MX2022004443A - Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes. - Google Patents

Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes.

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Publication number
MX2022004443A
MX2022004443A MX2022004443A MX2022004443A MX2022004443A MX 2022004443 A MX2022004443 A MX 2022004443A MX 2022004443 A MX2022004443 A MX 2022004443A MX 2022004443 A MX2022004443 A MX 2022004443A MX 2022004443 A MX2022004443 A MX 2022004443A
Authority
MX
Mexico
Prior art keywords
methods
cell lymphoma
diffuse large
treat diffuse
cd79b immunoconjugates
Prior art date
Application number
MX2022004443A
Other languages
English (en)
Inventor
Jamie Harue Hirata
Montalvo Juana Elva Hernandez
Naseer Ul Din Qayum
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2022004443A publication Critical patent/MX2022004443A/es

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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Abstract

En la presente se proporcionan métodos para tratar trastornos proliferativos de linfocitos B (tal como linfoma difuso de linfocitos B grandes (DLBCL)) usando inmunoconjugados que comprenden anticuerpos anti-CD79b en combinación con un anticuerpo anti-CD20 (tal como rituximab) y uno o más agentes quimioterapéuticos (tal como gemcitabina y oxaliplatino).
MX2022004443A 2019-10-18 2020-06-09 Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes. MX2022004443A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962923359P 2019-10-18 2019-10-18
PCT/US2020/036796 WO2021076196A1 (en) 2019-10-18 2020-06-09 Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma

Publications (1)

Publication Number Publication Date
MX2022004443A true MX2022004443A (es) 2022-05-02

Family

ID=71944219

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004443A MX2022004443A (es) 2019-10-18 2020-06-09 Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes.

Country Status (14)

Country Link
EP (1) EP4045090A1 (es)
JP (2) JP7413519B2 (es)
KR (1) KR20220086618A (es)
CN (3) CN118557750A (es)
AU (1) AU2020365836A1 (es)
BR (1) BR112022007216A2 (es)
CA (1) CA3153880A1 (es)
CL (1) CL2022000950A1 (es)
CR (1) CR20220166A (es)
IL (1) IL292235A (es)
MX (1) MX2022004443A (es)
PE (1) PE20221039A1 (es)
TW (1) TW202122114A (es)
WO (1) WO2021076196A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022273063A1 (en) * 2021-05-12 2023-11-23 Genentech, Inc. Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
CN118271439A (zh) * 2022-12-29 2024-07-02 深圳泽安生物医药有限公司 抗CD79b抗体及其用途
CN116535509B (zh) * 2023-06-28 2023-11-03 上海偌妥生物科技有限公司 抗CD79b抗体、其制备方法及其应用

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