JP3444885B2 - Ｌ鎖欠落免疫グロブリン - Google Patents

Ｌ鎖欠落免疫グロブリン

Info

Publication number
JP3444885B2
JP3444885B2 JP50590394A JP50590394A JP3444885B2 JP 3444885 B2 JP3444885 B2 JP 3444885B2 JP 50590394 A JP50590394 A JP 50590394A JP 50590394 A JP50590394 A JP 50590394A JP 3444885 B2 JP3444885 B2 JP 3444885B2
Authority
JP
Japan
Prior art keywords
immunoglobulin
chain
domain
dna
immunoglobulins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP50590394A
Other languages
English (en)
Japanese (ja)
Other versions
JPH08500487A (ja
Inventor
カステルマン，セシレ
ハメルス，ライモンド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vrije Universiteit Brussel VUB
Original Assignee
Vrije Universiteit Brussel VUB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26132410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP3444885(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP92402326A external-priority patent/EP0584421A1/en
Application filed by Vrije Universiteit Brussel VUB filed Critical Vrije Universiteit Brussel VUB
Publication of JPH08500487A publication Critical patent/JPH08500487A/ja
Application granted granted Critical
Publication of JP3444885B2 publication Critical patent/JP3444885B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP50590394A 1992-08-21 1993-08-18 Ｌ鎖欠落免疫グロブリン Expired - Fee Related JP3444885B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP92402326.0 1992-08-21
EP92402326A EP0584421A1 (en) 1992-08-21 1992-08-21 Immunoglobulins devoid of light chains
EP93401310.3 1993-05-21
EP93401310 1993-05-21
PCT/EP1993/002214 WO1994004678A1 (en) 1992-08-21 1993-08-18 Immunoglobulins devoid of light chains

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2001136457A Division JP3660270B2 (ja) 1992-08-21 2001-05-07 Ｌ鎖欠落免疫グロブリン

Publications (2)

Publication Number Publication Date
JPH08500487A JPH08500487A (ja) 1996-01-23
JP3444885B2 true JP3444885B2 (ja) 2003-09-08

Family

ID=26132410

Family Applications (4)

Application Number Title Priority Date Filing Date
JP50590394A Expired - Fee Related JP3444885B2 (ja) 1992-08-21 1993-08-18 Ｌ鎖欠落免疫グロブリン
JP2001136457A Expired - Lifetime JP3660270B2 (ja) 1992-08-21 2001-05-07 Ｌ鎖欠落免疫グロブリン
JP2005010359A Expired - Lifetime JP4414900B2 (ja) 1992-08-21 2005-01-18 Ｌ鎖欠落免疫グロブリン
JP2009192382A Pending JP2009280608A (ja) 1992-08-21 2009-08-21 Ｌ鎖欠落免疫グロブリン

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2001136457A Expired - Lifetime JP3660270B2 (ja) 1992-08-21 2001-05-07 Ｌ鎖欠落免疫グロブリン
JP2005010359A Expired - Lifetime JP4414900B2 (ja) 1992-08-21 2005-01-18 Ｌ鎖欠落免疫グロブリン
JP2009192382A Pending JP2009280608A (ja) 1992-08-21 2009-08-21 Ｌ鎖欠落免疫グロブリン

Country Status (13)

Country Link
US (5) US5759808A (cg-RX-API-DMAC7.html)
EP (6) EP1498427B1 (cg-RX-API-DMAC7.html)
JP (4) JP3444885B2 (cg-RX-API-DMAC7.html)
AT (5) ATE427968T1 (cg-RX-API-DMAC7.html)
AU (1) AU701578B2 (cg-RX-API-DMAC7.html)
CA (1) CA2142331C (cg-RX-API-DMAC7.html)
DE (6) DE69334305D1 (cg-RX-API-DMAC7.html)
DK (5) DK1589107T3 (cg-RX-API-DMAC7.html)
ES (5) ES2325541T3 (cg-RX-API-DMAC7.html)
FI (3) FI115462B (cg-RX-API-DMAC7.html)
GR (1) GR3037024T3 (cg-RX-API-DMAC7.html)
PT (5) PT1498427E (cg-RX-API-DMAC7.html)
WO (1) WO1994004678A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1319)

* Cited by examiner, † Cited by third party
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ATE374248T1 (de) * 1996-06-27 2007-10-15 Vlaams Interuniv Inst Biotech Antikörpermoleküle, die spezifisch mit dem aktiven zentrum oder dem aktiven spalt eines zielmoleküls interagieren
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