US20020177688A1
(en)
*
|
1988-12-22 |
2002-11-28 |
Kirin-Amgen, Inc., |
Chemically-modified G-CSF
|
DE68925966T2
(de)
*
|
1988-12-22 |
1996-08-29 |
Kirin Amgen Inc |
Chemisch modifizierte granulocytenkolonie erregender faktor
|
US5581476A
(en)
*
|
1993-01-28 |
1996-12-03 |
Amgen Inc. |
Computer-based methods and articles of manufacture for preparing G-CSF analogs
|
US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
DE69534676T2
(de)
*
|
1994-02-08 |
2006-08-17 |
Amgen Inc., Thousand Oaks |
Orale Verabreichung von chemisch modifizierten Proteinen
|
US6001968A
(en)
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6429290B1
(en)
|
1994-08-17 |
2002-08-06 |
The Rockefeller University |
OB polypeptides, modified forms and derivatives
|
US20030053982A1
(en)
*
|
1994-09-26 |
2003-03-20 |
Kinstler Olaf B. |
N-terminally chemically modified protein compositions and methods
|
US5824784A
(en)
*
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
WO1996041813A2
(en)
*
|
1994-11-09 |
1996-12-27 |
Offord Robin E |
Functionalized polymers for site-specific attachment
|
US6008202A
(en)
*
|
1995-01-23 |
1999-12-28 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
JP2000507917A
(ja)
|
1995-11-02 |
2000-06-27 |
シェーリング コーポレイション |
持続的低用量サイトカイン注入治療
|
US5908621A
(en)
*
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
ES2615357T3
(es)
|
1996-12-06 |
2017-06-06 |
Amgen Inc. |
Terapia de combinación usando un inhibidor de IL-1 para tratar enfermedades mediadas por IL-1
|
ATE200030T1
(de)
*
|
1997-01-29 |
2001-04-15 |
Polymasc Pharmaceuticals Plc |
Pegylationsverfahren
|
ATE469166T1
(de)
|
1997-06-06 |
2010-06-15 |
Kyowa Hakko Kirin Co Ltd |
Chemisch modifizierte polypeptide
|
NZ502375A
(en)
*
|
1997-07-14 |
2001-11-30 |
Bolder Biotechnology Inc |
The addition of non-natural cysteine derivatives to cause the protein to act as antagonists of the GH family
|
US6753165B1
(en)
*
|
1999-01-14 |
2004-06-22 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
US20080076706A1
(en)
*
|
1997-07-14 |
2008-03-27 |
Bolder Biotechnology, Inc. |
Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
|
US6017876A
(en)
*
|
1997-08-15 |
2000-01-25 |
Amgen Inc. |
Chemical modification of granulocyte-colony stimulating factor (G-CSF) bioactivity
|
US5985263A
(en)
*
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
US5981709A
(en)
*
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
CA2330451A1
(en)
*
|
1998-04-28 |
1999-11-04 |
Applied Research Systems Ars Holding N.V. |
Polyol-ifn-beta conjugates
|
WO1999059621A1
(en)
*
|
1998-05-15 |
1999-11-25 |
Schering Corporation |
Combination therapy comprising ribavirin and interferon alpha in antiviral treatment naive patients having g chronic hepatitis c infection
|
NL1009601C2
(nl)
*
|
1998-07-09 |
2000-01-11 |
Univ Utrecht |
Verbinding welke de binding van een eiwit aan mestcellen kan remmen, toepassing van de verbinding voor de bereiding van een geneesmiddel, een farmaceutisch preparaat, een werkwijze voor het diagnostiseren van een ziekte en een selectiewerkwijze.
|
AU762392B2
(en)
*
|
1998-07-16 |
2003-06-26 |
Arca Biopharma, Inc. |
Methods and materials relating to novel CD39-like polypeptides
|
ES2245114T3
(es)
|
1998-08-06 |
2005-12-16 |
Mountain View Pharmaceuticals, Inc. |
Conjugados de peg-oxidasa de urato y su uso.
|
US6783965B1
(en)
*
|
2000-02-10 |
2004-08-31 |
Mountain View Pharmaceuticals, Inc. |
Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
|
US6420339B1
(en)
*
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
ES2265693T3
(es)
*
|
1998-10-16 |
2007-02-16 |
Biogen Idec Ma Inc. |
Proteinas de fusion con interferon-beta y usos.
|
ES2630278T3
(es)
*
|
1998-10-16 |
2017-08-21 |
Biogen Ma Inc. |
Conjugados poliméricos de interferón beta-1a y usos de los mismos
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
CN1810832B
(zh)
|
1998-10-23 |
2012-12-12 |
麒麟-安姆根有限公司 |
与MPl受体结合并具有血小板生成活性的模拟二聚体血小板生成素肽
|
EP1135493A2
(de)
*
|
1998-11-30 |
2001-09-26 |
Eli Lilly And Company |
Erythropoietische substanzen
|
US8288126B2
(en)
|
1999-01-14 |
2012-10-16 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
CN1210400C
(zh)
|
1999-01-14 |
2005-07-13 |
博尔德生物技术公司 |
制备含游离半胱氨酸残基的蛋白质的方法
|
SI1157037T1
(en)
*
|
1999-01-29 |
2003-12-31 |
F. Hoffmann-La Roche Ag |
Gcsf conjugates
|
ES2204509T3
(es)
*
|
1999-01-29 |
2004-05-01 |
F. Hoffmann-La Roche Ag |
Conjugados de gcsf.
|
AU2824700A
(en)
*
|
1999-03-01 |
2000-09-21 |
Kyowa Hakko Kogyo Co. Ltd. |
Chemically modified g-csf preparations
|
US6485718B1
(en)
*
|
1999-04-13 |
2002-11-26 |
Pharmacia Corporation |
Site specific ligation of proteins to synthetic particles
|
US6924264B1
(en)
*
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
US8106098B2
(en)
*
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
US6348558B1
(en)
|
1999-12-10 |
2002-02-19 |
Shearwater Corporation |
Hydrolytically degradable polymers and hydrogels made therefrom
|
US7074878B1
(en)
*
|
1999-12-10 |
2006-07-11 |
Harris J Milton |
Hydrolytically degradable polymers and hydrogels made therefrom
|
US6831158B2
(en)
*
|
2000-01-10 |
2004-12-14 |
Maxygen Holdings Ltd. |
G-CSF conjugates
|
US6555660B2
(en)
*
|
2000-01-10 |
2003-04-29 |
Maxygen Holdings Ltd. |
G-CSF conjugates
|
ES2327606T3
(es)
|
2000-01-10 |
2009-11-02 |
Maxygen Holdings Ltd |
Conjugados de g-csf.
|
US6646110B2
(en)
|
2000-01-10 |
2003-11-11 |
Maxygen Holdings Ltd. |
G-CSF polypeptides and conjugates
|
DE60138364D1
(de)
|
2000-02-11 |
2009-05-28 |
Bayer Healthcare Llc |
Gerinnungsfaktor vii oder viia konjugate
|
US7049761B2
(en)
*
|
2000-02-11 |
2006-05-23 |
Altair Engineering, Inc. |
Light tube and power supply circuit
|
CA2337661A1
(en)
|
2000-02-29 |
2001-08-29 |
Pfizer Products Inc. |
Stabilized granulocyte colony stimulating factor
|
US20020064820A1
(en)
*
|
2000-03-13 |
2002-05-30 |
Jean-Michel Dayer |
Apo-A-I regulation of T-cell signaling
|
AU2001289307A1
(en)
*
|
2000-04-06 |
2001-10-23 |
Pharmacia Corporation |
Chemically-modified myelopoietin conjugates
|
US6586398B1
(en)
*
|
2000-04-07 |
2003-07-01 |
Amgen, Inc. |
Chemically modified novel erythropoietin stimulating protein compositions and methods
|
US6939541B2
(en)
*
|
2000-04-14 |
2005-09-06 |
University Of South Carolina |
Cloning, overexpression and therapeutic use of bioactive histidine ammonia lyase
|
CA2407083A1
(en)
|
2000-04-21 |
2001-11-01 |
Amgen Inc. |
Apo-ai/aii peptide derivatives
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
US20030211094A1
(en)
|
2001-06-26 |
2003-11-13 |
Nelsestuen Gary L. |
High molecular weight derivatives of vitamin k-dependent polypeptides
|
KR20030032977A
(ko)
*
|
2000-07-12 |
2003-04-26 |
그리폰 테라퓨틱스, 인코포레이티드 |
키모카인 수용체 조절제, 제조 및 사용
|
RU2003109746A
(ru)
*
|
2000-09-08 |
2005-01-27 |
Грифон Терапьютикс, Инк. (Us) |
Синтетические белки, стимулирующие эритропоэз
|
US7118737B2
(en)
*
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
US7052686B2
(en)
*
|
2000-09-29 |
2006-05-30 |
Schering Corporation |
Pegylated interleukin-10
|
AU2001290312A1
(en)
*
|
2000-10-16 |
2002-04-29 |
Chugai Seiyaku Kabushiki Kaisha |
Peg-modified erythropoietin
|
CN1507357A
(zh)
*
|
2000-10-31 |
2004-06-23 |
PRҩƷ����˾ |
提高生物活性分子传递的方法和组合物
|
WO2002036626A1
(en)
*
|
2000-11-02 |
2002-05-10 |
Maxygen Aps |
Single-chain multimeric polypeptides
|
CN1321134C
(zh)
*
|
2000-11-23 |
2007-06-13 |
赵剑 |
一种生物活性蛋白质的非均一制品及其制备方法
|
BR0116206A
(pt)
*
|
2000-12-14 |
2003-12-23 |
Amylin Pharmaceuticals Inc |
Peptìdeo yy e agonistas de peptìdeo yy para tratamento de distúrbios metabólicos
|
US7053150B2
(en)
*
|
2000-12-18 |
2006-05-30 |
Nektar Therapeutics Al, Corporation |
Segmented polymers and their conjugates
|
TW593427B
(en)
*
|
2000-12-18 |
2004-06-21 |
Nektar Therapeutics Al Corp |
Synthesis of high molecular weight non-peptidic polymer derivatives
|
CN100528235C
(zh)
*
|
2000-12-20 |
2009-08-19 |
霍夫曼-拉罗奇有限公司 |
红细胞生成素共轭物
|
US7442370B2
(en)
|
2001-02-01 |
2008-10-28 |
Biogen Idec Ma Inc. |
Polymer conjugates of mutated neublastin
|
BR0207020A
(pt)
*
|
2001-02-06 |
2004-06-22 |
Merck Patent Ges Mit Beschaenk |
Fator de estimulação de colÈnia por granulócito (g-csf) modificado com imunogenicidade reduzida
|
EP1234583A1
(de)
*
|
2001-02-23 |
2002-08-28 |
F. Hoffmann-La Roche Ag |
PEG-Konjugate des HGF-NK4
|
YU48703A
(sh)
|
2001-02-27 |
2006-05-25 |
Maxygen Aps |
Novi interferonu beta-slični molekuli
|
US7276580B2
(en)
|
2001-03-12 |
2007-10-02 |
Biogen Idec Ma Inc. |
Neurotrophic factors
|
US20030203865A1
(en)
*
|
2001-04-30 |
2003-10-30 |
Pierrot Harvie |
Lipid-comprising drug delivery complexes and methods for their production
|
US7247618B2
(en)
*
|
2001-04-30 |
2007-07-24 |
Tripathi Rajavashisth |
Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
|
ES2527471T3
(es)
|
2001-05-11 |
2015-01-26 |
Amgen Inc. |
Péptidos y moléculas relacionadas que se unen a TALL-1
|
AU2002345938A1
(en)
*
|
2001-06-28 |
2003-03-03 |
Mountain View Pharmaceuticals, Inc. |
Polymer stabilized proteinases
|
NZ530545A
(en)
*
|
2001-07-11 |
2006-10-27 |
Maxygen Holdings Ltd |
Specific conjugates comprising a polypeptide exhibiting G-CSF activity and a non-polypeptide moiety
|
US20040077835A1
(en)
*
|
2001-07-12 |
2004-04-22 |
Robin Offord |
Chemokine receptor modulators, production and use
|
MXPA04003238A
(es)
*
|
2001-10-05 |
2004-07-08 |
Intermune Inc |
Metodo para tratar la infeccion de virus de hepatitis con una configuracion de suministro de interferon multifasica.
|
US7084257B2
(en)
|
2001-10-05 |
2006-08-01 |
Amgen Inc. |
Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
|
US6908963B2
(en)
*
|
2001-10-09 |
2005-06-21 |
Nektar Therapeutics Al, Corporation |
Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7157277B2
(en)
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7214660B2
(en)
*
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
EP2939696B1
(de)
|
2001-10-18 |
2016-03-09 |
Nektar Therapeutics |
Polymerkonjugate von opioid-antagonisten
|
WO2003043651A1
(en)
*
|
2001-11-19 |
2003-05-30 |
Kyowa Hakko Kogyo Co., Ltd. |
Drug mobilizing pluripotent stem cells from tissue into peripheral blood
|
US20030171285A1
(en)
*
|
2001-11-20 |
2003-09-11 |
Finn Rory F. |
Chemically-modified human growth hormone conjugates
|
KR20070072924A
(ko)
*
|
2001-11-20 |
2007-07-06 |
파마시아 코포레이션 |
화학적으로 개질된 인간 성장 호르몬 콘쥬게이트
|
KR100480432B1
(ko)
*
|
2001-12-04 |
2005-04-06 |
선바이오(주) |
G-csf와 폴리에틸렌글리콜 유도체의 배합체
|
WO2003049760A1
(en)
*
|
2001-12-07 |
2003-06-19 |
Intermune, Inc. |
Compositions and method for treating hepatitis virus infection
|
EP1468036B1
(de)
|
2002-01-14 |
2008-10-08 |
The General Hospital Corporation |
Bioabbaubare polyketale, verfahren zu ihrer herstellung sowie ihre verwendung
|
EA009783B1
(ru)
|
2002-01-18 |
2008-04-28 |
Байоджен Айдек Ма Инк. |
Полиалкиленгликоль с остатком для конъюгации биологически активного соединения
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
US20030191056A1
(en)
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
US20030199464A1
(en)
*
|
2002-04-23 |
2003-10-23 |
Silviu Itescu |
Regeneration of endogenous myocardial tissue by induction of neovascularization
|
ATE494002T1
(de)
*
|
2002-06-14 |
2011-01-15 |
Amylin Pharmaceuticals Inc |
Prävention und/oder behandlung von colitis ulcerosa mit pyy oder pyyä3-36ü
|
US20040002451A1
(en)
*
|
2002-06-20 |
2004-01-01 |
Bruce Kerwin |
Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
|
EP1534269B1
(de)
*
|
2002-07-19 |
2013-10-30 |
The General Hospital Corporation |
Oxim-konjugate und verfahren zu ihrer bildung und verwendung
|
WO2004009774A2
(en)
*
|
2002-07-19 |
2004-01-29 |
Amgen Inc. |
Protein conjugates with a water-soluble biocompatible, biogradable polymer
|
EP1545578A4
(de)
|
2002-08-28 |
2010-07-07 |
Immunex Corp |
Zusammensetzungen und verfahren zur behandlung von herz-kreislauf-erkrankungen
|
UA80838C2
(en)
*
|
2002-09-09 |
2007-11-12 |
|
Water-soluble polymer alkanals
|
US8129330B2
(en)
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
JP2004196770A
(ja)
*
|
2002-10-24 |
2004-07-15 |
Effector Cell Institute Inc |
樹状細胞前駆体の血中レベル上昇剤
|
US20050075279A1
(en)
*
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
US7314613B2
(en)
|
2002-11-18 |
2008-01-01 |
Maxygen, Inc. |
Interferon-alpha polypeptides and conjugates
|
TWI281864B
(en)
*
|
2002-11-20 |
2007-06-01 |
Pharmacia Corp |
N-terminally monopegylated human growth hormone conjugates and process for their preparation
|
AU2003292696A1
(en)
|
2002-12-26 |
2004-08-10 |
Takeda Pharmaceutical Company Limited |
Metastin derivative and use thereof
|
PL219741B1
(pl)
*
|
2002-12-26 |
2015-07-31 |
Mountain View Pharmaceuticals |
Sposób zwiększania antyproliferacyjnego potencjału nieglikozylowanego interferonu-beta-1b in vitro, koniugat wytworzony tym sposobem i jego zastosowanie oraz kompozycja farmaceutyczna zawierająca koniugat i jej zastosowanie
|
TWI364295B
(en)
|
2002-12-26 |
2012-05-21 |
Mountain View Pharmaceuticals |
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
|
WO2004061094A1
(en)
|
2002-12-30 |
2004-07-22 |
Gryphon Therapeutics, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
US7803362B2
(en)
*
|
2003-01-24 |
2010-09-28 |
Synageva Biopharma Corp. |
Glycosylated interferon alpha
|
WO2004076474A2
(en)
*
|
2003-02-26 |
2004-09-10 |
Intermune, Inc. |
Polyethylene glycol modified interferon compositions and methods of use thereof
|
US20070077225A1
(en)
*
|
2003-02-28 |
2007-04-05 |
Blatt Lawrence M |
Continuous delivery methods for treating hepatitis virus infection
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
CA2517145C
(en)
|
2003-03-05 |
2017-08-01 |
Halozyme, Inc. |
Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
KR20060003862A
(ko)
|
2003-03-14 |
2006-01-11 |
네오스 테크놀로지스, 인크. |
수용성분기폴리머 및 그 접합체
|
BRPI0408946A
(pt)
*
|
2003-03-28 |
2006-04-04 |
Biopolymed Inc |
material biologicamente ativo conjugado com polìmero biocompatìvel com complexo 1:1, seu processo de preparação e composição farmacêutica compreendendo o mesmo
|
US20060134736A1
(en)
*
|
2003-03-28 |
2006-06-22 |
Jacobs John W |
Human growth hormone conjugated with biocompatible polymer
|
US7642340B2
(en)
|
2003-03-31 |
2010-01-05 |
Xencor, Inc. |
PEGylated TNF-α variant proteins
|
AU2004227937B2
(en)
|
2003-03-31 |
2007-09-20 |
Xencor, Inc |
Methods for rational pegylation of proteins
|
US7610156B2
(en)
|
2003-03-31 |
2009-10-27 |
Xencor, Inc. |
Methods for rational pegylation of proteins
|
WO2006127896A2
(en)
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated factor ix
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US20070026485A1
(en)
|
2003-04-09 |
2007-02-01 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
AU2004229461A1
(en)
*
|
2003-04-11 |
2004-10-28 |
Pr Pharmaceuticals Inc. |
Method for preparation of site-specific protein conjugates
|
WO2004091517A2
(en)
|
2003-04-15 |
2004-10-28 |
Smithkline Beecham Corporation |
Conjugates comprising human il-18 and substitution mutants thereof
|
ATE433759T1
(de)
|
2003-04-18 |
2009-07-15 |
Biogen Idec Inc |
Polymerkonjugiertes glycosiliertes neublastin
|
WO2005016241A2
(en)
|
2003-05-16 |
2005-02-24 |
Intermune, Inc. |
Synthetic chemokine receptor ligands and methods of use thereof
|
EP1656410B1
(de)
|
2003-07-22 |
2010-03-10 |
Nektar Therapeutics |
Verfahren zur herstellung von funktionalisierten polymeren aus polymeralkoholen
|
CA2533512C
(en)
|
2003-07-25 |
2013-06-11 |
Amgen Inc. |
Antagonists and agonists of ldcam and methods of use
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
WO2005014655A2
(en)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
CN101880326B
(zh)
|
2003-08-25 |
2018-02-16 |
东丽株式会社 |
干扰素‑β复合物
|
GB0320638D0
(en)
|
2003-09-03 |
2003-10-01 |
Novartis Ag |
Organic compounds
|
PL1675622T3
(pl)
|
2003-09-17 |
2017-11-30 |
Nektar Therapeutics |
Proleki na bazie wieloramiennego polimeru
|
CA2536182C
(en)
*
|
2003-09-22 |
2012-07-24 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis c virus
|
SG143252A1
(en)
*
|
2003-10-09 |
2008-06-27 |
Ambrx Inc |
Polymer derivatives
|
EP1675871A2
(de)
|
2003-10-10 |
2006-07-05 |
Xencor Inc. |
Tnf-alpha-varianten auf proteinbasis zur behandlung von erkrankungen in verbindung mit tnf-alpha
|
CN102516386A
(zh)
|
2003-10-10 |
2012-06-27 |
诺沃挪第克公司 |
Il-21衍生物
|
RS20060259A
(en)
|
2003-10-14 |
2008-08-07 |
Intermune Inc., |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
EP2641611A3
(de)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Kombinationstherapie
|
US7407973B2
(en)
*
|
2003-10-24 |
2008-08-05 |
Intermune, Inc. |
Use of pirfenidone in therapeutic regimens
|
US7220407B2
(en)
*
|
2003-10-27 |
2007-05-22 |
Amgen Inc. |
G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
|
EP1725572B1
(de)
|
2003-11-05 |
2017-05-31 |
AGCT GmbH |
Makromolekulare nukleotidverbindungen und methoden zu deren anwendung
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20060040856A1
(en)
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
WO2005053730A1
(ja)
*
|
2003-12-05 |
2005-06-16 |
Kirin Beer Kabushiki Kaisha |
末期心不全治療剤
|
WO2005067963A1
(en)
*
|
2003-12-23 |
2005-07-28 |
Intermune, Inc. |
Use of polyethylene glycol-modified interferon-alpha in therapeutic dosing regimens
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
KR101439880B1
(ko)
|
2004-01-08 |
2014-09-12 |
라티오팜 게엠베하 |
펩티드의 오-결합형 글리코실화
|
ES2358333T3
(es)
*
|
2004-01-21 |
2011-05-09 |
Boehringer Ingelheim International Gmbh |
Péptidos macrocíclicos con acción contra el virus de la hepatitis c.
|
AU2005211362B2
(en)
|
2004-02-02 |
2008-03-13 |
Ambrx, Inc. |
Modified human interferon polypeptides and their uses
|
AU2005319099B2
(en)
|
2004-02-02 |
2010-09-16 |
Ambrx, Inc. |
Modified human growth hormone
|
WO2005077072A2
(en)
|
2004-02-11 |
2005-08-25 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
JP5638177B2
(ja)
*
|
2004-02-11 |
2014-12-10 |
アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc |
膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
JP2007526317A
(ja)
*
|
2004-03-01 |
2007-09-13 |
エンゾン ファーマスーティカルズ インコーポレイテッド |
インターフェロン−ベータ・ポリマー結合体
|
MXPA06010764A
(es)
*
|
2004-03-23 |
2006-12-15 |
Amgen Inc |
Metodos y composiciones de proteinas quimicamente modificadas.
|
WO2005115477A2
(en)
|
2004-04-13 |
2005-12-08 |
Quintessence Biosciences, Inc. |
Non-natural ribonuclease conjugates as cytotoxic agents
|
EP1586334A1
(de)
*
|
2004-04-15 |
2005-10-19 |
TRASTEC scpa |
G-CSF Konjugate mit PEG
|
CN101115769A
(zh)
|
2004-05-19 |
2008-01-30 |
马克西根公司 |
干扰素-α多肽和偶联物
|
WO2005123113A2
(en)
*
|
2004-06-14 |
2005-12-29 |
Intermune, Inc. |
Interferon compositions and methods of use thereof
|
CA2568952C
(en)
|
2004-06-18 |
2019-05-21 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
RU2006145886A
(ru)
|
2004-06-25 |
2008-06-27 |
Такеда Фармасьютикал Компани Лимитед (Jp) |
Производные метастина и их применение
|
WO2006004959A2
(en)
*
|
2004-06-30 |
2006-01-12 |
Egen Corporation |
Pegylated interferon alpha-1b
|
MX2007000216A
(es)
*
|
2004-07-08 |
2007-03-15 |
Amgen Inc |
Peptidos terapeuticos.
|
EP1771066A2
(de)
*
|
2004-07-13 |
2007-04-11 |
Neose Technologies, Inc. |
Remodellierung von verzweigtem peg und klykolysierung von glucagonähnlichem peptide-1 glp-1
|
MX2007000728A
(es)
|
2004-07-21 |
2007-03-15 |
Ambrx Inc |
Polipeptidos biosinteticos que utilizan amino acidos no naturalmente codificados.
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
CA2577755C
(en)
|
2004-08-19 |
2014-05-13 |
Biogen Idec Ma Inc. |
Neublastin variants
|
JP4959566B2
(ja)
|
2004-08-19 |
2012-06-27 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
トランスホーミング増殖因子βファミリータンパク質の折りたたみ
|
US8268967B2
(en)
|
2004-09-10 |
2012-09-18 |
Novo Nordisk A/S |
Glycopegylated interferon α
|
US20060204512A1
(en)
|
2004-09-23 |
2006-09-14 |
Vasgene Therapeutics, Inc. |
Polypeptide compounds for inhibiting angiogenesis and tumor growth
|
ES2572779T3
(es)
|
2004-10-29 |
2016-06-02 |
Ratiopharm Gmbh |
Remodelación y glucopegilación del Factor de Crecimiento de Fibroblastos (FGF)
|
AU2005306894B2
(en)
|
2004-11-05 |
2011-11-24 |
Northwestern University |
Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders
|
KR101272402B1
(ko)
|
2004-12-13 |
2013-06-10 |
아스트라제네카 파마수티컬스 엘피 |
췌장 폴리펩티드 족 모티프, 폴리펩티드 및 이를 포함하는방법
|
JP5425398B2
(ja)
|
2004-12-22 |
2014-02-26 |
アンブレツクス・インコーポレイテツド |
非天然アミノ酸及びポリペプチドを含む組成物、非天然アミノ酸及びポリペプチドに関連する方法並び非天然アミノ酸及びポリペプチドその使用
|
EP1674113A1
(de)
|
2004-12-22 |
2006-06-28 |
F. Hoffmann-La Roche Ag |
Konjugate von insulinähnlichem Wachstumfaktor-1 und Poly(Ethylenglykol)
|
JP4990792B2
(ja)
*
|
2004-12-22 |
2012-08-01 |
アンブレツクス・インコーポレイテツド |
アミノアシル−tRNAシンテターゼの組成物およびこの使用
|
EP1836316A4
(de)
|
2004-12-22 |
2009-07-22 |
Ambrx Inc |
Verfahren zur expression und reinigung von rekombinantem menschlichem wachstumshormon
|
NZ555386A
(en)
|
2004-12-22 |
2011-01-28 |
Ambrx Inc |
Formulations of human growth hormone comprising a non-naturally encoded amino acid
|
ES2449195T3
(es)
|
2005-01-10 |
2014-03-18 |
Ratiopharm Gmbh |
Factor estimulante de colonias de granulocitos glicopegilado
|
CA2595695A1
(en)
|
2005-01-25 |
2006-08-03 |
Cell Therapeutics, Inc. |
Biologically active protein conjugates comprising (nn[s/t]) peptide repeats and having increased plasma half-life
|
AU2005326226B2
(en)
*
|
2005-01-31 |
2010-11-11 |
Eci, Inc. |
Immunopotentiating agent
|
US7402730B1
(en)
|
2005-02-03 |
2008-07-22 |
Lexicon Pharmaceuticals, Inc. |
Knockout animals manifesting hyperlipidemia
|
WO2007022123A2
(en)
*
|
2005-08-11 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
EP2390264A1
(de)
*
|
2005-02-11 |
2011-11-30 |
Amylin Pharmaceuticals Inc. |
GIP-Analog und Hybridpolypeptide mit auswählbaren Eigenschaften
|
WO2006094530A1
(en)
*
|
2005-03-11 |
2006-09-14 |
Siegfried Ltd. |
Di-polymer protein conjugates and processes for their preparation
|
WO2007010552A2
(en)
*
|
2005-03-17 |
2007-01-25 |
Serum Institute Of India Limited |
N- terminal peg conjugate of erythropoietin
|
ATE480255T1
(de)
|
2005-03-31 |
2010-09-15 |
Amylin Pharmaceuticals Inc |
Zusammensetzungen und verfahren zur kontrolle, prävention und behandlung von essstörungen
|
JP2008534640A
(ja)
|
2005-04-05 |
2008-08-28 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
タンパク質の機能部位またはエピトープの遮蔽方法
|
EP2386571B1
(de)
|
2005-04-08 |
2016-06-01 |
ratiopharm GmbH |
Zusammensetzungen und Verfahren zur Herstellung von Glycosylierungsmutanten eines Proteaseresistenten menschlichen Wachstumshormons
|
PT3321359T
(pt)
|
2005-04-11 |
2021-03-11 |
Horizon Pharma Rheumatology Llc |
Formas variantes de urato-oxidase e a sua utilização
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
JP2008545393A
(ja)
|
2005-05-18 |
2008-12-18 |
マキシジェン, インコーポレイテッド |
進歩したインターフェロンαポリペプチド
|
BRPI0611221A2
(pt)
*
|
2005-06-01 |
2010-08-24 |
Maxygen Holdings Ltd |
polipeptÍdeos de g-csf peguilados e mÉtodos de produÇço dos mesmos
|
TW200722521A
(en)
*
|
2005-06-01 |
2007-06-16 |
Alza Corp |
Novel bioconjugation reactions for acylating polyethylene glycol reagents
|
WO2007009208A1
(en)
*
|
2005-06-02 |
2007-01-25 |
Cangene Corporation |
Poly(ethylene glocol) modified human gm-csf with increased biological activity
|
ATE529442T1
(de)
*
|
2005-06-03 |
2011-11-15 |
Ambrx Inc |
Verbesserte humane interferon-moleküle und ihre verwendungen
|
KR100694994B1
(ko)
*
|
2005-06-13 |
2007-03-14 |
씨제이 주식회사 |
사람 과립구 콜로니 형성인자 동종체
|
CA2611836A1
(en)
*
|
2005-06-13 |
2006-12-21 |
Nastech Pharmaceutical Company Inc. |
Transmucosal delivery of peptide derivatives
|
JP5335422B2
(ja)
|
2005-06-17 |
2013-11-06 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
少なくとも1つの非天然のシステインを含んでいる操作されたタンパク質の選択的な還元および誘導体化
|
KR20080033274A
(ko)
|
2005-06-17 |
2008-04-16 |
노파르티스 아게 |
Hcv에서 상글리페린의 용도
|
US7695710B2
(en)
*
|
2005-06-20 |
2010-04-13 |
Pepgen Corporation |
Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs
|
AU2006262151A1
(en)
*
|
2005-06-20 |
2007-01-04 |
Pepgen Corporation |
Low-toxicity, long-circulating chimeras of human interferon- alpha analogs and interferon tau
|
EP2412744B1
(de)
|
2005-07-18 |
2014-01-22 |
Nektar Therapeutics |
Verfahren zur Herstellung von verzweigten funktionalisierten Polymeren mithilfe von verzweigten Polyol-Kernen
|
KR100735784B1
(ko)
*
|
2005-07-20 |
2007-07-06 |
재단법인 목암생명공학연구소 |
인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물
|
EP2305695A3
(de)
|
2005-07-25 |
2011-07-27 |
Intermune, Inc. |
Makrocyclische Inhibitoren der Replikation des Hepatitis-C-Virus
|
CN101208386B
(zh)
*
|
2005-08-02 |
2012-07-18 |
第一毛织株式会社 |
一种用于封装半导体设备的环氧树脂组合物
|
JP2009503111A
(ja)
*
|
2005-08-04 |
2009-01-29 |
ネクター セラピューティックス エイエル,コーポレイション |
G−csf部分および重合体の複合体
|
BRPI0614649A2
(pt)
|
2005-08-11 |
2011-04-12 |
Amylin Pharmaceuticals Inc |
polipeptìdeos hìbridos com propriedades selecionáveis
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
CN103103238B
(zh)
|
2005-08-18 |
2016-08-10 |
Ambrx公司 |
一种在细胞中制造在特定位置处具有所选氨基酸的抗体或抗体片段多肽的方法
|
EP2347762B1
(de)
|
2005-08-19 |
2019-05-08 |
Amylin Pharmaceuticals, LLC |
Exendin zur diabetesbehandlung und gewichtsreducierung
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
BRPI0617274A2
(pt)
|
2005-10-11 |
2011-07-19 |
Intermune Inc |
compostos e métodos para a inibição de replicação viral de hepatite c
|
WO2007047303A2
(en)
*
|
2005-10-12 |
2007-04-26 |
Alvine Pharmaceuticals, Inc. |
Pegylated glutenase polypeptides
|
KR20140077946A
(ko)
|
2005-10-13 |
2014-06-24 |
휴먼 게놈 사이언시즈, 인코포레이티드 |
자가항체 양성 질환 환자의 치료에 유용한 방법 및 조성물
|
US8168592B2
(en)
*
|
2005-10-21 |
2012-05-01 |
Amgen Inc. |
CGRP peptide antagonists and conjugates
|
US20080171696A1
(en)
*
|
2005-10-21 |
2008-07-17 |
Avigenics, Inc. |
Pharmacodynamically enhanced therapeutic proteins
|
US20070092486A1
(en)
*
|
2005-10-21 |
2007-04-26 |
Avigenics, Inc. |
Glycolated and glycosylated poultry derived therapeutic proteins
|
US20090048440A1
(en)
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
AU2006311568B2
(en)
*
|
2005-11-08 |
2010-11-11 |
Ambrx, Inc. |
Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
EP1951890A4
(de)
*
|
2005-11-16 |
2009-06-24 |
Ambrx Inc |
Verfahren und zusammensetzungen mit nichtnatürlichen aminosäuren
|
DK1968635T3
(en)
*
|
2005-12-14 |
2014-12-15 |
Ambrx Inc |
Compositions and Methods of, and uses of non-natural amino acids and polypeptides
|
US8404643B2
(en)
|
2005-12-22 |
2013-03-26 |
Takeda Pharmaceutical Company Limited |
Metastin derivatives and use thereof
|
EP1981525B1
(de)
|
2005-12-30 |
2015-01-21 |
Zensun (Shanghai) Science and Technology Limited |
Verlängerte freisetzung von neuregulin für verbesserte herzfunktion
|
DK1985303T3
(da)
|
2006-01-12 |
2013-02-25 |
Kitasato Daiichi Sankyo Vaccine Co Ltd |
Oral sammensætning indeholdende interferon-alpha
|
CN100475270C
(zh)
*
|
2006-01-20 |
2009-04-08 |
清华大学 |
一种治疗肿瘤的药物及其应用
|
TW200738752A
(en)
|
2006-01-31 |
2007-10-16 |
Bayer Schering Pharma Ag |
Modulation of MDL-1 activity for treatment of inflammatory disease
|
EP2319542B1
(de)
|
2006-02-21 |
2018-03-21 |
Nektar Therapeutics |
Segmentierte abbaubare Polymere und daraus hergestellte Konjugate
|
TWI501774B
(zh)
|
2006-02-27 |
2015-10-01 |
Biogen Idec Inc |
神經性病症之治療
|
EP2010569A4
(de)
|
2006-03-20 |
2009-09-09 |
Xoma Technology Ltd |
Für gastrin spezifische humane antikörper, materialien und methoden
|
CA2648053A1
(en)
*
|
2006-03-31 |
2007-10-11 |
Centocor, Inc. |
Binding partners with immunoglobulin domains modified to have extended half-life
|
CN101466727B
(zh)
|
2006-04-11 |
2012-10-17 |
诺瓦提斯公司 |
Hcv/hiv抑制剂及其用途
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
EP2029160A2
(de)
*
|
2006-05-12 |
2009-03-04 |
Amylin Pharmaceuticals, Inc. |
Verfahren zur wiederherstellung der glykämischen kontrolle
|
EP2032600A2
(de)
|
2006-05-19 |
2009-03-11 |
Glycofi, Inc. |
Erythropoietinzusammensetzungen
|
EP2213733A3
(de)
|
2006-05-24 |
2010-12-29 |
Novo Nordisk Health Care AG |
Analoge des Faktor IX mit verlängerter Halbwertszeit in vivo
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
WO2007149594A2
(en)
|
2006-06-23 |
2007-12-27 |
Quintessence Biosciences, Inc. |
Modified ribonucleases
|
EP2452683A3
(de)
|
2006-06-26 |
2012-08-22 |
Amgen Inc. |
Verfahren zur Behandlung von Atherosklerose
|
US8298801B2
(en)
*
|
2006-07-17 |
2012-10-30 |
Quintessence Biosciences, Inc. |
Methods and compositions for the treatment of cancer
|
US9187532B2
(en)
|
2006-07-21 |
2015-11-17 |
Novo Nordisk A/S |
Glycosylation of peptides via O-linked glycosylation sequences
|
US8394921B2
(en)
|
2006-07-25 |
2013-03-12 |
Lipoxen Technologies Limited |
N-terminal derivatisation of proteins with polysaccharides
|
GB0615067D0
(en)
*
|
2006-07-28 |
2006-09-06 |
Ttp Communications Ltd |
Reconfigurable signal processing scheme
|
CA2659990C
(en)
*
|
2006-08-04 |
2016-03-22 |
Prolong Pharmaceuticals, Inc. |
Polyethylene glycol erythropoietin conjugates
|
ITMI20061624A1
(it)
*
|
2006-08-11 |
2008-02-12 |
Bioker Srl |
Mono-coniugati sito-specifici di g-csf
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
CL2007002502A1
(es)
|
2006-08-31 |
2008-05-30 |
Hoffmann La Roche |
Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer.
|
KR101106795B1
(ko)
*
|
2006-08-31 |
2012-01-18 |
에프. 호프만-라 로슈 아게 |
인슐린-유사 성장 인자-i의 제조 방법
|
EP2615108B1
(de)
*
|
2006-09-08 |
2016-10-26 |
Ambrx, Inc. |
Modifiziertes humanes Plasmapolypeptid oder Fc-Gerüste und deren Verwendungen
|
DK2061878T3
(da)
*
|
2006-09-08 |
2014-04-07 |
Ambrx Inc |
Hybridsuppressor-trna for hvirveldyrceller
|
MX2009002526A
(es)
*
|
2006-09-08 |
2009-04-16 |
Ambrx Inc |
Transcripcion de tarn supresor en celulas de vertebrados.
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
NZ597098A
(en)
|
2006-09-28 |
2013-05-31 |
Merck Sharp & Dohme |
Use of pegylated il-10 to treat cancer
|
EP2054521A4
(de)
|
2006-10-03 |
2012-12-19 |
Novo Nordisk As |
Verfahren zur reinigung von polypeptid-konjugate
|
JP5457185B2
(ja)
*
|
2006-10-04 |
2014-04-02 |
ノヴォ ノルディスク アー/エス |
グリセロール連結のpeg化された糖および糖ペプチド
|
WO2008051383A2
(en)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Use of alcohol co-solvents to improve pegylation reaction yields
|
JO3048B1
(ar)
|
2006-10-25 |
2016-09-05 |
Takeda Pharmaceuticals Co |
مشتقات متاستين واستخدامها
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
KR101079993B1
(ko)
*
|
2006-11-17 |
2011-11-04 |
동아제약주식회사 |
폴리에틸렌글리콜 과립구 콜로니 자극인자 접합체
|
AU2007325838B2
(en)
|
2006-11-22 |
2013-09-19 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR
|
PT2121751T
(pt)
|
2006-12-08 |
2017-04-18 |
Lexicon Pharmaceuticals Inc |
Anticorpos monoclonais contra angptl3
|
US20100144599A1
(en)
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
CN101245109B
(zh)
*
|
2007-02-12 |
2011-12-14 |
杭州九源基因工程有限公司 |
一种聚乙二醇单修饰的重组人粒细胞集落刺激因子突变体及其制备方法
|
ATE554785T1
(de)
|
2007-03-30 |
2012-05-15 |
Ambrx Inc |
Modifizierte fgf-21 polypeptide und ihre verwendung
|
CA2682897C
(en)
|
2007-04-03 |
2016-11-22 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
JP2008266219A
(ja)
*
|
2007-04-20 |
2008-11-06 |
National Institute Of Advanced Industrial & Technology |
リジン及びシステイン残基を含まないタンパク質
|
US8329655B2
(en)
|
2007-05-01 |
2012-12-11 |
Biogen Idec Ma Inc. |
Methods for increasing vascularization
|
WO2008137471A2
(en)
|
2007-05-02 |
2008-11-13 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
MX2009012609A
(es)
|
2007-05-22 |
2009-12-07 |
Amgen Inc |
Composiciones y metodos para producir proteinas de fusion bioactivas.
|
EP2162535A4
(de)
*
|
2007-06-04 |
2011-02-23 |
Novo Nordisk As |
O-verknüpfte glykosylierung unter verwendung von n-acetylglucosaminyl-transferasen
|
CN101778859B
(zh)
|
2007-06-12 |
2014-03-26 |
诺和诺德公司 |
改良的用于生产核苷酸糖的方法
|
WO2009003188A2
(en)
*
|
2007-06-27 |
2008-12-31 |
Cedars-Sinai Medical Center |
N-terminal specific chemical labeling for proteomics applications
|
KR20100040937A
(ko)
|
2007-07-26 |
2010-04-21 |
암젠 인크 |
변형된 레시틴-콜레스테롤 아실트랜스퍼라제 효소
|
CN101352573B
(zh)
*
|
2007-07-27 |
2011-02-09 |
杭州九源基因工程有限公司 |
聚乙二醇单修饰的重组人集落细胞刺激因子赖氨酸缺陷体
|
WO2009023566A2
(en)
|
2007-08-09 |
2009-02-19 |
Genzyme Corporation |
Method of treating autoimmune disease with mesenchymal stem cells
|
CL2008002399A1
(es)
*
|
2007-08-16 |
2009-01-02 |
Pharmaessentia Corp |
Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c.
|
CN104689333B
(zh)
|
2007-08-27 |
2018-05-29 |
拉蒂奥法姆有限责任公司 |
G-csf 缀合物的液体制剂
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
WO2009046015A2
(en)
*
|
2007-09-30 |
2009-04-09 |
University Of Florida Research Foundation, Inc. |
Combination therapies for treating type 1 diabetes
|
EP2205271B1
(de)
*
|
2007-10-08 |
2014-05-21 |
Quintessence Biosciences, Inc. |
Zusammensetzungen und verfahren für therapien auf ribonukleasebasis
|
EP2214716B1
(de)
|
2007-10-23 |
2021-11-17 |
Nektar Therapeutics |
Auf hydroxyapatite gezielrichtete multiarm polymere und daraus hergestellte konjugate
|
EP2930182A1
(de)
|
2007-11-20 |
2015-10-14 |
Ambrx, Inc. |
Modifizierte insulinpolypeptide und deren verwendungen
|
CA2707979A1
(en)
*
|
2007-12-13 |
2009-06-18 |
Biovectra Inc. |
Polypeptides modified by protein trans-splicing technology
|
EP2245456B1
(de)
*
|
2007-12-27 |
2013-02-13 |
Baxter International Inc. |
Verfahren und zusammensetzungen zum spezifischen nachweis physiologisch unbedenklicher polymermoleküle
|
JP5647899B2
(ja)
*
|
2008-01-08 |
2015-01-07 |
ラツィオファルム ゲーエムベーハーratiopharm GmbH |
オリゴサッカリルトランスフェラーゼを使用するポリペプチドの複合糖質化
|
WO2009120396A2
(en)
*
|
2008-01-08 |
2009-10-01 |
The University Of California |
Compositions and methods for regulating erythropoientin expression and ameliorating anemia and stimulating erythropoiesis
|
US20090183503A1
(en)
*
|
2008-01-18 |
2009-07-23 |
Alberto Verdesi |
Exhaust apparatus
|
CA2711590C
(en)
|
2008-01-18 |
2021-03-23 |
Biomarin Pharmaceutical Inc. |
Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
|
SG188143A1
(en)
|
2008-02-08 |
2013-03-28 |
Ambrx Inc |
Modified leptin polypeptides and their uses
|
US8629104B2
(en)
|
2008-02-18 |
2014-01-14 |
Jiangsu Hengrui Medicine Co. Ltd. |
G-CSF and water-soluble polymer conjugate
|
US20130189239A1
(en)
|
2008-02-27 |
2013-07-25 |
Novo Nordisk A/S |
Conjugated Factor VIII Molecules
|
TWI395593B
(zh)
|
2008-03-06 |
2013-05-11 |
Halozyme Inc |
可活化的基質降解酵素之活體內暫時性控制
|
AU2008353850B2
(en)
|
2008-04-03 |
2014-08-21 |
Biosteed Gene Expression Tech. Co., Ltd. |
Double-stranded polyethylene glycol modified growth hormone, preparation method and application thereof
|
CA2720478A1
(en)
*
|
2008-04-03 |
2009-10-08 |
F. Hoffmann-La Roche Ag |
Pegylated insulin-like-growth-factor assay
|
SG187427A1
(en)
|
2008-04-14 |
2013-02-28 |
Halozyme Inc |
Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
|
TWI394580B
(zh)
|
2008-04-28 |
2013-05-01 |
Halozyme Inc |
超快起作用胰島素組成物
|
US20110263496A1
(en)
|
2008-05-21 |
2011-10-27 |
Amylin Pharmaceuticals, Inc. |
Exendins to lower cholesterol and triglycerides
|
AR071874A1
(es)
|
2008-05-22 |
2010-07-21 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
GB0811743D0
(en)
|
2008-06-26 |
2008-07-30 |
Hemosol Biopharma Inc |
Composition
|
EP2671891A3
(de)
|
2008-06-27 |
2014-03-05 |
Amgen Inc. |
Ang-2-Hemmung zur Behandlung von Multipler Sklerose
|
US10138283B2
(en)
|
2008-07-23 |
2018-11-27 |
Ambrx, Inc. |
Modified bovine G-CSF polypeptides and their uses
|
EP2314609B1
(de)
*
|
2008-07-30 |
2016-11-30 |
Takeda Pharmaceutical Company Limited |
Metastinderivat und verwendung davon
|
JP5639585B2
(ja)
*
|
2008-07-31 |
2014-12-10 |
ファーマエッセンティア コーポレイション |
ペプチド−ポリマー共役体
|
KR101671537B1
(ko)
|
2008-08-11 |
2016-11-01 |
넥타르 테라퓨틱스 |
다분지형 중합체 알카노에이트 컨쥬게이트
|
WO2010030366A2
(en)
|
2008-09-11 |
2010-03-18 |
Nektar Therapeutics |
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method
|
CN102232085A
(zh)
|
2008-09-26 |
2011-11-02 |
Ambrx公司 |
修饰的动物促红细胞生成素多肽和其用途
|
MX2011003196A
(es)
|
2008-09-26 |
2011-04-27 |
Ambrx Inc |
Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales.
|
BRPI0920743A2
(pt)
|
2008-10-01 |
2016-09-20 |
Quintessence Biosciences Inc |
ribonucleases terapeuticas
|
EA032727B1
(ru)
|
2008-10-10 |
2019-07-31 |
Амген Инк. |
Мутантный резистентный к протеолизу полипептид fgf21 и его применение
|
ES2441941T3
(es)
|
2008-10-15 |
2014-02-07 |
Baxter Healthcare Sa |
Pegilación de factores de coagulación sanguínea recombinantes en presencia de anticuerpos enlazados
|
WO2010045568A1
(en)
*
|
2008-10-17 |
2010-04-22 |
Baxter International Inc. |
Modified blood factors comprising a low degree of water soluble polymer
|
BRPI0919827B8
(pt)
*
|
2008-10-20 |
2021-05-25 |
Usv Ltd |
processos para aumentar o rendimento de uma reação de peguilação de r-methug-csf processo para a produção em escala grama de peg- r-methug-csf
|
WO2010048184A2
(en)
|
2008-10-21 |
2010-04-29 |
Baxter International Inc. |
Methods for determining active ingredients in pro-drug peg protein conjugates with releasable peg reagents (in vitro de-pegylation)
|
EP2344527A4
(de)
*
|
2008-10-31 |
2012-04-04 |
Amgen Inc |
Materialien und verfahren für stammzellenmobilisierung durch einen mehrfach pegylierten granulozyten-kolonie-stimulierenden faktor
|
IT1392655B1
(it)
|
2008-11-20 |
2012-03-16 |
Bio Ker S R L |
Site-specific monoconjugated insulinotropic glp-1 peptides.
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之egfr/igfir結合分子
|
KR101546563B1
(ko)
|
2008-12-09 |
2015-08-28 |
할로자임, 아이엔씨 |
연장된 가용성 ph20 폴리펩티드 및 그의 용도
|
CA2746125C
(en)
*
|
2008-12-11 |
2017-07-11 |
Baxter International Inc. |
Detection of physiologically acceptable polymer molecules using near infrared spectroscopy
|
HUE037936T2
(hu)
|
2008-12-17 |
2018-09-28 |
Merck Sharp & Dohme |
Mono- és di-pegil IL-10 elõállítása és alkalmazása
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
HRP20240135T1
(hr)
|
2009-05-05 |
2024-04-12 |
Amgen Inc. |
Fgf21 mutanti i njihove upotrebe
|
US20120052069A1
(en)
|
2009-05-05 |
2012-03-01 |
Amgen Inc |
Fgf21 mutants and uses thereof
|
MX2011012277A
(es)
*
|
2009-05-20 |
2011-12-12 |
Biomarin Pharm Inc |
Variantes de peptidos natriureticos de tipo c.
|
WO2010148142A1
(en)
|
2009-06-17 |
2010-12-23 |
Amgen Inc. |
Chimeric fgf19 polypeptides and uses thereof
|
SG176922A1
(en)
|
2009-06-19 |
2012-01-30 |
Medimmune Llc |
Protease variants
|
SG10201408480RA
(en)
|
2009-06-25 |
2015-02-27 |
Crealta Pharmaceuticals Llc |
Methods for preventing or predicting infusion reactions or antibody-mediated loss of response, by monitoring serum uric acid levels during pegylated uricase therapy
|
WO2011014882A1
(en)
|
2009-07-31 |
2011-02-03 |
Medtronic, Inc. |
CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS
|
IN2012DN03219A
(de)
|
2009-09-17 |
2015-10-23 |
Baxter Healthcare Sa |
|
US20120178914A1
(en)
*
|
2009-09-25 |
2012-07-12 |
Vybion, Inc. |
Polypeptide modification
|
US9885711B2
(en)
|
2009-09-25 |
2018-02-06 |
Xoma Technology Ltd. |
Screening methods
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
WO2011050938A1
(de)
|
2009-10-26 |
2011-05-05 |
Genovoxx Gmbh |
Konjugate von nukleotiden und methoden zu deren anwendung
|
KR20120106942A
(ko)
|
2009-10-30 |
2012-09-27 |
베링거 인겔하임 인터내셔날 게엠베하 |
Bi201335, 인터페론 알파 및 리바비린을 포함하는 hcv 병용 치료요법을 위한 투여 용법
|
CA2778678A1
(en)
|
2009-10-30 |
2011-05-05 |
Cns Therapeutics, Inc. |
Improved neurturin molecules
|
WO2011063414A1
(en)
|
2009-11-23 |
2011-05-26 |
Amylin Pharmaceuticals, Inc. |
Polypeptide conjugate
|
EP2507381A4
(de)
|
2009-12-04 |
2016-07-20 |
Hoffmann La Roche |
Multispezifische antikörper, antikörperanaloge, zusammensetzungen und verfahren
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
BR112012015597A2
(pt)
|
2009-12-21 |
2017-01-31 |
Ambrx Inc |
peptídeos de somatotropina suínos modificados e seus usos
|
MX349301B
(es)
|
2009-12-21 |
2017-07-21 |
Ambrx Inc |
Polipéptidos de somatotropina bovina modificados y sus usos.
|
US20110152188A1
(en)
*
|
2009-12-23 |
2011-06-23 |
Hanns-Christian Mahler |
Pharmaceutical compositions of igf/i proteins
|
WO2011101242A1
(en)
|
2010-02-16 |
2011-08-25 |
Novo Nordisk A/S |
Factor viii molecules with reduced vwf binding
|
JP5840148B2
(ja)
*
|
2010-03-04 |
2016-01-06 |
フェニックス インク. |
変性させることなく可溶性組換えインターフェロンタンパク質を産生する方法
|
NZ603033A
(en)
|
2010-04-01 |
2014-06-27 |
Pfenex Inc |
Methods for g-csf production in a pseudomonas host cell
|
AU2011239689A1
(en)
|
2010-04-15 |
2012-11-08 |
Amgen Inc. |
Human FGF receptor and beta-Klotho binding proteins
|
AU2011248625B2
(en)
|
2010-04-26 |
2017-01-05 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
|
JP6294074B2
(ja)
|
2010-04-27 |
2018-03-14 |
エータイアー ファーマ, インコーポレイテッド |
イソロイシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
WO2011139853A2
(en)
|
2010-04-28 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
|
CA2797393C
(en)
|
2010-04-29 |
2020-03-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
|
US9068177B2
(en)
|
2010-04-29 |
2015-06-30 |
Atyr Pharma, Inc |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
|
CA2797374C
(en)
|
2010-04-29 |
2021-02-16 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
|
CN102234310B
(zh)
*
|
2010-04-30 |
2017-02-08 |
杭州九源基因工程有限公司 |
一种聚乙二醇修饰蛋白的分离纯化方法
|
CA2797978C
(en)
|
2010-05-03 |
2019-12-03 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases
|
CN103096925A
(zh)
|
2010-05-03 |
2013-05-08 |
Atyr医药公司 |
与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
CN103096912A
(zh)
|
2010-05-03 |
2013-05-08 |
Atyr医药公司 |
与苯丙氨酰-α-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
CN102985103A
(zh)
|
2010-05-04 |
2013-03-20 |
Atyr医药公司 |
与p38多-tRNA合成酶复合物相关的治疗、诊断和抗体组合物的创新发现
|
WO2011143274A1
(en)
|
2010-05-10 |
2011-11-17 |
Perseid Therapeutics |
Polypeptide inhibitors of vla4
|
JP6396656B2
(ja)
|
2010-05-14 |
2018-09-26 |
エータイアー ファーマ, インコーポレイテッド |
フェニルアラニルβtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
JP6027965B2
(ja)
|
2010-05-17 |
2016-11-16 |
エータイアー ファーマ, インコーポレイテッド |
ロイシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
MX2012013375A
(es)
|
2010-05-17 |
2013-04-11 |
Cebix Inc |
Peptido c pegilado.
|
ES2573108T3
(es)
|
2010-05-26 |
2016-06-06 |
Bristol-Myers Squibb Company |
Proteínas de armazón a base de fibronectina que tienen estabilidad mejorada
|
US8962560B2
(en)
|
2010-06-01 |
2015-02-24 |
Atyr Pharma Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Lysyl-tRNA synthetases
|
WO2011159930A2
(en)
|
2010-06-16 |
2011-12-22 |
Medtronic, Inc. |
Damping systems for stabilizing medications in drug delivery devices
|
AU2011268498A1
(en)
|
2010-06-24 |
2013-01-31 |
Genoscience Pharma Sas |
Treatment of hepatitis C virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent
|
CA2804416C
(en)
|
2010-07-12 |
2020-04-28 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
|
EP2593130A2
(de)
|
2010-07-15 |
2013-05-22 |
Novo Nordisk A/S |
Stabilisierte faktor-viii-varianten
|
EP2595624B1
(de)
|
2010-07-20 |
2018-01-31 |
Halozyme, Inc. |
Verfahren zur linderung bzw. vermeidung der nebenwirkungen im zusammenhang mit der verabreichung eines anti-hyaluronan-mittels
|
AR082319A1
(es)
|
2010-07-22 |
2012-11-28 |
Biomarin Pharm Inc |
Produccion de una n-acetilgalactosamina-6-sulfatasa humana activa altamente fosforilada y sus usos
|
EP3578205A1
(de)
|
2010-08-06 |
2019-12-11 |
ModernaTX, Inc. |
Pharmazeutische zusammensetzungen enthaltenbearbeitete nukleinsäuren und ihre medizinische verwendung
|
RU2446173C1
(ru)
*
|
2010-08-13 |
2012-03-27 |
Зао "Биокад" |
Новый функционально активный, высокоочищенный стабильный конъюгат гранулоцитарного колониестимулирующего фактора (г-ксф) с полиэтиленгликолем с пролонгированным биологическим действием, пригодный для медицинского применения, и иммунобиологическое средство на его основе
|
HUE045845T2
(hu)
|
2010-08-17 |
2021-12-28 |
Ambrx Inc |
Módosított relaxin polipeptidek és felhasználásuk
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
AU2011293294B2
(en)
|
2010-08-25 |
2016-03-24 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Tyrosyl-tRNA synthetases
|
EP3466968A1
(de)
|
2010-09-15 |
2019-04-10 |
Stichting Sanquin Bloedvoorziening |
Faktor-viii-varianten mit reduzierter zellulärer aufnahme
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
ES2641869T3
(es)
|
2010-09-28 |
2017-11-14 |
Aegerion Pharmaceuticals, Inc. |
Polipéptidos de fusión de leptina-ABD con duración de acción aumentada
|
AU2011311706B2
(en)
|
2010-10-05 |
2015-11-12 |
Debiopharm S.A. |
New treatments of Hepatitis C virus infection
|
AU2011311880B2
(en)
|
2010-10-08 |
2014-07-24 |
Novartis Ag |
Vitamin E formulations of sulfamide NS3 inhibitors
|
CN102453089B
(zh)
*
|
2010-10-25 |
2014-06-04 |
北京凯因科技股份有限公司 |
重组集成干扰素变异体聚乙二醇偶联物的制备和应用
|
CN103933577B
(zh)
*
|
2010-10-25 |
2014-12-10 |
北京凯因科技股份有限公司 |
重组集成干扰素变异体聚乙二醇偶联物的制备和应用
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
RU2013123793A
(ru)
|
2010-11-24 |
2014-12-27 |
Лексикон Фармасьютикалз, Инк. |
Антитела, связывающиеся с notum пектинацетилэстеразой
|
WO2012072655A1
(en)
|
2010-11-30 |
2012-06-07 |
Novartis Ag |
New treatments of hepatitis c virus infection
|
CN102485742A
(zh)
*
|
2010-12-02 |
2012-06-06 |
山东新时代药业有限公司 |
一种聚乙二醇单修饰的重组人粒细胞集落刺激因子的制备及分离纯化方法
|
US20140371258A1
(en)
|
2010-12-17 |
2014-12-18 |
Nektar Therapeutics |
Water-Soluble Polymer Conjugates of Topotecan
|
US10736969B2
(en)
|
2010-12-21 |
2020-08-11 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of pemetrexed-based compounds
|
US20130331443A1
(en)
|
2010-12-22 |
2013-12-12 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of taxane-based compounds
|
US10894087B2
(en)
|
2010-12-22 |
2021-01-19 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
|
EP2672958A1
(de)
|
2011-02-08 |
2013-12-18 |
Halozyme, Inc. |
Zusammensetzung und lipidformulierung eines hyaluronan-abbauenden enzym und seine verwendung zur behandlung von benigner prostatahyperplasie
|
CN103930437A
(zh)
|
2011-03-16 |
2014-07-16 |
安姆根有限公司 |
Nav1.3和Nav1.7的强效及选择性抑制剂
|
EP2688584A4
(de)
*
|
2011-03-25 |
2015-05-20 |
Univ Columbia |
Pegylierte menschliche hdl-partikel und verfahren zu ihrer herstellung
|
CN103476409A
(zh)
|
2011-03-31 |
2013-12-25 |
诺华股份有限公司 |
治疗丙肝病毒感染的阿拉泊韦
|
KR20140010097A
(ko)
|
2011-04-01 |
2014-01-23 |
노파르티스 아게 |
B형 간염 바이러스 단독 감염 또는 델타 간염 바이러스와의 조합 감염 및 연관된 간 질환의 치료
|
CN103648516A
(zh)
|
2011-04-13 |
2014-03-19 |
诺华股份有限公司 |
使用阿拉泊韦治疗丙型肝炎病毒感染
|
EP2709669A1
(de)
|
2011-05-17 |
2014-03-26 |
Bristol-Myers Squibb Company |
Verfahren zur aufrechterhaltung der pegylierung von polypeptiden
|
SG10201902706VA
(en)
|
2011-06-03 |
2019-04-29 |
Xoma Technology Ltd |
Antibodies specific for tgf-beta
|
EP2720713A2
(de)
|
2011-06-17 |
2014-04-23 |
Halozyme, Inc. |
Kontinuierliches subkutanes insulininfusionsverfahren mit einem hyaluronanabbauenden enzym
|
US9993529B2
(en)
|
2011-06-17 |
2018-06-12 |
Halozyme, Inc. |
Stable formulations of a hyaluronan-degrading enzyme
|
US20130090294A1
(en)
|
2011-06-28 |
2013-04-11 |
Alternative Innovative Technologies Llc |
Novel methods of use of hsp70 for increased performance or treatment of hsp70 related disorders
|
CA2840552A1
(en)
|
2011-07-01 |
2013-01-10 |
Bayer Intellectual Property Gmbh |
Relaxin fusion polypeptides and uses thereof
|
AU2012278944B2
(en)
|
2011-07-05 |
2015-09-17 |
Bioasis Technologies Inc. |
p97-antibody conjugates and methods of use
|
CN103957926B
(zh)
|
2011-07-08 |
2018-07-03 |
安米林药品有限责任公司 |
具有增强的作用持续时间和降低的免疫原性的工程改造的多肽
|
CN102952067A
(zh)
*
|
2011-08-30 |
2013-03-06 |
苏州欣诺科生物科技有限公司 |
用于蛋白质n端聚乙二醇修饰的吡哆醛衍生物、制备方法及其应用
|
US20140213512A1
(en)
|
2011-08-31 |
2014-07-31 |
Amgen Inc. |
Method of Treating or Ameliorating Type 1 Diabetes Using FGF21
|
US20130071394A1
(en)
|
2011-09-16 |
2013-03-21 |
John K. Troyer |
Compositions and combinations of organophosphorus bioscavengers and hyaluronan-degrading enzymes, and methods of use
|
US9006400B2
(en)
|
2011-09-26 |
2015-04-14 |
Novartis Ag |
Fibroblast growth factor-21-Fc fusion proteins
|
TW201315742A
(zh)
|
2011-09-26 |
2013-04-16 |
Novartis Ag |
治療代謝病症之雙功能蛋白質
|
WO2013045460A1
(en)
|
2011-09-27 |
2013-04-04 |
Novartis Ag |
Alisporivr for treatment of hepatis c virus infection
|
US9937241B2
(en)
|
2011-10-14 |
2018-04-10 |
Alternative Innovative Technologies Llc |
Degradation resistant HSP70 formulations and uses thereof
|
SG11201401797TA
(en)
|
2011-10-24 |
2014-09-26 |
Halozyme Inc |
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
|
EP2771296B1
(de)
|
2011-10-25 |
2017-09-27 |
Corning Incorporated |
Pharmazeutische delaminationsresistente glasbehälter mit pharmazeutischen wirkstoffen
|
US10350139B2
(en)
|
2011-10-25 |
2019-07-16 |
Corning Incorporated |
Pharmaceutical glass packaging assuring pharmaceutical sterility
|
US9522951B2
(en)
|
2011-10-31 |
2016-12-20 |
Bristol-Myers Squibb Company |
Fibronectin binding domains with reduced immunogenicity
|
WO2013075117A2
(en)
|
2011-11-17 |
2013-05-23 |
John Wahren |
Pegylated c-peptide
|
WO2013101509A2
(en)
|
2011-12-15 |
2013-07-04 |
Alternative Innovative Technologies Llc |
Hsp70 fusion protein conjugates and uses thereof
|
PT3130347T
(pt)
|
2011-12-30 |
2019-12-10 |
Halozyme Inc |
Variantes de polipéptidos de ph20, suas formulações e utilizações
|
EP2809350B1
(de)
|
2012-01-30 |
2018-10-17 |
Arecor Limited |
Stabilisierte wässrige antikörperzusammensetzungen
|
RU2659423C2
(ru)
|
2012-02-16 |
2018-07-02 |
ЭйТИР ФАРМА, ИНК. |
ГИСТИДИЛ-тРНК-СИНТЕТАЗЫ ДЛЯ ЛЕЧЕНИЯ АУТОИММУННЫХ И ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ
|
WO2013130684A1
(en)
|
2012-02-27 |
2013-09-06 |
Amunix Operating Inc. |
Xten-folate conjugate compositions and methods of making same
|
CN104136038A
(zh)
|
2012-02-29 |
2014-11-05 |
东丽株式会社 |
体腔积液抑制剂
|
JP6195855B2
(ja)
|
2012-03-03 |
2017-09-13 |
イミュンジーン,インコーポレーテッド |
工学的に作製した抗体−インターフェロン変異体融合分子
|
WO2013137869A1
(en)
|
2012-03-14 |
2013-09-19 |
Boehringer Ingelheim International Gmbh |
Combination therapy for treating hcv infection in an hcv-hiv coinfected patient population
|
JP2015512900A
(ja)
|
2012-03-28 |
2015-04-30 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
特別な患者の遺伝子亜型分集団のhcv感染症を治療するための併用療法
|
CA2868883C
(en)
|
2012-03-30 |
2022-10-04 |
Sorrento Therapeutics Inc. |
Fully human antibodies that bind to vegfr2
|
PT2833905T
(pt)
|
2012-04-04 |
2018-08-06 |
Halozyme Inc |
Terapia de combinação com hialuronidase e um taxano dirigido a tumor
|
AU2013267161A1
(en)
|
2012-05-31 |
2014-11-20 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
JP6438391B2
(ja)
|
2012-06-22 |
2018-12-12 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Ccr2に結合する抗原結合タンパク質
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
JP6433424B2
(ja)
|
2012-07-31 |
2018-12-05 |
バイオアシス テクノロジーズ インコーポレイテッド |
脱リン酸化されたリソソーム蓄積症タンパク質およびその使用方法
|
ES2907763T3
(es)
|
2012-08-31 |
2022-04-26 |
Sutro Biopharma Inc |
Aminoácidos modificados que comprenden un grupo azido
|
WO2014062856A1
(en)
|
2012-10-16 |
2014-04-24 |
Halozyme, Inc. |
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
|
AU2013341711A1
(en)
|
2012-11-12 |
2015-05-21 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
JP2016505528A
(ja)
|
2012-11-16 |
2016-02-25 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
タンパク質の化学修飾のためのピクテ−スペングラーライゲーション
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
US9383357B2
(en)
|
2012-12-07 |
2016-07-05 |
Northwestern University |
Biomarker for replicative senescence
|
JP6426107B2
(ja)
|
2012-12-20 |
2018-11-21 |
アムジエン・インコーポレーテツド |
Apj受容体アゴニストおよびその使用
|
CN103908660B
(zh)
*
|
2013-01-05 |
2015-02-04 |
石药集团百克(山东)生物制药有限公司 |
一种聚乙二醇修饰的rhG-CSF药物组合物及其制备方法
|
EP2951206A2
(de)
|
2013-02-01 |
2015-12-09 |
Bristol-Myers Squibb Company |
Fibronectin-basierte gerüstproteine
|
CN103113466B
(zh)
*
|
2013-03-01 |
2015-06-03 |
中国科学院过程工程研究所 |
聚乙二醇修饰的重组人干扰素β-1b及制备方法
|
UY35397A
(es)
|
2013-03-12 |
2014-10-31 |
Amgen Inc |
INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
|
WO2014160438A1
(en)
|
2013-03-13 |
2014-10-02 |
Bioasis Technologies Inc. |
Fragments of p97 and uses thereof
|
RU2535002C2
(ru)
*
|
2013-04-04 |
2014-12-10 |
Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии" Сибирского отделения Российской академии медицинских наук |
Средство коррекции отдаленных последствий нарушений сперматогенеза, вызванных цитостатическим воздействием
|
EP2986306A4
(de)
|
2013-04-18 |
2016-12-07 |
Armo Biosciences Inc |
Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden
|
US9839579B2
(en)
|
2013-04-24 |
2017-12-12 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9713572B2
(en)
|
2013-04-24 |
2017-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700486B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9849066B2
(en)
|
2013-04-24 |
2017-12-26 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9717648B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707155B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9603775B2
(en)
|
2013-04-24 |
2017-03-28 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707153B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700485B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707154B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9717649B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
CA2914837A1
(en)
|
2013-06-17 |
2014-12-24 |
Armo Biosciences, Inc. |
Method for assessing protein identity and stability
|
TW201534726A
(zh)
|
2013-07-03 |
2015-09-16 |
Halozyme Inc |
熱穩定ph20玻尿酸酶變異體及其用途
|
ES2658039T3
(es)
|
2013-07-10 |
2018-03-08 |
Sutro Biopharma, Inc. |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
US20150093399A1
(en)
|
2013-08-28 |
2015-04-02 |
Bioasis Technologies, Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
EP3038642A4
(de)
|
2013-08-30 |
2017-01-18 |
Armo Biosciences, Inc. |
Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden
|
CN105792839A
(zh)
|
2013-10-02 |
2016-07-20 |
诺华股份有限公司 |
用于治疗的胰岛素样生长因子拟似物
|
WO2015054658A1
(en)
|
2013-10-11 |
2015-04-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
EP3057605A1
(de)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Verfahren zur behandlung von diabetes und verwandten erkrankungen
|
JP6660297B2
(ja)
|
2013-11-11 |
2020-03-11 |
アルモ・バイオサイエンシーズ・インコーポレイテッド |
疾患及び障害を処置するためのインターロイキン−10の使用方法
|
EP3068891A1
(de)
|
2013-11-13 |
2016-09-21 |
Aequus Biopharma Inc. |
Manipulierte glycoproteine und verwendungen davon
|
WO2015081282A1
(en)
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
UY35874A
(es)
|
2013-12-12 |
2015-07-31 |
Novartis Ag |
Un proceso para la preparación de una composición de proteínas pegiladas
|
US10188739B2
(en)
|
2014-02-27 |
2019-01-29 |
Xenetic Biosciences, Inc. |
Compositions and methods for administering insulin or insulin-like protein to the brain
|
WO2015187295A2
(en)
|
2014-06-02 |
2015-12-10 |
Armo Biosciences, Inc. |
Methods of lowering serum cholesterol
|
JP6803236B2
(ja)
|
2014-06-10 |
2020-12-23 |
アムジェン インコーポレイテッド |
アペリンポリペプチド
|
PT3628680T
(pt)
|
2014-06-12 |
2021-10-07 |
Ra Pharmaceuticals Inc |
Modulação da atividade do complemento
|
MX2017002380A
(es)
|
2014-08-22 |
2017-09-15 |
Sorrento Therapeutics Inc |
Proteinas de union de antigeno que se unen a cxcr3.
|
EP3186281B1
(de)
|
2014-08-28 |
2019-04-10 |
Halozyme, Inc. |
Kombinationstherapie mit einer hyaluronanabbauendem enzym und einem immun-checkpoint-hemmer
|
WO2016060996A2
(en)
|
2014-10-14 |
2016-04-21 |
Armo Biosciences, Inc. |
Interleukin-15 compositions and uses thereof
|
NZ730563A
(en)
|
2014-10-14 |
2019-05-31 |
Halozyme Inc |
Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
|
JP6675394B2
(ja)
|
2014-10-22 |
2020-04-01 |
アルモ・バイオサイエンシーズ・インコーポレイテッド |
疾患及び障害の治療のためにインターロイキン−10を使用する方法
|
EA036697B1
(ru)
|
2014-10-24 |
2020-12-09 |
Бристол-Майерс Сквибб Компани |
Модифицированные полипептиды fgf-21 и их применение
|
KR20230079520A
(ko)
|
2014-11-06 |
2023-06-07 |
파마에센시아 코퍼레이션 |
Peg화된 인터페론의 투약 요법
|
US20160151511A1
(en)
|
2014-12-02 |
2016-06-02 |
Antriabio, Inc. |
Proteins and protein conjugates with increased hydrophobicity
|
CN104491843B
(zh)
*
|
2015-01-23 |
2017-09-12 |
石药集团百克(山东)生物制药有限公司 |
一种聚乙二醇修饰的rhG‑CSF活性药物组合物
|
JP6640229B2
(ja)
|
2015-01-28 |
2020-02-05 |
ラ ファーマシューティカルズ インコーポレイテッドRa Pharmaceuticals,Inc. |
補体活性の変調剤
|
WO2016126615A1
(en)
|
2015-02-03 |
2016-08-11 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
WO2016140983A1
(en)
*
|
2015-03-03 |
2016-09-09 |
Avalon Biologics Limited |
Compositions and methods for pegylated il-11
|
EP3265491A1
(de)
|
2015-03-03 |
2018-01-10 |
Xoma (Us) Llc |
Behandlung von postprandialer hyperinsulinämie und hyperglykämie nach bariatrischer chirurgie
|
WO2016161410A2
(en)
|
2015-04-03 |
2016-10-06 |
Xoma Technology Ltd. |
Treatment of cancer using inhibitors of tgf-beta and pd-1
|
WO2016167291A1
(ja)
|
2015-04-13 |
2016-10-20 |
国立研究開発法人産業技術総合研究所 |
環状化サイトカイン及びその製法
|
EP4014985A1
(de)
|
2015-05-01 |
2022-06-22 |
Allysta Pharmaceuticals, Inc. |
Adiponectin-peptidomimetika zur behandlung von augenerkrankungen
|
AU2016268403A1
(en)
|
2015-05-28 |
2017-12-07 |
Armo Biosciences, Inc. |
Pegylated interleukin-10 for use in treating cancer
|
CA2994841A1
(en)
|
2015-08-06 |
2017-02-09 |
Xoma (Us) Llc |
Antibody fragments against the insulin receptor and uses thereof to treat hypoglycemia
|
EP3341012A4
(de)
|
2015-08-25 |
2019-03-20 |
Armo Biosciences, Inc. |
Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden
|
AU2016324119B2
(en)
*
|
2015-09-18 |
2019-11-14 |
Himuka AM Australia Pty Ltd. |
Long-acting adrenomedullin derivative
|
US20180280474A1
(en)
|
2015-10-01 |
2018-10-04 |
Amgen Inc. |
Treatment of bile acid disorders
|
US10935276B2
(en)
|
2015-10-20 |
2021-03-02 |
Steven Michalski |
Air mixing device
|
HUE057083T2
(hu)
|
2015-12-08 |
2022-04-28 |
Biomarin Pharm Inc |
C-típusú nátriuretikus peptid változatainak alkalmazása oszteoartritisz kezelésére
|
MX2018007352A
(es)
|
2015-12-16 |
2019-05-16 |
Ra Pharmaceuticals Inc |
Moduladores de la actividad del complemento.
|
JP6883590B2
(ja)
|
2016-01-29 |
2021-06-09 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Pd−l1に結合する抗原結合性タンパク質
|
EP3490600A1
(de)
|
2016-08-01 |
2019-06-05 |
Xoma (Us) Llc |
Parathormon-rezeptor 1 (pth1r)-antikörper und verwendungen davon
|
CA3038679A1
(en)
|
2016-09-28 |
2018-04-05 |
Xoma (Us) Llc |
Antibodies that bind interleukin-2 and uses thereof
|
MX2019006527A
(es)
|
2016-12-07 |
2019-08-01 |
Ra Pharmaceuticals Inc |
Moduladores de la actividad del complemento.
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
CA3052639A1
(en)
|
2017-02-08 |
2018-08-16 |
Bristol-Myers Squibb Company |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
CN111107870A
(zh)
|
2017-06-22 |
2020-05-05 |
催化剂生物科学公司 |
经修饰的膜型丝氨酸蛋白酶1(mtsp-1)多肽及其使用方法
|
KR102020995B1
(ko)
|
2017-10-30 |
2019-09-16 |
한국코러스 주식회사 |
콜로니자극인자와 폴리올이 접합된 접합물을 고수율로 제조하는 방법
|
CN111094462A
(zh)
|
2017-12-26 |
2020-05-01 |
贝克顿·迪金森公司 |
深紫外线可激发的水溶剂化聚合物染料
|
WO2019130344A1
(en)
|
2017-12-27 |
2019-07-04 |
Council Of Scientific And Industrial Research |
A polypeptide exhibiting granulocyte-colony stimulating factor activity
|
CN112135837A
(zh)
*
|
2018-03-14 |
2020-12-25 |
勇·巴 |
聚乙二醇化抗冻蛋白及其制备和使用方法
|
JP2021519841A
(ja)
|
2018-03-30 |
2021-08-12 |
ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company |
ペンダントクロモフォアを有する水溶性ポリマー色素
|
JP7395504B2
(ja)
|
2018-04-24 |
2023-12-11 |
アムジェン インコーポレイテッド |
注射可能医薬組成物の製造方法
|
US20190351031A1
(en)
|
2018-05-16 |
2019-11-21 |
Halozyme, Inc. |
Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
|
KR102167755B1
(ko)
|
2018-05-23 |
2020-10-19 |
주식회사 큐어바이오 |
단편화된 grs 폴리펩타이드, 이의 변이체 및 이들의 용도
|
EP3813867A1
(de)
|
2018-07-22 |
2021-05-05 |
Bioasis Technologies Inc. |
Behandlung von lymphatischen metastasen
|
FI3849614T3
(fi)
|
2018-09-11 |
2024-02-08 |
Ambrx Inc |
Interleukiini-2-polypeptidikonjugaatteja ja niiden käyttöjä
|
JP2022512746A
(ja)
|
2018-10-19 |
2022-02-07 |
アンブルックス,インコーポレイテッド |
インターロイキン-10ポリペプチド複合体、その二量体、およびそれらの使用
|
US11613744B2
(en)
|
2018-12-28 |
2023-03-28 |
Vertex Pharmaceuticals Incorporated |
Modified urokinase-type plasminogen activator polypeptides and methods of use
|
KR20210110848A
(ko)
|
2018-12-28 |
2021-09-09 |
카탈리스트 바이오사이언시즈, 인코포레이티드 |
변형된 유로키나제 유형 플라스미노겐 활성제 폴리펩타이드 및 사용 방법
|
BR112021015832A2
(pt)
|
2019-02-12 |
2022-01-18 |
Ambrx Inc |
Composições que contêm conjugados de anticorpo-agonista de tlr, métodos e usos dos mesmos
|
US10882954B2
(en)
|
2019-04-11 |
2021-01-05 |
Sunbio Inc. |
Tertiary alkoxy polyethylene glycol and derivatives thereof
|
US20220185969A1
(en)
*
|
2019-04-15 |
2022-06-16 |
Nof Corporation |
Conjugate of bio-related substance and block polymer, and block polymer derivative for obtaining said conjugate
|
WO2020214690A1
(en)
|
2019-04-15 |
2020-10-22 |
Qwixel Therapeutics |
Fusion protein composition(s) comprising targeted masked type i interferons (ifna and ifnb) and an antibody against tumor antigen, for use in the treatment of cancer
|
AU2021233909A1
(en)
|
2020-03-11 |
2022-09-29 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
AU2021240088A1
(en)
|
2020-03-20 |
2022-10-06 |
Amgen Inc. |
Determination of free N-terminus of PEGFilgrastim using an acid protease
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
AU2021327396A1
(en)
|
2020-08-20 |
2023-03-23 |
Ambrx, Inc. |
Antibody-TLR agonist conjugates, methods and uses thereof
|
US11602598B1
(en)
*
|
2020-08-27 |
2023-03-14 |
Fresenius Kabi Deutschland Gmbh |
Prefilled syringe with pegfilgrastim having optimized dose and methods related thereto
|
CN112710826A
(zh)
*
|
2020-11-17 |
2021-04-27 |
北京九强生物技术股份有限公司 |
一种提高试剂稳定性的包被和封闭方法
|
US11952461B2
(en)
|
2021-03-22 |
2024-04-09 |
Sunbio, Inc. |
Siloxy polyethylene glycol and derivatives thereof
|
WO2022212899A1
(en)
|
2021-04-03 |
2022-10-06 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|
CN113214328B
(zh)
*
|
2021-05-08 |
2022-06-28 |
宁波经济技术开发区弘翔生化科技有限公司 |
一种双水相体系以及基于双水相体系的单糖分离方法
|
EP4155349A1
(de)
|
2021-09-24 |
2023-03-29 |
Becton, Dickinson and Company |
Wasserlösliche gelbe grünabsorbierende farbstoffe
|
WO2024007016A2
(en)
|
2022-07-01 |
2024-01-04 |
Beckman Coulter, Inc. |
Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
|
WO2024044327A1
(en)
|
2022-08-26 |
2024-02-29 |
Beckman Coulter, Inc. |
Dhnt monomers and polymer dyes with modified photophysical properties
|