JP5624276B2 - 抗体の血中動態を制御する方法 - Google Patents

抗体の血中動態を制御する方法 Download PDF

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JP5624276B2
JP5624276B2 JP2008508646A JP2008508646A JP5624276B2 JP 5624276 B2 JP5624276 B2 JP 5624276B2 JP 2008508646 A JP2008508646 A JP 2008508646A JP 2008508646 A JP2008508646 A JP 2008508646A JP 5624276 B2 JP5624276 B2 JP 5624276B2
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antibody
amino acid
blood
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humanized
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JPWO2007114319A1 (ja
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智之 井川
智之 井川
角田　浩行
浩行 角田
橘　達彦
達彦 橘
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Chugai Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2008508646A 2006-03-31 2007-03-30 抗体の血中動態を制御する方法 Active JP5624276B2 (ja)

Priority Applications (1)

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JP2008508646A JP5624276B2 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法

Applications Claiming Priority (4)

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JP2006097796 2006-03-31
JP2006097796 2006-03-31
JP2008508646A JP5624276B2 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法
PCT/JP2007/057036 WO2007114319A1 (ja) 2006-03-31 2007-03-30 抗体の血中動態を制御する方法

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JP5624276B2 true JP5624276B2 (ja) 2014-11-12

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JP2013048910A Active JP5882247B2 (ja) 2006-03-31 2013-03-12 抗体の血中動態を制御する方法
JP2015081671A Active JP6158852B2 (ja) 2006-03-31 2015-04-13 抗体の血中動態を制御する方法
JP2017034246A Active JP6585106B2 (ja) 2006-03-31 2017-02-27 抗体の血中動態を制御する方法

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JP2015081671A Active JP6158852B2 (ja) 2006-03-31 2015-04-13 抗体の血中動態を制御する方法
JP2017034246A Active JP6585106B2 (ja) 2006-03-31 2017-02-27 抗体の血中動態を制御する方法

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US (2) US11046784B2 (enExample)
EP (4) EP3056568B1 (enExample)
JP (4) JP5624276B2 (enExample)
KR (1) KR101463631B1 (enExample)
CN (2) CN101479381B (enExample)
AU (1) AU2007232873B2 (enExample)
CA (1) CA2647846C (enExample)
DK (2) DK3056568T3 (enExample)
ES (2) ES2892925T3 (enExample)
IN (1) IN2014DN10515A (enExample)
WO (1) WO2007114319A1 (enExample)

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* Cited by examiner, † Cited by third party
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