DK1069185T3 - Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof - Google Patents

Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof

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Publication number
DK1069185T3
DK1069185T3 DK99912098.3T DK99912098T DK1069185T3 DK 1069185 T3 DK1069185 T3 DK 1069185T3 DK 99912098 T DK99912098 T DK 99912098T DK 1069185 T3 DK1069185 T3 DK 1069185T3
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DK
Denmark
Prior art keywords
chain
humanized antibody
region
humanized
antibody
Prior art date
Application number
DK99912098.3T
Other languages
English (en)
Inventor
Koh Chugai Sato
Hideki Adachi
Naohiro Yabuta
Original Assignee
Chugai Pharmaceutical Co Ltd
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Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
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Publication of DK1069185T3 publication Critical patent/DK1069185T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99912098.3T 1998-04-03 1999-04-02 Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof DK1069185T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9185098 1998-04-03
PCT/JP1999/001768 WO1999051743A1 (en) 1998-04-03 1999-04-02 Humanized antibody against human tissue factor (tf) and process for constructing humanized antibody

Publications (1)

Publication Number Publication Date
DK1069185T3 true DK1069185T3 (da) 2011-06-27

Family

ID=14038058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99912098.3T DK1069185T3 (da) 1998-04-03 1999-04-02 Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof

Country Status (19)

Country Link
US (2) US6677436B1 (da)
EP (2) EP2363484A3 (da)
JP (2) JP3998419B2 (da)
KR (1) KR20010042435A (da)
CN (1) CN1303431A (da)
AT (1) ATE512225T1 (da)
AU (1) AU752730B2 (da)
BR (1) BR9909382A (da)
CA (1) CA2325346A1 (da)
DK (1) DK1069185T3 (da)
ES (1) ES2364266T3 (da)
HU (1) HUP0101160A2 (da)
IL (1) IL138801A0 (da)
NO (1) NO20004946L (da)
PL (1) PL343322A1 (da)
PT (1) PT1069185E (da)
SK (1) SK14812000A3 (da)
TR (2) TR200002885T2 (da)
WO (1) WO1999051743A1 (da)

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US6677436B1 (en) 2004-01-13
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