UA121192C2 - Спосіб отримання хімічних сполук, які модулюють активність рі3-кінази - Google Patents

Спосіб отримання хімічних сполук, які модулюють активність рі3-кінази Download PDF

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Publication number
UA121192C2
UA121192C2 UAA201504678A UAA201504678A UA121192C2 UA 121192 C2 UA121192 C2 UA 121192C2 UA A201504678 A UAA201504678 A UA A201504678A UA A201504678 A UAA201504678 A UA A201504678A UA 121192 C2 UA121192 C2 UA 121192C2
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Ukraine
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formula
compound
substituted
unsubstituted
alkyl
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UAA201504678A
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English (en)
Ukrainian (uk)
Inventor
Пінґда Рен
Йі Ліу
Трой Едвард Вілсон
Ляншен Лі
Катріна Чан
Крістіан Роммель
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Інтеллікіне Ллк
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Publication of UA121192C2 publication Critical patent/UA121192C2/uk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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  • Pharmacology & Pharmacy (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
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  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
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  • Radiology & Medical Imaging (AREA)
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  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
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UAA201504678A 2009-07-15 2010-07-15 Спосіб отримання хімічних сполук, які модулюють активність рі3-кінази UA121192C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof

Publications (1)

Publication Number Publication Date
UA121192C2 true UA121192C2 (uk) 2020-04-27

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UAA201115546A UA109878C2 (uk) 2009-07-15 2010-07-15 Похідні ізохінолінону, фармацевтична композиція на їх основі (варіанти) та спосіб лікування захворювань (варіанти)
UAA201504678A UA121192C2 (uk) 2009-07-15 2010-07-15 Спосіб отримання хімічних сполук, які модулюють активність рі3-кінази

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UAA201115546A UA109878C2 (uk) 2009-07-15 2010-07-15 Похідні ізохінолінону, фармацевтична композиція на їх основі (варіанти) та спосіб лікування захворювань (варіанти)

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US (13) US8193182B2 (show.php)
EP (4) EP2456444B1 (show.php)
JP (2) JP5944313B2 (show.php)
KR (1) KR101680406B1 (show.php)
CN (3) CN109912599B (show.php)
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DK (1) DK2456444T3 (show.php)
ES (1) ES2538853T3 (show.php)
FI (1) FIC20210039I1 (show.php)
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HU (1) HUS2100048I1 (show.php)
IL (2) IL217181A (show.php)
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