HK1246690A1 - 用於鑒定高度特異性核酸酶的方法和組合物 - Google Patents

用於鑒定高度特異性核酸酶的方法和組合物

Info

Publication number
HK1246690A1
HK1246690A1 HK18106468.0A HK18106468A HK1246690A1 HK 1246690 A1 HK1246690 A1 HK 1246690A1 HK 18106468 A HK18106468 A HK 18106468A HK 1246690 A1 HK1246690 A1 HK 1246690A1
Authority
HK
Hong Kong
Prior art keywords
compositions
identification
methods
highly specific
specific nucleases
Prior art date
Application number
HK18106468.0A
Other languages
English (en)
Inventor
Jeffrey C Miller
Marcus B Noyes
Original Assignee
Sangamo Therapeutics Inc
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sangamo Therapeutics Inc, Univ Princeton filed Critical Sangamo Therapeutics Inc
Publication of HK1246690A1 publication Critical patent/HK1246690A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
HK18106468.0A 2015-01-21 2018-05-18 用於鑒定高度特異性核酸酶的方法和組合物 HK1246690A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562106042P 2015-01-21 2015-01-21
US201562212805P 2015-09-01 2015-09-01
PCT/US2016/014283 WO2016118726A2 (en) 2015-01-21 2016-01-21 Methods and compositions for identification of highly specific nucleases

Publications (1)

Publication Number Publication Date
HK1246690A1 true HK1246690A1 (zh) 2018-09-14

Family

ID=56417921

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106468.0A HK1246690A1 (zh) 2015-01-21 2018-05-18 用於鑒定高度特異性核酸酶的方法和組合物

Country Status (4)

Country Link
US (1) US20180002379A1 (zh)
EP (1) EP3247366A4 (zh)
HK (1) HK1246690A1 (zh)
WO (1) WO2016118726A2 (zh)

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WO2017223127A1 (en) * 2016-06-21 2017-12-28 President And Fellows Of Harvard College Frequency-based modulation of diverse species in a nucleic acid library
TW201839136A (zh) 2017-02-06 2018-11-01 瑞士商諾華公司 治療血色素異常症之組合物及方法
WO2019014564A1 (en) 2017-07-14 2019-01-17 Editas Medicine, Inc. SYSTEMS AND METHODS OF TARGETED INTEGRATION AND GENOME EDITING AND DETECTION THEREOF WITH INTEGRATED PRIMING SITES
BR112020016524A2 (pt) 2018-02-14 2021-09-28 Deep Genomics Incorporated Terapia com oligonucleotídeos para a doença de wilson
CN110944350B (zh) * 2018-09-21 2021-11-30 展讯通信（上海）有限公司 拥塞控制系数获取方法及用户终端、计算机可读存储介质
CN113257346B (zh) * 2021-06-28 2021-10-19 北京橡鑫生物科技有限公司 一种基于低深度WGS评估HRD score的方法
CN114606322B (zh) * 2022-04-21 2023-07-28 中国人民解放军陆军军医大学第一附属医院 基于Argonaute蛋白和指数扩增一步检测长链RNA的试剂盒及检测方法及应用

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Also Published As

Publication number Publication date
WO2016118726A2 (en) 2016-07-28
EP3247366A4 (en) 2018-10-31
US20180002379A1 (en) 2018-01-04
WO2016118726A3 (en) 2016-09-22
EP3247366A2 (en) 2017-11-29

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