SG11202011633SA - Psma binding agents and uses thereof - Google Patents

Psma binding agents and uses thereof

Info

Publication number
SG11202011633SA
SG11202011633SA SG11202011633SA SG11202011633SA SG11202011633SA SG 11202011633S A SG11202011633S A SG 11202011633SA SG 11202011633S A SG11202011633S A SG 11202011633SA SG 11202011633S A SG11202011633S A SG 11202011633SA SG 11202011633S A SG11202011633S A SG 11202011633SA
Authority
SG
Singapore
Prior art keywords
binding agents
psma binding
psma
agents
binding
Prior art date
Application number
SG11202011633SA
Inventor
Glenn Mark Anderson
Tammy Bush
Cardoso Rosa Maria Fernandes
Ellen Chi
Judith Ann Connor
Thai Quang Dinh
Derrick Lemon Domingo
John Michael Jones
Colleen Kane
Bethany Kay Mattson
Theresa Marie Mcdevitt
Jill Marie Mooney
Richard Stephen Tawadros
Hong Mimi Zhou
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of SG11202011633SA publication Critical patent/SG11202011633SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
SG11202011633SA 2018-05-24 2019-05-21 Psma binding agents and uses thereof SG11202011633SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862676099P 2018-05-24 2018-05-24
PCT/IB2019/054189 WO2019224718A2 (en) 2018-05-24 2019-05-21 Psma binding agents and uses thereof

Publications (1)

Publication Number Publication Date
SG11202011633SA true SG11202011633SA (en) 2020-12-30

Family

ID=67253934

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011633SA SG11202011633SA (en) 2018-05-24 2019-05-21 Psma binding agents and uses thereof

Country Status (25)

Country Link
US (1) US11746157B2 (en)
EP (1) EP3802609A2 (en)
JP (1) JP7361727B2 (en)
KR (1) KR20210015902A (en)
CN (1) CN112513085A (en)
AR (1) AR116173A1 (en)
AU (1) AU2019274657A1 (en)
BR (1) BR112020023872A2 (en)
CA (1) CA3101272A1 (en)
CL (1) CL2020003031A1 (en)
CR (1) CR20200563A (en)
DO (1) DOP2020000216A (en)
EA (1) EA202092839A1 (en)
EC (1) ECSP20082991A (en)
IL (1) IL278888A (en)
JO (1) JOP20200303A1 (en)
MA (1) MA52777A (en)
MX (1) MX2020012598A (en)
NI (1) NI202000086A (en)
PE (1) PE20211916A1 (en)
PH (1) PH12020551997A1 (en)
SG (1) SG11202011633SA (en)
TW (1) TW202016135A (en)
UY (1) UY38244A (en)
WO (1) WO2019224718A2 (en)

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CA3136892A1 (en) * 2019-04-19 2020-10-22 Janssen Biotech, Inc. Methods of treating renal cancer with an anti- psma/cd3 antibody
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BR112021022237A2 (en) 2019-05-10 2022-03-29 Janssen Biotech Inc Macrocyclic chelators and methods of using them
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US20230073821A1 (en) * 2021-08-27 2023-03-09 International Business Machines Corporation Antigen-binding proteins targeting coronavirus (cov) variants
WO2023084396A1 (en) 2021-11-09 2023-05-19 Janssen Biotech, Inc. Macrocyclic compounds and methods of making the same
WO2023084397A1 (en) 2021-11-09 2023-05-19 Janssen Biotech, Inc. Macrocyclic compounds and diagnostic uses thereof
WO2023152581A1 (en) 2022-02-09 2023-08-17 Janssen Biotech, Inc. Method of treating cancer with psmaxcd3 antibody
WO2023183231A1 (en) 2022-03-21 2023-09-28 Amgen Inc. Combination therapy methods with t-cell engaging molecules for treatment of prostate cancer
WO2023198015A1 (en) * 2022-04-11 2023-10-19 江苏恒瑞医药股份有限公司 Antigen-binding molecule specifically binding to psma and cd28 and pharmaceutical use thereof

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Also Published As

Publication number Publication date
EA202092839A1 (en) 2021-02-12
AR116173A1 (en) 2021-04-07
JP7361727B2 (en) 2023-10-16
US11746157B2 (en) 2023-09-05
IL278888A (en) 2021-01-31
EP3802609A2 (en) 2021-04-14
PE20211916A1 (en) 2021-09-28
WO2019224718A3 (en) 2020-03-05
CR20200563A (en) 2021-05-11
AU2019274657A1 (en) 2020-12-10
CA3101272A1 (en) 2019-11-28
MA52777A (en) 2021-04-14
KR20210015902A (en) 2021-02-10
JP2021524250A (en) 2021-09-13
DOP2020000216A (en) 2021-09-15
NI202000086A (en) 2021-03-23
WO2019224718A2 (en) 2019-11-28
CN112513085A (en) 2021-03-16
US20200024360A1 (en) 2020-01-23
ECSP20082991A (en) 2021-01-29
TW202016135A (en) 2020-05-01
MX2020012598A (en) 2021-05-27
PH12020551997A1 (en) 2021-09-06
UY38244A (en) 2019-11-29
JOP20200303A1 (en) 2020-11-23
BR112020023872A2 (en) 2021-02-17
CL2020003031A1 (en) 2021-04-16

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