|
KR101607288B1
(ko)
*
|
2005-07-01 |
2016-04-05 |
이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
|
|
TWI729512B
(zh)
|
2008-12-09 |
2021-06-01 |
美商建南德克公司 |
抗pd-l1抗體及其於增進t細胞功能之用途
|
|
US8741591B2
(en)
|
2009-10-09 |
2014-06-03 |
The Research Foundation For The State University Of New York |
pH-insensitive glucose indicator protein
|
|
EP2625292B1
(en)
|
2010-10-07 |
2018-12-05 |
The General Hospital Corporation |
Biomarkers of cancer
|
|
CA2860170C
(en)
|
2010-12-22 |
2022-06-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Superagonists and antagonists of interleukin-2
|
|
EP2537933A1
(en)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
An IL-15 and IL-15Ralpha sushi domain based immunocytokines
|
|
EP3409278B8
(en)
|
2011-07-21 |
2020-11-04 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Heterocyclic protein kinase inhibitors
|
|
KR101981873B1
(ko)
|
2011-11-28 |
2019-05-23 |
메르크 파텐트 게엠베하 |
항-pd-l1 항체 및 그의 용도
|
|
EP2855528B1
(en)
*
|
2012-05-31 |
2019-06-19 |
Genentech, Inc. |
Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
|
|
ES2707323T3
(es)
|
2012-12-07 |
2019-04-03 |
Chemocentryx Inc |
Diazol lactamas
|
|
BR112015013557B1
(pt)
*
|
2012-12-11 |
2021-12-14 |
Albert Einstein College Of Medicine |
Sistema, método, método para determinar o efeito de um resíduo de aminoácido predeterminado de uma primeira proteína sobre a ligação da primeira proteína a uma segunda proteína e polipeptídeo pd-l1 mutante
|
|
WO2014107873A1
(zh)
|
2013-01-11 |
2014-07-17 |
苏州丁孚靶点生物技术有限公司 |
用于肿瘤治疗的试剂、其用途及方法
|
|
KR20220053691A
(ko)
|
2013-03-15 |
2022-04-29 |
제넨테크, 인크. |
Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
|
|
AR095882A1
(es)
|
2013-04-22 |
2015-11-18 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
|
|
KR20160013049A
(ko)
|
2013-06-03 |
2016-02-03 |
노파르티스 아게 |
항-pd-l1 항체 및 mek 억제제 및/또는 braf 억제제의 조합물
|
|
KR20210143932A
(ko)
*
|
2013-09-11 |
2021-11-29 |
메디뮨 리미티드 |
종양 치료용 항-b7-h1 항체
|
|
AR097584A1
(es)
*
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
|
RS63571B9
(sr)
|
2013-09-13 |
2023-02-28 |
Beigene Switzerland Gmbh |
Anti-pd1 antitela i njihova primena kao terapeutska i dijagnostička sredstva
|
|
CA2925421C
(en)
|
2013-09-24 |
2023-08-29 |
Medicenna Therapeutics, Inc. |
Interleukin-2 fusion proteins and uses thereof
|
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
|
LT3049441T
(lt)
|
2013-09-27 |
2020-02-10 |
F. Hoffmann-La Roche Ag |
Anti-pdl1 antikūnų kompozicija
|
|
AU2014339900B2
(en)
*
|
2013-10-25 |
2019-10-24 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
MY189089A
(en)
|
2013-12-17 |
2022-01-25 |
Genentech Inc |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
|
SMT201800643T1
(it)
|
2013-12-24 |
2019-01-11 |
Bristol Myers Squibb Co |
Composti triciclici come agenti anticancro
|
|
CA2935804A1
(en)
*
|
2014-01-14 |
2015-07-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms
|
|
HUE057917T2
(hu)
*
|
2014-01-15 |
2022-06-28 |
Kadmon Corp Llc |
Immunmodulátor szerek
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
CA2974651A1
(en)
|
2014-01-24 |
2015-07-30 |
Children's Hospital Of Eastern Ontario Research Institute Inc. |
Smc combination therapy for the treatment of cancer
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
SI3105246T1
(sl)
|
2014-02-10 |
2021-11-30 |
Merck Patent Gmbh |
Ciljana inhibicija TGF BETA
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
EP3660050A1
(en)
|
2014-03-14 |
2020-06-03 |
Novartis AG |
Antibody molecules to lag-3 and uses thereof
|
|
ES2719136T3
(es)
|
2014-03-24 |
2019-07-08 |
Novartis Ag |
Compuestos orgánicos de monobactam para el tratamiento de infecciones bacterianas
|
|
WO2015164815A1
(en)
|
2014-04-24 |
2015-10-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Superagonists, partial agonists and antagonists of interleukin-2
|
|
CN115590953A
(zh)
|
2014-05-15 |
2023-01-13 |
百时美施贵宝公司(Us) |
使用抗pd-1抗体和另一种抗癌剂的组合治疗肺癌
|
|
EP3149042B1
(en)
|
2014-05-29 |
2019-08-28 |
Spring Bioscience Corporation |
Pd-l1 antibodies and uses thereof
|
|
CN106535884A
(zh)
|
2014-06-06 |
2017-03-22 |
弗雷克萨斯生物科学公司 |
免疫调节剂
|
|
AU2015271709B2
(en)
|
2014-06-06 |
2020-11-26 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
|
|
US10092645B2
(en)
|
2014-06-17 |
2018-10-09 |
Medimmune Limited |
Methods of treatment with antagonists against PD-1 and PD-L1 in combination with radiation therapy
|
|
EP3760208B1
(en)
|
2014-06-25 |
2024-05-29 |
The General Hospital Corporation |
Targeting human satellite ii (hsatii)
|
|
US10544225B2
(en)
|
2014-07-03 |
2020-01-28 |
Beigene, Ltd. |
Anti-PD-L1 antibodies and their use as therapeutics and diagnostics
|
|
CA2954446A1
(en)
|
2014-07-09 |
2016-01-14 |
Shanghai Birdie Biotech, Inc. |
Anti-pd-l1 combinations for treating tumors
|
|
CN106687122B
(zh)
*
|
2014-07-10 |
2020-11-10 |
百奥赛诺公司 |
β-葡聚糖与影响肿瘤微环境的抗癌剂的组合
|
|
RU2715038C2
(ru)
|
2014-07-11 |
2020-02-21 |
Дженентек, Инк. |
Антитела анти-pd-l1 и способы их диагностического применения
|
|
CN106573052B
(zh)
|
2014-07-22 |
2021-04-06 |
中美冠科生物技术(太仓)有限公司 |
抗pd-1抗体
|
|
EP3936145A1
(en)
*
|
2014-07-31 |
2022-01-12 |
The University Of Western Australia |
A method for the identification of immunotherapy-drug combinations using a network approach
|
|
WO2016022630A1
(en)
|
2014-08-05 |
2016-02-11 |
Jiping Zha |
Anti-pd-l1 antibodies
|
|
CN107001316A
(zh)
|
2014-08-06 |
2017-08-01 |
诺华股份有限公司 |
作为抗菌剂的喹诺酮衍生物
|
|
US20170239351A1
(en)
|
2014-08-11 |
2017-08-24 |
Acerta Pharma B.V. |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, a PD-1 Inhibitor, and/or a PD-L1 Inhibitor
|
|
EP3643727A1
(en)
|
2014-08-15 |
2020-04-29 |
Merck Patent GmbH |
Sirp-alpha immunoglobulin fusion proteins
|
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
KR20170060042A
(ko)
|
2014-09-13 |
2017-05-31 |
노파르티스 아게 |
Alk 억제제의 조합 요법
|
|
KR101619862B1
(ko)
*
|
2014-09-30 |
2016-05-12 |
주식회사 녹십자 |
간접효소면역측정법을 이용하는 인간 Fc 포함 단백질의 역가 측정키트 및 이를 이용한 Fc 포함 단백질의 역가 측정방법
|
|
CA2961987A1
(en)
*
|
2014-09-30 |
2016-04-07 |
Intervet International B.V. |
Pd-l1 antibodies binding canine pd-l1
|
|
US20170209574A1
(en)
|
2014-10-03 |
2017-07-27 |
Novartis Ag |
Combination therapies
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
IL251669B2
(en)
|
2014-10-10 |
2023-02-01 |
Idera Pharmaceuticals Inc |
Cancer treatment using a tlr9 agonist with checkpoint inhibitors
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
RU2708459C2
(ru)
|
2014-10-29 |
2019-12-09 |
БайсиклРД Лимитед |
Бициклические пептидные лиганды, специфичные для мт1-ммр
|
|
UY36391A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen
|
|
BR112017008809A2
(pt)
|
2014-11-05 |
2017-12-19 |
Flexus Biosciences Inc |
agentes imunorreguladores
|
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
|
DK3220926T3
(da)
*
|
2014-11-17 |
2025-03-24 |
Adicet Therapeutics Inc |
Konstruerede gamma-delta-t-celler
|
|
AU2015357578B2
(en)
|
2014-12-05 |
2018-11-08 |
Xyphos Biosciences Inc. |
Insertable variable fragments of antibodies and modified a1-a2 domains of NKG2D ligands
|
|
MX2017007636A
(es)
|
2014-12-09 |
2018-03-28 |
Regeneron Pharma |
Animales no humanos que tienen un gen del grupo de diferenciacion 274 humanizado.
|
|
UA121225C2
(uk)
|
2014-12-16 |
2020-04-27 |
Новартіс Аг |
СПОЛУКИ ІЗОКСАЗОЛГІДРОКСАМОВОЇ КИСЛОТИ ЯК ІНГІБІТОРИ LpxC
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
CN105777906B
(zh)
*
|
2014-12-19 |
2019-04-23 |
苏州丁孚靶点生物技术有限公司 |
抗pd-l1全人抗体及其应用
|
|
TW201630907A
(zh)
|
2014-12-22 |
2016-09-01 |
必治妥美雅史谷比公司 |
TGFβR拮抗劑
|
|
JP6180663B2
(ja)
|
2014-12-23 |
2017-08-16 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Tigitに対する抗体
|
|
GB201500319D0
(en)
*
|
2015-01-09 |
2015-02-25 |
Agency Science Tech & Res |
Anti-PD-L1 antibodies
|
|
WO2016123454A1
(en)
|
2015-01-29 |
2016-08-04 |
Board Of Trustees Of Miching State University |
Cryptic polypeptides and uses thereof
|
|
ES2791950T3
(es)
|
2015-02-03 |
2020-11-06 |
Ventana Med Syst Inc |
Ensayo histoquímico para evaluar la expresión del ligando de muerte programada 1 (PD-L1)
|
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
|
WO2016128912A1
(en)
|
2015-02-12 |
2016-08-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor, and/or a pd-l1 inhibitor
|
|
US11318163B2
(en)
|
2015-02-18 |
2022-05-03 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11497767B2
(en)
|
2015-02-18 |
2022-11-15 |
Enlivex Therapeutics R&D Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11596652B2
(en)
|
2015-02-18 |
2023-03-07 |
Enlivex Therapeutics R&D Ltd |
Early apoptotic cells for use in treating sepsis
|
|
US11000548B2
(en)
|
2015-02-18 |
2021-05-11 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11304976B2
(en)
|
2015-02-18 |
2022-04-19 |
Enlivex Therapeutics Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US11512289B2
(en)
|
2015-02-18 |
2022-11-29 |
Enlivex Therapeutics Rdo Ltd |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
RU2714233C2
(ru)
*
|
2015-02-26 |
2020-02-13 |
Мерк Патент Гмбх |
Ингибиторы pd-1 / pd-l1 для лечения рака
|
|
RU2742312C1
(ru)
*
|
2015-02-26 |
2021-02-04 |
Мерк Патент Гмбх |
Ингибиторы pd-1 / pd-l1 для лечения рака
|
|
BR112017017135A2
(pt)
|
2015-03-02 |
2018-04-03 |
Rigel Pharmaceuticals, Inc. |
inibidores de tgf-beta
|
|
US20180044429A1
(en)
|
2015-03-09 |
2018-02-15 |
Celldex Therapeutics, Inc. |
Cd27 agonists
|
|
JO3746B1
(ar)
|
2015-03-10 |
2021-01-31 |
Aduro Biotech Inc |
تركيبات وطرق لتنشيط الإشارات المعتمدة على "منبه أو تحفيز جين انترفيرون"
|
|
WO2016149201A2
(en)
|
2015-03-13 |
2016-09-22 |
Cytomx Therapeutics, Inc. |
Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof
|
|
EP3067062A1
(en)
*
|
2015-03-13 |
2016-09-14 |
Ipsen Pharma S.A.S. |
Combination of tasquinimod or a pharmaceutically acceptable salt thereof and a pd1 and/or pdl1 inhibitor, for use as a medicament
|
|
RS59878B1
(sr)
|
2015-03-23 |
2020-03-31 |
Bayer Pharma AG |
Anti-ceacam6 antitela i njihova primena
|
|
CN114380909A
(zh)
*
|
2015-03-30 |
2022-04-22 |
斯特库比股份有限公司 |
特异性针对糖基化的pd-l1的抗体及其使用方法
|
|
US11933786B2
(en)
|
2015-03-30 |
2024-03-19 |
Stcube, Inc. |
Antibodies specific to glycosylated PD-L1 and methods of use thereof
|
|
AU2016242978A1
(en)
|
2015-04-03 |
2017-11-23 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase for the treatment of cancer
|
|
DK3281641T3
(da)
|
2015-04-07 |
2021-01-18 |
Cytlimic Inc |
Adjuvans til cancervacciner
|
|
TW201642897A
(zh)
|
2015-04-08 |
2016-12-16 |
F 星生物科技有限公司 |
Her2結合劑治療
|
|
PT3283508T
(pt)
|
2015-04-17 |
2021-06-21 |
Alpine Immune Sciences Inc |
Proteínas imuno modulatórias com afinidades afináveis
|
|
KR20250004095A
(ko)
|
2015-04-17 |
2025-01-07 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체 및 또 다른 항체의 조합물을 포함하는 조성물
|
|
US10857181B2
(en)
|
2015-04-21 |
2020-12-08 |
Enlivex Therapeutics Ltd |
Therapeutic pooled blood apoptotic cell preparations and uses thereof
|
|
US20180104331A1
(en)
|
2015-05-11 |
2018-04-19 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
|
EP3294736B1
(en)
|
2015-05-11 |
2020-07-22 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
US10174024B2
(en)
|
2015-05-12 |
2019-01-08 |
Bristol-Myers Squibb Company |
5H-pyrido[3,2-B]indole compounds as anticancer agents
|
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
CA2929848A1
(en)
|
2015-05-14 |
2016-11-14 |
Pfizer Inc. |
Combination therapies comprising a pyrrolidine-2,5-dione ido1 inhibitor and an anti-pd1/anti-pd-l1 antibody
|
|
EP4086264B1
(en)
|
2015-05-18 |
2023-10-25 |
Sumitomo Pharma Oncology, Inc. |
Alvocidib prodrugs having increased bioavailability
|
|
KR20190080992A
(ko)
|
2015-05-21 |
2019-07-08 |
하푼 테라퓨틱스, 인크. |
삼중특이성 결합 단백질 및 사용 방법
|
|
RS62809B1
(sr)
|
2015-05-21 |
2022-02-28 |
Chemocentryx Inc |
Modulatori ccr2
|
|
TWI715587B
(zh)
*
|
2015-05-28 |
2021-01-11 |
美商安可美德藥物股份有限公司 |
Tigit結合劑和彼之用途
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
SI3303394T1
(sl)
|
2015-05-29 |
2020-10-30 |
Agenus Inc. |
Protitelesa proti-CTLA-4 in postopki njihove uporabe
|
|
MX2017015041A
(es)
|
2015-05-29 |
2018-02-26 |
Squibb Bristol Myers Co |
Anticuerpos contra el miembro 4 de la superfamilia del receptor del factor de necrosis tumoral (ox40) y sus usos.
|
|
WO2016196389A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
WO2016196218A1
(en)
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
|
BR112017025742A2
(pt)
*
|
2015-06-09 |
2018-08-07 |
Rexahn Pharmaceuticals, Inc. |
métodos de uso de fluorciclopentanilcitosina
|
|
CN106243225B
(zh)
*
|
2015-06-11 |
2021-01-19 |
智翔(上海)医药科技有限公司 |
新型抗-pd-l1抗体
|
|
US10696745B2
(en)
|
2015-06-11 |
2020-06-30 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Anti-PD-L1 antibodies
|
|
JP2018516969A
(ja)
|
2015-06-12 |
2018-06-28 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Pd−1およびcxcr4シグナル伝達経路の組合せ遮断による癌の処置
|
|
AU2016280003B2
(en)
*
|
2015-06-16 |
2021-09-16 |
Merck Patent Gmbh |
PD-L1 antagonist combination treatments
|
|
CN116327953A
(zh)
|
2015-06-17 |
2023-06-27 |
豪夫迈·罗氏有限公司 |
使用pd-1轴结合拮抗剂和紫杉烷治疗局部晚期或转移性乳腺癌的方法
|
|
IL302486A
(en)
|
2015-06-24 |
2023-06-01 |
Hoffmann La Roche |
Antibodies against the transnephrine receptor with adapted affinity
|
|
MX2017016502A
(es)
|
2015-06-29 |
2018-03-12 |
Univ Rockefeller |
Anticuerpos contra cd40 con actividad agonista mejorada.
|
|
KR20180021882A
(ko)
|
2015-06-29 |
2018-03-05 |
오제 이뮈노테라프틱스 |
짧은 펩타이드 항-암 백신을 이용하여 초기 t 기억 반응을 유도하는 방법
|
|
SMT202100131T1
(it)
|
2015-07-14 |
2021-05-07 |
Bristol Myers Squibb Co |
Metodo di trattamento di un cancro usando un inibitore di checkpoint immunitari; anticorpo che si lega al recettore della morte programmata-1 (pd-1) o al ligando della morte programmata 1 (pd-l1)
|
|
NZ739503A
(en)
|
2015-07-16 |
2023-06-30 |
Bioxcel Therapeutics Inc |
A novel approach for treatment of cancer using immunomodulation
|
|
EP3328861A1
(en)
|
2015-07-28 |
2018-06-06 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
PL3317301T3
(pl)
|
2015-07-29 |
2021-11-15 |
Novartis Ag |
Terapie skojarzone zawierające cząsteczki przeciwciał przeciw lag-3
|
|
CN106397592A
(zh)
*
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
US20180250303A1
(en)
|
2015-08-25 |
2018-09-06 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
|
US9969698B2
(en)
|
2015-09-04 |
2018-05-15 |
Rexahn Pharmaceuticals, Inc. |
Quinoxalinyl-piperazinamide methods of use
|
|
CN114230571B
(zh)
|
2015-09-14 |
2025-07-08 |
无限药品股份有限公司 |
异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
|
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
|
CN106540255A
(zh)
*
|
2015-09-18 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用
|
|
ES2839212T3
(es)
|
2015-09-29 |
2021-07-05 |
Inst Nat Sante Rech Med |
Métodos para determinar el estado metabólico de linfomas B
|
|
JP2018529719A
(ja)
|
2015-09-30 |
2018-10-11 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
Alk陰性がんを処置するためのpd−1系結合アンタゴニストおよびalk阻害剤の組合せ
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
CN114057885A
(zh)
|
2015-10-02 |
2022-02-18 |
豪夫迈·罗氏有限公司 |
双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
|
|
CN106565836B
(zh)
*
|
2015-10-10 |
2020-08-18 |
中国科学院广州生物医药与健康研究院 |
高亲和力的可溶性pdl-1分子
|
|
ES2994611T3
(en)
|
2015-10-19 |
2025-01-27 |
Cg Oncology Inc |
Methods of treating solid or lymphatic tumors by combination therapy
|
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
|
WO2017079202A1
(en)
*
|
2015-11-02 |
2017-05-11 |
Board Of Regents, The University Of Texas System |
Methods of cd40 activation and immune checkpoint blockade
|
|
KR102683841B1
(ko)
*
|
2015-11-17 |
2024-07-10 |
쑤저우 선카디아 바이오파마수티컬즈 컴퍼니 리미티드 |
Pd-l1 항체, 이의 항원-결합 단편 및 이의 약제학적 용도
|
|
PT3377534T
(pt)
|
2015-11-18 |
2025-07-10 |
Bristol Myers Squibb Co |
Tratamento do cancro do pulmão utilizando uma combinação de um anticorpo anti-pd-1 e de um anticorpo anti-ctla-4
|
|
JP6983776B2
(ja)
|
2015-11-19 |
2021-12-17 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
グルココルチコイド誘発腫瘍壊死因子受容体(gitr)に対する抗体およびその使用
|
|
EP3383412A4
(en)
|
2015-12-02 |
2019-06-05 |
Stcube, Inc. |
SPECIFIC ANTIBODIES TO GLYCOSED PD-1 AND METHOD OF USE THEREOF
|
|
CR20180286A
(es)
|
2015-12-03 |
2018-07-16 |
Glaxosmithkline Ip Dev Ltd |
Dinucleotidos de purina cíclicos como moduladores de sting
|
|
ES2823279T3
(es)
*
|
2015-12-07 |
2021-05-06 |
Merck Patent Gmbh |
Formulación farmacéutica acuosa que comprende el anticuerpo anti-PD-1 Avelumab
|
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
|
WO2017106291A1
(en)
|
2015-12-15 |
2017-06-22 |
Bristol-Myers Squibb Company |
Cxcr4 receptor antagonists
|
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Pd−1に対する抗体分子およびその使用
|
|
EP3390454A4
(en)
*
|
2015-12-17 |
2019-08-28 |
University of Maryland, Baltimore County |
RECOMBINANT BISPEZIFIC POLYPEPTIDE FOR THE COORDINATED ACTIVATION OF TUMOR REACTIVE T CELLS AND FOR THE NEUTRALIZATION OF IMMUNOSUPPRESSION
|
|
GB201522309D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
|
GB201522311D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
|
JP2019506844A
(ja)
|
2015-12-18 |
2019-03-14 |
ノバルティス アーゲー |
CD32bを標的とする抗体およびその使用方法
|
|
HRP20231156T1
(hr)
|
2015-12-22 |
2024-01-05 |
Regeneron Pharmaceuticals, Inc. |
Kombinacija anti-pd-1 antitijela i bispecifičnih anti-cd20/anti-cd3 antitijela za liječenje raka
|
|
US11413340B2
(en)
|
2015-12-22 |
2022-08-16 |
Novartis Ag |
Mesothelin chimeric antigen receptor (CAR) and antibody against PD-L1 inhibitor for combined use in anticancer therapy
|
|
PL3394093T3
(pl)
|
2015-12-23 |
2022-05-16 |
Modernatx, Inc. |
Metody stosowania polinukleotydów kodujących ligand ox40
|
|
CN105461808B
(zh)
*
|
2015-12-24 |
2019-03-19 |
长春金赛药业股份有限公司 |
单克隆抗体及其应用
|
|
WO2017118634A1
(en)
|
2016-01-04 |
2017-07-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
|
CN106939047B
(zh)
*
|
2016-01-04 |
2021-08-31 |
江苏怀瑜药业有限公司 |
一种pd-l1抗体及其制备方法
|
|
WO2017122175A1
(en)
|
2016-01-13 |
2017-07-20 |
Acerta Pharma B.V. |
Therapeutic combinations of an antifolate and a btk inhibitor
|
|
EA201891732A1
(ru)
*
|
2016-02-02 |
2019-02-28 |
Кадмон Корпорейшн, Ллк |
Биспецифичные связывающие белки для pd-l1 и kdr
|
|
CA3014885A1
(en)
|
2016-02-18 |
2017-08-24 |
Enlivex Therapeutics Ltd. |
Combination immune therapy and cytokine control therapy for cancer treatment
|
|
US20200270265A1
(en)
|
2016-02-19 |
2020-08-27 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
JP7080819B2
(ja)
|
2016-02-25 |
2022-06-06 |
セル メディカ スイッツァランド アーゲー |
Pd-l1に対する結合メンバー
|
|
EP3309177B1
(en)
*
|
2016-03-04 |
2020-05-13 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Pdl-1 antibody, pharmaceutical composition thereof, and uses thereof
|
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
|
PL3426271T3
(pl)
|
2016-03-10 |
2025-11-24 |
Cg Oncology, Inc. |
Sposoby leczenia guzów litych terapią skojarzoną
|
|
BR112018068461A2
(pt)
|
2016-03-15 |
2019-01-22 |
Mersana Therapeutics Inc |
conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer.
|
|
WO2017159699A1
(en)
|
2016-03-15 |
2017-09-21 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
|
|
CN107216389B
(zh)
|
2016-03-18 |
2022-03-29 |
和迈生物科技有限公司 |
抗pd-l1纳米抗体及其编码序列和用途
|
|
RU2744959C2
(ru)
*
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
WO2017163186A1
(en)
|
2016-03-24 |
2017-09-28 |
Novartis Ag |
Alkynyl nucleoside analogs as inhibitors of human rhinovirus
|
|
JP7572146B2
(ja)
|
2016-03-29 |
2024-10-23 |
エスティーキューブ アンド カンパニー,インコーポレイテッド |
グリコシル化免疫チェックポイントタンパク質に特異的に結合する抗体を選択する方法
|
|
JP7241541B2
(ja)
|
2016-03-29 |
2023-03-17 |
エスティーキューブ,インコーポレイテッド |
グリコシル化pd-l1に特異的な二重機能抗体およびその使用方法
|
|
EP3225253A1
(en)
|
2016-04-01 |
2017-10-04 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
|
|
WO2017176925A1
(en)
|
2016-04-05 |
2017-10-12 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis for predicting prognosis of a patient in need of an anti-cancer treatment
|
|
WO2017176965A1
(en)
|
2016-04-07 |
2017-10-12 |
Chemocentryx, Inc. |
Reducing tumor burden by administering ccr1 antagonists in combination with pd-1 inhibitors or pd-l1 inhibitors
|
|
AU2017249698B2
(en)
|
2016-04-13 |
2023-03-09 |
Vivia Biotech, S.L |
Ex vivo bite-activated T cells
|
|
CN109311989A
(zh)
*
|
2016-04-14 |
2019-02-05 |
创新微技术公司 |
在癌症疗法的治疗决定中的pd-l1表达的应用方法
|
|
ES2990971T3
(es)
|
2016-04-14 |
2024-12-02 |
Ose Immunotherapeutics |
Nuevos anticuerpos anti-SIRPa y sus aplicaciones terapéuticas
|
|
CN109071665B
(zh)
|
2016-04-18 |
2022-11-01 |
塞德斯医疗公司 |
结合人cd40的激动性抗体及其用途
|
|
CN105695406A
(zh)
*
|
2016-04-27 |
2016-06-22 |
天津普瑞赛尔生物科技有限公司 |
制备具有高效肿瘤杀伤性dc-cik免疫细胞的方法及制得的dc-cik免疫细胞
|
|
EP3452450A1
(en)
|
2016-05-04 |
2019-03-13 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US10323004B2
(en)
|
2016-05-04 |
2019-06-18 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
KR20190003686A
(ko)
|
2016-05-04 |
2019-01-09 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
|
EP3452451A4
(en)
|
2016-05-04 |
2019-11-13 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
CN109414421A
(zh)
|
2016-05-04 |
2019-03-01 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
CA3023157A1
(en)
|
2016-05-05 |
2017-11-09 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Enhancer of zeste homolog 2 inhibitors
|
|
SG11201809336QA
(en)
*
|
2016-05-09 |
2018-11-29 |
Igm Biosciences Inc |
Anti-pd-l1 antibodies
|
|
WO2017197347A1
(en)
|
2016-05-12 |
2017-11-16 |
Adicet Bio, Inc. |
METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
DK3458083T5
(da)
|
2016-05-18 |
2024-10-21 |
Modernatx Inc |
Polynukleotider, der koder for interleukin-12 (il12), og anvendelser heraf
|
|
LT3458474T
(lt)
|
2016-05-18 |
2022-10-10 |
Modernatx, Inc. |
Imunitetą moduliuojančius polipeptidus koduojančių mrnr deriniai ir jų naudojimas
|
|
CA3019005A1
(en)
|
2016-05-18 |
2017-11-23 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
EP3458485B1
(en)
|
2016-05-19 |
2021-12-29 |
The General Hospital Corporation |
Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
CA3025024A1
(en)
|
2016-05-20 |
2017-11-23 |
Eli Lilly And Company |
Combination therapy with notch and pd-1 or pd-l1 inhibitors
|
|
WO2017202744A1
(en)
*
|
2016-05-26 |
2017-11-30 |
Merck Patent Gmbh |
Pd-1 / pd-l1 inhibitors for cancer treatment
|
|
TWI895621B
(zh)
|
2016-05-27 |
2025-09-01 |
美商艾吉納斯公司 |
抗-tim-3抗體及其使用方法
|
|
FI3464368T3
(fi)
|
2016-06-02 |
2023-09-12 |
Bristol Myers Squibb Co |
Anti-pd-1-vasta-aineen käyttö yhdistelmänä anti-cd30-vasta-aineen kanssa lymfooman hoitamisessa
|
|
KR20190015377A
(ko)
|
2016-06-02 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
불응성 호지킨 림프종에서의 니볼루맙을 사용한 pd-1 차단
|
|
US20190292260A1
(en)
|
2016-06-03 |
2019-09-26 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treatment of recurrent small cell lung cancer
|
|
WO2017210637A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
|
EP3464369A1
(en)
|
2016-06-03 |
2019-04-10 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treating a tumor
|
|
EP3468960B1
(en)
|
2016-06-08 |
2022-03-23 |
GlaxoSmithKline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
|
US10059769B2
(en)
|
2016-06-13 |
2018-08-28 |
I-Mab |
Anti-PD-L1 antibodies and uses thereof
|
|
CN109414500B
(zh)
*
|
2016-06-13 |
2022-02-25 |
奥美药业有限公司 |
治疗和诊断用pd-l1特异性单克隆抗体
|
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
PT3468957T
(pt)
|
2016-06-14 |
2020-09-24 |
Novartis Ag |
Forma cristalina de (r)-4-(5-(ciclopropiletinil)isoxazol-3-il)-n-hidroxi-2-metil-2-(metilsulfonil)butanamida como um agente antibacteriano
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
JP7461741B2
(ja)
|
2016-06-20 |
2024-04-04 |
カイマブ・リミテッド |
抗pd-l1およびil-2サイトカイン
|
|
SG11201811184UA
(en)
|
2016-06-20 |
2019-01-30 |
F Star Beta Ltd |
Lag -3 binding members
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
WO2018029474A2
(en)
|
2016-08-09 |
2018-02-15 |
Kymab Limited |
Anti-icos antibodies
|
|
EP3475300A2
(en)
|
2016-06-24 |
2019-05-01 |
Xyphos Biosciences Inc. |
Insertable variable fragments of antibodies and modified a1-a2 domains of nkg2d ligands
|
|
UA125216C2
(uk)
|
2016-06-24 |
2022-02-02 |
Інфініті Фармасьютікалз, Інк. |
Комбінована терапія
|
|
CN109641960A
(zh)
*
|
2016-06-29 |
2019-04-16 |
检查点治疗公司 |
Pd-l1特异性抗体及使用其的方法
|
|
WO2018006005A1
(en)
|
2016-06-30 |
2018-01-04 |
Oncorus, Inc. |
Pseudotyped oncolytic viral delivery of therapeutic polypeptides
|
|
WO2018007885A1
(en)
|
2016-07-05 |
2018-01-11 |
Beigene, Ltd. |
COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
EP4512829A3
(en)
|
2016-07-14 |
2025-06-11 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
AU2017300123A1
(en)
|
2016-07-20 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
Isoquinoline derivatives as PERK inhibitors
|
|
EP3487883B1
(en)
|
2016-07-20 |
2023-01-04 |
Stcube, Inc. |
Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated pd-l1
|
|
US20190292179A1
(en)
|
2016-07-21 |
2019-09-26 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
|
WO2018026606A1
(en)
|
2016-08-01 |
2018-02-08 |
Threshold Pharmaceuticals, Inc. |
Administration of hypoxia activated prodrugs in combination with immune modulatory agents for treating cancer
|
|
AU2017305366B2
(en)
*
|
2016-08-04 |
2019-06-20 |
Innovent Biologics (Suzhou) Co., Ltd |
Anti-PD-L1 nanobody and use thereof
|
|
WO2018031507A1
(en)
*
|
2016-08-09 |
2018-02-15 |
Angimmune, Llc |
Treatment of cancer using a combination of immunomodulation and check point inhibitors
|
|
JP7198752B2
(ja)
|
2016-08-09 |
2023-01-04 |
カイマブ・リミテッド |
抗icos抗体
|
|
SG11201901126UA
(en)
*
|
2016-08-12 |
2019-03-28 |
Merck Patent Gmbh |
Combination therapy for cancer
|
|
AU2017313085B2
(en)
|
2016-08-19 |
2024-06-20 |
Beone Medicines I Gmbh |
Use of a combination comprising a Btk inhibitor for treating cancers
|
|
EP3504239B1
(en)
|
2016-08-25 |
2024-05-29 |
F. Hoffmann-La Roche AG |
Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent
|
|
CN109843322A
(zh)
|
2016-08-26 |
2019-06-04 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
CN106248955A
(zh)
*
|
2016-09-03 |
2016-12-21 |
长春工业大学 |
一种检测人源化pd‑l1抗体的试剂盒
|
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
WO2018047109A1
(en)
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Polycyclic pyridone compounds as antivirals
|
|
EP3509634A1
(en)
|
2016-09-09 |
2019-07-17 |
TG Therapeutics Inc. |
Combination of an anti-cd20 antibody, pi3 kinase-delta inhibitor, and anti-pd-1 or anti-pd-l1 antibody for treating hematological cancers
|
|
EP3515936A1
(en)
|
2016-09-23 |
2019-07-31 |
Elstar Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
MX2019003755A
(es)
|
2016-10-06 |
2019-08-12 |
Pfizer |
Regimen de dosificacion de avelumab para el tratamiento de cancer.
|
|
KR102576042B1
(ko)
|
2016-10-11 |
2023-09-07 |
아게누스 인코포레이티드 |
항-lag-3 항체 및 이의 사용 방법
|
|
WO2018070069A1
(ja)
|
2016-10-11 |
2018-04-19 |
サイトリミック株式会社 |
医薬
|
|
BR112018013653B1
(pt)
*
|
2016-10-15 |
2020-12-15 |
Innovent Biologics (Suzhou) Co., Ltd |
Anticorpos anti-pd-1, processo para produção do mesmo e uso dos anticorpos
|
|
WO2018073753A1
(en)
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
|
EP4491237A3
(en)
|
2016-10-28 |
2025-03-26 |
Bristol-Myers Squibb Company |
Methods of treating urothelial carcinoma using an anti-pd-1 antibody
|
|
WO2018080812A1
(en)
*
|
2016-10-30 |
2018-05-03 |
Henlix, Inc. |
Anti-pd-l1 antibodies and variants
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
CA3042679A1
(en)
|
2016-11-03 |
2018-05-11 |
Bristol-Myers Squibb Company |
Activatable anti-ctla-4 antibodies and uses thereof
|
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
JP7750644B2
(ja)
*
|
2016-11-09 |
2025-10-07 |
エンジーン,インコーポレイティド |
プログラム細胞死リガンド1の腸管発現
|
|
WO2018089688A1
(en)
|
2016-11-09 |
2018-05-17 |
Jinjun Shi |
Restoration of tumor suppression using mrna-based delivery system
|
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
|
CN106496327B
(zh)
*
|
2016-11-18 |
2019-01-15 |
昆山百尔泰生物科技有限公司 |
针对pd-l1胞外段的人源抗体或抗体片段和用途、核苷酸序列和载体
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
US20190343803A1
(en)
|
2016-12-01 |
2019-11-14 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
BR112019011350A2
(pt)
|
2016-12-01 |
2019-10-22 |
Glaxosmithkline Ip Dev Ltd |
terapia de combinação
|
|
JP2019536460A
(ja)
|
2016-12-03 |
2019-12-19 |
ジュノー セラピューティクス インコーポレイテッド |
Car−t細胞の調節方法
|
|
JP7106538B2
(ja)
|
2016-12-07 |
2022-07-26 |
アジェナス インコーポレイテッド |
抗体およびその使用方法
|
|
IL266918B2
(en)
|
2016-12-07 |
2024-03-01 |
Agenus Inc |
Anti-ctla-4 antibodies and methods of use thereof
|
|
KR20250040100A
(ko)
|
2016-12-12 |
2025-03-21 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트와 면역 체크 포인트 저해제의 조합
|
|
EP3554535A4
(en)
|
2016-12-14 |
2020-10-21 |
Janssen Biotech, Inc. |
PD-L1 BINDING FIBRONECTIN TYPE III DOMAINS
|
|
KR102568559B1
(ko)
|
2016-12-14 |
2023-08-18 |
얀센 바이오테크 인코포레이티드 |
Cd8a-결합 섬유결합소 iii형 도메인
|
|
US10611823B2
(en)
|
2016-12-14 |
2020-04-07 |
Hanssen Biotech, Inc |
CD137 binding fibronectin type III domains
|
|
WO2018112364A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating melanoma
|
|
WO2018112360A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating cancer
|
|
EP3558360A1
(en)
|
2016-12-22 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Treatment of tumors with an anti-csf-1r antibody in combination with an anti-pd-l1 antibody after failure of anti-pd-l1/pd1 treatment
|
|
US11130931B2
(en)
|
2016-12-22 |
2021-09-28 |
The University Of Hong Kong |
Compositions and methods for clearing tissue
|
|
JP7250677B2
(ja)
|
2016-12-22 |
2023-04-03 |
キュー バイオファーマ, インコーポレイテッド |
T細胞調節多量体ポリペプチド及びその使用方法
|
|
RU2766582C2
(ru)
*
|
2016-12-23 |
2022-03-15 |
Ремд Биотерапьютикс, Инк. |
Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1)
|
|
WO2018132279A1
(en)
|
2017-01-05 |
2018-07-19 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
|
ES2914123T3
(es)
|
2017-01-09 |
2022-06-07 |
Shuttle Pharmaceuticals Inc |
Inhibidores selectivos de la histona desacetilasa para el tratamiento de una enfermedad humana
|
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
US11851471B2
(en)
|
2017-01-09 |
2023-12-26 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
ES2988845T3
(es)
|
2017-01-09 |
2024-11-21 |
Onkosxcel Therapeutics Llc |
Procedimientos predictivos y diagnósticos para cáncer de próstata
|
|
MA47265A
(fr)
|
2017-01-13 |
2019-11-20 |
Agenus Inc |
Récepteurs de lymphocytes t qui se lient à ny-eso-1 et méthodes d'utilisation de ces derniers
|
|
MX389798B
(es)
|
2017-01-20 |
2025-03-20 |
Arcus Biosciences Inc |
Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer.
|
|
MX2019008773A
(es)
|
2017-01-24 |
2019-09-18 |
Pfizer |
Derivados de caliqueamicina y conjugados anticuerpo-farmaco de los mismos.
|
|
HUE058717T2
(hu)
|
2017-01-25 |
2022-09-28 |
Ose Immunotherapeutics |
Eljárás egy stabil emulzió elõállítására peptid szállításához
|
|
CN110461847B
(zh)
|
2017-01-25 |
2022-06-07 |
百济神州有限公司 |
(S)-7-(1-(丁-2-炔酰基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氢吡唑并[1,5-a]嘧啶-3-甲酰胺的结晶形式、其制备及用途
|
|
WO2018140890A1
(en)
*
|
2017-01-29 |
2018-08-02 |
Zequn Tang |
Methods of immune modulation against foreign and/or auto antigens
|
|
WO2018146612A1
(en)
|
2017-02-10 |
2018-08-16 |
Novartis Ag |
1-(4-amino-5-bromo-6-(1 h-pyrazol-1-yl)pyrimidin-2-yl)-1 h-pyrazol-4-ol and use thereof in the treatment of cancer
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
CN108456251A
(zh)
*
|
2017-02-21 |
2018-08-28 |
上海君实生物医药科技股份有限公司 |
抗pd-l1抗体及其应用
|
|
WO2018156888A1
(en)
|
2017-02-24 |
2018-08-30 |
Biothera Pharmaceuticals, Inc. |
Beta glucan immunopharmacodynamics
|
|
BR112019017628A2
(pt)
|
2017-02-24 |
2020-07-07 |
Macrogenics, Inc. |
molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
BR112019018401A2
(pt)
|
2017-03-06 |
2020-04-07 |
Merck Patent Gmbh |
formulação aquosa de anticorpo anti-pd-l1
|
|
EP3372615A1
(en)
|
2017-03-06 |
2018-09-12 |
Merck Patent GmbH |
Composition comprising avelumab
|
|
FI3592769T3
(fi)
|
2017-03-09 |
2024-07-30 |
Genmab As |
Vasta-aineita PD-L1:tä vastaan
|
|
KR102619015B1
(ko)
|
2017-03-15 |
2023-12-28 |
큐 바이오파마, 인크. |
면역 반응을 조절하는 방법
|
|
WO2018170021A1
(en)
*
|
2017-03-16 |
2018-09-20 |
Alpine Immune Sciences, Inc. |
Pd-l1 variant immunomodulatory proteins and uses thereof
|
|
WO2018172508A1
(en)
|
2017-03-24 |
2018-09-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
US20200148785A1
(en)
*
|
2017-03-29 |
2020-05-14 |
Glycotope (GmbH) |
Pd-l1 and ta-muc1 antibodies
|
|
JP7166278B2
(ja)
|
2017-03-30 |
2022-11-07 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
がんの治療のための抗pd-l1抗体およびdna-pkインヒビターの併用
|
|
CA3058175A1
(en)
|
2017-03-31 |
2018-10-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
CA3059366A1
(en)
|
2017-04-13 |
2018-10-18 |
Agenus Inc. |
Anti-cd137 antibodies and methods of use thereof
|
|
RU2665790C1
(ru)
*
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
|
US12460208B2
(en)
|
2017-04-18 |
2025-11-04 |
Parr Biotechnology Co., Ltd. |
Immunomodulatory polynucleotides and uses thereof
|
|
CN110709422B
(zh)
|
2017-04-19 |
2023-12-26 |
马伦戈治疗公司 |
多特异性分子及其用途
|
|
CA3059939A1
(en)
|
2017-04-21 |
2018-10-25 |
Kyn Therapeutics |
Indole ahr inhibitors and uses thereof
|
|
CN110621341A
(zh)
|
2017-04-26 |
2019-12-27 |
百时美施贵宝公司 |
使二硫键还原最小化的抗体生产方法
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
EP4328241A3
(en)
|
2017-04-28 |
2024-06-05 |
Marengo Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
LT3618863T
(lt)
|
2017-05-01 |
2023-10-10 |
Agenus Inc. |
Anti-tigit antikūnai ir jų panaudojimo būdai
|
|
UY37718A
(es)
|
2017-05-05 |
2018-11-30 |
Novartis Ag |
2-quinolinonas triciclicas como agentes antibacteriales
|
|
TW202444417A
(zh)
|
2017-05-09 |
2024-11-16 |
美商提薩羅有限公司 |
治療癌症的組合療法
|
|
CA3061791A1
(en)
|
2017-05-12 |
2019-10-29 |
Jiangsu Hengrui Medicine Co., Ltd. |
Fusion protein containing tgf-.beta. receptor and medicinal uses thereof
|
|
SG10202107880XA
(en)
|
2017-05-12 |
2021-09-29 |
Harpoon Therapeutics Inc |
Mesothelin binding proteins
|
|
WO2018209049A1
(en)
|
2017-05-12 |
2018-11-15 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
|
WO2018213377A1
(en)
|
2017-05-17 |
2018-11-22 |
Arcus Biosciences, Inc. |
Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders
|
|
CA3063723A1
(en)
|
2017-05-18 |
2018-11-22 |
Modernatx, Inc. |
Polynucleotides encoding tethered interleukin-12 (il12) polypeptides and uses thereof
|
|
MA49144A
(fr)
|
2017-05-18 |
2020-03-25 |
Tesaro Inc |
Polythérapies pour le traitement du cancer
|
|
EP3630842A2
(en)
|
2017-05-30 |
2020-04-08 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
|
|
MX2019012076A
(es)
|
2017-05-30 |
2019-12-09 |
Bristol Myers Squibb Co |
Composiciones que comprenden un anticuerpo anti gen-3 de activacion del linfocito (lag-3) o un anticuerpo anti-lag-3 y un anticuerpo anti muerte celular programada 1 (pd-1) o anti ligando 1 de muerte celular programada (pd-l1).
|
|
AU2018277824A1
(en)
|
2017-05-30 |
2019-10-17 |
Bristol-Myers Squibb Company |
Treatment of LAG-3 positive tumors
|
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
|
WO2018223002A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd 123 cd3
|
|
US11566073B2
(en)
|
2017-06-01 |
2023-01-31 |
Bristol-Myers Squibb Company |
Methods of treating a tumor using an anti-PD-1 antibody
|
|
CN110914302A
(zh)
|
2017-06-01 |
2020-03-24 |
赛托姆克斯治疗学股份有限公司 |
可活化抗pdl1抗体及其使用方法
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
BR112019025035A2
(pt)
|
2017-06-01 |
2020-06-30 |
Compugen Ltd. |
método para tratar câncer
|
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
|
CA3066048A1
(en)
|
2017-06-09 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
US11542312B2
(en)
|
2017-06-19 |
2023-01-03 |
Medicenna Therapeutics, Inc. |
IL-2 superagonists in combination with anti-PD-1 antibodies
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
WO2018234879A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
KR20200021087A
(ko)
|
2017-06-22 |
2020-02-27 |
노파르티스 아게 |
Cd73에 대한 항체 분자 및 이의 용도
|
|
EP3645738A4
(en)
*
|
2017-06-25 |
2021-08-18 |
Systimmune, Inc. |
ANTI-PD-L1 ANTIBODIES AND METHODS FOR PREPARATION AND USE
|
|
WO2019001417A1
(en)
|
2017-06-26 |
2019-01-03 |
Beigene, Ltd. |
IMMUNOTHERAPY FOR HEPATOCELLULAR CARCINOMA
|
|
JP2020525483A
(ja)
|
2017-06-27 |
2020-08-27 |
ノバルティス アーゲー |
抗tim−3抗体のための投与レジメンおよびその使用
|
|
AU2018291081B2
(en)
|
2017-06-27 |
2025-02-20 |
Neuracle Science Co., Ltd. |
Use of anti-FAM19A5 antibodies for treating cancers
|
|
IL271601B2
(en)
|
2017-06-30 |
2024-05-01 |
Bristol Myers Squibb Co |
Amorphous and crystalline forms of ido inhibitors
|
|
US20200140383A1
(en)
|
2017-07-03 |
2020-05-07 |
Glaxosmithkline Intellectual Property Development Limited |
2-(4-chlorophenoxy)-n-((1 -(2-(4-chlorophenoxy)ethynazetidin-3-yl)methyl)acetamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
|
WO2019008506A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
N- (3- (2- (4-CHLOROPHENOXY) ACETAMIDO) BICYCLO [1.1.1] PENTAN-1-YL) -2-CYCLOBUTANE-1-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ATF4 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES
|
|
SG11202000248UA
(en)
|
2017-07-14 |
2020-02-27 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
EP3431088A1
(en)
*
|
2017-07-20 |
2019-01-23 |
Paris Sciences et Lettres - Quartier Latin |
Mntbap for use in inducing a transient immune tolerance
|
|
CN111163798A
(zh)
|
2017-07-20 |
2020-05-15 |
诺华股份有限公司 |
用于抗lag-3抗体的给药方案及其用途
|
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
|
WO2019023624A1
(en)
|
2017-07-28 |
2019-01-31 |
Bristol-Myers Squibb Company |
PREDICTIVE PERIPHERAL BLOOD BIOMARKER FOR INHIBITORS OF CONTROL POINTS
|
|
EP4088783A1
(en)
|
2017-08-01 |
2022-11-16 |
Ab Studio Inc. |
Bispecific antibodies and uses thereof
|
|
JP7670481B2
(ja)
|
2017-08-04 |
2025-04-30 |
バイスクルテクス・リミテッド |
Cd137に対して特異的な二環式ペプチドリガンド
|
|
KR102758346B1
(ko)
|
2017-08-04 |
2025-01-24 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
|
JP7423511B2
(ja)
*
|
2017-08-09 |
2024-01-29 |
オリオンズ バイオサイエンス インコーポレイテッド |
Pd-1およびpd-l1結合物質
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
KR20200051646A
(ko)
|
2017-08-17 |
2020-05-13 |
이케나 온콜로지, 인코포레이티드 |
Ahr 억제제 및 이의 용도
|
|
TWI785098B
(zh)
|
2017-08-18 |
2022-12-01 |
開曼群島商科賽睿生命科學公司 |
Tg02之多晶型
|
|
KR20240138135A
(ko)
|
2017-08-25 |
2024-09-20 |
파이브 프라임 테라퓨틱스, 인크. |
B7-h4 항체 및 그의 사용 방법
|
|
KR20200044899A
(ko)
|
2017-08-28 |
2020-04-29 |
브리스톨-마이어스 스큅 컴퍼니 |
암의 치료 및 진단을 위한 tim-3 길항제
|
|
JP7387585B2
(ja)
|
2017-09-04 |
2023-11-28 |
アジェナス インコーポレイテッド |
混合系統白血病(mll)特異的ホスホペプチドに結合するt細胞受容体およびその使用方法
|
|
UY37866A
(es)
|
2017-09-07 |
2019-03-29 |
Glaxosmithkline Ip Dev Ltd |
Nuevos compuestos derivados de benzoimidazol sustituidos que reducen la proteína myc (c-myc) en las células e inhiben la histona acetiltransferasa de p300/cbp.
|
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Mcl-1阻害剤アルボシジブを用いた、bcl-2阻害剤に対して非感受性である癌の治療レジメン
|
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
|
WO2019059411A1
(en)
|
2017-09-20 |
2019-03-28 |
Chugai Seiyaku Kabushiki Kaisha |
DOSAGE FOR POLYTHERAPY USING PD-1 AXIS BINDING ANTAGONISTS AND GPC3 TARGETING AGENT
|
|
CA3076613A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
WO2019060693A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES THEREOF
|
|
US11304952B2
(en)
|
2017-09-25 |
2022-04-19 |
Chemocentryx, Inc. |
Combination therapy using a chemokine receptor 2 (CCR2) antagonist and a PD-1/PD-L1 inhibitor
|
|
AU2018338647B2
(en)
*
|
2017-09-27 |
2025-05-29 |
Angeles Therapeutics, Inc. |
Novel platforms for co-stimulation, novel car designs and other enhancements for adoptive cellular therapy
|
|
EP3697442A4
(en)
|
2017-09-30 |
2021-07-07 |
Tesaro, Inc. |
COMBINATION THERAPIES FOR TREATMENT OF CANCER
|
|
MX2020003799A
(es)
|
2017-10-06 |
2020-11-06 |
Tesaro Inc |
Terapias de combinacion y usos de las mismas.
|
|
WO2019074822A1
(en)
|
2017-10-09 |
2019-04-18 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
US11203592B2
(en)
|
2017-10-09 |
2021-12-21 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US12077588B2
(en)
*
|
2017-10-10 |
2024-09-03 |
Numab Therapeutics AG |
Antibodies targeting PDL1 and methods of use thereof
|
|
CA3075337A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
|
EP3470429A1
(en)
*
|
2017-10-10 |
2019-04-17 |
Numab Innovation AG |
Antibodies targeting pdl1 and methods of use thereof
|
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
|
US12202911B2
(en)
|
2017-10-10 |
2025-01-21 |
Numab Therapeutics AG |
Multispecific antibody comprising CD137 binding domain and PDL1 binding domain
|
|
WO2019075097A1
(en)
|
2017-10-11 |
2019-04-18 |
Board Of Regents, The University Of Texas System |
PD-L1 HUMAN ANTIBODIES AND METHODS OF USE
|
|
JP2020536887A
(ja)
|
2017-10-13 |
2020-12-17 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
Parp阻害剤およびpd−1系結合アンタゴニストの組合せ
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
US11713356B2
(en)
|
2017-10-13 |
2023-08-01 |
Ose Immunotherapeutics |
Modified bifunctional anti-human signal regulatory protein alpha (SIRPa) antibody and method of use thereof for treating cancer
|
|
PL3694529T3
(pl)
|
2017-10-13 |
2024-12-16 |
Harpoon Therapeutics, Inc. |
Trójswoiste białka i sposoby zastosowania
|
|
JP2020536894A
(ja)
|
2017-10-15 |
2020-12-17 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
腫瘍処置法
|
|
EA202090974A1
(ru)
|
2017-10-18 |
2020-08-05 |
Элпайн Иммьюн Сайенсиз, Инк. |
Вариантные иммуномодулирующие белки лиганда icos и сопутствующие композиции и способы
|
|
WO2019077062A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
C-CELLS ACTIVATED BY BIT
|
|
JP7422070B2
(ja)
|
2017-10-19 |
2024-01-25 |
デバイオファーム インターナショナル エス.エー. |
癌の治療のための配合剤
|
|
WO2019083971A1
(en)
|
2017-10-23 |
2019-05-02 |
Children's Medical Center Corporation |
METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY
|
|
EP3700933A1
(en)
|
2017-10-25 |
2020-09-02 |
Novartis AG |
Antibodies targeting cd32b and methods of use thereof
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
JP7167146B2
(ja)
|
2017-11-06 |
2022-11-08 |
ブリストル-マイヤーズ スクイブ カンパニー |
Hpk1阻害剤として有用なイソフラノン化合物
|
|
CN111315397A
(zh)
|
2017-11-06 |
2020-06-19 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
US11529344B2
(en)
|
2017-11-14 |
2022-12-20 |
Pfizer Inc. |
EZH2 inhibitor combination therapies
|
|
WO2019099744A1
(en)
|
2017-11-15 |
2019-05-23 |
Adicet Bio, Inc. |
METHODS FOR SELECTIVE EXPANSION OF δ3 γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
|
|
CN111315749A
(zh)
|
2017-11-17 |
2020-06-19 |
诺华股份有限公司 |
新颖的二氢异噁唑化合物及其在治疗乙型肝炎中的用途
|
|
KR102624844B1
(ko)
|
2017-11-27 |
2024-01-12 |
오제 이뮈노테라프틱스 |
암의 향상된 치료
|
|
WO2019104289A1
(en)
|
2017-11-27 |
2019-05-31 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
US11786529B2
(en)
|
2017-11-29 |
2023-10-17 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors
|
|
SG11202005005YA
(en)
|
2017-11-30 |
2020-06-29 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性分子及びその使用
|
|
TW201938165A
(zh)
|
2017-12-18 |
2019-10-01 |
美商輝瑞股份有限公司 |
治療癌症的方法及組合療法
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
US11629189B2
(en)
|
2017-12-19 |
2023-04-18 |
Kymab Limited |
Bispecific antibody for ICOS and PD-L1
|
|
US11234977B2
(en)
|
2017-12-20 |
2022-02-01 |
Novartis Ag |
Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals
|
|
JP2021506883A
(ja)
|
2017-12-21 |
2021-02-22 |
メルサナ セラピューティクス インコーポレイテッド |
ピロロベンゾジアゼピン抗体結合体
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
JP7284759B2
(ja)
|
2017-12-27 |
2023-05-31 |
ブリストル-マイヤーズ スクイブ カンパニー |
抗cd40抗体およびその使用
|
|
KR102845020B1
(ko)
|
2017-12-28 |
2025-08-12 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-l1에 대한 항체 및 변이체
|
|
US11865081B2
(en)
|
2017-12-29 |
2024-01-09 |
Virogin Biotech Canada Ltd. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
WO2019136179A1
(en)
|
2018-01-03 |
2019-07-11 |
Alpine Immune Sciences, Inc. |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
|
WO2019136112A1
(en)
|
2018-01-05 |
2019-07-11 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US20190269664A1
(en)
|
2018-01-08 |
2019-09-05 |
Chemocentryx, Inc. |
Methods of treating solid tumors with ccr2 antagonists
|
|
EP3737408A1
(en)
|
2018-01-08 |
2020-11-18 |
Novartis AG |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
|
EP3737367B1
(en)
|
2018-01-08 |
2024-10-02 |
ChemoCentryx, Inc. |
Ccr2 antagonists for the treatment of cutaneous t-cell lymphoma
|
|
ES2983284T3
(es)
|
2018-01-09 |
2024-10-22 |
Shuttle Pharmaceuticals Inc |
Inhibidores selectivos de histona deacetilasa para el tratamiento de enfermedades humanas
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
EP3737689A4
(en)
|
2018-01-09 |
2021-12-01 |
Cue Biopharma, Inc. |
MULTIMER POLYPEPTIDES T-LYMPHOCYTE MODULATORS AND THEIR METHODS OF USE
|
|
MX2020007406A
(es)
|
2018-01-10 |
2020-09-14 |
Jiangsu Hengrui Medicine Co |
Anticuerpo pd-l1, fragmento de union al antigeno del mismo y uso farmaceutico del mismo.
|
|
CN120192415A
(zh)
|
2018-01-12 |
2025-06-24 |
百时美施贵宝公司 |
抗tim3抗体及其用途
|
|
US11485743B2
(en)
|
2018-01-12 |
2022-11-01 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
EP3737675A4
(en)
|
2018-01-12 |
2022-01-05 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
CN111770936A
(zh)
|
2018-01-12 |
2020-10-13 |
百时美施贵宝公司 |
抗il-8抗体和抗pd-1抗体联合治疗用于治疗癌症
|
|
EP3740506A1
(en)
|
2018-01-16 |
2020-11-25 |
Bristol-Myers Squibb Company |
Methods of treating cancer with antibodies against tim3
|
|
AU2019210332A1
(en)
|
2018-01-22 |
2020-09-10 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
MX2020007526A
(es)
|
2018-01-22 |
2020-09-09 |
Bristol Myers Squibb Co |
Composiciones y metodos para tratar el cancer.
|
|
IL312674A
(en)
|
2018-01-29 |
2024-07-01 |
Merck Patent Gmbh |
GCN2 inhibitors and uses thereof
|
|
EP3746075B1
(en)
|
2018-01-29 |
2025-09-03 |
Merck Patent GmbH |
Gcn2 inhibitors and uses thereof
|
|
EP3746117A1
(en)
|
2018-01-31 |
2020-12-09 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
|
AU2019215031B2
(en)
|
2018-01-31 |
2025-10-09 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
CN112533613A
(zh)
|
2018-02-06 |
2021-03-19 |
通用医疗公司 |
作为肿瘤免疫应答的生物标志物的重复rna
|
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
US20200399383A1
(en)
|
2018-02-13 |
2020-12-24 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
JP7417527B2
(ja)
|
2018-02-16 |
2024-01-18 |
アーカス バイオサイエンシズ インコーポレイティド |
アゾロピリミジン化合物による投薬
|
|
WO2019162325A1
(en)
|
2018-02-21 |
2019-08-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
|
KR20200123170A
(ko)
|
2018-02-21 |
2020-10-28 |
파이브 프라임 테라퓨틱스, 인크. |
B7-h4 항체 제형
|
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
|
JP2021514953A
(ja)
|
2018-02-23 |
2021-06-17 |
バイスクルテクス・リミテッド |
多量体二環式ペプチドリガンド
|
|
EP3759110A1
(en)
|
2018-02-28 |
2021-01-06 |
Novartis AG |
Indole-2-carbonyl compounds and their use for the treatment of hepatitis b
|
|
MA52416A
(fr)
|
2018-03-02 |
2021-04-21 |
Five Prime Therapeutics Inc |
Anticorps b7-h4 et leurs procédés d'utilisation
|
|
CA3091805A1
(en)
|
2018-03-05 |
2019-09-12 |
Arcus Biosciences, Inc. |
Arginase inhibitors
|
|
JP2021517589A
(ja)
|
2018-03-12 |
2021-07-26 |
アンセルム(アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル) |
癌の治療のための化学免疫療法を増強するためのカロリー制限模倣物の使用
|
|
WO2019175218A1
(en)
|
2018-03-13 |
2019-09-19 |
Ose Immunotherapeutics |
Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
|
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
CA3093499A1
(en)
|
2018-03-14 |
2019-09-19 |
Merck Patent Gmbh |
Compounds and uses thereof to treat tumors in a subject
|
|
KR102495666B1
(ko)
|
2018-03-14 |
2023-02-06 |
서피스 온콜로지, 인크. |
Cd39에 결합하는 항체 및 이의 용도
|
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
WO2019183093A1
(en)
*
|
2018-03-19 |
2019-09-26 |
Abeome Corporation |
High affinity neutralizing monoclonal antibodies to programmed death ligand 1 (pd-l1) and uses thereof
|
|
KR20250154550A
(ko)
|
2018-03-21 |
2025-10-28 |
파이브 프라임 테라퓨틱스, 인크. |
산성 pH에서 VISTA에 결합하는 항체
|
|
KR102879521B1
(ko)
|
2018-03-22 |
2025-11-03 |
서피스 온콜로지, 엘엘씨 |
항-il-27 항체 및 이의 용도
|
|
EP3768726B1
(en)
|
2018-03-23 |
2024-10-30 |
Board of Regents, The University of Texas System |
Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
|
|
WO2019182867A1
(en)
|
2018-03-23 |
2019-09-26 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
|
|
PE20210665A1
(es)
|
2018-03-23 |
2021-03-31 |
Bristol Myers Squibb Co |
Anticuerpos contra mica y/o micb y sus usos
|
|
JP7390301B2
(ja)
|
2018-03-23 |
2023-12-01 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
ヒトpd-l2抗体およびその使用方法
|
|
SG11202009036YA
(en)
|
2018-03-30 |
2020-10-29 |
Merus Nv |
Multivalent antibody
|
|
EP3774911A1
(en)
|
2018-03-30 |
2021-02-17 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3774903A1
(en)
|
2018-04-04 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-cd27 antibodies and uses thereof
|
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
|
CN112218657A
(zh)
|
2018-04-12 |
2021-01-12 |
百时美施贵宝公司 |
Cd73拮抗剂抗体和pd-1/pd-l1轴拮抗剂抗体的抗癌组合疗法
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
WO2019204257A1
(en)
|
2018-04-16 |
2019-10-24 |
Arrys Therapeutics, Inc. |
Ep4 inhibitors and use thereof
|
|
CN112292185B
(zh)
|
2018-04-17 |
2025-07-29 |
塞德斯医疗公司 |
抗cd27和抗pd-l1抗体及双特异性构建体
|
|
JP2021521784A
(ja)
|
2018-04-18 |
2021-08-30 |
ゼンコア インコーポレイテッド |
IL−15/IL−15RaFc融合タンパク質とPD−1抗原結合ドメインを含むPD−1標的化ヘテロダイマー融合タンパク質およびそれらの使用
|
|
IL310398A
(en)
|
2018-04-18 |
2024-03-01 |
Xencor Inc |
Proteins from heterodimeric il-15/il-15rα fc and their uses
|
|
CA3093715A1
(en)
|
2018-04-19 |
2019-10-24 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
BR112020021539A2
(pt)
|
2018-04-25 |
2021-01-19 |
Innate Tumor Immunity, Inc. |
Moduladores de nlrp3
|
|
WO2019210055A2
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
US12037323B2
(en)
|
2018-05-03 |
2024-07-16 |
Bristol-Myers Squibb Company |
Uracil derivatives as Mer-AXL inhibitors
|
|
JP2021522298A
(ja)
|
2018-05-04 |
2021-08-30 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
癌治療のためのPD−1/PD−L1、TGFβおよびDNA−PKの同時阻害
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
US20210205449A1
(en)
|
2018-06-01 |
2021-07-08 |
Novartis Ag |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
WO2019232533A1
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Combination treatments of hsp90 inhibitors for enhancing tumor immunogenicity and methods of use thereof
|
|
JP7398396B2
(ja)
|
2018-06-01 |
2023-12-14 |
ノバルティス アーゲー |
Bcmaに対する結合分子及びその使用
|
|
CN112584861A
(zh)
*
|
2018-06-22 |
2021-03-30 |
维里亚德公司 |
使用组合疗法治疗癌症的方法
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
WO2020006018A1
(en)
|
2018-06-27 |
2020-01-02 |
Bristol-Myers Squibb Company |
Substituted naphthyridinone compounds useful as t cell activators
|
|
PL3814347T3
(pl)
|
2018-06-27 |
2023-07-24 |
Bristol-Myers Squibb Company |
Związki naftyrydynonu użyteczne jako aktywatory komórek t
|
|
US12202879B2
(en)
|
2018-06-29 |
2025-01-21 |
Kookmin University Industry Academy Cooperation Foundation |
PD-L1 variants with enhanced binding affinity to PD-1
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
US11292792B2
(en)
|
2018-07-06 |
2022-04-05 |
Kymera Therapeutics, Inc. |
Tricyclic CRBN ligands and uses thereof
|
|
US20210253528A1
(en)
|
2018-07-09 |
2021-08-19 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
MY201995A
(en)
|
2018-07-09 |
2024-03-28 |
Five Prime Therapeutics Inc |
Antibodies binding to ilt4
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
PL3820573T3
(pl)
|
2018-07-10 |
2024-02-19 |
Novartis Ag |
Pochodne 3-(5-hydroksy-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu i ich zastosowanie w leczeniu chorób zależnych od palca cynkowego z rodziny ikaros 2 (ikzf2)
|
|
CN112703198B
(zh)
|
2018-07-11 |
2025-05-30 |
布里格姆妇女医院 |
用于跨血脑屏障递送试剂的方法和组合物
|
|
CA3106108A1
(en)
*
|
2018-07-11 |
2020-01-16 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered fc-antigen binding domain constructs targeted to pd-l1
|
|
JP7700036B2
(ja)
|
2018-07-11 |
2025-06-30 |
ファイヴ プライム セラピューティクス インク |
酸性pHでVISTAと結合する抗体
|
|
MX2021000399A
(es)
|
2018-07-12 |
2021-05-27 |
F Star Therapeutics Ltd |
Moleculas de anticuerpo que se unen a cd137 y ox40.
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
AU2019301204B2
(en)
|
2018-07-12 |
2025-10-23 |
Invox Pharma Limited |
Antibody molecules that bind PD-L1 and CD137
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
|
CN113015523B
(zh)
|
2018-07-18 |
2024-07-16 |
艾库斯生物科学有限公司 |
偶氮嘧啶化合物的固体形式
|
|
MX2021000745A
(es)
|
2018-07-20 |
2021-03-26 |
Surface Oncology Inc |
Composiciones anti-cd112r y metodos.
|
|
US12145927B2
(en)
|
2018-07-23 |
2024-11-19 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2020023355A1
(en)
|
2018-07-23 |
2020-01-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
CN112041348B
(zh)
|
2018-07-25 |
2023-09-22 |
天境生物科技(上海)有限公司 |
抗cd73抗pd-l1双特异性抗体
|
|
AU2019309849A1
(en)
|
2018-07-26 |
2021-03-18 |
Bristol-Myers Squibb Company |
LAG-3 combination therapy for the treatment of cancer
|
|
KR20210038580A
(ko)
|
2018-07-31 |
2021-04-07 |
도꾜 다이가꾸 |
새로운 결합 특이성을 항체에 부여하는 초범용법
|
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
WO2020037092A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
MX2021001581A
(es)
|
2018-08-16 |
2021-04-19 |
Innate Tumor Immunity Inc |
Compuestos de 4-amino-1h-imidazo[4,5-c]quinolina sustituidos y metodos mejorados para su preparacion.
|
|
WO2020037091A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
PE20211412A1
(es)
|
2018-08-20 |
2021-08-02 |
Pfizer |
Anticuerpos anti-gdf15, composiciones y metodos de uso
|
|
KR20210046725A
(ko)
|
2018-08-20 |
2021-04-28 |
1글로브 바이오메디칼 씨오., 엘티디. |
신규 암 면역요법 항체 조성물
|
|
CN112955221A
(zh)
|
2018-08-27 |
2021-06-11 |
皮里斯制药有限公司 |
包含cd137/her2双特异性试剂和pd-1轴抑制剂的组合疗法及其用途
|
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
US11331269B2
(en)
|
2018-09-06 |
2022-05-17 |
Massachusetts Institute Of Technology |
Methods and compositions targeting lung microbiota and its responding immune pathways for lung cancer treatment
|
|
CN112955155A
(zh)
*
|
2018-09-07 |
2021-06-11 |
总医院公司 |
用于免疫检查点抑制的组合物和方法
|
|
EP3846793B1
(en)
|
2018-09-07 |
2024-01-24 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
EP3849979A1
(en)
|
2018-09-12 |
2021-07-21 |
Novartis AG |
Antiviral pyridopyrazinedione compounds
|
|
CN109053891B
(zh)
*
|
2018-09-17 |
2021-12-21 |
苏州泓迅生物科技股份有限公司 |
一种抗pd-l1抗体及其制备方法和应用
|
|
WO2020058372A1
(en)
|
2018-09-19 |
2020-03-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
MX2021002887A
(es)
|
2018-09-20 |
2021-06-04 |
Iovance Biotherapeutics Inc |
Expansion de linfocitos infiltrantes de tumores (tils) a partir de muestras de tumor crioconservadas.
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
CN113286817B
(zh)
|
2018-09-25 |
2025-01-28 |
哈普恩治疗公司 |
Dll3结合蛋白及使用方法
|
|
AU2019346012A1
(en)
|
2018-09-26 |
2021-04-15 |
Merck Patent Gmbh |
Combination of a PD-1 antagonist, an ATR inhibitor and a platinating agent for the treatment of cancer
|
|
EP3856350A1
(en)
|
2018-09-27 |
2021-08-04 |
Marengo Therapeutics, Inc. |
Csf1r/ccr2 multispecific antibodies
|
|
US20220040183A1
(en)
|
2018-10-01 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
SG11202103192RA
(en)
|
2018-10-03 |
2021-04-29 |
Xencor Inc |
Il-12 heterodimeric fc-fusion proteins
|
|
JP2022512642A
(ja)
|
2018-10-09 |
2022-02-07 |
ブリストル-マイヤーズ スクイブ カンパニー |
がんを治療するための抗MerTK抗体
|
|
JP2022504839A
(ja)
|
2018-10-10 |
2022-01-13 |
ティロス・セラピューティクス・インコーポレイテッド |
抗lap抗体変異体及びその使用
|
|
CA3116188A1
(en)
|
2018-10-12 |
2020-04-16 |
Xencor, Inc. |
Pd-1 targeted il-15/il-15ralpha fc fusion proteins and uses in combination therapies thereof
|
|
US20210348238A1
(en)
|
2018-10-16 |
2021-11-11 |
Novartis Ag |
Tumor mutation burden alone or in combination with immune markers as biomarkers for predicting response to targeted therapy
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
ES2986921T3
(es)
|
2018-10-19 |
2024-11-13 |
Bristol Myers Squibb Co |
Terapia combinada para el melanoma
|
|
CN113226369A
(zh)
|
2018-10-22 |
2021-08-06 |
葛兰素史克知识产权开发有限公司 |
给药
|
|
JP2022505647A
(ja)
|
2018-10-23 |
2022-01-14 |
ブリストル-マイヤーズ スクイブ カンパニー |
腫瘍の処置方法
|
|
EP3873534A1
(en)
|
2018-10-29 |
2021-09-08 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
|
US20230053449A1
(en)
|
2018-10-31 |
2023-02-23 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
JP2022505923A
(ja)
|
2018-11-01 |
2022-01-14 |
メルク パテント ゲーエムベーハー |
抗tim-3抗体を投与する方法
|
|
EP3873611A1
(en)
|
2018-11-01 |
2021-09-08 |
Merck Patent GmbH |
Anti-tim-3 antibodies
|
|
US20210386826A1
(en)
|
2018-11-05 |
2021-12-16 |
Pfizer Inc. |
Combination for Treating Cancer
|
|
WO2020095184A1
(en)
|
2018-11-05 |
2020-05-14 |
Pfizer Inc. |
Combinations for treating cancer
|
|
CN120983617A
(zh)
|
2018-11-06 |
2025-11-21 |
健玛保 |
抗体配制剂
|
|
WO2020097409A2
(en)
|
2018-11-08 |
2020-05-14 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
JP7436477B2
(ja)
|
2018-11-09 |
2024-02-21 |
ジエンス ヘンルイ メデイシンカンパニー リミテッド |
TGF-β受容体融合タンパク質医薬組成物およびその使用
|
|
HUE067601T2
(hu)
|
2018-11-14 |
2024-10-28 |
Regeneron Pharma |
PD-1 inhibitorok intraléziós beadása a bõrrák kezelésére
|
|
CN112996814B
(zh)
|
2018-11-14 |
2025-01-03 |
拜耳公司 |
用于治疗癌症的抗ceacam6和抗pd-1或抗pd-l1抗体的药物组合
|
|
CA3119341A1
(en)
|
2018-11-16 |
2020-05-22 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
|
|
US11274150B2
(en)
|
2018-11-16 |
2022-03-15 |
Bristol-Myers Squibb Company |
Anti-human natural killer cell inhibitory receptor group 2A protein (NKG2A) antibodies
|
|
CA3120196A1
(en)
|
2018-11-16 |
2020-05-22 |
Arcus Biosciences, Inc. |
Inhibitors of arg1 and/or arg2
|
|
EP3883964A1
(en)
|
2018-11-20 |
2021-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
|
CA3119467A1
(en)
|
2018-11-20 |
2020-05-28 |
Cornell University |
Macrocyclic complexes of radionuclides and their use in radiotherapy of cancer
|
|
CN113453678A
(zh)
|
2018-11-26 |
2021-09-28 |
德彪药业国际股份公司 |
Hiv感染的联合治疗
|
|
WO2020109355A1
(en)
|
2018-11-28 |
2020-06-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and kit for assaying lytic potential of immune effector cells
|
|
CA3121140A1
(en)
|
2018-11-30 |
2020-06-04 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds useful in hiv therapy
|
|
JP7623943B2
(ja)
|
2018-11-30 |
2025-01-29 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
|
CA3119807A1
(en)
|
2018-12-04 |
2020-06-11 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
CN113167802B
(zh)
|
2018-12-04 |
2025-02-07 |
百时美施贵宝公司 |
通过多同位素体反应监测使用样品内校准曲线的分析方法
|
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
|
EP3894440A4
(en)
|
2018-12-13 |
2022-09-07 |
Surface Oncology, Inc. |
ANTI-IL-27 ANTIBODIES AND THEIR USES
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
BR112021007968A2
(pt)
|
2018-12-19 |
2021-09-08 |
Bayer Aktiengesellschaft |
Combinação farmacêutica de anticorpos anti-ceacam6 e tim3
|
|
WO2020127411A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
CN113271945A
(zh)
|
2018-12-20 |
2021-08-17 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合
|
|
US11618776B2
(en)
|
2018-12-20 |
2023-04-04 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15RA and NKG2D antigen binding domains
|
|
US20220025036A1
(en)
|
2018-12-21 |
2022-01-27 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
IL282838B2
(en)
|
2018-12-21 |
2025-05-01 |
Valerio Therapeutics |
Conjugated nucleic acid molecules and their uses
|
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
CN113227137A
(zh)
|
2018-12-21 |
2021-08-06 |
诺华股份有限公司 |
IL-1β抗体在骨髓增生异常综合征的治疗或预防中的用途
|
|
EP3897849A1
(en)
|
2018-12-21 |
2021-10-27 |
BicycleTx Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
KR20210108422A
(ko)
|
2018-12-21 |
2021-09-02 |
노파르티스 아게 |
IL-1β 결합 항체의 용도
|
|
US20220370606A1
(en)
|
2018-12-21 |
2022-11-24 |
Pfizer Inc. |
Combination Treatments Of Cancer Comprising A TLR Agonist
|
|
BR112021012630A2
(pt)
|
2018-12-28 |
2022-12-13 |
Transgene Sa |
Poxvírus modificado, método para produzir o poxvírus modificado e composição
|
|
US12187706B2
(en)
|
2019-01-14 |
2025-01-07 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
KR102815870B1
(ko)
|
2019-01-14 |
2025-05-30 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
암의 치료에 사용하기 위한 헤테로시클릭 nlrp3 조정제
|
|
EP3911641A1
(en)
|
2019-01-14 |
2021-11-24 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
WO2020150116A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
SG11202107606VA
(en)
|
2019-01-15 |
2021-08-30 |
Inst Nat Sante Rech Med |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
EA202191992A1
(ru)
|
2019-01-18 |
2021-12-17 |
Дрейсен Фармасьютикалз, Инк. |
Комбинированная терапия пролекарством don и ингибитором иммунных контрольных точек
|
|
EP3917579A4
(en)
|
2019-01-28 |
2023-03-29 |
AB Therapeutics, Inc. |
SPECIFIC ANTIBODIES AND USES THEREOF
|
|
US20220107323A1
(en)
|
2019-01-30 |
2022-04-07 |
Inserm(Institut National De La Santé Et De La Recherche Médicale) |
Methods and compositions for identifying whether a subject suffering from a cancer will achieve a response with an immune-checkpoint inhibitor
|
|
CN113365659B
(zh)
*
|
2019-01-31 |
2023-08-18 |
正大天晴药业集团股份有限公司 |
抗pd-l1抗体治疗头颈癌的用途
|
|
WO2020161083A1
(en)
|
2019-02-04 |
2020-08-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
|
CA3127502A1
(en)
|
2019-02-12 |
2020-08-20 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
EP3924520A1
(en)
|
2019-02-13 |
2021-12-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
|
JP7483732B2
(ja)
|
2019-02-15 |
2024-05-15 |
ノバルティス アーゲー |
3-(1-オキソ-5-(ピペリジン-4-イル)イソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
EP3927347B1
(en)
*
|
2019-02-18 |
2023-12-27 |
Medivir Aktiebolag |
Drug combination for use in a method of treating liver cancer
|
|
CA3130578A1
(en)
|
2019-02-19 |
2020-08-27 |
Myst Therapeutics, Llc |
Methods for producing autologous t cells useful to treat cancers and compositions thereof
|
|
AU2020224681A1
(en)
|
2019-02-21 |
2021-09-16 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to NKp30 and uses thereof
|
|
JP2022521305A
(ja)
*
|
2019-02-21 |
2022-04-06 |
ユーカー(ベンジン) バイオファーマ カンパニー,リミテッド |
抗pd-l1抗体及びその使用
|
|
GB2599228B
(en)
|
2019-02-21 |
2024-02-07 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
EP3930848A1
(en)
|
2019-02-28 |
2022-01-05 |
Regeneron Pharmaceuticals, Inc. |
Administration of pd-1 inhibitors for treating skin cancer
|
|
EP3935085A1
(en)
|
2019-03-06 |
2022-01-12 |
Regeneron Pharmaceuticals, Inc. |
Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer
|
|
AU2020239048B2
(en)
|
2019-03-12 |
2025-10-16 |
Arcus Biosciences, Inc. |
Treatment of oncogene-driven cancers
|
|
WO2020187998A1
(en)
|
2019-03-19 |
2020-09-24 |
Fundació Privada Institut D'investigació Oncològica De Vall Hebron |
Combination therapy with omomyc and an antibody binding pd-1 or ctla-4 for the treatment of cancer
|
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
|
CA3133460A1
(en)
|
2019-03-22 |
2020-10-01 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprising pkm2 modulators and methods of treatment using the same
|
|
AU2020248002A1
(en)
|
2019-03-26 |
2021-10-21 |
The Regents Of The University Of Michigan |
Small molecule degraders of STAT3
|
|
JP2022526960A
(ja)
|
2019-03-28 |
2022-05-27 |
ブリストル-マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
EP3946625A1
(en)
|
2019-03-28 |
2022-02-09 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
JP7743309B2
(ja)
|
2019-03-29 |
2025-09-24 |
アーカス バイオサイエンシズ インコーポレイティド |
同定されたアデノシンフィンガープリントを利用したがんの処置
|
|
EP3947403A1
(en)
|
2019-03-29 |
2022-02-09 |
The Regents Of The University Of Michigan |
Stat3 protein degraders
|
|
BR112021019328A2
(pt)
|
2019-03-29 |
2021-11-30 |
Myst Therapeutics Llc |
Métodos ex vivo para produzir um produto terapêutico de célula t e composições e métodos relacionados
|
|
WO2020206169A1
(en)
|
2019-04-02 |
2020-10-08 |
Kupper Thomas S |
Methods for identifying progression of a primary melanoma
|
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
EP3946462A1
(en)
|
2019-04-02 |
2022-02-09 |
BicycleTX Limited |
Bicycle toxin conjugates and uses thereof
|
|
MX2021012216A
(es)
|
2019-04-05 |
2022-01-24 |
Kymera Therapeutics Inc |
Degradadores de transductores de señal y activadores de transcripción (stat) y usos de los mismos.
|
|
EP3952850A1
(en)
|
2019-04-09 |
2022-02-16 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
WO2020208612A1
(en)
|
2019-04-12 |
2020-10-15 |
Vascular Biogenics Ltd. |
Methods of anti-tumor therapy
|
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
AU2020261961B2
(en)
*
|
2019-04-26 |
2022-07-07 |
I-Mab Biopharma Co., Ltd. |
Human PD-L1 antibodies
|
|
US20220220565A1
(en)
|
2019-04-30 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2020227431A1
(en)
*
|
2019-05-06 |
2020-11-12 |
Brown University |
Bispecific antibodies against chi3l1 and pd1 with enhanced t cell-mediated cytotoxic effects on tumor cells
|
|
WO2020239558A1
(en)
|
2019-05-24 |
2020-12-03 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
|
CN114174538A
(zh)
|
2019-05-30 |
2022-03-11 |
百时美施贵宝公司 |
适合于免疫肿瘤学疗法的多肿瘤基因特征
|
|
EP3977132A1
(en)
|
2019-05-30 |
2022-04-06 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
CA3141826A1
(en)
|
2019-05-31 |
2020-12-03 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
AU2020290119B2
(en)
*
|
2019-06-10 |
2024-07-18 |
Shandong Boan Biotechnology Co., Ltd. |
Bifunctional fusion protein against PDL1 and TGFβ and use thereof
|
|
US20220220204A1
(en)
*
|
2019-06-12 |
2022-07-14 |
Nanjing GenScript Biotech Co., Ltd. |
Anti-pd-l1/anti-lag-3 multiple antigen binding proteins and methods of use thereof
|
|
KR102517872B1
(ko)
*
|
2019-06-12 |
2023-04-05 |
(주)아큐레시스바이오 |
암의 예방 또는 치료용 조성물
|
|
EP3983084A1
(en)
|
2019-06-12 |
2022-04-20 |
Vanderbilt University |
Amino acid transport inhibitors and the uses thereof
|
|
AU2020291936A1
(en)
|
2019-06-12 |
2022-02-03 |
Vanderbilt University |
Dibenzylamines as amino acid transport inhibitors
|
|
BR112021026334A2
(pt)
|
2019-06-27 |
2022-05-10 |
Medstar Health |
Macrófagos ativados por hdac6, composições, e usos dos mesmos
|
|
WO2021003417A1
(en)
|
2019-07-03 |
2021-01-07 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Tyrosine kinase non-receptor 1 (tnk1) inhibitors and uses thereof
|
|
GB201910138D0
(en)
*
|
2019-07-15 |
2019-08-28 |
Capella Bioscience Ltd |
Anti-pd-l1 antibodies
|
|
JP7738909B2
(ja)
|
2019-07-16 |
2025-09-16 |
ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン |
Eed阻害剤としてのイミダゾピリミジンおよびその使用
|
|
CN114269780B
(zh)
|
2019-07-19 |
2024-01-19 |
北京先通生物医药技术有限公司 |
一种新型抗pd-l1抗体及其用途
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
CN114641337A
(zh)
|
2019-08-27 |
2022-06-17 |
密歇根大学董事会 |
Cereblon e3连接酶抑制剂
|
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
|
WO2021042019A1
(en)
|
2019-08-30 |
2021-03-04 |
Agenus Inc. |
Anti-cd96 antibodies and methods of use thereof
|
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
US12215105B2
(en)
|
2019-09-13 |
2025-02-04 |
Nimbus Saturn, Inc. |
HPK1 antagonists and uses thereof
|
|
US11655303B2
(en)
|
2019-09-16 |
2023-05-23 |
Surface Oncology, Inc. |
Anti-CD39 antibody compositions and methods
|
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
|
US11918649B2
(en)
|
2019-09-18 |
2024-03-05 |
Molecular Templates, Inc. |
PD-L1-binding molecules comprising Shiga toxin a subunit scaffolds
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
KR20220081977A
(ko)
|
2019-09-18 |
2022-06-16 |
몰레큘러 템플레이츠, 인코퍼레이션. |
시가 독소 a 서브유닛 스캐폴드를 포함하는 pd-l1 결합분자(pd-l1 binding molecules comprising shiga toxin a subunit scaffolds)
|
|
US20220380368A1
(en)
|
2019-09-19 |
2022-12-01 |
The Regents Of The University Of Michigan |
Spirocyclic androgen receptor protein degraders
|
|
MX2022003204A
(es)
|
2019-09-19 |
2022-04-18 |
Bristol Myers Squibb Co |
Anticuerpos de union al supresor de activacion de linfocitos t que contiene inmunoglobulina con dominio v (vista) a ph acido.
|
|
JP7732977B2
(ja)
|
2019-09-20 |
2025-09-02 |
トランスジーン |
Hpvポリペプチドおよびil-2をコードするポックスウイルスと抗pd-l1抗体の組合せ
|
|
BR112022004316A2
(pt)
|
2019-09-22 |
2022-06-21 |
Bristol Myers Squibb Co |
Caracterização espacial quantitativa para terapia de antagonista lag-3
|
|
BR112022004302A2
(pt)
|
2019-09-25 |
2022-06-21 |
Surface Oncology Inc |
Anticorpos anti-il-27 e usos dos mesmos
|
|
AU2020353079A1
(en)
|
2019-09-25 |
2022-04-14 |
Bristol-Myers Squibb Company |
Composite biomarker for cancer therapy
|
|
TW202535873A
(zh)
|
2019-09-26 |
2025-09-16 |
瑞士商諾華公司 |
抗病毒吡唑并吡啶酮化合物
|
|
AU2020355614B2
(en)
|
2019-09-27 |
2024-12-05 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding proteins
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
US20220354811A1
(en)
|
2019-10-03 |
2022-11-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
|
CN115916233A
(zh)
|
2019-10-03 |
2023-04-04 |
Xencor股份有限公司 |
靶向IL-12异源二聚体Fc融合蛋白
|
|
US20220363776A1
(en)
|
2019-10-04 |
2022-11-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
US12491255B2
(en)
|
2019-10-14 |
2025-12-09 |
Aro Biotherapeutics Company |
EPCAM binding fibronectin type III domains
|
|
WO2021076574A2
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
WO2021076546A1
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Cd71 binding fibronectin type iii domains
|
|
US20240301497A1
(en)
|
2019-10-17 |
2024-09-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
|
MX2022004766A
(es)
|
2019-10-21 |
2022-05-16 |
Novartis Ag |
Terapias combinadas con venetoclax e inhibidores de tim-3.
|
|
TW202128191A
(zh)
|
2019-10-21 |
2021-08-01 |
瑞士商諾華公司 |
Tim-3抑制劑及其用途
|
|
JP7707161B2
(ja)
|
2019-10-23 |
2025-07-14 |
チェックメイト ファーマシューティカルズ, インコーポレイテッド |
合成rig-i様受容体アゴニスト
|
|
US20240190961A1
(en)
|
2019-10-25 |
2024-06-13 |
Daiichi Sankyo Company, Limited |
Combination of anti-garp antibody and immunomodulator
|
|
US20240122938A1
(en)
|
2019-10-29 |
2024-04-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating uveal melanoma
|
|
KR20220092918A
(ko)
|
2019-11-04 |
2022-07-04 |
알렉터 엘엘씨 |
Siglec-9 ecd 융합 분자 및 이의 사용 방법
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
KR20220093349A
(ko)
|
2019-11-08 |
2022-07-05 |
브리스톨-마이어스 스큅 컴퍼니 |
흑색종에 대한 lag-3 길항제 요법
|
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
|
JP7629459B2
(ja)
|
2019-11-19 |
2025-02-13 |
ブリストル-マイヤーズ スクイブ カンパニー |
Heliosタンパク質の阻害剤として有用な化合物
|
|
JP2023502264A
(ja)
|
2019-11-22 |
2023-01-23 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
固体用量医薬組成物
|
|
AU2020394424A1
(en)
|
2019-11-26 |
2022-06-16 |
Ikena Oncology, Inc. |
Polymorphic carbazole derivatives and uses thereof
|
|
CA3159071A1
(en)
|
2019-11-26 |
2021-06-03 |
Tamar I. ROSENBAUM |
Salts/cocrystals of (r)-n-(4-chlorophenyl)-2-((1s,4s)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
|
|
EP4066852A4
(en)
|
2019-11-27 |
2024-05-22 |
NEC Corporation |
PHARMACEUTICAL COMPOSITION
|
|
CA3162703A1
(en)
|
2019-11-27 |
2021-06-03 |
Myst Therapeutics, Llc |
Method of producing tumor-reactive t cell composition using modulatory agents
|
|
US11591332B2
(en)
|
2019-12-17 |
2023-02-28 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
KR20220145325A
(ko)
|
2019-12-17 |
2022-10-28 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak 분해제 및 이의 용도
|
|
EP4076508A1
(en)
|
2019-12-19 |
2022-10-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
|
MX2022006932A
(es)
|
2019-12-19 |
2022-07-11 |
Bristol Myers Squibb Co |
Combinaciones de inhibidores de diacilglicerol cinasas (dgk) y antagonistas de puntos de control.
|
|
TW202135859A
(zh)
|
2019-12-20 |
2021-10-01 |
瑞士商諾華公司 |
組合療法
|
|
KR20220120624A
(ko)
|
2019-12-23 |
2022-08-30 |
브리스톨-마이어스 스큅 컴퍼니 |
T 세포 활성화제로서 유용한 치환된 피페라진 유도체
|
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
|
WO2021133920A1
(en)
|
2019-12-23 |
2021-07-01 |
Kymera Therapeutics, Inc. |
Smarca degraders and uses thereof
|
|
WO2021133752A1
(en)
|
2019-12-23 |
2021-07-01 |
Bristol-Myers Squibb Company |
Substituted heteroaryl compounds useful as t cell activators
|
|
CN115103841B
(zh)
|
2019-12-23 |
2024-12-27 |
百时美施贵宝公司 |
可用作t细胞激活剂的经取代的喹啉酮基哌嗪化合物
|
|
BR112022012179A2
(pt)
|
2019-12-23 |
2022-09-06 |
Bristol Myers Squibb Co |
Compostos de quinazolina substituída úteis como ativadores de célula t
|
|
EP4084821A4
(en)
|
2020-01-03 |
2024-04-24 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
JP2023509708A
(ja)
|
2020-01-03 |
2023-03-09 |
マレンゴ・セラピューティクス,インコーポレーテッド |
抗tcr抗体分子およびその使用
|
|
CA3166898A1
(en)
|
2020-01-06 |
2021-07-15 |
Hifibio (Hk) Limited |
Anti-tnfr2 antibody and uses thereof
|
|
CN115210261B
(zh)
|
2020-01-07 |
2025-07-18 |
高诚生物医药公司 |
抗半乳糖凝集素-9抗体及其用途
|
|
CN115279400A
(zh)
|
2020-01-10 |
2022-11-01 |
布里格姆妇女医院 |
用于跨血脑屏障递送免疫治疗剂以治疗脑癌的方法和组合物
|
|
US12492200B2
(en)
|
2020-01-10 |
2025-12-09 |
Birstol Myers-Squibb Company |
NLRP3 modulators
|
|
JP2023510918A
(ja)
|
2020-01-15 |
2023-03-15 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤
|
|
EP4090770A1
(en)
|
2020-01-17 |
2022-11-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
BR112022012310A2
(pt)
|
2020-01-17 |
2022-09-06 |
Novartis Ag |
Combinação compreendendo um inibidor de tim-3 e um agente hipometilante para uso no tratamento de síndrome mielodisplásica ou leucemia mielomonocítica crônica
|
|
AU2021213317A1
(en)
|
2020-01-28 |
2022-06-30 |
Centre National De La Recherche Scientifique |
Antisense oligonucleotide targeting LINC00518 for treating melanoma
|
|
CN116407626A
(zh)
|
2020-01-29 |
2023-07-11 |
美勒斯公司 |
用于调节免疫细胞衔接效应的手段和方法
|
|
IL295093A
(en)
|
2020-01-30 |
2022-09-01 |
Ona Therapeutics S L |
Combination therapy for treatment of cancer and cancer metastasis
|
|
US20230072528A1
(en)
|
2020-02-05 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
|
EP4100426A1
(en)
|
2020-02-06 |
2022-12-14 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
IL295188A
(en)
|
2020-02-18 |
2022-09-01 |
Alector Llc |
Pilra antibodies and methods of use thereof
|
|
AU2021226903A1
(en)
|
2020-02-27 |
2022-10-20 |
Turnstone Biologics Corp. |
Methods for ex vivo enrichment and expansion of tumor reactive T cells and related compositions thereof
|
|
US20230113705A1
(en)
|
2020-02-28 |
2023-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
|
CN116568341A
(zh)
|
2020-02-28 |
2023-08-08 |
百时美施贵宝公司 |
基于纤连蛋白的放射性标记的支架和抗体及其治疗诊断用途
|
|
WO2021171264A1
(en)
|
2020-02-28 |
2021-09-02 |
Novartis Ag |
Dosing of a bispecific antibody that binds cd123 and cd3
|
|
US11753403B2
(en)
|
2020-03-03 |
2023-09-12 |
PIC Therapeutics, Inc. |
EIF4E inhibitors and uses thereof
|
|
AU2021232158A1
(en)
|
2020-03-06 |
2022-09-29 |
Ona Therapeutics, S.L. |
Anti-CD36 antibodies and their use to treat cancer
|
|
WO2021178807A1
(en)
|
2020-03-06 |
2021-09-10 |
Celgene Quanticel Research, Inc. |
Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
|
|
EP3878446A1
(en)
|
2020-03-09 |
2021-09-15 |
Universite De Geneve |
Hsd11b1 inhibitors for use in immunotherapy and uses thereof
|
|
JP2023516459A
(ja)
|
2020-03-09 |
2023-04-19 |
ブリストル-マイヤーズ スクイブ カンパニー |
増強されたアゴニスト活性を有するcd40に対する抗体
|
|
WO2021188948A1
(en)
|
2020-03-19 |
2021-09-23 |
Kymera Therapeutics, Inc. |
Mdm2 degraders and uses thereof
|
|
WO2021188769A1
(en)
|
2020-03-19 |
2021-09-23 |
Arcus Biosciences, Inc. |
Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha
|
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
|
US20230119066A1
(en)
|
2020-03-23 |
2023-04-20 |
Bristol-Myers Squibb Company |
Anti-ccr8 antibodies for treating cancer
|
|
US20230159573A1
(en)
|
2020-03-26 |
2023-05-25 |
The Regents Of The University Of Michigan |
Small molecule stat protein degraders
|
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
|
WO2021209358A1
(en)
|
2020-04-14 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer based upon an icos antibody and a pd-l1 antibody tgf-beta-receptor fusion protein
|
|
US12159700B2
(en)
|
2020-04-22 |
2024-12-03 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
WO2021219807A1
(en)
*
|
2020-04-30 |
2021-11-04 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Pd-l1 variants with improved affinity towards pd-1
|
|
WO2021224215A1
(en)
|
2020-05-05 |
2021-11-11 |
F. Hoffmann-La Roche Ag |
Predicting response to pd-1 axis inhibitors
|
|
CA3169949A1
(en)
|
2020-05-12 |
2021-11-18 |
Cue Biopharma, Inc. |
Multimeric t-cell modulatory polypeptides and methods of use thereof
|
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
EP4157464A1
(en)
|
2020-05-26 |
2023-04-05 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cervical cancer by administering the pd-1 inhibitor antibody cemiplimab
|
|
WO2021239838A2
(en)
|
2020-05-26 |
2021-12-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
WO2021243207A1
(en)
|
2020-05-28 |
2021-12-02 |
Modernatx, Inc. |
Use of mrnas encoding ox40l, il-23 and il-36gamma for treating cancer
|
|
AR122493A1
(es)
|
2020-06-02 |
2022-09-14 |
Arcus Biosciences Inc |
Anticuerpos anti-tigit
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
WO2021247897A1
(en)
|
2020-06-03 |
2021-12-09 |
Kymera Therapeutics, Inc. |
Deuterated irak degraders and uses thereof
|
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
|
KR20230027056A
(ko)
|
2020-06-23 |
2023-02-27 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법
|
|
WO2022003554A1
(en)
|
2020-07-01 |
2022-01-06 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
|
KR20230035576A
(ko)
|
2020-07-07 |
2023-03-14 |
비온테크 에스이 |
Hpv 양성 암 치료용 rna
|
|
US20230257365A1
(en)
|
2020-07-10 |
2023-08-17 |
The Regents Of The University Of Michigan |
Small molecule androgen receptor protein degraders
|
|
WO2022011205A1
(en)
|
2020-07-10 |
2022-01-13 |
The Regents Of The University Of Michigan |
Androgen receptor protein degraders
|
|
WO2022023379A1
(en)
|
2020-07-28 |
2022-02-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for preventing and treating a cancer
|
|
JP2023536462A
(ja)
|
2020-07-30 |
2023-08-25 |
カイメラ セラピューティクス, インコーポレイテッド |
変異体リンパ腫を処置する方法
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
IL300537A
(en)
|
2020-08-10 |
2023-04-01 |
Gv20 Therapeutics Llc |
Compositions and methods for treating autoimmune diseases and cancer by targeting IGSF8
|
|
KR20230074721A
(ko)
|
2020-08-17 |
2023-05-31 |
바이사이클티엑스 리미티드 |
Nectin-4에 특이적인 이환 콘쥬게이트 및 이의 용도
|
|
EP4204592A1
(en)
|
2020-08-26 |
2023-07-05 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer by administering a pd-1 inhibitor
|
|
KR20230074487A
(ko)
|
2020-08-26 |
2023-05-30 |
마렝고 테라퓨틱스, 인크. |
Trbc1 또는 trbc2를 검출하는 방법
|
|
MX2023002332A
(es)
|
2020-08-28 |
2023-03-21 |
Bristol Myers Squibb Co |
Terapia con antagonistas del gen 3 de activacion de linfocitos (lag-3) para carcinoma hepatocelular.
|
|
CA3190660A1
(en)
|
2020-08-31 |
2022-03-03 |
George C. Lee |
Cell localization signature and immunotherapy
|
|
CN111808196B
(zh)
*
|
2020-08-31 |
2020-12-29 |
北京百奥赛图基因生物技术有限公司 |
抗pd-1抗体及其用途
|
|
US11932692B2
(en)
|
2020-09-03 |
2024-03-19 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer pain by administering a PD-1 inhibitor
|
|
JP2023541366A
(ja)
|
2020-09-09 |
2023-10-02 |
キュー バイオファーマ, インコーポレイテッド |
1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節多量体ポリペプチド及びその使用方法
|
|
CR20230155A
(es)
|
2020-09-14 |
2023-06-27 |
Boehringer Ingelheim Int |
Vacuna heteróloga de estímulo primario
|
|
CN117157314A
(zh)
*
|
2020-09-16 |
2023-12-01 |
苏州逻晟生物医药有限公司 |
Pd-l1抗体、融合蛋白及其用途
|
|
CN111920948B
(zh)
*
|
2020-09-25 |
2021-02-02 |
安可瑞(山西)生物细胞有限公司 |
包含免疫细胞的药物组合物用于治疗癌症
|
|
WO2022072820A1
(en)
|
2020-10-02 |
2022-04-07 |
Dracen Pharmaceuticals, Inc. |
Lyophilized composition comprising (s)-isopropyl 2-((s)-2- acetamido-3-(1h-indol-3-yl)propanamido)-6-diazo-5- oxohexanoate for subcutaneous administration and the use thereof
|
|
JP2023544410A
(ja)
|
2020-10-05 |
2023-10-23 |
ブリストル-マイヤーズ スクイブ カンパニー |
タンパク質を濃縮するための方法
|
|
US20230364127A1
(en)
|
2020-10-06 |
2023-11-16 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
CA3196496A1
(en)
|
2020-10-23 |
2022-04-28 |
Laurence David TOMS |
Lag-3 antagonist therapy for lung cancer
|
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
|
KR20230098279A
(ko)
|
2020-10-28 |
2023-07-03 |
이케나 온콜로지, 인코포레이티드 |
Pdx 억제제 또는 독소루비신과 ahr 억제제의 조합
|
|
EP3992208A1
(en)
*
|
2020-11-03 |
2022-05-04 |
Randox Laboratories Ltd |
Anti-pd-l1 vhh antibodies
|
|
IL302569A
(en)
|
2020-11-06 |
2023-07-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
MX2023005570A
(es)
|
2020-11-12 |
2023-05-29 |
Inst Nat Sante Rech Med |
Anticuerpos conjugados o fusionados al dominio de union del receptor de la proteina de la espicula de sars-cov-2 y usos de los mismos con fines de vacunacion.
|
|
US20230416838A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
EP4244391A1
(en)
|
2020-11-16 |
2023-09-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
EP4255895A1
(en)
|
2020-12-02 |
2023-10-11 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
|
EP4262858A1
(en)
|
2020-12-16 |
2023-10-25 |
Molecular Templates, Inc. |
Clinical methods for use of a pd-l1-binding molecule comprising a shiga toxin effector
|
|
JP2024501207A
(ja)
|
2020-12-16 |
2024-01-11 |
ゴッサマー バイオ サービシズ、インコーポレイテッド |
T細胞活性化剤として有用な化合物
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
SMT202500208T1
(it)
|
2020-12-28 |
2025-07-22 |
Bristol Myers Squibb Co |
Composizioni anticorpali e metodi per il loro uso
|
|
CA3196999A1
(en)
|
2020-12-28 |
2022-07-07 |
Masano HUANG |
Methods of treating tumors
|
|
AR124547A1
(es)
|
2020-12-30 |
2023-04-05 |
Kymera Therapeutics Inc |
Degradadores de irak y sus usos
|
|
WO2022148736A1
(en)
|
2021-01-05 |
2022-07-14 |
Transgene |
Vectorization of muc1 t cell engager
|
|
US20250186539A2
(en)
|
2021-01-11 |
2025-06-12 |
Bicycletx Limited |
Methods for treating cancer
|
|
WO2022156727A1
(zh)
|
2021-01-21 |
2022-07-28 |
浙江养生堂天然药物研究所有限公司 |
治疗肿瘤的组合物及方法
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
BR112023015590A2
(pt)
|
2021-02-02 |
2023-10-17 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 e usos dos mesmos
|
|
US12378229B2
(en)
|
2021-02-02 |
2025-08-05 |
Liminal Biosciences Limited |
GPR84 antagonists and uses thereof
|
|
WO2022171121A1
(zh)
|
2021-02-10 |
2022-08-18 |
同润生物医药(上海)有限公司 |
治疗肿瘤的方法和组合
|
|
US20240368150A1
(en)
|
2021-02-12 |
2024-11-07 |
Hoffmann-La Roche Inc. |
Bicyclic tetrahydroazepine derivatives for the treatment of cancer
|
|
WO2022174253A1
(en)
|
2021-02-12 |
2022-08-18 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
US11773103B2
(en)
|
2021-02-15 |
2023-10-03 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and uses thereof
|
|
MX2023009527A
(es)
|
2021-02-15 |
2023-08-24 |
Kymera Therapeutics Inc |
Degradadores de la cinasa 4 asociada al receptor de interleucina 1 (irak4) y usos de los mismos.
|
|
EP4301733A1
(en)
|
2021-03-02 |
2024-01-10 |
GlaxoSmithKline Intellectual Property Development Limited |
Substituted pyridines as dnmt1 inhibitors
|
|
US20240190874A1
(en)
|
2021-03-03 |
2024-06-13 |
The Regents Of The University Of Michigan |
Small molecule degraders of androgen receptor
|
|
US20240166647A1
(en)
|
2021-03-03 |
2024-05-23 |
The Regents Of The University Of Michigan |
Cereblon Ligands
|
|
CN117677634A
(zh)
|
2021-03-05 |
2024-03-08 |
利达提斯有限公司 |
三聚体多肽及其在治疗癌症中的用途
|
|
EP4301756A4
(en)
|
2021-03-05 |
2025-02-26 |
Nimbus Saturn, Inc. |
HPK1 ANTAGONISTS AND THEIR USES
|
|
JP2024510176A
(ja)
|
2021-03-08 |
2024-03-06 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤
|
|
US11918582B2
(en)
|
2021-03-15 |
2024-03-05 |
Rapt Therapeutics, Inc. |
Pyrazole pyrimidine compounds and uses thereof
|
|
EP4308118A1
(en)
|
2021-03-17 |
2024-01-24 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for treating melanoma
|
|
WO2022195551A1
(en)
|
2021-03-18 |
2022-09-22 |
Novartis Ag |
Biomarkers for cancer and methods of use thereof
|
|
IL305776A
(en)
|
2021-03-23 |
2023-11-01 |
Regeneron Pharma |
Methods of treating cancer in patients with suppression or failure of the immune system through the administration of a PD-1 inhibitor
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
JP2024514245A
(ja)
|
2021-03-29 |
2024-03-29 |
ジュノー セラピューティクス インコーポレイテッド |
チェックポイント阻害剤療法とcar t細胞療法との組合せを用いた投薬および処置のための方法
|
|
US12071442B2
(en)
|
2021-03-29 |
2024-08-27 |
Nimbus Saturn, Inc. |
Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists
|
|
JP2024511831A
(ja)
|
2021-03-31 |
2024-03-15 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
抗原結合タンパク質およびそれらの組み合わせ
|
|
EP4314068A1
(en)
|
2021-04-02 |
2024-02-07 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
EP4320125A1
(en)
|
2021-04-05 |
2024-02-14 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds for the treatment of cancer
|
|
IL307343A
(en)
|
2021-04-06 |
2023-11-01 |
Bristol Myers Squibb Co |
Pyridinyl substituted oxisoisoindoline compounds
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
WO2022216993A2
(en)
|
2021-04-08 |
2022-10-13 |
Marengo Therapeutics, Inc. |
Multifuntional molecules binding to tcr and uses thereof
|
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
WO2022214653A1
(en)
|
2021-04-09 |
2022-10-13 |
Ose Immunotherapeutics |
New scaffold for bifunctional molecules with improved properties
|
|
BR112023020781A2
(pt)
|
2021-04-09 |
2023-12-19 |
Nimbus Clio Inc |
Moduladores de cbl-b e usos dos mesmos
|
|
CA3213079A1
(en)
|
2021-04-13 |
2022-10-20 |
Kristin Lynne ANDREWS |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
EP4322938A1
(en)
|
2021-04-14 |
2024-02-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
New method to improve nk cells cytotoxicity
|
|
US12239710B2
(en)
|
2021-04-14 |
2025-03-04 |
Aro Biotherapeutics Company |
FN3 domain-siRNA conjugates and uses thereof
|
|
CA3214552A1
(en)
|
2021-04-14 |
2022-10-20 |
Russell C. Addis |
Cd71 binding fibronectin type iii domains
|
|
EP4323066A1
(en)
|
2021-04-16 |
2024-02-21 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
|
KR20240005809A
(ko)
|
2021-05-07 |
2024-01-12 |
서피스 온콜로지, 엘엘씨 |
항-il-27 항체 및 이의 용도
|
|
AR125798A1
(es)
|
2021-05-07 |
2023-08-16 |
Kymera Therapeutics Inc |
Degradadores cdk2 y usos de los mismos
|
|
WO2022243378A1
(en)
|
2021-05-18 |
2022-11-24 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
JP2024518641A
(ja)
|
2021-05-21 |
2024-05-01 |
天津立博美華基因科技有限責任公司 |
医薬物組合せ及びその使用
|
|
WO2022246179A1
(en)
|
2021-05-21 |
2022-11-24 |
Arcus Biosciences, Inc. |
Axl inhibitor compounds
|
|
CN117295741A
(zh)
|
2021-05-21 |
2023-12-26 |
艾库斯生物科学有限公司 |
Axl化合物
|
|
EP4346887A1
(en)
|
2021-05-25 |
2024-04-10 |
Edelweiss Immune Inc |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
EP4349863A2
(en)
|
2021-05-26 |
2024-04-10 |
Centro de Inmunologia Molecular |
Use of therapeutic compositions for the treatment of patients with tumours of epithelial origin
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
US11572412B2
(en)
|
2021-06-04 |
2023-02-07 |
Boehringer Ingelheim International Gmbh |
Anti-SIRP-alpha antibodies
|
|
WO2023280790A1
(en)
|
2021-07-05 |
2023-01-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
AU2022312698A1
(en)
|
2021-07-13 |
2024-01-25 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
JP2024527608A
(ja)
|
2021-07-14 |
2024-07-25 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤としての複素環化合物
|
|
TW202321238A
(zh)
|
2021-07-15 |
2023-06-01 |
美商纜圖藥品公司 |
Map4k1抑制劑
|
|
MX2024000406A
(es)
|
2021-07-19 |
2024-04-18 |
Regeneron Pharma |
Combinacion de inhibidores de puntos de control y un virus oncolitico para el tratamiento del cancer.
|
|
EP4377344A1
(en)
|
2021-07-30 |
2024-06-05 |
Ona Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
CA3229560A1
(en)
|
2021-08-25 |
2023-03-02 |
Christopher L. Vandeusen |
Eif4e inhibitors and uses thereof
|
|
JP2024532276A
(ja)
|
2021-08-25 |
2024-09-05 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
|
IL310773A
(en)
|
2021-09-02 |
2024-04-01 |
Deutsches Krebsforschungszentrum Stiftung Des ?Ffentlichen Rechts |
Anti-CECAM6 antibodies with reduced side effects
|
|
WO2023039089A1
(en)
|
2021-09-08 |
2023-03-16 |
Twentyeight-Seven, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
JP2024540106A
(ja)
|
2021-10-28 |
2024-10-31 |
ライエル・イミュノファーマ・インコーポレイテッド |
免疫細胞を培養するための方法
|
|
CN118176214A
(zh)
|
2021-10-29 |
2024-06-11 |
百时美施贵宝公司 |
血液癌症的lag-3拮抗剂疗法
|
|
EP4422635A4
(en)
|
2021-10-29 |
2025-11-26 |
Kymera Therapeutics Inc |
IRAQ4 DEGRADATION AGENTS AND THEIR SYNTHESIS
|
|
WO2023079430A1
(en)
|
2021-11-02 |
2023-05-11 |
Pfizer Inc. |
Methods of treating mitochondrial myopathies using anti-gdf15 antibodies
|
|
US20240426823A1
(en)
|
2021-11-03 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
KR20240103030A
(ko)
|
2021-11-17 |
2024-07-03 |
인스티튜트 내셔날 드 라 싼테 에 드 라 리셰르셰 메디칼르 |
범용 사르베코바이러스 백신
|
|
US20240294926A1
(en)
|
2021-12-16 |
2024-09-05 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
EP4452257A1
(en)
|
2021-12-21 |
2024-10-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
JP2025501238A
(ja)
|
2021-12-30 |
2025-01-17 |
ネオイミューンテック, インコーポレイテッド |
Il-7タンパク質とvegfアンタゴニストの併用による腫瘍の治療方法
|
|
MX2024008831A
(es)
|
2022-01-26 |
2024-07-25 |
Bristol Myers Squibb Co |
Terapia combinada para carcinoma hepatocelular.
|
|
CA3243560A1
(en)
|
2022-01-31 |
2023-08-03 |
Kymera Therapeutics, Inc. |
Iraqi Degradation Agents and Their Uses
|
|
JP2025503312A
(ja)
|
2022-02-01 |
2025-01-30 |
アルビナス・オペレーションズ・インコーポレイテッド |
Dgk標的化化合物およびその使用
|
|
TWI864587B
(zh)
|
2022-02-14 |
2024-12-01 |
美商基利科學股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
WO2023159102A1
(en)
|
2022-02-17 |
2023-08-24 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
|
WO2023164638A1
(en)
|
2022-02-25 |
2023-08-31 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
IL315262A
(en)
|
2022-03-03 |
2024-10-01 |
Pfizer |
Multiple specific antibodies related to IL-4, IL-13 and/or TSLP and their uses
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
KR20230130911A
(ko)
|
2022-03-04 |
2023-09-12 |
주식회사 온코인사이트 |
암 예방 또는 치료를 위한 병용 투여용 약학 조성물
|
|
CN119156403A
(zh)
|
2022-03-08 |
2024-12-17 |
阿伦蒂斯治疗股份公司 |
抗紧密连接蛋白-1抗体增加t细胞可用性的用途
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
US20250177352A1
(en)
|
2022-03-14 |
2025-06-05 |
Laekna Limited |
Combination treatment for cancer
|
|
MX2024011278A
(es)
|
2022-03-15 |
2024-09-25 |
Compugen Ltd |
Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.
|
|
US20250195645A1
(en)
|
2022-03-16 |
2025-06-19 |
Daiichi Sankyo Company, Limited |
Combination of multispecific molecule and immune checkpoint inhibitor
|
|
KR20240159621A
(ko)
|
2022-03-18 |
2024-11-05 |
브리스톨-마이어스 스큅 컴퍼니 |
폴리펩티드를 단리하는 방법
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2023196988A1
(en)
|
2022-04-07 |
2023-10-12 |
Modernatx, Inc. |
Methods of use of mrnas encoding il-12
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
CN119731651A
(zh)
|
2022-04-08 |
2025-03-28 |
百时美施贵宝公司 |
三级淋巴结构的机器学习标识、分类和量化
|
|
EP4507704A1
(en)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
WO2023213763A1
(en)
*
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
WO2023213764A1
(en)
*
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
US20250340641A1
(en)
|
2022-05-18 |
2025-11-06 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
KR20250012631A
(ko)
|
2022-05-24 |
2025-01-24 |
다이이찌 산쿄 가부시키가이샤 |
항-cdh6 항체-약물 접합체의 투약
|
|
IL316768A
(en)
|
2022-05-25 |
2025-01-01 |
Ikena Oncology Inc |
MEK inhibitors and their uses
|
|
WO2023235847A1
(en)
|
2022-06-02 |
2023-12-07 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
EP4561599A1
(en)
|
2022-07-27 |
2025-06-04 |
Astrazeneca AB |
Combinations of recombinant virus expressing interleukin-12 with pd-1/pd-l1 inhibitors
|
|
MA71616A
(fr)
|
2022-07-28 |
2025-05-30 |
Daiichi Sankyo Company, Limited |
Association d'un conjugué anticorps-médicament et d'un inhibiteur de point de contrôle bispécifique
|
|
IL318577A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND THEIR USES
|
|
JP2025527248A
(ja)
|
2022-08-02 |
2025-08-20 |
リミナル・バイオサイエンシーズ・リミテッド |
置換ピリドンgpr84アンタゴニスト及びその使用
|
|
IL318575A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
HETEROARYL CARBOXAMIDE AND GPR84-RELATED ANTAGONISTS AND USES THEREOF
|
|
CN119654312A
(zh)
|
2022-08-08 |
2025-03-18 |
百时美施贵宝公司 |
用作t细胞活化剂的取代的四唑基化合物
|
|
WO2024036101A1
(en)
|
2022-08-09 |
2024-02-15 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
|
CR20250042A
(es)
|
2022-08-11 |
2025-03-25 |
Hoffmann La Roche |
Derivados de tetrahidrotiazepina bicíclicos
|
|
CN119677732A
(zh)
|
2022-08-11 |
2025-03-21 |
豪夫迈·罗氏有限公司 |
双环四氢氮杂䓬衍生物
|
|
EP4568746A1
(en)
|
2022-08-11 |
2025-06-18 |
F. Hoffmann-La Roche AG |
Bicyclic tetrahydrothiazepine derivatives
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
EP4583999A1
(en)
|
2022-09-09 |
2025-07-16 |
Bristol-Myers Squibb Company |
Methods of separating chelator
|
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
|
WO2024069009A1
(en)
|
2022-09-30 |
2024-04-04 |
Alentis Therapeutics Ag |
Treatment of drug-resistant hepatocellular carcinoma
|
|
KR20250089513A
(ko)
|
2022-10-19 |
2025-06-18 |
아스텔라스세이야쿠 가부시키가이샤 |
암 치료에 있어서의 pd-1 시그널 저해제와의 조합에 의한 항cldn4-항cd137 이중특이성 항체의 사용
|
|
EP4605000A1
(en)
|
2022-10-21 |
2025-08-27 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
|
AU2023374571A1
(en)
|
2022-11-01 |
2025-04-03 |
Heidelberg Pharma Research Gmbh |
Anti-gucy2c antibody and uses thereof
|
|
TW202421194A
(zh)
|
2022-11-03 |
2024-06-01 |
美商英塞特公司 |
包含抗gitr抗體之用於治療癌症的組合療法
|
|
WO2024102635A1
(en)
|
2022-11-07 |
2024-05-16 |
Alector Llc |
Uses of siglec-9 ecd fusion molecules in cancer treatment
|
|
KR20250089492A
(ko)
|
2022-11-07 |
2025-06-18 |
네오이뮨텍, 인코퍼레이티드 |
비메틸화된 mgmt 프로모터를 갖는 종양의 치료 방법
|
|
JP2025539816A
(ja)
|
2022-11-21 |
2025-12-09 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
腫瘍浸潤リンパ球の増幅のための2次元プロセス及びそれからの治療法
|
|
AR131141A1
(es)
|
2022-11-22 |
2025-02-19 |
Pic Therapeutics Inc |
Inhibidores de eif4e y usos de los mismos
|
|
AU2023401158A1
(en)
|
2022-12-01 |
2025-05-29 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
|
CN120418289A
(zh)
|
2022-12-14 |
2025-08-01 |
安斯泰来制药欧洲有限公司 |
结合cldn18.2和cd3的双特异性结合剂与免疫检查点抑制剂的联合疗法
|
|
WO2024137776A1
(en)
|
2022-12-21 |
2024-06-27 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
WO2024137865A1
(en)
|
2022-12-22 |
2024-06-27 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
|
CN116077645A
(zh)
*
|
2022-12-28 |
2023-05-09 |
广州誉衡生物科技有限公司 |
抗-pd-1抗体及其在制备治疗非小细胞肺癌患者的药物中的用途
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
CN120813375A
(zh)
|
2023-01-30 |
2025-10-17 |
凯玛布有限公司 |
抗体
|
|
WO2024163477A1
(en)
|
2023-01-31 |
2024-08-08 |
University Of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024184417A1
(en)
|
2023-03-07 |
2024-09-12 |
Photocure Asa |
Therapy for bladder cancer
|
|
WO2024192051A1
(en)
|
2023-03-13 |
2024-09-19 |
Turnstone Biologics Corp. |
Composition of selected tumor infiltrating lymphocytes and related methods of producing and using the same
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024200571A1
(en)
|
2023-03-28 |
2024-10-03 |
Institut National de la Santé et de la Recherche Médicale |
Method for discriminating mono-immunotherapy from combined immunotherapy in cancers
|
|
CN120917143A
(zh)
|
2023-03-29 |
2025-11-07 |
第一三共株式会社 |
抗cd25抗体及抗cd25抗体-药物偶联物
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024223299A2
(en)
|
2023-04-26 |
2024-10-31 |
Isa Pharmaceuticals B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|
|
WO2024228167A1
(en)
|
2023-05-03 |
2024-11-07 |
Iox Therapeutics Inc. |
Inkt cell modulator liposomal compositions and methods of use
|
|
CN121079326A
(zh)
|
2023-05-04 |
2025-12-05 |
诺瓦森塔股份有限公司 |
抗cd161抗体及其使用方法
|
|
CN121057732A
(zh)
|
2023-05-08 |
2025-12-02 |
百时美施贵宝公司 |
经取代的苯基噁唑酮化合物
|
|
AU2024269754A1
(en)
*
|
2023-05-08 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Targeted interferon alpha fusion proteins and methods of use
|
|
WO2024231384A1
(en)
|
2023-05-10 |
2024-11-14 |
Institut National de la Santé et de la Recherche Médicale |
Compositions for treating senescence related disease
|
|
TW202509014A
(zh)
|
2023-05-10 |
2025-03-01 |
美商纜圖藥品公司 |
GSK3α抑制劑及其使用方法
|
|
WO2024245951A1
(en)
|
2023-05-26 |
2024-12-05 |
Institut National de la Santé et de la Recherche Médicale |
Combination of slc8a1 inhibitor and mitochondria-targeted antioxidant for treating melanoma
|
|
WO2024249540A1
(en)
|
2023-05-31 |
2024-12-05 |
Bristol-Myers Squibb Company |
Substituted oxazolone compound for decreasing levels of ikzf1-4 proteins
|
|
WO2024254227A1
(en)
|
2023-06-07 |
2024-12-12 |
Bristol-Myers Squibb Company |
Spirocyclic substituted oxoisoindolinyl piperidine-2,6-dione compound
|
|
WO2024256635A1
(en)
|
2023-06-15 |
2024-12-19 |
Institut National de la Santé et de la Recherche Médicale |
Dpm1 inhibitor for treating cancer
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
EP4620470A3
(en)
|
2023-06-23 |
2025-10-08 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
WO2024263853A1
(en)
|
2023-06-23 |
2024-12-26 |
Bristol-Myers Squibb Company |
Substituted oxoisoindolinyl piperidine-2,6-dione compound as anticancer agent
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Il—18bp拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
WO2025006811A1
(en)
|
2023-06-27 |
2025-01-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025030002A2
(en)
|
2023-08-02 |
2025-02-06 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
TW202521540A
(zh)
|
2023-08-04 |
2025-06-01 |
法商賽諾菲公司 |
咪唑并[4,5-d]嗒𠯤化合物及其接合物、其製備、及其治療應用
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
AR133696A1
(es)
|
2023-09-02 |
2025-10-22 |
Bristol Myers Squibb Co |
Compuestos de fenil oxooxazolil piperidinadiona sustituida
|
|
WO2025064197A1
(en)
|
2023-09-02 |
2025-03-27 |
Bristol-Myers Squibb Company |
Substituted azetidinyl oxoisoindolinyl piperidine-2,6-dione compounds
|
|
KR20250068738A
(ko)
|
2023-09-13 |
2025-05-16 |
브리스톨-마이어스 스큅 컴퍼니 |
치환된 옥소이소인돌리닐 피페리딘-2,6-디온 화합물
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025073765A1
(en)
|
2023-10-03 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from melanoma
|
|
US20250114468A1
(en)
|
2023-10-09 |
2025-04-10 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a combination of a pd1 inhibitor and a targeted immunocytokine
|
|
WO2025080865A1
(en)
|
2023-10-11 |
2025-04-17 |
Turnstone Biologics Corp. |
Combination of tumor infiltrating lymphocytes (til) and low dose radiation
|
|
WO2025078632A1
(en)
|
2023-10-12 |
2025-04-17 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from cancer
|
|
WO2025096638A2
(en)
|
2023-10-30 |
2025-05-08 |
Turnstone Biologics Corp. |
Genetically modified tumor infilitrating lymphocytes and methods of producing and using the same
|
|
WO2025096488A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096505A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096487A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096490A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096494A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096539A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096489A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025106278A1
(en)
|
2023-11-17 |
2025-05-22 |
Mersana Therapeutics, Inc. |
Treatment of cancer using b7-h4-targeted antibody-drug conjugates
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025132479A1
(en)
|
2023-12-18 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Flt3 inhibitor for modulating macrophages polarization
|
|
WO2025132770A1
(en)
|
2023-12-22 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Affitins for the treatment of cancer
|
|
WO2025133389A1
(en)
|
2023-12-22 |
2025-06-26 |
Numab Therapeutics AG |
Antibody binding domains having specificity for lilrb2
|
|
US20250215087A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg depleting agent
|
|
WO2025151487A2
(en)
|
2024-01-08 |
2025-07-17 |
Regents Of The University Of Michigan |
Small-molecule inhibitors of adar1
|
|
US20250269052A1
(en)
|
2024-02-27 |
2025-08-28 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
CN118077649B
(zh)
*
|
2024-02-29 |
2024-09-10 |
复旦大学附属中山医院 |
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|
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