ES2115732T3 - Inhibidor tumoral tetrapeptidico que incluye en su estructura fenetilamidas modificadas. - Google Patents

Inhibidor tumoral tetrapeptidico que incluye en su estructura fenetilamidas modificadas.

Info

Publication number
ES2115732T3
ES2115732T3 ES93309707T ES93309707T ES2115732T3 ES 2115732 T3 ES2115732 T3 ES 2115732T3 ES 93309707 T ES93309707 T ES 93309707T ES 93309707 T ES93309707 T ES 93309707T ES 2115732 T3 ES2115732 T3 ES 2115732T3
Authority
ES
Spain
Prior art keywords
fenetilamidas
tetrapeptidic
structure modified
tumor inhibitor
tetrapeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93309707T
Other languages
English (en)
Other versions
ES2115732T5 (es
Inventor
George R Pettit
Jozsef Barkoczy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arizona
Original Assignee
University of Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25531834&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2115732(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of Arizona filed Critical University of Arizona
Application granted granted Critical
Publication of ES2115732T3 publication Critical patent/ES2115732T3/es
Publication of ES2115732T5 publication Critical patent/ES2115732T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE HAN DILUCIDADO Y SINTETIZADO NUEVAS FENOETILAMIDAS MODIFICADAS QUE CONTIENEN TETRAPEPTIDOS Y SON UNICAS EN SU ESPECIE Y SE HA DESCUBIERTO QUE PRESENTAN EFECTOS INHIBIDORES DE TUMORES CUANDO SE COMPARAN CON LA PANTALLA DE NCI DE LOS SEIS TIPOS PRINCIPALES DE CANCERES HUMANOS Y CON LA LINEA CELULAR LINFOCITICA P388 DE LA MURINA. LAS NUEVAS FENOTILAMIDAS DE TETRAPEPTIDOS MODIFICADAS SON 6(A
ES93309707T 1992-12-03 1993-12-03 Inhibidor tumoral tetrapeptidico que incluye en su estructura fenetilamidas modificadas. Expired - Lifetime ES2115732T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US985827 1992-12-03
US07/985,827 US5635483A (en) 1992-12-03 1992-12-03 Tumor inhibiting tetrapeptide bearing modified phenethyl amides

Publications (2)

Publication Number Publication Date
ES2115732T3 true ES2115732T3 (es) 1998-07-01
ES2115732T5 ES2115732T5 (es) 2005-03-01

Family

ID=25531834

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93309707T Expired - Lifetime ES2115732T5 (es) 1992-12-03 1993-12-03 Inhibidor tumoral tetrapeptidico que incluye en su estructura fenetilamidas modificadas.

Country Status (7)

Country Link
US (1) US5635483A (es)
EP (1) EP0600744B2 (es)
JP (1) JP3430316B2 (es)
AT (1) ATE163650T1 (es)
CA (1) CA2110555C (es)
DE (1) DE69317226T3 (es)
ES (1) ES2115732T5 (es)

Families Citing this family (730)

* Cited by examiner, † Cited by third party
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JPH0770173A (ja) 1995-03-14
DE69317226D1 (de) 1998-04-09
DE69317226T2 (de) 1998-07-16
EP0600744B1 (en) 1998-03-04
EP0600744B2 (en) 2004-06-30
JP3430316B2 (ja) 2003-07-28
EP0600744A1 (en) 1994-06-08

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