JP5944313B2 - 特定の化学物質、組成物および方法 - Google Patents

特定の化学物質、組成物および方法 Download PDF

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JP5944313B2
JP5944313B2 JP2012520630A JP2012520630A JP5944313B2 JP 5944313 B2 JP5944313 B2 JP 5944313B2 JP 2012520630 A JP2012520630 A JP 2012520630A JP 2012520630 A JP2012520630 A JP 2012520630A JP 5944313 B2 JP5944313 B2 JP 5944313B2
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compound
cancer
formula
substituted
acid
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JP2012533541A (ja
JP2012533541A5 (enExample
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ピンダ レン，
ピンダ レン，
イー リュー，
イー リュー，
トロイ エドワード ウィルソン，
トロイ エドワード ウィルソン，
リャンシェン リー，
リャンシェン リー，
カトリーナ チャン，
カトリーナ チャン，
クリスチャン ロメル，
クリスチャン ロメル，
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インテリカイン， エルエルシー
インテリカイン， エルエルシー
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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JP2012520630A 2009-07-15 2010-07-15 特定の化学物質、組成物および方法 Active JP5944313B2 (ja)

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Application Number Priority Date Filing Date Title
US12/503,776 2009-07-15
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
PCT/US2010/002020 WO2011008302A1 (en) 2009-07-15 2010-07-15 Certain chemical entities, compositions and methods

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JP2016103832A Division JP6158395B2 (ja) 2009-07-15 2016-05-25 特定の化学物質、組成物および方法

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JP2012533541A JP2012533541A (ja) 2012-12-27
JP2012533541A5 JP2012533541A5 (enExample) 2016-03-17
JP5944313B2 true JP5944313B2 (ja) 2016-07-05

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US (13) US8193182B2 (enExample)
EP (4) EP2918589B1 (enExample)
JP (2) JP5944313B2 (enExample)
KR (1) KR101680406B1 (enExample)
CN (3) CN106188059B (enExample)
AU (1) AU2010274075B2 (enExample)
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US20180098983A1 (en) 2018-04-12
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RU2746319C2 (ru) 2021-04-12
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RU2582676C3 (ru) 2022-01-17
LTC2456444I2 (enExample) 2024-11-25
CN102711767A (zh) 2012-10-03
MX351028B (es) 2017-09-28
CN109912599B (zh) 2021-11-02
AU2010274075A1 (en) 2012-02-09
JP6158395B2 (ja) 2017-07-05
CN106188059B (zh) 2019-02-01
US9655892B2 (en) 2017-05-23
MY175979A (en) 2020-07-19
NL301140I2 (nl) 2021-11-15
EP2456444A4 (en) 2012-12-05
PH12020550450A1 (en) 2021-06-07
KR20120097479A (ko) 2012-09-04
CA2768307C (en) 2018-02-13
US11433065B2 (en) 2022-09-06
HK1213257A1 (en) 2016-06-30
JP2016210781A (ja) 2016-12-15
CA2768307A1 (en) 2011-01-20
IL217181A (en) 2016-02-29
MX2012000626A (es) 2012-03-26
RU2016110024A (ru) 2018-11-23
DK2456444T3 (en) 2015-05-11
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US8193182B2 (en) 2012-06-05
EP3150609A1 (en) 2017-04-05
SG10201503886WA (en) 2015-06-29
US20130345216A1 (en) 2013-12-26
PT2456444E (pt) 2015-06-09
NO2021047I1 (no) 2021-11-10
US20120149701A1 (en) 2012-06-14
US9216982B2 (en) 2015-12-22
HUS2100048I1 (hu) 2021-12-28
BR112012000968B1 (pt) 2021-05-04
SI2456444T1 (sl) 2015-07-31
US20160158239A1 (en) 2016-06-09
ZA201200254B (en) 2013-03-27
PL2456444T3 (pl) 2015-08-31
MY168762A (en) 2018-12-04
US20090312319A1 (en) 2009-12-17
US20160031886A1 (en) 2016-02-04
FIC20210039I1 (fi) 2021-11-03
CY1116424T1 (el) 2017-02-08
CN106188059A (zh) 2016-12-07
IN2012DN00943A (enExample) 2015-04-10
RU2016110024A3 (enExample) 2019-09-10
US20250170122A1 (en) 2025-05-29
IL243932A0 (en) 2016-04-21
NZ597595A (en) 2014-08-29
EP2456444A1 (en) 2012-05-30
MX379814B (es) 2025-03-11
US20170281614A1 (en) 2017-10-05
BR112012000968B8 (pt) 2021-05-25
KR101680406B1 (ko) 2016-11-29
US20140341894A1 (en) 2014-11-20
US8785456B2 (en) 2014-07-22
BR112012000968A2 (pt) 2017-12-05
UA121192C2 (uk) 2020-04-27
AU2010274075B2 (en) 2015-01-22
IL243932A (en) 2016-11-30
LTPA2021526I1 (enExample) 2021-12-10
UA109878C2 (uk) 2015-10-26
CN102711767B (zh) 2016-08-03
WO2011008302A1 (en) 2011-01-20
US9522146B2 (en) 2016-12-20
US20190290636A1 (en) 2019-09-26
EP3441392B1 (en) 2021-12-15
PH12015502432A1 (en) 2017-01-16
NL301140I1 (enExample) 2021-11-03

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