EA201790173A1 - Антитела, связывающие axl - Google Patents

Антитела, связывающие axl

Info

Publication number
EA201790173A1
EA201790173A1 EA201790173A EA201790173A EA201790173A1 EA 201790173 A1 EA201790173 A1 EA 201790173A1 EA 201790173 A EA201790173 A EA 201790173A EA 201790173 A EA201790173 A EA 201790173A EA 201790173 A1 EA201790173 A1 EA 201790173A1
Authority
EA
Eurasian Patent Office
Prior art keywords
axl
antibodies
antibodies connecting
immunoconjugates
compositions
Prior art date
Application number
EA201790173A
Other languages
English (en)
Inventor
Эстер Брей
Давид Сатейн
Эдвард Норберт Ван Ден Бринк
Деннис Верзейл
Роб Н. Де Йонг
Паул Паррен
Римке Ван Дейкхёйзен Радерсма
Original Assignee
Генмаб А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Генмаб А/С filed Critical Генмаб А/С
Publication of EA201790173A1 publication Critical patent/EA201790173A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

Настоящее изобретение относится к анти-AXL антителам, иммуноконъюгатам, композициям и способу лечения рака такими анти-AXL антителами, иммуноконъюгатами или композициями.
EA201790173A 2014-07-11 2015-07-10 Антитела, связывающие axl EA201790173A1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201400380 2014-07-11
DKPA201400489 2014-09-01
DKPA201400746 2014-12-22
DKPA201500283 2015-05-12
PCT/EP2015/065900 WO2016005593A1 (en) 2014-07-11 2015-07-10 Antibodies binding axl

Publications (1)

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