BR1101078A - Composto - Google Patents

Composto

Info

Publication number
BR1101078A
BR1101078A BR1101078-9A BR1101078A BR1101078A BR 1101078 A BR1101078 A BR 1101078A BR 1101078 A BR1101078 A BR 1101078A BR 1101078 A BR1101078 A BR 1101078A
Authority
BR
Brazil
Prior art keywords
carrier
conjugates
well
antitumor antibiotics
analogs
Prior art date
Application number
BR1101078-9A
Other languages
English (en)
Inventor
Philip Ross Hamann
Lois Hinman
Irwin Hollander
Ryan Holcomb
William Hallett
Hwei-Ru Tsou
Martin J Weiss
Original Assignee
Philip Ross Hamann
Lois Hinman
Irwin Hollander
Ryan Holcomb
William Hallett
Hwei-Ru Tsou
Martin J. Weiss
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22962074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR1101078(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Philip Ross Hamann, Lois Hinman, Irwin Hollander, Ryan Holcomb, William Hallett, Hwei-Ru Tsou, Martin J. Weiss filed Critical Philip Ross Hamann
Publication of BR1101078A publication Critical patent/BR1101078A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR1101078-9A 1994-06-03 1997-05-14 Composto BR1101078A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/253,877 US5773001A (en) 1994-06-03 1994-06-03 Conjugates of methyltrithio antitumor agents and intermediates for their synthesis

Publications (1)

Publication Number Publication Date
BR1101078A true BR1101078A (pt) 1999-10-26

Family

ID=22962074

Family Applications (2)

Application Number Title Priority Date Filing Date
BR1101078-9A BR1101078A (pt) 1994-06-03 1997-05-14 Composto
BR1100990-0A BR1100990A (pt) 1994-06-03 1997-05-14 processo para preparar os derivados marcados

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR1100990-0A BR1100990A (pt) 1994-06-03 1997-05-14 processo para preparar os derivados marcados

Country Status (20)

Country Link
US (4) US5773001A (pt)
EP (1) EP0689845B1 (pt)
JP (2) JP3650165B2 (pt)
KR (1) KR100408376B1 (pt)
AT (1) ATE223234T1 (pt)
AU (1) AU697280B2 (pt)
BR (2) BR1101078A (pt)
CA (1) CA2150785C (pt)
CY (1) CY2334B1 (pt)
DE (1) DE69528016T2 (pt)
DK (1) DK0689845T3 (pt)
ES (1) ES2181752T3 (pt)
FI (1) FI117690B (pt)
IL (1) IL113984A (pt)
NO (1) NO313617B1 (pt)
NZ (3) NZ272274A (pt)
PT (1) PT689845E (pt)
SI (1) SI0689845T1 (pt)
TW (1) TW394778B (pt)
ZA (1) ZA954570B (pt)

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* Cited by examiner, † Cited by third party
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