |
Univ Washington |
Composizioni terapeutiche di nucleasi e metodi
|
|
US20120316071A1
(en)
|
2009-11-04 |
2012-12-13 |
Vaughn Smider |
Methods for affinity maturation-based antibody optimization
|
|
BR112012010153B1
(pt)
|
2009-11-05 |
2022-05-03 |
Genentech, Inc |
Método de produção de um anticorpo
|
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
JP5818805B2
(ja)
|
2009-12-11 |
2015-11-18 |
ジェネンテック, インコーポレイテッド |
抗vegf−c抗体及びその使用方法
|
|
NZ600262A
(en)
|
2009-12-22 |
2013-06-28 |
Roche Glycart Ag |
Anti-her3 antibodies and uses thereof
|
|
HUE027713T2
(en)
|
2009-12-23 |
2016-10-28 |
Hoffmann La Roche |
Anti-BV8 antibodies and their use
|
|
TW201129384A
(en)
*
|
2010-02-10 |
2011-09-01 |
Immunogen Inc |
CD20 antibodies and uses thereof
|
|
RU2577702C2
(ru)
|
2010-02-11 |
2016-03-20 |
Ф.Хоффманн-Ля Рош Аг |
3d-facs-анализ-adcc nk-клеток
|
|
WO2011103242A1
(en)
|
2010-02-18 |
2011-08-25 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
|
CA2791991A1
(en)
|
2010-03-24 |
2011-09-29 |
Genentech, Inc. |
Anti-lrp6 antibodies
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
EP2374816B1
(en)
|
2010-04-07 |
2016-09-28 |
Agency For Science, Technology And Research |
Binding molecules against Chikungunya virus and uses thereof
|
|
WO2011124635A1
(en)
|
2010-04-07 |
2011-10-13 |
Humalys |
Binding molecules against chikungunya virus and uses thereof
|
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
MX342590B
(es)
|
2010-04-27 |
2016-10-05 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo cd20 afucosilado con un inhibidor mtor.
|
|
WO2011143262A2
(en)
|
2010-05-10 |
2011-11-17 |
Sinica, Academia |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
|
RU2613886C2
(ru)
|
2010-06-03 |
2017-03-21 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты, визуализируемые при помощи иммуно-позитрон-эмиссионной томографии, и способы их применения
|
|
RU2577986C2
(ru)
|
2010-06-18 |
2016-03-20 |
Дженентек, Инк. |
Антитела против axl и способы их применения
|
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
|
EA201291482A1
(ru)
|
2010-07-09 |
2013-10-30 |
Байоджен Айдек Хемофилия Инк. |
Химерные факторы коагуляции
|
|
EP2409712A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile
|
|
EP2409993A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Anti-CD19 antibody having ADCC function with improved glycosylation profile
|
|
EP2409989A1
(en)
|
2010-07-19 |
2012-01-25 |
International-Drug-Development-Biotech |
Method to improve glycosylation profile for antibody
|
|
FR2962908A1
(fr)
|
2010-07-20 |
2012-01-27 |
Lfb Biotechnologies |
Formulation d'anticorps anti-cd20
|
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
|
JP2013541501A
(ja)
|
2010-08-03 |
2013-11-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
慢性リンパ性白血病(cll)のバイオマーカー
|
|
WO2012017003A1
(en)
|
2010-08-05 |
2012-02-09 |
F. Hoffmann-La Roche Ag |
Anti-mhc antibody anti-viral cytokine fusion protein
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP5841149B2
(ja)
|
2010-08-13 |
2016-01-13 |
ロシュ グリクアート アーゲー |
抗テネイシンca2抗体及び使用の方法
|
|
NO2603530T3
(OSRAM)
|
2010-08-13 |
2018-04-07 |
|
|
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
|
NZ604510A
(en)
|
2010-08-17 |
2013-10-25 |
Csl Ltd |
Dilutable biocidal compositions and methods of use
|
|
TW201208703A
(en)
*
|
2010-08-17 |
2012-03-01 |
Roche Glycart Ag |
Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody
|
|
WO2012025530A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
|
RU2013110874A
(ru)
|
2010-08-25 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против il-18r1 и их применения
|
|
JP2013537966A
(ja)
|
2010-08-31 |
2013-10-07 |
ジェネンテック, インコーポレイテッド |
バイオマーカー及び治療の方法
|
|
ES3005233T3
(en)
|
2010-10-01 |
2025-03-14 |
Modernatx Inc |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
JP5974012B2
(ja)
|
2010-10-05 |
2016-08-23 |
ジェネンテック, インコーポレイテッド |
突然変異体スムースンド及びその使用方法
|
|
WO2012064627A2
(en)
|
2010-11-08 |
2012-05-18 |
Genentech, Inc. |
Subcutaneously administered anti-il-6 receptor antibody
|
|
KR20130133205A
(ko)
|
2010-11-10 |
2013-12-06 |
제넨테크, 인크. |
신경계 질환 면역요법을 위한 방법 및 조성물
|
|
SI2646470T1
(sl)
|
2010-11-30 |
2017-05-31 |
F. Hoffmann-La Roche Ag |
Protitelesa proti receptorjem antitransferina in njihova uporaba za prenos terapevtskega enoverižnega variabilnega fragmenta (scfv) prek krvno-možganske pregrade
|
|
TR201815863T4
(tr)
|
2010-11-30 |
2018-11-21 |
Chugai Pharmaceutical Co Ltd |
Sitotoksisiteyi indükleyen terapötik madde.
|
|
WO2012080389A1
(en)
|
2010-12-16 |
2012-06-21 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mdm2 inhibitor
|
|
EP2652498B1
(en)
|
2010-12-16 |
2018-04-18 |
F.Hoffmann-La Roche Ag |
Diagnosis and treatments relating to th2 inhibition
|
|
KR20140014116A
(ko)
|
2010-12-20 |
2014-02-05 |
제넨테크, 인크. |
항-메소텔린 항체 및 면역접합체
|
|
US20120195910A1
(en)
|
2010-12-22 |
2012-08-02 |
Genentech, Inc. |
Anti-pcsk9 antibodies and methods of use
|
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
US20120258073A1
(en)
|
2011-02-10 |
2012-10-11 |
Christian Gerdes |
Immunotherapy
|
|
WO2012116927A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Monovalent antigen binding proteins
|
|
MX341921B
(es)
|
2011-02-28 |
2016-09-07 |
Hoffmann La Roche |
Proteinas de union a antigeno.
|
|
EP3590965A1
(en)
|
2011-03-29 |
2020-01-08 |
Roche Glycart AG |
Antibody fc variants
|
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
|
EP2694551A1
(en)
|
2011-04-07 |
2014-02-12 |
Genentech, Inc. |
Anti-fgfr4 antibodies and methods of use
|
|
SI2704737T1
(en)
|
2011-04-29 |
2018-06-29 |
University Of Washington |
Therapeutic nuclease compositions and methods
|
|
WO2012146630A1
(en)
|
2011-04-29 |
2012-11-01 |
F. Hoffmann-La Roche Ag |
N-terminal acylated polypeptides, methods for their production and uses thereof
|
|
MX2013013054A
(es)
|
2011-05-12 |
2014-02-20 |
Genentech Inc |
Metodo de monitoreo de lc-ms/ms de reaccion multiple para detectar anticuerpos terapeuticos en muestras de animales utilizando peptidos de firma de estructura.
|
|
PL2710035T3
(pl)
|
2011-05-16 |
2017-09-29 |
F.Hoffmann-La Roche Ag |
Agoniści fgfr1 i sposoby stosowania
|
|
BR112013032235A2
(pt)
|
2011-06-15 |
2016-11-22 |
Hoffmann La Roche |
anticorpos do receptor de epo anti-humano e métodos de uso
|
|
FR2976811A1
(fr)
|
2011-06-22 |
2012-12-28 |
Lfb Biotechnologies |
Utilisation d'un anticorps anti-cd20 a haute adcc pour le traitement de la maladie de waldenstrom
|
|
MX354663B
(es)
|
2011-06-22 |
2018-03-14 |
Hoffmann La Roche |
Eliminación de células diana por parte de células t citotóxicas específicas de virus utilizando complejos que comprenden mhc de clase i.
|
|
WO2013003680A1
(en)
|
2011-06-30 |
2013-01-03 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
|
CA2842375A1
(en)
|
2011-08-17 |
2013-02-21 |
Erica Jackson |
Neuregulin antibodies and uses thereof
|
|
WO2013025944A1
(en)
|
2011-08-17 |
2013-02-21 |
Genentech, Inc. |
Inhibition of angiogenesis in refractory tumors
|
|
JP2014534806A
(ja)
|
2011-08-23 |
2014-12-25 |
ロシュ グリクアート アーゲー |
抗mcsp抗体
|
|
MX356947B
(es)
|
2011-08-23 |
2018-06-20 |
Roche Glycart Ag |
Anticuerpos bioespecíficos específicos para antígenos que activan células t y un antígeno tumoral y métodos de uso.
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
MX2014003094A
(es)
|
2011-09-15 |
2014-04-25 |
Genentech Inc |
Metodos para promover diferenciacion.
|
|
KR20140064971A
(ko)
|
2011-09-19 |
2014-05-28 |
제넨테크, 인크. |
c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료
|
|
KR101684750B1
(ko)
|
2011-09-23 |
2016-12-08 |
로슈 글리카트 아게 |
이중특이적 항-egfr/항-igf-1r 항체
|
|
EP3778889A1
(en)
*
|
2011-09-30 |
2021-02-17 |
Chugai Seiyaku Kabushiki Kaisha |
Ion concentration-dependent binding molecule library
|
|
JP2014531210A
(ja)
|
2011-09-30 |
2014-11-27 |
テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド |
TL1aに対する抗体およびその使用
|
|
RU2648950C2
(ru)
|
2011-10-03 |
2018-04-02 |
Модерна Терапьютикс, Инк. |
Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение
|
|
BR112014008212A2
(pt)
|
2011-10-05 |
2017-06-13 |
Genentech Inc |
método para tratar uma condição hepática, método de indução por diferenciação hepática e método de redução de proliferação anormal do ducto biliar
|
|
ES2687951T3
(es)
|
2011-10-14 |
2018-10-30 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-HtrA1 y procedimientos de uso
|
|
BR112014008590A2
(pt)
|
2011-10-15 |
2017-10-24 |
Genentech Inc |
métodos de uso de antagonistas de scd1
|
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
|
US9265817B2
(en)
|
2011-10-28 |
2016-02-23 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
|
SG11201401815XA
(en)
|
2011-10-28 |
2014-05-29 |
Genentech Inc |
Therapeutic combinations and methods of treating melanoma
|
|
CA2854806A1
(en)
|
2011-11-07 |
2013-05-16 |
Medimmune, Llc |
Multispecific and multivalent binding proteins and uses thereof
|
|
WO2013078170A1
(en)
|
2011-11-21 |
2013-05-30 |
Genentech, Inc. |
Purification of anti-c-met antibodies
|
|
US20130302274A1
(en)
*
|
2011-11-25 |
2013-11-14 |
Roche Glycart Ag |
Combination therapy
|
|
EP2788024A1
(en)
|
2011-12-06 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Antibody formulation
|
|
AU2012352180A1
(en)
|
2011-12-16 |
2014-07-31 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
ES2816078T3
(es)
|
2011-12-20 |
2021-03-31 |
Medimmune Llc |
Polipéptidos modificados para armazones de anticuerpo biespecífico
|
|
KR102166824B1
(ko)
|
2011-12-22 |
2020-10-19 |
에프. 호프만-라 로슈 아게 |
발현 벡터 구성원 조합, 신규한 제조 세포 생성 방법 및 폴리펩티드의 재조합적 제조를 위한 그의 용도
|
|
WO2013092720A1
(en)
|
2011-12-22 |
2013-06-27 |
F. Hoffmann-La Roche Ag |
Full length antibody display system for eukaryotic cells and its use
|
|
EP3816284A1
(en)
|
2011-12-22 |
2021-05-05 |
F. Hoffmann-La Roche AG |
Expression vector for antibody production in eukaryotic cells
|
|
AR089434A1
(es)
|
2011-12-23 |
2014-08-20 |
Genentech Inc |
Procedimiento para preparar formulaciones con alta concentracion de proteinas
|
|
JP2015506944A
(ja)
|
2012-01-18 |
2015-03-05 |
ジェネンテック, インコーポレイテッド |
Fgf19修飾薬を使用する方法
|
|
MX2014008157A
(es)
|
2012-01-18 |
2014-10-06 |
Genentech Inc |
Anticuerpos anti-lrp5 y metodos de uso.
|
|
RU2644341C2
(ru)
|
2012-02-10 |
2018-02-08 |
Дженентек, Инк. |
Одноцепочечные антитела и другие гетеромультимеры
|
|
RU2014133069A
(ru)
|
2012-02-11 |
2016-04-10 |
Дженентек, Инк. |
Транслокации r-спондина и способы с их использованием
|
|
BR112014018005B1
(pt)
|
2012-02-15 |
2021-06-29 |
F. Hoffmann-La Roche Ag |
Uso de um complexo não covalente imobilizado
|
|
RU2014136886A
(ru)
|
2012-03-27 |
2016-05-20 |
Дженентек, Инк. |
Диагностика и виды лечения, связанные с ингибиторами her3
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
WO2013151663A1
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
JP6242865B2
(ja)
|
2012-05-01 |
2017-12-06 |
ジェネンテック, インコーポレイテッド |
抗pmel17抗体および免疫複合体
|
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
|
SG10201709555SA
(en)
|
2012-05-18 |
2017-12-28 |
Genentech Inc |
High-concentration monoclonal antibody formulations
|
|
CN108992668B
(zh)
|
2012-05-21 |
2023-12-05 |
霍夫曼-拉罗奇有限公司 |
用于提高血脑屏障转运的安全性的方法
|
|
RU2625771C2
(ru)
|
2012-05-23 |
2017-07-18 |
Дженентек, Инк. |
Способ отбора терапевтических средств
|
|
AR091462A1
(es)
|
2012-06-15 |
2015-02-04 |
Genentech Inc |
Anticuerpos anti-pcsk9, formulaciones, dosificacion y metodos de uso
|
|
TW201402611A
(zh)
|
2012-06-21 |
2014-01-16 |
Univ Indiana Res & Tech Corp |
具有改變之fc效應子功能之腸促胰島素受體配體多肽fc區融合多肽及結合物
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
CA2871880A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
|
|
RU2015100656A
(ru)
|
2012-06-27 |
2016-08-20 |
Ф. Хоффманн-Ля Рош Аг |
Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения
|
|
SI2869837T1
(sl)
|
2012-07-04 |
2016-12-30 |
F. Hoffmann-La Roche Ag |
Protitelesa proti teofilinu in postopki uporabe
|
|
CN107973856B
(zh)
|
2012-07-04 |
2021-11-23 |
弗·哈夫曼-拉罗切有限公司 |
共价连接的抗原-抗体缀合物
|
|
CN104411725B
(zh)
|
2012-07-04 |
2018-09-28 |
弗·哈夫曼-拉罗切有限公司 |
抗生物素抗体及使用方法
|
|
RU2670491C2
(ru)
|
2012-07-05 |
2018-10-23 |
Дженентек, Инк. |
Система экспрессии и секреции
|
|
US20140030279A1
(en)
|
2012-07-09 |
2014-01-30 |
Spirogen Sarl |
Anti-cd22 antibodies and immunoconjugates
|
|
WO2014011520A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
|
WO2014011519A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
|
US20140030282A1
(en)
|
2012-07-09 |
2014-01-30 |
Genentech, Inc. |
Anti-cd79b antibodies and immunoconjugates
|
|
US9695233B2
(en)
|
2012-07-13 |
2017-07-04 |
Roche Glycart Ag |
Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
AR092044A1
(es)
|
2012-08-07 |
2015-03-18 |
Roche Glycart Ag |
Inmunoterapia mejorada
|
|
US9914956B2
(en)
|
2012-08-18 |
2018-03-13 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
|
US9547009B2
(en)
|
2012-08-21 |
2017-01-17 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
|
RS58928B1
(sr)
|
2012-08-29 |
2019-08-30 |
Hoffmann La Roche |
Transporter za krvno-moždanu barijeru
|
|
JP6408993B2
(ja)
*
|
2012-09-07 |
2018-10-17 |
ジェネンテック, インコーポレイテッド |
タイプII抗CD20抗体と選択的Bcl−2インヒビターの併用療法
|
|
JP6273205B2
(ja)
|
2012-10-05 |
2018-01-31 |
協和発酵キリン株式会社 |
ヘテロダイマータンパク質組成物
|
|
US10087250B2
(en)
|
2012-10-08 |
2018-10-02 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
|
WO2014067642A1
(en)
|
2012-11-05 |
2014-05-08 |
Mab Discovery Gmbh |
Method for the production of multispecific antibodies
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
US11230589B2
(en)
|
2012-11-05 |
2022-01-25 |
Foundation Medicine, Inc. |
Fusion molecules and uses thereof
|
|
EP2727942A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Bispecific antibodies against human EGFR, HER2, and HER3
|
|
EP2727941A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Method for the production of multispecific antibodies
|
|
EP2727943A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Trispecific antibodies against human EGFR, HER2 and HER3
|
|
MA38165A1
(fr)
|
2012-11-08 |
2018-07-31 |
Hoffmann La Roche |
Protéines de liaison à l'antigène her3 se liant à l'épingle à cheveux beta de her3
|
|
JP6386465B2
(ja)
|
2012-11-13 |
2018-09-05 |
ジェネンテック, インコーポレイテッド |
抗ヘマグルチニン抗体及び使用方法
|
|
HRP20220607T1
(hr)
|
2012-11-26 |
2022-06-24 |
Modernatx, Inc. |
Terminalno modificirana rna
|
|
CA2894225A1
(fr)
|
2012-12-17 |
2014-06-26 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Utilisation d'anticorps monoclonaux pour le traitement de l'inflammation et d'infections bacteriennes
|
|
RU2015129640A
(ru)
|
2012-12-21 |
2017-01-26 |
Ф.Хоффманн-Ля Рош Аг |
Связанные дисульфидом мультивалентные многофункциональные белки, содержащие молекулы гкгс класса 1
|
|
US20140194368A1
(en)
*
|
2013-01-04 |
2014-07-10 |
Beech Tree Labs, Inc. |
Method of Treating Cancer by Administration of Low Levels of Heat Shock Protein 70 (HSP70)
|
|
AR094403A1
(es)
|
2013-01-11 |
2015-07-29 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos anti-her3
|
|
RU2519546C1
(ru)
*
|
2013-01-16 |
2014-06-10 |
Общество С Ограниченной Ответственностью "Биоинтегратор" (Ооо "Биоинтегратор") |
КОНЪЮГАТЫ И МАЛЫЕ МОЛЕКУЛЫ, ВЗАИМОДЕЙСТВУЮЩИЕ С РЕЦЕПТОРОМ CD16а
|
|
US10980804B2
(en)
|
2013-01-18 |
2021-04-20 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
|
WO2014117220A1
(en)
|
2013-02-01 |
2014-08-07 |
Transbio Ltd |
Anti-cd83 antibodies and use thereof
|
|
ES2942636T3
(es)
|
2013-02-07 |
2023-06-05 |
Csl Ltd |
Proteínas de unión a IL-11R y usos de las mismas
|
|
KR20160002713A
(ko)
|
2013-02-13 |
2016-01-08 |
라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 |
고도로 갈락토실화된 항-tnf-알파 항체 및 이의 용도
|
|
HK1211235A1
(en)
|
2013-02-22 |
2016-05-20 |
霍夫曼-拉罗奇有限公司 |
Methods of treating cancer and preventing drug resistance
|
|
KR20180023035A
(ko)
|
2013-02-26 |
2018-03-06 |
로슈 글리카트 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
|
EP2961772A1
(en)
|
2013-02-26 |
2016-01-06 |
Roche Glycart AG |
Anti-mcsp antibodies
|
|
WO2014131694A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
MX2015011428A
(es)
|
2013-03-06 |
2016-02-03 |
Genentech Inc |
Metodos para tratar y prevenir la resistencia a los farmacos para el cancer.
|
|
WO2014164913A1
(en)
|
2013-03-12 |
2014-10-09 |
University Of Utah Research Foundation |
Compositions and methods for inducing apoptosis
|
|
SG11201507475UA
(en)
*
|
2013-03-13 |
2015-10-29 |
Genentech Inc |
Antibody formulations
|
|
WO2014152358A2
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
CA2905070A1
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
EP2970474B1
(en)
|
2013-03-14 |
2017-12-20 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
MY176706A
(en)
|
2013-03-15 |
2020-08-19 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
KR102233349B1
(ko)
|
2013-03-15 |
2021-03-31 |
에이씨 이뮨 에스.에이. |
항-타우(tau) 항체 및 사용 방법
|
|
HUE039291T2
(hu)
|
2013-03-15 |
2018-12-28 |
Hoffmann La Roche |
IL-22 polipeptidek és IL-22 FC fúziós fehérjék és alkalmazási eljárások
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
BR112015021521A2
(pt)
|
2013-03-15 |
2017-10-10 |
Genentech Inc |
anticorpos anti-crth2 e métodos para seu uso
|
|
US20160143910A1
(en)
|
2013-03-15 |
2016-05-26 |
Constellation Pharmaceuticals, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
|
CN105378075B
(zh)
|
2013-03-15 |
2022-04-05 |
Atyr 医药公司 |
组氨酰-trna合成酶-fc缀合物
|
|
HK1211963A1
(en)
|
2013-03-15 |
2016-06-03 |
豪夫迈.罗氏有限公司 |
Compositions and methods for diagnosis and treatment of hepatic cancers
|
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
|
PE20151925A1
(es)
|
2013-04-29 |
2015-12-26 |
Hoffmann La Roche |
Anticuerpos anti-igf-1r con abolicion de la union al fcrn y su utilizacion en el tratamiento de enfermedades oculares vasculares
|
|
CN105164157B
(zh)
|
2013-04-29 |
2024-05-28 |
豪夫迈·罗氏有限公司 |
Fc-受体结合的修饰的非对称抗体及使用方法
|
|
UA118029C2
(uk)
|
2013-04-29 |
2018-11-12 |
Ф. Хоффманн-Ля Рош Аг |
Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування
|
|
NZ711867A
(en)
*
|
2013-05-02 |
2020-07-31 |
Hoffmann La Roche |
Combination therapy of an afucosylated cd20 antibody with a cd22 antibody-drug conjugate
|
|
SI2992016T1
(en)
|
2013-05-02 |
2018-01-31 |
F. Hoffmann-La Roche Ag |
Combined treatment of an afcoxylated CD20 antibody with an antibody CD79b conjugate and a medicament
|
|
IL242088B2
(en)
|
2013-05-20 |
2023-12-01 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
|
WO2014210397A1
(en)
|
2013-06-26 |
2014-12-31 |
Academia Sinica |
Rm2 antigens and use thereof
|
|
US9981030B2
(en)
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
NZ715201A
(en)
|
2013-08-01 |
2021-12-24 |
Five Prime Therapeutics Inc |
Afucosylated anti-fgfr2iiib antibodies
|
|
US20150093399A1
(en)
|
2013-08-28 |
2015-04-02 |
Bioasis Technologies, Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
|
EP3041484B1
(en)
|
2013-09-06 |
2021-03-03 |
Academia Sinica |
Human inkt cell activation using glycolipids with altered glycosyl groups
|
|
KR20160055252A
(ko)
|
2013-09-17 |
2016-05-17 |
제넨테크, 인크. |
항-lgr5 항체의 사용 방법
|
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
|
DK3052192T3
(da)
|
2013-10-02 |
2020-09-28 |
Medimmune Llc |
Neutraliserende anti-influenza a-antistoffer og anvendelser deraf
|
|
KR20160067219A
(ko)
|
2013-10-03 |
2016-06-13 |
모더나 세라퓨틱스, 인코포레이티드 |
저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
|
|
EP4269421A3
(en)
|
2013-10-11 |
2023-12-27 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Tem8 antibodies and their use
|
|
CA2926084A1
(en)
|
2013-10-11 |
2015-04-16 |
Genentech, Inc. |
Nsp4 inhibitors and methods of use
|
|
KR20160044060A
(ko)
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
|
TWI658052B
(zh)
|
2013-10-18 |
2019-05-01 |
美商建南德克公司 |
抗-rspo抗體及使用方法
|
|
CA2924873A1
(en)
|
2013-10-23 |
2015-04-30 |
Genentech, Inc. |
Methods of diagnosing and treating eosinophilic disorders
|
|
PL3063275T3
(pl)
|
2013-10-31 |
2020-03-31 |
Resolve Therapeutics, Llc |
Terapeutyczne fuzje nukleaza-albumina i sposoby
|
|
CA2924268C
(en)
|
2013-11-21 |
2021-05-18 |
F. Hoffmann-La Roche Ag |
Anti-alpha-synuclein antibodies and methods of use
|
|
WO2015082446A1
(en)
|
2013-12-02 |
2015-06-11 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using an anti-cdcp1 antibody and a taxane
|
|
ES2758508T3
(es)
|
2013-12-09 |
2020-05-05 |
Allakos Inc |
Anticuerpos dirigidos contra Siglec-8 y métodos de uso de los mismos
|
|
MA39095A1
(fr)
|
2013-12-13 |
2018-08-31 |
Genentech Inc |
Anticorps et immunoconjugués anti-cd33
|
|
EP3527587A1
(en)
|
2013-12-17 |
2019-08-21 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-l1 binding antagonists
|
|
AU2014364593A1
(en)
|
2013-12-17 |
2016-07-07 |
Genentech, Inc. |
Methods of treating cancer using PD-1 axis binding antagonists and an anti-CD20 antibody
|
|
SG10201808519VA
(en)
|
2013-12-17 |
2018-10-30 |
Genentech Inc |
Methods of treating her2-positive cancers using pd-1 axis binding antagonists and anti-her2 antibodies
|
|
CN106029696B
(zh)
|
2013-12-17 |
2020-07-28 |
基因泰克公司 |
抗cd3抗体及使用方法
|
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
|
EP3089759B1
(en)
|
2014-01-03 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Covalently linked polypeptide toxin-antibody conjugates
|
|
RU2694981C2
(ru)
|
2014-01-03 |
2019-07-18 |
Ф. Хоффманн-Ля Рош Аг |
Ковалентно связанные конъюгаты хеликар-антитело против хеликара и их применения
|
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
RU2693438C2
(ru)
|
2014-01-03 |
2019-07-02 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифичные антитела против гаптена/против рецептора гематоэнцефалического барьера, их комплексы и их применение в качестве челноков гематоэнцефалического барьера
|
|
JP6557664B2
(ja)
|
2014-01-06 |
2019-08-07 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
一価の血液脳関門シャトルモジュール
|
|
RU2727639C2
(ru)
|
2014-01-15 |
2020-07-22 |
Ф.Хоффманн-Ля Рош Аг |
Варианты fc-области с модифицированной способностью связываться с fcrn и с сохраненной способностью связываться с белком а
|
|
JP2017507118A
(ja)
|
2014-01-16 |
2017-03-16 |
アカデミア シニカAcademia Sinica |
がんの処置および検出のための組成物および方法
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
EP3096797A1
(en)
|
2014-01-24 |
2016-11-30 |
F. Hoffmann-La Roche AG |
Methods of using anti-steap1 antibodies and immunoconjugates
|
|
DK3102197T3
(en)
|
2014-02-04 |
2018-11-19 |
Genentech Inc |
Smoothened mutant and methods for its use
|
|
NZ723884A
(en)
|
2014-02-08 |
2023-02-24 |
Genentech Inc |
Methods of treating alzheimer’s disease
|
|
SG11201606490YA
(en)
|
2014-02-08 |
2016-09-29 |
Genentech Inc |
Methods of treating alzheimer's disease
|
|
CA2936565C
(en)
|
2014-02-12 |
2020-08-11 |
Genentech, Inc. |
Anti-jagged1 antibodies and methods of use
|
|
EP3107574A2
(en)
|
2014-02-21 |
2016-12-28 |
F. Hoffmann-La Roche AG |
Anti-il-13/il-17 bispecific antibodies and uses thereof
|
|
AU2015222757B2
(en)
|
2014-02-28 |
2020-10-08 |
Allakos Inc. |
Methods and compositions for treating Siglec-8 associated diseases
|
|
KR102561695B1
(ko)
|
2014-03-14 |
2023-07-28 |
제넨테크, 인크. |
이형 폴리펩티드의 분비를 위한 방법 및 조성물
|
|
KR20160134687A
(ko)
|
2014-03-21 |
2016-11-23 |
에프. 호프만-라 로슈 아게 |
항체의 생체내 반감기의 시험관내 예측방법
|
|
WO2015140591A1
(en)
|
2014-03-21 |
2015-09-24 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
|
CA2943329A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
TWI687428B
(zh)
|
2014-03-27 |
2020-03-11 |
中央研究院 |
反應性標記化合物及其用途
|
|
MX2016012779A
(es)
|
2014-03-31 |
2017-04-27 |
Genentech Inc |
Terapia de combinacion con agentes antiangiogénesis y agonistas de unión a ox40.
|
|
WO2015153513A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Anti-ox40 antibodies and methods of use
|
|
KR20160143808A
(ko)
|
2014-04-11 |
2016-12-14 |
메디뮨 엘엘씨 |
이중특이적 her2 항체
|
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
|
WO2015179658A2
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
CA2944717A1
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
|
EP3149036A4
(en)
|
2014-05-27 |
2017-12-27 |
Academia Sinica |
Anti-cd20 glycoantibodies and uses thereof
|
|
KR102512592B1
(ko)
|
2014-05-27 |
2023-03-21 |
아카데미아 시니카 |
항-her2 글리코항체 및 이의 용도
|
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
CA2950423A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
AU2015267044A1
(en)
|
2014-05-28 |
2016-12-15 |
Academia Sinica |
Anti-TNF-alpha glycoantibodies and uses thereof
|
|
HRP20192038T1
(hr)
|
2014-05-30 |
2020-02-07 |
Henlix Biotech Co., Ltd. |
Protutijela receptora anti-epidermalnog faktora rasta (egfr)
|
|
WO2015191715A1
(en)
|
2014-06-11 |
2015-12-17 |
Genentech, Inc. |
Anti-lgr5 antibodies and uses thereof
|
|
CN107073121A
(zh)
|
2014-06-13 |
2017-08-18 |
基因泰克公司 |
治疗及预防癌症药物抗性的方法
|
|
BR112016029935A2
(pt)
|
2014-06-26 |
2017-10-31 |
Hoffmann La Roche |
?anticorpos anti-brdu, complexo, formulação farmacêutica e uso de anticorpo?
|
|
BR112017000130A2
(pt)
|
2014-07-11 |
2018-01-09 |
Genentech Inc |
método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer
|
|
ES2916923T3
(es)
|
2014-07-11 |
2022-07-06 |
Ventana Med Syst Inc |
Anticuerpos anti-PD-L1 y usos diagnósticos de los mismos
|
|
PE20211533A1
(es)
|
2014-08-04 |
2021-08-16 |
Hoffmann La Roche |
Moleculas biespecificas de unon a antigeno activadoras de celulas t
|
|
KR102615681B1
(ko)
|
2014-08-28 |
2023-12-18 |
바이오아트라, 인코퍼레이티드 |
변형된 t 세포에 대한 조건부 활성 키메라 항원 수용체
|
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
WO2016040369A2
(en)
|
2014-09-08 |
2016-03-17 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
|
|
WO2016037947A1
(en)
*
|
2014-09-10 |
2016-03-17 |
F. Hoffmann-La Roche Ag |
Galactoengineered immunoglobulin 1 antibodies
|
|
TW201625690A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
抗-cll-1抗體及免疫結合物
|
|
KR102508173B1
(ko)
|
2014-09-12 |
2023-03-10 |
제넨테크, 인크. |
항-her2 항체 및 면역콘주게이트
|
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
|
RU2704611C2
(ru)
|
2014-09-15 |
2019-10-30 |
Дженентек, Инк. |
Составы на основе антител
|
|
RU2727663C2
(ru)
|
2014-09-17 |
2020-07-22 |
Дженентек, Инк. |
Иммуноконъюгаты, содержащие антитела против her2 и пирролбензодиазепины
|
|
EP3689910A3
(en)
|
2014-09-23 |
2020-12-02 |
F. Hoffmann-La Roche AG |
Method of using anti-cd79b immunoconjugates
|
|
EP3207057A2
(en)
|
2014-10-16 |
2017-08-23 |
F. Hoffmann-La Roche AG |
Anti-alpha-synuclein antibodies and methods of use
|
|
AU2015336931B2
(en)
|
2014-10-23 |
2021-04-29 |
Kira Biotech Pty Limited |
CD83 binding proteins and uses thereof
|
|
EP3223865A4
(en)
|
2014-10-31 |
2018-10-03 |
Jounce Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind b7-h4
|
|
CN106796235B
(zh)
|
2014-11-03 |
2021-01-29 |
豪夫迈·罗氏有限公司 |
用于检测t细胞免疫子集的测定法及其使用方法
|
|
SG11201703521UA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
|
MX2017003478A
(es)
|
2014-11-05 |
2018-02-01 |
Genentech Inc |
Anticuerpos anti-fgfr2/3 y metodos para su uso.
|
|
HRP20191766T1
(hr)
|
2014-11-06 |
2019-12-27 |
F. Hoffmann - La Roche Ag |
Varijante fc regije s modificiranim vezanjem na neonatalni fc receptor (fcrn) i postupci primjene
|
|
EP3215536A1
(en)
|
2014-11-06 |
2017-09-13 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and tigit inhibitors
|
|
EP3842453A1
(en)
|
2014-11-06 |
2021-06-30 |
F. Hoffmann-La Roche AG |
Fc-region variants with modified fcrn- and protein a-binding properties
|
|
WO2016077369A1
(en)
|
2014-11-10 |
2016-05-19 |
Genentech, Inc. |
Animal model for nephropathy and agents for treating the same
|
|
EP3218403B1
(en)
|
2014-11-10 |
2020-05-13 |
F.Hoffmann-La Roche Ag |
Anti-interleukin-33 antibodies and uses thereof
|
|
DK3224275T3
(da)
|
2014-11-14 |
2020-05-04 |
Hoffmann La Roche |
Antigenbindende molekyler omfattende en TNF-familieligandtrimer
|
|
US10160795B2
(en)
|
2014-11-14 |
2018-12-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to Ebola virus glycoprotein and their use
|
|
KR20170096112A
(ko)
|
2014-11-17 |
2017-08-23 |
제넨테크, 인크. |
Ox40 결합 효능제 및 pd-1 축 결합 길항제를 포함하는 조합 요법
|
|
EP3221362B1
(en)
|
2014-11-19 |
2019-07-24 |
F.Hoffmann-La Roche Ag |
Anti-transferrin receptor antibodies and methods of use
|
|
CN107250158B
(zh)
|
2014-11-19 |
2022-03-25 |
基因泰克公司 |
抗转铁蛋白受体/抗bace1多特异性抗体和使用方法
|
|
EP3845565A3
(en)
|
2014-11-19 |
2021-09-08 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
|
HRP20201928T1
(hr)
|
2014-11-20 |
2021-02-05 |
F. Hoffmann - La Roche Ag |
Kombinirana terapija bispecifičnom antigen vezujućom molekulom koja aktivira t-stanice, za cd3 i folatni receptor 1 (folr1), i antagonistom vezivanja osi pd-1
|
|
MX2017006571A
(es)
|
2014-11-20 |
2017-09-29 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas activadoras de celulas t.
|
|
LT3221357T
(lt)
|
2014-11-20 |
2020-08-25 |
F. Hoffmann-La Roche Ag |
Bendros lengvosios grandinės ir naudojimo būdai
|
|
EP3227332B1
(en)
|
2014-12-03 |
2019-11-06 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
RS59203B1
(sr)
|
2014-12-05 |
2019-10-31 |
Hoffmann La Roche |
Anti-cd79b antitela i postupci primene
|
|
CN107207591A
(zh)
|
2014-12-10 |
2017-09-26 |
豪夫迈·罗氏有限公司 |
血脑屏障受体抗体及使用方法
|
|
IL278014B2
(en)
|
2014-12-19 |
2023-10-01 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variable FC regions and methods of use
|
|
JP6174782B2
(ja)
|
2014-12-19 |
2017-08-02 |
中外製薬株式会社 |
抗c5抗体および使用方法
|
|
WO2016111947A2
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
|
US20160208018A1
(en)
|
2015-01-16 |
2016-07-21 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for ror1
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
EP3247723A1
(en)
|
2015-01-22 |
2017-11-29 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
|
KR102691114B1
(ko)
|
2015-01-24 |
2024-08-01 |
아카데미아 시니카 |
신규한 글리칸 콘주게이트 및 이를 사용하는 방법
|
|
WO2016126972A1
(en)
|
2015-02-04 |
2016-08-11 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
CN107108729A
(zh)
|
2015-02-05 |
2017-08-29 |
中外制药株式会社 |
包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il‑8‑结合抗体,及其应用
|
|
KR20170140180A
(ko)
|
2015-02-24 |
2017-12-20 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
중동 호흡기 증후군 코로나 바이러스 면역원, 항체 및 그 용도
|
|
HK1247287A1
(zh)
|
2015-03-16 |
2018-09-21 |
F. Hoffmann-La Roche Ag |
检测和定量il-13的方法和在诊断和治疗th2相关疾病中的用途
|
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
|
ES2789348T3
(es)
|
2015-03-20 |
2020-10-26 |
Us Health |
Anticuerpos neutralizantes para GP120 y sus usos
|
|
JP6815329B2
(ja)
|
2015-03-23 |
2021-01-20 |
バイエル ファーマ アクチエンゲゼルシャフト |
抗ceacam6抗体およびその使用
|
|
TWI719970B
(zh)
|
2015-03-23 |
2021-03-01 |
美商永斯醫療股份有限公司 |
針對icos之抗體
|
|
MY186708A
(en)
|
2015-04-03 |
2021-08-11 |
Eureka Therapeutics Inc |
Constructs targeting afp peptide/mhc complexes and uses thereof
|
|
CN115932273A
(zh)
|
2015-04-24 |
2023-04-07 |
豪夫迈·罗氏有限公司 |
鉴定包含结合多肽的细菌的方法
|
|
CN107708986B
(zh)
*
|
2015-04-30 |
2019-12-13 |
富士胶片株式会社 |
装饰片
|
|
HK1250997A1
(zh)
|
2015-05-01 |
2019-01-18 |
基因泰克公司 |
掩蔽抗cd3抗体和使用方法
|
|
WO2016179194A1
(en)
|
2015-05-04 |
2016-11-10 |
Jounce Therapeutics, Inc. |
Lilra3 and method of using the same
|
|
CN107592812A
(zh)
*
|
2015-05-11 |
2018-01-16 |
豪夫迈·罗氏有限公司 |
治疗狼疮性肾炎的组合物和方法
|
|
AU2016262074A1
(en)
|
2015-05-12 |
2017-11-09 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
EP3708681A1
(en)
|
2015-05-29 |
2020-09-16 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for cancer
|
|
CN107771182A
(zh)
|
2015-05-29 |
2018-03-06 |
豪夫迈·罗氏有限公司 |
人源化抗埃博拉病毒糖蛋白抗体和使用方法
|
|
JP2018516933A
(ja)
|
2015-06-02 |
2018-06-28 |
ジェネンテック, インコーポレイテッド |
抗il−34抗体を使用して神経学的疾患を治療するための組成物及び方法
|
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
EP3302520B1
(en)
|
2015-06-04 |
2020-08-05 |
Ospedale San Raffaele S.r.l. |
Igfbp3 and uses thereof
|
|
AU2016272045B2
(en)
|
2015-06-04 |
2018-04-19 |
Ospedale San Raffaele Srl |
Inhibitor of IGFBP3/TMEM219 axis and diabetes
|
|
CA3258972A1
(en)
|
2015-06-05 |
2025-04-17 |
Ac Immune Sa |
TAU ANTIBODIES AND METHODS OF USING THEM
|
|
CN107810011A
(zh)
|
2015-06-08 |
2018-03-16 |
豪夫迈·罗氏有限公司 |
使用抗ox40抗体治疗癌症的方法
|
|
US20170000885A1
(en)
|
2015-06-08 |
2017-01-05 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
|
WO2016205176A1
(en)
|
2015-06-15 |
2016-12-22 |
Genentech, Inc. |
Antibodies and immunoconjugates
|
|
JP6996983B2
(ja)
|
2015-06-16 |
2022-02-21 |
ジェネンテック, インコーポレイテッド |
抗cll-1抗体及び使用方法
|
|
JP2018526972A
(ja)
|
2015-06-16 |
2018-09-20 |
ジェネンテック, インコーポレイテッド |
抗cd3抗体及び使用方法
|
|
PE20240218A1
(es)
|
2015-06-16 |
2024-02-16 |
Genentech Inc |
Anticuerpos madurados por afinidad y humanizados para fcrh5
|
|
LT3310812T
(lt)
|
2015-06-17 |
2025-10-10 |
|
Antikūnai prieš her2 ir jų naudojimo būdai
|
|
EP3310815A1
(en)
|
2015-06-17 |
2018-04-25 |
F. Hoffmann-La Roche AG |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
|
CA2987797A1
(en)
|
2015-06-17 |
2016-12-22 |
Christopher Robert Bebbington |
Methods and compositions for treating fibrotic diseases
|
|
EP3108897A1
(en)
|
2015-06-24 |
2016-12-28 |
F. Hoffmann-La Roche AG |
Antibodies against human csf-1r for use in inducing lymphocytosis in lymphomas or leukemias
|
|
CR20170537A
(es)
*
|
2015-06-24 |
2018-02-20 |
Hoffmann La Roche |
Anticuerpos contra csf-1r humano para uso en la inducción de linfocitosis en linfomas o leucemias.
|
|
MY193078A
(en)
|
2015-06-24 |
2022-09-26 |
Hoffmann La Roche |
Anti-transferrin receptor antibodies with tailored affinity
|
|
CN107531788B
(zh)
|
2015-06-24 |
2022-06-21 |
豪夫迈·罗氏有限公司 |
对her2和血脑屏障受体特异性的三特异性抗体及使用方法
|
|
US10906971B2
(en)
|
2015-06-26 |
2021-02-02 |
Sanofi Biotechnology SAS |
Monoclonal anti-IL-1RAcP antibodies
|
|
EP3514174B1
(en)
|
2015-06-29 |
2021-03-31 |
Ventana Medical Systems, Inc. |
Materials and methods for performing histochemical assays for human pro-epiregulin and amphiregulin
|
|
CN108473573A
(zh)
|
2015-06-29 |
2018-08-31 |
豪夫迈·罗氏有限公司 |
Ii型抗cd20抗体用于器官移植中
|
|
FR3038517B1
(fr)
|
2015-07-06 |
2020-02-28 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Utilisation de fragments fc modifies en immunotherapie
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
EP3341415B1
(en)
|
2015-08-28 |
2021-03-24 |
H. Hoffnabb-La Roche Ag |
Anti-hypusine antibodies and uses thereof
|
|
JP6904947B2
(ja)
|
2015-09-22 |
2021-07-21 |
スプリング バイオサイエンス コーポレーション |
抗ox40抗体及びその診断用途
|
|
RU2763916C2
(ru)
|
2015-09-23 |
2022-01-11 |
Дженентек, Инк. |
Оптимизированные варианты анти-vegf антител
|
|
RU2757135C2
(ru)
|
2015-09-24 |
2021-10-11 |
АБВИТРО ЭлЭлСи |
Композиции антител к вич и способы их применения
|
|
CR20220186A
(es)
|
2015-09-25 |
2022-07-07 |
Genentech Inc |
ANTICUERPOS ANTI-TIGIT Y MÉTODOS DE USO (divisional 2018-0225)
|
|
AU2016332900C1
(en)
|
2015-09-29 |
2024-07-04 |
Amgen Inc. |
ASGR inhibitors
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
BR112018000835A2
(pt)
|
2015-10-02 |
2018-09-11 |
Hoffmann La Roche |
molécula, um ou mais polinucleotídeos, um ou mais vetores, célula, método de produção da molécula, composição, uso da molécula, método de tratamento de uma doença e método para induzir a lise de uma célula-alvo
|
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
|
IL257110B
(en)
|
2015-10-02 |
2022-09-01 |
Hoffmann La Roche |
Bispecific antibodies specific against pd1 and tim3
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
CN108137697A
(zh)
|
2015-10-02 |
2018-06-08 |
豪夫迈·罗氏有限公司 |
双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
|
|
RU2761115C1
(ru)
|
2015-10-02 |
2021-12-06 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифические антитела, специфические в отношении костимуляторного tnf-рецептора
|
|
AU2016334623A1
(en)
|
2015-10-07 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies with tetravalency for a costimulatory TNF receptor
|
|
AU2016335750B2
(en)
|
2015-10-07 |
2023-05-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
|
US10604577B2
(en)
|
2015-10-22 |
2020-03-31 |
Allakos Inc. |
Methods and compositions for treating systemic mastocytosis
|
|
CA2998208A1
(en)
|
2015-10-22 |
2017-04-27 |
Jounce Therapeutics, Inc. |
Gene signatures for determining icos expression
|
|
WO2017072210A1
(en)
|
2015-10-29 |
2017-05-04 |
F. Hoffmann-La Roche Ag |
Anti-variant fc-region antibodies and methods of use
|
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
|
CN108289951A
(zh)
|
2015-10-30 |
2018-07-17 |
豪夫迈·罗氏有限公司 |
抗-因子d抗体和缀合物
|
|
EP3368578B1
(en)
|
2015-10-30 |
2021-03-17 |
H. Hoffnabb-La Roche Ag |
Anti-htra1 antibodies and methods of use thereof
|
|
AU2016349392B2
(en)
|
2015-11-03 |
2023-07-13 |
The Trustees Of Columbia University In The City Of New York |
Neutralizing antibodies to HIV-1 gp41 and their use
|
|
JP6998869B2
(ja)
|
2015-11-08 |
2022-02-04 |
ジェネンテック, インコーポレイテッド |
多重特異性抗体のスクリーニング方法
|
|
CA3004794A1
(en)
|
2015-11-23 |
2017-06-01 |
Five Prime Therapeutics, Inc. |
Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
ES2901794T3
(es)
|
2015-12-09 |
2022-03-23 |
Hoffmann La Roche |
Anticuerpo anti-CD20 de tipo II para reducir la formación de anticuerpos antifármaco
|
|
ES2969440T3
(es)
|
2015-12-18 |
2024-05-20 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos anti-C5 y métodos de uso
|
|
KR102709693B1
(ko)
|
2015-12-18 |
2024-09-24 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
CA3011739A1
(en)
|
2016-01-20 |
2017-07-27 |
Genentech, Inc. |
High dose treatments for alzheimer's disease
|
|
WO2017136558A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
|
JP6821693B2
(ja)
|
2016-02-29 |
2021-01-27 |
ジェネンテック, インコーポレイテッド |
がんのための治療方法及び診断方法
|
|
EP3423491A1
(en)
*
|
2016-03-01 |
2019-01-09 |
H. Hoffnabb-La Roche Ag |
Obinutuzumab variants having altered cell death induction
|
|
TW201808978A
(zh)
|
2016-03-08 |
2018-03-16 |
中央研究院 |
N-聚醣及其陣列之模組化合成方法
|
|
CN109153719B
(zh)
|
2016-03-15 |
2022-12-30 |
中外制药株式会社 |
使用pd-1轴结合拮抗剂和抗gpc3抗体治疗癌症的方法
|
|
RS64266B1
(sr)
|
2016-03-22 |
2023-07-31 |
Hoffmann La Roche |
Bispecifični molekul koji aktivira t ćeliju koji se aktivira proteazom
|
|
WO2017165734A1
(en)
|
2016-03-25 |
2017-09-28 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
|
CA3016035A1
(en)
*
|
2016-03-31 |
2017-10-05 |
Ngm Biopharmaceuticals, Inc. |
Binding proteins and methods of use thereof
|
|
US20170319688A1
(en)
|
2016-04-14 |
2017-11-09 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
|
WO2017181111A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
WO2017180842A1
(en)
|
2016-04-15 |
2017-10-19 |
Bioatla, Llc |
Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
|
KR20190003957A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암 모니터링 및 치료 방법
|
|
EP3889175A1
(en)
|
2016-05-02 |
2021-10-06 |
F. Hoffmann-La Roche AG |
The contorsbody - a single chain target binder
|
|
WO2017192589A1
(en)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to influenza ha and their use and identification
|
|
EP3241845A1
(en)
|
2016-05-06 |
2017-11-08 |
MAB Discovery GmbH |
Humanized anti-il-1r3 antibodies
|
|
CN109071640B
(zh)
|
2016-05-11 |
2022-10-18 |
豪夫迈·罗氏有限公司 |
经修饰抗生腱蛋白抗体及使用方法
|
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
|
CN109071652B
(zh)
|
2016-05-11 |
2022-09-23 |
豪夫迈·罗氏有限公司 |
包含tnf家族配体三聚体和生腱蛋白结合模块的抗原结合分子
|
|
LT3455261T
(lt)
|
2016-05-13 |
2022-11-10 |
Bioatla, Inc. |
Antikūnai prieš ror2, antikūnų fragmentai, jų imunokonjugatai ir panaudojimas
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
JP2019522633A
(ja)
|
2016-05-20 |
2019-08-15 |
ジェネンテック, インコーポレイテッド |
Protac抗体コンジュゲート及び使用方法
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
|
KR102680483B1
(ko)
|
2016-06-17 |
2024-07-01 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체 및 사용 방법
|
|
EP3257866A1
(en)
|
2016-06-17 |
2017-12-20 |
Academisch Medisch Centrum |
Modified anti-tnf antibody and use thereof in the treatment of ibd
|
|
CN116143918A
(zh)
|
2016-06-24 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
抗聚泛素多特异性抗体
|
|
MX2018015414A
(es)
*
|
2016-06-30 |
2019-08-01 |
Hoffmann La Roche |
Terapia de célula t adoptiva mejorada.
|
|
CN119120423A
(zh)
|
2016-07-01 |
2024-12-13 |
分解治疗有限责任公司 |
优化的二核酸酶融合体和方法
|
|
EP3478717B1
(en)
|
2016-07-04 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Novel antibody format
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
AU2017303205B2
(en)
|
2016-07-29 |
2024-08-01 |
Chugai Seiyaku Kabushiki Kaisha |
Bispecific antibody exhibiting increased alternative FVIII-cofactor-function activity
|
|
WO2018023100A2
(en)
|
2016-07-29 |
2018-02-01 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies and related methods
|
|
TWI831965B
(zh)
|
2016-08-05 |
2024-02-11 |
日商中外製藥股份有限公司 |
Il-8相關疾病之治療用或預防用組成物
|
|
CN109476748B
(zh)
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
|
US10538592B2
(en)
|
2016-08-22 |
2020-01-21 |
Cho Pharma, Inc. |
Antibodies, binding fragments, and methods of use
|
|
CN107384932B
(zh)
|
2016-08-31 |
2020-10-20 |
北京天广实生物技术股份有限公司 |
抗人cd20人源化单克隆抗体mil62、其制备方法及用途
|
|
CA3035081A1
(en)
|
2016-09-02 |
2018-03-08 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating b cell disorders
|
|
EP3510046A4
(en)
|
2016-09-07 |
2020-05-06 |
The Regents of the University of California |
ANTIBODIES AGAINST OXIDATION-SPECIFIC EPITOPES
|
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
|
CN116731197A
(zh)
|
2016-09-19 |
2023-09-12 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
|
NZ790629A
(en)
|
2016-09-23 |
2025-11-28 |
Genentech Inc |
Uses of il-13 antagonists for treating atopic dermatitis
|
|
JP7022123B2
(ja)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd3に対する二重特異性抗体
|
|
AU2017338827B2
(en)
|
2016-10-03 |
2023-08-31 |
Juno Therapeutics, Inc. |
HPV-specific binding molecules
|
|
WO2018065501A1
(en)
|
2016-10-05 |
2018-04-12 |
F. Hoffmann-La Roche Ag |
Methods for preparing antibody drug conjugates
|
|
CN110418851A
(zh)
|
2016-10-06 |
2019-11-05 |
基因泰克公司 |
癌症的治疗和诊断方法
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
JP2019535250A
(ja)
|
2016-10-29 |
2019-12-12 |
ジェネンテック, インコーポレイテッド |
抗mic抗体及び使用方法
|
|
SI3535298T1
(sl)
|
2016-11-02 |
2022-01-31 |
Jounce Therapeutics, Inc. |
Protitelesa proti pd-1 in njihove uporabe
|
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
CA3036983A1
(en)
|
2016-11-21 |
2018-05-24 |
Cureab Gmbh |
Anti-gp73 antibodies and immunoconjugates
|
|
WO2018106781A1
(en)
|
2016-12-07 |
2018-06-14 |
Genentech, Inc |
Anti-tau antibodies and methods of use
|
|
JP2020511937A
(ja)
|
2016-12-07 |
2020-04-23 |
ジェネンテック, インコーポレイテッド |
抗tau抗体及び使用方法
|
|
KR20190095921A
(ko)
|
2016-12-12 |
2019-08-16 |
제넨테크, 인크. |
항-pd-l1 항체 및 안티안드로겐을 사용하여 암을 치료하는 방법
|
|
EP3554542A1
(en)
|
2016-12-19 |
2019-10-23 |
H. Hoffnabb-La Roche Ag |
Combination therapy with targeted 4-1bb (cd137) agonists
|
|
WO2018114748A1
(en)
|
2016-12-20 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-cd20/anti-cd3 bispecific antibodies and 4-1bb (cd137) agonists
|
|
JOP20190134A1
(ar)
|
2016-12-23 |
2019-06-02 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
|
|
MX2019007795A
(es)
|
2017-01-03 |
2019-08-16 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas que comprenden el clon 20h4.9 anti-4-1bb.
|
|
WO2018129029A1
(en)
|
2017-01-04 |
2018-07-12 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
EP3568468A4
(en)
|
2017-01-12 |
2020-12-30 |
Eureka Therapeutics, Inc. |
RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES
|
|
AU2018217816A1
(en)
|
2017-02-10 |
2019-08-15 |
Genentech, Inc. |
Anti-tryptase antibodies, compositions thereof, and uses thereof
|
|
WO2018148660A1
(en)
|
2017-02-10 |
2018-08-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
|
AU2018228873A1
(en)
|
2017-03-01 |
2019-08-29 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
AU2018237359B2
(en)
|
2017-03-22 |
2024-06-27 |
Genentech, Inc. |
Optimized antibody compositions for treatment of ocular disorders
|
|
SG11201908326YA
(en)
|
2017-03-28 |
2019-10-30 |
Genentech Inc |
Methods of treating neurodegenerative diseases
|
|
WO2018178055A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
|
JP7205995B2
(ja)
|
2017-03-29 |
2023-01-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激性tnf受容体に対する二重特異性抗原結合分子
|
|
JOP20190203A1
(ar)
|
2017-03-30 |
2019-09-03 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها
|
|
MX2019011907A
(es)
|
2017-04-04 |
2020-01-09 |
Hoffmann La Roche |
Nuevas moleculas de union a antigeno biespecificas capaces de unirse especificamente a cd40 y a fap.
|
|
EP4516809A3
(en)
|
2017-04-05 |
2025-09-03 |
F. Hoffmann-La Roche AG |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
BR112019020940A2
(pt)
|
2017-04-11 |
2020-05-05 |
Inhibrx, Inc. |
construções polipeptídicas multipecíficas que têm ligação a cd3 restrita e métodos de usar as mesmas
|
|
TW201839400A
(zh)
|
2017-04-14 |
2018-11-01 |
美商建南德克公司 |
用於癌症之診斷及治療方法
|
|
US11767520B2
(en)
|
2017-04-20 |
2023-09-26 |
Atyr Pharma, Inc. |
Compositions and methods for treating lung inflammation
|
|
MX2019012419A
(es)
|
2017-04-21 |
2019-12-05 |
Genentech Inc |
Uso de antagonistas de klk5 para el tratamiento de una enfermedad.
|
|
SG11201909728XA
(en)
|
2017-04-26 |
2019-11-28 |
Eureka Therapeutics Inc |
Constructs specifically recognizing glypican 3 and uses thereof
|
|
SG11201909395TA
(en)
|
2017-04-27 |
2019-11-28 |
Tesaro Inc |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
|
CN110831628A
(zh)
|
2017-05-05 |
2020-02-21 |
爱乐科斯公司 |
用于治疗过敏性眼病的方法和组合物
|
|
EP3401332A1
(en)
|
2017-05-08 |
2018-11-14 |
MAB Discovery GmbH |
Anti-il-1r3 antibodies for use in inflammatory conditions
|
|
SG10202112636SA
(en)
|
2017-05-16 |
2021-12-30 |
Five Prime Therapeutics Inc |
Anti-fgfr2 antibodies in combination with chemotherapy agents in cancer treatment
|
|
WO2019011918A1
(en)
|
2017-07-10 |
2019-01-17 |
International - Drug - Development - Biotech |
TREATMENT OF LYMPHOCYTE B MALIGNANCIES USING AFUCOSYLATED PRO-APOPTOTIC ANTI-CD19 ANTIBODIES IN COMBINATION WITH ANTI-CD20 ANTIBODIES OR CHEMOTHERAPEUTIC AGENTS
|
|
MX2020000604A
(es)
|
2017-07-21 |
2020-09-10 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
|
AU2018308088B2
(en)
|
2017-07-25 |
2025-05-29 |
Truebinding, Inc. |
Treating cancer by blocking the interaction of TIM-3 and its ligand
|
|
AU2018308364C1
(en)
|
2017-07-26 |
2023-02-16 |
Forty Seven, LLC |
Anti-SIRP-alpha antibodies and related methods
|
|
JP2020528061A
(ja)
|
2017-07-26 |
2020-09-17 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
BET阻害剤、Bcl−2阻害剤及び抗CD20抗体を用いた併用療法
|
|
TWI772488B
(zh)
|
2017-08-08 |
2022-08-01 |
瑞士商赫孚孟拉羅股份公司 |
新穎DLBCL病患次族群之歐比托珠單抗(obinutuzumab)治療
|
|
CN107881160A
(zh)
|
2017-08-11 |
2018-04-06 |
百奥泰生物科技(广州)有限公司 |
一种由基因组被编辑的cho宿主细胞产生的具有独特糖谱的重组抗体及其制备方法
|
|
CN111511762B
(zh)
|
2017-08-21 |
2025-05-06 |
天演药业公司 |
抗cd137分子及其用途
|
|
EP3672986A1
(en)
|
2017-08-22 |
2020-07-01 |
Sanabio, LLC |
Soluble interferon receptors and uses thereof
|
|
EP3456738B1
(en)
*
|
2017-09-19 |
2024-07-17 |
Tillotts Pharma Ag |
Antibody variants
|
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
|
US11952408B2
(en)
|
2017-10-03 |
2024-04-09 |
Juno Therapeutics, Inc. |
HPV-specific binding molecules
|
|
CA3078974A1
(en)
|
2017-10-12 |
2019-04-18 |
Immunowake Inc. |
Vegfr-antibody light chain fusion protein
|
|
TWI805630B
(zh)
|
2017-10-19 |
2023-06-21 |
瑞士商赫孚孟拉羅股份公司 |
醫藥組合物
|
|
AU2018359506A1
(en)
|
2017-11-01 |
2020-04-23 |
F. Hoffmann-La Roche Ag |
Combination therapy with targeted OX40 agonists
|
|
MA49911A
(fr)
|
2017-11-01 |
2020-06-24 |
Juno Therapeutics Inc |
Anticorps et récepteurs antigéniques chimériques spécifiques de l'antigene de maturation des lymphocytes b
|
|
EP3703746A1
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tnf family ligand trimer-containing antigen binding molecules
|
|
IL272747B2
(en)
|
2017-11-01 |
2025-04-01 |
Hoffmann La Roche |
Bispecific antibodies 1 + 2
|
|
TW201923089A
(zh)
|
2017-11-06 |
2019-06-16 |
美商建南德克公司 |
癌症之診斷及治療方法
|
|
WO2019098212A1
(en)
|
2017-11-14 |
2019-05-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-c1s antibodies and methods of use
|
|
MX2020005662A
(es)
|
2017-12-01 |
2020-08-20 |
Pfizer |
Anticuerpos anti-cxcr5 y composiciones y usos de los mismos.
|
|
JP2021506817A
(ja)
|
2017-12-14 |
2021-02-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんを治療するための投与計画におけるcea cd3二重特異性抗体及びpd−1軸結合アンタゴニストの使用
|
|
MA51184A
(fr)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics Inc |
Molécules de liaison à l'anti-cct5 et procédés d'utilisation associés
|
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
|
AU2018389111A1
(en)
|
2017-12-22 |
2020-06-18 |
Jounce Therapeutics, Inc. |
Antibodies to LILRB2
|
|
WO2019126472A1
(en)
|
2017-12-22 |
2019-06-27 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
|
EP3732202A4
(en)
|
2017-12-28 |
2022-06-15 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST TIGIT
|
|
US12168688B2
(en)
|
2017-12-28 |
2024-12-17 |
Nanjing Legend Biotech Co., Ltd. |
Antibodies and variants thereof against PD-L1
|
|
EP3724223A1
(en)
|
2018-01-02 |
2020-10-21 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
|
AU2019205330B2
(en)
|
2018-01-04 |
2025-09-11 |
Iconic Therapeutics Llc |
Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
|
|
WO2019134981A1
(en)
|
2018-01-05 |
2019-07-11 |
Ac Immune Sa |
Misfolded tdp-43 binding molecules
|
|
EP3508499A1
(en)
|
2018-01-08 |
2019-07-10 |
iOmx Therapeutics AG |
Antibodies targeting, and other modulators of, an immunoglobulin gene associated with resistance against anti-tumour immune responses, and uses thereof
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
EP3740507A4
(en)
|
2018-01-15 |
2022-08-24 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST PD-1
|
|
US20200339686A1
(en)
|
2018-01-16 |
2020-10-29 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
|
BR112020015016A2
(pt)
|
2018-01-26 |
2020-12-29 |
Genentech, Inc. |
Composições farmacêuticas, métodos de tratamento da doença inflamatória intestinal, de inibição da infecção microbiana no intestino e de aceleração ou melhora da cicatrização de feridas
|
|
BR112020013420A2
(pt)
|
2018-01-26 |
2020-12-01 |
Genentech, Inc. |
composições, métodos para tratar doença, para inibir infecção, para tratar lesão, para acelerar ou aprimorar cura, para prevenir ou tratar uma afecção, para tratar síndrome, para tratar endotoxemia, para produzir uma composição, para selecionar um lote, para controlar o teor de ácido e uso
|
|
TWI800854B
(zh)
|
2018-02-01 |
2023-05-01 |
大陸商信達生物製藥(蘇州)有限公司 |
全人源的抗b細胞成熟抗原(bcma)單鏈抗體及其應用
|
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
|
CN118772288A
(zh)
|
2018-02-08 |
2024-10-15 |
豪夫迈·罗氏有限公司 |
双特异性抗原结合分子和使用方法
|
|
KR102417088B1
(ko)
|
2018-02-09 |
2022-07-07 |
제넨테크, 인크. |
비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
|
|
AU2019220395B2
(en)
|
2018-02-14 |
2025-12-04 |
Abba Therapeutics Ag |
Anti-human PD-L2 antibodies
|
|
AU2019226034A1
(en)
|
2018-02-21 |
2020-10-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to HIV-1 Env and their use
|
|
WO2019165140A1
(en)
|
2018-02-21 |
2019-08-29 |
Genentech, Inc. |
DOSING FOR TREATMENT WITH IL-22 Fc FUSION PROTEINS
|
|
WO2019165434A1
(en)
|
2018-02-26 |
2019-08-29 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
PL3765489T3
(pl)
|
2018-03-13 |
2025-02-10 |
F. Hoffmann-La Roche Ag |
Terapeutyczne połączenie agonistów 4-1BB z przeciwciałami anty-CD20
|
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
|
BR112020014591A2
(pt)
|
2018-03-14 |
2020-12-01 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
anticorpos anticlaudina 18.2
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
JP7508368B2
(ja)
|
2018-03-15 |
2024-07-01 |
中外製薬株式会社 |
ジカウイルスに対して交差反応性を有する抗デングウイルス抗体および使用方法
|
|
KR102874694B1
(ko)
|
2018-03-21 |
2025-10-23 |
파이브 프라임 테라퓨틱스, 인크. |
산성 pH에서 VISTA에 결합하는 항체
|
|
CN111886254B
(zh)
|
2018-03-30 |
2023-12-08 |
南京传奇生物科技有限公司 |
针对lag-3的单结构域抗体及其用途
|
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
|
RU2020135968A
(ru)
|
2018-04-05 |
2022-05-06 |
Джуно Терапьютикс, Инк. |
T-клеточные рецепторы и модифицированные клетки, экспрессирующие
|
|
IL323061A
(en)
|
2018-04-11 |
2025-10-01 |
Inhibrx Biosciences Inc |
Multispecific polypeptide constructs with forced CD3 binding and related methods and uses
|
|
PE20210652A1
(es)
|
2018-04-13 |
2021-03-26 |
Hoffmann La Roche |
Moleculas de union a antigeno dirigidas a her2 que comprenden 4-1bbl
|
|
EP3560945A1
(en)
|
2018-04-27 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Methods for purification of polypeptides using polysorbates
|
|
WO2019227490A1
(en)
|
2018-06-01 |
2019-12-05 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Compositions and methods for imaging
|
|
KR20210056288A
(ko)
|
2018-06-01 |
2021-05-18 |
타유 후아시아 바이오테크 메디컬 그룹 컴퍼니 리미티드 |
질환 또는 병태를 치료하기 위한 조성물 및 그의 용도
|
|
WO2019235426A1
(ja)
|
2018-06-04 |
2019-12-12 |
中外製薬株式会社 |
細胞質内での半減期が変化した抗原結合分子
|
|
TWI851577B
(zh)
|
2018-06-07 |
2024-08-11 |
美商思進公司 |
喜樹鹼結合物
|
|
WO2019245991A1
(en)
|
2018-06-18 |
2019-12-26 |
Eureka Therapeutics, Inc. |
Constructs targeting prostate-specific membrane antigen (psma) and uses thereof
|
|
JP7513530B2
(ja)
|
2018-06-22 |
2024-07-09 |
ジェンマブ ホールディング ビー.ブイ. |
抗cd37抗体および抗cd20抗体、組成物、ならびにそれらの使用方法
|
|
CN112585166A
(zh)
|
2018-06-23 |
2021-03-30 |
豪夫迈·罗氏有限公司 |
用pd-1轴结合拮抗剂、铂剂和拓扑异构酶ii抑制剂治疗肺癌的方法
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
WO2020007817A1
(en)
|
2018-07-04 |
2020-01-09 |
F. Hoffmann-La Roche Ag |
Novel bispecific agonistic 4-1bb antigen binding molecules
|
|
BR112021000169A2
(pt)
|
2018-07-09 |
2021-04-06 |
Millennium Pharmaceuticals, Inc. |
Ministração de inibidor de enzima ativadora de sumo e anticorpos anti-cd20
|
|
EP3820904A2
(en)
|
2018-07-09 |
2021-05-19 |
Five Prime Therapeutics, Inc. |
Antibodies binding to ilt4
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
CN121203021A
(zh)
|
2018-07-11 |
2025-12-26 |
戊瑞治疗有限公司 |
在酸性pH下结合至VISTA的抗体
|
|
US20200171146A1
(en)
|
2018-07-18 |
2020-06-04 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
|
JP7072715B2
(ja)
|
2018-07-20 |
2022-05-20 |
サーフィス オンコロジー インコーポレイテッド |
抗cd112r組成物及び方法
|
|
WO2020023553A1
(en)
|
2018-07-24 |
2020-01-30 |
Inhibrx, Inc. |
Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
|
|
SG11202101152QA
(en)
|
2018-08-03 |
2021-03-30 |
Chugai Pharmaceutical Co Ltd |
Antigen-binding molecule containing two antigen-binding domains that are linked to each other
|
|
CA3051549A1
(en)
|
2018-08-09 |
2020-02-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal fc receptor
|
|
CN112839960B
(zh)
|
2018-08-10 |
2024-09-06 |
中外制药株式会社 |
抗cd137抗原结合分子及其应用
|
|
CN112584863B
(zh)
|
2018-08-17 |
2025-10-28 |
Ab工作室有限公司 |
催化抗体和其使用方法
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
CN112673022B
(zh)
|
2018-09-10 |
2024-07-09 |
南京传奇生物科技有限公司 |
针对cd33的单结构域抗体及其构建体
|
|
JP2022501332A
(ja)
|
2018-09-19 |
2022-01-06 |
ジェネンテック, インコーポレイテッド |
膀胱がんの治療方法および診断方法
|
|
AU2019342133B8
(en)
|
2018-09-21 |
2025-08-07 |
Genentech, Inc. |
Diagnostic methods for triple-negative breast cancer
|
|
CN113286812B
(zh)
|
2018-09-27 |
2025-05-30 |
西里欧发展公司 |
掩蔽型细胞因子多肽
|
|
CN112955468B
(zh)
|
2018-10-01 |
2024-08-09 |
豪夫迈·罗氏有限公司 |
包含抗fap克隆212的双特异性抗原结合分子
|
|
JP2022511396A
(ja)
|
2018-10-01 |
2022-01-31 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd40への三価結合を伴う二重特異性抗原結合分子
|
|
EP3632929A1
(en)
|
2018-10-02 |
2020-04-08 |
Ospedale San Raffaele S.r.l. |
Antibodies and uses thereof
|
|
CN112804989A
(zh)
|
2018-10-05 |
2021-05-14 |
戊瑞治疗有限公司 |
抗fgfr2抗体制剂
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
JP7453219B2
(ja)
|
2018-10-11 |
2024-03-19 |
インヒブリックス, インコーポレイテッド |
Pd-1単一ドメイン抗体およびその治療用組成物
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
WO2020081767A1
(en)
|
2018-10-18 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
GB2596411B
(en)
*
|
2018-10-29 |
2023-09-20 |
Tigatx Inc |
Compositions and methods comprising IgA antibody constructs
|
|
CA3117856A1
(en)
|
2018-10-31 |
2020-05-07 |
Bayer Aktiengesellschaft |
Reversal agents for neutralizing the therapeutic activity of anti-fxia antibodies
|
|
BR112021009373A2
(pt)
|
2018-11-16 |
2021-08-17 |
Memorial Sloan Kettering Cancer Center |
anticorpos para mucina-16 e métodos de uso dos mesmos
|
|
BR112021009709A2
(pt)
|
2018-11-27 |
2021-10-19 |
Staidson (Beijing) Biopharmaceuticals Co., Ltd. |
ANTICORPOS ANTI-GM-CSFRa ISOLADOS, MOLÉCULA DE ÁCIDO NUCLEICO ISOLADA, VETOR, CÉLULAHOSPEDEIRA ISOLADA, SEUS USOS, COMPOSIÇÃO FARMACÊUTICA E MÉTODO DE PRODUÇÃO DE ANTICORPO ANTI-GM-CSFRa ISOLADO
|
|
MX2021006578A
(es)
|
2018-12-05 |
2021-07-07 |
Genentech Inc |
Procedimientos de diagnostico y composiciones para la inmunoterapia contra el cancer.
|
|
AU2018451747A1
(en)
|
2018-12-06 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Combination therapy of diffuse large B-cell lymphoma comprising an anti-CD79b immunoconjugates, an alkylating agent and an anti-CD20 antibody
|
|
EP3894427A1
(en)
|
2018-12-10 |
2021-10-20 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
|
JP2022514290A
(ja)
|
2018-12-20 |
2022-02-10 |
ジェネンテック, インコーポレイテッド |
改変抗体fcおよび使用方法
|
|
US20220089694A1
(en)
|
2018-12-20 |
2022-03-24 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Ebola virus glycoprotein-specific monoclonal antibodies and uses thereof
|
|
KR20210108981A
(ko)
|
2018-12-21 |
2021-09-03 |
에프. 호프만-라 로슈 아게 |
종양-표적화된 효현성 cd28 항원 결합 분자
|
|
CN113286822A
(zh)
|
2018-12-21 |
2021-08-20 |
豪夫迈·罗氏有限公司 |
靶向肿瘤的超激动性cd28抗原结合分子
|
|
EP3902833A2
(en)
|
2018-12-26 |
2021-11-03 |
City of Hope |
Activatable masked anti-ctla4 binding proteins
|
|
JP7650802B2
(ja)
|
2018-12-30 |
2025-03-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
抗ウサギcd19抗体および使用方法
|
|
AU2020208193A1
(en)
|
2019-01-14 |
2021-07-29 |
BioNTech SE |
Methods of treating cancer with a PD-1 axis binding antagonist and an RNA vaccine
|
|
EP3911675A1
(en)
|
2019-01-17 |
2021-11-24 |
Bayer Aktiengesellschaft |
Methods to determine whether a subject is suitable of being treated with an agonist of soluble guanylyl cyclase (sgc)
|
|
WO2020151572A1
(en)
|
2019-01-23 |
2020-07-30 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Anti-pd-l1 diabodies and the use thereof
|
|
JPWO2020153467A1
(ja)
|
2019-01-24 |
2021-12-02 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
MA54863A
(fr)
|
2019-01-29 |
2021-12-08 |
Juno Therapeutics Inc |
Anticorps et récepteurs antigéniques chimériques spécifiques du récepteur orphelin-1 de type récepteur à tyrosine kinase (ror1)
|
|
CA3127113A1
(en)
|
2019-01-30 |
2020-08-06 |
Dongxu Sun |
Anti-gal3 antibodies and uses thereof
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
SG11202108955QA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to nkp30 and uses thereof
|
|
AU2020228383A1
(en)
|
2019-02-27 |
2021-09-23 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-CD20 or anti-CD38 antibodies
|
|
TWI892981B
(zh)
|
2019-03-08 |
2025-08-11 |
美商建南德克公司 |
用於偵測且量化膜相關蛋白之方法
|
|
JP7730761B2
(ja)
|
2019-03-14 |
2025-08-28 |
ジェネンテック, インコーポレイテッド |
抗HER2 MABと組み合わせたHER2xCD3二重特異性抗体によるがんの処置
|
|
EP3952996A1
(en)
|
2019-04-12 |
2022-02-16 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules comprising lipocalin muteins
|
|
EP3956364A1
(en)
|
2019-04-19 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Anti-mertk antibodies and their methods of use
|
|
BR112021019571A2
(pt)
|
2019-04-19 |
2021-12-07 |
Chugai Pharmaceutical Co Ltd |
Receptor quimérico que reconhece o sítio de modificação do anticorpo
|
|
AU2020270376A1
(en)
|
2019-05-03 |
2021-10-07 |
Genentech, Inc. |
Methods of treating cancer with an anti-PD-L1 antibody
|
|
EP3962523A2
(en)
|
2019-05-03 |
2022-03-09 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
|
TW202108178A
(zh)
|
2019-05-14 |
2021-03-01 |
美商建南德克公司 |
使用抗CD79b免疫結合物治療濾泡性淋巴瘤之方法
|
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
|
US20220315648A1
(en)
|
2019-05-23 |
2022-10-06 |
Ac Immune Sa |
Anti-TDP-43 Binding Molecules and Uses Thereof
|
|
WO2020246563A1
(ja)
*
|
2019-06-05 |
2020-12-10 |
中外製薬株式会社 |
抗体切断部位結合分子
|
|
AU2020304813A1
(en)
|
2019-06-26 |
2022-01-06 |
F. Hoffmann-La Roche Ag |
Fusion of an antibody binding CEA and 4-1BBL
|
|
EP3990492A1
(en)
|
2019-06-27 |
2022-05-04 |
F. Hoffmann-La Roche AG |
Novel icos antibodies and tumor-targeted antigen binding molecules comprising them
|
|
MX2022000174A
(es)
|
2019-07-02 |
2022-05-20 |
Us Health |
Anticuerpos monoclonales que se enlazan a egfrviii y sus usos.
|
|
WO2021005009A1
(en)
|
2019-07-05 |
2021-01-14 |
Iomx Therapeutics Ag |
Antibodies binding igc2 of igsf11 (vsig3) and uses thereof
|
|
AU2020311511B2
(en)
|
2019-07-09 |
2024-08-29 |
Beijing Solobio Genetechnology Co., Ltd. |
Antibodies specifically recognizing Pseudomonas PcrV and uses thereof
|
|
US20220267452A1
(en)
|
2019-07-12 |
2022-08-25 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-mutation type fgfr3 antibody and use therefor
|
|
CA3148740A1
(en)
|
2019-08-06 |
2021-02-11 |
Aprinoia Therapeutics Limited |
Antibodies that bind to pathological tau species and uses thereof
|
|
MX2022002963A
(es)
|
2019-09-12 |
2022-04-06 |
Genentech Inc |
Composiciones y metodos para tratar nefritis lupica.
|
|
EP4031575A1
(en)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
|
WO2021055694A1
(en)
|
2019-09-20 |
2021-03-25 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
PE20221110A1
(es)
|
2019-09-27 |
2022-07-11 |
Genentech Inc |
Administracion de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1
|
|
WO2021076196A1
(en)
|
2019-10-18 |
2021-04-22 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
JP2022553803A
(ja)
|
2019-11-06 |
2022-12-26 |
ジェネンテック, インコーポレイテッド |
血液がんの処置のための診断方法及び治療方法
|
|
TWI895295B
(zh)
|
2019-11-12 |
2025-09-01 |
美商方得生醫療公司 |
偵測編碼新生抗原之融合基因之方法
|
|
WO2021094620A1
(en)
|
2019-11-15 |
2021-05-20 |
Enthera S.R.L. |
Tmem219 antibodies and therapeutic uses thereof
|
|
EP3822288A1
(en)
|
2019-11-18 |
2021-05-19 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Antibodies targeting, and other modulators of, the cd276 antigen, and uses thereof
|
|
WO2021099574A1
(en)
|
2019-11-21 |
2021-05-27 |
Enthera S.R.L. |
Igfbp3 antibodies and therapeutic uses thereof
|
|
JP2023504740A
(ja)
|
2019-12-06 |
2023-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
Bcma標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法
|
|
US20230192869A1
(en)
|
2019-12-06 |
2023-06-22 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
|
AR120741A1
(es)
|
2019-12-13 |
2022-03-16 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso
|
|
CN113045655A
(zh)
|
2019-12-27 |
2021-06-29 |
高诚生物医药(香港)有限公司 |
抗ox40抗体及其用途
|
|
PH12022551580A1
(en)
|
2019-12-27 |
2023-11-20 |
Chugai Pharmaceutical Co Ltd |
Anti-ctla-4 antibody and use thereof
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
JP7675083B2
(ja)
|
2020-01-09 |
2025-05-12 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
新規4-1bbl三量体含有抗原結合分子
|
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
KR20220148175A
(ko)
|
2020-01-29 |
2022-11-04 |
인히브릭스, 인크. |
Cd28 단일 도메인 항체 및 이의 다가 및 다중특이적 구조체
|
|
AU2021214795A1
(en)
|
2020-01-31 |
2022-08-18 |
The Cleveland Clinic Foundation |
Anti-Müllerian Hormone Receptor 2 antibodies and methods of use
|
|
CN115397459A
(zh)
|
2020-01-31 |
2022-11-25 |
基因泰克公司 |
用pd-1轴结合拮抗剂和rna疫苗诱导新表位特异性t细胞的方法
|
|
TWI895351B
(zh)
|
2020-02-12 |
2025-09-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
|
PH12022552122A1
(en)
|
2020-02-14 |
2024-01-29 |
Jounce Therapeutics Inc |
Antibodies and fusion proteins that bind to ccr8 and uses thereof
|
|
WO2021168292A1
(en)
|
2020-02-20 |
2021-08-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Epstein-barr virus monoclonal antibodies and uses thereof
|
|
EP3868396A1
(en)
|
2020-02-20 |
2021-08-25 |
Enthera S.R.L. |
Inhibitors and uses thereof
|
|
EP4112642A4
(en)
|
2020-02-28 |
2024-06-26 |
Shanghai Henlius Biotech, Inc. |
ANTI-CD137 CONSTRUCTION AND ITS USE
|
|
CN115151573A
(zh)
|
2020-02-28 |
2022-10-04 |
上海复宏汉霖生物技术股份有限公司 |
抗cd137构建体、多特异性抗体及其用途
|
|
TW202144410A
(zh)
|
2020-03-13 |
2021-12-01 |
美商建南德克公司 |
抗介白素-33抗體及其用途
|
|
MX2022011455A
(es)
|
2020-03-19 |
2022-10-03 |
Genentech Inc |
Anticuerpos anti-tgf-beta con selectividad de isoforma y metodos de uso.
|
|
JP2023518812A
(ja)
|
2020-03-23 |
2023-05-08 |
ジェネンテック, インコーポレイテッド |
Covid19肺炎を治療するための、トシリズマブとレムデシビルとの組み合わせ
|
|
EP4107184A1
(en)
|
2020-03-23 |
2022-12-28 |
Genentech, Inc. |
Method for treating pneumonia, including covid-19 pneumonia, with an il6 antagonist
|
|
JP2023518814A
(ja)
|
2020-03-23 |
2023-05-08 |
ジェネンテック, インコーポレイテッド |
Covid-19肺炎における、il-6アンタゴニストに対する応答を予測するためのバイオマーカー
|
|
EP4126949A1
(en)
|
2020-03-24 |
2023-02-08 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
|
EP4127724A1
(en)
|
2020-04-03 |
2023-02-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
WO2021207662A1
(en)
|
2020-04-10 |
2021-10-14 |
Genentech, Inc. |
Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome
|
|
JP7785016B2
(ja)
|
2020-04-24 |
2025-12-12 |
ジェネンテック, インコーポレイテッド |
抗CD79b免疫抱合体の使用方法
|
|
WO2021222181A2
(en)
|
2020-04-27 |
2021-11-04 |
The Regents Of The University Of California |
Isoform-independent antibodies to lipoprotein(a)
|
|
JP2023523450A
(ja)
|
2020-04-28 |
2023-06-05 |
ジェネンテック, インコーポレイテッド |
非小細胞肺がん免疫療法のための方法及び組成物
|
|
KR20230087414A
(ko)
|
2020-05-03 |
2023-06-16 |
레베나 (쑤저우) 바이오파마 컴퍼니 리미티드 |
항-Trop-2 항체를 포함하는 항체-약물 접합체 (ADCS), 상기 ADCS를 포함하는 조성물, 및 이의 제조 및 사용 방법
|
|
AU2021271971A1
(en)
|
2020-05-13 |
2023-02-02 |
Adagene Ag |
Compositions and methods for treating cancer
|
|
AU2021278935A1
(en)
|
2020-05-26 |
2022-12-08 |
Truebinding, Inc. |
Methods of treating inflammatory diseases by blocking Galectin-3
|
|
US20230220057A1
(en)
|
2020-05-27 |
2023-07-13 |
Staidson (Beijing) Biopharmaceuticals Co., Ltd. |
Antibodies specifically recognizing nerve growth factor and uses thereof
|
|
JP2023529842A
(ja)
|
2020-06-02 |
2023-07-12 |
ダイナミキュア バイオテクノロジー エルエルシー |
抗cd93構築物およびその使用
|
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
|
WO2021252977A1
(en)
|
2020-06-12 |
2021-12-16 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
|
MX2022015877A
(es)
|
2020-06-16 |
2023-01-24 |
Genentech Inc |
Metodos y composiciones para tratar cancer de mama triple negativo.
|
|
IL298946A
(en)
|
2020-06-18 |
2023-02-01 |
Genentech Inc |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
|
MX2022016069A
(es)
|
2020-06-19 |
2023-02-02 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19.
|
|
PE20231361A1
(es)
|
2020-06-23 |
2023-09-05 |
Hoffmann La Roche |
Moleculas agonistas de union al antigeno cd28 que se dirigen a her2
|
|
CN115916830A
(zh)
|
2020-06-25 |
2023-04-04 |
豪夫迈·罗氏有限公司 |
抗cd3/抗cd28双特异性抗原结合分子
|
|
US20240010720A1
(en)
|
2020-07-06 |
2024-01-11 |
Iomx Therapeutics Ag |
Antibodies binding igv of igsf11 (vsig3) and uses thereof
|
|
JP2023532764A
(ja)
|
2020-07-07 |
2023-07-31 |
エフ. ホフマン-ラ ロシュ アーゲー |
治療用タンパク質製剤の安定剤としての代替界面活性剤
|
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
|
CA3190328A1
(en)
|
2020-07-29 |
2022-02-03 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
|
WO2022031749A1
(en)
|
2020-08-03 |
2022-02-10 |
Genentech, Inc. |
Diagnostic and therapeutic methods for lymphoma
|
|
WO2022029660A1
(en)
|
2020-08-05 |
2022-02-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
|
JP2023536655A
(ja)
|
2020-08-07 |
2023-08-28 |
ジェネンテック, インコーポレイテッド |
Flt3リガンド融合タンパク質及び使用方法
|
|
TW202221026A
(zh)
|
2020-08-14 |
2022-06-01 |
瑞士商Ac 免疫有限公司 |
人源化抗tdp-43結合分子及其用途
|
|
WO2022043517A2
(en)
|
2020-08-27 |
2022-03-03 |
Cureab Gmbh |
Anti-golph2 antibodies for macrophage and dendritic cell differentiation
|
|
KR20230069171A
(ko)
|
2020-09-15 |
2023-05-18 |
바이엘 악티엔게젤샤프트 |
신규 항-a2ap 항체 및 그의 용도
|
|
EP4213877A1
(en)
|
2020-09-17 |
2023-07-26 |
Genentech, Inc. |
Results of empacta: a randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of tocilizumab in hospitalized patients with covid-19 pneumonia
|
|
CN118126190A
(zh)
|
2020-09-28 |
2024-06-04 |
安济盛生物医药有限公司 |
抗硬骨抑素构建体及其用途
|
|
JP2023544407A
(ja)
|
2020-10-05 |
2023-10-23 |
ジェネンテック, インコーポレイテッド |
抗FcRH5/抗CD3二重特異性抗体による処置のための投与
|
|
WO2022084210A1
(en)
|
2020-10-20 |
2022-04-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1 axis binding antagonists and lrrk2 inhitibors
|
|
AU2021366287A1
(en)
|
2020-10-20 |
2023-04-13 |
Kantonsspital St. Gallen |
Antibodies or antigen-binding fragments specifically binding to Gremlin-1 and uses thereof
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
CN116635425A
(zh)
|
2020-11-03 |
2023-08-22 |
德国癌症研究中心公共法律基金会 |
靶细胞限制性、共刺激性、双特异性二价抗cd28抗体
|
|
WO2022098638A2
(en)
|
2020-11-04 |
2022-05-12 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
TW202432189A
(zh)
|
2020-11-04 |
2024-08-16 |
美商建南德克公司 |
以抗 cd20/抗 cd3 雙特異性抗體和抗 cd79b 抗體藥物結合物治療的給藥方法
|
|
JP7716473B2
(ja)
|
2020-11-04 |
2025-07-31 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体の皮下投薬
|
|
JP2023549316A
(ja)
|
2020-11-16 |
2023-11-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Fapを標的としたcd40アゴニストとの併用療法
|
|
WO2022115865A2
(en)
|
2020-11-25 |
2022-06-02 |
Xilio Development, Inc. |
Tumor-specific cleavable linkers
|
|
TW202237639A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
鳥苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
|
JP2024503826A
(ja)
|
2021-01-06 |
2024-01-29 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd1-lag3二重特異性抗体及びcd20 t細胞二重特異性抗体を用いる併用療法
|
|
WO2022162587A1
(en)
|
2021-01-27 |
2022-08-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
AU2022212599A1
(en)
|
2021-01-28 |
2023-08-17 |
Universität Ulm |
Method and means for modulating b-cell mediated immune responses
|
|
CN117120084A
(zh)
|
2021-01-28 |
2023-11-24 |
维肯芬特有限责任公司 |
用于调节b细胞介导的免疫应答的方法和手段
|
|
WO2022162203A1
(en)
|
2021-01-28 |
2022-08-04 |
Vaccinvent Gmbh |
Method and means for modulating b-cell mediated immune responses
|
|
AU2022220611A1
(en)
|
2021-02-09 |
2023-08-24 |
University Of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
|
MX2023009244A
(es)
|
2021-02-09 |
2023-09-11 |
Us Health |
Anticuerpos contra la proteina espicular de coronavirus.
|
|
IL305181A
(en)
|
2021-02-15 |
2023-10-01 |
Takeda Pharmaceuticals Co |
Cell therapy compositions and methods for modulating tgf-b signaling
|
|
WO2022180145A2
(en)
|
2021-02-26 |
2022-09-01 |
Bayer Aktiengesellschaft |
Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding
|
|
CA3209364A1
(en)
|
2021-03-01 |
2022-09-09 |
Jennifer O'neil |
Combination of masked ctla4 and pd1/pdl1 antibodies for treating cancer
|
|
US20220306743A1
(en)
|
2021-03-01 |
2022-09-29 |
Xilio Development, Inc. |
Combination of ctla4 and pd1/pdl1 antibodies for treating cancer
|
|
EP4301418A1
(en)
|
2021-03-03 |
2024-01-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
WO2022187863A1
(en)
|
2021-03-05 |
2022-09-09 |
Dynamicure Biotechnology Llc |
Anti-vista constructs and uses thereof
|
|
MX2023010812A
(es)
|
2021-03-15 |
2023-09-27 |
Genentech Inc |
Composiciones y metodos para tratar la nefritis lupica.
|
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
|
TW202300648A
(zh)
|
2021-03-25 |
2023-01-01 |
美商當康生物科技有限公司 |
抗-igfbp7構築體及其用途
|
|
JP7659654B2
(ja)
|
2021-03-30 |
2025-04-09 |
バイエル・アクチエンゲゼルシヤフト |
抗sema3a抗体およびその用途
|
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
|
WO2022228706A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
|
AU2021443318A1
(en)
|
2021-04-30 |
2023-09-07 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
CA3218170A1
(en)
|
2021-05-12 |
2022-11-17 |
Jamie Harue HIRATA |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
BR112023023777A2
(pt)
|
2021-05-14 |
2024-01-30 |
Genentech Inc |
Anticorpos isolados, composição farmacêutica, ácido nucleico isolado, vetor isolado, célula hospedeira isolada, método para produzir um anticorpo, método para tratar uma condição associada à perda de função de trem2, método para reduzir os níveis de strem2 e uso de um anticorpo
|
|
CA3218578A1
(en)
|
2021-05-14 |
2022-11-17 |
Carol Elaine O'hear |
Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
|
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
|
WO2022255440A1
(en)
|
2021-06-04 |
2022-12-08 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ddr2 antibodies and uses thereof
|
|
WO2022258600A1
(en)
|
2021-06-09 |
2022-12-15 |
F. Hoffmann-La Roche Ag |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
|
BR112023025863A2
(pt)
|
2021-06-11 |
2024-03-05 |
Genentech Inc |
Métodos para tratar doença pulmonar obstrutiva crônica (dpoc), para reduzir a frequência de exacerbações moderadas a graves em um paciente com dpoc, para tratar ou prevenir dpoc, para manter e/ou melhorar a função pulmonar, para melhorar a contagem de linha de base de eosinófilos no sangue, kit, antagonistas de st2 e anticorpo anti-st2
|
|
WO2022263638A1
(en)
|
2021-06-17 |
2022-12-22 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
EP4355785A1
(en)
|
2021-06-17 |
2024-04-24 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
|
CN117545779B
(zh)
|
2021-06-25 |
2025-04-04 |
中外制药株式会社 |
抗ctla-4抗体的用途
|
|
TWI861519B
(zh)
|
2021-06-25 |
2024-11-11 |
日商中外製藥股份有限公司 |
抗ctla-4抗體
|
|
CN118103397A
(zh)
|
2021-07-08 |
2024-05-28 |
舒泰神(加州)生物科技有限公司 |
特异性识别tnfr2的抗体及其用途
|
|
KR20240058075A
(ko)
|
2021-07-14 |
2024-05-03 |
스테이드슨 (베이징) 바이오팔마슈티칼스 캄퍼니 리미티드 |
Cd40을 특이적으로 식별하는 항체 및 이의 응용
|
|
JP2024526880A
(ja)
|
2021-07-22 |
2024-07-19 |
ジェネンテック, インコーポレイテッド |
脳標的化組成物及びその使用方法
|
|
US20240336697A1
(en)
|
2021-08-07 |
2024-10-10 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
|
WO2023019239A1
(en)
|
2021-08-13 |
2023-02-16 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
|
CN117858905A
(zh)
|
2021-08-19 |
2024-04-09 |
豪夫迈·罗氏有限公司 |
多价抗变体fc区抗体及使用方法
|
|
CA3228359A1
(en)
|
2021-08-27 |
2023-03-02 |
Genentech, Inc. |
Methods of treating tau pathologies
|
|
JP2024534853A
(ja)
|
2021-08-30 |
2024-09-26 |
ジェネンテック, インコーポレイテッド |
抗ポリビキチン多重特異性抗体
|
|
US20240425606A1
(en)
|
2021-08-30 |
2024-12-26 |
Lassen Therapeutics 1, Inc. |
Anti-il-11ra antibodies
|
|
JP2024535249A
(ja)
|
2021-09-17 |
2024-09-30 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
合成ヒト化ラマナノボディライブラリーおよびsars-cov-2中和抗体を同定するためのその使用
|
|
WO2023049732A1
(en)
|
2021-09-21 |
2023-03-30 |
Qilu Puget Sound Biotherapeutics Corporation |
HETERODIMERIC Fc FOR MAKING FUSION PROTEINS AND BISPECIFIC ANTIBODIES
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
|
JPWO2023058723A1
(OSRAM)
|
2021-10-08 |
2023-04-13 |
|
|
|
WO2023081818A1
(en)
|
2021-11-05 |
2023-05-11 |
American Diagnostics & Therapy, Llc (Adxrx) |
Monoclonal antibodies against carcinoembryonic antigens, and their uses
|
|
WO2023086807A1
(en)
|
2021-11-10 |
2023-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
CA3235206A1
(en)
|
2021-11-16 |
2023-05-25 |
Davide BASCO |
Novel molecules for therapy and diagnosis
|
|
JP2024543509A
(ja)
|
2021-11-16 |
2024-11-21 |
ジェネンテック, インコーポレイテッド |
モスネツズマブで全身性エリテマトーデス(sle)を治療するための方法及び組成物
|
|
US20250066458A1
(en)
|
2021-12-06 |
2025-02-27 |
Beijing Solobio Genetechnology Co., Ltd. |
Bispecific Antibodies Specifically Binding to Klebsiella Pneumoniae O2 Antigen and O1 Antigen and Compositions Thereof
|
|
EP4448578A1
(en)
|
2021-12-17 |
2024-10-23 |
Shanghai Henlius Biotech, Inc. |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
|
KR20240122784A
(ko)
|
2021-12-17 |
2024-08-13 |
상하이 헨리우스 바이오테크, 인크. |
항-ox40 항체 및 사용 방법
|
|
CR20240246A
(es)
|
2021-12-20 |
2024-07-19 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecificos que los comprenden
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
WO2023154824A1
(en)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that broadly target coronaviruses
|
|
CA3243689A1
(en)
|
2022-02-16 |
2023-08-24 |
Ac Immune Sa |
Humanized Anti-TDP-43 Bonding Molecules and Their Uses
|
|
CA3252736A1
(en)
|
2022-02-18 |
2023-08-24 |
Rakuten Medical, Inc. |
Anti-PD-L1 (Programmed Death-Ligand 1) Antibody Molecules, Coding Polynucleotides, and Methods of Use
|
|
JP2025509286A
(ja)
|
2022-03-10 |
2025-04-11 |
ビバソル, インコーポレイテッド |
抗体-薬物コンジュゲートおよびその使用
|
|
KR20240164782A
(ko)
|
2022-03-23 |
2024-11-20 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이적 항체와 화학요법의 병용 치료
|
|
KR20240163119A
(ko)
|
2022-03-25 |
2024-11-18 |
상하이 헨리우스 바이오테크, 인크. |
항-msln 항체 및 사용 방법
|
|
CA3246703A1
(en)
|
2022-03-26 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
HIV-1 BISPECIFIC ENVELOPE ANTIBODIES AND THEIR USE
|
|
EP4499228A1
(en)
|
2022-03-28 |
2025-02-05 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
|
CA3246312A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
AU2023250038A1
(en)
|
2022-04-08 |
2024-11-14 |
Ac Immune Sa |
Anti-tdp-43 binding molecules
|
|
KR20250004768A
(ko)
|
2022-04-13 |
2025-01-08 |
제넨테크, 인크. |
치료 단백질의 약학적 조성물 및 사용 방법
|
|
CA3255366A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions based on bispecific anti-CD20/anti-CD3 antibodies and methods of use
|
|
WO2023203177A1
(en)
|
2022-04-20 |
2023-10-26 |
Kantonsspital St. Gallen |
Antibodies or antigen-binding fragments pan-specifically binding to gremlin-1 and gremlin-2 and uses thereof
|
|
TW202406934A
(zh)
|
2022-05-03 |
2024-02-16 |
美商建南德克公司 |
抗Ly6E抗體、免疫結合物及其用途
|
|
WO2023217068A1
(zh)
|
2022-05-09 |
2023-11-16 |
舒泰神(北京)生物制药股份有限公司 |
特异性识别gdf15的抗体及其应用
|
|
AU2022458320A1
(en)
|
2022-05-11 |
2024-11-28 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023235699A1
(en)
|
2022-05-31 |
2023-12-07 |
Jounce Therapeutics, Inc. |
Antibodies to lilrb4 and uses thereof
|
|
US11965032B1
(en)
|
2022-06-01 |
2024-04-23 |
Tg Therapeutics, Inc. |
Anti-CD20 antibody compositions
|
|
US11807689B1
(en)
*
|
2022-06-01 |
2023-11-07 |
Tg Therapeutics, Inc. |
Anti-CD20 antibody compositions
|
|
KR20250022049A
(ko)
|
2022-06-07 |
2025-02-14 |
제넨테크, 인크. |
항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법
|
|
WO2023237706A2
(en)
|
2022-06-08 |
2023-12-14 |
Institute For Research In Biomedicine (Irb) |
Cross-specific antibodies, uses and methods for discovery thereof
|
|
CA3261147A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
CN120322455A
(zh)
|
2022-07-19 |
2025-07-15 |
舒泰神(加州)生物科技有限公司 |
特异性识别b和t淋巴细胞衰减器(btla)的抗体及其应用
|
|
AR129995A1
(es)
|
2022-07-22 |
2024-10-23 |
Genentech Inc |
Moléculas de unión al antígeno anti-steap1 y sus usos
|
|
KR20250040994A
(ko)
|
2022-07-22 |
2025-03-25 |
브리스톨-마이어스 스큅 컴퍼니 |
인간 pad4에 결합하는 항체 및 그의 용도
|
|
EP4565329A1
(en)
|
2022-08-01 |
2025-06-11 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
|
EP4565330A1
(en)
|
2022-08-05 |
2025-06-11 |
Janssen Biotech, Inc. |
Transferrin receptor binding proteins for treating brain tumors
|
|
EP4565331A1
(en)
|
2022-08-05 |
2025-06-11 |
Janssen Biotech, Inc. |
Cd98 binding constructs for treating brain tumors
|
|
AU2023330110A1
(en)
|
2022-08-22 |
2025-03-06 |
Abdera Therapeutics Inc. |
Dll3 binding molecules and uses thereof
|
|
IL318749A
(en)
|
2022-08-26 |
2025-04-01 |
Juno Therapeutics Inc |
Delta-like ligand 3 (DLL3)-specific chimeric antigen receptors and antibodies
|
|
CN120153254A
(zh)
|
2022-09-01 |
2025-06-13 |
基因泰克公司 |
膀胱癌的治疗和诊断方法
|
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
|
WO2024054929A1
(en)
|
2022-09-07 |
2024-03-14 |
Dynamicure Biotechnology Llc |
Anti-vista constructs and uses thereof
|
|
KR20250060305A
(ko)
|
2022-09-21 |
2025-05-07 |
사노피 바이오테크놀로지 |
인간화 항-il-1r3 항체 및 사용 방법
|
|
WO2024064826A1
(en)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
|
CN119998321A
(zh)
|
2022-09-27 |
2025-05-13 |
舒泰神(北京)生物制药股份有限公司 |
特异性识别light的抗体及其应用
|
|
WO2024068996A1
(en)
|
2022-09-30 |
2024-04-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
|
AU2023365967A1
(en)
|
2022-10-20 |
2025-06-05 |
Beijing Solobio Genetechnology Co., Ltd. |
Antibody combination specifically binding to trail or fasl, and bispecific antibody
|
|
KR20250093336A
(ko)
|
2022-10-25 |
2025-06-24 |
제넨테크, 인크. |
다발성 골수종에 대한 치료 및 진단 방법
|
|
JP2025541593A
(ja)
|
2022-11-03 |
2025-12-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗cd19/抗cd28二重特異性抗体による併用療法
|
|
CN120051301A
(zh)
|
2022-11-04 |
2025-05-27 |
吉利德科学公司 |
使用抗ccr8抗体、化学疗法和免疫疗法组合的抗癌疗法
|
|
AU2023375342A1
(en)
|
2022-11-08 |
2025-04-24 |
F. Hoffmann-La Roche Ag |
Compositions and methods of treating childhood onset idiopathic nephrotic syndrome
|
|
JP2025538970A
(ja)
|
2022-11-09 |
2025-12-03 |
シーアイエス バイオファーマ アクツィエンゲゼルシャフト |
抗l1-cam抗体、並びに診断的及び治療的適用のためのそれらの使用
|
|
TW202435917A
(zh)
|
2022-11-17 |
2024-09-16 |
美商西雅圖遺傳學公司 |
Ceacam5抗體-藥物接合物及其使用方法
|
|
AR131163A1
(es)
|
2022-11-25 |
2025-02-19 |
Chugai Pharmaceutical Co Ltd |
Métodos para producir proteínas
|
|
EP4638491A1
(en)
|
2022-12-19 |
2025-10-29 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Monoclonal antibodies for treating sars-cov-2 infection
|
|
EP4491230A1
(en)
|
2023-07-14 |
2025-01-15 |
iOmx Therapeutics AG |
Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof
|
|
WO2024133940A2
(en)
|
2022-12-23 |
2024-06-27 |
Iomx Therapeutics Ag |
Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof
|
|
CN120530131A
(zh)
|
2023-01-06 |
2025-08-22 |
拉森医疗公司 |
抗il-18bp抗体
|
|
TW202434642A
(zh)
|
2023-01-06 |
2024-09-01 |
美商拉森醫療公司 |
用於治療甲狀腺眼病之抗IL—11Rα抗體
|
|
WO2024148241A1
(en)
|
2023-01-06 |
2024-07-11 |
Lassen Therapeutics 1, Inc. |
Anti-il-18bp antibodies
|
|
CN120917043A
(zh)
|
2023-03-08 |
2025-11-07 |
Ac免疫有限公司 |
抗tdp-43结合分子及其用途
|
|
EP4428158A1
(en)
|
2023-03-10 |
2024-09-11 |
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l. |
Lung cancer targeting human antibodies and therapeutic uses thereof
|
|
EP4428159A1
(en)
|
2023-03-10 |
2024-09-11 |
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l. |
Melanoma targeting human antibodies and therapeutic uses thereof
|
|
WO2024188965A1
(en)
|
2023-03-13 |
2024-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy employing a pd1-lag3 bispecific antibody and an hla-g t cell bispecific antibody
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
AU2024251934A1
(en)
|
2023-04-12 |
2025-10-30 |
Shanghai Kangabio Co., Limited |
Multifunctional molecules comprising masked interleukin 12 and methods of use
|
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|
|
AU2024270495A1
(en)
|
2023-05-05 |
2025-10-09 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2024233646A1
(en)
|
2023-05-10 |
2024-11-14 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
|
WO2024243355A1
(en)
|
2023-05-24 |
2024-11-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that target the rh5 complex of blood-stage plasmodium falciparum
|
|
WO2024246083A1
(en)
|
2023-06-01 |
2024-12-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies targeting bcma and cd28
|
|
WO2024246086A1
(en)
|
2023-06-01 |
2024-12-05 |
F. Hoffmann-La Roche Ag |
Immunostimulatory antigen binding molecules that specifically bind to bcma
|
|
WO2024254455A1
(en)
|
2023-06-08 |
2024-12-12 |
Genentech, Inc. |
Macrophage signatures for diagnostic and therapeutic methods for lymphoma
|
|
WO2024261013A1
(en)
|
2023-06-21 |
2024-12-26 |
F. Hoffmann-La Roche Ag |
Combination therapy with fap-targeted lymphotoxin beta receptor agonists
|
|
TW202504929A
(zh)
|
2023-06-22 |
2025-02-01 |
美商建南德克公司 |
用於癌症治療之方法及組成物
|
|
WO2025014896A1
(en)
|
2023-07-07 |
2025-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Humanized 40h3 antibody
|
|
WO2025024233A1
(en)
|
2023-07-21 |
2025-01-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bispecific antibodies that broadly target coronaviruses
|
|
WO2025024265A1
(en)
|
2023-07-21 |
2025-01-30 |
Bristol-Myers Squibb Company |
Methods of assessing citrullination and activity of pad4 modulators
|
|
WO2025021790A2
(en)
|
2023-07-24 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
WO2025034806A1
(en)
|
2023-08-08 |
2025-02-13 |
Wisconsin Alumni Research Foundation |
Single-domain antibodies and variants thereof against fibroblast activation protein
|
|
WO2025032069A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025032071A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025032070A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Anti-a-beta protein antibodies, methods and uses thereof
|
|
WO2025038492A1
(en)
|
2023-08-11 |
2025-02-20 |
Abalytics Oncology, Inc. |
Anti-ctla-4 antibodies and related binding molecules and methods and uses thereof
|
|
WO2025045250A1
(en)
|
2023-09-03 |
2025-03-06 |
Kira Pharmaceuticals (Us) Llc |
Anti-human factor d antibody constructs and uses thereof
|
|
WO2025064539A1
(en)
|
2023-09-19 |
2025-03-27 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Herv-e antibodies and methods of their use
|
|
EP4537907A1
(en)
|
2023-10-10 |
2025-04-16 |
Enthera S.r.l. |
Cd248 inhibitors and uses thereof
|
|
WO2025085489A1
(en)
|
2023-10-17 |
2025-04-24 |
Bristol-Myers Squibb Company |
Gspt1-degrading compounds, anti-cd33 antibodies and antibody-drug conjugates and uses thereof
|
|
TW202517674A
(zh)
|
2023-10-19 |
2025-05-01 |
德商拜耳廠股份有限公司 |
抗gpc3抗體及其放射性結合物
|
|
WO2025106427A1
(en)
|
2023-11-14 |
2025-05-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing and protective monoclonal antibodies against respiratory syncytial virus (rsv)
|
|
WO2025106474A1
(en)
|
2023-11-14 |
2025-05-22 |
Genentech, Inc. |
Therapeutic and diagnostic methods for treating cancer with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2025111402A1
(en)
|
2023-11-21 |
2025-05-30 |
Board Of Regents Of The University Of Nebraska |
Anti-amyloid beta antibodies and related compositions and methods thereof
|
|
WO2025117384A1
(en)
|
2023-12-01 |
2025-06-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Broadly neutralizing influenza hemagglutinin stem-directed antibodies
|
|
WO2025137344A1
(en)
|
2023-12-20 |
2025-06-26 |
Bristol-Myers Squibb Company |
Antibodies targeting il-18 receptor beta (il-18rβ) and related methods
|
|
WO2025137284A2
(en)
|
2023-12-21 |
2025-06-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Broadly neutralizing antibodies against sars-cov-2 and sars-cov variants
|
|
WO2025174974A1
(en)
|
2024-02-14 |
2025-08-21 |
Bristol-Myers Squibb Company |
Anti-cd33 antibodies and uses thereof
|
|
WO2025179281A1
(en)
|
2024-02-23 |
2025-08-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Treatment of cardiovascular disease with antxr1 antibodies
|
|
WO2025184416A1
(en)
|
2024-02-27 |
2025-09-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single-domain antibodies and bispecific antibodies against hiv-1 and their use
|
|
WO2025184421A1
(en)
|
2024-02-28 |
2025-09-04 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors and antibodies specific for delta-like ligand 3 (dll3) and related methods
|
|
WO2025199352A2
(en)
|
2024-03-20 |
2025-09-25 |
Juno Therapeutics, Inc. |
Antibodies specific for solute carrier family 34 member 2 (slc34a2)
|
|
WO2025196639A1
(en)
|
2024-03-21 |
2025-09-25 |
Seagen Inc. |
Cd25 antibodies, antibody-drug conjugates, and uses thereof
|
|
US20250333530A1
(en)
|
2024-04-12 |
2025-10-30 |
Hoffmann-La Roche Inc. |
Combination treatment of glofitamab and chemotherapy
|
|
WO2025218725A1
(zh)
*
|
2024-04-18 |
2025-10-23 |
徕特康(苏州)生物制药有限公司 |
靶向cd20和cd89的髓细胞衔接子抗体及其用途
|
|
WO2025226808A1
(en)
|
2024-04-24 |
2025-10-30 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
|
WO2025238187A1
(en)
|
2024-05-15 |
2025-11-20 |
Cis Biopharma Ag |
Immunoconjugates targeting l1-cam
|
|
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