BR112015018418A2 - métodos para tratar câncer, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir o desenvolvimento de câncer, para aumentar a sensibilidade a um terapêutico direcionado, para estender o período de sensibilidade, para estender a duração de resposta a um terapêutico direcionado e produto farmacêutico - Google Patents

métodos para tratar câncer, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir o desenvolvimento de câncer, para aumentar a sensibilidade a um terapêutico direcionado, para estender o período de sensibilidade, para estender a duração de resposta a um terapêutico direcionado e produto farmacêutico

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Publication number
BR112015018418A2
BR112015018418A2 BR112015018418A BR112015018418A BR112015018418A2 BR 112015018418 A2 BR112015018418 A2 BR 112015018418A2 BR 112015018418 A BR112015018418 A BR 112015018418A BR 112015018418 A BR112015018418 A BR 112015018418A BR 112015018418 A2 BR112015018418 A2 BR 112015018418A2
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BR
Brazil
Prior art keywords
extending
increasing
sensitivity
targeted therapy
treatment
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BR112015018418A
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English (en)
Inventor
Raha Debasish
Settleman Jeffrey
R Wilson Timothy
Original Assignee
Hoffmann La Roche
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112015018418A2 publication Critical patent/BR112015018418A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

resumo “métodos para tratar câncer, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir o desenvolvimento de câncer, para aumentar a sensibilidade a um terapêutico direcionado, para estender o período de sensibilidade, para estender a duração de resposta a um terapêutico direcionado e produto farmacêutico” no presente pedido são fornecidos produtos farmacêuticos que compreendem combinações terapeuticamente efetivas de inibidores de aldh (por exemplo, dissulfiram e/ou derivados do mesmo) e terapêuticos direcionados, bem como métodos para usar as ditas combinações para o tratamento de câncer.
BR112015018418A 2013-02-22 2014-02-21 métodos para tratar câncer, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir o desenvolvimento de câncer, para aumentar a sensibilidade a um terapêutico direcionado, para estender o período de sensibilidade, para estender a duração de resposta a um terapêutico direcionado e produto farmacêutico BR112015018418A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361768253P 2013-02-22 2013-02-22
US201361834317P 2013-06-12 2013-06-12
PCT/EP2014/053377 WO2014128235A1 (en) 2013-02-22 2014-02-21 Methods of treating cancer and preventing drug resistance

Publications (1)

Publication Number Publication Date
BR112015018418A2 true BR112015018418A2 (pt) 2017-07-18

Family

ID=50179591

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015018418A BR112015018418A2 (pt) 2013-02-22 2014-02-21 métodos para tratar câncer, para aumentar a eficácia de um tratamento, para adiar e/ou prevenir o desenvolvimento de câncer, para aumentar a sensibilidade a um terapêutico direcionado, para estender o período de sensibilidade, para estender a duração de resposta a um terapêutico direcionado e produto farmacêutico

Country Status (9)

Country Link
EP (1) EP2958592A1 (pt)
JP (1) JP2016509045A (pt)
KR (1) KR20150118159A (pt)
CN (1) CN104994879A (pt)
BR (1) BR112015018418A2 (pt)
CA (1) CA2900097A1 (pt)
HK (1) HK1211235A1 (pt)
MX (1) MX2015010791A (pt)
WO (1) WO2014128235A1 (pt)

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CA2900097A1 (en) 2014-08-28
CN104994879A (zh) 2015-10-21
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