JP6545621B2 - 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法 - Google Patents

遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法 Download PDF

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JP6545621B2
JP6545621B2 JP2015547555A JP2015547555A JP6545621B2 JP 6545621 B2 JP6545621 B2 JP 6545621B2 JP 2015547555 A JP2015547555 A JP 2015547555A JP 2015547555 A JP2015547555 A JP 2015547555A JP 6545621 B2 JP6545621 B2 JP 6545621B2
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JP2016500262A5 (OSRAM
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フェン・ジャン
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Broad Institute Inc
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JP2015547555A 2012-12-12 2013-12-12 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法 Active JP6545621B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201261736527P 2012-12-12 2012-12-12
US61/736,527 2012-12-12
US201361748427P 2013-01-02 2013-01-02
US61/748,427 2013-01-02
US201361791409P 2013-03-15 2013-03-15
US61/791,409 2013-03-15
US201361835931P 2013-06-17 2013-06-17
US61/835,931 2013-06-17
US201361842322P 2013-07-02 2013-07-02
US61/842,322 2013-07-02
US14/054,414 2013-10-15
US14/054,414 US8697359B1 (en) 2012-12-12 2013-10-15 CRISPR-Cas systems and methods for altering expression of gene products
PCT/US2013/074743 WO2014093661A2 (en) 2012-12-12 2013-12-12 Crispr-cas systems and methods for altering expression of gene products

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JP2016128599A Division JP6723094B2 (ja) 2012-12-12 2016-06-29 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法
JP2019035911A Division JP6870015B2 (ja) 2012-12-12 2019-02-28 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法

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JP2016500262A JP2016500262A (ja) 2016-01-12
JP2016500262A5 JP2016500262A5 (OSRAM) 2017-02-16
JP6545621B2 true JP6545621B2 (ja) 2019-07-17

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JP2015547555A Active JP6545621B2 (ja) 2012-12-12 2013-12-12 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法
JP2016128599A Active JP6723094B2 (ja) 2012-12-12 2016-06-29 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法
JP2019035911A Active JP6870015B2 (ja) 2012-12-12 2019-02-28 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法
JP2021068300A Active JP7090775B2 (ja) 2012-12-12 2021-04-14 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法
JP2022095742A Active JP7463436B2 (ja) 2012-12-12 2022-06-14 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法
JP2024050615A Pending JP2024088668A (ja) 2012-12-12 2024-03-27 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法

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JP2019035911A Active JP6870015B2 (ja) 2012-12-12 2019-02-28 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ−Ｃａｓ系および方法
JP2021068300A Active JP7090775B2 (ja) 2012-12-12 2021-04-14 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法
JP2022095742A Active JP7463436B2 (ja) 2012-12-12 2022-06-14 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法
JP2024050615A Pending JP2024088668A (ja) 2012-12-12 2024-03-27 遺伝子産物の発現を変更するためのＣＲＩＳＰＲ－Ｃａｓ系および方法

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US (8) US8697359B1 (OSRAM)
EP (2) EP2998400A1 (OSRAM)
JP (6) JP6545621B2 (OSRAM)
KR (1) KR20150107739A (OSRAM)
CN (4) CN106170549B (OSRAM)
AU (5) AU2013359238B2 (OSRAM)
BR (1) BR112015013785A2 (OSRAM)
CA (1) CA2894688A1 (OSRAM)
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PT (1) PT2764103E (OSRAM)
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US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
WO2011156723A1 (en) 2010-06-11 2011-12-15 Regeneron Pharmaceuticals, Inc. Production of fertile xy female animals from xy es cells
US11273187B2 (en) 2015-11-30 2022-03-15 Joseph E. Kovarik Method and system for reducing the likelihood of developing depression in an individual
US10512661B2 (en) 2011-02-04 2019-12-24 Joseph E. Kovarik Method and system for reducing the likelihood of developing liver cancer in an individual diagnosed with non-alcoholic fatty liver disease
US9730967B2 (en) 2011-02-04 2017-08-15 Katherine Rose Kovarik Method and system for treating cancer cachexia
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US10583033B2 (en) 2011-02-04 2020-03-10 Katherine Rose Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US11419903B2 (en) 2015-11-30 2022-08-23 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11191665B2 (en) 2011-02-04 2021-12-07 Joseph E. Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
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