JP5624276B2 - 抗体の血中動態を制御する方法 - Google Patents

抗体の血中動態を制御する方法 Download PDF

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JP5624276B2
JP5624276B2 JP2008508646A JP2008508646A JP5624276B2 JP 5624276 B2 JP5624276 B2 JP 5624276B2 JP 2008508646 A JP2008508646 A JP 2008508646A JP 2008508646 A JP2008508646 A JP 2008508646A JP 5624276 B2 JP5624276 B2 JP 5624276B2
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antibody
amino acid
blood
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humanized
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JPWO2007114319A1 (ja
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智之 井川
智之 井川
角田　浩行
浩行 角田
橘　達彦
達彦 橘
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Chugai Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2008508646A 2006-03-31 2007-03-30 抗体の血中動態を制御する方法 Active JP5624276B2 (ja)

Priority Applications (1)

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JP2008508646A JP5624276B2 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法

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JP2006097796 2006-03-31
JP2006097796 2006-03-31
PCT/JP2007/057036 WO2007114319A1 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法
JP2008508646A JP5624276B2 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法

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JP5624276B2 true JP5624276B2 (ja) 2014-11-12

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JP2013048910A Active JP5882247B2 (ja) 2006-03-31 2013-03-12 抗体の血中動態を制御する方法
JP2015081671A Active JP6158852B2 (ja) 2006-03-31 2015-04-13 抗体の血中動態を制御する方法
JP2017034246A Active JP6585106B2 (ja) 2006-03-31 2017-02-27 抗体の血中動態を制御する方法

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JP2015081671A Active JP6158852B2 (ja) 2006-03-31 2015-04-13 抗体の血中動態を制御する方法
JP2017034246A Active JP6585106B2 (ja) 2006-03-31 2017-02-27 抗体の血中動態を制御する方法

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US (2) US11046784B2 (https=)
EP (4) EP3056568B1 (https=)
JP (4) JP5624276B2 (https=)
KR (1) KR101463631B1 (https=)
CN (2) CN104761637B (https=)
AU (1) AU2007232873B2 (https=)
CA (1) CA2647846C (https=)
DK (2) DK3056568T3 (https=)
ES (2) ES2892925T3 (https=)
IN (1) IN2014DN10515A (https=)
WO (1) WO2007114319A1 (https=)

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* Cited by examiner, † Cited by third party
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